Receptor
PDB id Resolution Class Description Source Keywords
11BA 2.06 Å EC: 3.1.27.5 BINDING OF A SUBSTRATE ANALOGUE TO A DOMAIN SWAPPING PROTEIN COMPLEX OF BOVINE SEMINAL RIBONUCLEASE WITH URIDYLYL-2',5'- BOS TAURUS HYDROLASE PHOSPHORIC DIESTER RNA 2-prime -5-prime -DINUCLEOTIDE
Ref.: BINDING OF A SUBSTRATE ANALOG TO A DOMAIN SWAPPING X-RAY STRUCTURE OF THE COMPLEX OF BOVINE SEMINAL RIBONUCLEASE WITH URIDYLYL(2',5')ADENOSINE. PROTEIN SCI. V. 7 1691 1998
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
SO4 A:127;
B:128;
B:129;
Invalid;
Invalid;
Invalid;
none;
none;
none;
submit data
96.063 O4 S [O-]S...
UPA A:125;
B:126;
Valid;
Valid;
none;
none;
submit data
573.407 C19 H24 N7 O12 P c1nc(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3DJV 1.6 Å EC: 3.1.27.5 BOVINE SEMINAL RIBONUCLEASE- CYTIDINE 3' PHOSPHATE COMPLEX BOS TAURUS RIBONUCLEASE HYDROLASE ALLOSTERIC ENZYME ENDONUCLEASE NUSECRETED
Ref.: MAPPING THE RIBONUCLEOLYTIC ACTIVE SITE OF BOVINE S RIBONUCLEASE. THE BINDING OF PYRIMIDINYL PHOSPHONUC INHIBITORS EUR.J.MED.CHEM. V. 44 4496 2009
Members (10)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 5 families.
1 3DJV Ki = 27.9 uM C3P C9 H14 N3 O8 P C1=CN(C(=O....
2 1R5C - CPA C19 H25 N8 O9 P c1nc(c2c(n....
3 11BA - UPA C19 H24 N7 O12 P c1nc(c2c(n....
4 1TQ9 - CPA C19 H25 N8 O9 P c1nc(c2c(n....
5 3DJQ Ki = 1046.4 uM UDP C9 H14 N2 O12 P2 C1=CN(C(=O....
6 3DJP Ki = 63.2 uM UA3 C9 H13 N2 O9 P C1=CN(C(=O....
7 3DJX Ki = 1557 uM C5P C9 H14 N3 O8 P C1=CN(C(=O....
8 11BG - U2G C19 H24 N7 O13 P c1nc2c(n1[....
9 3DJO Ki = 40.8 uM U2P C9 H13 N2 O9 P C1=CN(C(=O....
10 1N3Z - U3P C9 H13 N2 O9 P C1=CN(C(=O....
70% Homology Family (67)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 1Z6D Ki = 4.6 mM IMP C10 H13 N4 O8 P c1nc2c(n1[....
2 1O0H Ki = 1.2 uM ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
3 1W4O Ki = 5.85 uM UA3 C9 H13 N2 O9 P C1=CN(C(=O....
4 1RNN - C5P C9 H14 N3 O8 P C1=CN(C(=O....
5 1JVU - C2P C9 H14 N3 O8 P C1=CN(C(=O....
6 3D7B Ki = 203 uM U4S C13 H19 N3 O5 C1CCN(C1)C....
7 3FL1 - CGP C19 H25 N8 O10 P c1nc2c(n1[....
8 2XOG Ki = 370 uM SFB C20 H28 N8 O11 S c1nc(c2c(n....
9 3D6Q Ki = 172 uM U3S C14 H21 N3 O5 C1CCN(CC1)....
10 3JW1 - U5P C9 H13 N2 O9 P C1=CN(C(=O....
11 3EV6 - RSF C6 H10 O3 C1CO[C@H]2....
12 2W5I Ki = 4.7 uM ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
13 3D8Y Ki = 396 uM T3S C15 H23 N3 O4 CC1=CN(C(=....
14 1W4P Ki = 18 uM UM3 C9 H13 N2 O8 P C1[C@@H]([....
15 3D6O Ki = 77 uM U1S C17 H25 N3 O7 CCOC(=O)C1....
16 1AFL Ki = 520 nM ATR C10 H16 N5 O13 P3 c1nc(c2c(n....
