Receptor
PDB id Resolution Class Description Source Keywords
1AZS 2.3 Å EC: 4.6.1.1 COMPLEX OF GS-ALPHA WITH THE CATALYTIC DOMAINS OF MAMMALIAN ADENYLYL CYCLASE CANIS LUPUS FAMILIARIS COMPLEX (LYASE/HYDROLASE) HYDROLASE SIGNAL TRANSDUCING PROTEIN CYCLASE EFFECTOR ENZYME
Ref.: CRYSTAL STRUCTURE OF THE CATALYTIC DOMAINS OF ADENYLYL CYCLASE IN A COMPLEX WITH GSALPHA.GTPGAMMAS. SCIENCE V. 278 1907 1997
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
FKP A:1;
Valid;
none;
submit data
550.727 C30 H50 N2 O7 CC1(C...
GSP C:404;
Valid;
none;
submit data
539.246 C10 H16 N5 O13 P3 S c1nc2...
MG C:403;
Part of Protein;
none;
submit data
24.305 Mg [Mg+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1CS4 2.5 Å EC: 4.6.1.1 COMPLEX OF GS-ALPHA WITH THE CATALYTIC DOMAINS OF MAMMALIAN ADENYLYL CYCLASE: COMPLEX WITH 2'-DEOXY-ADENOSINE 3'- M ONOPHOSPHATE, PYROPHOSPHATE AND MG CANIS LUPUS FAMILIARIS COMPLEX (LYASE/HYDROLASE) HYDROLASE SIGNAL TRANSDUCING PROTEIN CYCLASE EFFECTOR ENZYME LYASE/HYDROLASE COMPLEXLYASE/LYASE/SIGNALING PROTEIN COMPLEX
Ref.: MOLECULAR BASIS FOR P-SITE INHIBITION OF ADENYLYL CYCLASE. BIOCHEMISTRY V. 39 14464 2000
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 8 families.
1 1CS4 ic50 = 2.7 uM 101 C10 H14 N5 O6 P c1nc(c2c(n....
2 1AZS - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
3 1CUL - 3PO H5 O10 P3 OP(=O)(O)O....
70% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 8 families.
1 1CS4 ic50 = 2.7 uM 101 C10 H14 N5 O6 P c1nc(c2c(n....
2 1AZS - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
3 1CUL - 3PO H5 O10 P3 OP(=O)(O)O....
50% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 8 families.
1 1CS4 ic50 = 2.7 uM 101 C10 H14 N5 O6 P c1nc(c2c(n....
2 1AZS - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
3 1CUL - 3PO H5 O10 P3 OP(=O)(O)O....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: FKP; Similar ligands found: 2
No: Ligand ECFP6 Tc MDL keys Tc
1 FKP 1 1
2 FOK 0.635417 0.677419
Ligand no: 2; Ligand: GSP; Similar ligands found: 120
No: Ligand ECFP6 Tc MDL keys Tc
1 GSP 1 1
2 GP3 0.897436 0.925
3 GTP 0.853659 0.948718
4 GNH 0.829268 0.936709
5 GDP 0.817073 0.948718
6 G1R 0.8 0.936709
7 GCP 0.77907 0.925
8 GNP 0.770115 0.925
9 GMV 0.767442 0.925
10 G 0.756098 0.935897
11 5GP 0.756098 0.935897
12 G2R 0.747253 0.91358
13 GDD 0.744681 0.91358
14 GKE 0.744681 0.91358
15 GDC 0.744681 0.91358
16 GPG 0.73913 0.91358
17 GTG 0.736842 0.891566
18 G3A 0.729167 0.925
19 G5P 0.721649 0.925
20 GFB 0.71875 0.91358
21 GDR 0.71875 0.91358
22 GAV 0.714286 0.987179
23 GP2 0.712644 0.91358
24 Y9Z 0.708333 0.860465
25 JB2 0.69697 0.91358
26 GKD 0.69697 0.91358
27 GDP MG 0.696629 0.878049
28 G2P 0.692308 0.91358
29 GPD 0.69 0.880952
30 GDX 0.69 0.925
31 GCP G 0.677419 0.888889
32 ALF 5GP 0.67033 0.847059
