Receptor
PDB id Resolution Class Description Source Keywords
1A1N 2 Å NON-ENZYME: IMMUNE MHC CLASS I MOLECULE B*3501 COMPLEXED WITH PEPTIDE VPLRPMTY FROM THE NEF PROTEIN (75-82) OF HIV1 HOMO SAPIENS MAJOR HISTOCOMPATIBILITY ANTIGEN MHC HLA HLA-B3501 HIV NEF COMPLEX (ANTIGEN/PEPTIDE)
Ref.: AN ALTERED POSITION OF THE ALPHA 2 HELIX OF MHC CLASS I IS REVEALED BY THE CRYSTAL STRUCTURE OF HLA-B*3501. IMMUNITY V. 4 203 1996
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
VAL PRO LEU ARG PRO MET THR TYR C:1;
Valid;
none;
submit data
977.219 n/a S(CCC...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4O2C 1.8 Å NON-ENZYME: IMMUNE AN NT-ACETYLATED PEPTIDE COMPLEXED WITH HLA-B*3901 HOMO SAPIENS IG-LIKE IMMUNE SYSTEM
Ref.: N ALPHA-TERMINAL ACETYLATION FOR T CELL RECOGNITION MOLECULAR BASIS OF MHC CLASS I-RESTRICTED N ALPHA-ACETYLPEPTIDE PRESENTATION J.IMMUNOL. V. 192 5509 2014
Members (76)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 180 families.
1 2RFX - LEU SER SER PRO VAL THR LYS SER PHE n/a n/a
2 3KPN - GLU GLU TYR LEU GLN ALA PHE THR TYR n/a n/a
3 3X13 - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
4 3VRI - ARG VAL ALA GLN LEU GLU GLN VAL TYR ILE n/a n/a
5 3LKP - LEU PRO PHE ASP LYS SER THR ILE MET n/a n/a
6 3LV3 - SER ARG ARG TRP ARG ARG TRP ASN ARG n/a n/a
7 1A9E - LEU PRO PRO LEU ASP ILE THR PRO TYR n/a n/a
8 1UXW - ARG ARG ARG TRP ARG ARG LEU THR VAL n/a n/a
9 1W0W - ARG ARG LEU PRO ILE PHE SER ARG LEU n/a n/a
10 1XR8 - LEU GLU LYS ALA ARG GLY SER THR TYR n/a n/a
11 4G8I - LYS ARG TRP ILE ILE MET GLY LEU ASN LYS n/a n/a
12 1AGC - GLY GLY LYS LYS LYS TYR GLN LEU n/a n/a
13 1A1M - THR PRO TYR ASP ILE ASN GLN MET LEU n/a n/a
14 3SKO - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
15 3BXN - ILE ARG ALA ALA PRO PRO PRO LEU PHE n/a n/a
16 1A1O - LYS PRO ILE VAL GLN TYR ASP ASN PHE n/a n/a
17 2BVP - ILE SER PRO ARG THR LEU ASP ALA TRP n/a n/a
18 3DX7 - GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE n/a n/a
19 1M05 - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
20 1UXS - ARG ARG ARG TRP ARG ARG LEU THR VAL n/a n/a
21 2BSR - ARG ARG ILE TYR ASP LEU ILE GLU LEU n/a n/a
22 3VRJ - LEU THR THR LYS LEU THR ASN THR ASN ILE n/a n/a
23 2BST - SER ARG TYR TRP ALA ILE ARG THR ARG n/a n/a
24 3BP4 - ILE ARG ALA ALA PRO PRO PRO LEU PHE n/a n/a
25 3X12 - LEU SER SER PRO VAL THR LYS SER PHE n/a n/a
26 4O2C ic50 = 10 nM ACE SER HIS VAL ALA VAL GLU ASN ALA LEU n/a n/a
27 1AGB - GLY GLY ARG LYS LYS TYR LYS LEU n/a n/a
28 3LKQ - LEU PRO PHE ASP LYS THR THR ILE MET n/a n/a
29 2AXG - ALA PRO GLN PRO ALA PRO GLU ASN ALA TYR n/a n/a
30 1A1N - VAL PRO LEU ARG PRO MET THR TYR n/a n/a
31 1OGT - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
32 3KPO - GLU GLU TYR LEU LYS ALA TRP THR PHE n/a n/a
33 3DX6 - GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE n/a n/a
34 2A83 - ARG ARG ARG TRP HIS ARG TRP ARG LEU n/a n/a
35 3B6S - ARG ARG LYS TRP CIR ARG TRP HIS LEU n/a n/a
36 1JGD - ARG ARG LEU LEU ARG GLY HIS ASN GLN TYR n/a n/a
37 1AGF - GLY GLY LYS LYS ARG TYR LYS LEU n/a n/a
38 2CIK - LYS PRO ILE VAL VAL LEU HIS GLY TYR n/a n/a
39 3LKN - LEU PRO PHE GLU ARG ALA THR ILE MET n/a n/a
40 1HSA - ALA ARG ALA ALA ALA ALA ALA ALA ALA n/a n/a
41 1AGE - GLY GLY LYS LYS LYS TYR ARG LEU n/a n/a
42 2BSS - LYS ARG TRP ILE ILE LEU GLY LEU ASN LYS n/a n/a
43 4JQV - SER GLU LEU GLU ILE LYS ARG TYR n/a n/a
44 3C9N - VAL GLN GLN GLU SER SER PHE VAL MET n/a n/a
45 3X11 - LEU SER SER PRO VAL THR LYS SER PHE n/a n/a
46 1M6O - GLU GLU PHE GLY ARG ALA PHE SER PHE n/a n/a
47 3B3I - ARG ARG LYS TRP CIR ARG TRP HIS LEU n/a n/a
48 3DX8 - GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE n/a n/a
49 3KPL - GLU GLU TYR LEU GLN ALA PHE THR TYR n/a n/a
50 4G9D - LYS ARG TRP ILE ILE LEU GLY LEU ASN LYS n/a n/a
51 3LKR - LEU PRO PHE GLU ARG ALA THR VAL MET n/a n/a
52 3KPP - GLU GLU TYR LEU GLN ALA PHE THR TYR n/a n/a
53 1K5N - GLY ARG PHE ALA ALA ALA ILE ALA LYS n/a n/a
54 1OF2 - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
55 4O2E - SER HIS VAL ALA VAL GLU ASN ALA LEU n/a n/a
56 3BP7 - ILE ARG ALA ALA PRO PRO PRO LEU PHE n/a n/a
57 1XR9 - ILE LEU GLY PRO PRO GLY SER VAL TYR n/a n/a
58 1W0V - ARG ARG LEU PRO ILE PHE SER ARG LEU n/a n/a
59 1E27 - LEU PRO PRO VAL VAL ALA LYS GLU ILE n/a n/a
60 1JGE - GLY ARG PHE ALA ALA ALA ILE ALA LYS n/a n/a
61 3X14 - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
62 1N2R - GLU GLU PHE GLY ARG ALA PHE SER PHE n/a n/a
63 1AGD - GLY GLY LYS LYS LYS TYR LYS LEU n/a n/a
64 3LKO - LEU PRO PHE ASP ARG THR THR ILE MET n/a n/a
65 1SYS - GLU GLU PRO THR VAL ILE LYS LYS TYR n/a n/a
66 3KPM - GLU GLU TYR LEU LYS ALA TRP THR PHE n/a n/a
67 2AXF - ALA PRO GLN PRO ALA PRO GLU ASN ALA TYR n/a n/a
68 4NT6 - GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
69 3BWA - PHE PRO THR LYS ASP VAL ALA LEU n/a n/a
70 4O2F - HIS VAL ALA VAL GLU ASN ALA LEU n/a n/a
71 2H6P - LYS PRO ILE VAL VAL LEU HIS GLY TYR n/a n/a
72 3SKM - PHE LEU ARG GLY ARG ALA TYR VAL LEU n/a n/a
73 3UPR - HIS SER ILE THR TYR LEU LEU PRO VAL n/a n/a
74 1SYV - GLU GLU PHE GLY ARG ALA PHE SER PHE n/a n/a
75 3KPQ - GLU GLU TYR LEU LYS ALA TRP THR PHE n/a n/a
76 3LKS - LEU PRO PHE GLU LYS SER THR VAL MET n/a n/a
70% Homology Family (271)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 65 families.
