Receptor
PDB id Resolution Class Description Source Keywords
1AGW 2.4 Å EC: 2.7.10.1 CRYSTAL STRUCTURE OF THE TYROSINE KINASE DOMAIN OF FIBROBLAST GROWTH FACTOR RECEPTOR 1 IN COMPLEX WITH SU4984 I NHIBITOR HOMO SAPIENS PROTEIN KINASE TRANSFERASE TYROSINE-PROTEIN KINASE ATP- BINDING PHOSPHORYLATION INHIBITOR
Ref.: STRUCTURES OF THE TYROSINE KINASE DOMAIN OF FIBROBLAST GROWTH FACTOR RECEPTOR IN COMPLEX WITH INHIBITORS. SCIENCE V. 276 955 1997
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
SU2 A:1001;
B:1000;
Valid;
Valid;
none;
none;
submit data
335.4 C20 H21 N3 O2 c1ccc...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4F65 2.26 Å EC: 2.7.10.1 CRYSTAL STRUCTURE OF HUMAN FIBROBLAST GROWTH FACTOR RECEPTOR DOMAIN IN COMPLEX WITH COMPOUND 8 HOMO SAPIENS KINASE ATP BINDING PHOSPHORYLATION TRANS-MEMBRANE TRANSFTRANSFERASE INHIBITOR COMPLEX
Ref.: PROTEIN-LIGAND CRYSTAL STRUCTURES CAN GUIDE THE DES SELECTIVE INHIBITORS OF THE FGFR TYROSINE KINASE. J.MED.CHEM. V. 55 5003 2012
Members (12)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 65 families.
1 3JS2 - VM1 C10 H7 N O2 S c1cc(sc1)c....
2 3RHX ic50 = 0.84 uM 3RH C18 H15 N3 c1ccc(cc1)....
3 4NKA Kd = 447 nM 2K7 C22 H25 N7 O3 Cc1cc(on1)....
4 2FGI Ki = 36.4 nM PD1 C28 H41 N7 O3 CCN(CC)CCC....
5 1FGI - SU1 C17 H16 N2 O3 Cc1c[nH]c(....
6 4V04 Kd = 7.7 nM 0LI C29 H27 F3 N6 O Cc1ccc(cc1....
7 4NKS Kd = 69.1 nM 2M2 C20 H21 N7 O Cc1cc(on1)....
8 3C4F ic50 = 1.9 uM C4F C15 H14 N2 O COc1cccc(c....
9 4F64 ic50 = 63 nM 0S8 C16 H20 Br N7 O2 Cc1cc(on1)....
10 1AGW - SU2 C20 H21 N3 O2 c1ccc2c(c1....
11 3WJ6 ic50 = 9.3 nM LWJ C20 H16 N6 O Cc1[nH]c2c....
12 4F65 ic50 = 2.5 nM 0S9 C20 H20 Br N7 O Cc1cc(on1)....
70% Homology Family (27)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 46 families.
1 3B2T - M33 C11 H17 N5 O9 P2 CP(=O)(O)O....
2 1OEC - AA2 C25 H30 Cl N5 O CC(C)(c1cc....
3 4J96 - ACP C11 H18 N5 O12 P3 c1nc(c2c(n....
4 2PWL - ACP C11 H18 N5 O12 P3 c1nc(c2c(n....
5 2PZP - ACP C11 H18 N5 O12 P3 c1nc(c2c(n....
6 4J98 - ACP C11 H18 N5 O12 P3 c1nc(c2c(n....
7 2PVY - ACP C11 H18 N5 O12 P3 c1nc(c2c(n....
8 3CLY - ACP C11 H18 N5 O12 P3 c1nc(c2c(n....
9 3RI1 ic50 = 1.23 uM 3RH C18 H15 N3 c1ccc(cc1)....
10 2PY3 - ACP C11 H18 N5 O12 P3 c1nc(c2c(n....
11 2PZ5 - ACP C11 H18 N5 O12 P3 c1nc(c2c(n....
12 4K33 - ACP C11 H18 N5 O12 P3 c1nc(c2c(n....
13 4TYJ - 0LI C29 H27 F3 N6 O Cc1ccc(cc1....
14 4UXQ Kd = 16 nM 0LI C29 H27 F3 N6 O Cc1ccc(cc1....
15 4QRC - 0LI C29 H27 F3 N6 O Cc1ccc(cc1....
16 3JS2 - VM1 C10 H7 N O2 S c1cc(sc1)c....
17 3RHX ic50 = 0.84 uM 3RH C18 H15 N3 c1ccc(cc1)....
18 4NKA Kd = 447 nM 2K7 C22 H25 N7 O3 Cc1cc(on1)....
19 2FGI Ki = 36.4 nM PD1 C28 H41 N7 O3 CCN(CC)CCC....
20 1FGI - SU1 C17 H16 N2 O3 Cc1c[nH]c(....
21 4V04 Kd = 7.7 nM 0LI C29 H27 F3 N6 O Cc1ccc(cc1....
22 4NKS Kd = 69.1 nM 2M2 C20 H21 N7 O Cc1cc(on1)....
23 3C4F ic50 = 1.9 uM C4F C15 H14 N2 O COc1cccc(c....
24 4F64 ic50 = 63 nM 0S8 C16 H20 Br N7 O2 Cc1cc(on1)....
25 1AGW - SU2 C20 H21 N3 O2 c1ccc2c(c1....
26 3WJ6 ic50 = 9.3 nM LWJ C20 H16 N6 O Cc1[nH]c2c....
27 4F65 ic50 = 2.5 nM 0S9 C20 H20 Br N7 O Cc1cc(on1)....
50% Homology Family (417)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 14 families.
1 1YWN ic50 ~ 0.003 uM LIF C27 H19 F4 N5 O3 COc1ccc(cc....
2 2OH4 ic50 = 3.5 nM GIG C23 H17 F4 N5 O4 COC(=O)Nc1....
3 4AG8 Ki = 1.1 nM AXI C22 H18 N4 O S CNC(=O)c1c....
4 3CJF ic50 = 6.3 nM SAV C21 H22 N6 O3 Cc1c2ccc(c....
5 3U6J - 03X C29 H25 F N4 O5 CC1=C(C(=O....
6 3CPC - C52 C21 H15 F3 N4 O CC1=C(C(=O....
7 3EWH ic50 = 69 nM K11 C28 H20 F3 N7 O CNc1nccc(n....
8 3CJG - KIM C22 H24 N6 O3 Cc1c2ccc(c....
9 3VO3 ic50 = 1.4 nM 0KF C22 H21 N7 O3 Cc1cc(n(n1....
10 3VNT ic50 = 2.2 nM 0JA C27 H19 Cl F N5 O3 S c1cc(c(c(c....
11 3C7Q ic50 = 21 nM XIN C31 H33 N5 O4 CN1CCN(CC1....
12 1Y6B ic50 = 38 nM AAX C25 H24 N4 O4 S COc1ccc(cc....
13 3VHE ic50 = 6.2 nM 42Q C21 H15 F4 N5 O2 Cn1ccc2c1c....
14 1Y6A ic50 = 0.022 uM AAZ C23 H21 N3 O4 S CCS(=O)(=O....
15 3IK3 ic50 = 2 nM 0LI C29 H27 F3 N6 O Cc1ccc(cc1....
16 3QRJ ic50 = 4 nM 919 C30 H28 F N7 O3 CC(C)(C)c1....
17 3UE4 - DB8 C26 H29 Cl2 N5 O3 CN1CCN(CC1....
18 3OY3 ic50 = 35.8 nM XY3 C29 H31 F3 N6 O3 Cc1ccc(cc1....
19 2E2B ic50 = 11 nM 406 C30 H31 F3 N8 O Cc1ccc(cc1....
20 2V7A Kd = 0.005 uM 627 C26 H30 N6 O3 CN1CCN(CC1....
21 2G2H Ki ~ 1 uM P16 C21 H16 Cl2 N4 O2 CN1c2c(cnc....
22 3QRI ic50 = 0.8 nM 919 C30 H28 F N7 O3 CC(C)(C)c1....
23 1FPU Ki = 37 nM PRC C22 H18 N6 O Cc1ccc(cc1....
24 3PYY - 3YY C18 H13 F N4 O2 c1ccc(cc1)....
25 1OPJ - MYR C14 H28 O2 CCCCCCCCCC....
26 3CS9 ic50 < 33 uM NIL C28 H22 F3 N7 O Cc1ccc(cc1....
27 3MSS - STI C29 H31 N7 O Cc1ccc(cc1....
28 3OXZ ic50 = 8.6 nM 0LI C29 H27 F3 N6 O Cc1ccc(cc1....
29 3KFA ic50 = 25 nM B91 C29 H25 F3 N8 O Cc1ccc(cc1....
30 3MS9 - MS9 C8 H8 Cl N O2 COC(=O)c1c....
31 2GQG - 1N1 C22 H26 Cl N7 O2 S Cc1cccc(c1....
32 2QOH - P3Y C22 H20 N4 O2 CN(C)C(=O)....
33 2HYY ic50 = 170 nM STI C29 H31 N7 O Cc1ccc(cc1....
34 2HZI ic50 = 70 nM JIN C21 H15 Cl2 F N4 O Cc1cc(ccc1....
35 3KF4 ic50 < 0.5 nM B90 C23 H22 N7 O P Cc1ccc2c(c....
36 3K5V - STI C29 H31 N7 O Cc1ccc(cc1....
37 2HZ0 ic50 = 330 nM GIN C23 H22 F3 N3 O2 CCCc1ccc(c....
38 1IEP ic50 = 100 nM STI C29 H31 N7 O Cc1ccc(cc1....
39 2F4J - VX6 C23 H28 N8 O S Cc1cc([nH]....
40 3QRK ic50 = 57 nM 9DP C24 H25 Cl2 N5 O3 CC(C)(C)c1....