33 0O2 0.666667 0.935897
34 GTP MG 0.666667 0.878049
35 BEF GDP 0.666667 0.847059
36 YGP 0.663265 0.858824
37 JB3 0.657143 0.902439
38 GDP AF3 0.645833 0.847059
39 GDP ALF 0.645833 0.847059
40 GMP 0.641975 0.835443
41 G3D 0.638298 0.935897
42 NGD 0.635514 0.91358
43 2MD 0.633027 0.894118
44 CAG 0.630631 0.840909
45 G4P 0.625 0.935897
46 FEG 0.62037 0.83908
47 U2G 0.62037 0.891566
48 G G 0.617647 0.901235
49 MGD 0.616071 0.894118
50 CG2 0.609091 0.891566
51 TPG 0.598291 0.804348
52 3GP 0.595506 0.898734
53 GDP 7MG 0.590476 0.86747
54 MD1 0.581197 0.894118
55 PGD 0.581197 0.926829
56 2GP 0.577778 0.911392
57 DGT 0.561224 0.878049
58 DBG 0.558333 0.902439
59 G1G 0.550847 0.880952
60 SAP 0.547368 0.924051
61 AGS 0.547368 0.924051
62 FE9 0.546219 0.8
63 G4M 0.539062 0.840909
64 G A A A 0.529915 0.878049
65 MGP 0.525253 0.91358
66 GPX 0.524272 0.898734
67 BGO 0.521739 0.879518
68 DGI 0.520408 0.878049
69 I2C FE2 CMO CMO 0.516667 0.774194
70 IDP 0.515464 0.923077
71 GGM 0.508475 0.858824
72 G1R G1R 0.508065 0.879518
73 PGD O 0.504 0.875
74 G G U 0.5 0.888889
75 GTA 0.486726 0.891566
76 P2G 0.484536 0.839506
77 GPC 0.483607 0.83908
78 G C 0.483333 0.857143
79 P1G 0.474747 0.829268
80 DGP 0.474227 0.865854
81 DG 0.474227 0.865854
82 BA3 0.46875 0.85
83 IMP 0.463918 0.910256
84 B4P 0.463918 0.85
85 AP5 0.463918 0.85
86 G2Q 0.462963 0.91358
87 G G G RPC 0.459016 0.833333
88 U G A 0.452555 0.847059
89 ATP 0.45 0.873418
90 G G G C 0.448819 0.869048
91 A2D 0.447917 0.85
92 AQP 0.445545 0.873418
93 5FA 0.445545 0.873418
94 G7M 0.444444 0.901235
95 G U34 0.442623 0.847059
96 01G 0.442478 0.860465
97 ITT 0.44 0.825
98 SGP 0.44 0.876543
99 G C C C 0.431818 0.879518
100 DG DG 0.428571 0.825581
101 A4P 0.42623 0.829545
102 PCG 0.423077 0.886076
103 35G 0.423077 0.886076
104 C2E 0.423077 0.875
105 MGO 0.420561 0.823529
106 ADP 0.42 0.873418
107 ANP 0.419048 0.851852
108 5GP 5GP 0.419048 0.839506
109 ADQ 0.418182 0.829268
110 APR 0.417476 0.85
111 AR6 0.417476 0.85
112 AD9 0.413462 0.851852
113 UP5 0.413223 0.831325
114 A22 0.412844 0.8625
115 25L 0.412281 0.8625
116 M33 0.411765 0.839506
117 JBT 0.410405 0.783505
118 ACP 0.407767 0.851852
119 ACQ 0.40566 0.851852
120 A1R 0.405405 0.8
Similar Binding Sites
Pocket no: 1; Query (leader) PDB : 1CS4; Ligand: 101; Similar sites found: 24
This union binding pocket (no: 1) in the query (biounit: 1cs4.bio1) has 34 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc)
1 1CS4 101 1.443e-19 1
2 2BW7 APC 4.331e-07 0.56391
3 4OYB 1VJ 0.001103 0.4441
4 2QV6 GTP 0.0003438 0.38795
5 1YBU APC 0.001478 0.34966
6 2PK3 GDD 0.043 0.32964
7 3WBZ ATP 0.005294 0.32508
8 1YYE 196 0.02021 0.3227
9 3UJS 0V5 0.02021 0.31928
10 3OLL EST 0.02109 0.31674
11 4MG8 27J 0.03517 0.31188
12 4G9Z G 0.03699 0.30208
13 3EVG SAH 0.04777 0.29978
14 2PZI AXX 0.04058 0.29294
