BIOSYNTHETIC THIOLASE FROM Z. RAMIGERA. COMPLEX OF THE OXIDISED ENZYME WITH COENZYME A.
PDB id Source Resolution
2VU0 1.87 angstroms
Ligand Information
Ligand Validity Binding
Data		 Ligand
Warnings		 Eolus Viewer
(click picture
to launch)		 Chemaxon
Viewer		 Molecular
Weight
(Da)		 Formula SMILES
COA Valid submit data   launch gocavviewer-lite   767.534
C21 H36 N7 O16 P3 S
 CC(C)(CO[P@](=O)(O)O[P@@](=O)(O)OC[C@@H]1[C@H]([C@H]([C@@H](O1)n2cnc3c2ncnc3N)O)OP(=O)(O)O)[C@H](C(=O)NCCC(=O)NCCS)O
GOL Invalid            
SO4 Invalid            

THE SULFUR ATOMS OF THE SUBSTRATE COA AND THE CATAL CYSTEINE ARE REQUIRED FOR A PRODUCTIVE MODE OF SUBS BINDING IN BACTERIAL BIOSYNTHETIC THIOLASE, A THIOESTER-DEPENDENT ENZYME. FEBS J. V. 275 6136 2008

More Information
External References
PDB
Pubmed
Biounit Downloads
This PDB
This Family
This Class
Comma Separated Files
This PDB
This Family
This Class
Download BindingMOAD
90% Homology Family

The Class containing this family consists of a total of 3 families.
Leader:    2WL5
BIOSYNTHETIC THIOLASE FROM Z. RAMIGERA. COMPLEX
OF THE H348N MUTANT WITH COENZYME A.
PDB id Binding data Representative ligand
2WL5 Kd = 30.0 uM COA
1DLV   COA
1DM3   ACO
1M1O   CAA
1M3Z   ACO
1NL7   COA
1OU6   168
1QFL   COA
2VTZ Kd = 307.0 uM COA
2VU0   COA
2VU1   OPI
2WKT Kd = 49.0 uM COA
2WKV Kd = 128.0 uM COA
2WL4 Kd = 64.0 uM COA