Receptor
PDB id Resolution Class Description Source Keywords
1AZT 2.3 Å EC: 4.-.-.- GS-ALPHA COMPLEXED WITH GTP-GAMMA-S BOS TAURUS HYDROLASE SIGNAL TRANSDUCING PROTEIN GTP-BINDING PROTEIN
Ref.: CRYSTAL STRUCTURE OF THE ADENYLYL CYCLASE ACTIVATOR SCIENCE V. 278 1943 1997
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GSP A:413;
B:411;
Valid;
Valid;
none;
none;
submit data
539.246 C10 H16 N5 O13 P3 S c1nc2...
MG A:403;
B:406;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
PO4 A:404;
A:405;
A:406;
A:407;
A:408;
A:409;
A:410;
A:411;
A:412;
B:403;
B:404;
B:405;
B:407;
B:408;
B:409;
B:410;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
94.971 O4 P [O-]P...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1AZT 2.3 Å EC: 4.-.-.- GS-ALPHA COMPLEXED WITH GTP-GAMMA-S BOS TAURUS HYDROLASE SIGNAL TRANSDUCING PROTEIN GTP-BINDING PROTEIN
Ref.: CRYSTAL STRUCTURE OF THE ADENYLYL CYCLASE ACTIVATOR SCIENCE V. 278 1943 1997
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 38 families.
1 1AZT - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 35 families.
1 1AZT - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
50% Homology Family (24)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 1GFI - ALF GDP n/a n/a
2 4N0E - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 4PAM - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
4 1AS0 - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
5 1GDD - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
6 4PAO - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
7 1BOF - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
8 4N0D - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
9 1SVS Kd = 2.3 nM GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
10 1SVK Kd = 1.1 nM ALF GDP n/a n/a
11 1GIL - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
12 3FFA Kd = 0.69 uM GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
13 1CIP - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
14 1GIA - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
15 1AS3 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
16 4PAN - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
17 4PAQ - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
18 1TAG - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
19 1TND - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
20 1TAD - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
21 1AZT - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
22 1BH2 - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
23 2XTZ - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
24 1ZCB - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GSP; Similar ligands found: 132
No: Ligand ECFP6 Tc MDL keys Tc
1 GSP 1 1
2 GP3 0.897436 0.925
3 GTP 0.853659 0.948718
4 GNH 0.829268 0.936709
5 GDP 0.817073 0.948718
6 G1R 0.8 0.936709
7 GCP 0.77907 0.925
8 GNP 0.770115 0.925
9 GMV 0.767442 0.925
10 5GP 0.756098 0.935897
11 G 0.756098 0.935897
12 G2R 0.747253 0.91358
13 GKE 0.744681 0.91358
14 GDD 0.744681 0.91358
15 GDC 0.744681 0.91358
16 GPG 0.73913 0.91358
17 GTG 0.736842 0.891566
18 G3A 0.729167 0.925
19 G5P 0.721649 0.925
20 GDR 0.71875 0.91358
21 GFB 0.71875 0.91358
22 GAV 0.714286 0.987179
23 GP2 0.712644 0.91358
24 6CK 0.71134 0.891566
25 Y9Z 0.708333 0.860465
26 JB2 0.69697 0.91358
27 GKD 0.69697 0.91358
28 GDP MG 0.696629 0.878049
29 G2P 0.692308 0.91358
30 GDX 0.69 0.925
31 GPD 0.69 0.880952
32 GDP BEF 0.688889 0.857143
33 GCP G 0.677419 0.888889
34 ALF 5GP 0.67033 0.847059
35 0O2 0.666667 0.935897
36 GTP MG 0.666667 0.878049
37 BEF GDP 0.666667 0.847059
38 YGP 0.663265 0.858824
39 JB3 0.657143 0.902439
40 GDP ALF 0.645833 0.847059
41 GDP AF3 0.645833 0.847059
42 G G 0.642857 0.888889
43 GMP 0.641975 0.835443
44 G3D 0.638298 0.935897
45 NGD 0.635514 0.91358
46 2MD 0.633027 0.894118
47 CAG 0.630631 0.840909
48 G4P 0.625 0.935897
49 U2G 0.62037 0.891566
50 FEG 0.62037 0.83908
51 MGD 0.616071 0.894118
52 ZGP 0.614679 0.872093
53 CG2 0.609091 0.891566
54 TPG 0.598291 0.804348
55 3GP 0.595506 0.898734
56 GDP 7MG 0.590476 0.86747
57 GH3 0.581633 0.924051