41 2HIW ic50 = 8 nM 7MP C22 H18 F3 N6 O2 Cc1ccc(cc1....
42 2Z60 - P3Y C22 H20 N4 O2 CN(C)C(=O)....
43 3BZ3 ic50 = 1.5 nM YAM C21 H20 F3 N7 O3 S CN(c1c(ccc....
44 4GU9 Kd = 43 uM 4GU C11 H8 F N5 c1ccc(c(c1....
45 1MP8 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
46 4EBV ic50 = 0.99 uM 0O7 C18 H17 N3 O2 S CCc1ccc(cc....
47 2JKO ic50 = 7.7 nM BIJ C25 H28 Cl N7 O2 CN1CCN(CC1....
48 4I4E ic50 = 0.5 uM 1BQ C24 H26 N4 O4 S CN1c2ccc(c....
49 2JKK ic50 = 6.24 nM BI9 C23 H25 Cl N6 O3 CNC(=O)c1c....
50 2J0L - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
51 4I4F ic50 = 0.64 uM 1BR C22 H26 N4 O2 S CC(C)(C)c1....
52 4K9Y Kd = 0.111 uM K9Y C26 H27 N9 O Cc1ccc(cc1....
53 4Q9S ic50 = 156 uM 30G C10 H9 N3 O2 c1ccc2c(c1....
54 4BRX ic50 = 0.32 uM KGW C22 H25 N7 O3 CNC(=O)c1c....
55 4GU6 Kd = 44 nM 10N C22 H20 N6 O2 S CN(c1c(ccc....
56 4KAO Kd = 0.77 uM KAO C26 H27 N5 O Cc1ccc(cc1....
57 2JKM ic50 = 17.76 nM BII C25 H32 Cl N7 O3 S CC(C)NS(=O....
58 4C7T ic50 = 0.14 uM 5RI C20 H22 N6 O4 CNC(=O)c1c....
59 4CKR ic50 = 105 nM DI1 C30 H31 F3 N4 O3 CCN1CCN(CC....
60 3FQH ic50 = 0.57 uM 057 C21 H22 N4 O2 CC(C)(CO)N....
61 3FQS ic50 = 0.041 uM 585 C22 H23 F N6 O5 CC1(C(=O)N....
62 3TUC ic50 = 100 nM FPW C29 H24 N4 O5 COc1cc2c(c....
63 4DFL ic50 = 2.4 uM 0K0 C18 H24 N6 O3 S CS(=O)(=O)....
64 1XBC ic50 = 0.012 uM STU C28 H26 N4 O3 CC12C(C(CC....
65 4PUZ ic50 = 7.7 nM CG9 C23 H21 N7 O c1cc(ccc1N....
66 4I0R ic50 = 14 nM 1B4 C19 H22 N4 O4 CC(C)NC(=O....
67 3TUB ic50 = 320 nM FPU C26 H24 N4 O4 COc1cc2c(c....
68 1XBB Ki = 5 uM STI C29 H31 N7 O Cc1ccc(cc1....
69 4F4P ic50 = 0.6 nM 0SB C21 H20 F3 N5 c1cc(cc(c1....
70 4PV0 Kd = 4 nM CG4 C28 H23 N5 O5 COc1ccc(cc....
71 4FYO ic50 = 47 nM 0VF C25 H24 N6 O5 S COc1ccc(cc....
72 3FQE Ki = 0.02 uM P5C C18 H24 N6 O Cc1cccc(c1....
73 4FYN - 0VE C22 H23 N5 O2 CCN(CCO)c1....
74 4I0T ic50 = 26 nM 1B6 C18 H22 N6 O CC(C)(C)NC....
75 3VF8 ic50 = 150 nM 0JE C17 H21 F N6 O2 CCN(CC)C(=....
76 4FL1 Kd = 520 uM ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
77 4PX6 ic50 = 4 nM 2X6 C21 H23 N7 O c1cc2cc[nH....
78 3TUD ic50 = 2.1 nM FPX C29 H22 F3 N5 O2 Cc1ccc(cc1....
79 4FZ6 ic50 = 127 nM 0VG C22 H22 N6 CC1CCCN1c2....
80 4DFN ic50 = 0.04 uM 0K1 C25 H28 N6 O2 Cn1cc(cn1)....
81 4I0S ic50 = 36 nM 1B5 C18 H17 Cl N6 O CC(C)NC(=O....
82 3VF9 ic50 = 358.2 nM 477 C19 H19 F2 N3 O S CCC(CC)(c1....
83 2C0I - L1G C33 H39 N9 O2 Cn1c2ccccc....
84 3VRZ - VRZ C25 H26 N6 O c1ccc(cc1)....
85 3VS1 - VSA C24 H24 N6 O c1ccc(cc1)....
86 3VS6 - VSH C20 H26 N6 O3 CC(C)n1c2c....
87 1QCF - PP1 C16 H19 N5 Cc1ccc(cc1....
88 3VRY ic50 = 7.7 nM B43 C23 H22 N4 O c1ccc(cc1)....
89 3VS3 - VSE C29 H34 N6 O CN1CCN(CC1....
90 3B2T - M33 C11 H17 N5 O9 P2 CP(=O)(O)O....
91 1OEC - AA2 C25 H30 Cl N5 O CC(C)(c1cc....
92 4J96 - ACP C11 H18 N5 O12 P3 c1nc(c2c(n....
93 2PWL - ACP C11 H18 N5 O12 P3 c1nc(c2c(n....
94 2PZP - ACP C11 H18 N5 O12 P3 c1nc(c2c(n....
95 4J98 - ACP C11 H18 N5 O12 P3 c1nc(c2c(n....
96 2PVY - ACP C11 H18 N5 O12 P3 c1nc(c2c(n....
97 3CLY - ACP C11 H18 N5 O12 P3 c1nc(c2c(n....
98 3RI1 ic50 = 1.23 uM 3RH C18 H15 N3 c1ccc(cc1)....
99 2PY3 - ACP C11 H18 N5 O12 P3 c1nc(c2c(n....
100 2PZ5 - ACP C11 H18 N5 O12 P3 c1nc(c2c(n....
101 4FOC ic50 = 0.003 uM 0UU C28 H34 N4 O3 COC(=O)C1C....
102 3EYG ic50 = 1.6 nM MI1 C16 H20 N6 O CC1CCN(CC1....
103 4ANQ ic50 = 605 nM VGH C21 H22 Cl2 F N5 O CC(c1c(ccc....
104 4BB4 - 32W C23 H21 N5 O2 COCCNC(=O)....
105 2VWW ic50 = 0.24 uM 7X2 C20 H19 Cl N4 O5 COc1cc(cc(....
106 2XVD ic50 = 0.002 uM AS6 C26 H33 N5 O4 S Cc1ccc(cc1....
107 2VX1 ic50 = 0.22 uM 7X8 C18 H14 Cl N5 O3 c1cc(cc(c1....
108 2VWZ ic50 = 0.794 uM 7X6 C18 H16 Cl N5 O4 S CS(=O)(=O)....
109 2YN8 - STU C28 H26 N4 O3 CC12C(C(CC....
110 2VWV ic50 = 16 uM 7X3 C19 H20 Cl N5 O4 COc1ccc(cc....
111 2VX0 ic50 = 0.58 uM 7X7 C21 H20 Cl N5 O3 c1cc(cc(c1....
112 2VWY ic50 = 0.09 uM 7X5 C18 H15 Cl N4 O4 S CS(=O)(=O)....
113 4AW5 ic50 = 765 nM 30K C30 H31 N5 O2 CCN1CCC(CC....
114 2X9F ic50 = 0.061 uM X9F C18 H16 N6 O2 S CS(=O)(=O)....
115 2VWU ic50 = 0.35 uM 7X1 C24 H27 Cl N4 O4 COc1cc2c(c....
116 2VWX ic50 = 0.04 uM 7X4 C17 H14 Cl N5 O4 S c1cc(cc(c1....
117 3ZEW - STU C28 H26 N4 O3 CC12C(C(CC....
118 4F1T - H52 C16 H21 N3 O2 S Cc1cncc2c1....
119 1QPC - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
120 2OFV ic50 = 0.2 nM 242 C23 H17 F3 N4 O Cc1ccc(cc1....
121 2OFU ic50 ~ 3 uM 1N9 C37 H46 N6 O7 Cc1cccc(c1....
122 2OF2 ic50 = 0.081 uM 547 C25 H26 N4 O c1ccc(cc1)....
123 3KXZ ic50 = 0.035 uM 925 C28 H32 N6 O3 CC1(CC(CC(....
124 3BYS ic50 = 0.5 nM AM5 C31 H30 F3 N7 O2 Cc1ccc(cc1....
125 3MPM ic50 = 30 nM 5LK C23 H26 N6 O CN1CCN(CC1....
126 3B2W ic50 = 0.6 nM 9NH C31 H29 F4 N7 O3 Cc1ccc(cc1....
127 1QPJ - STU C28 H26 N4 O3 CC12C(C(CC....
128 3BYO ic50 = 7 nM AM9 C31 H30 N8 O Cc1cccc(c1....
129 2OG8 ic50 = 0.5 nM 1N8 C30 H31 F3 N6 O2 CCN(CC)CC(....
130 1QPE ic50 = 20 nM PP2 C15 H17 Cl N5 CC(C)(C)n1....
131 3BYU ic50 = 0.8 nM AM6 C32 H32 F3 N7 O2 Cc1ccc(cc1....
132 1QPD - STU C28 H26 N4 O3 CC12C(C(CC....
133 4C3F - 7KW C19 H15 N5 c1ccc(cc1)....
134 3BYM ic50 = 0.006 uM AM0 C25 H23 N7 O3 COc1cc(cc(....
135 2ZM1 ic50 = 220 nM KSF C18 H13 Cl N4 c1ccc(cc1)....
136 3DKC - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
137 4DEG ic50 = 6 nM 0JJ C19 H16 N8 O S Cc1cc(sn1)....