1 4L8B - ALA SER ASN GLU HIS MET GLU THR MET n/a n/a
2 1HOC - ALA SER ASN GLU ASN MET GLU THR MET n/a n/a
3 4HUX - ALA SER ASN GLU ASN MET GLU THR MET n/a n/a
4 3CH1 - GLU GLY PRO ARG ASN GLN ASP TRP LEU n/a n/a
5 4HV8 - ALA SER ASN GLU ASN ILE GLU THR MET n/a n/a
6 1WBX - SER GLN LEU LYS ASN ASN ALA LYS GLU ILE n/a n/a
7 4HUV - ALA SER ASN GLU ASN TRP GLU THR MET n/a n/a
8 1INQ ic50 = 539 nM SER SER VAL VAL GLY VAL TRP TYR LEU n/a n/a
9 2ZOK - ABA SER LEU TRP ASN GLY PRO HIS LEU n/a n/a
10 1YN7 - SER SER LEU GLU ASN PHE ALA ALA TYR VAL n/a n/a
11 4HUU - ALA SER ASN GLU ASN ILE GLU THR MET n/a n/a
12 4QRT - GLU LEU ASN ARG LYS MET ILE TYR MET n/a n/a
13 2X4O - LYS LEU THR PRO LEU CYS VAL THR LEU n/a n/a
14 2C7U Kd = 100 nM SER LEU PHE ASN THR ILE ALA VAL LEU n/a n/a
15 1EEY - ILE LEU SER ALA LEU VAL GLY ILE VAL n/a n/a
16 1HHJ - ILE LEU LYS GLU PRO VAL HIS GLY VAL n/a n/a
17 2GTW - LEU ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
18 3GSV Kd = 57.5 uM ASN LEU VAL PRO GLN VAL ALA THR VAL n/a n/a
19 1QR1 - ILE ILE SER ALA VAL VAL GLY ILE LEU n/a n/a
20 3O3B - GLU LEU ALA GIC 3AZ LEU THR VAL n/a n/a
21 3D25 ic50 = 22 nM VAL LEU HIS ASP ASP LEU LEU GLU ALA n/a n/a
22 3BH9 ic50 = 116.9 nM ARG THR TYR SEP GLY PRO MET ASN LYS VAL n/a n/a
23 3OXS - PHE LEU PRO SER ASP PHE PHE PRO SER VAL n/a n/a
24 2V2X Kd = 5.2 uM SER LEU PHE ASN THR VAL ALA THR LEU n/a n/a
25 4JFO Kd = 140 uM ALA LEU ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
26 4GKS - PHE LEU THR GLY ILE GLY ILE ILE THR VAL n/a n/a
27 1T20 - SER LEU TYR ASN THR ILE ALA THR LEU n/a n/a
28 3GIV - SER LEU PHE ASN THR VAL ALA THR LEU TYR n/a n/a
29 1I1Y - TYR LEU LYS GLU PRO VAL HIS GLY VAL n/a n/a
30 3VXP - ARG TYR PRO LEU THR LEU GLY TRP CYS PHE n/a n/a
31 3PWL Kd = 140 uM LEU GLY TYR GLY PHE VAL ASN TYR ILE n/a n/a
32 3FT3 ic50 = 44 nM VAL LEU HIS ASP ASP LEU LEU GLU ALA n/a n/a
33 3UTQ - ALA LEU TRP GLY PRO ASP PRO ALA ALA ALA n/a n/a
34 4F7P - PHE TYR ARG TYR GLY PHE VAL ALA ASN PHE n/a n/a
35 3RL1 - ALA ILE PHE GLN SER SER MET THR LYS n/a n/a
36 2VLL - GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
37 1T1Z - ALA LEU TYR ASN THR ALA ALA ALA LEU n/a n/a
38 3FQT - GLY LEU LEU GLY SER PRO VAL ARG ALA n/a n/a
39 3GSQ - ASN LEU VAL PRO SER VAL ALA THR VAL n/a n/a
40 4NQX - CYS THR GLU LEU LYS LEU ASN ASP TYR n/a n/a
41 3VXN - ARG TYR PRO LEU THR PHE GLY TRP CYS PHE n/a n/a
42 3QFD Kd = 68 uM ALA ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
43 3O3A - BAL LEU ALA GIC 3AZ LEU THR VAL n/a n/a
44 2X4N - LYS ILE LEU GLY PRV VAL PHE PRQ VAL n/a n/a
45 4F7T - ARG TYR GLY PHE VAL ALA ASN PHE n/a n/a
46 1DUZ - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
47 3H7B Kd = 41 uM MET LEU TRP GLY TYR LEU GLN TYR VAL n/a n/a
48 3WL9 - ASN TYR THR PRO GLY PRO GLY ILE ARG PHE n/a n/a
49 4JFP - GLU LEU ALA ALA ILE GLY ILE LEU THR VAL n/a n/a
50 3FQW - ARG VAL ALA SER PRO THR SER GLY VAL n/a n/a
51 1TVB - ILE THR ASP GLN VAL PRO PHE SER VAL n/a n/a
52 1T1W - SER LEU PHE ASN THR ILE ALA VAL LEU n/a n/a
53 3GSU Kd = 58.2 uM ASN LEU VAL PRO THR VAL ALA THR VAL n/a n/a
54 3MYJ - TYR MET PHE PRO ASN ALA PRO TYR LEU n/a n/a
55 1Q94 - ALA ILE PHE GLN SER SER MET THR LYS n/a n/a
56 3H9H Kd = 5.4 uM MET LEU TRP GLY TYR LEU GLN TYR VAL n/a n/a
57 3O3E - BAL LEU ALA TIG 3AZ LEU THR VAL n/a n/a
58 3IXA Kd = 9.8 uM LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
59 4I4W - ILE LEU ALA LYS PHE LEU HIS ARG LEU n/a n/a
60 3FT2 ic50 = 44 nM VAL LEU CIR ASP ASP LEU LEU GLU ALA n/a n/a
61 2GT9 - GLU ALA ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
62 2X4R - ASN LEU VAL PRO MET VAL ALA THR VAL n/a n/a
63 2CLR - MET LEU LEU SER VAL PRO LEU LEU LEU GLY n/a n/a
64 4HWZ - ALA ILE PHE GLN SER SER MET THR LYS n/a n/a
65 1T22 - SER LEU TYR ASN THR VAL ALA THR LEU n/a n/a
66 1I4F - GLY VAL TYR ASP GLY ARG GLU HIS THR VAL n/a n/a
67 3PWJ Kd = 70 uM LEU LEU TYR GLY PHE VAL ASN TYR VAL n/a n/a
68 3NFN - ARG TYR PRO LEU THR PHE GLY TRP CYS PHE n/a n/a
69 3FQU - GLY LEU LEU GLY SEP PRO VAL ARG ALA n/a n/a
70 1JF1 - GLU LEU ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
71 1HHK - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
72 3FQN - TYR LEU ASP SER GLY ILE HIS SER GLY ALA n/a n/a
73 3BH8 ic50 = 11.2 nM ARG GLN ALA SEP ILE GLU LEU PRO SER MET n/a n/a
74 3BGM ic50 = 32.5 nM ARG GLN ALA SEP LEU SER ILE SER VAL n/a n/a
75 3O3D - GLU LEU ALA TIG 3AZ LEU THR VAL n/a n/a
76 3PWN Kd = 48 uM LEU LEU TYR GLY PHE VAL ASN TYR ILE n/a n/a
77 3BHB ic50 = 3.4 nM LYS MET ASP SEP PHE LEU ASP MET GLN LEU n/a n/a
78 1S9W - SER LEU LEU MET TRP ILE THR GLN CYS n/a n/a
79 4HX1 - SER VAL TYR ASP PHE PHE VAL TRP LEU n/a n/a
80 3MGT - LYS LEU TYR GLN ASN PRO THR THR TYR ILE n/a n/a
81 3MGO - ARG LEU TYR GLN ASN PRO THR THR TYR ILE n/a n/a
82 3FQX - ARG VAL ALA SEP PRO THR SER GLY VAL n/a n/a
83 1S9Y - SER LEU LEU MET TRP ILE THR GLN SER n/a n/a
84 1I7R - PHE ALA PRO GLY PHE PHE PRO TYR LEU n/a n/a
85 2AV7 - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
86 1X7Q - LYS THR PHE PRO PRO THR GLU PRO LYS n/a n/a
87 1S8D - SER LEU ALA ASN THR VAL ALA THR LEU n/a n/a
88 4F7M - LEU TYR ALA SER PRO GLN LEU GLU GLY PHE n/a n/a
89 3WLB - ASN TYR THR PRO GLY PRO GLY THR ARG PHE n/a n/a
90 3OX8 - PHE LEU PRO SER ASP PHE PHE PRO SER VAL n/a n/a
91 3GSX - ASN LEU VAL PRO MET VAL ALA VAL VAL n/a n/a
92 3RL2 - GLN VAL PRO LEU ARG PRO MET THR TYR LYS n/a n/a
93 2GUO - ALA ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
94 1T1X - SER LEU TYR LEU THR VAL ALA THR LEU n/a n/a
95 4JFQ - GLU LEU ALA GLY ILE GLY ILE ALA THR VAL n/a n/a
96 1DUY - LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
97 1I7U - ALA LEU TRP GLY PHE VAL PRO VAL LEU n/a n/a
98 1S9X - SER LEU LEU MET TRP ILE THR GLN ALA n/a n/a
99 3GSO Kd = 27.7 uM ASN LEU VAL PRO MET VAL ALA THR VAL n/a n/a
100 2X4P - MSE ILE LEU GLY PRV VAL PHE PRQ VAL n/a n/a
101 3FT4 ic50 = 1171 nM VAL LEU ARG ASP ASP LEU LEU GLU ALA n/a n/a
102 3HPJ - ARG MET PHE PRO ASN ALA PRO TYR LEU n/a n/a
103 3KLA Kd = 31.1 uM SER LEU LEU MET TRP ILE THR GLN LEU n/a n/a
104 1HHI - GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
105 1JHT - ALA LEU GLY ILE GLY ILE LEU THR VAL n/a n/a
106 4K7F - VAL CYS TRP GLY GLU LEU MET ASN LEU n/a n/a