15 4NV0 MG7 0.04414 0.28725
16 2C63 ILE 0.03503 0.2848
17 4ARE FLC 0.03263 0.28147
18 1HBK COA 0.01738 0.2812
19 4WH9 3M8 0.007185 0.28018
20 2HBL AMP 0.03897 0.27495
21 1L5Y BEF 0.04652 0.26988
22 3WAR NIO 0.03437 0.26913
23 1ICV NIO 0.007699 0.26693
24 3SXU ASP 0.02666 0.26163
Pocket no: 2; Query (leader) PDB : 1CS4; Ligand: GSP; Similar sites found: 543
This union binding pocket (no: 2) in the query (biounit: 1cs4.bio1) has 23 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc)
1 1CS4 GSP 4.228e-17 1
2 1AZT GSP 1.895e-16 0.97771
3 1TAD ALF 3.109e-15 0.94784
4 1TAD ALF 3.331e-15 0.9467
5 1SVK ALF 4.774e-15 0.93957
6 1BH2 GSP 3.331e-15 0.93838
7 3CX8 GSP 5.218e-15 0.92999
8 2XTZ GSP 3.22e-15 0.92035
9 2ODE ALF 1.632e-14 0.9125
10 1GOT GDP 1.349e-13 0.83456
11 1Y3A GDP 6.292e-13 0.82357
12 1ZCB GDP 3.63e-14 0.82053
13 1FQJ GDP 2.474e-13 0.8057
14 1GP2 GDP 7.508e-13 0.80464
15 1FQK GDP 4.742e-13 0.79512
16 4KAX GTP 1.961e-12 0.77023
17 2A5F GTP 2.199e-12 0.76837
18 1O3Y GTP 1.674e-11 0.76332
19 2W83 GTP 3.341e-12 0.76153
20 3DOE GTP 4.911e-12 0.75553
21 2OM2 GDP 5.07e-12 0.75507
22 3BH7 ALF 7.315e-11 0.75062
23 3PCR GTP 3.451e-11 0.75004
24 4M9Q GNP 1.06e-11 0.74253
25 4BAS GNP 3.773e-12 0.74182
26 3AB3 GDP 1.561e-12 0.7375
27 4GOJ GNP 1.526e-11 0.73676
28 3T12 GDP 1.52e-11 0.73524
29 3WYG GTP 1.449e-10 0.73448
30 2J59 GTP 6.259e-12 0.73443
31 2C77 GNP 2.003e-11 0.73159
32 1KSH GDP 2.454e-11 0.72914
33 4HAT GNP 2.862e-10 0.725
34 2Y8E GNP 2.404e-10 0.71809
35 1IBR GNP 3.935e-10 0.71581
36 3WYF GTP 4.061e-10 0.71522
37 3M1I GTP 5.055e-10 0.71432
38 2C78 GNP 7.048e-11 0.70996
39 1VG8 GNP 4.053e-10 0.70844
40 2QTV GNP 3.631e-10 0.70682
41 2FFQ GSP 8.891e-10 0.70672
42 1J2J GTP 4.1e-11 0.70517
43 3VMF GTP 6.344e-10 0.70016
44 1NVU GTP 9.154e-10 0.70003
45 2GJ8 ALF 9.924e-10 0.69853
46 1YZQ GNP 8.693e-10 0.69774
47 1UPT GTP 6.799e-11 0.69545
48 1ZC3 GNP 1.503e-09 0.69385
49 1R4A GNP 1.995e-10 0.69274
50 1WA5 GTP 2.177e-09 0.69264
51 3RAB GNP 1.258e-09 0.69087
52 1M2O GNP 8.863e-10 0.69044
53 1R2Q GNP 1.54e-09 0.69032
54 1NVV GNP 1.661e-09 0.68891
55 1YZK GNP 1.244e-09 0.68772
56 1GUA GNP 1.603e-09 0.68637
57 4NCN GTP 1.134e-09 0.68591
58 2D7C GTP 1.376e-09 0.68586
59 4HDO GNP 1.691e-09 0.68538
60 1Z08 GNP 2.109e-09 0.68444
61 1OIX GDP 1.818e-09 0.68403
62 1LFD GNP 1.267e-09 0.68388
63 3T1O GDP 1.715e-11 0.68337
64 4TMZ GSP 1.581e-09 0.68329
65 2FH5 GTP 7.395e-10 0.68207
66 2UZI GTP 2.767e-09 0.67937
67 2BME GNP 1.689e-09 0.67859
68 4C4P GNP 2.688e-09 0.67677
69 3BC1 GNP 2.739e-09 0.67642
70 1Z06 GNP 1.106e-09 0.67577
71 3TNF GNP 3.019e-09 0.67461
72 3GJX GTP 3.265e-09 0.67315
73 3MJH GTP 2.758e-09 0.67301
74 2CL6 CAG 5.797e-09 0.67133
75 4LX0 BEF 3.024e-09 0.67131
76 3QBT GNP 2.54e-09 0.67111
77 1NRJ GTP 7.156e-10 0.67084
78 3TKL GTP 3.118e-09 0.67075
