Receptor
PDB id Resolution Class Description Source Keywords
1A28 1.8 Å NON-ENZYME: SIGNAL_HORMONE HORMONE-BOUND HUMAN PROGESTERONE RECEPTOR LIGAND-BINDING DOMAIN HOMO SAPIENS PROGESTERONE RECEPTOR STEROID RECEPTOR NUCLEAR RECEPTOR TRANSCRIPTION REGULATION
Ref.: AROMATIC BETA-AMINO-KETONE DERIVATIVES AS NOVEL SELECTIVE NON-STEROIDAL PROGESTERONE RECEPTOR AGONISTS. BIOORG MED CHEM V. 18 4255 2010
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
STR A:1;
B:2;
Valid;
Valid;
none;
none;
Ki = 5.1 nM
314.462 C21 H30 O2 CC(=O...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1SR7 1.46 Å NON-ENZYME: SIGNAL_HORMONE PROGESTERONE RECEPTOR HORMONE BINDING DOMAIN WITH BOUND MOME FUROATE HOMO SAPIENS PROGESTERONE RECEPTOR MOMETASONE PROGESTERONE NUCLEAR RECHORMONE RECEPTOR TRANSCRIPTION
Ref.: PROGESTERONE RECEPTOR LIGAND BINDING POCKET FLEXIBI CRYSTAL STRUCTURES OF THE NORETHINDRONE AND MOMETAS FUROATE COMPLEXES J.MED.CHEM. V. 47 3381 2004
Members (14)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 224 families.
1 3ZRA - ORB C18 H17 Cl F N3 O3 S Cc1c(c(on1....
2 1SQN Kd = 0.4 nM NDR C20 H26 O2 CC12CCC3C(....
3 3G8O ic50 = 125 nM 30X C15 H15 F6 N3 O CC(C(=O)N(....
4 3ZRB - OR8 C17 H19 Cl N4 O3 S Cc1c(c(on1....
5 3KBA ic50 = 16 nM WOW C20 H22 Cl N3 O2 S Cc1ccccc1C....
6 4A2J - AS0 C28 H35 N O4 CC12CC(C3=....
7 2W8Y - NDR C20 H26 O2 CC12CCC3C(....
8 4APU - OR8 C17 H19 Cl N4 O3 S Cc1c(c(on1....
9 3HQ5 ic50 = 16 nM GKK C20 H19 Cl F3 N3 CN1CCC(C1)....
10 1A28 Ki = 5.1 nM STR C21 H30 O2 CC(=O)C1CC....
11 1ZUC ic50 = 1.7 nM T98 C16 H15 N3 O S CC1(c2cc(c....
12 3ZR7 - OR8 C17 H19 Cl N4 O3 S Cc1c(c(on1....
13 1SR7 Kd = 0.08 nM MOF C27 H30 Cl2 O6 CC1CC2C3CC....
14 3D90 - NOG C21 H28 O2 CCC12CCC3C....
70% Homology Family (76)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 172 families.
1 3RY9 - 1CA C21 H30 O3 CC12CCC3C(....
2 1I38 - DHT C19 H30 O2 CC12CCC(=O....
3 1XNN Ki = 0.5 nM HYQ C20 H18 N2 O4 c1ccc2c(c1....
4 2PIP - ICO C9 H7 N O2 c1ccc2c(c1....
5 2AMA - DHT C19 H30 O2 CC12CCC(=O....
6 1E3G - R18 C19 H24 O2 CC1(CCC2C1....
7 2AX9 Ki = 0.3 nM BHM C11 H10 Br F3 N2 O4 CC(CBr)(C(....
8 2AMB - 17H C21 H28 O2 CCC1(CCC2C....
9 4OEA - DHT C19 H30 O2 CC12CCC(=O....
10 3B67 - B67 C17 H10 F8 N2 O5 CC(COc1c(c....
11 3RLL - RLL C23 H16 F3 N3 O3 CC(COc1ccc....
12 2PIU - DHT C19 H30 O2 CC12CCC(=O....
13 2AXA Ki = 6.1 nM FHM C17 H14 F4 N2 O5 CC(COc1ccc....
14 2YLO - TES C19 H28 O2 CC12CCC3C(....
15 2PNU - ENM C27 H36 F2 O3 CC12CCC(=O....
16 4HLW - 17W C15 H14 N2 O S c1ccc(cc1)....
17 2PIQ - RB1 C16 H19 N5 O CC(C)(C)n1....
18 2HVC - LGD C14 H9 F9 N2 O c1cc2c(cc1....
19 2OZ7 - CA4 C24 H29 Cl O4 CC(=O)C1(C....
20 3B65 - 3B6 C18 H14 I N3 O3 CC(COc1ccc....
