THE 2.3 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF THE HETERODIMER OF THE HUMAN PPARGAMMA AND RXRALPHA LIGAND B INDING DOMAINS RESPECTIVELY BOUND WITH GW409544 AND 9-CIS RE TINOIC ACID AND CO-ACTIVATOR PEPTIDES.
PDB id Source Resolution
1K74 HOMO SAPIENS 2.3 angstroms
Ligand Information
Ligand Validity Binding
Data		 Ligand
Warnings		 Eolus Viewer
(click picture
to launch)		 Chemaxon
Viewer		 Molecular
Weight
(Da)		 Formula SMILES
544 Valid submit data   launch gocavviewer-lite   510.58
C31 H30 N2 O5
 Cc1c(nc(o1)c2ccccc2)CCOc3ccc(cc3)C[C@@H](C(=O)O)N/C(=CC(=O)c4ccccc4)/C
REA Valid submit data   launch gocavviewer-lite   300.435
C20 H28 O2
 CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC(=O)O)C)C

STRUCTURAL DETERMINANTS OF LIGAND BINDING SELECTIVITY BETWEEN THE PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS. PROC.NATL.ACAD.SCI.USA V. 98 13919 2001

More Information
External References
PDB
Pubmed
Biounit Downloads
This PDB
This Family
This Class
Comma Separated Files
This PDB
This Family
This Class
Download BindingMOAD
90% Homology Family

The Class containing this family consists of a total of 161 families.
Leader:    1FM9
THE 2.1 ANGSTROM RESOLUTION CRYSTAL STRUCTURE
OF THE HETERODIMER OF THE HUMAN RXRALPHA AND
PPARGAMMA LIGAND B INDING DOMAINS RESPECTIVELY
BOUND WITH 9-CIS RETINOIC AC ID AND GI262570
AND CO-ACTIVATOR PEPTIDES.
PDB id Binding data Representative ligand
1FM9 Ki = 1.0 nM 570
1FM6   REA
1K74   544