Receptor
PDB id Resolution Class Description Source Keywords
1A1N 2 Å NON-ENZYME: IMMUNE MHC CLASS I MOLECULE B*3501 COMPLEXED WITH PEPTIDE VPLRPMTY FROM THE NEF PROTEIN (75-82) OF HIV1 HOMO SAPIENS MAJOR HISTOCOMPATIBILITY ANTIGEN MHC HLA HLA-B3501 HIV NEF COMPLEX (ANTIGEN/PEPTIDE)
Ref.: AN ALTERED POSITION OF THE ALPHA 2 HELIX OF MHC CLASS I IS REVEALED BY THE CRYSTAL STRUCTURE OF HLA-B*3501. IMMUNITY V. 4 203 1996
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
VAL PRO LEU ARG PRO MET THR TYR C:1;
Valid;
none;
submit data
977.219 n/a S(CCC...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4O2C 1.8 Å NON-ENZYME: IMMUNE AN NT-ACETYLATED PEPTIDE COMPLEXED WITH HLA-B*3901 HOMO SAPIENS IG-LIKE IMMUNE SYSTEM
Ref.: N ALPHA-TERMINAL ACETYLATION FOR T CELL RECOGNITION MOLECULAR BASIS OF MHC CLASS I-RESTRICTED N ALPHA-ACETYLPEPTIDE PRESENTATION J.IMMUNOL. V. 192 5509 2014
Members (76)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 180 families.
1 2RFX - LEU SER SER PRO VAL THR LYS SER PHE n/a n/a
2 3KPN - GLU GLU TYR LEU GLN ALA PHE THR TYR n/a n/a
3 3X13 - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
4 3VRI - ARG VAL ALA GLN LEU GLU GLN VAL TYR ILE n/a n/a
5 3LKP - LEU PRO PHE ASP LYS SER THR ILE MET n/a n/a
6 3LV3 - SER ARG ARG TRP ARG ARG TRP ASN ARG n/a n/a
7 1A9E - LEU PRO PRO LEU ASP ILE THR PRO TYR n/a n/a
8 1UXW - ARG ARG ARG TRP ARG ARG LEU THR VAL n/a n/a
9 1W0W - ARG ARG LEU PRO ILE PHE SER ARG LEU n/a n/a
10 1XR8 - LEU GLU LYS ALA ARG GLY SER THR TYR n/a n/a
11 4G8I - LYS ARG TRP ILE ILE MET GLY LEU ASN LYS n/a n/a
12 1AGC - GLY GLY LYS LYS LYS TYR GLN LEU n/a n/a
13 1A1M - THR PRO TYR ASP ILE ASN GLN MET LEU n/a n/a
14 3SKO - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
15 3BXN - ILE ARG ALA ALA PRO PRO PRO LEU PHE n/a n/a
16 1A1O - LYS PRO ILE VAL GLN TYR ASP ASN PHE n/a n/a
17 2BVP - ILE SER PRO ARG THR LEU ASP ALA TRP n/a n/a
18 3DX7 - GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE n/a n/a
19 1M05 - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
20 1UXS - ARG ARG ARG TRP ARG ARG LEU THR VAL n/a n/a
21 2BSR - ARG ARG ILE TYR ASP LEU ILE GLU LEU n/a n/a
22 3VRJ - LEU THR THR LYS LEU THR ASN THR ASN ILE n/a n/a
23 2BST - SER ARG TYR TRP ALA ILE ARG THR ARG n/a n/a
24 3BP4 - ILE ARG ALA ALA PRO PRO PRO LEU PHE n/a n/a
25 3X12 - LEU SER SER PRO VAL THR LYS SER PHE n/a n/a
26 4O2C ic50 = 10 nM ACE SER HIS VAL ALA VAL GLU ASN ALA LEU n/a n/a
27 1AGB - GLY GLY ARG LYS LYS TYR LYS LEU n/a n/a
28 3LKQ - LEU PRO PHE ASP LYS THR THR ILE MET n/a n/a
29 2AXG - ALA PRO GLN PRO ALA PRO GLU ASN ALA TYR n/a n/a
30 1A1N - VAL PRO LEU ARG PRO MET THR TYR n/a n/a
31 1OGT - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
32 3KPO - GLU GLU TYR LEU LYS ALA TRP THR PHE n/a n/a
33 3DX6 - GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE n/a n/a
34 2A83 - ARG ARG ARG TRP HIS ARG TRP ARG LEU n/a n/a
35 3B6S - ARG ARG LYS TRP CIR ARG TRP HIS LEU n/a n/a
36 1JGD - ARG ARG LEU LEU ARG GLY HIS ASN GLN TYR n/a n/a
37 1AGF - GLY GLY LYS LYS ARG TYR LYS LEU n/a n/a
38 2CIK - LYS PRO ILE VAL VAL LEU HIS GLY TYR n/a n/a
39 3LKN - LEU PRO PHE GLU ARG ALA THR ILE MET n/a n/a
40 1HSA - ALA ARG ALA ALA ALA ALA ALA ALA ALA n/a n/a
41 1AGE - GLY GLY LYS LYS LYS TYR ARG LEU n/a n/a
42 2BSS - LYS ARG TRP ILE ILE LEU GLY LEU ASN LYS n/a n/a
43 4JQV - SER GLU LEU GLU ILE LYS ARG TYR n/a n/a
44 3C9N - VAL GLN GLN GLU SER SER PHE VAL MET n/a n/a
45 3X11 - LEU SER SER PRO VAL THR LYS SER PHE n/a n/a
46 1M6O - GLU GLU PHE GLY ARG ALA PHE SER PHE n/a n/a
47 3B3I - ARG ARG LYS TRP CIR ARG TRP HIS LEU n/a n/a
48 3DX8 - GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE n/a n/a
49 3KPL - GLU GLU TYR LEU GLN ALA PHE THR TYR n/a n/a
50 4G9D - LYS ARG TRP ILE ILE LEU GLY LEU ASN LYS n/a n/a
51 3LKR - LEU PRO PHE GLU ARG ALA THR VAL MET n/a n/a
52 3KPP - GLU GLU TYR LEU GLN ALA PHE THR TYR n/a n/a
53 1K5N - GLY ARG PHE ALA ALA ALA ILE ALA LYS n/a n/a
54 1OF2 - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
55 4O2E - SER HIS VAL ALA VAL GLU ASN ALA LEU n/a n/a
56 3BP7 - ILE ARG ALA ALA PRO PRO PRO LEU PHE n/a n/a
57 1XR9 - ILE LEU GLY PRO PRO GLY SER VAL TYR n/a n/a
58 1W0V - ARG ARG LEU PRO ILE PHE SER ARG LEU n/a n/a
59 1E27 - LEU PRO PRO VAL VAL ALA LYS GLU ILE n/a n/a
60 1JGE - GLY ARG PHE ALA ALA ALA ILE ALA LYS n/a n/a
61 3X14 - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
62 1N2R - GLU GLU PHE GLY ARG ALA PHE SER PHE n/a n/a
63 1AGD - GLY GLY LYS LYS LYS TYR LYS LEU n/a n/a
64 3LKO - LEU PRO PHE ASP ARG THR THR ILE MET n/a n/a
65 1SYS - GLU GLU PRO THR VAL ILE LYS LYS TYR n/a n/a
66 3KPM - GLU GLU TYR LEU LYS ALA TRP THR PHE n/a n/a
67 2AXF - ALA PRO GLN PRO ALA PRO GLU ASN ALA TYR n/a n/a
68 4NT6 - GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
69 3BWA - PHE PRO THR LYS ASP VAL ALA LEU n/a n/a
70 4O2F - HIS VAL ALA VAL GLU ASN ALA LEU n/a n/a
71 2H6P - LYS PRO ILE VAL VAL LEU HIS GLY TYR n/a n/a
72 3SKM - PHE LEU ARG GLY ARG ALA TYR VAL LEU n/a n/a
73 3UPR - HIS SER ILE THR TYR LEU LEU PRO VAL n/a n/a
74 1SYV - GLU GLU PHE GLY ARG ALA PHE SER PHE n/a n/a
75 3KPQ - GLU GLU TYR LEU LYS ALA TRP THR PHE n/a n/a
76 3LKS - LEU PRO PHE GLU LYS SER THR VAL MET n/a n/a
70% Homology Family (271)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 65 families.