21 2IHQ Ki = 3.2 nM LG7 C17 H13 N3 O3 c1ccc2c(c1....
22 3B68 - B68 C19 H18 F3 N3 O6 CC(=O)Nc1c....
23 3B5R - B5R C18 H13 Cl F4 N2 O3 CC(COc1ccc....
24 2AX8 - FHM C17 H14 F4 N2 O5 CC(COc1ccc....
25 2PIV - T3 C15 H12 I3 N O4 c1cc(c(cc1....
26 2PIX - FLF C14 H10 F3 N O2 c1ccc(c(c1....
27 2QPY - DHT C19 H30 O2 CC12CCC(=O....
28 2PIR - NK C7 H6 O2 c1ccc(c(c1....
29 2YHD Ki = 23 uM AV6 C17 H14 N2 O2 c1cc2cccc3....
30 1T7T - DHT C19 H30 O2 CC12CCC(=O....
31 1Z95 Kd = 0.76 nM 198 C18 H14 F4 N2 O4 S CC(CS(=O)(....
32 3RLJ - RLJ C19 H14 F3 N3 O3 CC(COc1ccc....
33 2AX6 - HFT C11 H11 F3 N2 O4 CC(C)(C(=O....
34 2PKL - DHT C19 H30 O2 CC12CCC(=O....
35 2AX7 - FHM C17 H14 F4 N2 O5 CC(COc1ccc....
36 2PIO - DHT C19 H30 O2 CC12CCC(=O....
37 3ZQT - TES C19 H28 O2 CC12CCC3C(....
38 1GS4 - ZK5 C21 H29 F O5 CC12CCC(=O....
39 2AM9 - TES C19 H28 O2 CC12CCC3C(....
40 3B66 - B66 C18 H16 F3 N3 O5 CC(COc1ccc....
41 1XQ3 - R18 C19 H24 O2 CC1(CCC2C1....
42 2PIT - DHT C19 H30 O2 CC12CCC(=O....
43 3G0W Ki = 0.3 nM LGB C15 H13 Cl F3 N3 O2 Cc1c(ccc(c....
44 4OJB - 198 C18 H14 F4 N2 O4 S CC(CS(=O)(....
45 2YLQ - TES C19 H28 O2 CC12CCC3C(....
46 1I37 - DHT C19 H30 O2 CC12CCC(=O....
47 2YLP - TES C19 H28 O2 CC12CCC3C(....
48 3ZRA - ORB C18 H17 Cl F N3 O3 S Cc1c(c(on1....
49 1SQN Kd = 0.4 nM NDR C20 H26 O2 CC12CCC3C(....
50 3G8O ic50 = 125 nM 30X C15 H15 F6 N3 O CC(C(=O)N(....
51 3ZRB - OR8 C17 H19 Cl N4 O3 S Cc1c(c(on1....
52 3KBA ic50 = 16 nM WOW C20 H22 Cl N3 O2 S Cc1ccccc1C....
53 4A2J - AS0 C28 H35 N O4 CC12CC(C3=....
54 2W8Y - NDR C20 H26 O2 CC12CCC3C(....
55 4APU - OR8 C17 H19 Cl N4 O3 S Cc1c(c(on1....
56 3HQ5 ic50 = 16 nM GKK C20 H19 Cl F3 N3 CN1CCC(C1)....
57 1A28 Ki = 5.1 nM STR C21 H30 O2 CC(=O)C1CC....
58 1ZUC ic50 = 1.7 nM T98 C16 H15 N3 O S CC1(c2cc(c....
59 3ZR7 - OR8 C17 H19 Cl N4 O3 S Cc1c(c(on1....
60 1SR7 Kd = 0.08 nM MOF C27 H30 Cl2 O6 CC1CC2C3CC....
61 3D90 - NOG C21 H28 O2 CCC12CCC3C....
62 3VHV ic50 = 510 nM LD1 C18 H13 N5 O2 S c1ccc(cc1)....
63 2AB2 - SNL C24 H32 O4 S CC(=O)SC1C....
64 2AA2 - AS4 C21 H28 O5 CC12CCC(=O....
65 1YA3 - STR C21 H30 O2 CC(=O)C1CC....
66 2AAX - PDN C21 H26 O5 CC12CC(=O)....
67 2AA7 - 1CA C21 H30 O3 CC12CCC3C(....
68 2OAX - SNL C24 H32 O4 S CC(=O)SC1C....
69 1Y9R - 1CA C21 H30 O3 CC12CCC3C(....
70 4PF3 ic50 = 71 nM HFN C21 H18 F3 N3 O3 Cc1c(c(n(n....
71 2AA6 - STR C21 H30 O2 CC(=O)C1CC....