79 4HDQ GNP 4.523e-09 0.67019
80 2BVN GNP 7.162e-11 0.66895
81 2C5L GTP 3.792e-09 0.66713
82 1Z0K GTP 3.929e-09 0.66647
83 1ZJ6 G3D 5.797e-12 0.66475
84 1YZG GDP 5.792e-12 0.66452
85 3NKV GNP 6.246e-09 0.66416
86 3WXM GTP 2.147e-09 0.66288
87 1S8F GDP 6.79e-09 0.6626
88 3N5C GDP 2.166e-11 0.66252
89 1ZD9 GDP 6.013e-10 0.65973
90 1KAO GDP 8.164e-09 0.65915
91 1Z0J GTP 6.173e-09 0.65813
92 3AQ4 GDP 8.086e-12 0.65731
93 1RE0 GDP 8.494e-12 0.65667
94 1S9D GDP 8.529e-12 0.65662
95 1SKQ GDP 1.437e-11 0.65296
96 1WF3 GNP 3.908e-09 0.65213
97 4KVG GTP 7.41e-09 0.65144
98 1UAD GNP 8.896e-09 0.65138
99 4LHW GNP 1.402e-08 0.64608
100 1MH1 GNP 1.956e-08 0.64283
101 1PUJ GNP 3.28e-11 0.64233
102 2EW1 GNP 7.409e-09 0.64226
103 4DSU GDP 2.12e-08 0.64133
104 4V0K GDP 8.509e-10 0.63958
105 1YZN GNP 1.701e-08 0.6394
106 3WYA GDP 4.474e-11 0.63785
107 1F6B GDP 4.32e-10 0.63707
108 3RWO GDP 3.579e-08 0.63431
109 1KMQ GNP 1.171e-08 0.63415
110 1G7S GDP 7.232e-11 0.63229
111 1EK0 GNP 2.182e-08 0.63161
112 1Z2A GDP 2.27e-08 0.63088
113 4B47 GDP 7.306e-11 0.63076
114 3KUD GDP 8.01e-09 0.6301
115 4J0Q GDP 9.935e-11 0.6291
116 1KK1 GNP 1.329e-10 0.6277
117 1CLU DBG 1.207e-07 0.62759
118 1MR3 G3D 3.108e-10 0.62754
119 4P3Y GDP 1.248e-10 0.62754
120 1TU3 GNP 3.256e-08 0.62741
121 1U8Z GDP 3.35e-08 0.62688
122 1FZQ GDP 1.308e-10 0.62631
123 3WY9 GDP 1.217e-10 0.62609
124 1YVD GNP 3.053e-08 0.62545
125 3U6B GDP 1.554e-10 0.62504
126 2FJU GSP 1.256e-08 0.62478
127 1DAR GDP 1.578e-10 0.62378
128 4G5G GDP 4.752e-10 0.62377
129 1E96 GTP 4.102e-08 0.62314
130 1TX4 ALF 4.164e-08 0.62286
131 4K81 GTP 3.679e-08 0.62202
132 1D8T GDP 5.805e-10 0.62089
133 2HF9 GSP 6.939e-08 0.61918
134 3U6K GDP 8.6e-10 0.61659
135 2HCJ GDP 3.557e-10 0.6158
136 4NON GDP 7.261e-08 0.61552
137 2A9K GDP 1.012e-08 0.61527
138 1GWN GTP 1.178e-08 0.61493
139 2WKQ GTP 5.595e-08 0.61432
140 2WJH GDP 3.574e-10 0.61333
141 2X2E GDP 1.112e-07 0.61303
142 1X1R GDP 8.403e-08 0.6128
143 2W2X GSP 1.572e-08 0.61019
144 2G77 GDP 7.003e-09 0.60847
145 1XTQ GDP 7.773e-08 0.60828
146 3TH5 GNP 1.957e-08 0.60733
147 2F9L GDP 9.466e-08 0.60466
148 1CXZ GSP 2.318e-08 0.60374
149 3GJ8 GDP 2.45e-09 0.60335
150 3GJ5 GDP 2.848e-09 0.60152
151 1M7B GTP 2.759e-08 0.60124
152 1NF3 GNP 4.637e-08 0.60112
153 1VG1 GDP 2.474e-09 0.60108
154 1Z0A GDP 5.321e-09 0.60084
155 3GJ3 GDP 3.263e-09 0.59954
156 3GJ0 GDP 7.075e-09 0.59942
157 3Q85 GNP 1.087e-09 0.5985
158 2QN6 GDP 4.408e-10 0.5957
159 3GJ4 GDP 4.615e-09 0.59479
160 1D2E GDP 1.245e-09 0.59427
161 3GJ7 GDP 5.064e-09 0.59383
162 3SFV GDP 1.089e-07 0.59365
163 1MKY GDP 4.426e-10 0.59362
164 3Q72 GNP 1.392e-09 0.59271
165 2GCO GNP 4.379e-08 0.59152
166 1VG9 GDP 2.436e-08 0.58948
167 2A5J GDP 3.026e-08 0.58741
168 3CNL GNP 4.017e-10 0.58704
169 2HT6 GDP 5.492e-10 0.5867