1 4L8B - ALA SER ASN GLU HIS MET GLU THR MET n/a n/a
2 1HOC - ALA SER ASN GLU ASN MET GLU THR MET n/a n/a
3 4HUX - ALA SER ASN GLU ASN MET GLU THR MET n/a n/a
4 3CH1 - GLU GLY PRO ARG ASN GLN ASP TRP LEU n/a n/a
5 4HV8 - ALA SER ASN GLU ASN ILE GLU THR MET n/a n/a
6 1WBX - SER GLN LEU LYS ASN ASN ALA LYS GLU ILE n/a n/a
7 4HUV - ALA SER ASN GLU ASN TRP GLU THR MET n/a n/a
8 1INQ ic50 = 539 nM SER SER VAL VAL GLY VAL TRP TYR LEU n/a n/a
9 2ZOK - ABA SER LEU TRP ASN GLY PRO HIS LEU n/a n/a
10 1YN7 - SER SER LEU GLU ASN PHE ALA ALA TYR VAL n/a n/a
11 4HUU - ALA SER ASN GLU ASN ILE GLU THR MET n/a n/a
12 4QRT - GLU LEU ASN ARG LYS MET ILE TYR MET n/a n/a
13 2X4O - LYS LEU THR PRO LEU CYS VAL THR LEU n/a n/a
14 2C7U Kd = 100 nM SER LEU PHE ASN THR ILE ALA VAL LEU n/a n/a
15 1EEY - ILE LEU SER ALA LEU VAL GLY ILE VAL n/a n/a
16 1HHJ - ILE LEU LYS GLU PRO VAL HIS GLY VAL n/a n/a
17 2GTW - LEU ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
18 3GSV Kd = 57.5 uM ASN LEU VAL PRO GLN VAL ALA THR VAL n/a n/a
19 1QR1 - ILE ILE SER ALA VAL VAL GLY ILE LEU n/a n/a
20 3O3B - GLU LEU ALA GIC 3AZ LEU THR VAL n/a n/a
21 3D25 ic50 = 22 nM VAL LEU HIS ASP ASP LEU LEU GLU ALA n/a n/a
22 3BH9 ic50 = 116.9 nM ARG THR TYR SEP GLY PRO MET ASN LYS VAL n/a n/a
23 3OXS - PHE LEU PRO SER ASP PHE PHE PRO SER VAL n/a n/a
24 2V2X Kd = 5.2 uM SER LEU PHE ASN THR VAL ALA THR LEU n/a n/a
25 4JFO Kd = 140 uM ALA LEU ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
26 4GKS - PHE LEU THR GLY ILE GLY ILE ILE THR VAL n/a n/a
27 1T20 - SER LEU TYR ASN THR ILE ALA THR LEU n/a n/a
28 3GIV - SER LEU PHE ASN THR VAL ALA THR LEU TYR n/a n/a
29 1I1Y - TYR LEU LYS GLU PRO VAL HIS GLY VAL n/a n/a
30 3VXP - ARG TYR PRO LEU THR LEU GLY TRP CYS PHE n/a n/a
31 3PWL Kd = 140 uM LEU GLY TYR GLY PHE VAL ASN TYR ILE n/a n/a
32 3FT3 ic50 = 44 nM VAL LEU HIS ASP ASP LEU LEU GLU ALA n/a n/a
33 3UTQ - ALA LEU TRP GLY PRO ASP PRO ALA ALA ALA n/a n/a
34 4F7P - PHE TYR ARG TYR GLY PHE VAL ALA ASN PHE n/a n/a
35 3RL1 - ALA ILE PHE GLN SER SER MET THR LYS n/a n/a
36 2VLL - GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
37 1T1Z - ALA LEU TYR ASN THR ALA ALA ALA LEU n/a n/a
38 3FQT - GLY LEU LEU GLY SER PRO VAL ARG ALA n/a n/a
39 3GSQ - ASN LEU VAL PRO SER VAL ALA THR VAL n/a n/a
40 4NQX - CYS THR GLU LEU LYS LEU ASN ASP TYR n/a n/a
41 3VXN - ARG TYR PRO LEU THR PHE GLY TRP CYS PHE n/a n/a
42 3QFD Kd = 68 uM ALA ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
43 3O3A - BAL LEU ALA GIC 3AZ LEU THR VAL n/a n/a
44 2X4N - LYS ILE LEU GLY PRV VAL PHE PRQ VAL n/a n/a
45 4F7T - ARG TYR GLY PHE VAL ALA ASN PHE n/a n/a
46 1DUZ - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
47 3H7B Kd = 41 uM MET LEU TRP GLY TYR LEU GLN TYR VAL n/a n/a
48 3WL9 - ASN TYR THR PRO GLY PRO GLY ILE ARG PHE n/a n/a
49 4JFP - GLU LEU ALA ALA ILE GLY ILE LEU THR VAL n/a n/a
50 3FQW - ARG VAL ALA SER PRO THR SER GLY VAL n/a n/a
51 1TVB - ILE THR ASP GLN VAL PRO PHE SER VAL n/a n/a
52 1T1W - SER LEU PHE ASN THR ILE ALA VAL LEU n/a n/a
53 3GSU Kd = 58.2 uM ASN LEU VAL PRO THR VAL ALA THR VAL n/a n/a
54 3MYJ - TYR MET PHE PRO ASN ALA PRO TYR LEU n/a n/a
55 1Q94 - ALA ILE PHE GLN SER SER MET THR LYS n/a n/a
56 3H9H Kd = 5.4 uM MET LEU TRP GLY TYR LEU GLN TYR VAL n/a n/a
57 3O3E - BAL LEU ALA TIG 3AZ LEU THR VAL n/a n/a
58 3IXA Kd = 9.8 uM LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
59 4I4W - ILE LEU ALA LYS PHE LEU HIS ARG LEU n/a n/a
60 3FT2 ic50 = 44 nM VAL LEU CIR ASP ASP LEU LEU GLU ALA n/a n/a
61 2GT9 - GLU ALA ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
62 2X4R - ASN LEU VAL PRO MET VAL ALA THR VAL n/a n/a
63 2CLR - MET LEU LEU SER VAL PRO LEU LEU LEU GLY n/a n/a
64 4HWZ - ALA ILE PHE GLN SER SER MET THR LYS n/a n/a
65 1T22 - SER LEU TYR ASN THR VAL ALA THR LEU n/a n/a
66 1I4F - GLY VAL TYR ASP GLY ARG GLU HIS THR VAL n/a n/a
67 3PWJ Kd = 70 uM LEU LEU TYR GLY PHE VAL ASN TYR VAL n/a n/a
68 3NFN - ARG TYR PRO LEU THR PHE GLY TRP CYS PHE n/a n/a
69 3FQU - GLY LEU LEU GLY SEP PRO VAL ARG ALA n/a n/a
70 1JF1 - GLU LEU ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
71 1HHK - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
72 3FQN - TYR LEU ASP SER GLY ILE HIS SER GLY ALA n/a n/a
73 3BH8 ic50 = 11.2 nM ARG GLN ALA SEP ILE GLU LEU PRO SER MET n/a n/a
74 3BGM ic50 = 32.5 nM ARG GLN ALA SEP LEU SER ILE SER VAL n/a n/a
75 3O3D - GLU LEU ALA TIG 3AZ LEU THR VAL n/a n/a
76 3PWN Kd = 48 uM LEU LEU TYR GLY PHE VAL ASN TYR ILE n/a n/a
77 3BHB ic50 = 3.4 nM LYS MET ASP SEP PHE LEU ASP MET GLN LEU n/a n/a
78 1S9W - SER LEU LEU MET TRP ILE THR GLN CYS n/a n/a
79 4HX1 - SER VAL TYR ASP PHE PHE VAL TRP LEU n/a n/a
80 3MGT - LYS LEU TYR GLN ASN PRO THR THR TYR ILE n/a n/a
81 3MGO - ARG LEU TYR GLN ASN PRO THR THR TYR ILE n/a n/a
82 3FQX - ARG VAL ALA SEP PRO THR SER GLY VAL n/a n/a
83 1S9Y - SER LEU LEU MET TRP ILE THR GLN SER n/a n/a
84 1I7R - PHE ALA PRO GLY PHE PHE PRO TYR LEU n/a n/a
85 2AV7 - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
86 1X7Q - LYS THR PHE PRO PRO THR GLU PRO LYS n/a n/a
87 1S8D - SER LEU ALA ASN THR VAL ALA THR LEU n/a n/a
88 4F7M - LEU TYR ALA SER PRO GLN LEU GLU GLY PHE n/a n/a
89 3WLB - ASN TYR THR PRO GLY PRO GLY THR ARG PHE n/a n/a
90 3OX8 - PHE LEU PRO SER ASP PHE PHE PRO SER VAL n/a n/a
91 3GSX - ASN LEU VAL PRO MET VAL ALA VAL VAL n/a n/a
92 3RL2 - GLN VAL PRO LEU ARG PRO MET THR TYR LYS n/a n/a
93 2GUO - ALA ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
94 1T1X - SER LEU TYR LEU THR VAL ALA THR LEU n/a n/a
95 4JFQ - GLU LEU ALA GLY ILE GLY ILE ALA THR VAL n/a n/a
96 1DUY - LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
97 1I7U - ALA LEU TRP GLY PHE VAL PRO VAL LEU n/a n/a
98 1S9X - SER LEU LEU MET TRP ILE THR GLN ALA n/a n/a
99 3GSO Kd = 27.7 uM ASN LEU VAL PRO MET VAL ALA THR VAL n/a n/a
100 2X4P - MSE ILE LEU GLY PRV VAL PHE PRQ VAL n/a n/a
101 3FT4 ic50 = 1171 nM VAL LEU ARG ASP ASP LEU LEU GLU ALA n/a n/a
102 3HPJ - ARG MET PHE PRO ASN ALA PRO TYR LEU n/a n/a
103 3KLA Kd = 31.1 uM SER LEU LEU MET TRP ILE THR GLN LEU n/a n/a
104 1HHI - GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
105 1JHT - ALA LEU GLY ILE GLY ILE LEU THR VAL n/a n/a
106 4K7F - VAL CYS TRP GLY GLU LEU MET ASN LEU n/a n/a
107 2V2W Kd = 2.2 uM SER LEU TYR ASN THR VAL ALA THR LEU n/a n/a
108 2X4U - ILE LEU LYS GLU PRO VAL HIS GLY VAL n/a n/a
109 3I6L - GLN PHE LYS ASP ASN VAL ILE LEU LEU n/a n/a
110 1QVO - GLN VAL PRO LEU ARG PRO MET THR TYR LYS n/a n/a
111 2GIT - LEU LEU PHE GLY LYS PRO VAL TYR VAL n/a n/a
112 4NQV - CYS THR GLU LEU LYS LEU SER ASP TYR n/a n/a
113 2X70 - LYS ILE LEU GLY PRV VAL PHE PRQ VAL n/a n/a
114 1T21 - SER LEU TYR ASN THR VAL ALA THR LEU n/a n/a
115 3BO8 - GLU ALA ASP PRO THR GLY HIS SER TYR n/a n/a
116 2GTZ - ALA LEU GLY ILE GLY ILE LEU THR VAL n/a n/a
117 3OXR - PHE LEU PRO SER ASP PHE PHE PRO SER VAL n/a n/a
118 2AV1 - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
119 3GSR Kd = 60.2 uM ASN LEU VAL PRO VAL VAL ALA THR VAL n/a n/a
120 1T1Y - SER LEU TYR ASN VAL VAL ALA THR LEU n/a n/a
121 1EEZ - ILE LEU SER ALA LEU VAL GLY ILE LEU n/a n/a
122 1TVH - ILE MET ASP GLN VAL PRO PHE SER VAL n/a n/a
123 1QEW - PHE LEU TRP GLY PRO ARG ALA LEU VAL n/a n/a
124 1HSB - ALA VAL ALA n/a n/a
125 3REW Kd = 28.8 uM CYS LEU GLY GLY LEU LEU THR MET VAL n/a n/a
126 2HN7 ic50 = 31 nM ALA ILE MET PRO ALA ARG PHE TYR PRO LYS n/a n/a
127 3FQR - TYR LEU ASP SEP GLY ILE HIS SER GLY ALA n/a n/a
128 3I6G - GLY LEU MET TRP LEU SER TYR PHE VAL n/a n/a
129 4QRS - GLU LEU LYS ARG LYS MET ILE TYR MET n/a n/a
130 3X13 - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
131 3VRI - ARG VAL ALA GLN LEU GLU GLN VAL TYR ILE n/a n/a
132 3LKP - LEU PRO PHE ASP LYS SER THR ILE MET n/a n/a
133 3LV3 - SER ARG ARG TRP ARG ARG TRP ASN ARG n/a n/a
134 1A9E - LEU PRO PRO LEU ASP ILE THR PRO TYR n/a n/a
135 1UXW - ARG ARG ARG TRP ARG ARG LEU THR VAL n/a n/a