72 2Q3Y - PRO ALA ILE LEU TYR ALA LEU LEU SER SER n/a n/a
73 4LTW - STR C21 H30 O2 CC(=O)C1CC....
74 2Q1H - AS4 C21 H28 O5 CC12CCC(=O....
75 2Q1V - PDN C21 H26 O5 CC12CC(=O)....
76 1NHZ - 486 C29 H35 N O2 CC#CC1(CCC....
50% Homology Family (78)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 145 families.
1 3RY9 - 1CA C21 H30 O3 CC12CCC3C(....
2 1I38 - DHT C19 H30 O2 CC12CCC(=O....
3 1XNN Ki = 0.5 nM HYQ C20 H18 N2 O4 c1ccc2c(c1....
4 2PIP - ICO C9 H7 N O2 c1ccc2c(c1....
5 2AMA - DHT C19 H30 O2 CC12CCC(=O....
6 1E3G - R18 C19 H24 O2 CC1(CCC2C1....
7 2AX9 Ki = 0.3 nM BHM C11 H10 Br F3 N2 O4 CC(CBr)(C(....
8 2AMB - 17H C21 H28 O2 CCC1(CCC2C....
9 4OEA - DHT C19 H30 O2 CC12CCC(=O....
10 3B67 - B67 C17 H10 F8 N2 O5 CC(COc1c(c....
11 3RLL - RLL C23 H16 F3 N3 O3 CC(COc1ccc....
12 2PIU - DHT C19 H30 O2 CC12CCC(=O....
13 2AXA Ki = 6.1 nM FHM C17 H14 F4 N2 O5 CC(COc1ccc....
14 2YLO - TES C19 H28 O2 CC12CCC3C(....
15 2PNU - ENM C27 H36 F2 O3 CC12CCC(=O....
16 4HLW - 17W C15 H14 N2 O S c1ccc(cc1)....
17 2PIQ - RB1 C16 H19 N5 O CC(C)(C)n1....
18 2HVC - LGD C14 H9 F9 N2 O c1cc2c(cc1....
19 2OZ7 - CA4 C24 H29 Cl O4 CC(=O)C1(C....
20 3B65 - 3B6 C18 H14 I N3 O3 CC(COc1ccc....
21 2IHQ Ki = 3.2 nM LG7 C17 H13 N3 O3 c1ccc2c(c1....
22 3B68 - B68 C19 H18 F3 N3 O6 CC(=O)Nc1c....
23 3B5R - B5R C18 H13 Cl F4 N2 O3 CC(COc1ccc....
24 2AX8 - FHM C17 H14 F4 N2 O5 CC(COc1ccc....
25 2PIV - T3 C15 H12 I3 N O4 c1cc(c(cc1....
26 2PIX - FLF C14 H10 F3 N O2 c1ccc(c(c1....
27 2QPY - DHT C19 H30 O2 CC12CCC(=O....
28 2PIR - NK C7 H6 O2 c1ccc(c(c1....
29 2YHD Ki = 23 uM AV6 C17 H14 N2 O2 c1cc2cccc3....
30 1T7T - DHT C19 H30 O2 CC12CCC(=O....
31 1Z95 Kd = 0.76 nM 198 C18 H14 F4 N2 O4 S CC(CS(=O)(....
32 3RLJ - RLJ C19 H14 F3 N3 O3 CC(COc1ccc....
33 2AX6 - HFT C11 H11 F3 N2 O4 CC(C)(C(=O....
34 2PKL - DHT C19 H30 O2 CC12CCC(=O....
35 2AX7 - FHM C17 H14 F4 N2 O5 CC(COc1ccc....
36 2PIO - DHT C19 H30 O2 CC12CCC(=O....
37 3ZQT - TES C19 H28 O2 CC12CCC3C(....
38 1GS4 - ZK5 C21 H29 F O5 CC12CCC(=O....
39 2AM9 - TES C19 H28 O2 CC12CCC3C(....
40 3B66 - B66 C18 H16 F3 N3 O5 CC(COc1ccc....
41 1XQ3 - R18 C19 H24 O2 CC1(CCC2C1....
42 2PIT - DHT C19 H30 O2 CC12CCC(=O....
43 3G0W Ki = 0.3 nM LGB C15 H13 Cl F3 N3 O2 Cc1c(ccc(c....
44 4OJB - 198 C18 H14 F4 N2 O4 S CC(CS(=O)(....
45 2YLQ - TES C19 H28 O2 CC12CCC3C(....
46 1I37 - DHT C19 H30 O2 CC12CCC(=O....
47 2YLP - TES C19 H28 O2 CC12CCC3C(....
48 3ZRA - ORB C18 H17 Cl F N3 O3 S Cc1c(c(on1....