170 4U5X GNP 5.578e-08 0.58606
171 3T5G GDP 1.567e-08 0.58581
172 1YRB GDP 3.607e-09 0.58539
173 4DKX GDP 7.291e-09 0.58371
174 2CJW GDP 3.498e-09 0.58211
175 1A2K GDP 3.937e-09 0.58147
176 4HI0 GDP 3.415e-08 0.5801
177 2ZEJ GDP 1.181e-08 0.57777
178 1VG0 GDP 2.809e-08 0.57765
179 3CPJ GDP 6.82e-08 0.57522
180 2BCG GDP 1.919e-07 0.57516
181 2WJG GDP 4.871e-10 0.5743
182 1RYH GNP 2.01e-08 0.5741
183 2EFE GNH 1.405e-07 0.5727
184 3EC1 GDP 9.241e-09 0.57091
185 1WDT GTP 3.838e-08 0.56889
186 1Z0F GDP 2.297e-08 0.56687
187 1TQ4 GDP 9.168e-08 0.56633
188 2RCN GDP 9.117e-09 0.56475
189 2X77 GDP 1.637e-08 0.56333
190 1WQ1 GDP 2.322e-07 0.56279
191 1KY3 GDP 7.888e-08 0.56224
192 1RJ9 GCP 1.362e-05 0.56026
193 2GCN GDP 8.728e-07 0.55669
194 1D5C GDP 1.95e-07 0.55628
195 3TK1 GDP 1.133e-08 0.55525
196 4DCT GDP 3.845e-06 0.5549
197 1G16 GDP 5.824e-07 0.55442
198 2NGR GDP 7.895e-08 0.5544
199 4D0N GDP 7.453e-08 0.54221
200 4LC1 GDP 1.385e-07 0.54082
201 3REF GDP 1.53e-06 0.53918
202 1JWY GDP 8.887e-08 0.53884
203 1A4R GDP 1.691e-06 0.53779
204 1GRN GDP 5.039e-07 0.53499
205 1A4R GNH 2.061e-06 0.53439
206 4DID GDP 2.476e-07 0.53425
207 4ITR GDP 5.031e-07 0.53313
208 2WJH FLC 6.891e-08 0.53277
209 1HE1 GDP 2.435e-06 0.53264
210 1DS6 GDP 3.175e-07 0.53135
211 1IWE IMP 8.112e-05 0.53121
212 2HV8 GTP 4.375e-05 0.53093
213 3LXR GDP 7.895e-07 0.52833
214 2WOJ ADP 1.079e-05 0.52488
215 2J0V GDP 6.368e-07 0.52091
216 4WZA ACP 7.208e-05 0.51971
217 3ZQ6 ADP 1.274e-05 0.5195
218 1SVI GDP 2.909e-07 0.51472
219 3E5H GNP 0.0001065 0.51071
220 3T34 GDP 4.322e-06 0.50981
221 2XTN GTP 1.368e-05 0.50737
222 1IHU ADP 0.0001278 0.50471
223 4H1V GNP 2.971e-06 0.50455
224 3ZFD ANP 9.676e-07 0.50187
225 3ZS9 ADP 3.783e-05 0.49929
226 3A1S GDP 1.45e-06 0.49922
227 1I4D GDP 1.361e-06 0.49482
228 2WIC GNP 0.0003012 0.49398
229 1G4U GDP 4.322e-06 0.49107
230 2C04 GCP 1.1e-05 0.48946
231 1G3Q ADP 2.518e-06 0.48886
232 2B8W ALF 2.53e-05 0.48824
233 1M7G AV2 0.0008138 0.48317
234 4LPS GDP 5.428e-07 0.48213
235 1FP6 ADP 4.017e-05 0.4792
236 3DDC GNP 0.0005675 0.47914
237 3E70 GDP 0.0001022 0.47866
238 1Y63 ADP 2.508e-06 0.47749
239 1OW3 GDP 9.534e-06 0.4764
240 4JLN 18V 0.0006251 0.47617
241 4E03 ADP 8.736e-06 0.4758
242 4OHY ANP 0.0003045 0.47432
243 1W0J ADP 0.0004072 0.47427
244 4IDN GNP 0.0001348 0.47354
245 1V8K ANP 3.834e-06 0.47309
246 2QEN ADP 1.31e-05 0.47103
247 2BEK ATP 0.0004213 0.47091
248 4KVA GTP 2.572e-05 0.46995
249 1F5N GNP 0.0001039 0.46991
250 1E4V AP5 0.0005587 0.46935
251 2IYL GDP 1.95e-05 0.46884
252 2OFW ADX 0.0004167 0.46827
253 2FNA ADP 0.0001722 0.46683
254 2PEZ DAT 0.0003589 0.46647
255 2GKS ADP 0.0003024 0.46631
256 2CK3 ANP 0.0005753 0.4662
257 4OI4 ATP 0.0001829 0.46572
258 1M7G ADP 0.0003736 0.46571
259 2V7Q ATP 0.0003413 0.46402
260 4BQS ADP 0.0003458 0.46378