136 1W0W - ARG ARG LEU PRO ILE PHE SER ARG LEU n/a n/a
137 1XR8 - LEU GLU LYS ALA ARG GLY SER THR TYR n/a n/a
138 4G8I - LYS ARG TRP ILE ILE MET GLY LEU ASN LYS n/a n/a
139 1AGC - GLY GLY LYS LYS LYS TYR GLN LEU n/a n/a
140 1A1M - THR PRO TYR ASP ILE ASN GLN MET LEU n/a n/a
141 3SKO - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
142 3BXN - ILE ARG ALA ALA PRO PRO PRO LEU PHE n/a n/a
143 1A1O - LYS PRO ILE VAL GLN TYR ASP ASN PHE n/a n/a
144 2BVP - ILE SER PRO ARG THR LEU ASP ALA TRP n/a n/a
145 3DX7 - GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE n/a n/a
146 1M05 - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
147 1UXS - ARG ARG ARG TRP ARG ARG LEU THR VAL n/a n/a
148 2BSR - ARG ARG ILE TYR ASP LEU ILE GLU LEU n/a n/a
149 3VRJ - LEU THR THR LYS LEU THR ASN THR ASN ILE n/a n/a
150 2BST - SER ARG TYR TRP ALA ILE ARG THR ARG n/a n/a
151 3BP4 - ILE ARG ALA ALA PRO PRO PRO LEU PHE n/a n/a
152 3X12 - LEU SER SER PRO VAL THR LYS SER PHE n/a n/a
153 4O2C ic50 = 10 nM ACE SER HIS VAL ALA VAL GLU ASN ALA LEU n/a n/a
154 1AGB - GLY GLY ARG LYS LYS TYR LYS LEU n/a n/a
155 3LKQ - LEU PRO PHE ASP LYS THR THR ILE MET n/a n/a
156 2AXG - ALA PRO GLN PRO ALA PRO GLU ASN ALA TYR n/a n/a
157 1A1N - VAL PRO LEU ARG PRO MET THR TYR n/a n/a
158 1OGT - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
159 3KPO - GLU GLU TYR LEU LYS ALA TRP THR PHE n/a n/a
160 3DX6 - GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE n/a n/a
161 2A83 - ARG ARG ARG TRP HIS ARG TRP ARG LEU n/a n/a
162 3B6S - ARG ARG LYS TRP CIR ARG TRP HIS LEU n/a n/a
163 1JGD - ARG ARG LEU LEU ARG GLY HIS ASN GLN TYR n/a n/a
164 1AGF - GLY GLY LYS LYS ARG TYR LYS LEU n/a n/a
165 2CIK - LYS PRO ILE VAL VAL LEU HIS GLY TYR n/a n/a
166 3LKN - LEU PRO PHE GLU ARG ALA THR ILE MET n/a n/a
167 1HSA - ALA ARG ALA ALA ALA ALA ALA ALA ALA n/a n/a
168 1AGE - GLY GLY LYS LYS LYS TYR ARG LEU n/a n/a
169 2BSS - LYS ARG TRP ILE ILE LEU GLY LEU ASN LYS n/a n/a
170 4JQV - SER GLU LEU GLU ILE LYS ARG TYR n/a n/a
171 3C9N - VAL GLN GLN GLU SER SER PHE VAL MET n/a n/a
172 3X11 - LEU SER SER PRO VAL THR LYS SER PHE n/a n/a
173 1M6O - GLU GLU PHE GLY ARG ALA PHE SER PHE n/a n/a
174 3B3I - ARG ARG LYS TRP CIR ARG TRP HIS LEU n/a n/a
175 3DX8 - GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE n/a n/a
176 3KPL - GLU GLU TYR LEU GLN ALA PHE THR TYR n/a n/a
177 4G9D - LYS ARG TRP ILE ILE LEU GLY LEU ASN LYS n/a n/a
178 3LKR - LEU PRO PHE GLU ARG ALA THR VAL MET n/a n/a
179 3KPP - GLU GLU TYR LEU GLN ALA PHE THR TYR n/a n/a
180 1K5N - GLY ARG PHE ALA ALA ALA ILE ALA LYS n/a n/a
181 1OF2 - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
182 4O2E - SER HIS VAL ALA VAL GLU ASN ALA LEU n/a n/a
183 3BP7 - ILE ARG ALA ALA PRO PRO PRO LEU PHE n/a n/a
184 1XR9 - ILE LEU GLY PRO PRO GLY SER VAL TYR n/a n/a
185 1W0V - ARG ARG LEU PRO ILE PHE SER ARG LEU n/a n/a
186 1E27 - LEU PRO PRO VAL VAL ALA LYS GLU ILE n/a n/a
187 1JGE - GLY ARG PHE ALA ALA ALA ILE ALA LYS n/a n/a
188 3X14 - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
189 1N2R - GLU GLU PHE GLY ARG ALA PHE SER PHE n/a n/a
190 1AGD - GLY GLY LYS LYS LYS TYR LYS LEU n/a n/a
191 3LKO - LEU PRO PHE ASP ARG THR THR ILE MET n/a n/a
192 1SYS - GLU GLU PRO THR VAL ILE LYS LYS TYR n/a n/a
193 3KPM - GLU GLU TYR LEU LYS ALA TRP THR PHE n/a n/a
194 2AXF - ALA PRO GLN PRO ALA PRO GLU ASN ALA TYR n/a n/a
195 4NT6 - GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
196 3BWA - PHE PRO THR LYS ASP VAL ALA LEU n/a n/a
197 4O2F - HIS VAL ALA VAL GLU ASN ALA LEU n/a n/a
198 2H6P - LYS PRO ILE VAL VAL LEU HIS GLY TYR n/a n/a
199 3SKM - PHE LEU ARG GLY ARG ALA TYR VAL LEU n/a n/a
200 3UPR - HIS SER ILE THR TYR LEU LEU PRO VAL n/a n/a
201 1SYV - GLU GLU PHE GLY ARG ALA PHE SER PHE n/a n/a
202 3KPQ - GLU GLU TYR LEU LYS ALA TRP THR PHE n/a n/a
203 3LKS - LEU PRO PHE GLU LYS SER THR VAL MET n/a n/a
204 1WBZ - SER SER TYR ARG ARG PRO VAL GLY ILE n/a n/a
205 1NAN - ILE ASN PHE ASP PHE ASN THR ILE n/a n/a
206 1VAD - SER ARG ASP HIS SER ARG THR PRO MET n/a n/a
207 2VAA - ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
208 1FZM Kd = 20 nM ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
209 2VAB - PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
210 2CLV - SER GLN TYR TYR TYR ASN SER LEU n/a n/a
211 1KJ3 - LYS VAL ILE THR PHE ILE ASP LEU n/a n/a
212 4PV8 - ARG ABA PHE ILE PHE ALA ASN ILE n/a n/a
213 2ZSV - ARG ABA GLN ILE PHE ALA ASN ILE n/a n/a
214 1RJY - SER SER ILE GLU PHE ALA ARG LEU n/a n/a
215 1FZJ Kd = 8 nM ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
216 1G7P Kd = 90 nM SER ARG ASP HIS SER ARG THR PRO MET n/a n/a
217 2CLZ - ILE ASN PHE ASP PHE ASN THR ILE n/a n/a
218 1KPU - ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
219 1T0N - SER SER ILE GLU PHE ALA ARG LEU n/a n/a
220 1RK1 - SER GLU ILE GLU PHE ALA ARG LEU n/a n/a
221 3PAB Kd = 20 uM GLU ILE ILE ASN PHE GLU LYS LEU n/a n/a
222 1G7Q Kd = 877 nM SER ALA PRO ASP THR ARG PRO ALA n/a n/a
223 1FZO Kd = 13 nM PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
224 3P9L Kd = 6 uM SER ILE ILE ASN PHE GLU LYS LEU n/a n/a
225 1T0M - SER SER ILE GLU PHE ALA ARG LEU n/a n/a
226 4HS3 - ALA VAL TYR ASN PHE ALA THR MET n/a n/a
227 1FZK Kd = 4 nM PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
228 4PV9 - ARG ABA VAL ILE PHE ALA ASN ILE n/a n/a
229 1KPV - PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
230 1OSZ - ARG GLY TYR LEU TYR GLN GLY LEU n/a n/a
231 1LEK Kd = 1.3 nM GLU GLN TYR LYS PHE TYR SER VAL n/a n/a
232 1LK2 ic50 = 12 uM GLY ASN TYR SER PHE TYR ALA LEU n/a n/a
233 1LEG Kd = 11.1 nM GLU GLN TYR LYS PHE TYR SER VAL n/a n/a
234 1KBG - ARG GLY TYR VAL TYR ESC GLY LEU GAL GLA n/a n/a
235 3P9M Kd = 10 uM SER ILE ILE GLY PHE GLU LYS LEU n/a n/a
236 1VAC - SER ILE ILE ASN PHE GLU LYS LEU n/a n/a
237 1ZT1 - PHE GLU ALA ASN GLY ASN LEU ILE n/a n/a
238 1K8D - ILE LEU MET GLU HIS ILE HIS LYS LEU n/a n/a
239 1KJM - ALA GLN PHE SER ALA SER ALA SER ARG n/a n/a
240 3PWU - ILE PRO ALA TYR GLY VAL LEU THR ILE n/a n/a
241 3CC5 - LYS VAL PRO ARG ASN GLN ASP TRP LEU n/a n/a
242 1YN6 - SER SER LEU GLU ASN PHE ARG ALA TYR VAL n/a n/a
243 1JUF ic50 = 1400 nM SER SER VAL ILE GLY VAL TRP TYR LEU n/a n/a
244 1JPG - PHE GLN PRO GLN ASN GLY GLN PHE ILE n/a n/a
245 3CPL - ALA SER ASN GLU ASN ALA GLU THR MET n/a n/a
246 1LD9 - TYR PRO ASN VAL ASN ILE HIS ASN PHE n/a n/a
247 1WBY - SER SER LEU GLU ASN PHE ARG ALA TYR VAL n/a n/a
248 1S7T - LYS ALA VAL PHE ASN PHE ALA THR MET n/a n/a
249 1S7Q - LYS ALA VAL TYR ASN PHE ALA THR MET n/a n/a
250 3E6H - ILE GLY PRO GLY ARG ALA PHE TYR THR ILE n/a n/a
251 3ECB - ARG GLY PRO GLY ARG ALA PHE VAL THR ILE n/a n/a
252 3E6F - ILE GLY PRO GLY ARG ALA PHE TYR ALA n/a n/a
253 3VJ6 Kd = 17 uM ALA MET ALA PRO ARG THR LEU LEU LEU n/a n/a
254 1KJV - ASN PRO ARG ALA MET GLN ALA LEU LEU n/a n/a
255 1YDP - ARG ILE ILE PRO ARG HIS LEU GLN LEU n/a n/a
256 3KYN - LYS GLY PRO PRO ALA ALA LEU THR LEU n/a n/a
257 3KYO - LYS LEU PRO ALA GLN PHE TYR ILE LEU n/a n/a
258 3RWG ic50 = 2.8 nM MET HIS PRO ALA GLN THR SER GLN TRP n/a n/a
259 3RWI ic50 = 116 nM GLY SER HIS LEU GLU VAL GLN GLY TYR TRP n/a n/a
260 3RWE ic50 = 43 nM PHE GLN TRP MET GLY TYR GLU LEU TRP n/a n/a
261 3RWC ic50 = 7.6 nM ILE ARG TYR PRO LYS THR PHE GLY TRP n/a n/a
262 1BII - ARG GLY PRO GLY ARG ALA PHE VAL THR ILE n/a n/a
263 3FOM - ILE GLN GLN SER ILE GLU ARG ILE n/a n/a
264 3FON - VAL ASN ASP ILE PHE GLU ALA ILE n/a n/a
265 1S7U - LYS ALA VAL TYR ASN PHE ALA THR MET n/a n/a
266 1S7V - LYS ALA VAL TYR ASN LEU ALA THR MET n/a n/a
267 3BZF - VAL MET ALA PRO ARG ALA LEU LEU LEU n/a n/a
268 3BZE - VAL MET ALA PRO ARG THR LEU PHE LEU n/a n/a
269 4QRQ Kd = 2.48 uM HIS SER LYS LYS LYS CYS ASP GLU LEU n/a n/a
270 3QQ4 - ALA THR ALA ALA ALA THR GLU ALA TYR n/a n/a
271 1MHC - FME TYR PHE ILE ASN ILE LEU THR LEU n/a n/a
50% Homology Family (275)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 44 families.