17 3EV3 - TBU C4 H10 O CC(C)(C)O
18 3LXO Kd = 15 uM T3P C10 H15 N2 O8 P CC1=CN(C(=....
19 3RID - CGP C19 H25 N8 O10 P c1nc2c(n1[....
20 1O0O Ki = 8 uM A2P C10 H15 N5 O10 P2 c1nc(c2c(n....
21 1RPF - C3P C9 H14 N3 O8 P C1=CN(C(=O....
22 3D6P Ki = 179 uM U2S C13 H19 N3 O6 C1COCCN1C[....
23 1RPG - CPA C19 H25 N8 O9 P c1nc(c2c(n....
24 4G8V Ki = 1.6 uM 0EY C12 H15 N5 O6 c1c(nnn1[C....
25 1RNC - 5GP C10 H14 N5 O8 P c1nc2c(n1[....
26 1WBU - WBU C4 H5 N3 O2 C1=C(C(=O)....
27 1ROB - C2P C9 H14 N3 O8 P C1=CN(C(=O....
28 1W4Q Ki = 5.5 uM UMF C9 H12 F N2 O8 P C1=CN(C(=O....
29 4G8Y Ki = 25.8 uM 0FT C13 H17 N5 O6 CC1=CN(C(=....
30 1O0F Ki = 5 uM A3P C10 H15 N5 O10 P2 c1nc(c2c(n....
31 1JN4 Ki = 11.3 uM 139 C19 H25 N7 O14 P2 c1nc(c2c(n....
32 1O0N Ki = 82 uM U3P C9 H13 N2 O9 P C1=CN(C(=O....
33 3EV4 - ETF C2 H3 F3 O C(C(F)(F)F....
34 1RCA - CGP C19 H25 N8 O10 P c1nc2c(n1[....
35 1AFK Ki = 240 nM PAP C10 H16 N5 O13 P3 c1nc(c2c(n....
36 1RND - DGP C10 H14 N5 O7 P c1nc2c(n1[....
37 2XOI Ki = 370 uM SFB C20 H28 N8 O11 S c1nc(c2c(n....
38 1EOW - U2G C19 H24 N7 O13 P c1nc2c(n1[....
39 4RSK Kd = 47.4 uM U3P C9 H13 N2 O9 P C1=CN(C(=O....
40 1RCN - DA DT DA DA n/a n/a
41 1RNM - C5P C9 H14 N3 O8 P C1=CN(C(=O....
42 2W5K Ki = 12 uM NDP C21 H30 N7 O17 P3 c1nc(c2c(n....
43 2G8R Ki = 103 uM N3E C15 H21 N3 O7 C1CN(CCC1C....
44 1U1B Kd = 16 nM PAX C20 H27 N7 O20 P4 CC1=CN(C(=....
45 1QHC Ki = 27 nM PUA C19 H27 N7 O20 P4 c1nc(c2c(n....
46 3FL0 - CGP C19 H25 N8 O10 P c1nc2c(n1[....
47 1F0V - DC DG n/a n/a
48 2W5L Ki = 63 uM NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
49 1RUV - UVC C9 H12 N2 O9 V C1=CN(C(=O....
50 1O0M Ki = 7.1 uM U2P C9 H13 N2 O9 P C1=CN(C(=O....
51 2QCA - DGP C10 H14 N5 O7 P c1nc2c(n1[....
52 1Z6S Ki = 63 uM AMP C10 H14 N5 O7 P c1nc(c2c(n....
53 3EV5 - TMO C3 H9 N O C[N+](C)(C....
54 4G90 Ki = 30.8 uM 0G0 C12 H14 F N5 O6 c1c(nnn1[C....
55 2W5G Ki = 0.86 uM ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
56 3D8Z Ki = 423 uM TXS C14 H21 N3 O4 CC1=CN(C(=....
57 1EOS - U2G C19 H24 N7 O13 P c1nc2c(n1[....
58 3DJV Ki = 27.9 uM C3P C9 H14 N3 O8 P C1=CN(C(=O....
59 1R5C - CPA C19 H25 N8 O9 P c1nc(c2c(n....
60 11BA - UPA C19 H24 N7 O12 P c1nc(c2c(n....