138 4GG5 ic50 = 0.93 nM 0J3 C22 H22 F3 N5 O2 CN1CCN(CC1....
139 3R7O - M61 C28 H32 N6 O5 S CN(CC1COCC....
140 4AP7 Ki = 0.011 uM F47 C17 H12 F N5 O c1cc(ccc1C....
141 3DKG - SX8 C18 H13 N7 S Cn1cc(cn1)....
142 3Q6W Kd = 27 nM Q6W C31 H30 N6 O2 c1ccnc(c1)....
143 3CD8 ic50 = 9 nM L5G C22 H17 N5 O2 COc1ccc2c(....
144 3ZXZ Ki = 0.005 uM KRW C19 H16 N8 O c1cc2cc(cc....
145 4EEV ic50 = 42 nM L1X C30 H22 F2 N6 O3 CC1=CC=C(C....
146 3RHK ic50 = 520 nM M97 C23 H16 N3 O2 c1ccc2c(c1....
147 4GG7 ic50 = 6.5 nM 0J8 C23 H21 F3 N8 O2 c1cc(cc(c1....
148 3ZZE Ki = 0.0013 uM 6XP C18 H18 Cl N3 O3 Cc1ccc(c2c....
149 3DKF ic50 = 4 nM SX8 C18 H13 N7 S Cn1cc(cn1)....
150 3U6I - 044 C30 H27 F N4 O5 CC1=C(C(=O....
151 4DEI ic50 = 1 nM 0JL C23 H22 N6 O3 S Cc1cc(sn1)....
152 3CTJ ic50 = 0.11 uM 320 C22 H16 F2 N4 O3 c1cc(ccc1C....
153 3QTI ic50 = 14 nM 3QT C20 H16 N6 Cn1cc(cn1)....
154 3CCN ic50 = 120 nM LKG C18 H14 N4 O c1ccc(cc1)....
155 3F66 ic50 = 0.9 uM IHX C20 H19 F3 N4 O CN1CCN(CC1....
156 2WD1 ic50 = 82 nM ZZY C14 H10 N4 O5 S c1ccc(c(c1....
157 3CE3 ic50 = 1.8 nM 1FN C25 H16 F2 N4 O3 c1cc(ccc1N....
158 2WKM ic50 = 9 nM PFY C32 H34 Cl2 N4 O4 S Cc1c([nH]c....
159 3I5N ic50 = 17 nM B2D C21 H17 N7 O COc1cc2c(c....
160 3LQ8 ic50 = 0.4 nM 88Z C34 H34 F2 N4 O6 COc1cc2c(c....
161 3ZCL Ki = 0.0101 uM 5TF C17 H19 N7 CC(C)Nc1cc....
162 4FOB ic50 = 0.005 uM 0US C30 H39 N5 O4 S C=CCNS(=O)....
163 4CQE Kd < 3 nM CQE C30 H28 F3 N5 O3 S2 CC(=O)Nc1c....
164 3OG7 - 032 C23 H18 Cl F2 N3 O3 S CCCS(=O)(=....
165 4GK3 - L87 C19 H21 N5 O2 CCCCn1c(cn....
166 4GK4 - L90 C20 H21 N7 O2 CCCCn1c(cn....
167 3FY2 - LYS GLN TRP ASP ASN TYR GLU PHE ILE TRP n/a n/a
168 3FXX - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
169 2QO7 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
170 4P5Q - Q0B C22 H22 Cl N5 O2 CCOCCCNC(=....
171 4P4C - 25Q C18 H15 N5 O2 COc1cccc(c....
172 2QOC - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
173 4P5Z Kd = 39.3 nM Q7M C25 H18 F3 N7 O2 c1ccc2c(c1....
174 4GK2 - L66 C22 H19 N5 O4 Cc1ccc(cc1....
175 2QO9 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
176 2QOQ - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
177 2XBA Ki = 23.68 nM 571 C25 H27 N6 O3 CN1CCN(CC1....
178 3LCS - STU C28 H26 N4 O3 CC12C(C(CC....
179 2XB7 Ki = 0.65 nM GUI C30 H40 Cl N7 O3 S CC(C)S(=O)....
180 2XP2 - VGH C21 H22 Cl2 F N5 O CC(c1c(ccc....
181 4FOD ic50 = 0.0012 uM 0UV C33 H44 F N5 O3 CC(C)NC(=O....
182 4FNY ic50 = 0.256 uM I3K C24 H18 Cl N3 O4 COc1cc2c(c....
183 3AOX Kd = 2.4 nM EMH C30 H34 N4 O2 CCc1cc2c(c....
184 1U59 ic50 = 55.8 nM STU C28 H26 N4 O3 CC12C(C(CC....
185 3U6H Ki = 1 nM 03X C29 H25 F N4 O5 CC1=C(C(=O....
186 1R0P Kd = 10 nM KSA C27 H21 N3 O5 CC12C(CC(O....
187 2RFS - AM8 C23 H22 Cl N3 O3 S Cc1c(c([nH....
188 3CTH ic50 = 0.035 uM 319 C20 H16 F2 N4 O3 c1cc(ccc1C....
189 3VW8 - DF6 C26 H23 N3 O4 S COc1cc2c(c....
190 3L8V ic50 = 0.008 uM L8V C23 H16 F3 N5 O2 c1cc(c(nc1....
191 4PMM ic50 = 662 nM 31V C27 H26 N8 O2 Cc1cn(cn1)....
192 1OPK - MYR C14 H28 O2 CCCCCCCCCC....
193 2FO0 - P16 C21 H16 Cl2 N4 O2 CN1c2c(cnc....
194 4CCU - AWF C22 H23 F N6 O2 S Cc1c(sc(n1....
195 3D94 ic50 = 118 nM D94 C30 H31 N7 CN1CCN(CC1....
196 3O23 ic50 = 0.5 uM MQY C21 H16 F3 N3 O4 S CC1C(=O)N(....
197 3NW6 ic50 = 7 nM LGW C22 H21 F N8 O c1cc2c(nc(....
198 2OJ9 ic50 = 0.39 uM BMI C22 H19 N7 O Cc1cc(cc2c....
199 3I81 ic50 = 13 nM EBI C23 H24 F N9 O CC1(CCCN1c....
200 3NW5 ic50 = 8400 nM LGX C22 H21 F N8 O c1cc2c(nc(....
201 1JQH - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
202 3NW7 ic50 = 5.3 nM LGV C19 H17 F N8 O c1cc2c(nc(....
203 4F1O - ACP C11 H18 N5 O12 P3 c1nc(c2c(n....
204 4AT3 ic50 = 0.004 uM LTI C16 H18 N4 O2 S2 c1ccc2c(c1....
205 2SRC - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
206 1Y57 ic50 = 1633 nM MPZ C28 H29 N7 O CN1CCN(CC1....
207 3BRB - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
208 2P0C - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
209 3W32 ic50 = 75 nM W32 C25 H23 Cl F3 N5 O4 S CS(=O)(=O)....
210 4I22 - IRE C22 H24 Cl F N4 O3 COc1cc2c(c....
211 2ITV - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
212 3VJN - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
213 3UG2 Kd = 5.6 nM IRE C22 H24 Cl F N4 O3 COc1cc2c(c....
214 3POZ ic50 = 23 nM 03P C26 H25 Cl F3 N5 O3 CC(C)(CC(=....
215 2RGP ic50 = 0.3 uM HYZ C24 H27 F N8 c1cc(cc(c1....
216 3W33 ic50 = 36 nM W19 C25 H22 Cl N5 O3 S c1cc(c2ccs....
217 2ITN - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
218 4RJ8 Ki = 17 nM 3QS C22 H28 N6 O COC1CCN(CC....
219 1XKK Ki = 3 nM FMM C29 H26 Cl F N4 O4 S CS(=O)(=O)....
220 3BEL ic50 = 0.014 uM POX C22 H22 F N7 O2 COCCON=Cc1....
221 3LPB ic50 = 42 nM NVB C24 H23 N3 O5 S CNS(=O)(=O....
222 4E4M Ki = 11 nM 0NH C15 H19 N5 O2 S CC1(CCN(CC....
223 4HGE Ki = 11.9 nM 15V C17 H13 Cl N6 O Cc1cc(n(n1....
224 2B7A ic50 = 1 nM IZA C18 H16 F N3 O CC(C)(C)c1....
225 3E63 ic50 = 1.6 uM 5B2 C13 H11 N3 c1ccc(cc1)....
226 4GFM Ki = 0.06 uM 0X2 C12 H8 Cl2 N2 O2 c1cc(c(c(c....
227 2XA4 ic50 < 0.003 uM AZ5 C14 H14 Cl F N8 Cc1cc([nH]....
228 3Q32 ic50 = 0.0018 uM J2I C23 H24 F2 N8 O2 Cc1cc([nH]....
229 3FUP ic50 = 21.7 nM MI1 C16 H20 N6 O CC1CCN(CC1....
230 4JI9 - 1M3 C26 H35 N7 O2 S Cc1cnc(nc1....
231 3JY9 Ki = 0.001 uM JZH C21 H15 N3 O2 c1ccc2c(c1....
232 3RVG ic50 = 5 nM 17P C22 H24 N6 O Cn1cc(cn1)....
233 3UGC - 046 C28 H30 F3 N7 O3 CC(=O)Nc1c....
234 3E62 ic50 = 40.9 uM 5B1 C7 H6 Br N3 c1cc2c(cc1....
235 3TJC ic50 = 0.031 uM 0TP C19 H20 N4 O2 S CNC(=O)c1c....
236 4IVA - 1J5 C17 H19 N5 O CC(c1nc2cn....
237 4D0X ic50 = 0.008 uM 953 C16 H11 Cl F3 N5 O c1cc(c(cc1....
238 4GMY Ki = 0.028 uM 0X5 C16 H13 Cl2 N3 O2 c1cc(c(c(c....
239 3IOK Ki = 0.0002 uM 1P6 C18 H16 F N7 CC(c1ccc(c....