1 4L8B - ALA SER ASN GLU HIS MET GLU THR MET n/a n/a
2 1HOC - ALA SER ASN GLU ASN MET GLU THR MET n/a n/a
3 4HUX - ALA SER ASN GLU ASN MET GLU THR MET n/a n/a
4 3CH1 - GLU GLY PRO ARG ASN GLN ASP TRP LEU n/a n/a
5 4HV8 - ALA SER ASN GLU ASN ILE GLU THR MET n/a n/a
6 1WBX - SER GLN LEU LYS ASN ASN ALA LYS GLU ILE n/a n/a
7 4HUV - ALA SER ASN GLU ASN TRP GLU THR MET n/a n/a
8 1INQ ic50 = 539 nM SER SER VAL VAL GLY VAL TRP TYR LEU n/a n/a
9 2ZOK - ABA SER LEU TRP ASN GLY PRO HIS LEU n/a n/a
10 1YN7 - SER SER LEU GLU ASN PHE ALA ALA TYR VAL n/a n/a
11 4HUU - ALA SER ASN GLU ASN ILE GLU THR MET n/a n/a
12 4QRT - GLU LEU ASN ARG LYS MET ILE TYR MET n/a n/a
13 2X4O - LYS LEU THR PRO LEU CYS VAL THR LEU n/a n/a
14 2C7U Kd = 100 nM SER LEU PHE ASN THR ILE ALA VAL LEU n/a n/a
15 1EEY - ILE LEU SER ALA LEU VAL GLY ILE VAL n/a n/a
16 1HHJ - ILE LEU LYS GLU PRO VAL HIS GLY VAL n/a n/a
17 2GTW - LEU ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
18 3GSV Kd = 57.5 uM ASN LEU VAL PRO GLN VAL ALA THR VAL n/a n/a
19 1QR1 - ILE ILE SER ALA VAL VAL GLY ILE LEU n/a n/a
20 3O3B - GLU LEU ALA GIC 3AZ LEU THR VAL n/a n/a
21 3D25 ic50 = 22 nM VAL LEU HIS ASP ASP LEU LEU GLU ALA n/a n/a
22 3BH9 ic50 = 116.9 nM ARG THR TYR SEP GLY PRO MET ASN LYS VAL n/a n/a
23 3OXS - PHE LEU PRO SER ASP PHE PHE PRO SER VAL n/a n/a
24 2V2X Kd = 5.2 uM SER LEU PHE ASN THR VAL ALA THR LEU n/a n/a
25 4JFO Kd = 140 uM ALA LEU ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
26 4GKS - PHE LEU THR GLY ILE GLY ILE ILE THR VAL n/a n/a
27 1T20 - SER LEU TYR ASN THR ILE ALA THR LEU n/a n/a
28 3GIV - SER LEU PHE ASN THR VAL ALA THR LEU TYR n/a n/a
29 1I1Y - TYR LEU LYS GLU PRO VAL HIS GLY VAL n/a n/a
30 3VXP - ARG TYR PRO LEU THR LEU GLY TRP CYS PHE n/a n/a
31 3PWL Kd = 140 uM LEU GLY TYR GLY PHE VAL ASN TYR ILE n/a n/a
32 3FT3 ic50 = 44 nM VAL LEU HIS ASP ASP LEU LEU GLU ALA n/a n/a
33 3UTQ - ALA LEU TRP GLY PRO ASP PRO ALA ALA ALA n/a n/a
34 4F7P - PHE TYR ARG TYR GLY PHE VAL ALA ASN PHE n/a n/a
35 3RL1 - ALA ILE PHE GLN SER SER MET THR LYS n/a n/a
36 2VLL - GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
37 1T1Z - ALA LEU TYR ASN THR ALA ALA ALA LEU n/a n/a
38 3FQT - GLY LEU LEU GLY SER PRO VAL ARG ALA n/a n/a
39 3GSQ - ASN LEU VAL PRO SER VAL ALA THR VAL n/a n/a
40 4NQX - CYS THR GLU LEU LYS LEU ASN ASP TYR n/a n/a
41 3VXN - ARG TYR PRO LEU THR PHE GLY TRP CYS PHE n/a n/a
42 3QFD Kd = 68 uM ALA ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
43 3O3A - BAL LEU ALA GIC 3AZ LEU THR VAL n/a n/a
44 2X4N - LYS ILE LEU GLY PRV VAL PHE PRQ VAL n/a n/a
45 4F7T - ARG TYR GLY PHE VAL ALA ASN PHE n/a n/a
46 1DUZ - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
47 3H7B Kd = 41 uM MET LEU TRP GLY TYR LEU GLN TYR VAL n/a n/a
48 3WL9 - ASN TYR THR PRO GLY PRO GLY ILE ARG PHE n/a n/a
49 4JFP - GLU LEU ALA ALA ILE GLY ILE LEU THR VAL n/a n/a
50 3FQW - ARG VAL ALA SER PRO THR SER GLY VAL n/a n/a
51 1TVB - ILE THR ASP GLN VAL PRO PHE SER VAL n/a n/a
52 1T1W - SER LEU PHE ASN THR ILE ALA VAL LEU n/a n/a
53 3GSU Kd = 58.2 uM ASN LEU VAL PRO THR VAL ALA THR VAL n/a n/a
54 3MYJ - TYR MET PHE PRO ASN ALA PRO TYR LEU n/a n/a
55 1Q94 - ALA ILE PHE GLN SER SER MET THR LYS n/a n/a
56 3H9H Kd = 5.4 uM MET LEU TRP GLY TYR LEU GLN TYR VAL n/a n/a
57 3O3E - BAL LEU ALA TIG 3AZ LEU THR VAL n/a n/a
58 3IXA Kd = 9.8 uM LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
59 4I4W - ILE LEU ALA LYS PHE LEU HIS ARG LEU n/a n/a
60 3FT2 ic50 = 44 nM VAL LEU CIR ASP ASP LEU LEU GLU ALA n/a n/a
61 2GT9 - GLU ALA ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
62 2X4R - ASN LEU VAL PRO MET VAL ALA THR VAL n/a n/a
63 2CLR - MET LEU LEU SER VAL PRO LEU LEU LEU GLY n/a n/a
64 4HWZ - ALA ILE PHE GLN SER SER MET THR LYS n/a n/a
65 1T22 - SER LEU TYR ASN THR VAL ALA THR LEU n/a n/a
66 1I4F - GLY VAL TYR ASP GLY ARG GLU HIS THR VAL n/a n/a
67 3PWJ Kd = 70 uM LEU LEU TYR GLY PHE VAL ASN TYR VAL n/a n/a
68 3NFN - ARG TYR PRO LEU THR PHE GLY TRP CYS PHE n/a n/a
69 3FQU - GLY LEU LEU GLY SEP PRO VAL ARG ALA n/a n/a
70 1JF1 - GLU LEU ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
71 1HHK - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
72 3FQN - TYR LEU ASP SER GLY ILE HIS SER GLY ALA n/a n/a
73 3BH8 ic50 = 11.2 nM ARG GLN ALA SEP ILE GLU LEU PRO SER MET n/a n/a
74 3BGM ic50 = 32.5 nM ARG GLN ALA SEP LEU SER ILE SER VAL n/a n/a
75 3O3D - GLU LEU ALA TIG 3AZ LEU THR VAL n/a n/a
76 3PWN Kd = 48 uM LEU LEU TYR GLY PHE VAL ASN TYR ILE n/a n/a
77 3BHB ic50 = 3.4 nM LYS MET ASP SEP PHE LEU ASP MET GLN LEU n/a n/a
78 1S9W - SER LEU LEU MET TRP ILE THR GLN CYS n/a n/a
79 4HX1 - SER VAL TYR ASP PHE PHE VAL TRP LEU n/a n/a
80 3MGT - LYS LEU TYR GLN ASN PRO THR THR TYR ILE n/a n/a
81 3MGO - ARG LEU TYR GLN ASN PRO THR THR TYR ILE n/a n/a
82 3FQX - ARG VAL ALA SEP PRO THR SER GLY VAL n/a n/a
83 1S9Y - SER LEU LEU MET TRP ILE THR GLN SER n/a n/a
84 1I7R - PHE ALA PRO GLY PHE PHE PRO TYR LEU n/a n/a
85 2AV7 - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
86 1X7Q - LYS THR PHE PRO PRO THR GLU PRO LYS n/a n/a
87 1S8D - SER LEU ALA ASN THR VAL ALA THR LEU n/a n/a
88 4F7M - LEU TYR ALA SER PRO GLN LEU GLU GLY PHE n/a n/a
89 3WLB - ASN TYR THR PRO GLY PRO GLY THR ARG PHE n/a n/a
90 3OX8 - PHE LEU PRO SER ASP PHE PHE PRO SER VAL n/a n/a
91 3GSX - ASN LEU VAL PRO MET VAL ALA VAL VAL n/a n/a
92 3RL2 - GLN VAL PRO LEU ARG PRO MET THR TYR LYS n/a n/a
93 2GUO - ALA ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
94 1T1X - SER LEU TYR LEU THR VAL ALA THR LEU n/a n/a
95 4JFQ - GLU LEU ALA GLY ILE GLY ILE ALA THR VAL n/a n/a
96 1DUY - LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
97 1I7U - ALA LEU TRP GLY PHE VAL PRO VAL LEU n/a n/a
98 1S9X - SER LEU LEU MET TRP ILE THR GLN ALA n/a n/a
99 3GSO Kd = 27.7 uM ASN LEU VAL PRO MET VAL ALA THR VAL n/a n/a
100 2X4P - MSE ILE LEU GLY PRV VAL PHE PRQ VAL n/a n/a
101 3FT4 ic50 = 1171 nM VAL LEU ARG ASP ASP LEU LEU GLU ALA n/a n/a
102 3HPJ - ARG MET PHE PRO ASN ALA PRO TYR LEU n/a n/a
103 3KLA Kd = 31.1 uM SER LEU LEU MET TRP ILE THR GLN LEU n/a n/a
104 1HHI - GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
105 1JHT - ALA LEU GLY ILE GLY ILE LEU THR VAL n/a n/a
106 4K7F - VAL CYS TRP GLY GLU LEU MET ASN LEU n/a n/a
107 2V2W Kd = 2.2 uM SER LEU TYR ASN THR VAL ALA THR LEU n/a n/a
108 2X4U - ILE LEU LYS GLU PRO VAL HIS GLY VAL n/a n/a
109 3I6L - GLN PHE LYS ASP ASN VAL ILE LEU LEU n/a n/a
110 1QVO - GLN VAL PRO LEU ARG PRO MET THR TYR LYS n/a n/a
111 2GIT - LEU LEU PHE GLY LYS PRO VAL TYR VAL n/a n/a