107 2V2W Kd = 2.2 uM SER LEU TYR ASN THR VAL ALA THR LEU n/a n/a
108 2X4U - ILE LEU LYS GLU PRO VAL HIS GLY VAL n/a n/a
109 3I6L - GLN PHE LYS ASP ASN VAL ILE LEU LEU n/a n/a
110 1QVO - GLN VAL PRO LEU ARG PRO MET THR TYR LYS n/a n/a
111 2GIT - LEU LEU PHE GLY LYS PRO VAL TYR VAL n/a n/a
112 4NQV - CYS THR GLU LEU LYS LEU SER ASP TYR n/a n/a
113 2X70 - LYS ILE LEU GLY PRV VAL PHE PRQ VAL n/a n/a
114 1T21 - SER LEU TYR ASN THR VAL ALA THR LEU n/a n/a
115 3BO8 - GLU ALA ASP PRO THR GLY HIS SER TYR n/a n/a
116 2GTZ - ALA LEU GLY ILE GLY ILE LEU THR VAL n/a n/a
117 3OXR - PHE LEU PRO SER ASP PHE PHE PRO SER VAL n/a n/a
118 2AV1 - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
119 3GSR Kd = 60.2 uM ASN LEU VAL PRO VAL VAL ALA THR VAL n/a n/a
120 1T1Y - SER LEU TYR ASN VAL VAL ALA THR LEU n/a n/a
121 1EEZ - ILE LEU SER ALA LEU VAL GLY ILE LEU n/a n/a
122 1TVH - ILE MET ASP GLN VAL PRO PHE SER VAL n/a n/a
123 1QEW - PHE LEU TRP GLY PRO ARG ALA LEU VAL n/a n/a
124 1HSB - ALA VAL ALA n/a n/a
125 3REW Kd = 28.8 uM CYS LEU GLY GLY LEU LEU THR MET VAL n/a n/a
126 2HN7 ic50 = 31 nM ALA ILE MET PRO ALA ARG PHE TYR PRO LYS n/a n/a
127 3FQR - TYR LEU ASP SEP GLY ILE HIS SER GLY ALA n/a n/a
128 3I6G - GLY LEU MET TRP LEU SER TYR PHE VAL n/a n/a
129 4QRS - GLU LEU LYS ARG LYS MET ILE TYR MET n/a n/a
130 3X13 - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
131 3VRI - ARG VAL ALA GLN LEU GLU GLN VAL TYR ILE n/a n/a
132 3LKP - LEU PRO PHE ASP LYS SER THR ILE MET n/a n/a
133 3LV3 - SER ARG ARG TRP ARG ARG TRP ASN ARG n/a n/a
134 1A9E - LEU PRO PRO LEU ASP ILE THR PRO TYR n/a n/a
135 1UXW - ARG ARG ARG TRP ARG ARG LEU THR VAL n/a n/a
136 1W0W - ARG ARG LEU PRO ILE PHE SER ARG LEU n/a n/a
137 1XR8 - LEU GLU LYS ALA ARG GLY SER THR TYR n/a n/a
138 4G8I - LYS ARG TRP ILE ILE MET GLY LEU ASN LYS n/a n/a
139 1AGC - GLY GLY LYS LYS LYS TYR GLN LEU n/a n/a
140 1A1M - THR PRO TYR ASP ILE ASN GLN MET LEU n/a n/a
141 3SKO - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
142 3BXN - ILE ARG ALA ALA PRO PRO PRO LEU PHE n/a n/a
143 1A1O - LYS PRO ILE VAL GLN TYR ASP ASN PHE n/a n/a
144 2BVP - ILE SER PRO ARG THR LEU ASP ALA TRP n/a n/a
145 3DX7 - GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE n/a n/a
146 1M05 - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
147 1UXS - ARG ARG ARG TRP ARG ARG LEU THR VAL n/a n/a
148 2BSR - ARG ARG ILE TYR ASP LEU ILE GLU LEU n/a n/a
149 3VRJ - LEU THR THR LYS LEU THR ASN THR ASN ILE n/a n/a
150 2BST - SER ARG TYR TRP ALA ILE ARG THR ARG n/a n/a
151 3BP4 - ILE ARG ALA ALA PRO PRO PRO LEU PHE n/a n/a
152 3X12 - LEU SER SER PRO VAL THR LYS SER PHE n/a n/a
153 4O2C ic50 = 10 nM ACE SER HIS VAL ALA VAL GLU ASN ALA LEU n/a n/a
154 1AGB - GLY GLY ARG LYS LYS TYR LYS LEU n/a n/a
155 3LKQ - LEU PRO PHE ASP LYS THR THR ILE MET n/a n/a
156 2AXG - ALA PRO GLN PRO ALA PRO GLU ASN ALA TYR n/a n/a
157 1A1N - VAL PRO LEU ARG PRO MET THR TYR n/a n/a
158 1OGT - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
159 3KPO - GLU GLU TYR LEU LYS ALA TRP THR PHE n/a n/a
160 3DX6 - GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE n/a n/a
161 2A83 - ARG ARG ARG TRP HIS ARG TRP ARG LEU n/a n/a
162 3B6S - ARG ARG LYS TRP CIR ARG TRP HIS LEU n/a n/a
163 1JGD - ARG ARG LEU LEU ARG GLY HIS ASN GLN TYR n/a n/a
164 1AGF - GLY GLY LYS LYS ARG TYR LYS LEU n/a n/a
165 2CIK - LYS PRO ILE VAL VAL LEU HIS GLY TYR n/a n/a
166 3LKN - LEU PRO PHE GLU ARG ALA THR ILE MET n/a n/a
167 1HSA - ALA ARG ALA ALA ALA ALA ALA ALA ALA n/a n/a
168 1AGE - GLY GLY LYS LYS LYS TYR ARG LEU n/a n/a
169 2BSS - LYS ARG TRP ILE ILE LEU GLY LEU ASN LYS n/a n/a
170 4JQV - SER GLU LEU GLU ILE LYS ARG TYR n/a n/a
171 3C9N - VAL GLN GLN GLU SER SER PHE VAL MET n/a n/a
172 3X11 - LEU SER SER PRO VAL THR LYS SER PHE n/a n/a
173 1M6O - GLU GLU PHE GLY ARG ALA PHE SER PHE n/a n/a
174 3B3I - ARG ARG LYS TRP CIR ARG TRP HIS LEU n/a n/a
175 3DX8 - GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE n/a n/a
176 3KPL - GLU GLU TYR LEU GLN ALA PHE THR TYR n/a n/a
177 4G9D - LYS ARG TRP ILE ILE LEU GLY LEU ASN LYS n/a n/a
178 3LKR - LEU PRO PHE GLU ARG ALA THR VAL MET n/a n/a
179 3KPP - GLU GLU TYR LEU GLN ALA PHE THR TYR n/a n/a
180 1K5N - GLY ARG PHE ALA ALA ALA ILE ALA LYS n/a n/a
181 1OF2 - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
182 4O2E - SER HIS VAL ALA VAL GLU ASN ALA LEU n/a n/a
183 3BP7 - ILE ARG ALA ALA PRO PRO PRO LEU PHE n/a n/a
184 1XR9 - ILE LEU GLY PRO PRO GLY SER VAL TYR n/a n/a
185 1W0V - ARG ARG LEU PRO ILE PHE SER ARG LEU n/a n/a
186 1E27 - LEU PRO PRO VAL VAL ALA LYS GLU ILE n/a n/a
187 1JGE - GLY ARG PHE ALA ALA ALA ILE ALA LYS n/a n/a
188 3X14 - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
189 1N2R - GLU GLU PHE GLY ARG ALA PHE SER PHE n/a n/a
190 1AGD - GLY GLY LYS LYS LYS TYR LYS LEU n/a n/a
191 3LKO - LEU PRO PHE ASP ARG THR THR ILE MET n/a n/a
192 1SYS - GLU GLU PRO THR VAL ILE LYS LYS TYR n/a n/a
193 3KPM - GLU GLU TYR LEU LYS ALA TRP THR PHE n/a n/a
194 2AXF - ALA PRO GLN PRO ALA PRO GLU ASN ALA TYR n/a n/a
195 4NT6 - GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
196 3BWA - PHE PRO THR LYS ASP VAL ALA LEU n/a n/a
197 4O2F - HIS VAL ALA VAL GLU ASN ALA LEU n/a n/a
198 2H6P - LYS PRO ILE VAL VAL LEU HIS GLY TYR n/a n/a
199 3SKM - PHE LEU ARG GLY ARG ALA TYR VAL LEU n/a n/a
200 3UPR - HIS SER ILE THR TYR LEU LEU PRO VAL n/a n/a
201 1SYV - GLU GLU PHE GLY ARG ALA PHE SER PHE n/a n/a
202 3KPQ - GLU GLU TYR LEU LYS ALA TRP THR PHE n/a n/a
203 3LKS - LEU PRO PHE GLU LYS SER THR VAL MET n/a n/a
204 1WBZ - SER SER TYR ARG ARG PRO VAL GLY ILE n/a n/a
205 1NAN - ILE ASN PHE ASP PHE ASN THR ILE n/a n/a
206 1VAD - SER ARG ASP HIS SER ARG THR PRO MET n/a n/a
207 2VAA - ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
208 1FZM Kd = 20 nM ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
209 2VAB - PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
210 2CLV - SER GLN TYR TYR TYR ASN SER LEU n/a n/a
211 1KJ3 - LYS VAL ILE THR PHE ILE ASP LEU n/a n/a
212 4PV8 - ARG ABA PHE ILE PHE ALA ASN ILE n/a n/a
213 2ZSV - ARG ABA GLN ILE PHE ALA ASN ILE n/a n/a
214 1RJY - SER SER ILE GLU PHE ALA ARG LEU n/a n/a
215 1FZJ Kd = 8 nM ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
