Receptor
PDB id Resolution Class Description Source Keywords
1A8A 1.9 Å NON-ENZYME: OTHER RAT ANNEXIN V COMPLEXED WITH GLYCEROPHOSPHOSERINE RATTUS NORVEGICUS PHOSPHOLIPID ANALOG CALCIUM BINDING PROTEIN MEMBRANE BINDING PROTEIN
Ref.: CA(2+)-BRIDGING MECHANISM AND PHOSPHOLIPID HEAD GROUP RECOGNITION IN THE MEMBRANE-BINDING PROTEIN ANNEXIN V. NAT.STRUCT.BIOL. V. 2 968 1995
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
CA A:401;
A:402;
A:403;
A:404;
A:405;
A:406;
A:407;
A:408;
A:409;
A:410;
 Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
 none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
 submit data
40.078 Ca [Ca+2...
GSE A:997;
 Valid;
 none;
 submit data
259.151 C6 H14 N O8 P C([C@...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1G5N 1.9 Å NON-ENZYME: OTHER ANNEXIN V COMPLEX WITH HEPARIN OLIGOSACCHARIDES RATTUS NORVEGICUS HELIX-BUNDLE MEMBRANE BINDING HEPARIN HEPARAN SULFATE BLCLOTTING
Ref.: ANNEXIN V--HEPARIN OLIGOSACCHARIDE COMPLEX SUGGESTS SULFATE--MEDIATED ASSEMBLY ON CELL SURFACES. STRUCTURE V. 9 57 2001
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1610 families.
1 1A8B - GPE C5 H14 N O6 P C(CO[P@](=....
2 1A8A - GSE C6 H14 N O8 P C([C@H](CO....
3 1G5N - SGN IDS SGN UAP n/a n/a
70% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1331 families.
1 1A8B - GPE C5 H14 N O6 P C(CO[P@](=....
2 1A8A - GSE C6 H14 N O8 P C([C@H](CO....
3 1G5N - SGN IDS SGN UAP n/a n/a
50% Homology Family (7)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1144 families.
1 6TWU Kd ~ 1 mM SER SER ARG THR ARG ARG GLU GLU GLN LEU n/a n/a
2 6TWX Kd ~ 2.5 mM SER SER ARG THR ARG ARG GLU TPO GLN LEU n/a n/a
3 2HYU - SGN IDS SGN UAP n/a n/a
4 2HYV - IDS SGN IDS SGN UAP n/a n/a
5 1A8B - GPE C5 H14 N O6 P C(CO[P@](=....
6 1A8A - GSE C6 H14 N O8 P C([C@H](CO....
7 1G5N - SGN IDS SGN UAP n/a n/a
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: GSE; Similar ligands found: 12
No: Ligand ECFP6 Tc MDL keys Tc
1 GSE 1 1
2 GPE 0.522727 0.840909
3 LPS 0.516667 0.784314
4 SEP 0.512195 0.833333
5 CH5 0.44898 0.636364
6 S12 0.442857 0.784314
7 PSF 0.430769 0.784314
8 G3P 0.414634 0.714286
9 1GP 0.414634 0.714286
10 8SP 0.411765 0.784314
11 P5S 0.405797 0.784314
12 44G 0.4 0.666667
Similar Ligands (3D)
Ligand no: 1; Ligand: GSE; Similar ligands found: 2
No: Ligand Similarity coefficient
1 FOB 0.8549
2 G01 0.8523
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1G5N; Ligand: SGN IDS SGN UAP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 1g5n.bio1) has 8 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 1G5N; Ligand: SGN IDS SGN UAP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 1g5n.bio1) has 10 residues
No: Leader PDB Ligand Sequence Similarity
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