Receptor
PDB id Resolution Class Description Source Keywords
3OBU 1.6 Å NON-ENZYME: TRANSCRIPT_TRANSLATE CRYSTAL STRUCTURE OF THE TSG101 UEV DOMAIN IN COMPLEX WITH A PTAP PEPTIDE HOMO SAPIENS PROTEIN TRANPORT UBIQUITIN HIV-1 GAG PROTEIN TRANSPORT
Ref.: CRYSTALLOGRAPHIC AND FUNCTIONAL ANALYSIS OF THE ESC /HIV-1 GAG PTAP INTERACTION. STRUCTURE V. 18 1536 2010
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
PRO GLU PRO THR ALA PRO PRO GLU GLU B:5;
 Valid;
 none;
 Kd = 50 uM
962.988 n/a O=C([...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3OBU 1.6 Å NON-ENZYME: TRANSCRIPT_TRANSLATE CRYSTAL STRUCTURE OF THE TSG101 UEV DOMAIN IN COMPLEX WITH A PTAP PEPTIDE HOMO SAPIENS PROTEIN TRANPORT UBIQUITIN HIV-1 GAG PROTEIN TRANSPORT
Ref.: CRYSTALLOGRAPHIC AND FUNCTIONAL ANALYSIS OF THE ESC /HIV-1 GAG PTAP INTERACTION. STRUCTURE V. 18 1536 2010
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 308 families.
1 3OBQ Kd = 290 uM PRO THR PRO SER ALA PRO VAL PRO LEU n/a n/a
2 3OBU Kd = 50 uM PRO GLU PRO THR ALA PRO PRO GLU GLU n/a n/a
3 3OBX Kd = 130 uM PRO GLU ALA THR ALA PRO PRO GLU GLU n/a n/a
70% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 266 families.
1 3OBQ Kd = 290 uM PRO THR PRO SER ALA PRO VAL PRO LEU n/a n/a
2 3OBU Kd = 50 uM PRO GLU PRO THR ALA PRO PRO GLU GLU n/a n/a
3 3OBX Kd = 130 uM PRO GLU ALA THR ALA PRO PRO GLU GLU n/a n/a
50% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 220 families.
1 3OBQ Kd = 290 uM PRO THR PRO SER ALA PRO VAL PRO LEU n/a n/a
2 3OBU Kd = 50 uM PRO GLU PRO THR ALA PRO PRO GLU GLU n/a n/a
3 3OBX Kd = 130 uM PRO GLU ALA THR ALA PRO PRO GLU GLU n/a n/a
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: PRO GLU PRO THR ALA PRO PRO GLU GLU; Similar ligands found: 52
No: Ligand ECFP6 Tc MDL keys Tc
1 PRO GLU PRO THR ALA PRO PRO GLU GLU 1 1
2 PRO GLU ALA THR ALA PRO PRO GLU GLU 0.818182 1
3 LYS THR PHE PRO PRO THR GLU PRO LYS 0.521127 0.95082
4 ACE GLU VAL ALA PRO PRO VAL LPD 0.504 0.883333
5 PRO THR PRO SER ALA PRO VAL PRO LEU 0.5 0.935484
6 ALA PRO THR MET PRO PRO PRO LEU PRO PRO 0.469231 0.876923
7 GLN PRO PRO VAL PRO PRO GLN ARG PRO MET 0.458904 0.746479
8 ALA THR PRO PHE GLN GLU 0.455882 0.868852
9 SER ALA GLU PRO VAL PRO LEU GLN LEU 0.453237 0.919355
10 ALA PRO GLN PRO ALA PRO GLU ASN ALA TYR 0.452055 0.890625
11 PRO SER TYR SEP PRO THR SEP PRO SER 0.451389 0.788732
12 TYR LEU GLU PRO ALA PRO VAL THR ALA 0.448276 0.892308
