DIHYDROPYRIMIDINE DEHYDROGENASE (DPD) FROM PIG, TERNARY COMPLEX OF A MUTANT ENZYME (C671A), NADPH AND 5 -FLUOROURACIL
PDB id Source Resolution
1H7X SUS SCROFA 2.01 angstroms
Ligand Information
Ligand Validity Binding
Data		 Ligand
Warnings		 Eolus Viewer
(click picture
to launch)		 Chemaxon
Viewer		 Molecular
Weight
(Da)		 Formula SMILES
URF Valid submit data   launch gocavviewer-lite   130.077
C4 H3 F N2 O2
 C1=C(C(=O)NC(=O)N1)F
FMN Valid submit data   launch gocavviewer-lite   456.344
C17 H21 N4 O9 P
 Cc1cc2c(cc1C)N(C3=NC(=O)NC(=O)C3=N2)C[C@@H]([C@@H]([C@@H](COP(=O)(O)O)O)O)O
FAD Valid submit data   launch gocavviewer-lite   785.55
C27 H33 N9 O15 P2
 Cc1cc2c(cc1C)N(C3=NC(=O)NC(=O)C3=N2)C[C@@H]([C@@H]([C@@H](CO[P@@](=O)(O)O[P@](=O)(O)OC[C@@H]4[C@H]([C@H]([C@@H](O4)n5cnc6c5ncnc6N)O)O)O)O)O
NDP Valid submit data   launch gocavviewer-lite   745.421
C21 H30 N7 O17 P3
 c1nc(c2c(n1)n(cn2)[C@H]3[C@@H]([C@@H]([C@H](O3)CO[P@](=O)(O)O[P@@](=O)(O)OC[C@@H]4[C@H]([C@H]([C@@H](O4)N5C=CCC(=C5)C(=O)N)O)O)O)OP(=O)(O)O)N

CRYSTAL STRUCTURE OF DIHYDROPYRIMIDINE DEHYDROGENASE, A MAJOR DETERMINANT OF THE PHARMACOKINETICS OF THE ANTI-CANCER DRUG 5-FLUOROURACIL EMBO J. V. 20 650 2001

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90% Homology Family

The Class containing this family consists of a total of 1 families.
Leader:    1GTE
DIHYDROPYRIMIDINE DEHYDROGENASE (DPD) FROM PIG
, BINARY COMPLEX WITH 5-IODOURACIL
PDB id Binding data Representative ligand
1GTE   IUR
1GTH   URA
1H7W   FMN
1H7X   URF