216 1G7P Kd = 90 nM SER ARG ASP HIS SER ARG THR PRO MET n/a n/a
217 2CLZ - ILE ASN PHE ASP PHE ASN THR ILE n/a n/a
218 1KPU - ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
219 1T0N - SER SER ILE GLU PHE ALA ARG LEU n/a n/a
220 1RK1 - SER GLU ILE GLU PHE ALA ARG LEU n/a n/a
221 3PAB Kd = 20 uM GLU ILE ILE ASN PHE GLU LYS LEU n/a n/a
222 1G7Q Kd = 877 nM SER ALA PRO ASP THR ARG PRO ALA n/a n/a
223 1FZO Kd = 13 nM PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
224 3P9L Kd = 6 uM SER ILE ILE ASN PHE GLU LYS LEU n/a n/a
225 1T0M - SER SER ILE GLU PHE ALA ARG LEU n/a n/a
226 4HS3 - ALA VAL TYR ASN PHE ALA THR MET n/a n/a
227 1FZK Kd = 4 nM PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
228 4PV9 - ARG ABA VAL ILE PHE ALA ASN ILE n/a n/a
229 1KPV - PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
230 1OSZ - ARG GLY TYR LEU TYR GLN GLY LEU n/a n/a
231 1LEK Kd = 1.3 nM GLU GLN TYR LYS PHE TYR SER VAL n/a n/a
232 1LK2 ic50 = 12 uM GLY ASN TYR SER PHE TYR ALA LEU n/a n/a
233 1LEG Kd = 11.1 nM GLU GLN TYR LYS PHE TYR SER VAL n/a n/a
234 1KBG - ARG GLY TYR VAL TYR ESC GLY LEU GAL GLA n/a n/a
235 3P9M Kd = 10 uM SER ILE ILE GLY PHE GLU LYS LEU n/a n/a
236 1VAC - SER ILE ILE ASN PHE GLU LYS LEU n/a n/a
237 1ZT1 - PHE GLU ALA ASN GLY ASN LEU ILE n/a n/a
238 1K8D - ILE LEU MET GLU HIS ILE HIS LYS LEU n/a n/a
239 1KJM - ALA GLN PHE SER ALA SER ALA SER ARG n/a n/a
240 3PWU - ILE PRO ALA TYR GLY VAL LEU THR ILE n/a n/a
241 3CC5 - LYS VAL PRO ARG ASN GLN ASP TRP LEU n/a n/a
242 1YN6 - SER SER LEU GLU ASN PHE ARG ALA TYR VAL n/a n/a
243 1JUF ic50 = 1400 nM SER SER VAL ILE GLY VAL TRP TYR LEU n/a n/a
244 1JPG - PHE GLN PRO GLN ASN GLY GLN PHE ILE n/a n/a
245 3CPL - ALA SER ASN GLU ASN ALA GLU THR MET n/a n/a
246 1LD9 - TYR PRO ASN VAL ASN ILE HIS ASN PHE n/a n/a
247 1WBY - SER SER LEU GLU ASN PHE ARG ALA TYR VAL n/a n/a
248 1S7T - LYS ALA VAL PHE ASN PHE ALA THR MET n/a n/a
249 1S7Q - LYS ALA VAL TYR ASN PHE ALA THR MET n/a n/a
250 3E6H - ILE GLY PRO GLY ARG ALA PHE TYR THR ILE n/a n/a
251 3ECB - ARG GLY PRO GLY ARG ALA PHE VAL THR ILE n/a n/a
252 3E6F - ILE GLY PRO GLY ARG ALA PHE TYR ALA n/a n/a
253 3VJ6 Kd = 17 uM ALA MET ALA PRO ARG THR LEU LEU LEU n/a n/a
254 1KJV - ASN PRO ARG ALA MET GLN ALA LEU LEU n/a n/a
255 1YDP - ARG ILE ILE PRO ARG HIS LEU GLN LEU n/a n/a
256 3KYN - LYS GLY PRO PRO ALA ALA LEU THR LEU n/a n/a
257 3KYO - LYS LEU PRO ALA GLN PHE TYR ILE LEU n/a n/a
258 3RWG ic50 = 2.8 nM MET HIS PRO ALA GLN THR SER GLN TRP n/a n/a
259 3RWI ic50 = 116 nM GLY SER HIS LEU GLU VAL GLN GLY TYR TRP n/a n/a
260 3RWE ic50 = 43 nM PHE GLN TRP MET GLY TYR GLU LEU TRP n/a n/a
261 3RWC ic50 = 7.6 nM ILE ARG TYR PRO LYS THR PHE GLY TRP n/a n/a
262 1BII - ARG GLY PRO GLY ARG ALA PHE VAL THR ILE n/a n/a
263 3FOM - ILE GLN GLN SER ILE GLU ARG ILE n/a n/a
264 3FON - VAL ASN ASP ILE PHE GLU ALA ILE n/a n/a
265 1S7U - LYS ALA VAL TYR ASN PHE ALA THR MET n/a n/a
266 1S7V - LYS ALA VAL TYR ASN LEU ALA THR MET n/a n/a
267 3BZF - VAL MET ALA PRO ARG ALA LEU LEU LEU n/a n/a
268 3BZE - VAL MET ALA PRO ARG THR LEU PHE LEU n/a n/a
269 4QRQ Kd = 2.48 uM HIS SER LYS LYS LYS CYS ASP GLU LEU n/a n/a
270 3QQ4 - ALA THR ALA ALA ALA THR GLU ALA TYR n/a n/a
271 1MHC - FME TYR PHE ILE ASN ILE LEU THR LEU n/a n/a
50% Homology Family (275)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 44 families.
1 4L8B - ALA SER ASN GLU HIS MET GLU THR MET n/a n/a
2 1HOC - ALA SER ASN GLU ASN MET GLU THR MET n/a n/a
3 4HUX - ALA SER ASN GLU ASN MET GLU THR MET n/a n/a
4 3CH1 - GLU GLY PRO ARG ASN GLN ASP TRP LEU n/a n/a
5 4HV8 - ALA SER ASN GLU ASN ILE GLU THR MET n/a n/a
6 1WBX - SER GLN LEU LYS ASN ASN ALA LYS GLU ILE n/a n/a
7 4HUV - ALA SER ASN GLU ASN TRP GLU THR MET n/a n/a
8 1INQ ic50 = 539 nM SER SER VAL VAL GLY VAL TRP TYR LEU n/a n/a
9 2ZOK - ABA SER LEU TRP ASN GLY PRO HIS LEU n/a n/a
10 1YN7 - SER SER LEU GLU ASN PHE ALA ALA TYR VAL n/a n/a
11 4HUU - ALA SER ASN GLU ASN ILE GLU THR MET n/a n/a
12 4QRT - GLU LEU ASN ARG LYS MET ILE TYR MET n/a n/a
13 2X4O - LYS LEU THR PRO LEU CYS VAL THR LEU n/a n/a
14 2C7U Kd = 100 nM SER LEU PHE ASN THR ILE ALA VAL LEU n/a n/a
15 1EEY - ILE LEU SER ALA LEU VAL GLY ILE VAL n/a n/a
16 1HHJ - ILE LEU LYS GLU PRO VAL HIS GLY VAL n/a n/a
17 2GTW - LEU ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
18 3GSV Kd = 57.5 uM ASN LEU VAL PRO GLN VAL ALA THR VAL n/a n/a
19 1QR1 - ILE ILE SER ALA VAL VAL GLY ILE LEU n/a n/a
20 3O3B - GLU LEU ALA GIC 3AZ LEU THR VAL n/a n/a
21 3D25 ic50 = 22 nM VAL LEU HIS ASP ASP LEU LEU GLU ALA n/a n/a
22 3BH9 ic50 = 116.9 nM ARG THR TYR SEP GLY PRO MET ASN LYS VAL n/a n/a
23 3OXS - PHE LEU PRO SER ASP PHE PHE PRO SER VAL n/a n/a
24 2V2X Kd = 5.2 uM SER LEU PHE ASN THR VAL ALA THR LEU n/a n/a
25 4JFO Kd = 140 uM ALA LEU ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
26 4GKS - PHE LEU THR GLY ILE GLY ILE ILE THR VAL n/a n/a
27 1T20 - SER LEU TYR ASN THR ILE ALA THR LEU n/a n/a
28 3GIV - SER LEU PHE ASN THR VAL ALA THR LEU TYR n/a n/a
29 1I1Y - TYR LEU LYS GLU PRO VAL HIS GLY VAL n/a n/a
30 3VXP - ARG TYR PRO LEU THR LEU GLY TRP CYS PHE n/a n/a
31 3PWL Kd = 140 uM LEU GLY TYR GLY PHE VAL ASN TYR ILE n/a n/a
32 3FT3 ic50 = 44 nM VAL LEU HIS ASP ASP LEU LEU GLU ALA n/a n/a
33 3UTQ - ALA LEU TRP GLY PRO ASP PRO ALA ALA ALA n/a n/a
34 4F7P - PHE TYR ARG TYR GLY PHE VAL ALA ASN PHE n/a n/a
35 3RL1 - ALA ILE PHE GLN SER SER MET THR LYS n/a n/a
36 2VLL - GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
37 1T1Z - ALA LEU TYR ASN THR ALA ALA ALA LEU n/a n/a
38 3FQT - GLY LEU LEU GLY SER PRO VAL ARG ALA n/a n/a
39 3GSQ - ASN LEU VAL PRO SER VAL ALA THR VAL n/a n/a
40 4NQX - CYS THR GLU LEU LYS LEU ASN ASP TYR n/a n/a
41 3VXN - ARG TYR PRO LEU THR PHE GLY TRP CYS PHE n/a n/a
42 3QFD Kd = 68 uM ALA ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
43 3O3A - BAL LEU ALA GIC 3AZ LEU THR VAL n/a n/a
44 2X4N - LYS ILE LEU GLY PRV VAL PHE PRQ VAL n/a n/a
45 4F7T - ARG TYR GLY PHE VAL ALA ASN PHE n/a n/a
46 1DUZ - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
47 3H7B Kd = 41 uM MET LEU TRP GLY TYR LEU GLN TYR VAL n/a n/a
48 3WL9 - ASN TYR THR PRO GLY PRO GLY ILE ARG PHE n/a n/a
49 4JFP - GLU LEU ALA ALA ILE GLY ILE LEU THR VAL n/a n/a