261 1X6V ADP 0.001293 0.46345
262 1LVG ADP 1.084e-06 0.46329
263 1QF5 GDP 0.004651 0.46327
264 3PQC GDP 2.25e-05 0.46031
265 1G7C 5GP 2.769e-07 0.46014
266 3ZIA ATP 1.503e-05 0.4601
267 3FWY ADP 5.614e-05 0.45971
268 1SVM ATP 0.0002578 0.45942
269 2QG6 NMN 0.0003735 0.45867
270 1W0J ADP 0.000911 0.45849
271 1FQJ ALF 3.435e-07 0.45745
272 3ZIA ADP 1.7e-05 0.45705
273 2ZFI ADP 3.958e-05 0.457
274 3Q9L ATP 5.944e-05 0.4568
275 3DEF GDP 5.329e-05 0.45671
276 2Q2Y ADP 0.003262 0.45493
277 1YTM ATP 8.174e-05 0.45438
278 2VB6 ADP 0.0002395 0.45406
279 3W5J GDP 7.242e-09 0.45401
280 1FQK ALF 5.224e-07 0.45389
281 3DC4 ADP 3.563e-06 0.4537
282 3IIJ ADP 1.341e-05 0.45337
283 4P4T GDP 0.001403 0.45241
284 1LVK MNT 0.00173 0.45158
285 1ION ADP 3.065e-05 0.45145
286 1ZUI SKM 0.0007442 0.45097
287 3A4M ADP 2.503e-06 0.4504
288 1OS1 ATP 0.0007568 0.44899
289 3BOS CDP 1.048e-05 0.44729
290 2FAH GDP 0.00116 0.44411
291 1DAK ADP 0.006578 0.4441
292 1NJF AGS 0.0002023 0.44392
293 2YNM ADP 0.002548 0.44281
294 1JJV ATP 8.862e-06 0.44271
295 1AKY AP5 0.002335 0.44235
296 1KK8 BEF 0.0001384 0.44202
297 4MKF AP5 0.002172 0.44145
298 3VX3 ADP 0.0002005 0.44027
299 1HTW ADP 2.34e-05 0.43955
300 1NJF ADP 0.0002784 0.43901
301 1XKV ATP 5.501e-05 0.43895
302 2CK3 ADP 0.0008822 0.43883
303 1QF9 ADP 0.002094 0.43842
304 1BG2 ADP 8.061e-07 0.43821
305 4MKG AP5 0.002655 0.43751
306 3IO3 ADP 4.882e-05 0.43742
307 2ZR9 DTP 2.276e-05 0.43661
308 3KTA AP5 0.0006446 0.43596
309 2Y65 ADP 1.037e-06 0.43558
310 4QOS ADP 5.964e-05 0.43484
311 1L2T ATP 0.001232 0.43456
312 2IXE ATP 0.0002129 0.43379
313 3COB ADP 5.58e-06 0.43219
314 4TTQ ATP 2.089e-05 0.43097
315 2KIN ADP 1.521e-06 0.43096
316 4HSE ADP 0.0001636 0.43075
317 2BIF ANP 0.00167 0.43068
318 3FYH ADP 0.0001066 0.42979
319 1VHT BA3 0.0003902 0.4294
320 2RGX AP5 0.00356 0.42937
321 1KO8 6PG 0.0005203 0.42882
322 1W5T ANP 0.001062 0.42782
323 4IOK ADP 0.007193 0.42775
324 2BIF BOG 0.009332 0.4273
325 2ZPA ADP 0.0007613 0.42717
326 2XT3 ADP 7.75e-06 0.42706
327 1UKZ ADP 0.003405 0.42637
328 1Z83 AP5 0.003196 0.42621
329 4FRZ ADP 2.365e-06 0.42618
330 1SQ5 ADP 2.393e-05 0.42599
331 4CVN ADP 4.867e-05 0.42558
332 3H4S ADP 2.447e-06 0.42548
333 1R0X ATP 0.0005819 0.42528
334 4KFU ACP 0.001248 0.42498
335 4QM7 DC 0.002719 0.42483
336 1T5C ADP 3.017e-06 0.42481
337 3RLF ANP 0.001714 0.42462
338 4NU0 AP5 0.004854 0.42333
339 3CH5 GDP 0.01498 0.423
340 2V26 ADP 0.0006215 0.42274
341 2QZ4 ADP 0.0001102 0.4223
342 1W5T ADP 0.001476 0.42193
343 1GOJ ADP 4.148e-06 0.42179
344 2V7Q ADP 2.139e-05 0.42172
345 3LRE ADP 4.43e-06 0.4213
346 2GDJ ANP 0.0001213 0.42086
347 3B5J 12D 2.868e-05 0.42076
348 3EWA ANP 0.0001015 0.42041
349 1S3G AP5 0.005195 0.41953
350 1JI0 ATP 2.558e-05 0.41932
351 3QKT ANP 0.0001259 0.41847
352 2CHG ANP 0.0004891 0.4183
