Receptor
PDB id Resolution Class Description Source Keywords
1PCX 2.5 Å NON-ENZYME: TRANSPORT CRYSTAL STRUCTURE OF THE COPII COAT SUBUNIT, SEC24, COMPLEXED WITH A PEPTIDE FROM THE SNARE PROTEIN BET1 SACCHAROMYCES CEREVISIAE TRANSPORT PROTEIN
Ref.: SNARE SELECTIVITY OF THE COPII COAT. CELL(CAMBRIDGE,MASS.) V. 114 483 2003
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
LEU ALA SER LEU GLU SER GLN SER B:483;
 Valid;
 none;
 submit data
832.886 n/a O=C([...
ZN A:950;
 Part of Protein;
 none;
 submit data
65.409 Zn [Zn+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1PCX 2.5 Å NON-ENZYME: TRANSPORT CRYSTAL STRUCTURE OF THE COPII COAT SUBUNIT, SEC24, COMPLEXED WITH A PEPTIDE FROM THE SNARE PROTEIN BET1 SACCHAROMYCES CEREVISIAE TRANSPORT PROTEIN
Ref.: SNARE SELECTIVITY OF THE COPII COAT. CELL(CAMBRIDGE,MASS.) V. 114 483 2003
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 232 families.
1 1PCX - LEU ALA SER LEU GLU SER GLN SER n/a n/a
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 197 families.
1 1PCX - LEU ALA SER LEU GLU SER GLN SER n/a n/a
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 165 families.
1 1PCX - LEU ALA SER LEU GLU SER GLN SER n/a n/a
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: LEU ALA SER LEU GLU SER GLN SER; Similar ligands found: 69
No: Ligand ECFP6 Tc MDL keys Tc
1 LEU ALA SER LEU GLU SER GLN SER 1 1
2 SER LEU SER GLN SER LEU SER GLN SER 0.546512 0.977273
3 ASP PHE GLN GLU SER ALA ASP SER PHE LEU 0.537037 0.88
4 SER GLN LEU LYS ASN ASN ALA LYS GLU ILE 0.518868 0.88
5 GLU ALA THR GLN LEU MET ASN 0.495146 0.836735
6 SER ALA GLU PRO VAL PRO LEU GLN LEU 0.486957 0.733333
7 LYS SER LEU LEU GLN GLN LEU LEU THR GLU 0.481132 0.916667
8 LEU GLU LEU ASP LYS TRP ALA SER LEU 0.472 0.77193
9 SER SER LEU GLU ASN PHE ALA ALA TYR VAL 0.471074 0.796296
10 TYR GLN SER LYS LEU 0.460784 0.811321
11 ACE VAL LYS GLU SER LEU VAL 0.459184 0.934783
12 GLU GLU TYR LEU GLN ALA PHE THR TYR 0.458333 0.754717
13 SER GLY ILE PHE LEU GLU THR SER 0.457944 0.877551
14 ASN SER THR LEU GLN 0.457447 0.913043
15 PHE GLU ASP LEU ARG LEU LEU SER PHE 0.456897 0.785714
16 GLU LEU GLU LYS TRP ALA SER 0.453782 0.706897
17 ALA LYS ALA SER GLN ALA ALA 0.447917 0.869565
18 ACE GLN LEU VAL THR SER LEU 0.447917 0.934783
19 PHE ASN GLU LEU SER HIS LEU 0.446602 0.763636
20 GLY THR LEU SER ASN ARG ALA SER LYS LEU 0.445652 0.913043
21 LEU ALA ILE TYR SER 0.445545 0.730769
22 ACE ASP LEU GLN THR SER ILE 0.441176 0.914894
23 GLU ALA GLN THR ARG LEU 0.440367 0.807692
24 LEU TYR ALA SER PRO GLN LEU GLU GLY PHE 0.438849 0.636364