50 3FQW - ARG VAL ALA SER PRO THR SER GLY VAL n/a n/a
51 1TVB - ILE THR ASP GLN VAL PRO PHE SER VAL n/a n/a
52 1T1W - SER LEU PHE ASN THR ILE ALA VAL LEU n/a n/a
53 3GSU Kd = 58.2 uM ASN LEU VAL PRO THR VAL ALA THR VAL n/a n/a
54 3MYJ - TYR MET PHE PRO ASN ALA PRO TYR LEU n/a n/a
55 1Q94 - ALA ILE PHE GLN SER SER MET THR LYS n/a n/a
56 3H9H Kd = 5.4 uM MET LEU TRP GLY TYR LEU GLN TYR VAL n/a n/a
57 3O3E - BAL LEU ALA TIG 3AZ LEU THR VAL n/a n/a
58 3IXA Kd = 9.8 uM LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
59 4I4W - ILE LEU ALA LYS PHE LEU HIS ARG LEU n/a n/a
60 3FT2 ic50 = 44 nM VAL LEU CIR ASP ASP LEU LEU GLU ALA n/a n/a
61 2GT9 - GLU ALA ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
62 2X4R - ASN LEU VAL PRO MET VAL ALA THR VAL n/a n/a
63 2CLR - MET LEU LEU SER VAL PRO LEU LEU LEU GLY n/a n/a
64 4HWZ - ALA ILE PHE GLN SER SER MET THR LYS n/a n/a
65 1T22 - SER LEU TYR ASN THR VAL ALA THR LEU n/a n/a
66 1I4F - GLY VAL TYR ASP GLY ARG GLU HIS THR VAL n/a n/a
67 3PWJ Kd = 70 uM LEU LEU TYR GLY PHE VAL ASN TYR VAL n/a n/a
68 3NFN - ARG TYR PRO LEU THR PHE GLY TRP CYS PHE n/a n/a
69 3FQU - GLY LEU LEU GLY SEP PRO VAL ARG ALA n/a n/a
70 1JF1 - GLU LEU ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
71 1HHK - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
72 3FQN - TYR LEU ASP SER GLY ILE HIS SER GLY ALA n/a n/a
73 3BH8 ic50 = 11.2 nM ARG GLN ALA SEP ILE GLU LEU PRO SER MET n/a n/a
74 3BGM ic50 = 32.5 nM ARG GLN ALA SEP LEU SER ILE SER VAL n/a n/a
75 3O3D - GLU LEU ALA TIG 3AZ LEU THR VAL n/a n/a
76 3PWN Kd = 48 uM LEU LEU TYR GLY PHE VAL ASN TYR ILE n/a n/a
77 3BHB ic50 = 3.4 nM LYS MET ASP SEP PHE LEU ASP MET GLN LEU n/a n/a
78 1S9W - SER LEU LEU MET TRP ILE THR GLN CYS n/a n/a
79 4HX1 - SER VAL TYR ASP PHE PHE VAL TRP LEU n/a n/a
80 3MGT - LYS LEU TYR GLN ASN PRO THR THR TYR ILE n/a n/a
81 3MGO - ARG LEU TYR GLN ASN PRO THR THR TYR ILE n/a n/a
82 3FQX - ARG VAL ALA SEP PRO THR SER GLY VAL n/a n/a
83 1S9Y - SER LEU LEU MET TRP ILE THR GLN SER n/a n/a
84 1I7R - PHE ALA PRO GLY PHE PHE PRO TYR LEU n/a n/a
85 2AV7 - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
86 1X7Q - LYS THR PHE PRO PRO THR GLU PRO LYS n/a n/a
87 1S8D - SER LEU ALA ASN THR VAL ALA THR LEU n/a n/a
88 4F7M - LEU TYR ALA SER PRO GLN LEU GLU GLY PHE n/a n/a
89 3WLB - ASN TYR THR PRO GLY PRO GLY THR ARG PHE n/a n/a
90 3OX8 - PHE LEU PRO SER ASP PHE PHE PRO SER VAL n/a n/a
91 3GSX - ASN LEU VAL PRO MET VAL ALA VAL VAL n/a n/a
92 3RL2 - GLN VAL PRO LEU ARG PRO MET THR TYR LYS n/a n/a
93 2GUO - ALA ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
94 1T1X - SER LEU TYR LEU THR VAL ALA THR LEU n/a n/a
95 4JFQ - GLU LEU ALA GLY ILE GLY ILE ALA THR VAL n/a n/a
96 1DUY - LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
97 1I7U - ALA LEU TRP GLY PHE VAL PRO VAL LEU n/a n/a
98 1S9X - SER LEU LEU MET TRP ILE THR GLN ALA n/a n/a
99 3GSO Kd = 27.7 uM ASN LEU VAL PRO MET VAL ALA THR VAL n/a n/a
100 2X4P - MSE ILE LEU GLY PRV VAL PHE PRQ VAL n/a n/a
101 3FT4 ic50 = 1171 nM VAL LEU ARG ASP ASP LEU LEU GLU ALA n/a n/a
102 3HPJ - ARG MET PHE PRO ASN ALA PRO TYR LEU n/a n/a
103 3KLA Kd = 31.1 uM SER LEU LEU MET TRP ILE THR GLN LEU n/a n/a
104 1HHI - GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
105 1JHT - ALA LEU GLY ILE GLY ILE LEU THR VAL n/a n/a
106 4K7F - VAL CYS TRP GLY GLU LEU MET ASN LEU n/a n/a
107 2V2W Kd = 2.2 uM SER LEU TYR ASN THR VAL ALA THR LEU n/a n/a
108 2X4U - ILE LEU LYS GLU PRO VAL HIS GLY VAL n/a n/a
109 3I6L - GLN PHE LYS ASP ASN VAL ILE LEU LEU n/a n/a
110 1QVO - GLN VAL PRO LEU ARG PRO MET THR TYR LYS n/a n/a
111 2GIT - LEU LEU PHE GLY LYS PRO VAL TYR VAL n/a n/a
112 4NQV - CYS THR GLU LEU LYS LEU SER ASP TYR n/a n/a
113 2X70 - LYS ILE LEU GLY PRV VAL PHE PRQ VAL n/a n/a
114 1T21 - SER LEU TYR ASN THR VAL ALA THR LEU n/a n/a
115 3BO8 - GLU ALA ASP PRO THR GLY HIS SER TYR n/a n/a
116 2GTZ - ALA LEU GLY ILE GLY ILE LEU THR VAL n/a n/a
117 3OXR - PHE LEU PRO SER ASP PHE PHE PRO SER VAL n/a n/a
118 2AV1 - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
119 3GSR Kd = 60.2 uM ASN LEU VAL PRO VAL VAL ALA THR VAL n/a n/a
120 1T1Y - SER LEU TYR ASN VAL VAL ALA THR LEU n/a n/a
121 1EEZ - ILE LEU SER ALA LEU VAL GLY ILE LEU n/a n/a
122 1TVH - ILE MET ASP GLN VAL PRO PHE SER VAL n/a n/a
123 1QEW - PHE LEU TRP GLY PRO ARG ALA LEU VAL n/a n/a
124 1HSB - ALA VAL ALA n/a n/a
125 3REW Kd = 28.8 uM CYS LEU GLY GLY LEU LEU THR MET VAL n/a n/a
126 2HN7 ic50 = 31 nM ALA ILE MET PRO ALA ARG PHE TYR PRO LYS n/a n/a
127 3FQR - TYR LEU ASP SEP GLY ILE HIS SER GLY ALA n/a n/a
128 3I6G - GLY LEU MET TRP LEU SER TYR PHE VAL n/a n/a
129 4QRS - GLU LEU LYS ARG LYS MET ILE TYR MET n/a n/a
130 3X13 - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
131 3VRI - ARG VAL ALA GLN LEU GLU GLN VAL TYR ILE n/a n/a
132 3LKP - LEU PRO PHE ASP LYS SER THR ILE MET n/a n/a
133 3LV3 - SER ARG ARG TRP ARG ARG TRP ASN ARG n/a n/a
134 1A9E - LEU PRO PRO LEU ASP ILE THR PRO TYR n/a n/a
135 1UXW - ARG ARG ARG TRP ARG ARG LEU THR VAL n/a n/a
136 1W0W - ARG ARG LEU PRO ILE PHE SER ARG LEU n/a n/a
137 1XR8 - LEU GLU LYS ALA ARG GLY SER THR TYR n/a n/a
138 4G8I - LYS ARG TRP ILE ILE MET GLY LEU ASN LYS n/a n/a
139 1AGC - GLY GLY LYS LYS LYS TYR GLN LEU n/a n/a
140 1A1M - THR PRO TYR ASP ILE ASN GLN MET LEU n/a n/a
141 3SKO - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
142 3BXN - ILE ARG ALA ALA PRO PRO PRO LEU PHE n/a n/a
143 1A1O - LYS PRO ILE VAL GLN TYR ASP ASN PHE n/a n/a
144 2BVP - ILE SER PRO ARG THR LEU ASP ALA TRP n/a n/a
145 3DX7 - GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE n/a n/a
146 1M05 - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
147 1UXS - ARG ARG ARG TRP ARG ARG LEU THR VAL n/a n/a
148 2BSR - ARG ARG ILE TYR ASP LEU ILE GLU LEU n/a n/a
149 3VRJ - LEU THR THR LYS LEU THR ASN THR ASN ILE n/a n/a
150 2BST - SER ARG TYR TRP ALA ILE ARG THR ARG n/a n/a
151 3BP4 - ILE ARG ALA ALA PRO PRO PRO LEU PHE n/a n/a
152 3X12 - LEU SER SER PRO VAL THR LYS SER PHE n/a n/a
153 4O2C ic50 = 10 nM ACE SER HIS VAL ALA VAL GLU ASN ALA LEU n/a n/a
154 1AGB - GLY GLY ARG LYS LYS TYR LYS LEU n/a n/a
155 3LKQ - LEU PRO PHE ASP LYS THR THR ILE MET n/a n/a
156 2AXG - ALA PRO GLN PRO ALA PRO GLU ASN ALA TYR n/a n/a
