DIHYDROPYRIMIDINE DEHYDROGENASE (DPD) FROM PIG, TERNARY COMPLEX WITH NADPH AND 5-IODOURACIL
PDB id Source Resolution
1GTH SUS SCROFA 2.25 angstroms
Ligand Information
Ligand Validity Binding
Data		 Ligand
Warnings		 Eolus Viewer
(click picture
to launch)		 Chemaxon
Viewer		 Molecular
Weight
(Da)		 Formula SMILES
URA Valid submit data   launch gocavviewer-lite   112.087
C4 H4 N2 O2
 C1=CNC(=O)NC1=O
IUR Valid submit data   launch gocavviewer-lite   237.983
C4 H3 I N2 O2
 C1=C(C(=O)NC(=O)N1)I
FMN Valid submit data   launch gocavviewer-lite   456.344
C17 H21 N4 O9 P
 Cc1cc2c(cc1C)N(C3=NC(=O)NC(=O)C3=N2)C[C@@H]([C@@H]([C@@H](COP(=O)(O)O)O)O)O
FAD Valid submit data   launch gocavviewer-lite   785.55
C27 H33 N9 O15 P2
 Cc1cc2c(cc1C)N(C3=NC(=O)NC(=O)C3=N2)C[C@@H]([C@@H]([C@@H](CO[P@@](=O)(O)O[P@](=O)(O)OC[C@@H]4[C@H]([C@H]([C@@H](O4)n5cnc6c5ncnc6N)O)O)O)O)O
NDP Valid submit data   launch gocavviewer-lite   745.421
C21 H30 N7 O17 P3
 c1nc(c2c(n1)n(cn2)[C@H]3[C@@H]([C@@H]([C@H](O3)CO[P@](=O)(O)O[P@@](=O)(O)OC[C@@H]4[C@H]([C@H]([C@@H](O4)N5C=CCC(=C5)C(=O)N)O)O)O)OP(=O)(O)O)N
IDH Valid submit data   launch gocavviewer-lite   239.999
C4 H5 I N2 O2
 C1[C@@H](C(=O)NC(=O)N1)I

CRYSTAL STRUCTURE OF THE PRODUCTIVE TERNARY COMPLEX OF DIHYDROPYRIMIDINE DEHYDROGENASE WITH NADPH AND 5-IODOURACIL. IMPLICATIONS FOR MECHANISM OF INHIBITION AND ELECTRON TRANSFER J.BIOL.CHEM. V. 277 13155 2002

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90% Homology Family

The Class containing this family consists of a total of 1 families.
Leader:    1GTE
DIHYDROPYRIMIDINE DEHYDROGENASE (DPD) FROM PIG
, BINARY COMPLEX WITH 5-IODOURACIL
PDB id Binding data Representative ligand
1GTE   IUR
1GTH   URA
1H7W   FMN
1H7X   URF