 
PDB ID
|
Resolution
|
Source
|
Class
|
Ligands
|
Binding Data
|
Molecular Weight (Da)
|
|---|---|---|---|---|---|---|
| 2VFI | 2.25 | PLASMODIUM FALCIPARUM | ENZYME 5.3.1.1 | 3PG | Ki = 1.9 mM | 186.057 |
| 4FGZ | 1.99 | PLASMODIUM FALCIPARUM | ENZYME 2.1.1.103 | SAH, PO4, CQA | ic50 = 1350 uM | 384.411, 94.971, 355.861 |
| 1CET | 2.05 | PLASMODIUM FALCIPARUM | ENZYME 1.1.1.27 | CLQ | Ki = 1.3 mM | 319.872 |
| 6R8G | 2 | PLASMODIUM FALCIPARUM | ENZYME 1.1.1.37 | NAD, JUT, NA | Kd = 172 uM | 663.425, 212.219, 22.99 |
| 4ZW5 | 1.8 | PLASMODIUM FALCIPARUM | ENZYME 3.4.11.- | ZN, 4SA, MG | Ki = 37 uM | 65.409, 342.389, 24.305 |
| 2AAW | 2.4 | PLASMODIUM FALCIPARUM | ENZYME 2.5.1.18 | P33, DTL, GTX | Ki = 35 uM | 326.383, 122.12, 392.491 |
| 2PT9 | 2.2 | PLASMODIUM FALCIPARUM | ENZYME 2.5.1.16 | SO4, S4M, GOL, 2MH, 1PG | ic50 = 35 uM | 96.063, 356.444, 92.094, 113.201, 252.305 |
| 2YOG | 1.5 | PLASMODIUM FALCIPARUM | ENZYME 2.7.4.9 | 74X | Ki = 31 uM | 478.873 |
| 1LYX | 1.9 | PLASMODIUM FALCIPARUM | ENZYME 5.3.1.1 | PGA | Ki = 0.029 mM | 156.031 |
| 3UJC | 1.19 | PLASMODIUM FALCIPARUM | ENZYME 2.1.1.103 | PC | Kd = 26 uM | 184.151 |
| 2YOF | 1.82 | PLASMODIUM FALCIPARUM | ENZYME 2.7.4.9 | 74W, TAM, ACT | Ki = 25 uM | 478.873, 163.215, 59.044 |
| 3UJ9 | 1.24 | PLASMODIUM FALCIPARUM | ENZYME 2.1.1.103 | PC | Kd = 23.4 uM | 184.151 |
| 3UJD | 1.5 | PLASMODIUM FALCIPARUM | ENZYME 2.1.1.103 | PC | Kd = 20.2 uM | 184.151 |
| 6FBA | 2 | PLASMODIUM FALCIPARUM | ENZYME 2.1.3.2 | MLI, D48, GOL, PEG, NA, SO4, DMS | Kd = 19.9 uM | 102.046, 160.169, 92.094, 106.12, 22.99, 96.063, 78.133 |
| 3S9Y | 1.7 | PLASMODIUM FALCIPARUM | ENZYME 4.1.1.23 | SO4, PGE, PEG, P6G, FNU | Ki = 16.6 uM | 96.063, 150.173, 106.12, 282.331, 357.186 |
| 1NHW | 2.35 | PLASMODIUM FALCIPARUM | ENZYME 1.3.1.9 | TCC, NAD | Ki = 14.3 uM | 254.112, 663.425 |
| 6I55 | 1.98 | PLASMODIUM FALCIPARUM | ENZYME 1.3.5.2 | ORO, DZB, FMN | ic50 = 12 uM | 156.096, 325.385, 456.344 |
| 2YOH | 1.6 | PLASMODIUM FALCIPARUM | ENZYME 2.7.4.9 | WMJ | Ki = 11 uM | 405.362 |
| 5ZNI | 2.3 | PLASMODIUM FALCIPARUM | ENZYME 2.4.2.1 | YMZ, PO4 | Kd = 11 uM | 378.312, 94.971 |
| 2I7C | 1.71 | PLASMODIUM FALCIPARUM | ENZYME 2.5.1.16 | AAT, 1PG, GOL | ic50 = 8.5 uM | 423.533, 252.305, 92.094 |
| 4IGF | 2.3 | PLASMODIUM FALCIPARUM | ENZYME 1.3.1.9 | CHV, GOL, NAD, SO4 | ic50 = 6 uM | 304.682, 92.094, 663.425, 96.063 |
| 1V0O | 1.9 | PLASMODIUM FALCIPARUM | ENZYME 2.7.1.22 | INR | ic50 = 5.5 uM | 342.326 |
| 4R6W | 1.59 | PLASMODIUM FALCIPARUM | ENZYME 2.1.1.103 | SAH, PC | Kd = 5.4 uM | 384.411, 184.151 |
| 4WI1 | 1.65 | PLASMODIUM FALCIPARUM | ENZYME 6.1.1.15 | 3O6, MG, CL, IMD, EDO | ic50 = 5 uM | 396.314, 24.305, 35.453, 69.085, 62.068 |
| 1VYQ | 2.4 | PLASMODIUM FALCIPARUM | ENZYME 3.6.1.23 | DUX | Ki = 4.98 uM | 472.508 |
| 3JQQ | 2.2 | PLASMODIUM FALCIPARUM | ENZYME 1.18.1.2 | FAD, A2P | Ki = 2.9 uM | 785.55, 427.201 |