157 1A1N - VAL PRO LEU ARG PRO MET THR TYR n/a n/a
158 1OGT - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
159 3KPO - GLU GLU TYR LEU LYS ALA TRP THR PHE n/a n/a
160 3DX6 - GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE n/a n/a
161 2A83 - ARG ARG ARG TRP HIS ARG TRP ARG LEU n/a n/a
162 3B6S - ARG ARG LYS TRP CIR ARG TRP HIS LEU n/a n/a
163 1JGD - ARG ARG LEU LEU ARG GLY HIS ASN GLN TYR n/a n/a
164 1AGF - GLY GLY LYS LYS ARG TYR LYS LEU n/a n/a
165 2CIK - LYS PRO ILE VAL VAL LEU HIS GLY TYR n/a n/a
166 3LKN - LEU PRO PHE GLU ARG ALA THR ILE MET n/a n/a
167 1HSA - ALA ARG ALA ALA ALA ALA ALA ALA ALA n/a n/a
168 1AGE - GLY GLY LYS LYS LYS TYR ARG LEU n/a n/a
169 2BSS - LYS ARG TRP ILE ILE LEU GLY LEU ASN LYS n/a n/a
170 4JQV - SER GLU LEU GLU ILE LYS ARG TYR n/a n/a
171 3C9N - VAL GLN GLN GLU SER SER PHE VAL MET n/a n/a
172 3X11 - LEU SER SER PRO VAL THR LYS SER PHE n/a n/a
173 1M6O - GLU GLU PHE GLY ARG ALA PHE SER PHE n/a n/a
174 3B3I - ARG ARG LYS TRP CIR ARG TRP HIS LEU n/a n/a
175 3DX8 - GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE n/a n/a
176 3KPL - GLU GLU TYR LEU GLN ALA PHE THR TYR n/a n/a
177 4G9D - LYS ARG TRP ILE ILE LEU GLY LEU ASN LYS n/a n/a
178 3LKR - LEU PRO PHE GLU ARG ALA THR VAL MET n/a n/a
179 3KPP - GLU GLU TYR LEU GLN ALA PHE THR TYR n/a n/a
180 1K5N - GLY ARG PHE ALA ALA ALA ILE ALA LYS n/a n/a
181 1OF2 - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
182 4O2E - SER HIS VAL ALA VAL GLU ASN ALA LEU n/a n/a
183 3BP7 - ILE ARG ALA ALA PRO PRO PRO LEU PHE n/a n/a
184 1XR9 - ILE LEU GLY PRO PRO GLY SER VAL TYR n/a n/a
185 1W0V - ARG ARG LEU PRO ILE PHE SER ARG LEU n/a n/a
186 1E27 - LEU PRO PRO VAL VAL ALA LYS GLU ILE n/a n/a
187 1JGE - GLY ARG PHE ALA ALA ALA ILE ALA LYS n/a n/a
188 3X14 - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
189 1N2R - GLU GLU PHE GLY ARG ALA PHE SER PHE n/a n/a
190 1AGD - GLY GLY LYS LYS LYS TYR LYS LEU n/a n/a
191 3LKO - LEU PRO PHE ASP ARG THR THR ILE MET n/a n/a
192 1SYS - GLU GLU PRO THR VAL ILE LYS LYS TYR n/a n/a
193 3KPM - GLU GLU TYR LEU LYS ALA TRP THR PHE n/a n/a
194 2AXF - ALA PRO GLN PRO ALA PRO GLU ASN ALA TYR n/a n/a
195 4NT6 - GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
196 3BWA - PHE PRO THR LYS ASP VAL ALA LEU n/a n/a
197 4O2F - HIS VAL ALA VAL GLU ASN ALA LEU n/a n/a
198 2H6P - LYS PRO ILE VAL VAL LEU HIS GLY TYR n/a n/a
199 3SKM - PHE LEU ARG GLY ARG ALA TYR VAL LEU n/a n/a
200 3UPR - HIS SER ILE THR TYR LEU LEU PRO VAL n/a n/a
201 1SYV - GLU GLU PHE GLY ARG ALA PHE SER PHE n/a n/a
202 3KPQ - GLU GLU TYR LEU LYS ALA TRP THR PHE n/a n/a
203 3LKS - LEU PRO PHE GLU LYS SER THR VAL MET n/a n/a
204 1WBZ - SER SER TYR ARG ARG PRO VAL GLY ILE n/a n/a
205 1NAN - ILE ASN PHE ASP PHE ASN THR ILE n/a n/a
206 1VAD - SER ARG ASP HIS SER ARG THR PRO MET n/a n/a
207 2VAA - ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
208 1FZM Kd = 20 nM ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
209 2VAB - PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
210 2CLV - SER GLN TYR TYR TYR ASN SER LEU n/a n/a
211 1KJ3 - LYS VAL ILE THR PHE ILE ASP LEU n/a n/a
212 4PV8 - ARG ABA PHE ILE PHE ALA ASN ILE n/a n/a
213 2ZSV - ARG ABA GLN ILE PHE ALA ASN ILE n/a n/a
214 1RJY - SER SER ILE GLU PHE ALA ARG LEU n/a n/a
215 1FZJ Kd = 8 nM ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
216 1G7P Kd = 90 nM SER ARG ASP HIS SER ARG THR PRO MET n/a n/a
217 2CLZ - ILE ASN PHE ASP PHE ASN THR ILE n/a n/a
218 1KPU - ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
219 1T0N - SER SER ILE GLU PHE ALA ARG LEU n/a n/a
220 1RK1 - SER GLU ILE GLU PHE ALA ARG LEU n/a n/a
221 3PAB Kd = 20 uM GLU ILE ILE ASN PHE GLU LYS LEU n/a n/a
222 1G7Q Kd = 877 nM SER ALA PRO ASP THR ARG PRO ALA n/a n/a
223 1FZO Kd = 13 nM PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
224 3P9L Kd = 6 uM SER ILE ILE ASN PHE GLU LYS LEU n/a n/a
225 1T0M - SER SER ILE GLU PHE ALA ARG LEU n/a n/a
226 4HS3 - ALA VAL TYR ASN PHE ALA THR MET n/a n/a
227 1FZK Kd = 4 nM PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
228 4PV9 - ARG ABA VAL ILE PHE ALA ASN ILE n/a n/a
229 1KPV - PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
230 1OSZ - ARG GLY TYR LEU TYR GLN GLY LEU n/a n/a
231 1LEK Kd = 1.3 nM GLU GLN TYR LYS PHE TYR SER VAL n/a n/a
232 1LK2 ic50 = 12 uM GLY ASN TYR SER PHE TYR ALA LEU n/a n/a
233 1LEG Kd = 11.1 nM GLU GLN TYR LYS PHE TYR SER VAL n/a n/a
234 1KBG - ARG GLY TYR VAL TYR ESC GLY LEU GAL GLA n/a n/a
235 3P9M Kd = 10 uM SER ILE ILE GLY PHE GLU LYS LEU n/a n/a
236 1VAC - SER ILE ILE ASN PHE GLU LYS LEU n/a n/a
237 1ZT1 - PHE GLU ALA ASN GLY ASN LEU ILE n/a n/a
238 1K8D - ILE LEU MET GLU HIS ILE HIS LYS LEU n/a n/a
239 1KJM - ALA GLN PHE SER ALA SER ALA SER ARG n/a n/a
240 3PWU - ILE PRO ALA TYR GLY VAL LEU THR ILE n/a n/a
241 3CC5 - LYS VAL PRO ARG ASN GLN ASP TRP LEU n/a n/a
242 1YN6 - SER SER LEU GLU ASN PHE ARG ALA TYR VAL n/a n/a
243 1JUF ic50 = 1400 nM SER SER VAL ILE GLY VAL TRP TYR LEU n/a n/a
244 1JPG - PHE GLN PRO GLN ASN GLY GLN PHE ILE n/a n/a
245 3CPL - ALA SER ASN GLU ASN ALA GLU THR MET n/a n/a
246 1LD9 - TYR PRO ASN VAL ASN ILE HIS ASN PHE n/a n/a
247 1WBY - SER SER LEU GLU ASN PHE ARG ALA TYR VAL n/a n/a
248 1S7T - LYS ALA VAL PHE ASN PHE ALA THR MET n/a n/a
249 1S7Q - LYS ALA VAL TYR ASN PHE ALA THR MET n/a n/a
250 4G43 - ILE ASP TRP PHE GLU GLY LYS GLU n/a n/a
251 4E0R - ILE ASP TRP PHE ASP GLY LYS GLU n/a n/a
252 4G42 - ILE ASP TRP PHE ASP GLY LYS ASP n/a n/a
253 3E6H - ILE GLY PRO GLY ARG ALA PHE TYR THR ILE n/a n/a
254 3ECB - ARG GLY PRO GLY ARG ALA PHE VAL THR ILE n/a n/a
255 3E6F - ILE GLY PRO GLY ARG ALA PHE TYR ALA n/a n/a
256 3VJ6 Kd = 17 uM ALA MET ALA PRO ARG THR LEU LEU LEU n/a n/a
257 1KJV - ASN PRO ARG ALA MET GLN ALA LEU LEU n/a n/a
258 1YDP - ARG ILE ILE PRO ARG HIS LEU GLN LEU n/a n/a
259 3KYN - LYS GLY PRO PRO ALA ALA LEU THR LEU n/a n/a
260 3KYO - LYS LEU PRO ALA GLN PHE TYR ILE LEU n/a n/a
261 3RWG ic50 = 2.8 nM MET HIS PRO ALA GLN THR SER GLN TRP n/a n/a
262 3RWI ic50 = 116 nM GLY SER HIS LEU GLU VAL GLN GLY TYR TRP n/a n/a
263 3RWE ic50 = 43 nM PHE GLN TRP MET GLY TYR GLU LEU TRP n/a n/a
264 3RWC ic50 = 7.6 nM ILE ARG TYR PRO LYS THR PHE GLY TRP n/a n/a
265 1BII - ARG GLY PRO GLY ARG ALA PHE VAL THR ILE n/a n/a