49 1SQN Kd = 0.4 nM NDR C20 H26 O2 CC12CCC3C(....
50 3G8O ic50 = 125 nM 30X C15 H15 F6 N3 O CC(C(=O)N(....
51 3ZRB - OR8 C17 H19 Cl N4 O3 S Cc1c(c(on1....
52 3KBA ic50 = 16 nM WOW C20 H22 Cl N3 O2 S Cc1ccccc1C....
53 4A2J - AS0 C28 H35 N O4 CC12CC(C3=....
54 2W8Y - NDR C20 H26 O2 CC12CCC3C(....
55 4APU - OR8 C17 H19 Cl N4 O3 S Cc1c(c(on1....
56 3HQ5 ic50 = 16 nM GKK C20 H19 Cl F3 N3 CN1CCC(C1)....
57 1A28 Ki = 5.1 nM STR C21 H30 O2 CC(=O)C1CC....
58 1ZUC ic50 = 1.7 nM T98 C16 H15 N3 O S CC1(c2cc(c....
59 3ZR7 - OR8 C17 H19 Cl N4 O3 S Cc1c(c(on1....
60 1SR7 Kd = 0.08 nM MOF C27 H30 Cl2 O6 CC1CC2C3CC....
61 3D90 - NOG C21 H28 O2 CCC12CCC3C....
62 3VHU ic50 = 49 nM SNL C24 H32 O4 S CC(=O)SC1C....
63 2AA5 - STR C21 H30 O2 CC(=O)C1CC....
64 3VHV ic50 = 510 nM LD1 C18 H13 N5 O2 S c1ccc(cc1)....
65 2AB2 - SNL C24 H32 O4 S CC(=O)SC1C....
66 2AA2 - AS4 C21 H28 O5 CC12CCC(=O....
67 1YA3 - STR C21 H30 O2 CC(=O)C1CC....
68 2AAX - PDN C21 H26 O5 CC12CC(=O)....
69 2AA7 - 1CA C21 H30 O3 CC12CCC3C(....
70 2OAX - SNL C24 H32 O4 S CC(=O)SC1C....
71 1Y9R - 1CA C21 H30 O3 CC12CCC3C(....
72 4PF3 ic50 = 71 nM HFN C21 H18 F3 N3 O3 Cc1c(c(n(n....
73 2AA6 - STR C21 H30 O2 CC(=O)C1CC....
74 2Q3Y - PRO ALA ILE LEU TYR ALA LEU LEU SER SER n/a n/a
75 4LTW - STR C21 H30 O2 CC(=O)C1CC....
76 2Q1H - AS4 C21 H28 O5 CC12CCC(=O....
77 2Q1V - PDN C21 H26 O5 CC12CC(=O)....
78 1NHZ - 486 C29 H35 N O2 CC#CC1(CCC....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: STR; Similar ligands found: 12
No: Ligand ECFP6 Tc MDL keys Tc
1 STR 1 1
2 1CA 0.732394 0.775
3 TES 0.619718 0.833333
4 FFA 0.619718 0.833333
5 3G6 0.618421 0.861111
6 TH2 0.554217 0.775
7 K2B 0.542169 0.852941
8 DL4 0.54023 0.794872
9 ASD 0.520548 1
10 PLO 0.433735 0.857143
11 CI2 0.419753 0.870968
12 C0R 0.411111 0.738095
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1SR7; Ligand: MOF; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 1sr7.bio1) has 28 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc)
Pocket No.: 2; Query (leader) PDB : 1SR7; Ligand: MOF; Similar sites found: 375
This union binding pocket(no: 2) in the query (biounit: 1sr7.bio1) has 32 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc)
1 2A3I C0R 0.0000000000003322 0.86058
2 2BJ4 OHT 0.00000000007831 0.76717
3 3UUD EST 0.000000001015 0.75846
4 3UUA 0CZ 0.000000001263 0.75386
5 3UUA 0CZ 0.000000001263 0.75386
6 3UUD EST 0.000000001264 0.75384
7 3UUD EST 0.000000001264 0.75384
8 3UU7 2OH 0.00000003552 0.73711
9 3UUA 0CZ 0.000000008133 0.73662
10 3UU7 2OH 0.00000003695 0.72643
11 3UU7 2OH 0.00000003695 0.72643
12 2QA8 GEN 0.00000000475 0.72606
13 1YYE 196 0.00000001416 0.70314
14 2QZO KN1 0.000000008634 0.68501
15 2GIU FBR 0.0000000009282 0.67773
