S. CEREVISIAE GERANYLGERANYL PYROPHOSPHATE SYNTHASE IN COMPL BPH-806
PDB id Source Resolution
2Z78 2.1 angstroms
Ligand Information
Ligand Validity Binding
Data		 Ligand
Warnings		 Eolus Viewer
(click picture
to launch)		 Chemaxon
Viewer		 Molecular
Weight
(Da)		 Formula SMILES
H86 Valid submit data   launch gocavviewer-lite   536.463
C23 H34 F2 N O7 P2
 CCCCCCCCCCOc1cc(c[n+](c1)CC(P(=O)(O)O)P(=O)(O)O)c2cc(cc(c2)F)F

INHIBITION OF GERANYLGERANYL DIPHOSPHATE SYNTHASE B BISPHOSPHONATES: A CRYSTALLOGRAPHIC AND COMPUTATION INVESTIGATION J.MED.CHEM. V. 51 5594 2008

More Information
External References
PDB
Pubmed
Biounit Downloads
This PDB
This Family
This Class
Comma Separated Files
This PDB
This Family
This Class
Download BindingMOAD
90% Homology Family

The Class containing this family consists of a total of 1 families.
Leader:    2Z7I
S. CEREVISIAE GERANYLGERANYL PYROPHOSPHATE SYNTHASE
IN COMPL INHIBITOR BPH-742
PDB id Binding data Representative ligand
2Z7I ic50 = 0.1 uM 742
2E8T   IPE
2E8U   IPE
2E8V   GRG
2E8W   IPE
2E8X   GPP
2E91   ZOL
2E92   M0N
2E93   B29
2E94   364
2Z4V   GRG
2Z4W ic50 = 0.98 uM 749
2Z4X ic50 = 0.71 uM 252
2Z4Y ic50 = 0.71 uM 252
2Z4Z ic50 = 1.86 uM SC0
2Z50 ic50 = 11.2 uM 028
2Z52 ic50 = 2.69 uM H23
2Z78   H86
2Z7H Ki = 115.0 nM GG3
2ZEU   B71
2ZEV   IPE