266 3FOM - ILE GLN GLN SER ILE GLU ARG ILE n/a n/a
267 3FON - VAL ASN ASP ILE PHE GLU ALA ILE n/a n/a
268 1S7U - LYS ALA VAL TYR ASN PHE ALA THR MET n/a n/a
269 1S7V - LYS ALA VAL TYR ASN LEU ALA THR MET n/a n/a
270 3BZF - VAL MET ALA PRO ARG ALA LEU LEU LEU n/a n/a
271 3BZE - VAL MET ALA PRO ARG THR LEU PHE LEU n/a n/a
272 4QRQ Kd = 2.48 uM HIS SER LYS LYS LYS CYS ASP GLU LEU n/a n/a
273 1TMC - GLU VAL ALA PRO PRO GLU TYR HIS ARG LYS n/a n/a
274 3QQ4 - ALA THR ALA ALA ALA THR GLU ALA TYR n/a n/a
275 1MHC - FME TYR PHE ILE ASN ILE LEU THR LEU n/a n/a
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: VAL PRO LEU ARG PRO MET THR TYR; Similar ligands found: 132
No: Ligand ECFP6 Tc MDL keys Tc
1 VAL PRO LEU ARG PRO MET THR TYR 1 1
2 GLN VAL PRO LEU ARG PRO MET THR TYR LYS 0.723684 0.986486
3 VAL MET ALA PRO ARG THR LEU PHE LEU 0.622517 0.932432
4 ALA MET ALA PRO ARG THR LEU LEU LEU 0.591549 0.905405
5 ARG MET PHE PRO ASN ALA PRO TYR LEU 0.555556 0.923077
6 LEU PRO PHE GLU ARG ALA THR VAL MET 0.539394 0.932432
7 ARG TYR PRO LEU THR PHE GLY TRP CYS PHE 0.530387 0.897436
8 ARG TYR PRO LEU THR LEU GLY TRP CYS PHE 0.530387 0.897436
9 LEU PRO PHE ASP ARG THR THR ILE MET 0.527607 0.933333
10 ALA ILE MET PRO ALA ARG PHE TYR PRO LYS 0.523256 0.907895
11 GLN MET PRO THR GLU ASP GLU TYR 0.522581 0.878378
12 VAL MET ALA PRO ARG ALA LEU LEU LEU 0.520548 0.837838
13 LEU PRO PHE GLU ARG ALA THR ILE MET 0.511765 0.92
14 ILE ARG TYR PRO LYS THR PHE GLY TRP 0.511236 0.848101
15 ARG LEU TYR GLN ASN PRO THR THR TYR ILE 0.508982 0.871795
16 GLN PRO PRO VAL PRO PRO GLN ARG PRO MET 0.503226 0.864865
17 GLY ARG PRO ARG THR THR SER PHE ALA GLU 0.503067 0.853333
18 TYR MET PHE PRO ASN ALA PRO TYR LEU 0.5 0.833333
19 ARG THR TYR SEP GLY PRO MET ASN LYS VAL 0.497238 0.890244
20 ARG PHE PRO LEU THR PHE GLY TRP CYS PHE 0.497238 0.871795
21 ALA ASN SER ARG TYR PRO THR SER ILE ILE 0.496933 0.87013
22 ILE ARG ALA ALA PRO PRO PRO LEU PHE 0.493671 0.826667
23 GLU GLU PRO THR VAL ILE LYS LYS TYR 0.490683 0.8
24 ASN ARG PRO VAL TYR ILE PRO ARG PRO PRO 0.490446 0.878378
25 LYS PRO VAL LEU ARG THR ALA 0.489933 0.863014
26 PRO LYS ARG PRO THR THR LEU ASN LEU PHE 0.488235 0.88
27 THR PRO TYR ASP ILE ASN GLN MET LEU 0.48503 0.855263
28 ARG VAL SER PRO SER THR SER TYR THR PRO 0.482759 0.797297
29 SER SER TYR ARG ARG PRO VAL GLY ILE 0.481707 0.894737
30 ASN PRO ARG ALA MET GLN ALA LEU LEU 0.480519 0.84
31 ILE PRO ALA TYR GLY VAL LEU THR ILE 0.478261 0.8
32 SER ALA PRO ASP THR ARG PRO ALA 0.476821 0.828947
33 DPN PRO DAR DTH NH2 0.475177 0.808219
34 ALA ASN SER ARG TRP PRO THR THR ARG LEU 0.474684 0.881579
35 PHE ASN ARG PRO VAL 0.472603 0.8
36 DTY ILE ARG LEU LPD 0.470199 0.851351
37 LEU GLN ARG VAL LEU SEP ALA PRO PHE 0.469136 0.765432
38 ASN TYR THR PRO GLY PRO GLY THR ARG PHE 0.468208 0.87013
39 LEU PRO PHE GLU LYS SER THR VAL MET 0.467066 0.84
40 LEU PRO PHE ASP LYS THR THR ILE MET 0.461078 0.826667
41 ILE SER PRO ARG THR LEU ASP ALA TRP 0.459016 0.848101
42 PRO ARG ARG PRO VAL ILE MET ARG ARG 0.455696 0.837838
43 ASN LEU VAL PRO MET VAL ALA THR VAL 0.455128 0.8
44 PRO PRO ARG PRO ILE TYR ASN ARG ASN 0.454545 0.868421
45 PHE TYR ARG ALA LEU MET 0.453947 0.746667
46 PTR VAL PRO MET LEU 0.453947 0.772152
47 GLY TYR GLN ASP TYR GLU PRO GLU ALA 0.452703 0.72973
48 ASN ARG PRO ILE LEU SER LEU 0.45098 0.805195
49 LYS LEU TYR GLN ASN PRO THR THR TYR ILE 0.447059 0.782051
50 ARG PRO ARG PRO ASP ASP LEU GLU ILE 0.446541 0.813333
51 LEU SER SER PRO VAL THR LYS SER PHE 0.446541 0.797297
52 GLU LEU LYS ARG LYS MET ILE TYR MET 0.446541 0.773333
53 ARG LEU TYR HIS SEP LEU PRO ALA 0.445087 0.807229
54 GLN ASN GLY PTR VAL ASN PRO THR TYR 0.444444 0.73494
55 ASP LEU THR ARG PRO 0.444444 0.851351
56 HIS SER ILE THR TYR LEU LEU PRO VAL 0.444444 0.807692
57 LEU LEU PHE GLY LYS PRO VAL TYR VAL 0.443787 0.74026
58 TYR SEP PRO THR SEP PRO SER 0.442953 0.75
59 GLU ARG THR ILE PRO ILE THR ARG GLU 0.441558 0.84
60 ASN TYR THR PRO GLY PRO GLY ILE ARG PHE 0.441341 0.858974
61 ASN PHE ASP ASN PRO VAL TYR ARG LYS THR 0.441341 0.883117
62 MET TYR TRP TYR PRO TYR 0.440252 0.766234
63 LEU LEU PHE GLY TYR PRO VAL TYR VAL 0.439759 0.75
64 LEU LEU PHE GLY PHE PRO VAL TYR VAL 0.439759 0.75
65 SER ARG ASP HIS SER ARG THR PRO MET 0.439306 0.896104
66 ARG PRO LYS PRO LEU VAL ASP PRO 0.438356 0.794521
67 ALA PRO GLN PRO ALA PRO GLU ASN ALA TYR 0.438272 0.776316
68 TYR LEU LYS GLU PRO VAL HIS GLY VAL 0.436782 0.766234
69 LYS PRO ILE VAL VAL LEU HIS GLY TYR 0.436782 0.75641
70 ILE GLY PRO GLY ARG ALA PHE TYR THR ILE 0.435754 0.857143
71 ASP TYR GLU PRO ILE PRO GLU GLU ALA PHE 0.435294 0.753247
72 DPN PRO DAR ILE NH2 0.434483 0.756757
73 LEU PRO PHE ASP LYS SER THR ILE MET 0.434286 0.828947
74 DHI PRO PHE HIS LEU LEU VAL TYR 0.431818 0.753247
75 LYS ALA PRO ARG ALY GLN LEU ALA THR LYS 0.431138 0.853333
76 LEU PRO PRO LEU ASP ILE THR PRO TYR 0.431138 0.8
77 ARG ARG LEU PRO ILE PHE SER ARG LEU 0.431138 0.866667
78 TYR PRO TYR 0.430769 0.68
79 GLY GLU ARG THR ILE PRO ILE THR ARG GLU 0.43038 0.84
80 SER HIS PRO ARG PRO ILE ARG VAL 0.430303 0.844156
81 ALA ARG THR MLY GLN THR ALA ARG TYR 0.429487 0.853333
82 PHE ALA PRO GLY PHE PHE PRO TYR LEU 0.429448 0.766234
83 LYS THR PHE PRO PRO THR GLU PRO LYS 0.427711 0.77027
84 CYS THR PRO SER ARG 0.424658 0.824324
85 ALA ASN SER ARG PHE PRO THR SER ILE ILE 0.424419 0.831169
86 ILE SER TYR GLY ASN ASP ALA LEU MET PRO 0.423729 0.857143
87 DPN PRO ARG 0.423358 0.739726
88 LEU PHE GLY TYR PRO VAL TYR VAL 0.423313 0.75
89 GLU LEU ASN ARG LYS MET ILE TYR MET 0.422619 0.789474
90 LYS LEU THR PRO LEU CYS VAL THR LEU 0.422078 0.794521
91 MET TRP ARG PRO TRP 0.420732 0.792208
92 ALA ARG SER HIS SEP TYR PRO ALA 0.420455 0.795181
93 LEU TYR ALA SER PRO GLN LEU GLU GLY PHE 0.418079 0.779221
94 SER GLU LEU GLU ILE LYS ARG TYR 0.417722 0.75
95 MET SER LEU PRO GLY ARG TRP LYS PRO LYS 0.417112 0.897436
96 ASN LEU VAL PRO MET VAL ALA VAL VAL 0.416667 0.733333
97 ASN LEU VAL PRO MET VAL ALA ALA VAL 0.416667 0.733333
98 LYS GLY PRO PRO LEU PRO ARG PRO ARG VAL 0.416107 0.794521
99 VAL VAL ARG PRO GLY SER LEU ASP LEU PRO 0.415205 0.853333
100 ASN GLY TYR GLU ASN PRO THR TYR LYS 0.415205 0.779221
101 GLN ASN TYR PRO ILE VAL GLN 0.415094 0.776316