112 4NQV - CYS THR GLU LEU LYS LEU SER ASP TYR n/a n/a
113 2X70 - LYS ILE LEU GLY PRV VAL PHE PRQ VAL n/a n/a
114 1T21 - SER LEU TYR ASN THR VAL ALA THR LEU n/a n/a
115 3BO8 - GLU ALA ASP PRO THR GLY HIS SER TYR n/a n/a
116 2GTZ - ALA LEU GLY ILE GLY ILE LEU THR VAL n/a n/a
117 3OXR - PHE LEU PRO SER ASP PHE PHE PRO SER VAL n/a n/a
118 2AV1 - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
119 3GSR Kd = 60.2 uM ASN LEU VAL PRO VAL VAL ALA THR VAL n/a n/a
120 1T1Y - SER LEU TYR ASN VAL VAL ALA THR LEU n/a n/a
121 1EEZ - ILE LEU SER ALA LEU VAL GLY ILE LEU n/a n/a
122 1TVH - ILE MET ASP GLN VAL PRO PHE SER VAL n/a n/a
123 1QEW - PHE LEU TRP GLY PRO ARG ALA LEU VAL n/a n/a
124 1HSB - ALA VAL ALA n/a n/a
125 3REW Kd = 28.8 uM CYS LEU GLY GLY LEU LEU THR MET VAL n/a n/a
126 2HN7 ic50 = 31 nM ALA ILE MET PRO ALA ARG PHE TYR PRO LYS n/a n/a
127 3FQR - TYR LEU ASP SEP GLY ILE HIS SER GLY ALA n/a n/a
128 3I6G - GLY LEU MET TRP LEU SER TYR PHE VAL n/a n/a
129 4QRS - GLU LEU LYS ARG LYS MET ILE TYR MET n/a n/a
130 3X13 - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
131 3VRI - ARG VAL ALA GLN LEU GLU GLN VAL TYR ILE n/a n/a
132 3LKP - LEU PRO PHE ASP LYS SER THR ILE MET n/a n/a
133 3LV3 - SER ARG ARG TRP ARG ARG TRP ASN ARG n/a n/a
134 1A9E - LEU PRO PRO LEU ASP ILE THR PRO TYR n/a n/a
135 1UXW - ARG ARG ARG TRP ARG ARG LEU THR VAL n/a n/a
136 1W0W - ARG ARG LEU PRO ILE PHE SER ARG LEU n/a n/a
137 1XR8 - LEU GLU LYS ALA ARG GLY SER THR TYR n/a n/a
138 4G8I - LYS ARG TRP ILE ILE MET GLY LEU ASN LYS n/a n/a
139 1AGC - GLY GLY LYS LYS LYS TYR GLN LEU n/a n/a
140 1A1M - THR PRO TYR ASP ILE ASN GLN MET LEU n/a n/a
141 3SKO - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
142 3BXN - ILE ARG ALA ALA PRO PRO PRO LEU PHE n/a n/a
143 1A1O - LYS PRO ILE VAL GLN TYR ASP ASN PHE n/a n/a
144 2BVP - ILE SER PRO ARG THR LEU ASP ALA TRP n/a n/a
145 3DX7 - GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE n/a n/a
146 1M05 - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
147 1UXS - ARG ARG ARG TRP ARG ARG LEU THR VAL n/a n/a
148 2BSR - ARG ARG ILE TYR ASP LEU ILE GLU LEU n/a n/a
149 3VRJ - LEU THR THR LYS LEU THR ASN THR ASN ILE n/a n/a
150 2BST - SER ARG TYR TRP ALA ILE ARG THR ARG n/a n/a
151 3BP4 - ILE ARG ALA ALA PRO PRO PRO LEU PHE n/a n/a
152 3X12 - LEU SER SER PRO VAL THR LYS SER PHE n/a n/a
153 4O2C ic50 = 10 nM ACE SER HIS VAL ALA VAL GLU ASN ALA LEU n/a n/a
154 1AGB - GLY GLY ARG LYS LYS TYR LYS LEU n/a n/a
155 3LKQ - LEU PRO PHE ASP LYS THR THR ILE MET n/a n/a
156 2AXG - ALA PRO GLN PRO ALA PRO GLU ASN ALA TYR n/a n/a
157 1A1N - VAL PRO LEU ARG PRO MET THR TYR n/a n/a
158 1OGT - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
159 3KPO - GLU GLU TYR LEU LYS ALA TRP THR PHE n/a n/a
160 3DX6 - GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE n/a n/a
161 2A83 - ARG ARG ARG TRP HIS ARG TRP ARG LEU n/a n/a
162 3B6S - ARG ARG LYS TRP CIR ARG TRP HIS LEU n/a n/a
163 1JGD - ARG ARG LEU LEU ARG GLY HIS ASN GLN TYR n/a n/a
164 1AGF - GLY GLY LYS LYS ARG TYR LYS LEU n/a n/a
165 2CIK - LYS PRO ILE VAL VAL LEU HIS GLY TYR n/a n/a
166 3LKN - LEU PRO PHE GLU ARG ALA THR ILE MET n/a n/a
167 1HSA - ALA ARG ALA ALA ALA ALA ALA ALA ALA n/a n/a
168 1AGE - GLY GLY LYS LYS LYS TYR ARG LEU n/a n/a
169 2BSS - LYS ARG TRP ILE ILE LEU GLY LEU ASN LYS n/a n/a
170 4JQV - SER GLU LEU GLU ILE LYS ARG TYR n/a n/a
171 3C9N - VAL GLN GLN GLU SER SER PHE VAL MET n/a n/a
172 3X11 - LEU SER SER PRO VAL THR LYS SER PHE n/a n/a
173 1M6O - GLU GLU PHE GLY ARG ALA PHE SER PHE n/a n/a
174 3B3I - ARG ARG LYS TRP CIR ARG TRP HIS LEU n/a n/a
175 3DX8 - GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE n/a n/a
176 3KPL - GLU GLU TYR LEU GLN ALA PHE THR TYR n/a n/a
177 4G9D - LYS ARG TRP ILE ILE LEU GLY LEU ASN LYS n/a n/a
178 3LKR - LEU PRO PHE GLU ARG ALA THR VAL MET n/a n/a
179 3KPP - GLU GLU TYR LEU GLN ALA PHE THR TYR n/a n/a
180 1K5N - GLY ARG PHE ALA ALA ALA ILE ALA LYS n/a n/a
181 1OF2 - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
182 4O2E - SER HIS VAL ALA VAL GLU ASN ALA LEU n/a n/a
183 3BP7 - ILE ARG ALA ALA PRO PRO PRO LEU PHE n/a n/a
184 1XR9 - ILE LEU GLY PRO PRO GLY SER VAL TYR n/a n/a
185 1W0V - ARG ARG LEU PRO ILE PHE SER ARG LEU n/a n/a
186 1E27 - LEU PRO PRO VAL VAL ALA LYS GLU ILE n/a n/a
187 1JGE - GLY ARG PHE ALA ALA ALA ILE ALA LYS n/a n/a
188 3X14 - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
189 1N2R - GLU GLU PHE GLY ARG ALA PHE SER PHE n/a n/a
190 1AGD - GLY GLY LYS LYS LYS TYR LYS LEU n/a n/a
191 3LKO - LEU PRO PHE ASP ARG THR THR ILE MET n/a n/a
192 1SYS - GLU GLU PRO THR VAL ILE LYS LYS TYR n/a n/a
193 3KPM - GLU GLU TYR LEU LYS ALA TRP THR PHE n/a n/a
194 2AXF - ALA PRO GLN PRO ALA PRO GLU ASN ALA TYR n/a n/a
195 4NT6 - GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
196 3BWA - PHE PRO THR LYS ASP VAL ALA LEU n/a n/a
197 4O2F - HIS VAL ALA VAL GLU ASN ALA LEU n/a n/a
198 2H6P - LYS PRO ILE VAL VAL LEU HIS GLY TYR n/a n/a
199 3SKM - PHE LEU ARG GLY ARG ALA TYR VAL LEU n/a n/a
200 3UPR - HIS SER ILE THR TYR LEU LEU PRO VAL n/a n/a
201 1SYV - GLU GLU PHE GLY ARG ALA PHE SER PHE n/a n/a
202 3KPQ - GLU GLU TYR LEU LYS ALA TRP THR PHE n/a n/a
203 3LKS - LEU PRO PHE GLU LYS SER THR VAL MET n/a n/a
204 1WBZ - SER SER TYR ARG ARG PRO VAL GLY ILE n/a n/a
205 1NAN - ILE ASN PHE ASP PHE ASN THR ILE n/a n/a
206 1VAD - SER ARG ASP HIS SER ARG THR PRO MET n/a n/a
207 2VAA - ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
208 1FZM Kd = 20 nM ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
209 2VAB - PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
210 2CLV - SER GLN TYR TYR TYR ASN SER LEU n/a n/a
211 1KJ3 - LYS VAL ILE THR PHE ILE ASP LEU n/a n/a
212 4PV8 - ARG ABA PHE ILE PHE ALA ASN ILE n/a n/a
213 2ZSV - ARG ABA GLN ILE PHE ALA ASN ILE n/a n/a
214 1RJY - SER SER ILE GLU PHE ALA ARG LEU n/a n/a
215 1FZJ Kd = 8 nM ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
216 1G7P Kd = 90 nM SER ARG ASP HIS SER ARG THR PRO MET n/a n/a
217 2CLZ - ILE ASN PHE ASP PHE ASN THR ILE n/a n/a
218 1KPU - ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
219 1T0N - SER SER ILE GLU PHE ALA ARG LEU n/a n/a
220 1RK1 - SER GLU ILE GLU PHE ALA ARG LEU n/a n/a
221 3PAB Kd = 20 uM GLU ILE ILE ASN PHE GLU LYS LEU n/a n/a
222 1G7Q Kd = 877 nM SER ALA PRO ASP THR ARG PRO ALA n/a n/a
223 1FZO Kd = 13 nM PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
224 3P9L Kd = 6 uM SER ILE ILE ASN PHE GLU LYS LEU n/a n/a
