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1.- Oxidoreductases
1.1.-.-
1.1.1.-
1.1.1.1
1.1.1.2
1.1.1.3
1.1.1.5
1.1.1.6
1.1.1.8
1.1.1.9
1.1.1.10
1.1.1.14
1.1.1.16
1.1.1.18
1.1.1.21
1.1.1.22
1.1.1.23
1.1.1.25
1.1.1.26
1.1.1.27
1.1.1.28
1.1.1.30
1.1.1.31
1.1.1.34
1.1.1.35
1.1.1.37
1.1.1.38
1.1.1.40
1.1.1.42
1.1.1.44
1.1.1.47
1.1.1.49
1.1.1.50
1.1.1.53
1.1.1.62
1.1.1.67
1.1.1.69
1.1.1.77
1.1.1.79
1.1.1.85
1.1.1.86
1.1.1.87
1.1.1.88
1.1.1.90
1.1.1.93
1.1.1.95
1.1.1.100
1.1.1.103
1.1.1.107
1.1.1.118
1.1.1.126
1.1.1.132
1.1.1.133
1.1.1.138
1.1.1.141
1.1.1.146
1.1.1.153
1.1.1.158
1.1.1.159
1.1.1.169
1.1.1.184
1.1.1.188
1.1.1.189
1.1.1.195
1.1.1.203
1.1.1.204
1.1.1.205
1.1.1.209
1.1.1.213
1.1.1.218
1.1.1.219
1.1.1.236
1.1.1.248
1.1.1.252
1.1.1.262
1.1.1.263
1.1.1.267 *
1.1.1.268
1.1.1.272
1.1.1.274
1.1.1.284
1.1.1.289
1.1.1.290
1.1.2.-
1.1.3.-
1.1.5.-
1.1.99.-
1.2.-.-
1.3.-.-
1.4.-.-
1.5.-.-
1.6.-.-
1.7.-.-
1.8.-.-
1.9.-.-
1.10.-.-
1.11.-.-
1.12.-.-
1.13.-.-
1.14.-.-
1.15.-.-
1.16.-.-
1.17.-.-
1.18.-.-
1.21.-.-
1.97.-.-
2.- Transferases
3.- Hydrolases
4.- Lyases
5.- Isomerases
6.- Ligases
Unclassified Enzymes
Binding
Folding Proteins
Immunological Proteins
Mobility/Motility
Other
Toxins/Viral Proteins
Transcription/Translation
Transport
Cell Cycle
Signal Hormone
Structural
PDB Protein Homology Class
1.1.1.267
Families belonging to this class:
90% Homology Family
Leader:
1Q0H
CRYSTAL STRUCTURE OF SELENOMETHIONINE-LABELLED
DXR IN COMPLE FOSMIDOMYCIN
PDB id
Binding data
Representative ligand
1Q0H
Ki ~ 21.0 nM
FOM
1JVS
NDP
1ONP
FOM
1Q0Q
NDP
1T1R
ic50 = 4.0 uM
IMB
1T1S
ic50 = 7.0 uM
CBQ
2EGH
Ki = 38.0 nM
FOM
3ANL
ic50 = 4.6 uM
SYC
3ANM
ic50 = 0.84 uM
SYD
3ANN
ic50 = 15.9 uM
SYE
3R0I
ic50 = 0.12 uM
C0K
90% Homology Family
Leader:
2JCX
X-RAY STRUCTURE OF MUTANT 1-DEOXY-D-XYLULOSE
5-PHOSPHATE REDUCTOISOMERASE, DXR, RV2870C, FROM
MYCOBACTERIUM T UBERCULOSIS, IN COMPLEX
WITH FOSMIDOMYCIN AND NADPH
PDB id
Binding data
Representative ligand
2JCX
ic50 = 80.0 nM
FOM
2JCV
ic50 = 80.0 nM
FOM
2JD0
NDP
2JD1
NDP
2Y1D
34F
2Y1F
ic50 = 15.0 uM
34F
2Y1G
ic50 = 0.7 uM
FM5
90% Homology Family
Leader:
3A06
CRYSTAL STRUCTURE OF DXR FROM THERMOOGA MARITIA
, IN COMPLEX FOSMIDOMYCIN AND NADPH
PDB id
Binding data
Representative ligand
3A06
ic50 ~ 100.0 nM
FOM
3A14
NDP