16 2E2R 2OH 0.00000000002814 0.66681
17 2I0G I0G 0.000000007357 0.64144
18 2B1Z 17M 0.000000006029 0.62503
19 3BQD DAY 0.00000000004858 0.61753
20 4M8E 29V 0.0000002408 0.61217
21 1FM9 9CR 0.0000002672 0.61017
22 1U3R 338 0.00000014 0.60858
23 1XIU REA 0.000000924 0.60011
24 4POJ 2VP 0.0000001695 0.5985
25 1DKF OLA 0.000003031 0.59053
26 1DKF BMS 0.0000006438 0.58025
27 3H0A 9RA 0.000002146 0.57641
28 2QE4 JJ3 0.000000001963 0.56331
29 2WOR 2AN 0.0001032 0.5567
30 1FBY REA 0.000003359 0.54407
31 2PRG BRL 0.00002024 0.53807
32 3PLZ 470 0.00002422 0.53446
33 3DCT 064 0.000006402 0.52724
34 4DK7 0KS 0.00002754 0.52615
35 1XAP TTB 0.00002156 0.52543
36 3O01 DXC 0.0002716 0.52524
37 3KMR EQN 0.00002913 0.52505
38 4DM8 REA 0.00001919 0.52234
39 3FS1 MYR 0.00006652 0.51978
40 3ET1 ET1 0.00004219 0.51776
41 3B6C SDN 0.0004057 0.51154
42 3ET1 ET1 0.00008257 0.5098
43 3PLZ 470 0.000002853 0.50704
44 1FCZ 156 0.00002614 0.50667
45 1I0B PEL 0.001241 0.50091
46 3RUU 37G 0.00001382 0.50003
47 1PZL MYR 0.0001358 0.4998
48 3TDC 0EU 0.001833 0.4982
49 1FCY 564 0.00003286 0.49797
50 1NRL SRL 0.0001088 0.49419
51 1NRL SRL 0.0001088 0.49419
52 1NRL SRL 0.0001594 0.49158
53 3IPQ 965 0.00001473 0.49078
54 1YUC EPH 0.00003066 0.49059
55 1YUC EPH 0.00003066 0.49059
56 1M13 HYF 0.00003343 0.48909
57 3CHT 4NB 0.001366 0.48383
58 1NF8 BOG 0.00222 0.48204
59 4DM8 REA 0.0001315 0.48148
60 1JGS SAL 0.001657 0.48097
61 3AQT RCO 0.001981 0.48048
62 3F33 PFL 0.002373 0.47843
63 1YUC EPH 0.0001029 0.47753
64 2HFP NSI 0.0001409 0.47597
65 4BTB PRO PRO PRO PRO PRO PRO PRO PRO PRO 0.002862 0.47243
66 3FEI CTM 0.0002734 0.47205
67 3BEJ MUF 0.000003192 0.47184
68 4OAS 2SW 0.0009221 0.47053
69 1YP0 PEF 0.0002601 0.46881
70 1ZDT PEF 0.0001745 0.46808
71 1YUC EPH 0.00006113 0.46742
72 1SBR VIB 0.002766 0.46718
73 1A05 IPM 0.00347 0.46493
74 3FS1 ALA ALA LEU ALA ALA LEU LEU ALA ALA 0.003777 0.46452
75 4HW3 19G 0.001239 0.46433
76 4LWU 20U 0.001247 0.4642
77 1ZDT PEF 0.0001755 0.46415
78 2HHP FLC 0.001116 0.46353
79 3MG9 GHP 3MY 3FG GHP GHP OMY 3FG 0.00839 0.45994
80 3G9E RO7 0.00009946 0.45912
81 4HW3 19G 0.001136 0.45709
82 4RC7 PL3 0.0009406 0.45662
83 2VWA PTY 0.005919 0.45598
84 4QJR PIZ 0.0002812 0.45585
85 3F8C HT1 0.005395 0.45584
86 3KDU NKS 0.0001815 0.45479
87 3FEA ACE PHE MET AIB PM3 6CW GLU 1AC LEU NH2 0.003144 0.45388
88 3WBG 2AN 0.001841 0.45159
89 1YC4 43P 0.002925 0.45075
90 3KDU NKS 0.0002935 0.45047
91 3KDU NKS 0.0002935 0.45047
92 1HG4 LPP 0.0003154 0.45032
93 4IA6 EIC 0.006547 0.44921
94 1OSV CHC 0.001382 0.44904
95 1OSV CHC 0.001393 0.44888
96 2JC9 ADN 0.006351 0.44794
97 3BJC WAN 0.006643 0.4469
98 1YKD CMP 0.001926 0.44648
99 3WBG 2AN 0.002459 0.44564
100 1DB1 VDX 0.000222 0.44458
