ATOMIC X-RAY STRUCTURE OF LIVER ALCOHOL DEHYDROGENASE CONTAINING A HYDROXIDE ADDUCT TO NADH
PDB id Source Resolution
1HET 1.15 angstroms
Ligand Information
Ligand Validity Binding
Data		 Ligand
Warnings		 Eolus Viewer
(click picture
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Viewer		 Molecular
Weight
(Da)		 Formula SMILES
NAD Valid submit data More atoms than expected were found for ligand in PDB. % Diff = 1.22727  launch gocavviewer-lite   663.425
C21 H27 N7 O14 P2
 c1cc(c[n+](c1)[C@H]2[C@@H]([C@@H]([C@H](O2)CO[P@@](=O)([O-])O[P@@](=O)(O)OC[C@@H]3[C@H]([C@H]([C@@H](O3)n4cnc5c4ncnc5N)O)O)O)O)C(=O)N
MPD Invalid            

ON THE ENZYMATIC ACTIVATION OF NADH J.BIOL.CHEM. V. 276 9316 2001

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90% Homology Family

The Class containing this family consists of a total of 14 families.
Leader:    2JHF
STRUCTURAL EVIDENCE FOR A LIGAND COORDINATION
SWITCH IN LIVER ALCOHOL DEHYDROGENASE
PDB id Binding data Representative ligand
2JHF Kd = 5.0 nM NAD
1A71   NAD
1AXE   NAD
1AXG   ETF
1BTO Ki = 0.31 uM SSB
1EE2   NAD
1HET   NAD
1HEU   NAD
1HF3   NAD
1HLD Ki = 3.0 uM PFB
1JU9 Ki = 1640.0 uM NAD
1LDE   FPI
1LDY   CXF
1MG0   DFB
1MGO Ki = 51.0 uM PFB
1N8K   NAJ-PZO
1N92 Ki = 0.02 uM NAJ-PYZ
1P1R Ki = 15.0 uM NMH
1QLH   NAD
1QV6   NAD
1QV7   NAD
2JHG   NAD-IBO
2OHX   NAD
2OXI   NAD
3BTO Ki = 0.72 uM SSB
3OQ6   NAJ