225 1T0M - SER SER ILE GLU PHE ALA ARG LEU n/a n/a
226 4HS3 - ALA VAL TYR ASN PHE ALA THR MET n/a n/a
227 1FZK Kd = 4 nM PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
228 4PV9 - ARG ABA VAL ILE PHE ALA ASN ILE n/a n/a
229 1KPV - PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
230 1OSZ - ARG GLY TYR LEU TYR GLN GLY LEU n/a n/a
231 1LEK Kd = 1.3 nM GLU GLN TYR LYS PHE TYR SER VAL n/a n/a
232 1LK2 ic50 = 12 uM GLY ASN TYR SER PHE TYR ALA LEU n/a n/a
233 1LEG Kd = 11.1 nM GLU GLN TYR LYS PHE TYR SER VAL n/a n/a
234 1KBG - ARG GLY TYR VAL TYR ESC GLY LEU GAL GLA n/a n/a
235 3P9M Kd = 10 uM SER ILE ILE GLY PHE GLU LYS LEU n/a n/a
236 1VAC - SER ILE ILE ASN PHE GLU LYS LEU n/a n/a
237 1ZT1 - PHE GLU ALA ASN GLY ASN LEU ILE n/a n/a
238 1K8D - ILE LEU MET GLU HIS ILE HIS LYS LEU n/a n/a
239 1KJM - ALA GLN PHE SER ALA SER ALA SER ARG n/a n/a
240 3PWU - ILE PRO ALA TYR GLY VAL LEU THR ILE n/a n/a
241 3CC5 - LYS VAL PRO ARG ASN GLN ASP TRP LEU n/a n/a
242 1YN6 - SER SER LEU GLU ASN PHE ARG ALA TYR VAL n/a n/a
243 1JUF ic50 = 1400 nM SER SER VAL ILE GLY VAL TRP TYR LEU n/a n/a
244 1JPG - PHE GLN PRO GLN ASN GLY GLN PHE ILE n/a n/a
245 3CPL - ALA SER ASN GLU ASN ALA GLU THR MET n/a n/a
246 1LD9 - TYR PRO ASN VAL ASN ILE HIS ASN PHE n/a n/a
247 1WBY - SER SER LEU GLU ASN PHE ARG ALA TYR VAL n/a n/a
248 1S7T - LYS ALA VAL PHE ASN PHE ALA THR MET n/a n/a
249 1S7Q - LYS ALA VAL TYR ASN PHE ALA THR MET n/a n/a
250 4G43 - ILE ASP TRP PHE GLU GLY LYS GLU n/a n/a
251 4E0R - ILE ASP TRP PHE ASP GLY LYS GLU n/a n/a
252 4G42 - ILE ASP TRP PHE ASP GLY LYS ASP n/a n/a
253 3E6H - ILE GLY PRO GLY ARG ALA PHE TYR THR ILE n/a n/a
254 3ECB - ARG GLY PRO GLY ARG ALA PHE VAL THR ILE n/a n/a
255 3E6F - ILE GLY PRO GLY ARG ALA PHE TYR ALA n/a n/a
256 3VJ6 Kd = 17 uM ALA MET ALA PRO ARG THR LEU LEU LEU n/a n/a
257 1KJV - ASN PRO ARG ALA MET GLN ALA LEU LEU n/a n/a
258 1YDP - ARG ILE ILE PRO ARG HIS LEU GLN LEU n/a n/a
259 3KYN - LYS GLY PRO PRO ALA ALA LEU THR LEU n/a n/a
260 3KYO - LYS LEU PRO ALA GLN PHE TYR ILE LEU n/a n/a
261 3RWG ic50 = 2.8 nM MET HIS PRO ALA GLN THR SER GLN TRP n/a n/a
262 3RWI ic50 = 116 nM GLY SER HIS LEU GLU VAL GLN GLY TYR TRP n/a n/a
263 3RWE ic50 = 43 nM PHE GLN TRP MET GLY TYR GLU LEU TRP n/a n/a
264 3RWC ic50 = 7.6 nM ILE ARG TYR PRO LYS THR PHE GLY TRP n/a n/a
265 1BII - ARG GLY PRO GLY ARG ALA PHE VAL THR ILE n/a n/a
266 3FOM - ILE GLN GLN SER ILE GLU ARG ILE n/a n/a
267 3FON - VAL ASN ASP ILE PHE GLU ALA ILE n/a n/a
268 1S7U - LYS ALA VAL TYR ASN PHE ALA THR MET n/a n/a
269 1S7V - LYS ALA VAL TYR ASN LEU ALA THR MET n/a n/a
270 3BZF - VAL MET ALA PRO ARG ALA LEU LEU LEU n/a n/a
271 3BZE - VAL MET ALA PRO ARG THR LEU PHE LEU n/a n/a
272 4QRQ Kd = 2.48 uM HIS SER LYS LYS LYS CYS ASP GLU LEU n/a n/a
273 1TMC - GLU VAL ALA PRO PRO GLU TYR HIS ARG LYS n/a n/a
274 3QQ4 - ALA THR ALA ALA ALA THR GLU ALA TYR n/a n/a
275 1MHC - FME TYR PHE ILE ASN ILE LEU THR LEU n/a n/a
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: VAL PRO LEU ARG PRO MET THR TYR; Similar ligands found: 132
No: Ligand ECFP6 Tc MDL keys Tc
1 VAL PRO LEU ARG PRO MET THR TYR 1 1
2 GLN VAL PRO LEU ARG PRO MET THR TYR LYS 0.723684 0.986486
3 VAL MET ALA PRO ARG THR LEU PHE LEU 0.622517 0.932432
4 ALA MET ALA PRO ARG THR LEU LEU LEU 0.591549 0.905405
5 ARG MET PHE PRO ASN ALA PRO TYR LEU 0.555556 0.923077
6 LEU PRO PHE GLU ARG ALA THR VAL MET 0.539394 0.932432
7 ARG TYR PRO LEU THR PHE GLY TRP CYS PHE 0.530387 0.897436
8 ARG TYR PRO LEU THR LEU GLY TRP CYS PHE 0.530387 0.897436
9 LEU PRO PHE ASP ARG THR THR ILE MET 0.527607 0.933333
10 ALA ILE MET PRO ALA ARG PHE TYR PRO LYS 0.523256 0.907895
11 GLN MET PRO THR GLU ASP GLU TYR 0.522581 0.878378
12 VAL MET ALA PRO ARG ALA LEU LEU LEU 0.520548 0.837838
13 LEU PRO PHE GLU ARG ALA THR ILE MET 0.511765 0.92
14 ILE ARG TYR PRO LYS THR PHE GLY TRP 0.511236 0.848101
15 ARG LEU TYR GLN ASN PRO THR THR TYR ILE 0.508982 0.871795
16 GLN PRO PRO VAL PRO PRO GLN ARG PRO MET 0.503226 0.864865
17 GLY ARG PRO ARG THR THR SER PHE ALA GLU 0.503067 0.853333
18 TYR MET PHE PRO ASN ALA PRO TYR LEU 0.5 0.833333
19 ARG THR TYR SEP GLY PRO MET ASN LYS VAL 0.497238 0.890244
20 ARG PHE PRO LEU THR PHE GLY TRP CYS PHE 0.497238 0.871795
21 ALA ASN SER ARG TYR PRO THR SER ILE ILE 0.496933 0.87013
22 ILE ARG ALA ALA PRO PRO PRO LEU PHE 0.493671 0.826667
23 GLU GLU PRO THR VAL ILE LYS LYS TYR 0.490683 0.8
24 ASN ARG PRO VAL TYR ILE PRO ARG PRO PRO 0.490446 0.878378
25 LYS PRO VAL LEU ARG THR ALA 0.489933 0.863014
26 PRO LYS ARG PRO THR THR LEU ASN LEU PHE 0.488235 0.88
27 THR PRO TYR ASP ILE ASN GLN MET LEU 0.48503 0.855263
28 ARG VAL SER PRO SER THR SER TYR THR PRO 0.482759 0.797297
29 SER SER TYR ARG ARG PRO VAL GLY ILE 0.481707 0.894737
30 ASN PRO ARG ALA MET GLN ALA LEU LEU 0.480519 0.84
31 ILE PRO ALA TYR GLY VAL LEU THR ILE 0.478261 0.8
32 SER ALA PRO ASP THR ARG PRO ALA 0.476821 0.828947
33 DPN PRO DAR DTH NH2 0.475177 0.808219
34 ALA ASN SER ARG TRP PRO THR THR ARG LEU 0.474684 0.881579
35 PHE ASN ARG PRO VAL 0.472603 0.8
36 DTY ILE ARG LEU LPD 0.470199 0.851351
37 LEU GLN ARG VAL LEU SEP ALA PRO PHE 0.469136 0.765432
38 ASN TYR THR PRO GLY PRO GLY THR ARG PHE 0.468208 0.87013
39 LEU PRO PHE GLU LYS SER THR VAL MET 0.467066 0.84
40 LEU PRO PHE ASP LYS THR THR ILE MET 0.461078 0.826667
41 ILE SER PRO ARG THR LEU ASP ALA TRP 0.459016 0.848101
42 PRO ARG ARG PRO VAL ILE MET ARG ARG 0.455696 0.837838
43 ASN LEU VAL PRO MET VAL ALA THR VAL 0.455128 0.8
44 PRO PRO ARG PRO ILE TYR ASN ARG ASN 0.454545 0.868421
45 PHE TYR ARG ALA LEU MET 0.453947 0.746667
46 PTR VAL PRO MET LEU 0.453947 0.772152
47 GLY TYR GLN ASP TYR GLU PRO GLU ALA 0.452703 0.72973
48 ASN ARG PRO ILE LEU SER LEU 0.45098 0.805195
49 LYS LEU TYR GLN ASN PRO THR THR TYR ILE 0.447059 0.782051
50 ARG PRO ARG PRO ASP ASP LEU GLU ILE 0.446541 0.813333
51 LEU SER SER PRO VAL THR LYS SER PHE 0.446541 0.797297
52 GLU LEU LYS ARG LYS MET ILE TYR MET 0.446541 0.773333
53 ARG LEU TYR HIS SEP LEU PRO ALA 0.445087 0.807229
54 GLN ASN GLY PTR VAL ASN PRO THR TYR 0.444444 0.73494
55 ASP LEU THR ARG PRO 0.444444 0.851351
56 HIS SER ILE THR TYR LEU LEU PRO VAL 0.444444 0.807692
57 LEU LEU PHE GLY LYS PRO VAL TYR VAL 0.443787 0.74026
58 TYR SEP PRO THR SEP PRO SER 0.442953 0.75
59 GLU ARG THR ILE PRO ILE THR ARG GLU 0.441558 0.84
60 ASN TYR THR PRO GLY PRO GLY ILE ARG PHE 0.441341 0.858974
61 ASN PHE ASP ASN PRO VAL TYR ARG LYS THR 0.441341 0.883117
62 MET TYR TRP TYR PRO TYR 0.440252 0.766234