61 1TQ9 - CPA C19 H25 N8 O9 P c1nc(c2c(n....
62 3DJQ Ki = 1046.4 uM UDP C9 H14 N2 O12 P2 C1=CN(C(=O....
63 3DJP Ki = 63.2 uM UA3 C9 H13 N2 O9 P C1=CN(C(=O....
64 3DJX Ki = 1557 uM C5P C9 H14 N3 O8 P C1=CN(C(=O....
65 11BG - U2G C19 H24 N7 O13 P c1nc2c(n1[....
66 3DJO Ki = 40.8 uM U2P C9 H13 N2 O9 P C1=CN(C(=O....
67 1N3Z - U3P C9 H13 N2 O9 P C1=CN(C(=O....
50% Homology Family (68)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 1Z6D Ki = 4.6 mM IMP C10 H13 N4 O8 P c1nc2c(n1[....
2 1O0H Ki = 1.2 uM ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
3 1W4O Ki = 5.85 uM UA3 C9 H13 N2 O9 P C1=CN(C(=O....
4 1RNN - C5P C9 H14 N3 O8 P C1=CN(C(=O....
5 1JVU - C2P C9 H14 N3 O8 P C1=CN(C(=O....
6 3D7B Ki = 203 uM U4S C13 H19 N3 O5 C1CCN(C1)C....
7 3FL1 - CGP C19 H25 N8 O10 P c1nc2c(n1[....
8 2XOG Ki = 370 uM SFB C20 H28 N8 O11 S c1nc(c2c(n....
9 3D6Q Ki = 172 uM U3S C14 H21 N3 O5 C1CCN(CC1)....
10 3JW1 - U5P C9 H13 N2 O9 P C1=CN(C(=O....
11 3EV6 - RSF C6 H10 O3 C1CO[C@H]2....
12 2W5I Ki = 4.7 uM ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
13 3D8Y Ki = 396 uM T3S C15 H23 N3 O4 CC1=CN(C(=....
14 1W4P Ki = 18 uM UM3 C9 H13 N2 O8 P C1[C@@H]([....
15 3D6O Ki = 77 uM U1S C17 H25 N3 O7 CCOC(=O)C1....
16 1AFL Ki = 520 nM ATR C10 H16 N5 O13 P3 c1nc(c2c(n....
17 3EV3 - TBU C4 H10 O CC(C)(C)O
18 3LXO Kd = 15 uM T3P C10 H15 N2 O8 P CC1=CN(C(=....
19 3RID - CGP C19 H25 N8 O10 P c1nc2c(n1[....
20 1O0O Ki = 8 uM A2P C10 H15 N5 O10 P2 c1nc(c2c(n....
21 1RPF - C3P C9 H14 N3 O8 P C1=CN(C(=O....
22 3D6P Ki = 179 uM U2S C13 H19 N3 O6 C1COCCN1C[....
23 1RPG - CPA C19 H25 N8 O9 P c1nc(c2c(n....
24 4G8V Ki = 1.6 uM 0EY C12 H15 N5 O6 c1c(nnn1[C....
25 1RNC - 5GP C10 H14 N5 O8 P c1nc2c(n1[....
26 1WBU - WBU C4 H5 N3 O2 C1=C(C(=O)....
27 1ROB - C2P C9 H14 N3 O8 P C1=CN(C(=O....
28 1W4Q Ki = 5.5 uM UMF C9 H12 F N2 O8 P C1=CN(C(=O....
29 4G8Y Ki = 25.8 uM 0FT C13 H17 N5 O6 CC1=CN(C(=....
30 1O0F Ki = 5 uM A3P C10 H15 N5 O10 P2 c1nc(c2c(n....
31 1JN4 Ki = 11.3 uM 139 C19 H25 N7 O14 P2 c1nc(c2c(n....
32 1O0N Ki = 82 uM U3P C9 H13 N2 O9 P C1=CN(C(=O....
33 3EV4 - ETF C2 H3 F3 O C(C(F)(F)F....
34 1RCA - CGP C19 H25 N8 O10 P c1nc2c(n1[....
35 1AFK Ki = 240 nM PAP C10 H16 N5 O13 P3 c1nc(c2c(n....
36 1RND - DGP C10 H14 N5 O7 P c1nc2c(n1[....
