CRYSTAL STRUCTURE OF HUMAN NAD[P]H-QUINONE OXIDOREDUCTASE CO WITH 2,3,5,6,TETRAMETHYL-P-BENZOQUINONE (DUROQUINONE) AT2 .5 ANGSTROM RESOLUTION
PDB id Source Resolution
1DXO HOMO SAPIENS 2.5 angstroms
Ligand Information
Ligand Validity Binding
Data		 Ligand
Warnings		 Eolus Viewer
(click picture
to launch)		 Chemaxon
Viewer		 Molecular
Weight
(Da)		 Formula SMILES
FAD Valid submit data   launch gocavviewer-lite   785.55
C27 H33 N9 O15 P2
 Cc1cc2c(cc1C)N(C3=NC(=O)NC(=O)C3=N2)C[C@@H]([C@@H]([C@@H](CO[P@@](=O)(O)O[P@](=O)(O)OC[C@@H]4[C@H]([C@H]([C@@H](O4)n5cnc6c5ncnc6N)O)O)O)O)O
DQN Valid submit data   launch gocavviewer-lite   164.201
C10 H12 O2
 CC1=C(C(=O)C(=C(C1=O)C)C)C

STRUCTURES OF RECOMBINANT MOUSE AND HUMAN NAD(P)H:QUINONE OXIDOREDUCTASES:SPECIES COMPARISON AND STRUCTURAL CHANGES WITH SUBSTRATE BINDING AND RELEASE PROC.NATL.ACAD.SCI.USA V. 97 3177 2000

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90% Homology Family

The Class containing this family consists of a total of 3 families.
Leader:    1KBQ
COMPLEX OF HUMAN NAD(P)H QUINONE OXIDOREDUCTASE
WITH 5- METHOXY-1,2-DIMETHYL-3-(4-NITROPHENOXYMETHYL
)INDOLE-4,7- D IONE (ES936)
PDB id Binding data Representative ligand
1KBQ Ki = 0.45 uM 936
1D4A   FAD
1DXO   FAD
1GG5   FAD
1H66   RH1
1H69   FAD
1KBO   340
1QBG   FAD
3JSX ic50 = 7.7 nM CC2