25 PRO GLU SEP LEU GLU SER CYS PHE 0.4375 0.767857
26 ALA ALA SER LEU TYR GLU LYS LYS ALA ALA 0.434783 0.796296
27 ALA LYS GLU LYS SER ASP 0.434783 0.87234
28 LEU LEU LEU 0.434211 0.727273
29 ALA GLU ALA ALA GLN ALA 0.433333 0.772727
30 LEU GLU PHE GLN GLY 0.431373 0.77551
31 GLU ALA ASP LYS TRP GLN SER 0.430894 0.689655
32 ACE GLY ALA ALA GLN GLU GLU 0.430108 0.765957
33 PHE LEU GLU LYS 0.43 0.77551
34 ALA SER ASN GLU ASN ALA GLU THR MET 0.429907 0.843137
35 SER SER ARG THR ARG ARG GLU GLU GLN LEU 0.428571 0.818182
36 ARG LEU GLN ARG ARG ARG GLU THR GLN VAL 0.427273 0.811321
37 ILE SER GLU VAL 0.426966 0.933333
38 ASP ALA ASP GLU TYR LEU 0.424528 0.745098
39 PHE GLU ASP LEU ARG VAL LEU SER PHE 0.420635 0.785714
40 PHE GLU ASP LEU ARG VAL SER SER PHE 0.420635 0.785714
41 SER GLN TYR TYR TYR ASN SER LEU 0.420561 0.796296
42 ARG GLN ALA SEP LEU SER ILE SER VAL 0.419355 0.745763
43 ILE GLU GLU ALA LEU GLN ILE ILE HIS SER 0.419355 0.732143
44 THR GLU ASN LEU TYR PHE GLN SER GLY THR 0.417323 0.785714
45 HIS GLU GLU LEU ALA LYS LEU 0.416667 0.826087
46 SER SER LEU GLU ASN PHE ARG ALA TYR VAL 0.416058 0.721311
47 GLU LEU ASP LYS TYR ALA SER 0.413793 0.811321
48 GLN ALA SER GLN GLU VAL LYS ASN TRP 0.413534 0.728814
49 LYS LEU VAL GLN LEU LEU THR THR THR 0.413462 0.914894
50 THR SER ASN LEU GLN GLU GLN ILE GLY TRP 0.411765 0.733333
51 GLY ASN PHE LEU GLN SER ARG 0.411765 0.785714
52 ALA GLN PHE SER ALA SER ALA SER ARG 0.410714 0.777778
53 VAL ARG SER ARG ARG ABA LEU ARG LEU 0.409524 0.811321
54 ACE MET LEU SER VAL GLU GLU GLU GLY 0.409524 0.823529
55 SER ARG MET GLU GLU VAL ASP 0.407407 0.897959
56 ILE PRO LEU THR GLU GLU ALA GLU LEU 0.40678 0.672131
57 ACE GLU ALA GLN THR ARG LEU 0.405405 0.792453
58 SER HIS VAL ALA VAL GLU ASN ALA LEU 0.404959 0.781818
59 GLU GLN ASP LYS TRP ALA SER 0.404762 0.689655
60 SER SER ILE GLU PHE ALA ARG LEU 0.404762 0.8
61 VAL GLN GLN GLU SER SER PHE VAL MET 0.403509 0.862745
62 CYS THR GLU LEU LYS LEU SER ASP TYR 0.403226 0.814815
63 ILE LEU SER ALA LEU VAL GLY ILE LEU 0.401869 0.891304
64 ILE LEU SER ALA LEU VAL GLY ILE VAL 0.401869 0.891304
65 ACE ILE TYR GLU SER LEU 0.401869 0.788462
66 ASP GLU LEU GLU ILE LYS ALA TYR 0.401639 0.727273
67 LYS SER HIS GLN GLU 0.4 0.684211
68 PHE ALA GLN 0.4 0.659574
69 GLU LEU ASP ORN TRP ALA SER 0.4 0.767857
Similar Ligands (3D)
Ligand no: 1; Ligand: LEU ALA SER LEU GLU SER GLN SER; Similar ligands found: 0
No: Ligand Similarity coefficient
Similar Binding Sites (Proteins are less than 50% similar to leader) APoc FAQ
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