MYCOBACTERIUM TUBERCULOSIS THYX-NADP COMPLEX
PDB id Source Resolution
2GQ2 2.1 angstroms
Ligand Information
Ligand Validity Binding
Data		 Ligand
Warnings		 Eolus Viewer
(click picture
to launch)		 Chemaxon
Viewer		 Molecular
Weight
(Da)		 Formula SMILES
K Invalid            
IOD Invalid            
GOL Invalid            
PGE Invalid            
NAP Valid submit data   launch gocavviewer-lite   743.405
C21 H28 N7 O17 P3
 c1cc(c[n+](c1)[C@H]2[C@@H]([C@@H]([C@H](O2)CO[P@@](=O)([O-])O[P@](=O)(O)OC[C@@H]3[C@H]([C@H]([C@@H](O3)n4cnc5c4ncnc5N)OP(=O)(O)O)O)O)O)C(=O)N

NADP+ EXPELS BOTH THE CO-FACTOR AND A SUBSTRATE ANA THE MYCOBACTERIUM TUBERCULOSIS THYX ACTIVE SITE: OPPORTUNITIES FOR ANTI-BACTERIAL DRUG DESIGN. J.MOL.BIOL. V. 360 1 2006

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90% Homology Family

The Class containing this family consists of a total of 3 families.
Leader:    2AF6
CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS
FLAVIN DEPEN THYMIDYLATE SYNTHASE (MTB THYX)
IN THE PRESENCE OF CO-FACTOS UBSTRATE ANALOG
5-BROMO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE (
PDB id Binding data Representative ligand
2AF6   FAD
2GQ2   NAP