353 1FNN ADP 0.0009605 0.41817
354 1JWY ADP 0.0002099 0.41796
355 1JJ7 ADP 3.936e-06 0.41788
356 2VVG ADP 5.507e-06 0.4178
357 4BFW ZVW 0.01136 0.41762
358 1F2U ATP 0.00284 0.41722
359 2PZE ATP 3.73e-06 0.41703
360 1UJ2 C5P 0.01567 0.4166
361 2BBS ATP 4.055e-06 0.41642
362 1OXV ANP 1.178e-05 0.41639
363 2VF7 ADP 0.00535 0.41633
364 3FB4 AP5 0.006372 0.41558
365 4P32 ADP 0.001042 0.41469
366 3MD0 GDP 0.00504 0.41465
367 2JLR ANP 0.0001856 0.41436
368 1IN4 ADP 0.001202 0.41427
369 1H65 GDP 0.01078 0.41409
370 1G6H ADP 1.638e-06 0.41378
371 1XX6 ADP 4.547e-05 0.41188
372 2VF7 ADP 0.006744 0.41188
373 3P4X ADP 0.0001137 0.41133
374 3EZ2 ADP 0.004356 0.41106
375 1YQT ADP 0.004095 0.41044
376 1P72 ADP 0.004529 0.41033
377 1R6B ADP 0.009482 0.41026
378 3NHB ADP 2.219e-05 0.40986
379 3QF7 ANP 0.0006262 0.40923
380 3FKQ ATP 0.01015 0.40893
381 2ZTS ADP 0.01195 0.40795
382 3TMK T5A 0.009026 0.40758
383 2OZE AGS 0.01132 0.4068
384 1B7T ADP 0.0003043 0.40658
385 2XAU ADP 0.0002432 0.4059
386 1E2K TMC 0.01165 0.40508
387 4GBM A3P 0.003045 0.4046
388 4LJ9 ACP 0.0003857 0.4045
389 1NHX FTB 0.01524 0.4042
390 1F9V ADP 0.003795 0.40416
391 4AG5 ADP 1.828e-05 0.40309
392 3HU3 AGS 0.03785 0.40157
393 3KJI ADP 0.01491 0.4014
394 4FCW ADP 0.0008368 0.40113
395 3AB1 FAD 0.01645 0.40057
396 2PL3 ADP 0.0004056 0.40052
397 3FVQ ATP 0.001084 0.39935
398 3H86 AP5 0.0126 0.39856
399 4IEE AGS 0.0002919 0.39819
400 4GOX A3P 0.005865 0.39747
401 1Z6T ADP 0.001282 0.39741
402 2CE7 ADP 0.01642 0.39721
403 2WHX ADP 8.982e-06 0.39669
404 1NY5 ADP 0.001721 0.39657
405 1JG3 ADN 0.02352 0.39558
406 3QVV 3QV 0.02544 0.39501
407 2V1X ADP 0.0007295 0.39408
408 2CBZ ATP 7.097e-06 0.39399
409 2Z3Y F2N 0.02752 0.39343
410 2YOH WMJ 0.01662 0.39324
411 1G6O ADP 0.0333 0.39323
412 2ZE7 DST 0.01078 0.39251
413 2W58 ADP 1.238e-05 0.39213
414 2D7D ADP 0.002132 0.39202
415 4A4Z ANP 0.001795 0.3914
416 2Q4W FAD 0.02218 0.39134
417 3QXC ATP 0.0375 0.39081
418 1OJ4 ANP 0.004374 0.39042
419 2C42 PYR 0.01927 0.39039
420 2ZPT A3P 0.04331 0.39032
421 2Y5K YCU 0.01698 0.39012
422 1ZIN AP5 0.02385 0.38993
423 3A7R LAQ 0.02293 0.38952
424 1WQ1 AF3 1.801e-05 0.38868
425 1G3M A3P 0.02952 0.38797
426 2CDN ADP 0.02046 0.38793
427 1P9B GDP 0.03628 0.38789
428 3DZD ADP 0.002192 0.38712
429 4MUB OAQ 0.02601 0.38707
430 1HE1 AF3 3.358e-05 0.38598
431 4KP7 1UQ 0.04194 0.38497
432 1OE0 TTP 0.0217 0.38258
433 2PX8 SAH 0.01199 0.38174
434 1U0J ADP 0.00116 0.38161
435 2AWN ADP 7.022e-06 0.38126
436 2FNU PMP 0.0415 0.38016
437 1W4R TTP 0.02977 0.3794
438 2VVL FAD 0.04806 0.37932
439 2O4C NAD 0.03427 0.37801
440 3PP0 03Q 0.02298 0.37676
441 3FUU ADN 0.01957 0.37637
442 2O07 MTA 0.04283 0.37615
443 3AD8 NAD 0.04192 0.37537
444 3B7G ANP 0.001655 0.37449
445 4TMK T5A 0.04666 0.37447
446 2NGR AF3 0.0001215 0.37422
447 3LKZ SFG 0.0155 0.37421
