HUMAN LIVER GLYCOGEN PHOSPHORYLASE A COMPLEXED WITH GLCNAC A 700
PDB id Source Resolution
1EXV HOMO SAPIENS 2.4 angstroms
Ligand Information
Ligand Validity Binding
Data		 Ligand
Warnings		 Eolus Viewer
(click picture
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Viewer		 Molecular
Weight
(Da)		 Formula SMILES
NBG Valid submit data   launch gocavviewer-lite   221.208
C8 H15 N O6
 CC(=O)N[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O
700 Valid ic50 =  45.0 nM   launch gocavviewer-lite   425.865
C22 H20 Cl N3 O4
 c1ccc(cc1)C[C@@H](C(=O)N2CC(C2)C(=O)O)NC(=O)c3cc4cc(ccc4[nH]3)Cl
MPD Invalid            
PLP Invalid            

HUMAN LIVER GLYCOGEN PHOSPHORYLASE INHIBITORS BIND ALLOSTERIC SITE. CHEM.BIOL. V. 7 677 2000

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90% Homology Family

The Class containing this family consists of a total of 3 families.
Leader:    1EM6
HUMAN LIVER GLYCOGEN PHOSPHORYLASE A COMPLEXED
WITH GLCNAC A 423
PDB id Binding data Representative ligand
1EM6 ic50 = 6.0 nM CP4
1EXV ic50 = 45.0 nM 700
1FA9   GLC
1FC0   NBG
1L5Q ic50 = 0.145 uM 700
1L5R Kd = 17.0 uM RBF
1L5S Kd = 550.0 uM URC
1L7X Kd = 92.0 uM CFF
1XOI ic50 = 0.057 uM 288
2ATI ic50 = 23.0 nM IHU
2ZB2 ic50 = 0.9 uM A46
3CEM Kd = 24.0 nM AVD
3DDS ic50 = 506.0 nM 26B
3DDW ic50 = 1067.0 nM 055