LACTOBACILLUS CASEI Y261M IN COMPLEX WITH SUBSTRATE, DUMP
PDB id Source Resolution
2G8A 2.4 angstroms
Ligand Information
Ligand Validity Binding
Data		 Ligand
Warnings		 Eolus Viewer
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Viewer		 Molecular
Weight
(Da)		 Formula SMILES
UMP Valid submit data   launch gocavviewer-lite   308.182
C9 H13 N2 O8 P
 C1[C@@H]([C@H](O[C@H]1N2C=CC(=O)NC2=O)COP(=O)(O)O)O

THE ROLE OF PROTEIN DYNAMICS IN THYMIDYLATE SYNTHAS CATALYSIS: VARIANTS OF CONSERVED 2'-DEOXYURIDINE 5'-MONOPHOSPHATE (DUMP)-BINDING TYR-261 BIOCHEMISTRY V. 45 7415 2006

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90% Homology Family

The Class containing this family consists of a total of 6 families.
Leader:    2G86
L. CASEI THYMIDYLATE SYNTHASE Y261F IN COMPLEX
WITH SUBSTRAT
PDB id Binding data Representative ligand
2G86 Kd = 0.44 uM UMP
1BO7   U
1BO8   U
1BP0 Kd = 4.0 uM UMP
1BP6   UMP
1BPJ   UMP
1JMF Kd = 1.7 uM UMP
1JMG Kd = 0.85 uM UMP
1JMH   UMP
1JMI Kd = 0.87 uM UMP
1LCA   UMP
1LCB   TMP
1LCE   UMP
1NJA Kd = 0.49 uM DCM
1NJC Kd = 2.8 uM DCM
1NJD Kd = 2.7 uM UMP
1NJE Kd = 160.0 uM DCM
1TSL Ki = 0.7 uM A15
1TSX   UMP
1TSY Kd = 11.0 uM UMP
1TVU   UMP
1TVV   UMP
1TVW   UMP
1VZA   UMP
1VZB   UMP
1VZC   UFP
1VZD   UFP
1VZE   CB3
2G89   UMP
2G8A   UMP
2G8D   UMP