Receptor
PDB id Resolution Class Description Source Keywords
5DL0 2.3 Å EC: 7.-.-.- CRYSTAL STRUCTURE OF GLUCOSIDASE II ALPHA SUBUNIT (GLC1MAN2- FROM) CHAETOMIUM THERMOPHILUM (STRAIN DSM 14144.50 / IMI 039719) ENDOPLASMIC RETICULUM GLYCOSIDE HYDROLASE GLYCOSYLATION H
Ref.: STRUCTURAL BASIS FOR TWO-STEP GLUCOSE TRIMMING BY GLUCOSIDASE II INVOLVED IN ER GLYCOPROTEIN QUALITY SCI REP V. 6 20575 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
MAN GLC B:1;
Valid;
none;
submit data
n/a n/a
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5DKY 1.6 Å EC: 7.-.-.- CRYSTAL STRUCTURE OF GLUCOSIDASE II ALPHA SUBUNIT (DNJ-BOUND CHAETOMIUM THERMOPHILUM (STRAIN DSM 14144.50 / IMI 039719) ENDOPLASMIC RETICULUM GLYCOSIDE HYDROLASE GLYCOSYLATION H
Ref.: STRUCTURAL BASIS FOR TWO-STEP GLUCOSE TRIMMING BY GLUCOSIDASE II INVOLVED IN ER GLYCOPROTEIN QUALITY SCI REP V. 6 20575 2016
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 319 families.
1 5DKZ - GLC GLC n/a n/a
2 5DL0 - MAN GLC n/a n/a
3 5DKY - NOJ C6 H13 N O4 C1[C@@H]([....
70% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 271 families.
1 5DKZ - GLC GLC n/a n/a
2 5DL0 - MAN GLC n/a n/a
3 5DKY - NOJ C6 H13 N O4 C1[C@@H]([....
50% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 223 families.
1 5DKZ - GLC GLC n/a n/a
2 5DL0 - MAN GLC n/a n/a
3 5DKY - NOJ C6 H13 N O4 C1[C@@H]([....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: MAN GLC; Similar ligands found: 0
No: Ligand ECFP6 Tc MDL keys Tc
Similar Ligands (3D)
Ligand no: 1; Ligand: MAN GLC; Similar ligands found: 38
No: Ligand Similarity coefficient
1 MAN GLC 1.0000
2 GLC GLC 0.9758
3 MAN MAN 0.9624
4 GLC DMJ 0.9511
5 MMA MAN 0.9474
6 GLC IFM 0.9409
7 ZEL MAN 0.9343
8 GDQ GLC 0.9311
9 MAN G63 0.9311
10 DGO MAN 0.9298
11 MAN MNM 0.9296
12 FRU GLC 0.9295
13 GLA GLA 0.9199
14 MAN IFM 0.9181
15 GLC 7LQ 0.9172
16 7D1 MAN 0.9170
17 DGO Z61 0.9152
18 RZM 0.9064
19 BGC GLC 0.9060
20 Z4R MAN 0.9047
21 GAL GLA 0.8996
22 RAM GAD 0.8979
23 RR7 GLC 0.8972
24 BDF GLC 0.8942
25 NOJ GLC 0.8941
26 SGC GLC 0.8888
27 BGC BGC 0.8877
28 GLC BGC 0.8860
29 MAN MVL 0.8854
30 MYG 0.8811
31 MA1 GLC 0.8809
32 DTK 0.8777
33 XYP GCU 0.8765
34 TW7 GLC 0.8755
35 GLF B8D 0.8662
36 DSQ 0.8626
37 F9W 0.8579
38 7D0 0.8563
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5DKY; Ligand: NOJ; Similar sites found with APoc: 8
This union binding pocket(no: 1) in the query (biounit: 5dky.bio1) has 20 residues
No: Leader PDB Ligand Sequence Similarity
1 4AMW 5DI 24.0799
2 3LPP KTL 33.7416
3 3LPP KTL 33.7416
4 3L4U DSK 36.8
5 5NN6 MIG 38.1881
6 3WEO GLC GLC GLC GLC GLC GLC AC1 39.8686
7 3MKK BGC GLC 41.1411
8 3MKK GLC BGC 41.1411
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