101 4F4S EFO 0.007616 0.44373
102 3RET PYR 0.003502 0.44251
103 3RET SAL 0.003502 0.44251
104 1K7L 544 0.0006105 0.44223
105 2BP1 FLC 0.01467 0.44197
106 2JHP GUN 0.005992 0.4419
107 1XVB 3BR 0.005579 0.44126
108 4RC7 PL3 0.003074 0.44105
109 1UO5 PIH 0.01306 0.44098
110 3B99 U51 0.004685 0.44061
111 4OAS 2SW 0.002162 0.44022
112 3HP9 CF1 0.01257 0.44001
113 1ID0 ANP 0.004915 0.43958
114 3WBG 2AN 0.00411 0.43913
115 2XRH NIO 0.009927 0.43874
116 1K7L 544 0.0007484 0.43864
117 4HW3 19G 0.001954 0.43843
118 1NQ7 ARL 0.001967 0.4383
119 2GBB CIT 0.009852 0.43776
120 4HBM 0Y7 0.008047 0.43766
121 4HBM 0Y7 0.008047 0.43766
122 2Z9I GLY ALA THR VAL 0.01117 0.43717
123 1YMT DR9 0.0001831 0.43655
124 3B9Z CO2 0.02159 0.4357
125 4EXO PYR 0.0116 0.43539
126 3KYQ DPV 0.0115 0.43417
127 3KP6 SAL 0.0179 0.43387
128 2YLD CMO 0.01454 0.43355
129 1LNX URI 0.0138 0.43327
130 3KO0 TFP 0.006653 0.43322
131 1ZDU P3A 0.001031 0.43301
132 1TV5 N8E 0.01609 0.43286
133 4B1V LAB 0.008223 0.4327
134 4ETZ C2E 0.01302 0.43238
135 1N4H REA 0.001902 0.43185
136 3EE4 MYR 0.002288 0.43182
137 3P9T TCL 0.008813 0.43117
138 4BVM PLM 0.002855 0.4311
139 4HW3 19G 0.00892 0.43091
140 1B56 PLM 0.01095 0.43069
141 3GFZ FMN 0.0076 0.4302
142 3KO0 TFP 0.007857 0.42976
143 3KO0 TFP 0.00774 0.4296
144 3JRS A8S 0.005412 0.42941
145 1HG4 LPP 0.001065 0.42929
146 1N83 CLR 0.001526 0.42926
147 1BRW URA 0.01618 0.42925
148 2BP1 FLC 0.02052 0.42894
149 1DTL BEP 0.008124 0.42876
150 3QP4 HL0 0.005659 0.42849
151 1K7L 544 0.001354 0.42821
152 1XX4 BAM 0.02666 0.42802
153 1XX4 BAM 0.02666 0.42802
154 3KO0 TFP 0.0176 0.42708
155 3GYT DL4 0.002069 0.42698
156 3RS8 ALA TRP LEU PHE GLU ALA 0.005093 0.4269
157 1ZPD CIT 0.02186 0.42687
158 4RC8 STE 0.002974 0.42686
159 3TL1 JRO 0.01577 0.42682
160 1SO2 666 0.00614 0.42681
161 2Z6C FMN 0.004289 0.42671
162 2P54 735 0.001516 0.42623
163 2VWA PTY 0.02076 0.42599
164 3TL1 JRO 0.01647 0.42581
165 4FLP JQ1 0.01712 0.42573
166 4HBM 0Y7 0.01129 0.4257
167 4HBM 0Y7 0.01129 0.4257
168 4EJ1 FOL 0.007794 0.42567
169 1TMX HGX 0.003171 0.42564
170 1G2N EPH 0.002244 0.4255
171 3JQM GTP 0.01402 0.42509
172 1H0A I3P 0.02095 0.42496
173 2OHV NHL 0.01415 0.42488
174 4R38 RBF 0.004745 0.42472
175 4HBM 0Y7 0.003366 0.42451
176 3W54 RNB 0.005807 0.42425
177 2XEM SSV 0.01208 0.42421
178 4HBM 0Y7 0.01211 0.42416
179 4HR0 PLM 0.001706 0.42415
180 3T50 FMN 0.004901 0.42408
181 4DS8 A8S 0.008405 0.42408
182 2YEM WSH 0.01916 0.42353
183 1XMY ROL 0.01527 0.42316
184 4BVM VCA 0.003618 0.42314
185 4I90 CHT 0.01986 0.42314
186 4HBM 0Y7 0.01293 0.4227
187 2QCX PF1 0.01993 0.42246
188 1XMY ROL 0.0158 0.42238
189 3GZ9 D32 0.0001986 0.42236
190 1SO2 666 0.007756 0.422
191 1XN0 ROL 0.0161 0.42196