63 LEU LEU PHE GLY TYR PRO VAL TYR VAL 0.439759 0.75
64 LEU LEU PHE GLY PHE PRO VAL TYR VAL 0.439759 0.75
65 SER ARG ASP HIS SER ARG THR PRO MET 0.439306 0.896104
66 ARG PRO LYS PRO LEU VAL ASP PRO 0.438356 0.794521
67 ALA PRO GLN PRO ALA PRO GLU ASN ALA TYR 0.438272 0.776316
68 TYR LEU LYS GLU PRO VAL HIS GLY VAL 0.436782 0.766234
69 LYS PRO ILE VAL VAL LEU HIS GLY TYR 0.436782 0.75641
70 ILE GLY PRO GLY ARG ALA PHE TYR THR ILE 0.435754 0.857143
71 ASP TYR GLU PRO ILE PRO GLU GLU ALA PHE 0.435294 0.753247
72 DPN PRO DAR ILE NH2 0.434483 0.756757
73 LEU PRO PHE ASP LYS SER THR ILE MET 0.434286 0.828947
74 DHI PRO PHE HIS LEU LEU VAL TYR 0.431818 0.753247
75 LYS ALA PRO ARG ALY GLN LEU ALA THR LYS 0.431138 0.853333
76 LEU PRO PRO LEU ASP ILE THR PRO TYR 0.431138 0.8
77 ARG ARG LEU PRO ILE PHE SER ARG LEU 0.431138 0.866667
78 TYR PRO TYR 0.430769 0.68
79 GLY GLU ARG THR ILE PRO ILE THR ARG GLU 0.43038 0.84
80 SER HIS PRO ARG PRO ILE ARG VAL 0.430303 0.844156
81 ALA ARG THR MLY GLN THR ALA ARG TYR 0.429487 0.853333
82 PHE ALA PRO GLY PHE PHE PRO TYR LEU 0.429448 0.766234
83 LYS THR PHE PRO PRO THR GLU PRO LYS 0.427711 0.77027
84 CYS THR PRO SER ARG 0.424658 0.824324
85 ALA ASN SER ARG PHE PRO THR SER ILE ILE 0.424419 0.831169
86 ILE SER TYR GLY ASN ASP ALA LEU MET PRO 0.423729 0.857143
87 DPN PRO ARG 0.423358 0.739726
88 LEU PHE GLY TYR PRO VAL TYR VAL 0.423313 0.75
89 GLU LEU ASN ARG LYS MET ILE TYR MET 0.422619 0.789474
90 LYS LEU THR PRO LEU CYS VAL THR LEU 0.422078 0.794521
91 MET TRP ARG PRO TRP 0.420732 0.792208
92 ALA ARG SER HIS SEP TYR PRO ALA 0.420455 0.795181
93 LEU TYR ALA SER PRO GLN LEU GLU GLY PHE 0.418079 0.779221
94 SER GLU LEU GLU ILE LYS ARG TYR 0.417722 0.75
95 MET SER LEU PRO GLY ARG TRP LYS PRO LYS 0.417112 0.897436
96 ASN LEU VAL PRO MET VAL ALA VAL VAL 0.416667 0.733333
97 ASN LEU VAL PRO MET VAL ALA ALA VAL 0.416667 0.733333
98 LYS GLY PRO PRO LEU PRO ARG PRO ARG VAL 0.416107 0.794521
99 VAL VAL ARG PRO GLY SER LEU ASP LEU PRO 0.415205 0.853333
100 ASN GLY TYR GLU ASN PRO THR TYR LYS 0.415205 0.779221
101 GLN ASN TYR PRO ILE VAL GLN 0.415094 0.776316
102 TYR PRO SER LYS PRO ASP ASN PRO GLY GLU 0.414474 0.773333
103 ALA THR VAL ARG THR TYR SER CYS 0.414474 0.756757
104 GLU LEU LYS TPO GLU ARG TYR 0.4125 0.725
105 PHE PRO THR LYS ASP VAL ALA LEU 0.412121 0.783784
106 LEU GLU LYS ALA ARG GLY SER THR TYR 0.411765 0.786667
107 PHE ALA PRO GLY ASN TYR PRO ALA LEU 0.411765 0.794872
108 ARG ILE ILE PRO ARG HIS LEU GLN LEU 0.411429 0.792208
109 ALA PRO THR MET PRO PRO PRO LEU PRO PRO 0.410596 0.824324
110 ALA LEU PRO HIS ALA ILE LEU ARG LEU 0.409357 0.789474
111 ARG PRO GLY ASN PHE LEU GLN SER ARG PRO 0.40884 0.844156
112 GLY LEU LEU GLY SER PRO VAL ARG ALA 0.408805 0.8
113 VAL TYR PRO IAS HIS ALA 0.408537 0.74026
114 GLY PHE ARG PRO 0.408451 0.743243
115 LYS LEU PRO ALA GLN PHE TYR ILE LEU 0.408046 0.753247
116 ALA ASN SER ARG TRP PRO THR SER ALY ILE 0.407821 0.848101
117 ARG GLN ALA SEP ILE GLU LEU PRO SER MET 0.406417 0.817073
118 PHE ASN PHE PRO GLN ILE THR 0.40625 0.730769
119 VAL ORN LEU DPN PRO VAL ORN LEU DPN PRO 0.40625 0.693333
120 LYS GLN GLU PRO GLN GLU ILE ASP PHE 0.405882 0.706667
121 PRO THR SEP PRO SER TYR 0.404908 0.7375
122 DPN PRO DAR CYS NH2 0.40411 0.739726
123 GLU VAL ALA PRO PRO GLU TYR HIS ARG LYS 0.403141 0.833333
124 THR PRO ARG ARG SER MLZ SER ALA 0.402597 0.866667
125 ARG ARG ARG GLU ARG SER PRO THR ARG 0.402516 0.813333
126 SER TYR SEP PRO THR SEP PRO SEP TYR SER 0.402516 0.725
127 LEU PRO GLU THR GLY 0.401408 0.743243
128 SER PRO THR SER PRO SEP TYR SER PRO PRO 0.401198 0.7375
129 ILE LEU GLY PRO PRO GLY SER VAL TYR 0.401163 0.815789
130 ILE LEU LYS GLU PRO VAL HIS GLY VAL 0.4 0.701299
131 GLY TYR GLU ASN PRO THR TYR LYS PHE PHE 0.4 0.766234
132 ALA ASN SER ARG VAL PRO THR SER ILE ILE 0.4 0.84
Similar Binding Sites
Pocket no: 1; Query (leader) PDB : 4O2C; Ligand: ACE; Similar sites found: 307
This union binding pocket (no: 1) in the query (biounit: 4o2c.bio1) has 51 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc)
1 4O2C ACE 3.39e-23 1
2 3BHB LYS 9.992e-16 0.73035
3 1LEK GLU 5.612e-16 0.71012
4 1INQ SER 1.11e-15 0.70122
5 4QRS GLU 3.067e-16 0.69919
6 4QRT GLU 4.735e-16 0.6781
7 1JUF SER 6.55e-15 0.66892
8 3RWG MET 4.974e-14 0.64838
9 3KYO LYS 3.109e-15 0.63884
10 2X4T ASN 2.531e-14 0.63578
11 4G9F LYS 1.232e-11 0.6236
12 1MI5 PHE 2.336e-13 0.62264
13 3BZF VAL 1.419e-13 0.61853
14 4QRQ HIS 8.105e-15 0.60773
15 1S7U LYS 9.848e-14 0.60002
16 1LP9 ALA 7.544e-12 0.59109
17 1S7X LYS 1.27e-13 0.58914
18 1TMC GLU 8.425e-13 0.57599
19 3VXS ARG 4.934e-10 0.57294
20 4WJ5 GRN 1.877e-13 0.57253
21 1K8D ILE 1.416e-13 0.57145
22 4G43 ILE 4.543e-13 0.56985
23 1S7Q ALA 1.902e-13 0.56885
24 1MWA GLU 5.78e-11 0.56739
25 4L8D ALA 2.912e-13 0.56537
26 3FON VAL 1.784e-13 0.56117
27 1OGA GLY 4.061e-11 0.5609
28 4JFF GLU 3.16e-11 0.56019
29 3QFJ LEU 1.592e-10 0.55576
30 1BII ARG 9.428e-13 0.55487
31 2BNQ SER 6.388e-10 0.55194
32 3VJ6 ALA 4.554e-13 0.55104
33 3GJF SER 2.325e-10 0.55045
34 2DYP ARG 7.128e-13 0.54954
35 3QQ4 ALA 6.097e-13 0.54891
36 1FO0 ILE 1.186e-11 0.54837
37 3VXM ARG 1.134e-09 0.54431
38 1ZT1 PHE 1.9e-12 0.54354
39 1BD2 LEU 1.86e-10 0.54349
40 3VH8 LEU 1.145e-13 0.54335
41 1KJM ALA 5.39e-13 0.54092
42 1W72 GLU 6.229e-10 0.54019
43 1KJV ASN 5.994e-12 0.53975
44 3PWU ILE 1.191e-12 0.53659
45 3ECB ARG 4.617e-12 0.53459
46 2OI9 GLN 2.054e-09 0.53173
47 3TJH SER 1.519e-09 0.52907
48 1S7W LYS 4.535e-12 0.5287
49 3QDJ ALA 4.265e-10 0.51953
50 1QO3 ARG 4.541e-12 0.51814
51 1MHC FME 2.085e-09 0.46756
52 3ERY GLN 2.29e-09 0.46332
53 2H26 6UL 3.677e-05 0.43133
54 3G08 FEE 7.156e-05 0.42109
55 3D2U ALA 1.516e-08 0.41895
56 1GNI OLA 0.01713 0.40742
57 2P4Y C03 0.0003106 0.39767
58 1D5Z ACE 0.0001782 0.38921
59 3B1M KRC 0.0005925 0.37613
60 3QUZ QUV 0.001082 0.37375
61 3L9R L9R 0.0001473 0.37316
62 3L9R L9Q 0.0002011 0.37248
63 3HUJ AGH 0.0006862 0.3722
64 2Z7I 742 0.003236 0.35782
65 4L4V 1VY 2.908e-06 0.35765
66 3KDU NKS 0.003217 0.35496
67 1ONQ SLF 0.000429 0.34725
68 3SCM LGN 0.01927 0.33892
69 4WO4 JLS 0.005963 0.33689
70 1FM4 DXC 0.02817 0.33647
71 3E85 BSU 0.02121 0.33629
72 2Q1H AS4 0.02034 0.33503
73 3GZ9 D32 0.02967 0.33491
74 1PME SB2 0.03239 0.33342
75 2QE4 JJ3 0.01969 0.33101
76 3T4V MD3 0.02133 0.32971
77 2QHD DAO 0.04571 0.329
78 4IAE 1DX 0.01125 0.32695
79 4N84 GLY 0.02124 0.32549
80 1ZB6 GST 0.004289 0.32528
81 3BEF ASP 0.004194 0.32494
82 2I0G I0G 0.03739 0.324
83 3O9L LPN 0.02177 0.32342
84 3G9E RO7 0.00944 0.32302
85 2HFP NSI 0.03069 0.32173
