A NEW CLASS OF VITAMIN D RECEPTOR LIGANDS THAT INDUCE STRUCTURAL REARRANGEMENT OF THE LIGAND-BINDING POCKET
PDB id Source Resolution
2ZXN 2.1 angstroms
Ligand Information
Ligand Validity Binding
Data		 Ligand
Warnings		 Eolus Viewer
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Viewer		 Molecular
Weight
(Da)		 Formula SMILES
JC1 Valid submit data   launch gocavviewer-lite   430.663
C28 H46 O3
 CCCC[C@@H](CCO)[C@H](C)[C@H]1CC[C@@H]2[C@@]1(CCC/C2=CC=C/3C[C@H](C[C@@H](C3=C)O)O)C

A NEW CLASS OF VITAMIN D ANALOGUES THAT INDUCE STRUCTURAL REARRANGEMENT OF THE LIGAND-BINDING POCKET OF THE RECEPTOR J.MED.CHEM. V. 52 1438 2009

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90% Homology Family

The Class containing this family consists of a total of 172 families.
Leader:    2ZMI
CRYSTAL STRUCTURE OF RAT VITAMIN D RECEPTOR BOUND
TO ADAMANTYL VITAMIN D ANALOGS: STRUCTURAL BASIS
FOR VITAMIN D RECEPTOR ANTAGONISM AND/OR PARTIAL AGONISM
PDB id Binding data Representative ligand
2ZMI ic50 = 3.0 nM TT2
2ZFX   YR3
2ZL9   VDA
2ZLA   VDB
2ZLC   VDX
2ZMH   NYA
2ZMJ ic50 = 30.0 nM MI4
2ZXN   JC1
3A2H   TEJ
3AFR   ICJ