240 4D0W ic50 = 0.02 uM VVQ C16 H14 Cl N5 O Cc1ccc(cc1....
241 4C61 ic50 = 0.004 uM LMM C17 H17 F N8 S Cc1csc2c1n....
242 4P7E - 2HB C21 H23 N5 O3 S c1cc(n2c(c....
243 3KRR ic50 = 0.48 nM DQX C27 H28 F2 N6 O c1cc(c2c(c....
244 4F09 Ki = 10 nM JAK C14 H17 N5 Cc1nc2cnc3....
245 4JIA Ki = 0.0006 uM 1K3 C24 H26 N6 O CN1CCN(CC1....
246 4D1S ic50 = 0.022 uM BJG C28 H30 Cl N7 O Cc1ccc(cc1....
247 4AQC ic50 = 0.9 nM 88A C23 H23 N5 O3 S CS(=O)(=O)....
248 3KCK Ki = 0.0008 uM 3KC C20 H12 Cl N3 O c1ccc2c(c1....
249 3E64 ic50 = 0.078 uM 5B3 C17 H20 N4 O2 S CC(C)(C)NS....
250 4AOI Ki = 0.004 uM 4K0 C19 H12 N8 c1cc2c(c[n....
251 4E1Z - 0MX C24 H17 Cl N4 O4 S c1cc(cc(c1....
252 4X3J - 3WR C21 H14 F4 N6 O2 c1cc(ccc1N....
253 2P4I ic50 = 317 nM MR9 C29 H27 F3 N6 O3 Cc1ccc(cc1....
254 2OO8 ic50 = 1 nM RAJ C29 H29 F3 N6 O Cc1ccc(cc1....
255 4GFO Ki = 0.24 uM 0X2 C12 H8 Cl2 N2 O2 c1cc(c(c(c....
256 4GJ3 Ki = 1.4 nM 0XP C17 H11 Cl2 F N4 O2 c1cnc(cc1N....
257 4GII Ki = 1.8 nM 0X6 C17 H12 Cl2 N4 O2 c1cnc(cc1N....
258 3NZ0 - IZA C18 H16 F N3 O CC(C)(C)c1....
259 4GJ2 Ki = 2.5 nM 0XH C16 H12 Cl2 F N3 O2 c1cc(c(c(c....
260 3NYX Ki = 32 nM TZ1 C16 H9 Cl N4 O S3 c1cc(sc1)C....
261 3LXP - IZA C18 H16 F N3 O CC(C)(C)c1....
262 4GVJ - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
263 4GIH Ki = 0.0048 uM 0X5 C16 H13 Cl2 N3 O2 c1cc(c(c(c....
264 3C1X ic50 = 0.045 uM CKK C27 H27 F2 N7 O3 c1cc(ccc1C....
265 4CLJ Ki = 0.1 nM 5P8 C21 H19 F N6 O2 CC1c2cc(cc....
266 3LXN Ki = 4.4 nM MI1 C16 H20 N6 O CC1CCN(CC1....
267 4PY1 - 2YK C17 H16 N6 O2 S Cn1cc(cn1)....
268 4FEQ ic50 = 1.1 uM 0T8 C24 H33 N7 O2 c1cnccc1CC....
269 4FF8 ic50 = 0.4 uM 14S C25 H34 N6 O3 COc1ccccc1....
270 4DEH ic50 = 612 nM 0JK C21 H17 N5 O c1ccc(cc1)....
271 4PMT ic50 = 997 nM 31Y C23 H23 N7 O c1cc(cnc1)....
272 4AT4 ic50 = 0.012 uM T6E C20 H13 F4 N5 O S c1cc(ccc1c....
273 3G6H ic50 = 4.6 nM G6H C32 H28 F3 N7 O4 Cc1ccc(cc1....
274 4FIC ic50 = 20 uM 0UL C11 H9 N5 c1ccc(cc1)....
275 1YOL - S03 C25 H27 N5 O2 COc1cccc(c....
276 3F3U ic50 < 1 uM 1AW C20 H23 N5 O CC(C)(C)c1....
277 3DQX - AMP C10 H14 N5 O7 P c1nc(c2c(n....
278 3U4W ic50 = 0.13 uM 08L C36 H46 N8 O8 c1ccc(cc1)....
279 4MXO Kd = 0.73 nM DB8 C26 H29 Cl2 N5 O3 CN1CCN(CC1....
280 3F6X - IHH C22 H19 N7 c1ccc2c(c1....
281 3G6G ic50 = 18 nM G6G C35 H37 N9 O2 Cc1ccc(cc1....
282 2BDJ ic50 = 0.00045 uM HET C26 H30 N5 O2 P CP(=O)(C)c....
283 3U51 ic50 = 25 uM 08X C38 H49 N9 O7 c1ccc(cc1)....
284 2BDF ic50 = 0.067 uM 24A C20 H28 N6 O5 P2 CCn1cnc2c1....
285 3F3T ic50 = 64.1 uM 1AU C24 H25 N5 O CC(C)(C)c1....
286 3GEQ - PP2 C15 H17 Cl N5 CC(C)(C)n1....
287 3EN6 ic50 = 0.235 uM KS5 C17 H16 N6 CC(C)n1c2c....
288 3EL8 ic50 = 25 nM PD5 C22 H20 F3 N7 O CC(C)n1c2c....
289 3UQG - B5A C11 H16 N6 c1c2c(ncnc....
290 3UQF Ki = 0.2 uM BK5 C20 H21 N5 O CCOc1ccc2c....
291 4U5J ic50 = 2.92 uM RXT C17 H18 N6 c1c[nH]c2c....
292 4LGG ic50 = 4 nM VGG C17 H21 N5 Cc1cccc(c1....
293 3G5D ic50 = 0.0004 uM 1N1 C22 H26 Cl N7 O2 S Cc1cccc(c1....
294 3DQW - AGS C10 H16 N5 O12 P3 S c1nc(c2c(n....
295 2OIQ Kd = 42 uM STI C29 H31 N7 O Cc1ccc(cc1....
296 4IWD ic50 = 1 nM 1JC C29 H28 N6 O3 S c1ccnc(c1)....
297 3F82 ic50 = 3.9 nM 353 C25 H19 Cl F2 N4 O4 CCOC1=C(C(....
298 4H1J ic50 = 1200 nM 0YH C26 H30 N6 O2 Cc1ccc(cc1....
299 4H1M ic50 = 78 nM 0YJ C27 H32 N6 O2 Cc1ccc(cc1....
300 3FZT ic50 = 637 nM 4JZ C24 H27 N7 O2 Cc1ccc(cc1....
301 3FZP - AGS C10 H16 N5 O12 P3 S c1nc(c2c(n....
302 3H3C ic50 = 140 nM P1E C19 H25 F3 N6 O2 S CNS(=O)(=O....
303 3FZS ic50 = 1.5 uM B96 C31 H37 N5 O3 Cc1ccc(cc1....
304 3EYH ic50 = 20 nM IZA C18 H16 F N3 O CC(C)(C)c1....
305 3EKK ic50 = 2 nM GS2 C27 H27 F N8 O3 CNC(=O)c1c....
306 4IBM ic50 = 1.8 uM IR1 C18 H10 N6 O c1ccc(cc1)....
307 1I44 - ACP C11 H18 N5 O12 P3 c1nc(c2c(n....
308 3EKN ic50 = 2 nM GS3 C27 H31 F N8 O2 CC(C)N1CCN....
309 3G0E Kd = 20 nM B49 C22 H27 F N4 O2 CCN(CC)CCN....
310 4U0I ic50 < 11 nM 0LI C29 H27 F3 N6 O Cc1ccc(cc1....
311 4HVS ic50 = 0.016 uM 647 C21 H17 F3 N4 c1cc2c(c[n....
312 1T46 - STI C29 H31 N7 O Cc1ccc(cc1....
313 2P2H ic50 = 68 nM 994 C23 H22 N6 O3 COc1cc(cc(....
314 3KRL ic50 = 0.8 nM KRL C22 H27 N5 O2 CN1CCN(CC1....
315 3BEA ic50 = 0.003 uM IXH C29 H31 N7 O2 CC1CN(CC(N....
316 3DPK ic50 = 4.1 nM 8C5 C27 H34 N6 O3 CONC(=O)C1....
317 2I1M - 5CN C19 H21 N3 O3 CC1CCN(CC1....
318 3KRJ ic50 = 1 nM KRJ C22 H25 N5 O c1cc(c(cc1....
319 3LCD ic50 = 40 nM BDY C27 H30 Cl2 N6 O c1cc(c(c(c....
320 2I0Y - 5CN C19 H21 N3 O3 CC1CCN(CC1....
321 4AT5 ic50 = 0.038 uM MUJ C20 H22 N4 O3 COc1ccc(cc....
322 3ZBF Ki = 2.1 nM VGH C21 H22 Cl2 F N5 O CC(c1c(ccc....
323 3QUP ic50 = 0.476 uM LUN C25 H27 F N4 O c1ccc2c(c1....
324 4K33 - ACP C11 H18 N5 O12 P3 c1nc(c2c(n....
325 3CP9 - C19 C24 H23 N5 O CC1=C(C(=O....
326 3BE2 ic50 = 2 nM RAJ C29 H29 F3 N6 O Cc1ccc(cc1....
327 2H8H ic50 = 2.7 nM H8H C27 H32 Cl N5 O5 CN1CCN(CC1....
328 3MIY Kd = 21 nM B49 C22 H27 F N4 O2 CCN(CC)CCN....
329 4M14 - QWS C18 H19 N5 O3 CC(C)Oc1cc....
330 3QGW Ki = 1.3 uM L7A C17 H13 N3 O2 c1ccc(cc1)....
331 3V8W ic50 = 8.6 nM 0G2 C24 H23 N3 O S CCC(CC)(c1....
332 3V8T ic50 = 0.3 nM 477 C19 H19 F2 N3 O S CCC(CC)(c1....
