CRYSTAL STRUCTURE OF HUMAN FPPS IN COMPLEX WITH ZOLEDRONATE
PDB id Source Resolution
2F9K 2.06 angstroms
Ligand Information
Ligand Validity Binding
Data		 Ligand
Warnings		 Eolus Viewer
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to launch)		 Chemaxon
Viewer		 Molecular
Weight
(Da)		 Formula SMILES
ZOL Valid submit data   launch gocavviewer-lite   272.09
C5 H10 N2 O7 P2
 c1cn(cn1)CC(O)(P(=O)(O)O)P(=O)(O)O
PO4 Invalid            

STRUCTURAL BASIS FOR THE EXCEPTIONAL IN VIVO EFFICA BISPHOSPHONATE DRUGS. CHEMMEDCHEM V. 1 267 2006

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90% Homology Family

The Class containing this family consists of a total of 4 families.
Leader:    3N6K
HUMAN FPPS COMPLEX WITH NOV_823
PDB id Binding data Representative ligand
3N6K ic50 = 0.2 uM BFH
1YQ7   RIS
1YV5   RIS
1ZW5   IPR
2F8C   ZOL
2F92   AHD
2F94   BFQ
2F9K   ZOL
2OPM   NI9
3N1V ic50 > 500.0 uM 3N1
3N45   3N3
3N46   ZOL
3N49 ic50 = 7.0 uM 3N4
3N5H ic50 = 2.0 uM GO0
3N5J ic50 = 8.0 uM GO1