CRYSTAL STRUCTURE OF THE TRIMER NECK AND CARBOHYDRATE RECOGNITION DOMAIN OF HUMAN SURFACTANT PROTEIN D IN C OMPLEX WITH P-NITROPHENYL MALTOSIDE
PDB id Source Resolution
2GGX 1.9 angstroms
Ligand Information
Ligand Validity Binding
Data		 Ligand
Warnings		 Eolus Viewer
(click picture
to launch)		 Chemaxon
Viewer		 Molecular
Weight
(Da)		 Formula SMILES
NPJ Valid ic50 =  0.32 mM   launch gocavviewer-lite   463.39
C18 H25 N O13
 c1cc(ccc1[N+](=O)[O-])O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)O)O

CONTRIBUTIONS OF PHENYLALANINE 335 TO LIGAND RECOGNITION BY HUMAN SURFACTANT PROTEIN D: RING INTERACTIONS WITH SP-D LIGANDS J.BIOL.CHEM. V. 281 18008 2006

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90% Homology Family

The Class containing this family consists of a total of 507 families.
Leader:    2GGX
CRYSTAL STRUCTURE OF THE TRIMER NECK AND CARBOHYDRATE
RECOGNITION DOMAIN OF HUMAN SURFACTANT PROTEIN
D IN C OMPLEX WITH P-NITROPHENYL MALTOSIDE
PDB id Binding data Representative ligand
2GGX ic50 = 0.32 mM NPJ
2GGU ic50 = 0.94 mM MLR
2ORJ   BM3
2ORK ic50 = 1.4 mM IPD
2OS9   INS
2RIA ic50 = 2.7 mM 289
2RIC   GMH-GMH
2RID ic50 = 1.7 mM 291
2RIE   293
3G81   MMA
3G83   MAN-MAN
3G84   MAN-MAN