37 2XOI Ki = 370 uM SFB C20 H28 N8 O11 S c1nc(c2c(n....
38 1EOW - U2G C19 H24 N7 O13 P c1nc2c(n1[....
39 4RSK Kd = 47.4 uM U3P C9 H13 N2 O9 P C1=CN(C(=O....
40 1RCN - DA DT DA DA n/a n/a
41 1RNM - C5P C9 H14 N3 O8 P C1=CN(C(=O....
42 2W5K Ki = 12 uM NDP C21 H30 N7 O17 P3 c1nc(c2c(n....
43 2G8R Ki = 103 uM N3E C15 H21 N3 O7 C1CN(CCC1C....
44 1U1B Kd = 16 nM PAX C20 H27 N7 O20 P4 CC1=CN(C(=....
45 1QHC Ki = 27 nM PUA C19 H27 N7 O20 P4 c1nc(c2c(n....
46 3FL0 - CGP C19 H25 N8 O10 P c1nc2c(n1[....
47 1F0V - DC DG n/a n/a
48 2W5L Ki = 63 uM NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
49 1RUV - UVC C9 H12 N2 O9 V C1=CN(C(=O....
50 1O0M Ki = 7.1 uM U2P C9 H13 N2 O9 P C1=CN(C(=O....
51 2QCA - DGP C10 H14 N5 O7 P c1nc2c(n1[....
52 1Z6S Ki = 63 uM AMP C10 H14 N5 O7 P c1nc(c2c(n....
53 3EV5 - TMO C3 H9 N O C[N+](C)(C....
54 4G90 Ki = 30.8 uM 0G0 C12 H14 F N5 O6 c1c(nnn1[C....
55 2W5G Ki = 0.86 uM ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
56 3D8Z Ki = 423 uM TXS C14 H21 N3 O4 CC1=CN(C(=....
57 1EOS - U2G C19 H24 N7 O13 P c1nc2c(n1[....
58 2RNF - UM3 C9 H13 N2 O8 P C1[C@@H]([....
59 3DJV Ki = 27.9 uM C3P C9 H14 N3 O8 P C1=CN(C(=O....
60 1R5C - CPA C19 H25 N8 O9 P c1nc(c2c(n....
61 11BA - UPA C19 H24 N7 O12 P c1nc(c2c(n....
62 1TQ9 - CPA C19 H25 N8 O9 P c1nc(c2c(n....
63 3DJQ Ki = 1046.4 uM UDP C9 H14 N2 O12 P2 C1=CN(C(=O....
64 3DJP Ki = 63.2 uM UA3 C9 H13 N2 O9 P C1=CN(C(=O....
65 3DJX Ki = 1557 uM C5P C9 H14 N3 O8 P C1=CN(C(=O....
66 11BG - U2G C19 H24 N7 O13 P c1nc2c(n1[....
67 3DJO Ki = 40.8 uM U2P C9 H13 N2 O9 P C1=CN(C(=O....
68 1N3Z - U3P C9 H13 N2 O9 P C1=CN(C(=O....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: UPA; Similar ligands found: 203
No: Ligand ECFP6 Tc MDL keys Tc
1 UPA 1 1
2 UP5 0.711712 0.986667
3 4TC 0.699115 0.961039
4 U2G 0.686957 0.925
5 APU 0.678261 0.960526
6 139 0.652542 0.961538
7 25A 0.626168 0.907895
8 A U 0.608333 0.960526
9 25L 0.59292 0.921053
10 A2D 0.58 0.933333
11 ADP 0.578431 0.907895
12 A22 0.572727 0.921053
13 PRX 0.571429 0.8375
14 BA3 0.568627 0.933333
15 U G A 0.568345 0.901235
16 AGS 0.566038 0.8625
17 SAP 0.566038 0.8625
18 A 0.565657 0.881579
19 AMP 0.565657 0.881579
20 B4P 0.563107 0.933333
21 AP5 0.563107 0.933333
22 ADQ 0.5625 0.934211
23 ATP 0.561905 0.907895
24 5FA 0.556604 0.907895
25 AQP 0.556604 0.907895
26 ADX 0.552381 0.821429
27 M33 0.552381 0.896104
28 CA0 0.552381 0.909091
29 ACP 0.54717 0.884615
30 50T 0.54717 0.871795
31 ATF 0.545455 0.873418
32 SRA 0.544554 0.8375
33 CG2 0.543307 0.925
34 APR 0.542056 0.907895
35 AR6 0.542056 0.907895
36 ANP 0.541284 0.884615
