Receptor
PDB id Resolution Class Description Source Keywords
1AWI 2.2 Å NON-ENZYME: MOBILE HUMAN PLATELET PROFILIN COMPLEXED WITH THE L-PRO10 PEPTIDE HOMO SAPIENS PROFILIN POLY-L-PROLINE ACTIN CYTOSKELETON COMPLEX (ACTIN-BINDING PROTEIN/PEPTIDE)
Ref.: STRUCTURE OF THE PROFILIN-POLY-L-PROLINE COMPLEX INVOLVED IN MORPHOGENESIS AND CYTOSKELETAL REGULATION. NAT.STRUCT.BIOL. V. 4 953 1997
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
PRO PRO PRO PRO PRO PRO PRO PRO PRO PRO P:1;
Valid;
none;
Kd = 90 uM
989.185 n/a O=C([...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1AWI 2.2 Å NON-ENZYME: MOBILE HUMAN PLATELET PROFILIN COMPLEXED WITH THE L-PRO10 PEPTIDE HOMO SAPIENS PROFILIN POLY-L-PROLINE ACTIN CYTOSKELETON COMPLEX (ACTIN-BINDING PROTEIN/PEPTIDE)
Ref.: STRUCTURE OF THE PROFILIN-POLY-L-PROLINE COMPLEX INVOLVED IN MORPHOGENESIS AND CYTOSKELETAL REGULATION. NAT.STRUCT.BIOL. V. 4 953 1997
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 68 families.
1 1AWI Kd = 90 uM PRO PRO PRO PRO PRO PRO PRO PRO PRO PRO n/a n/a
2 1CF0 - PRO PRO PRO PRO PRO PRO PRO PRO IYR n/a n/a
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 59 families.
1 1AWI Kd = 90 uM PRO PRO PRO PRO PRO PRO PRO PRO PRO PRO n/a n/a
2 1CF0 - PRO PRO PRO PRO PRO PRO PRO PRO IYR n/a n/a
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 40 families.
1 1AWI Kd = 90 uM PRO PRO PRO PRO PRO PRO PRO PRO PRO PRO n/a n/a
2 1CF0 - PRO PRO PRO PRO PRO PRO PRO PRO IYR n/a n/a
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: PRO PRO PRO PRO PRO PRO PRO PRO PRO PRO; Similar ligands found: 14
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1AWI; Ligand: PRO PRO PRO PRO PRO PRO PRO PRO PRO PRO; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 1awi.bio1) has 18 residues
No: Leader PDB Ligand Sequence Similarity
APoc FAQ
Feedback