INOSINE MONOPHOSPHATE DEHYDROGENASE (IMPDH) FROM TRITRICHOMO WITH RVP BOUND
PDB id Source Resolution
1ME8 TRITRICHOMONAS FOETUS 1.9 angstroms
Ligand Information
Ligand Validity Binding
Data		 Ligand
Warnings		 Eolus Viewer
(click picture
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Viewer		 Molecular
Weight
(Da)		 Formula SMILES
RVP Valid Ki =  65.0 nM   launch gocavviewer-lite   324.185
C8 H13 N4 O8 P
 c1nc(nn1[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)O)O)O)C(=O)N

CRYSTAL STRUCTURE OF TRITRICHOMONAS FOETUS INOSINE MONOPHOSPHATE DEHYDROGENASE IN COMPLEX WITH THE INH RIBAVIRIN MONOPHOSPHATE REVEALS A CATALYSIS-DEPENDE ION-BINDING SITE J.BIOL.CHEM. V. 277 50654 2002

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90% Homology Family

The Class containing this family consists of a total of 3 families.
Leader:    1ME8
INOSINE MONOPHOSPHATE DEHYDROGENASE (IMPDH) FROM
TRITRICHOMO WITH RVP BOUND
PDB id Binding data Representative ligand
1ME8 Ki = 65.0 nM RVP
1ME7 Ki = 65.0 nM RVP
1ME9   IMP
1MEH   IMP
1MEI   XMP
1MEW   XMP