37 ACQ 0.541284 0.884615
38 AD9 0.537037 0.884615
39 ABM 0.533981 0.858974
40 G3A 0.528926 0.8875
41 TAT 0.527273 0.873418
42 PUA 0.526316 0.924051
43 OAD 0.525862 0.909091
44 G5P 0.52459 0.8875
45 AMP MG 0.524272 0.835443
46 A12 0.52381 0.873418
47 AP2 0.52381 0.873418
48 5AL 0.522523 0.896104
49 APC 0.513761 0.873418
50 SRP 0.513274 0.897436
51 AU1 0.509259 0.884615
52 PAJ 0.508621 0.876543
53 A1R 0.508621 0.875
54 4AD 0.508621 0.886076
55 1ZZ 0.504202 0.811765
56 BIS 0.504202 0.851852
57 3OD 0.504202 0.909091
58 T5A 0.5 0.902439
59 ADP BMA 0.5 0.909091
60 GTA 0.496 0.855422
61 PR8 0.495798 0.843373
62 AMO 0.495726 0.897436
63 ADV 0.495495 0.873418
64 RBY 0.495495 0.873418
65 ADP MG 0.495413 0.848101
66 PTJ 0.491667 0.841463
67 FYA 0.491667 0.871795
68 00A 0.491525 0.875
69 AHX 0.491525 0.8875
70 DLL 0.491525 0.921053
71 BEF ADP 0.490909 0.82716
72 ADP BEF 0.490909 0.82716
73 U2P 0.49 0.828947
74 SFB 0.488372 0.808989
75 A4P 0.484615 0.880952
76 TXD 0.484375 0.923077
77 NAI 0.484375 0.948052
78 LAD 0.483333 0.853659
79 ADP PO3 0.482143 0.881579
80 ATR 0.482143 0.881579
81 TXA 0.479339 0.897436
82 ME8 0.479339 0.811765
83 NB8 0.479339 0.864198
84 MAP 0.478632 0.8625
85 ATP MG 0.477876 0.848101
86 UPU 0.477477 0.866667
87 5AS 0.477064 0.755556
88 AP0 0.476923 0.911392
89 AFH 0.47619 0.876543
90 ANP MG 0.474138 0.839506
91 GAP 0.473684 0.884615
92 NAX 0.472868 0.9125
93 SON 0.472727 0.873418
94 A2R 0.470085 0.896104
95 A2P 0.46789 0.868421
96 FA5 0.467742 0.897436
97 YAP 0.467742 0.886076
98 G A A A 0.466667 0.864198
99 ADP ALF 0.465517 0.817073
100 ALF ADP 0.465517 0.817073
101 XAH 0.464 0.833333
102 NA7 0.46281 0.873418
103 ADP VO4 0.461538 0.871795
104 ADN 0.459184 0.813333
105 RAB 0.459184 0.813333
106 XYA 0.459184 0.813333
107 TYM 0.458015 0.897436
108 LAQ 0.457364 0.811765
109 PAP 0.45614 0.894737
110 GPG 0.455285 0.9
111 ADJ 0.455224 0.845238
112 A3P 0.454545 0.881579
113 YLP 0.453846 0.813953
114 DAL AMP 0.453782 0.871795
115 3AM 0.45283 0.868421
116 MYR AMP 0.451613 0.790698
117 NXX 0.450382 0.922078
118 DND 0.450382 0.922078
119 4TA 0.445255 0.86747
120 PPS 0.444444 0.8
121 ATP A A A 0.444444 0.894737
122 EAD 0.444444 0.9125
123 YLB 0.443609 0.813953
124 2AM 0.443396 0.881579
125 AOC 0.440367 0.792208
126 ODP 0.437956 0.924051
127 IOT 0.437037 0.804598
128 BTX 0.434783 0.813953
129 2A5 0.434783 0.860759
130 YLC 0.432836 0.855422
131 P1H 0.432432 0.890244
132 BT5 0.431655 0.804598
133 A4D 0.431373 0.789474
134 AR6 AR6 0.430769 0.883117
135 AYB 0.430657 0.804598
136 CNA 0.430657 0.922078
137 ITT 0.429825 0.857143
138 PUP 0.429752 0.797468
139 Z5A 0.427586 0.837209