102 TYR PRO SER LYS PRO ASP ASN PRO GLY GLU 0.414474 0.773333
103 ALA THR VAL ARG THR TYR SER CYS 0.414474 0.756757
104 GLU LEU LYS TPO GLU ARG TYR 0.4125 0.725
105 PHE PRO THR LYS ASP VAL ALA LEU 0.412121 0.783784
106 LEU GLU LYS ALA ARG GLY SER THR TYR 0.411765 0.786667
107 PHE ALA PRO GLY ASN TYR PRO ALA LEU 0.411765 0.794872
108 ARG ILE ILE PRO ARG HIS LEU GLN LEU 0.411429 0.792208
109 ALA PRO THR MET PRO PRO PRO LEU PRO PRO 0.410596 0.824324
110 ALA LEU PRO HIS ALA ILE LEU ARG LEU 0.409357 0.789474
111 ARG PRO GLY ASN PHE LEU GLN SER ARG PRO 0.40884 0.844156
112 GLY LEU LEU GLY SER PRO VAL ARG ALA 0.408805 0.8
113 VAL TYR PRO IAS HIS ALA 0.408537 0.74026
114 GLY PHE ARG PRO 0.408451 0.743243
115 LYS LEU PRO ALA GLN PHE TYR ILE LEU 0.408046 0.753247
116 ALA ASN SER ARG TRP PRO THR SER ALY ILE 0.407821 0.848101
117 ARG GLN ALA SEP ILE GLU LEU PRO SER MET 0.406417 0.817073
118 PHE ASN PHE PRO GLN ILE THR 0.40625 0.730769
119 VAL ORN LEU DPN PRO VAL ORN LEU DPN PRO 0.40625 0.693333
120 LYS GLN GLU PRO GLN GLU ILE ASP PHE 0.405882 0.706667
121 PRO THR SEP PRO SER TYR 0.404908 0.7375
122 DPN PRO DAR CYS NH2 0.40411 0.739726
123 GLU VAL ALA PRO PRO GLU TYR HIS ARG LYS 0.403141 0.833333
124 THR PRO ARG ARG SER MLZ SER ALA 0.402597 0.866667
125 ARG ARG ARG GLU ARG SER PRO THR ARG 0.402516 0.813333
126 SER TYR SEP PRO THR SEP PRO SEP TYR SER 0.402516 0.725
127 LEU PRO GLU THR GLY 0.401408 0.743243
128 SER PRO THR SER PRO SEP TYR SER PRO PRO 0.401198 0.7375
129 ILE LEU GLY PRO PRO GLY SER VAL TYR 0.401163 0.815789
130 ILE LEU LYS GLU PRO VAL HIS GLY VAL 0.4 0.701299
131 GLY TYR GLU ASN PRO THR TYR LYS PHE PHE 0.4 0.766234
132 ALA ASN SER ARG VAL PRO THR SER ILE ILE 0.4 0.84
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4O2C; Ligand: ACE SER HIS VAL ALA VAL GLU ASN ALA LEU; Similar sites found: 138
This union binding pocket(no: 1) in the query (biounit: 4o2c.bio1) has 83 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc)
1 3TDC 0EU 0.0001415 0.6262
2 2OI9 GLN LEU SER PRO PHE PRO PHE ASP LEU 0.00000004835 0.57479
3 1TV5 N8E 0.0003139 0.55748
4 2VWA PTY 0.0005814 0.54675
5 2G30 ALA ALA PHE 0.0001738 0.53262
6 1OFL NGK GCD 0.001447 0.51551
7 1NF8 BOG 0.002344 0.50878
8 2VWA PTY 0.002263 0.50767
9 1TV5 N8E 0.002102 0.50665
10 1FO0 ILE ASN PHE ASP PHE ASN THR ILE 0.00000000000622 0.49913
11 3MG9 GHP 3MY 3FG GHP GHP OMY 3FG 0.005207 0.49566
12 3KYF 5GP 5GP 0.002692 0.48995
13 4L8D ALA SER ASN GLU ASP MET GLU THR MET 0.0000000000005635 0.4891
14 2VWA PTY 0.00621 0.48448
15 2XG5 EC5 0.006017 0.48277
16 2XG5 EC2 0.006017 0.48277
17 2HZQ STR 0.006161 0.48197
18 3KYG 5GP 5GP 0.002333 0.47965
19 4IAW LIZ 0.005278 0.47854
20 3KO0 TFP 0.007625 0.4777
21 4FFG 0U8 0.007072 0.47481
22 3KO0 TFP 0.008855 0.47253
23 3KO0 TFP 0.009462 0.47229
24 2ZHL NAG GAL GAL NAG 0.005838 0.47141
25 2VWA PTY 0.009191 0.46491
26 1J78 OLA 0.02126 0.46303
27 4F4S EFO 0.01249 0.46194
28 3W54 RNB 0.006395 0.46082
29 3KYG 5GP 5GP 0.003959 0.4602
30 4F4S EFO 0.01556 0.4564
31 1GEG GLC 0.02475 0.45576
32 3TJH SER PRO LEU ASP SER LEU TRP TRP ILE 0.00000000392 0.45574
33 1O9U ADZ 0.01103 0.45415
34 4IAW LIZ 0.01279 0.45259
35 4BG4 ADP 0.007517 0.44972
36 4I67 G G G RPC 0.01499 0.44877
37 4IAW LIZ 0.01539 0.44814
38 3ZJX BOG 0.02329 0.44713
39 1IIU RTL 0.005481 0.44654
40 4BG4 ADP 0.009402 0.44145
41 4LWU 20U 0.0149 0.44135
42 3RGA LSB 0.01319 0.44063
43 3B6C SDN 0.02908 0.44059
44 3OQJ 3CX 0.02141 0.44018
45 4IVD 15T 0.008609 0.44016
46 2Z77 HE7 0.005775 0.43942
47 2Z77 HE7 0.005775 0.43942
48 2Z77 HE7 0.005775 0.43942
49 1D2S DHT 0.01408 0.43916
50 3B6R ADP 0.01411 0.4391
51 4FFG 0U8 0.03094 0.43901
52 4MGD 27N 0.01657 0.43889
53 4IVD 15T 0.00918 0.43879
54 2JF9 OHT 0.0061 0.43831
55 3R9V DXC 0.03306 0.43831
56 1RYD GLC 0.0341 0.43764
57 4NS0 PIO 0.03767 0.43641
58 1SDW IYT 0.02194 0.43589
59 4FE2 AIR 0.02597 0.43551
60 4KBA 1QM 0.02282 0.43496
61 3RV5 DXC 0.0007051 0.43417
62 3F8C HT1 0.04517 0.43303
63 4BQY FNT 0.02499 0.43281
64 3KO0 TFP 0.04291 0.43224
65 4H6B 10X 0.02585 0.432
66 1NRL SRL 0.01547 0.43062
67 2PEH LYS ARG LYS SER ARG TRP ASP GLU THR PRO 0.03179 0.4306
68 4H6B 10X 0.02756 0.43048
69 3RF4 FUN 0.04342 0.43038
70 3RF4 FUN 0.04342 0.43038
71 4O9S 2RY 0.01026 0.42779
72 1QY1 PRZ 0.01537 0.42779
73 1QY1 PRZ 0.01537 0.42779
74 3EZ2 ADP 0.04159 0.42765
75 1UNB AKG 0.006459 0.42657
76 4DK7 0KS 0.01865 0.42655
77 1KDK DHT 0.01308 0.42554
78 2WPW ACO 0.02574 0.42547
79 2WPW ACO 0.02701 0.42437
80 2WPW ACO 0.02766 0.42383
81 2WPW ACO 0.02788 0.42366
82 1ELW GLY PRO THR ILE GLU GLU VAL ASP 0.03674 0.42365
83 3QSB 743 0.04398 0.42269
84 4DR9 BB2 0.02985 0.4221
85 3ALN ANP 0.04611 0.42154
86 3W54 RNB 0.03578 0.42103
87 4OAS 2SW 0.03675 0.42041
88 1I7M CG 0.04876 0.42017
89 1I7M CG 0.04876 0.42017
90 3QKD HI0 0.0135 0.41968
91 2VGD XYP XYP XYP FX3 0.03982 0.41854
92 3RY9 1CA 0.03083 0.41838
93 1UNB PN1 0.007852 0.41822
94 4E2J MOF 0.02127 0.4181
95 1YRX FMN 0.03578 0.41796
96 3RY9 1CA 0.03222 0.41739
97 4O9S 2RY 0.01342 0.41733
98 4O9S 2RY 0.01342 0.41733
99 2CM4 RCL 0.02207 0.41732
100 3GN8 DEX 0.02542 0.41699
101 3UZP 0CK 0.03292 0.41692
102 2WA4 069 0.04922 0.41666
103 3E3U NVC 0.04333 0.41656
104 4KBA 1QM 0.03348 0.41654
105 4KBA 1QM 0.03348 0.41654
106 2TPI ILE VAL 0.03379 0.41633
107 3JRX S1A 0.03582 0.41502
108 3UZP 0CK 0.03159 0.41501
109 3UZP 0CK 0.03159 0.41501
110 2BYC FMN 0.04786 0.41423
111 3B1M KRC 0.003873 0.41385
112 2Z77 HE7 0.02948 0.41381
113 4MG8 27J 0.04911 0.41362
114 4NFN 2KC 0.04467 0.41287
115 1T76 DHT 0.03994 0.41258
116 4I9B NAD 0.03176 0.4122
117 4KBA 1QM 0.04726 0.41158
118 4P6W MOF 0.02768 0.41003
119 1ZDT PEF 0.02259 0.40938
120 3U3U EAH 0.04119 0.40917
121 4IEN GDP 0.04673 0.40904
122 1N9L FMN 0.04334 0.40805
123 1N9L FMN 0.04334 0.40805
124 1N9L FMN 0.04334 0.40805
125 3GN8 DEX 0.03992 0.40726
126 3OKI OKI 0.04093 0.40672
127 3L9R L9R 0.000001254 0.40617
128 4QC6 30N 0.0342 0.40563
129 1K7L 544 0.02919 0.40424
130 4E2J MOF 0.03667 0.40417
131 4QC6 30N 0.03676 0.40412
132 4MPN PV0 0.03007 0.40364
133 1FBY REA 0.03365 0.40363
134 1K7L 544 0.02765 0.4031
135 3P7N FMN 0.04923 0.40271
136 1GZW GAL BGC 0.04128 0.40171
137 1K7L 544 0.03114 0.40075
138 4HK8 XYP XYP XYP XYP XYP XYP 0.0444 0.40017
Feedback