13 PRO THR VAL GLU GLU VAL ASP 0.446281 0.833333
14 SER GLU CYS THR THR PRO CYS 0.442748 0.918033
15 ACE GLU VAL ASN PRO PRO VAL PRO NH2 0.441176 0.901639
16 PRO PRO PRO VAL PRO PRO ARG ARG ARG ARG 0.440298 0.757576
17 PRO GLN PTR GLU GLU ILE PRO ILE 0.44 0.75
18 LEU PRO PRO VAL VAL ALA LYS GLU ILE 0.438356 0.854839
19 PRO GLN PTR GLU PTR ILE PRO ALA 0.437086 0.72973
20 ACE GLU VAL ASN PRO PRO VAL LPD 0.437037 0.901639
21 THR PRO PRO SER PRO PHE 0.433071 0.887097
22 BOC ALA ALA PRO GLU 0.429752 0.769231
23 VAL PRO LEU THR GLU ASP ALA GLU LEU 0.428571 0.901639
24 PHE TYR ALA PRO GLU PRO ILE THR SER LEU 0.427673 0.855072
25 GLN MET PRO THR GLU ASP GLU TYR 0.427632 0.838235
26 ILE PRO LEU THR GLU GLU ALA GLU LEU 0.427536 0.887097
27 PRO PRO GLY PRO GLU GLY PRO PRO GLY 0.427481 0.864407
28 GLY TYR GLN ASP TYR GLU PRO GLU ALA 0.426471 0.825397
29 LEU PRO SER PHE GLU THR ALA LEU 0.425676 0.875
30 GLY ARG PRO ARG THR THR SER PHE ALA GLU 0.425 0.838235
31 PRO PRO THR LEU HIS GLU LEU TYR ASP LEU 0.42236 0.84058
32 LEU PRO GLU THR GLY 0.420635 0.901639
33 GLU GLU PRO THR VAL ILE LYS LYS TYR 0.420382 0.863636
34 GLN ASN GLY PTR GLU ASN PRO THR TYR 0.42 0.788732
35 LEU PRO PRO GLU GLU ARG LEU ILE 0.41958 0.764706
36 PRO LYS ARG PRO THR THR LEU ASN LEU PHE 0.419162 0.814286
37 ASP TYR GLU PRO ILE PRO GLU GLU ALA PHE 0.417722 0.820895
38 SER MET PRO GLU LEU SER PRO VAL LEU 0.417266 0.863636
39 PRO PRO PRO ALA LEU PRO PRO LYS LYS ARG 0.415493 0.819672
40 PRO GLN PTR ILE PTR VAL PRO ALA 0.414474 0.72
41 LYS GLY PRO PRO LEU PRO ARG PRO ARG VAL 0.411765 0.746269
42 ACE PRO ILE GLN GLU GLU 0.41129 0.822581
43 PRO THR SER SER GLU GLN ILE 0.407692 0.806452
44 ASP VAL GLN THR GLY ARG ARG PRO TYR GLU 0.407407 0.828571
45 ASN LEU VAL PRO GLN VAL ALA THR VAL 0.406897 0.887097
46 PRO ARG ARG PRO VAL ILE MET ARG ARG 0.406667 0.694444
47 GLU PRO VAL GLU THR THR ASP TYR 0.40411 0.875
48 ACE GLU VAL ASN ALA PRO VAL LPD 0.402985 0.901639
49 PRO PRO PRO MET ALA GLY GLY 0.40146 0.84375
50 ARG ARG ARG GLU ARG SER PRO THR ARG 0.401361 0.848485
51 TYR LEU GLU PRO GLY PRO VAL THR VAL 0.4 0.892308
52 TYR LEU GLU PRO GLY PRO VAL THR ALA 0.4 0.892308
Similar Ligands (3D)
Ligand no: 1; Ligand: PRO GLU PRO THR ALA PRO PRO GLU GLU; Similar ligands found: 0
No: Ligand Similarity coefficient
Similar Binding Sites (Proteins are less than 50% similar to leader) APoc FAQ
Feedback