333 3V5L ic50 = 7 nM 0G1 C25 H25 N3 O2 S CCC(CC)(c1....
334 4L7S Ki = 15.8 nM G7K C24 H23 F3 N6 O2 S COc1ccc2c(....
335 4M12 Kd = 0.9 uM 1YZ C17 H17 N5 O3 CCOc1ccc2c....
336 4M15 - QWS C18 H19 N5 O3 CC(C)Oc1cc....
337 4PQN Ki = 0.7 nM 2W6 C24 H32 N6 O CC1(CCc2c(....
338 4M0Z Kd = 6.4 uM M0Z C16 H15 N5 O3 COc1ccc2cc....
339 4KIO ic50 = 0.5 uM G5K C22 H26 N8 O2 S C=CC(=O)N1....
340 4MF1 Ki = 1.9 nM 29Y C23 H23 N5 O S CN(C)Cc1cc....
341 4M13 Kd = 0.2 uM 1E0 C18 H19 N5 O3 CCCOc1ccc2....
342 1SNU - STU C28 H26 N4 O3 CC12C(C(CC....
343 3QGY Ki = 0.016 uM L7O C22 H24 N6 O2 CNc1nccc(n....
344 1SM2 Ki < 10 nM STU C28 H26 N4 O3 CC12C(C(CC....
345 3MJ1 Kd = 2.1 nM 614 C23 H31 N7 O2 Cc1cc([nH]....
346 3MJ2 Kd = 15 nM MJG C32 H41 N5 O4 S2 Cc1cc(c(cc....
347 4M0Y Kd = 8.2 uM M0Y C15 H13 N5 O2 c1ccc2c(c1....
348 3PJC ic50 = 27 nM PJC C22 H16 F3 N5 O3 c1ccc2c(c1....
349 4HVH ic50 = 19 nM 19R C15 H20 N4 O2 CC(C(C)(C)....
350 3ZEP ic50 = 0.022 uM 1NX C23 H25 N5 O3 CC(C1CC1)N....
351 4I6Q ic50 = 0.03 uM 1DT C18 H18 N4 O2 CC(C1CC1)N....
352 3LXK Ki = 0.2 nM MI1 C16 H20 N6 O CC1CCN(CC1....
353 3ZC6 ic50 = 0.6 nM VFC C22 H19 F N8 O2 CC(C(=O)N1....
354 4HVD ic50 = 1.4 nM 933 C16 H22 N4 O CC(C(C)(C)....
355 3LXL - IZA C18 H16 F N3 O CC(C)(C)c1....
356 4HVI ic50 = 68.9 nM 19S C18 H23 N5 O2 CC(C(=O)N1....
357 3EQP - T95 C33 H38 N6 O4 CCOc1ccccc....
358 1U4D - DBQ C11 H11 N5 O2 c1c[nH]c2c....
359 3EQR Ki = 0.002 uM T74 C29 H38 N8 O Cc1cccc(c1....
360 4TYJ - 0LI C29 H27 F3 N6 O Cc1ccc(cc1....
361 4UXQ Kd = 16 nM 0LI C29 H27 F3 N6 O Cc1ccc(cc1....
362 4QRC - 0LI C29 H27 F3 N6 O Cc1ccc(cc1....
363 2HK5 ic50 = 46 nM 1BM C24 H29 N7 O CCN(CC)CCN....
364 4F0F - ACP C11 H18 N5 O12 P3 c1nc(c2c(n....
365 4ASE Ki = 0.01 nM AV9 C22 H19 Cl N4 O5 CC1=CC(=NC....
366 4AGC Ki = 0.02 nM AXI C22 H18 N4 O S CNC(=O)c1c....
367 4ASD Ki = 0.52 nM BAX C21 H16 Cl F3 N4 O3 CNC(=O)c1c....
368 1BYG - STU C28 H26 N4 O3 CC12C(C(CC....
369 4PMP ic50 = 4233 nM 31W C21 H18 F3 N3 O2 S c1cc(cc(c1....
370 1JPA - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
371 3PLS - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
372 4CTB - KVC C23 H18 F N7 O2 CC1c2cc(cc....
373 3JS2 - VM1 C10 H7 N O2 S c1cc(sc1)c....
374 3RHX ic50 = 0.84 uM 3RH C18 H15 N3 c1ccc(cc1)....
375 4NKA Kd = 447 nM 2K7 C22 H25 N7 O3 Cc1cc(on1)....
376 2FGI Ki = 36.4 nM PD1 C28 H41 N7 O3 CCN(CC)CCC....
377 1FGI - SU1 C17 H16 N2 O3 Cc1c[nH]c(....
378 4V04 Kd = 7.7 nM 0LI C29 H27 F3 N6 O Cc1ccc(cc1....
379 4NKS Kd = 69.1 nM 2M2 C20 H21 N7 O Cc1cc(on1)....
380 3C4F ic50 = 1.9 uM C4F C15 H14 N2 O COc1cccc(c....
381 4F64 ic50 = 63 nM 0S8 C16 H20 Br N7 O2 Cc1cc(on1)....
382 1AGW - SU2 C20 H21 N3 O2 c1ccc2c(c1....
383 3WJ6 ic50 = 9.3 nM LWJ C20 H16 N6 O Cc1[nH]c2c....
384 4F65 ic50 = 2.5 nM 0S9 C20 H20 Br N7 O Cc1cc(on1)....
385 2IVS - ACK C10 H12 N5 O6 P c1nc(c2c(n....
386 2X2L ic50 = 5.3 uM X2L C16 H14 N2 O2 COc1ccc(cc....
387 2IVV - PP1 C16 H19 N5 Cc1ccc(cc1....
388 4CKI - ADN C10 H13 N5 O4 c1nc(c2c(n....
389 2IVU Ki = 375 nM ZD6 C22 H24 Br F N4 O2 CN1CCC(CC1....
390 4CKJ - ADN C10 H13 N5 O4 c1nc(c2c(n....
391 2X2M ic50 = 0.17 uM X2M C15 H14 N2 O Cc1cc([nH]....
392 1MQB - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
393 3SXR - 1N1 C22 H26 Cl N7 O2 S Cc1cccc(c1....
394 3SXS - PP2 C15 H17 Cl N5 CC(C)(C)n1....
395 4CLI Ki < 0.07 nM 5P8 C21 H19 F N6 O2 CC1c2cc(cc....
396 4CCB - OFG C19 H18 F N7 O Cc1c(c[nH]....
397 4CMT Ki < 0.2 nM GWH C22 H22 F N5 O3 S CC(c1cc(cc....
398 4CTC - J99 C23 H24 F N5 O2 CC1c2cc(cc....
399 3PIZ ic50 = 3.5 uM 03C C23 H26 N4 O3 S Cc1ccccc1n....
400 4RG0 ic50 = 50 nM 3P0 C36 H38 F N7 O3 CC(C)(C#N)....
401 3GEN - B43 C23 H22 N4 O c1ccc(cc1)....
402 4NWM ic50 = 0.038 uM 2P5 C34 H35 N7 O3 Cc1c(cccc1....
403 4RFY ic50 = 100 nM 3OU C34 H36 N6 O5 CN1C=C(C=C....
404 4OT5 - 481 C35 H37 N7 O2 CC(C)(C)c1....
405 4OTQ - 2V2 C27 H29 N5 O3 Cc1c(cccc1....
406 3PJ3 ic50 = 5.6 uM 04L C29 H23 N5 O2 Cc1ccc(cc1....
407 3PJ1 ic50 = 0.048 uM LHL C25 H28 Cl2 N6 O2 CCN(CC)CCO....
408 4RFZ ic50 = 40 nM 3OV C34 H33 F N6 O5 CN1C=C(C=C....
409 3PIX ic50 = 0.1 uM 027 C20 H27 N7 O Cc1cc(n[nH....
410 3PJ2 ic50 = 7.2 uM 04K C26 H28 F N5 O3 CCN(CC)CCO....
411 4OT6 - 2V1 C31 H28 N6 O5 S CS(=O)(=O)....
412 4OTR - 2V3 C36 H37 F N6 O3 CCN1CCN(CC....
413 3K54 - 1N1 C22 H26 Cl N7 O2 S Cc1cccc(c1....
414 2XYU ic50 = 4.5 uM Q9G C17 H17 F N4 Cc1ccc(cc1....
415 2Y6O ic50 = 25 nM 1N1 C22 H26 Cl N7 O2 S Cc1cccc(c1....
416 4CMO Ki = 0.85 nM YPW C20 H20 F N5 O3 CC(c1cc(cc....