| 6I4B | 1.98 | PLASMODIUM FALCIPARUM | ENZYME 1.3.5.2 | E2N, ORO, FMN | ic50 = 2.8 uM | 316.233, 156.096, 456.344 |
| 2Q8Z | 1.8 | PLASMODIUM FALCIPARUM | ENZYME 4.1.1.23 | SO4, PEG, NUP, 7PE | Ki = 2.1 uM | 96.063, 106.12, 339.196, 310.384 |
| 4ZW6 | 1.9 | PLASMODIUM FALCIPARUM | ENZYME 3.4.11.- | MG, DMS, PO4, 4SY, ZN, GOL | Ki = 1.9 uM | 24.305, 78.133, 94.971, 346.381, 65.409, 92.094 |
| 1T25 | 1.9 | PLASMODIUM FALCIPARUM | ENZYME 1.1.1.27 | NAI, GOL, GAG | ic50 = 1.1 uM | 665.441, 92.094, 129.071 |
| 4ZW8 | 2 | PLASMODIUM FALCIPARUM | ENZYME 3.4.11.- | 4T2, ZN, GOL, DMS | Ki = 1.1 uM | 400.428, 65.409, 92.094, 78.133 |
| 1TV5 | 2.4 | PLASMODIUM FALCIPARUM | ENZYME 1.3.5.2 | SO4, ORO, N8E, FMN, A26 | Ki ~ 1000 nM | 96.063, 156.096, 350.491, 456.344, 270.207 |
| 1T24 | 1.7 | PLASMODIUM FALCIPARUM | ENZYME 1.1.1.27 | OXQ, NAD, GOL | ic50 = 0.65 uM | 130.059, 663.425, 92.094 |
| 4ZX5 | 1.95 | PLASMODIUM FALCIPARUM | ENZYME 3.4.11.- | 4TM, GOL, MG, DMS, ZN | Ki = 0.64 uM | 332.417, 92.094, 24.305, 78.133, 65.409 |
| 3T70 | 1.8 | PLASMODIUM FALCIPARUM | ENZYME 3.6.1.23 | SO4, GLY HIS GLY, DU4 | Ki = 0.5 uM | 96.063, 254.27, 407.462 |
| 3EBH | 1.65 | PLASMODIUM FALCIPARUM | ENZYME 3.4.11.- | ZN, MG, GOL, BES | Ki = 478.2 nM | 65.409, 24.305, 92.094, 308.373 |
| 2FOI | 2.5 | PLASMODIUM FALCIPARUM | ENZYME 1.3.1.9 | NAD, JPA | ic50 = 440 nM | 663.425, 345.219 |
| 2OL4 | 2.26 | PLASMODIUM FALCIPARUM | ENZYME 1.3.1.9 | NAD, JPN | ic50 = 440 nM | 663.425, 373.272 |
| 2Y8C | 2.1 | PLASMODIUM FALCIPARUM | ENZYME 3.6.1.23 | SO4, DUQ | Ki = 0.4 uM | 96.063, 513.584 |
| 3LT2 | 2.5 | PLASMODIUM FALCIPARUM | ENZYME 1.3.1.9 | NAD, FT3 | Ki = 0.38 uM | 663.425, 285.123 |
| 3T8W | 2 | PLASMODIUM FALCIPARUM | ENZYME 3.4.11.1 | ZN, SO4, DGZ, CO3, 2PE, 1PE | Ki = 330 nM | 65.409, 96.063, 1010.18, 60.009, 414.488, 238.278 |
| 2NQ8 | 2.5 | PLASMODIUM FALCIPARUM | ENZYME 1.3.1.9 | ZID | ic50 = 320 nM | 768.519 |
| 3LT1 | 2.2 | PLASMODIUM FALCIPARUM | ENZYME 1.3.1.9 | FT2, NAD | Ki = 0.32 uM | 303.568, 663.425 |
| 4YDQ | 2.3 | PLASMODIUM FALCIPARUM | ENZYME 6.1.1.15 | HFG, MG, ANP | Kd ~ 300 nM | 414.681, 24.305, 506.196 |
| 4Q15 | 2.35 | PLASMODIUM FALCIPARUM | ENZYME 6.1.1.15 | HFG, ANP, EDO, MG | ic50 = 275 nM | 414.681, 506.196, 62.068, 24.305 |
| 3T8V | 1.8 | PLASMODIUM FALCIPARUM | ENZYME 3.4.11.- | ZN, MG, BTJ | Ki = 260 nM | 65.409, 24.305, 990.15 |
| 4IGE | 2.15 | PLASMODIUM FALCIPARUM | ENZYME 1.3.1.9 | SO4, GOL, NAD, CHJ | ic50 = 0.25 uM | 96.063, 92.094, 663.425, 302.709 |
| 7BT5 | 2.49 | PLASMODIUM FALCIPARUM | ENZYME 6.1.1.6 | LYS, F6O | Kd = 239 nM | 147.195, 580.745 |
| 3T60 | 2.4 | PLASMODIUM FALCIPARUM | ENZYME 3.6.1.23 | GOL, DUA | Ki = 0.2 uM | 92.094, 469.532 |
| 3LT0 | 1.96 | PLASMODIUM FALCIPARUM | ENZYME 1.3.1.9 | NAD, FT1 | Ki = 0.18 uM | 663.425, 283.107 |