192 1K7L 544 0.00236 0.42145
193 4HW3 19G 0.01994 0.42136
194 3BRN SRO 0.0208 0.42123
195 1XN0 ROL 0.0167 0.42112
196 4DW4 U5P 0.009766 0.42091
197 1FM9 570 0.001048 0.42076
198 1NQ7 HIS LYS ILE LEU HIS ARG LEU LEU GLN GLU 0.01714 0.42053
199 3T50 FMN 0.005878 0.42049
200 3T50 FMN 0.005878 0.42049
201 4R38 RBF 0.004979 0.42035
202 3G58 988 0.01442 0.42029
203 4HBM 0Y7 0.01456 0.42007
204 2VWA PTY 0.02512 0.41992
205 1N9L FMN 0.006094 0.41978
206 1N9L FMN 0.006094 0.41978
207 1N9L FMN 0.006094 0.41978
208 4N9Z V3L 0.01909 0.41977
209 2QQD AG2 0.02143 0.41968
210 4Q86 AMP 0.01044 0.41951
211 4Q86 AMP 0.01057 0.41924
212 4R38 RBF 0.00534 0.41899
213 4R38 RBF 0.00534 0.41899
214 1OW4 2AN 0.01544 0.41878
215 3MN5 LAB 0.02273 0.4183
216 4UYG 73B 0.02274 0.41829
217 3QP8 HL0 0.007853 0.41817
218 3E3U NVC 0.01113 0.41816
219 3G58 988 0.01589 0.41814
220 3W54 RNB 0.01117 0.41808
221 2QLX RM4 0.02317 0.41807
222 2QLX RM4 0.02317 0.41807
223 3LXI CAM 0.02408 0.41796
224 3JRS A8S 0.007973 0.41786
225 3IA4 MTX 0.01152 0.41743
226 2PX6 DH9 0.009749 0.41728
227 4UYG 73B 0.02377 0.41726
228 4UYG 73B 0.02482 0.41715
229 3LXI CAM 0.025 0.41701
230 3G58 988 0.01692 0.41675
231 4N14 WR7 0.0162 0.41668
232 3IX9 MTX 0.01446 0.41632
233 3BRN SRO 0.0256 0.41631
234 3NJQ NJQ 0.02488 0.41618
235 3NJQ NJQ 0.02488 0.41618
236 3NJQ NJQ 0.02488 0.41618
237 3KDJ A8S 0.007419 0.41589
238 3VV5 SLZ 0.01776 0.41568
239 3W54 RNB 0.01258 0.41556
240 2FP2 TSA 0.007563 0.41551
241 1FM4 DXC 0.003317 0.41551
242 4LH7 NMN 0.02792 0.41541
243 4UYG 73B 0.0258 0.41533
244 2WPX ACO 0.0078 0.4149
245 4NKW PLO 0.009267 0.41483
246 2WG9 OCA 0.02644 0.41476
247 4EJ1 FOL 0.01102 0.41476
248 1TZD ADP 0.02681 0.41473
249 2GBB CIT 0.02218 0.41467
250 4URN NOV 0.02663 0.4146
251 2X1L MET 0.02603 0.41455
252 4HW3 19G 0.01873 0.4145
253 4NKW PLO 0.009473 0.41438
254 4I67 G G G RPC 0.01888 0.41432
255 3G4G D71 0.008137 0.41407
256 4DYO SD4 0.02286 0.41398
257 4DYO SD4 0.02286 0.41398
258 1VPD TLA 0.03173 0.41392
259 2WDA L42 0.03345 0.41386
260 3IA4 MTX 0.01366 0.41384
261 2BYC FMN 0.01625 0.4138
262 1UA4 BGC 0.02341 0.41344
263 1UA4 GLC 0.02341 0.41344
264 4HW3 19G 0.01654 0.4134
265 3HR1 PF9 0.006086 0.41327
266 4EKQ NPO 0.01992 0.41312
267 4WT2 3UD 0.00614 0.4131
268 4R38 RBF 0.007253 0.41307
269 4R38 RBF 0.007253 0.41307
270 1C1X HFA 0.01683 0.41303
271 4HW3 19G 0.01426 0.41292
272 3B1M KRC 0.0002131 0.41277
273 1N13 AG2 0.0319 0.41264
274 2Z6D FMN 0.008798 0.41252
275 3RV5 DXC 0.009037 0.41225
276 3NMH PYV 0.01245 0.41224
277 3G4G D71 0.009042 0.41198
278 4UYG 73B 0.0298 0.41197
279 4HW3 19G 0.015 0.41186
280 3G4G D71 0.009128 0.41179
281 2X1L MET 0.0293 0.41156
282 3GXO MQA 0.02556 0.41144
283 3GXO MQA 0.02556 0.41144