417 4CMU Ki < 0.2 nM IV7 C21 H22 F N5 O2 Cc1c-2c(n(....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SU2; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 SU2 1 1
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4F65; Ligand: 0S9; Similar sites found: 569
This union binding pocket(no: 1) in the query (biounit: 4f65.bio1) has 41 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc)
1 2VN9 GVD 3.905e-09 0.79339
2 2VN9 GVD 4.284e-09 0.77804
3 3H9R TAK 1.476e-08 0.74957
4 2NRY STU 2.16e-09 0.74732
5 2F57 23D 3.595e-09 0.747
6 4C2W ANP 1.162e-08 0.7433
7 2V7O DRN 2.087e-08 0.7416
8 2WEL K88 5.18e-08 0.74075
9 2OIC STU 7.704e-09 0.73064
10 2EVA ADN 3.087e-11 0.73054
11 4HNF 16W 2.274e-08 0.72821
12 4C2W ANP 8.594e-08 0.72758
13 4X2K 3WO 9.809e-09 0.72545
14 4X2J 3WN 9.809e-09 0.72545
15 2OIC STU 1.585e-08 0.72541
16 3GGF GVD 9.864e-09 0.72533
17 3GGF GVD 9.864e-09 0.72533
18 2WEI VGG 1.075e-08 0.72349
19 2OIC STU 2.19e-08 0.71831
20 4X0M 3WA 1.912e-07 0.71643
21 3GGF GVD 2.537e-08 0.71509
22 3HMO STU 1.043e-08 0.71422
23 4OTH DRN 1.072e-08 0.71363
24 1XJD STU 8.121e-09 0.70996
25 2QLU ADE 2.457e-07 0.70909
26 4BFM ANP 4.191e-09 0.70538
27 3BI6 396 2.712e-09 0.70534
28 4CFU 2WC 4.683e-08 0.70163
29 1O9U ADZ 5.43e-07 0.69979
30 2ZV2 609 8.133e-08 0.69958
31 2O2U 738 3.332e-08 0.69918
32 3TKI S25 1.613e-09 0.69884
33 4HNF 16W 2.231e-08 0.69823
34 4C58 824 2.944e-08 0.69239
35 2F2U M77 1.151e-07 0.69177
36 3M2W L8I 7.639e-08 0.69088
37 2J51 DKI 3.176e-08 0.6908
38 2A19 ANP 1.215e-07 0.69057
39 3SRV S19 3.378e-08 0.6895
40 4LOO SB4 2.222e-08 0.68923
41 4BCN T9N 5.629e-08 0.68792
42 3SRV S19 6.039e-08 0.68641
43 2NRU T12 4.107e-08 0.68539
44 1V0O INR 2.828e-08 0.68427
45 4FL3 ANP 8.195e-09 0.68386
46 2F2U M77 1.674e-07 0.68336
47 2NRY STU 4.678e-08 0.68266
48 4BHN BH9 1.017e-08 0.67967
49 4GRB 0XG 2.013e-07 0.67922
50 2Z7R STU 1.076e-08 0.67858
51 4C4F 7CE 1.862e-08 0.67586
52 1V0O INR 3.02e-08 0.6744
53 4AUA 4AU 6.439e-07 0.67295
54 2OIC STU 1.738e-07 0.67283
55 1VJY 460 2.933e-09 0.67271
56 4AU8 Z3R 2.701e-07 0.67261
57 4AU8 Z3R 2.701e-07 0.67261
58 2NRY STU 7.897e-08 0.67165
59 4IDT T28 7.903e-08 0.67163
60 4I6H 1C8 5.367e-08 0.67107
61 3A7H ATP 8.461e-08 0.6702
62 3A7H ATP 8.461e-08 0.6702
63 2VZ6 FEF 2.021e-07 0.66952
64 2NRY STU 1.333e-07 0.6694
65 4GW8 3RA 3.597e-07 0.66618
66 4H3P ANP 7.335e-08 0.66464
67 3IGO ANP 2.212e-08 0.66458
68 3TXO 07U 1.699e-07 0.66418
69 3TXO 07U 1.699e-07 0.66418
70 3RGF BAX 1.051e-08 0.66374
71 3C0G 3AM 9.535e-07 0.66369
72 2WTV ZZL 1.569e-08 0.66359
73 1U5R ATP 1.18e-07 0.66321
74 1U5R ATP 1.18e-07 0.66321
75 4H3P ANP 8.949e-08 0.66054
76 4CFU 2WC 2.017e-07 0.6605
77 4KBC 1QJ 3.275e-07 0.65892
78 3UYT 0CK 7.162e-08 0.65697
79 2NRU T12 7.408e-08 0.65629
80 3UZP 0CK 8.272e-08 0.65406
81 3UZP 0CK 8.272e-08 0.65406
82 4JQE ANP 1.235e-07 0.6539
83 3F7Z 34O 4.213e-07 0.65339
84 4OTI MI1 1.278e-07 0.6532
85 2WTV ZZL 3.988e-08 0.65313
86 3UYT 0CK 8.841e-08 0.65272
87 2J7T 274 2.995e-09 0.6519
88 4EYM 0RX 6.877e-08 0.65
89 4C2V YJA 3.426e-09 0.64959
90 2J90 IZA 1.689e-07 0.64746
91 4AU8 Z3R 8.307e-07 0.64736
92 3F7Z 34O 2.644e-07 0.64624
93 3CY2 MB9 8.885e-07 0.64585
94 3E5A VX6 2.082e-08 0.64399
95 3DAK ANP 4.464e-07 0.64344
96 1U5R ATP 2.191e-07 0.64209
97 4MBI 26K 1.072e-06 0.64164
98 4K1B 1OC 3.331e-07 0.64139
99 2OID ANP 1.55e-07 0.64138
100 4IVB 1J5 5.181e-07 0.64024
101 2WU6 DKI 5.702e-08 0.63899
102 2WTV ZZL 8.373e-08 0.63873
103 3A7H ATP 3.476e-06 0.63834
104 4K77 1Q4 1.888e-06 0.63794
105 3TTI KBI 1.841e-07 0.63792
106 3HZT J60 1.298e-06 0.63734
107 2OID ANP 2.886e-07 0.63643
108 2VAG V25 3.091e-07 0.63501
109 2RIO ADP 4.602e-07 0.63459
110 4BCN T9N 1.099e-06 0.63233
111 2OID ANP 7.831e-07 0.63136
112 4OAC ADP 3.786e-07 0.63084
113 4OAV ACP 5.902e-07 0.62936
114 3UZP 0CK 4.084e-07 0.62928
115 4BCQ TJF 2.756e-06 0.62923
116 2B9J ADP 5.986e-07 0.62906
117 2B9I ADP 4.143e-07 0.62898
118 3GC8 B45 1.007e-07 0.62815
119 4IVC 1J6 3.06e-07 0.62766
120 4EI4 0Q2 1.378e-06 0.62737
121 3V8S 0HD 6.532e-07 0.62723
122 4BHN BH9 7.407e-08 0.62719
123 4N6Z 2HW 1.405e-06 0.62693
124 4NFN 2KC 6.688e-07 0.62673
125 4KBC 1QJ 1.436e-06 0.62646
126 4KBC 1QJ 1.436e-06 0.62646
127 3V8S 0HD 7.068e-07 0.62557
128 2VZ6 FEF 2.211e-06 0.62537
129 4EI4 0Q2 1.512e-06 0.62533
130 3UYT 0CK 3.478e-07 0.62507
131 3FI3 JK2 3.526e-07 0.62479
132 3DAK ANP 5.184e-07 0.62436
133 3DAK ANP 5.184e-07 0.62436
134 4IVB 1J5 7.902e-07 0.62322
135 4K77 1Q4 2.442e-06 0.62313
136 4F1M ACP 1.194e-06 0.6223
137 4N70 2HX 1.76e-06 0.62199
138 4OA2 ADP 4.76e-07 0.61874
139 3JPV 1DR 6.47e-06 0.61852
140 4IVC 1J6 4.953e-07 0.61794
141 2NRU T12 3.71e-07 0.61663
142 4KBA 1QM 1.082e-06 0.61661
143 4EHZ JAK 2.333e-06 0.6158
144 4JDI ANP 3.876e-07 0.61577
145 3C0G 3AM 3.509e-06 0.61499
146 2NRU T12 1.016e-06 0.6105
147 4I94 ANP 2.075e-06 0.61044
148 4IVD 15T 5.12e-07 0.61026
149 4MWH ATP 5.145e-07 0.61016
150 4MWH ATP 5.145e-07 0.61016
151 2B9F ADP 1.046e-06 0.60991
152 4KBA 1QM 1.064e-06 0.60955
153 3GC0 AMP 3.16e-06 0.60914
154 4IVD 15T 5.484e-07 0.6089
155 3GC8 B45 3.906e-07 0.60881
156 4C2V YJA 2.75e-08 0.60804
157 4E6D 0NU 8.802e-07 0.60633
158 4EHZ JAK 3.794e-06 0.60513
159 1Q8Y ADE 7.975e-06 0.60478
160 4E4N 0NL 1.016e-06 0.60343
161 4BCQ TJF 5.97e-06 0.60305
162 3OFM 4B0 1.43e-05 0.603
163 4KBA 1QM 4.26e-06 0.60258
164 4H3Q ANP 3.906e-07 0.60231
165 1Q8Y ADP 7.992e-07 0.60144
166 4EHZ JAK 4.668e-06 0.60057
167 4NW6 2NS 3.101e-08 0.60048
168 4G31 0WH 1.665e-06 0.60034
169 3ZRM ZRM 1.726e-06 0.59959
170 2R5T ANP 6.397e-07 0.59923
171 2R5T ANP 6.397e-07 0.59923
172 4I94 ANP 2.586e-06 0.59829
173 4EHZ JAK 5.217e-06 0.59813
174 2YAK OSV 7.026e-08 0.59766
175 4E4N 0NL 1.927e-06 0.59732
176 3SLS ANP 7.478e-07 0.5962
177 4KBA 1QM 2.11e-06 0.59545
178 4KBA 1QM 2.11e-06 0.59545
179 3UYT 0CK 1.634e-06 0.59384
180 4E4L 0NH 4.573e-06 0.59346
181 4QTB 38Z 1.265e-07 0.59306
182 1XR1 ANP 1.744e-06 0.59253
183 4MK0 29X 4.818e-07 0.59213
184 4FG8 ATP 1.288e-06 0.592