140 G5A 0.42735 0.775281
141 NAJ PZO 0.425532 0.8875
142 COD 0.42446 0.806818
143 NAD 0.42446 0.921053
144 0WD 0.42446 0.935897
145 P5A 0.424 0.741935
146 V3L 0.423729 0.883117
147 NDP 0.423358 0.935897
148 YLA 0.423358 0.835294
149 5N5 0.421569 0.789474
150 TXP 0.42029 0.911392
151 7MD 0.419847 0.855422
152 YLY 0.41958 0.804598
153 A3D 0.41844 0.909091
154 OVE 0.418182 0.848101
155 UDP 0.418182 0.842105
156 TSB 0.418033 0.793103
157 5CA 0.418033 0.795455
158 5CD 0.417476 0.753247
159 UFM 0.416667 0.868421
160 AV2 0.416667 0.835443
161 3DH 0.416667 0.725
162 GDU 0.416667 0.868421
163 UPG 0.416667 0.868421
164 TAD 0.416667 0.853659
165 A5A 0.416667 0.781609
166 GUD 0.416667 0.868421
167 AMP DBH 0.415385 0.860759
168 NAQ 0.413793 0.864198
169 AHZ 0.413534 0.790698
170 SSA 0.413223 0.795455
171 NPW 0.413043 0.901235
172 FDA 0.411765 0.870588
173 NSS 0.41129 0.775281
174 LPA AMP 0.410448 0.790698
175 NZQ 0.410072 0.924051
176 54H 0.409836 0.764045
177 VMS 0.409836 0.764045
178 52H 0.409836 0.755556
179 6FA 0.409091 0.857143
180 6AD 0.408333 0.831325
181 NVA LMS 0.408 0.73913
182 NJP 0.407143 0.910256
183 UTP 0.40708 0.842105
184 NAE 0.406897 0.886076
185 UPF 0.406504 0.825
186 53H 0.406504 0.755556
187 U2F 0.406504 0.825
188 EP4 0.40566 0.707317
189 AF3 ADP 3PG 0.404412 0.809524
190 NDE 0.403974 0.897436
191 FAS 0.403846 0.86747
192 SFD 0.403846 0.75
193 FAD 0.403846 0.86747
194 MAO 0.403509 0.715909
195 U 0.401869 0.828947
196 U5P 0.401869 0.828947
197 M2T 0.401869 0.690476
198 DTA 0.401869 0.759494
199 DZD 0.401408 0.876543
200 ZID 0.401361 0.909091
201 DSZ 0.4 0.775281
202 LSS 0.4 0.73913
203 M24 0.4 0.843373
Similar Binding Sites
Pocket no: 1; Query (leader) PDB : 3DJV; Ligand: C3P; Similar sites found: 24
This union binding pocket (no: 1) in the query (biounit: 3djv.bio1) has 34 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc)
1 3DJV C3P 8.872e-20 1
2 1U1B PAX 1.123e-11 0.71543
3 2BZZ AP5 3.229e-07 0.46186
4 2RNF UM3 2.129e-09 0.42952
5 1M07 DC 2.211e-08 0.40848
6 2GMK AMP 3.296e-07 0.3975
7 2Q4G CIT 1.643e-05 0.32562
8 4MZQ 1VU 0.03012 0.31585
9 3P48 DUP 0.04429 0.30272
10 3UKR CKH 0.04306 0.29039
11 2A9W UMP 0.03825 0.28701
12 2HRL SIA 0.03836 0.28492
13 2WBV SIA 0.03074 0.28385
14 2Q2R BGC 0.0467 0.28357
15 2WBV SIA 0.04131 0.28304
16 4NS0 PIO 0.03772 0.27653
17 4X0M 3WA 0.04937 0.27604
18 2R5A MLZ 0.04 0.2751
19 2QLU ADE 0.047 0.27378
20 1JPA ANP 0.01072 0.27361
21 1WOG 16D 0.04242 0.27067
22 2RHI THR 0.04691 0.27051
23 1SS4 GSH 0.03719 0.25819
24 1XVB BBU 0.007607 0.25773
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