448 3GCZ SAM 0.01213 0.37372
449 2GK6 ADP 0.001953 0.3733
450 1WY7 SAH 0.0236 0.37299
451 2GAG NAD 0.04457 0.37293
452 3RC3 ANP 0.003334 0.37263
453 4ITM ATP 0.03137 0.37258
454 4IXH IMP 0.0409 0.37195
455 2XOD FMN 0.02038 0.3719
456 3K8D CTP 0.04193 0.37148
457 1AQU A3P 0.01239 0.3708
458 2JAQ DCP 0.01981 0.36978
459 1NST A3P 0.01002 0.36959
460 3MGB PAP 0.01698 0.36943
461 1OFL ASG 0.04604 0.36829
462 2FSH ANP 0.004042 0.368
463 4IY7 0JO 0.03205 0.36733
464 1Q3Q ANP 0.04147 0.36732
465 3BFX A3P 0.02188 0.36725
466 4IYO 0JO 0.03312 0.36677
467 1OYY AGS 0.004891 0.36562
468 2GWH A3P 0.01892 0.36429
469 3IUY AMP 0.00676 0.36302
470 2D2F ADP 7.396e-05 0.36278
471 4CTK SAM 0.04871 0.36271
472 1RLJ FMN 0.0367 0.36184
473 2G77 AF3 0.0002008 0.36114
474 1OW3 MGF 8.686e-05 0.36069
475 1Q20 A3P 0.03008 0.36069
476 1BO4 COA 0.003984 0.36037
477 1I9G SAM 0.04823 0.36019
478 1G4U AF3 0.0001896 0.36004
479 3RK1 ATP 0.0209 0.35994
480 3DLS ADP 0.02044 0.35927
481 2IL4 COA 0.01555 0.35829
482 1S7N COA 0.03248 0.35771
483 3BD9 A3P 0.02749 0.35768
484 4PSW COA 0.008891 0.35717
485 2Q3R FMN 0.04068 0.35651
486 4O6M C5P 0.04111 0.35635
487 3F8K COA 0.04506 0.35567
488 2P41 SAH 0.03967 0.35561
489 3BXF 13P 0.04787 0.3553
490 1GRN AF3 0.0005482 0.35502
491 3G2O SAM 0.03872 0.354
492 1RDS GPC 0.04925 0.35319
493 2HS3 FGR 0.045 0.35302
494 3ZL8 ADP 0.03563 0.35264
495 1CM0 COA 0.0354 0.35066
496 4KBF AMP 0.01219 0.34962
497 4NSQ COA 0.0371 0.34939
498 2OG2 MLI 0.0001357 0.34936
499 2PHT MAN 0.03766 0.34899
500 2O0J ADP 0.01075 0.34878
501 3FJG 3PG 0.01199 0.34823
502 4QNW FMN 0.02608 0.34802
503 1QHH ATP 0.02709 0.34778
504 1Q2D COA 0.0316 0.34759
505 1GQY ACP 0.04529 0.34724
506 1QSN COA 0.04148 0.34712
507 2DPY ADP 0.0004728 0.3471
508 2WPW ACO 0.02541 0.34696
509 3B9Q MLI 0.0002124 0.3469
510 1P3D ANP 0.04709 0.34684
511 2WPX ACO 0.04896 0.34565
512 4CTC J99 0.03973 0.34429
513 1H5T TYD 0.02592 0.34396
514 1PUA COA 0.04134 0.3437
515 3BER AMP 0.02639 0.34316
516 3EW2 BTN 0.03075 0.34293
517 2B4D COA 0.04011 0.3428
518 2I4I AMP 0.0354 0.34166
519 2X7I CIT 0.0174 0.34107
520 3TBK ANP 0.01229 0.339
521 2OBM ADP 0.007314 0.33302
522 3KIH GDL 0.04659 0.33225
523 2ZJ5 ADP 0.005768 0.33044
524 3W6G FLC 0.02761 0.32798
525 3KIF GDL 0.03502 0.32564
526 3BY9 SIN 0.02892 0.32179
527 2V3U DSN 0.03799 0.321
528 2EXK XYS 0.04684 0.31843
529 2VOH CIT 0.00252 0.31617
530 2GJP MAL 0.009963 0.31427
531 3CV2 OXL 0.007074 0.31376
532 2ORZ LYS 0.04628 0.31357
533 2V2G BEZ 0.01325 0.31297
534 3VM7 GLC 0.009379 0.3125
535 4M6T SAM 0.03266 0.31153
536 2J5V PCA 0.007992 0.31034
537 3TTM PUT 0.03923 0.31027
538 3K8X B89 0.0302 0.31005
539 3R7F CP 0.04308 0.30965
540 1P7T PYR 0.04154 0.30508
541 1D8C GLV 0.03106 0.30209
542 2IX0 C5P 0.03491 0.29899
543 3FW3 GLC 0.0343 0.29015
Feedback