185 4F9A ADP 3.619e-06 0.59123
186 4F9B 0SY 2.31e-05 0.59071
187 4E4L 0NH 5.27e-06 0.59042
188 3SLS ANP 1.018e-06 0.59021
189 4MQ1 2C3 1.458e-06 0.58954
190 3FHR P4O 2.076e-06 0.58901
191 4PNI KQQ 1.651e-07 0.58841
192 4MQ1 2C3 2.204e-06 0.5878
193 4EQC XR1 4.847e-08 0.5878
194 4F9A ADP 4.337e-06 0.58742
195 4JR7 GNP 6.392e-06 0.58627
196 4E6Q 0NV 2.391e-06 0.58616
197 2WQN ADP 9.082e-06 0.58596
198 4OH4 ANP 2.513e-06 0.58516
199 4QTB 38Z 1.99e-07 0.58515
200 2R5T ANP 9.704e-07 0.58496
201 3GNI ATP 1.862e-06 0.5847
202 4KS7 X4Z 1.01e-06 0.5842
203 4E6Q 0NV 2.008e-06 0.58321
204 4F9B 0SY 3.201e-05 0.58284
205 4QTC 38Z 5.962e-07 0.58229
206 4E4L 0NH 5.538e-06 0.58228
207 4F9C 0SX 6.363e-06 0.57936
208 3C0I 3AM 1.844e-06 0.57868
209 4MQ1 2C3 2.697e-06 0.57737
210 4F99 ADP 7.135e-06 0.57695
211 1ZTH ADP 1.968e-05 0.57625
212 1ZTH ADP 2.212e-05 0.57362
213 2XNM WGZ 2.948e-07 0.57301
214 2XK9 XK9 6.622e-08 0.57281
215 4TWC 37J 8.72e-06 0.57274
216 1ZTH ADP 2.34e-05 0.57236
217 3PVW QRX 7.715e-07 0.57199
218 4FG8 ATP 2.702e-06 0.57125
219 4JX7 1N6 1.913e-05 0.5696
220 2CSN CKI 9.271e-07 0.56867
221 3UIM ANP 8.018e-06 0.56796
222 3ALN ANP 4.805e-06 0.56594
223 4TW9 386 1.25e-05 0.56517
224 4OH4 ANP 9.458e-06 0.56456
225 3SXF BK5 1.494e-07 0.56454
226 2OID ANP 1.292e-05 0.56447
227 3MB6 01I 6.852e-05 0.5642
228 2PZI AXX 2.482e-05 0.56388
229 4EUU BX7 1.217e-06 0.56375
230 4MQ1 2C3 3.991e-06 0.56368
231 3OWL 19E 6.009e-05 0.56312
232 4IZY 1J2 5.625e-06 0.56282
233 4FK6 0UJ 1.42e-05 0.56248
234 4FK6 0UJ 1.449e-05 0.56206
235 3THB 3TA 1.445e-07 0.56041
236 3THB 3TA 1.445e-07 0.56041
237 3ALN ANP 4.014e-05 0.56024
238 4TWC 37J 8.989e-06 0.55943
239 3IDB ANP 3.879e-06 0.55854
240 2PVN P63 1.014e-06 0.5567
241 4KWP EXX 9.636e-05 0.55597
242 3E7O 35F 8.081e-09 0.55538
243 2PZI AXX 3.73e-05 0.55493
244 3RE4 TO1 2.102e-05 0.55423
245 3OWK 18E 0.0001066 0.55341
246 1ZTH ADP 4.121e-05 0.55275
247 4E93 GUI 5.746e-07 0.55188
248 3E7O 35F 8.485e-09 0.55059
249 4LRJ ANP 2.733e-05 0.54872
250 3ALN ANP 2.756e-05 0.54854
251 2JLD AG1 7.161e-07 0.54822
252 3ORK AGS 4.012e-06 0.54722
253 3RE4 TO1 7.88e-05 0.54508
254 3PDT ADP 4.395e-05 0.54485
255 2PUL ACP 3.89e-05 0.5413
256 2PUL ACP 3.89e-05 0.5413
257 2JLD AG1 1.967e-06 0.54039
258 2YEX YEX 1.192e-07 0.53976
259 2JLD AG1 9.564e-07 0.53892
260 3LKM AMP 2.524e-05 0.53859
261 1ZY5 ANP 4.892e-05 0.53648
262 4WHZ 3NL 2.245e-07 0.53635
263 1ZP9 ATP 6.567e-05 0.53623
264 2QCS ANP 5.591e-06 0.53619
265 4RLL E91 0.0002609 0.53274
266 3Q60 ATP 5.993e-05 0.53221
267 3FHI ANP 7.01e-06 0.53211
268 2X4Z X4Z 8.371e-08 0.53171
269 1ZP9 ATP 8.502e-05 0.53068
270 1ZP9 ATP 7.252e-05 0.5282
271 1ZP9 ATP 7.401e-05 0.52777
272 4LRJ ANP 7.467e-05 0.52759
273 4ORK GDP 0.0001566 0.52342
274 3BQC EMO 3.61e-05 0.52091
275 3SAO DBH 0.0006865 0.5201
276 4CYI ATP 6.921e-05 0.51823
277 1CM8 ANP 0.0001217 0.51732
278 1CM8 ANP 0.0001231 0.51708
279 4CYI ATP 8.008e-05 0.51528
280 4GYI ADP 0.0002296 0.51502
281 3AT4 CCK 4.158e-05 0.51333
282 4CYI ATP 7.206e-05 0.51234
283 4ORK GDP 0.0002065 0.51162
284 4ITH RCM 0.0001851 0.50849
285 2OXY K17 0.0002855 0.50835
286 3I0O ADP 0.0004135 0.50782
287 3I0O ADP 0.0004135 0.50782
288 2OXY K17 0.0003274 0.50661
289 3E8N VRA 4.353e-07 0.50509
290 3E8N VRA 4.353e-07 0.50509
291 3E8N ATP 4.353e-07 0.50509
292 3E8N ATP 4.353e-07 0.50509
293 2JDR L20 6.698e-06 0.50417
294 2JDR GLY ARG PRO ARG THR THR SER PHE ALA GLU 6.698e-06 0.50417
295 4ITH RCM 0.0002334 0.50363
296 2PYW ADP 0.0001249 0.50145
297 2IF8 ADP 0.0009595 0.50057
298 3TDV GDP 0.0002211 0.49965
299 3TDV GDP 0.0002399 0.49796
300 4CYI ATP 0.0001204 0.49752
301 4ORK GDP 0.0003163 0.49723
302 4BKY 82B 9.982e-09 0.49604
303 3MVH WFE 1.172e-05 0.49054
304 1W2D ADP 0.0009681 0.48871
305 1W2D ADP 0.001023 0.48746
306 4L3L 5FI 6.117e-07 0.487
307 1TZD ADP 0.001405 0.48419
308 4U44 3D9 6.062e-09 0.48316
309 4U44 3D9 6.062e-09 0.48316
310 4Q5H ANP 0.0005166 0.48216
311 3TZM 085 5.126e-08 0.48194
312 4ORK GDP 0.0005407 0.48123
313 2XMY CDK 2.382e-07 0.48119
314 2G30 ALA ALA PHE 0.005902 0.47584
315 4K55 H6P 0.003981 0.47487
316 2GU8 796 2.298e-07 0.47372
317 1GSA ADP 0.0003323 0.4737
318 1GSA ADP 0.0003323 0.4737
319 4AVB CMP 0.001568 0.47282
320 3KMW ATP 0.001022 0.47257
321 1RE8 BD2 2.702e-05 0.46984
322 1IA9 ANP 0.0007974 0.46888
323 2ET1 GLV 0.004285 0.46751
324 2BPM 529 1.182e-06 0.46588
325 3VBQ 0F5 4.349e-05 0.4638
326 4AVB CMP 0.0027 0.46087
327 1TQP ATP 0.0005713 0.45962
328 3VPB ADP 0.0004931 0.45874
329 4UAL 3FV 1.072e-07 0.4582
330 1AUX AGS 0.00176 0.4569
331 4AZT LY2 0.004153 0.45595
332 4OCV ANP 0.001535 0.45566
333 2ZL7 FUC GAL NGA 0.00687 0.45505
334 2YRX AMP 0.006807 0.45487
335 1TZD ADP 0.004042 0.45477
336 2BPM 529 1.67e-06 0.4545
337 3VPC ADP 0.001105 0.45446
338 4BCM T7Z 5.715e-08 0.45256
339 3RWP ABQ 1.02e-09 0.45162
340 3RWP ABQ 1.02e-09 0.45162
341 1UNH IXM 2.949e-08 0.44885
342 1PME SB2 4.81e-06 0.44848
343 4IJP 1EH 6.184e-07 0.44712
344 3SG8 TOY 0.0004605 0.44661
345 3SG8 TOY 0.0004605 0.44661
346 3WVR AMP 0.004365 0.44604
347 3BRN SRO 0.01027 0.44538
348 4NM5 ADP 1.681e-06 0.44474
349 4NM5 ADP 1.681e-06 0.44474
350 1I1E DM2 0.01021 0.44469
351 4I5C C5I 4.141e-07 0.44388
352 4IJP 1EH 7.922e-07 0.44388
353 4I5C C5I 4.598e-07 0.44362
354 4J24 EST 0.006064 0.44306
355 4J24 EST 0.006295 0.44224
356 2CFM AMP 0.007666 0.44214
357 1XDN ATP 0.005238 0.44211
358 4J24 EST 0.006429 0.44178
359 3ZPG 5GP 0.008025 0.44088
360 3O0G 3O0 1.669e-07 0.44085
361 3WVR AMP 0.005572 0.44078
362 3WVR AMP 0.005572 0.44078
363 4BBF O19 4.327e-07 0.44044
364 2B9H ADP 8.302e-07 0.43919
365 3TY5 ATP 0.008847 0.4389
366 4DFU QUE 0.01107 0.43815
367 4J26 EST 0.007772 0.4376
368 4J26 EST 0.007775 0.43759
369 3WVR AMP 0.0065 0.43746
370 3WVR AMP 0.0065 0.43746
371 2F9W PAU 0.01165 0.43697
372 4J24 EST 0.008121 0.43663
373 4QPM ADP 1.25e-06 0.43582
374 2VPQ ANP 0.002625 0.43428
375 1B4N GUA 0.01742 0.43414
376 3A8W ATP 4.108e-07 0.43406
377 1PHK ATP 1.181e-06 0.43406