284 2X1L MET 0.02898 0.41132
285 3G4G D71 0.009399 0.41121
286 4NB5 2JT 0.009478 0.41105
287 4N9Z V3L 0.02252 0.41095
288 4UYG 73B 0.03262 0.41044
289 2WG9 OCA 0.03218 0.41016
290 3HAV SRY 0.02276 0.41016
291 4HW3 19G 0.0164 0.40997
292 3ZCB ATP 0.01648 0.40986
293 4QBK 3NZ 0.02343 0.40952
294 2BYC FMN 0.01688 0.40936
295 1KYZ FER 0.03544 0.40935
296 1UOU CMU 0.01704 0.40916
297 4ETZ C2E 0.02884 0.40868
298 2WTN FER 0.02887 0.40866
299 3GXO MQA 0.02893 0.40861
300 3OGN 3OG 0.01504 0.40833
301 1Y79 LYS TRP 0.0293 0.40832
302 1MFI FHC 0.03373 0.40825
303 3LLI FAD 0.003636 0.40806
304 1X8D RNS 0.03546 0.40798
305 2FVK DUC 0.03745 0.40775
306 2EV1 OLA 0.00697 0.40769
307 4K10 NI9 0.03456 0.4075
308 2Y7P SAL 0.03631 0.40732
309 1L0I PSR 0.03748 0.40729
310 4M56 GLO 0.03729 0.40717
311 1GJW GLC 0.04157 0.40697
312 2QQC AG2 0.03707 0.40684
313 1N13 AG2 0.04135 0.40682
314 2Q4X HMH 0.03808 0.40656
315 3G4Q MCH 0.02282 0.40643
316 3RMK BML 0.03735 0.40642
317 1MT1 AG2 0.03804 0.40623
318 4EIL CB3 0.02723 0.40618
319 2WDQ CBE 0.04254 0.4059
320 2AEL SAZ 0.01235 0.40581
321 2AEL SAZ 0.01235 0.40581
322 4JWK CTN 0.04194 0.40567
323 1YRX FMN 0.01728 0.40545
324 3V78 ET 0.02393 0.4054
325 3KO0 TFP 0.04902 0.40537
326 4URN NOV 0.0335 0.40525
327 4DID GDP 0.02464 0.40477
328 1UO4 PIH 0.04961 0.40466
329 2IYG FMN 0.02521 0.40427
330 4FMJ SIA GAL 0.03661 0.40411
331 3OGN 3OG 0.01576 0.40409
332 3WJO IPE 0.0393 0.40408
333 2V0U FMN 0.01354 0.40399
334 2HFK E4H 0.04231 0.40372
335 2HFK E4H 0.04231 0.40372
336 1T0S BML 0.03237 0.40357
337 1T0S BML 0.03237 0.40357
338 2QQC AG2 0.04754 0.40349
339 1TIQ COA 0.02227 0.40348
340 3WAR NIO 0.03462 0.40334
341 3AQA BYH 0.04475 0.40328
342 3AQA BYH 0.04475 0.40328
343 1Q3A NGH 0.02253 0.40324
344 1BW9 PPY 0.02278 0.403
345 1C3R TSN 0.02677 0.40296
346 3KO0 TFP 0.03144 0.40282
347 4EIL CB3 0.03165 0.40282
348 1JU4 BEZ 0.04691 0.40271
349 3ROE THM 0.03759 0.40262
350 2ADA HPR 0.01698 0.40258
351 4HW3 19G 0.03203 0.40255
352 4K10 NI9 0.03815 0.40247
353 3JRX S1A 0.01718 0.40234
354 1RTW MP5 0.04506 0.40223
355 2IDO TMP 0.04709 0.40218
356 1BGV GLU 0.04614 0.40211
357 2PEH LYS ARG LYS SER ARG TRP ASP GLU THR PRO 0.0327 0.40209
358 1SQL GUN 0.03921 0.40154
359 4AQL TXC 0.01787 0.40154
360 3A23 GAL 0.04681 0.40133
361 3IX9 MTX 0.02108 0.40133
362 3PMD 11A 0.03395 0.40126
363 4EIL CB3 0.03406 0.40119
364 1XM4 PIL 0.02907 0.40117
365 3UNG ADP 0.0479 0.40112
366 4GBD MCF 0.01159 0.40103
367 1PNF NDG NAG 0.04895 0.40101
368 1XM4 PIL 0.02927 0.40101
369 3Q2H QHF 0.0158 0.40093
370 1WB4 SXX 0.0471 0.40074
371 4UYF 73B 0.04807 0.4007
372 2QEH SRO 0.04135 0.40043
373 3G58 988 0.01907 0.40022
374 1F1V DHY 0.04176 0.4002
375 2UXI G50 0.01644 0.40013
Feedback