86 3KFC 61X 0.02704 0.32068
87 4KCF FMN 0.04603 0.32007
88 2F7A CCU 0.01144 0.32005
89 3LMP CEK 0.02821 0.31999
90 3BEF ASN 0.006694 0.3195
91 2A1L PCW 0.02846 0.31938
92 3LVW GSH 0.04777 0.31934
93 4ANW O92 0.01949 0.31801
94 3OV6 MK0 0.01079 0.31711
95 3SXF BK5 0.03752 0.31661
96 3WDX BGC 0.01249 0.31589
97 4PJT 2YQ 0.02824 0.31532
98 4F7E 0SH 0.00255 0.31517
99 3IU9 T07 0.04939 0.31368
100 3V2Q PLM 0.04751 0.31265
101 3LDW ZOL 0.008917 0.31203
102 2WLG SOP 0.02016 0.31182
103 1KGI T4A 0.01413 0.31157
104 4RC8 STE 0.002674 0.31112
105 3ND6 ATP 0.03116 0.31108
106 1FBY REA 0.02183 0.31035
107 3MNP DEX 0.0384 0.31017
108 3SUD SUE 0.04763 0.3095
109 4OAS 2SW 0.0343 0.3092
110 2YAK OSV 0.02337 0.30892
111 3LXK MI1 0.04955 0.30842
112 4RC7 PL3 0.001319 0.30708
113 2X4Z X4Z 0.04549 0.30646
114 4IEH 1E9 0.007079 0.30641
115 1SR7 MOF 0.04828 0.30621
116 4H2V AMP 0.01555 0.306
117 2BCG GER 0.0001893 0.30578
118 3MF2 AMP 0.01456 0.30568
119 1DKF BMS 0.004788 0.30534
120 4OAR 2S0 0.002488 0.30494
121 2HFN FMN 0.01299 0.3049
122 1OSH FEX 0.04328 0.30469
123 4LBK GAL 0.002315 0.30406
124 4CSJ NN7 0.009276 0.30376
125 3QKD HI0 0.03556 0.30299
126 2A3I C0R 0.003765 0.30291
127 3AGC RCC 0.0263 0.3028
128 3T58 FAD 0.03848 0.30195
129 4IE6 UN9 0.0372 0.30181
130 2B1Z 17M 0.04239 0.30179
131 3JUQ AKD 0.0189 0.29987
132 4I6G FAD 0.03452 0.2998
133 4O4Z N2O 0.01467 0.29973
134 1GQG DCD 0.01823 0.2993
135 2NPA MMB 0.002127 0.29922
136 1X0P FAD 0.01825 0.29901
137 1GT4 UNA 0.007289 0.29874
138 3QCJ NX4 0.01494 0.29829
139 4OHA HFT 0.01926 0.29827
140 2GQS C2R 0.005173 0.29817
141 3KMZ EQO 0.01157 0.29809
142 4MK0 29X 0.02958 0.29805
143 2O5L MNR 0.009043 0.29787
144 4IPH 1FJ 0.04891 0.29784
145 4HW3 19G 0.01031 0.29738
146 4TW7 37K 0.03308 0.29716
147 2J3M ATP 0.02114 0.29699
148 1K7L 544 0.02262 0.29675
149 2C43 COA 0.01851 0.29598
150 3RYC GDP 0.02454 0.29572
151 3RGA LSB 0.00793 0.29557
152 2QV6 GTP 0.03991 0.2955
153 3CB2 GDP 0.02072 0.29513
154 2ZHL NAG 0.03933 0.29436
155 3HR1 PF9 0.0278 0.2943
156 4BG4 ADP 0.01207 0.29411
157 4DXD 9PC 0.02033 0.29366
158 1U3R 338 0.01589 0.29365
159 3GFZ FMN 0.02931 0.29332
160 3ZLR X0B 0.04398 0.29331
161 1KZN CBN 0.02376 0.29285
162 2ZPA ADP 0.02366 0.29249
163 1NHZ 486 0.03552 0.29219
164 1DZK PRZ 0.02379 0.29201
165 3B6R ADP 0.01294 0.29198
166 4HA9 NDP 0.01891 0.29191
167 3AXY ARG 0.04298 0.2919
168 4MQ1 2C3 0.03407 0.29178
169 3JRX S1A 0.01622 0.2913
170 4MYD 164 0.01862 0.29099
171 2BJ4 OHT 0.01146 0.29095
172 4E4N 0NL 0.02017 0.29094
173 3DCT 064 0.03888 0.29042
174 3ACL 3F1 0.008095 0.28977
175 4I5C C5I 0.03034 0.28926
176 4OXX FMN 0.0304 0.28918
177 1AWI PRO 0.0475 0.28827
178 4IBF 1D5 0.01885 0.28799
179 4EMV 0R9 0.03708 0.28751
180 2AGC DAO 0.03851 0.28737
181 4NY3 PRO 6.422e-05 0.28693
182 2CJ9 SSA 0.04641 0.28675
183 4JE7 BB2 0.02414 0.2864
184 2AZ5 307 0.02041 0.28583
185 2P54 735 0.03108 0.28559
186 2P1C GG3 0.04082 0.28517
187 2IL4 COA 0.02351 0.28515
188 1XKV ATP 0.009856 0.28453
189 3CV0 ASN 0.02741 0.28383
190 4PAB THG 0.02432 0.28371
191 1YRE COA 0.04158 0.28365
192 1K2V DEF 0.04433 0.28339
193 2Q7J TES 0.02351 0.283
194 3FJO FMN 0.04631 0.28294
195 1F20 NAP 0.02426 0.2828
196 4DK7 0KS 0.02677 0.28279
197 3G5K BB2 0.02576 0.282
198 2YJD YJD 0.03998 0.28194
199 1RV0 DAN 0.04207 0.28157
200 4FE2 AIR 0.01351 0.28054
201 2QZO KN1 0.04353 0.28054
202 4HN1 TYD 0.02369 0.28041
203 3SAO NKN 0.02201 0.28018
204 1PCX LEU 0.01774 0.27995
205 1W96 S1A 0.03396 0.27981
206 3SAO DBH 0.02792 0.27941
207 3B5J 12D 0.006822 0.27923
208 4UWH JXM 0.03253 0.27862
209 3SP6 IL2 0.01179 0.27832
210 2WOR 2AN 0.04855 0.27821
211 4FH7 TBP 0.03151 0.27748
212 1YC4 43P 0.02664 0.2773
213 4IAW LIZ 0.02532 0.27633
214 3ET1 ET1 0.01769 0.27569
215 3TL1 JRO 0.007625 0.27559
216 2J9L ATP 0.02167 0.27547
217 4I67 G 0.02372 0.27494
218 1FM9 9CR 0.04265 0.27484
219 2WA8 PHE 0.03303 0.27449
220 1M2Z BOG 0.008158 0.27447
221 4DSU BZI 0.006005 0.27444
222 2WA8 PHE 0.03373 0.2744
223 2UW1 GVM 0.003252 0.27438
224 4MGB XDH 0.04487 0.27386
225 3RLF MAL 0.003349 0.27373
226 4BTB PRO 0.001864 0.27346
227 1XN0 ROL 0.01533 0.27261
228 1T7F DHT 0.03445 0.2722
229 1T7M DHT 0.03268 0.27168
230 4JMU 1ML 0.0268 0.27159
231 1UMZ BGC 0.03555 0.27107
232 1VDN ACE 0.03693 0.27085
233 4I53 1C1 0.03865 0.27069
234 4W9N TCL 0.004207 0.27068
235 1DZT TPE 0.007318 0.27064
236 2HRL SIA 0.003234 0.27031
237 2QHS OCA 0.03396 0.27025
238 2OBM ADP 0.004281 0.26958
239 4J6W CTP 0.01348 0.26946
240 1MQB ANP 0.05 0.26937
241 4DOL PLM 0.03917 0.26937
242 3ZHF ASN 0.03277 0.26911
243 2IYF UDP 0.02627 0.26907
244 2YKL NLD 0.009467 0.26823
245 3GD9 GLC 0.04835 0.26812
246 3D9T ALA 0.04002 0.26801
247 1RZX ACE 0.01284 0.26758
248 2DPY ADP 0.0005421 0.26746
249 3OYW TDG 0.01997 0.26638
250 3NHB ADP 0.02383 0.26593
251 3JU6 ANP 0.04772 0.26511
252 1Z03 OCH 0.03447 0.26489
253 3DBX PLM 0.02441 0.26413
254 4CGU SER 0.0417 0.264
255 1WZ1 DNS 0.0398 0.26343
256 4BMB LAT 0.01201 0.26343
257 4MGD 27N 0.0256 0.26235
258 2WZ5 MET 8.805e-05 0.26227
259 3CM2 X23 0.03504 0.26204
260 4CQK PIO 0.02469 0.26159
261 4I54 1C1 0.02777 0.26155
262 3I6B KDO 0.04067 0.26154
263 1TV5 N8E 0.0002157 0.26146
264 2W3L DRO 0.03746 0.26143
265 2AWN ADP 0.0208 0.26087
266 1I31 PHE 0.02741 0.26077
267 1LOP SIN 0.03325 0.2607
268 3HYW DCQ 0.0277 0.26053
269 3SQP 3J8 0.02526 0.26045
270 1EXF GLY 0.01079 0.26005
271 2XG5 EC5 0.04148 0.25988
272 2D2F ADP 0.023 0.2595
273 4NFD SIA 0.03023 0.25938
274 2XG5 EC2 0.02125 0.25902
275 3CBC DBS 0.004473 0.25897
276 2G30 ALA 0.000335 0.25855
277 3ZJX BOG 0.02172 0.25796
278 4K55 H6P 0.002542 0.25751
279 2PSJ CEI 0.03849 0.25723
280 2HO2 PRO 0.01541 0.25719
281 1OFL NGK 0.01703 0.2559
282 3QRC SCR 7.106e-05 0.25575
283 2YMZ LAT 0.02169 0.25517
284 1ZOY UQ1 0.03842 0.2545
285 4IKN ASP 0.03904 0.25383
286 1OIJ AKG 0.03239 0.25319
287 4G0A G 0.04558 0.25251
288 3TDC 0EU 8.755e-05 0.25243
289 3R9V DXC 0.01312 0.25234
290 3W5J GDP 0.04381 0.25192
291 2VWA PTY 0.01899 0.25189
292 2BHW NEX 0.00414 0.25125
293 1XPJ TLA 0.01506 0.24818
294 4MRP GSH 0.03815 0.24818
295 3AQZ BGC 0.004025 0.24764
296 3ETG GWD 0.02296 0.2468
297 1KTG AMP 0.03087 0.24596
298 3SXU ASP 0.002162 0.24529
299 1JXM 5GP 0.004217 0.2439
300 4CT7 TRP 0.02579 0.24355
301 2XOM GAL 0.0261 0.24328
302 3O01 DXC 0.003799 0.24279
303 3F5A SIA 0.02383 0.24262
304 4G9Z C 0.01351 0.2425
305 4C01 QY9 0.04696 0.24014
306 2CIX CEJ 0.026 0.23897
307 1HBK MYR 0.02293 0.23661
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