378 1VHZ APR 0.01565 0.43403
379 1UNH IXM 4.043e-08 0.43392
380 3A8W ATP 4.029e-07 0.43371
381 3A8W ATP 4.029e-07 0.43371
382 3ORQ ADP 0.003903 0.43328
383 1OJ4 CDM 0.006862 0.43246
384 3JQ3 ADP 0.01249 0.43112
385 3JQ3 ADP 0.01249 0.43112
386 4AZW ATP 0.00442 0.43081
387 4JPS 1LT 0.007451 0.43073
388 3F8C HT1 0.02028 0.43064
389 2YAB AMP 1.505e-06 0.43059
390 4O1P ANP 6.952e-07 0.43025
391 3T4L ZEA 0.006698 0.42933
392 4O1P ANP 5.008e-07 0.42795
393 2VQD AP2 0.005181 0.42766
394 4MRP GSH 0.02174 0.42754
395 1BHX ASP PHE GLU GLU ILE 0.01464 0.42752
396 1Y8O ADP 0.01484 0.42721
397 4CYZ SIA GAL NAG 0.01832 0.42648
398 1YYE 196 0.01091 0.42629
399 3VPD ANP 0.004712 0.42626
400 4BBF O19 8.336e-07 0.42596
401 1K3A ACP 2.466e-07 0.4259
402 1Z6K OAA 0.02599 0.42543
403 4DFU QUE 0.02348 0.42487
404 4NST ADP 2.755e-06 0.42483
405 3CM2 X23 0.02421 0.42467
406 4ANW O92 0.001198 0.42465
407 3S6X SIA GAL BGC 0.02722 0.42453
408 4BBE 3O4 2.083e-08 0.424
409 3ETH ATP 0.005314 0.42391
410 2GC0 PAN 0.008785 0.42372
411 3N7S 3N7 0.02355 0.42279
412 3CM2 X23 0.02964 0.42277
413 4CYZ SIA GAL 0.02158 0.42267
414 1QKQ MAN 0.001249 0.42248
415 4ME6 ADP 0.02625 0.42189
416 4URG C2E 0.02733 0.42177
417 1PK8 ATP 0.003694 0.42167
418 4BKS X6C 0.02721 0.42138
419 3FIU AMP 0.01931 0.42124
420 2PNZ 5GP 0.04195 0.42102
421 3TY5 ADP 0.01396 0.42096
422 4NST ADP 3.65e-06 0.42089
423 1OJJ BGC GAL 0.0269 0.42078
424 1YRX FMN 0.01224 0.42023
425 4BBF O19 7.118e-07 0.42021
426 2ZMF CMP 0.008956 0.41998
427 1I7L ATP 0.00474 0.41997
428 1I7L ATP 0.00474 0.41997
429 4QPM ADP 3.688e-06 0.41988
430 3F81 STT 0.02292 0.41976
431 3NB0 G6P 0.02457 0.41965
432 4BKS X6C 0.03031 0.41957
433 4BKS X6C 0.02931 0.41956
434 3DGY 2GP 0.03192 0.41939
435 2IO8 ADP 0.004929 0.41924
436 2GQS ADP 0.01288 0.41917
437 3N1S 5GP 0.01521 0.4191
438 4BKS X6C 0.03129 0.41871
439 3CM2 X23 0.03529 0.4186
440 4BBF O19 8.534e-07 0.41838
441 3OPT AKG 0.032 0.41822
442 3FIU AMP 0.02241 0.41787
443 3B99 U51 0.01913 0.41769
444 1ZX5 LFR 0.0265 0.41725
445 1NY5 ADP 0.01202 0.41723
446 4BG4 ADP 0.01029 0.41716
447 2VD9 IN5 0.01433 0.41691
448 4W9F 3JU 0.03299 0.41674
449 3THR C2F 0.01478 0.41625
450 5FIV 3TL 0.01765 0.41588
451 3SG8 TOY 0.002809 0.41551
452 1XXR MAN 0.03657 0.41543
453 3CM2 X23 0.03742 0.41514
454 1PZL MYR 0.01342 0.41495
455 3S6X SIA GAL BGC 0.02559 0.41485
456 4LFI GNP 5.756e-06 0.41478
457 3G4Q MCH 0.02185 0.41474
458 2W58 ADP 0.04302 0.41462
459 2PEH LYS ARG LYS SER ARG TRP ASP GLU THR PRO 0.02599 0.4145
460 3CM2 X23 0.03985 0.41407
461 1QB7 ADE 0.02651 0.41404
462 3KP6 SAL 0.02181 0.41402
463 4PU5 ANP 0.007683 0.41376
464 4M69 ANP 1.492e-05 0.41372
465 3SLS 77D 0.01425 0.4137
466 4UWH JXM 0.01964 0.41356
467 3PHZ NAG GAL SIA 0.0319 0.41356
468 1U6R IOM 0.02366 0.41352
469 3CXO 1N5 0.02713 0.41351
470 3CXO 1N5 0.02713 0.41351
471 4AXD ANP 0.001119 0.41329
472 4O2B ACP 0.0125 0.41321
473 3BRN SRO 0.04278 0.4127
474 3FC2 IBI 1.646e-07 0.41265
475 4BBE 3O4 5.679e-08 0.4126
476 1EHI ADP 0.01291 0.41256
477 3OLL EST 0.0177 0.41242
478 4MGD 27N 0.02106 0.41205
479 4MG8 27J 0.02127 0.41184
480 1H4W BEN 0.04418 0.41173
481 3DOO SKM 0.04403 0.41168
482 3ZJX BOG 0.04123 0.41152
483 1T7R DHT 0.01849 0.41149
484 1YRX FMN 0.02166 0.41144
485 1T73 DHT 0.01591 0.41142
486 3OLL EST 0.01861 0.41136
487 3OLL EST 0.01861 0.41136
488 1T5Z DHT 0.01887 0.41106
489 3BPX SAL 0.04448 0.41089
490 1U6R ADP 0.01652 0.41064
491 1T74 DHT 0.01657 0.41058
492 4BTK DTQ 1.089e-05 0.41057
493 3CXW 7CP 4.085e-06 0.41051
494 1T76 DHT 0.01664 0.41048
495 4FE2 ADP 0.02648 0.41047
496 3CM2 X23 0.04526 0.41032
497 3CM2 X23 0.04526 0.41032
498 2CBO TH2 0.04422 0.41031
499 4CCW VKC 0.02492 0.41026
500 4KYS VIB 0.04351 0.41008
501 3RY9 1CA 0.01714 0.40987
502 3N1S 5GP 0.0272 0.40987
503 3I7V ATP 0.02973 0.40983
504 4E5W 0NT 7.768e-06 0.40971
505 2BE2 R22 0.0276 0.40955
506 2HK9 SKM 0.04469 0.40953
507 2BYC FMN 0.0237 0.40949
508 4W9H 3JF 0.03804 0.40943
509 1OUK 084 1.462e-08 0.40908
510 1RGE 2GP 0.04889 0.40887
511 1E4E ADP 0.0156 0.40871
512 4KYS VIB 0.04676 0.40834
513 1UO4 PIH 0.03873 0.40785
514 3DLS ADP 2.859e-06 0.4078
515 4B9K TG0 0.04113 0.4076
516 3KYF 5GP 5GP 0.03662 0.40667
517 2WW2 SWA 0.0415 0.40657
518 2AQX ATP 0.01301 0.40646
519 3W0O ADP 0.005488 0.40644
520 2QHV OC9 0.04341 0.40633
521 4B9K TG0 0.04345 0.40631
522 4AG9 16G 0.03722 0.40629
523 2IDO TMP 0.04651 0.40601
524 4B1L FRU 0.04617 0.406
525 3RY9 1CA 0.02065 0.40599
526 2PR5 FMN 0.0181 0.40568
527 2PR5 FMN 0.0181 0.40568
528 4MG7 27H 0.02127 0.40538
529 4OUC 5ID 5.153e-06 0.40519
530 4FVQ ATP 2.698e-05 0.405
531 3UUA 0CZ 0.02934 0.40484
532 3UUA 0CZ 0.02934 0.40484
533 1RV0 DAN 0.02543 0.40473
534 2I4O ATP 0.03991 0.4047
535 1XI9 PLP 0.04673 0.40459
536 4LI4 AMP 0.0471 0.40441
537 4B9K TG0 0.04727 0.40432
538 1T79 DHT 0.02259 0.40413
539 1UYY BGC BGC BGC 0.03523 0.4041
540 4INI AMP 0.03174 0.40312
541 1UO5 PIH 0.0436 0.40306
542 3DLS ADP 3.097e-06 0.4028
543 2Z49 AMG 0.04963 0.40279
544 3DLS ADP 4.946e-06 0.40275
545 3DLS ADP 4.946e-06 0.40275
546 3B6R CRN 0.01419 0.40273
547 2HKA C3S 0.02098 0.40267
548 4HT2 V50 0.02846 0.40233
549 2AWN ADP 0.04572 0.4023
550 3NCQ ATP 0.01625 0.4021
551 3NCQ ATP 0.01625 0.4021
552 3DLS ADP 3.607e-06 0.40203
553 3PTG 932 8.252e-07 0.40202
554 3DLS ADP 5.5e-06 0.40181
555 3TPV ADE 0.02192 0.40178
556 3B6R ADP 0.02953 0.40154
557 4HT2 V50 0.02591 0.40127
558 1I9Z 2IP 0.03068 0.40116
559 1T7M DHT 0.02267 0.4011
560 4EJN 0R4 0.02282 0.40096
561 3W0O HY0 0.006571 0.40087
562 3L3Z DHT 0.02294 0.40085
563 3N1S 5GP 0.04087 0.40077
564 3L3X DHT 0.02305 0.40075
565 3BF1 PAU 0.04118 0.4006
566 4W9H 3JF 0.04809 0.40041
567 2GVJ DGB 0.02046 0.40032
568 4K3H 1OM 0.0207 0.40009
569 3KJS NAP 0.006896 0.40003
Pocket No.: 2; Query (leader) PDB : 4F65; Ligand: 0S9; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 4f65.bio1) has 29 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc)
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