58 MD1 0.581197 0.894118
59 PGD 0.581197 0.926829
60 2GP 0.577778 0.911392
61 DGT 0.561224 0.878049
62 DBG 0.558333 0.902439
63 G1G 0.550847 0.880952
64 SAP 0.547368 0.924051
65 AGS 0.547368 0.924051
66 FE9 0.546219 0.8
67 G4M 0.539062 0.840909
68 U A G G 0.538462 0.888889
69 G A A A 0.529915 0.878049
70 MGP 0.525253 0.91358
71 GPX 0.524272 0.898734
72 BGO 0.521739 0.879518
73 DGI 0.520408 0.878049
74 6G0 0.52 0.91358
75 I2C FE2 CMO CMO 0.516667 0.774194
76 IDP 0.515464 0.923077
77 GGM 0.508475 0.858824
78 G1R G1R 0.508065 0.879518
79 PGD O 0.504 0.875
80 G G U 0.5 0.888889
81 GTA 0.486726 0.891566
82 P2G 0.484536 0.839506
83 GPC 0.483607 0.83908
84 G C 0.483333 0.857143
85 P1G 0.474747 0.829268
86 DG 0.474227 0.865854
87 DGP 0.474227 0.865854
88 BA3 0.46875 0.85
89 AP5 0.463918 0.85
90 B4P 0.463918 0.85
91 IMP 0.463918 0.910256
92 G2Q 0.462963 0.91358
93 G G G RPC 0.459016 0.833333
94 APC G U 0.456 0.843373
95 U G A 0.452555 0.847059
96 ATP 0.45 0.873418
97 G G G C 0.448819 0.869048
98 A2D 0.447917 0.85
99 5FA 0.445545 0.873418
100 AQP 0.445545 0.873418
101 A G C C 0.445312 0.86747
102 G7M 0.444444 0.901235
103 G U34 0.442623 0.847059
104 01G 0.442478 0.860465
105 ITT 0.44 0.825
106 SGP 0.44 0.876543
107 G C C C 0.431818 0.879518
108 AN2 0.43 0.8625
109 DG DG 0.428571 0.825581
110 A4P 0.42623 0.829545
111 UCG 0.424242 0.86747
112 C2E 0.423077 0.875
113 PCG 0.423077 0.886076
114 35G 0.423077 0.886076
115 MGO 0.420561 0.823529
116 ADP 0.42 0.873418
117 ANP 0.419048 0.851852
118 5GP 5GP 0.419048 0.839506
119 ADQ 0.418182 0.829268
120 APR 0.417476 0.85
121 AR6 0.417476 0.85
122 7DT 0.417476 0.860759
123 A G U 0.414286 0.847059
124 AD9 0.413462 0.851852
125 UP5 0.413223 0.831325
126 A22 0.412844 0.8625
127 25L 0.412281 0.8625
128 M33 0.411765 0.839506
129 JBT 0.410405 0.783505
130 ACP 0.407767 0.851852
131 ACQ 0.40566 0.851852
132 A1R 0.405405 0.8
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1AZT; Ligand: GSP; Similar sites found: 466
This union binding pocket(no: 1) in the query (biounit: 1azt.bio1) has 29 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1IWE IMP 0.0003536 0.49364 1.24378
2 1W5T ADP 0.002055 0.44092 1.24378
3 1W5T ANP 0.001768 0.43608 1.24378
4 5FJJ MAN 0.02761 0.41546 1.24378
5 3VSV XYS 0.04055 0.40233 1.24378
6 1D2E GDP 0.000000005595 0.53962 1.25945
7 4RD0 GDP 0.00000000009493 0.64029 1.49254
8 5FTB ANP 0.0002076 0.49701 1.49254
9 5FHD ADP ALF 0.0005501 0.45833 1.49254
10 4YS0 ADP 0.006795 0.41713 1.49254
11 4OEV OXL 0.02994 0.4087 1.49254
12 2B8W ALF 5GP 0.000006738 0.48518 1.52439
13 3E70 GDP 0.00001461 0.42765 1.52439
14 4B47 GDP 0.0000000001052 0.83811 1.65289
15 4IDN GNP 0.00005092 0.4987 1.74129
16 5VGR GDP 0.0002665 0.4815 1.74129
17 1OYY AGS 0.001655 0.4637 1.74129
18 5I34 GDP 0.0000181 0.42475 1.74129
19 1X6V ADP 0.0009286 0.42414 1.74129
20 3BD9 A3P 0.01839 0.40741 1.78571
21 2ZFI ADP 0.00002965 0.55111 1.91257
22 4GOX A3P 0.00204 0.42629 1.91693
23 3VM7 GLC 0.01788 0.41121 1.99005
24 1WF3 GNP 0.000000007243 0.60621 1.99336
25 3DC4 ADP 0.000009531 0.40176 2.03488
26 3BOS CDP 0.00003745 0.40082 2.06612
27 1WDT GTP 0.000000003445 0.69558 2.23881
28 1QF5 GDP 0.00004976 0.49956 2.23881
29 1YTM ATP 0.0002239 0.47546 2.23881
30 1QF5 RPL 0.00491 0.4453 2.23881
31 2BIF ANP 0.002429 0.41356 2.23881
32 2BIF SIN 0.004351 0.41356 2.23881
33 2F5X ASP 0.03225 0.40654 2.24359
34 1GOJ ADP 0.000004421 0.62977 2.25352
35 3MD0 GDP 0.000000002995 0.49983 2.25352
36 2OBM ADP 0.003373 0.46326 2.30548
37 2GWH A3P 0.00271 0.43542 2.34899
38 3BFX A3P 0.001276 0.44624 2.36486
39 4RZ3 ADP 0.0001959 0.4115 2.37288
40 1I0B PEL 0.01323 0.4151 2.40964
41 4DCT GDP 0.00000002958 0.69067 2.48756
42 4LYA ATP 0.0001403 0.51106 2.48756
43 4IEE AGS 0.001096 0.47822 2.48756
44 1U2Z SAH 0.0009903 0.40938 2.48756
45 2PL3 ADP 0.0013 0.47442 2.54237
46 4YDS ATP 0.0000682 0.54764 2.63158
47 4HI0 GDP 0.00000003542 0.64222 2.64151
48 4LC1 GDP 0.000000157 0.66499 2.67062
49 3Q9L ATP 0.00004592 0.51641 2.69231
50 1Y63 ADP 0.00001258 0.41182 2.71739
51 1G7S GDP 0.0000000005613 0.7748 2.73632
52 1MKY GDP 0.00000000005319 0.5596 2.73632
53 1F5N GNP 0.00002689 0.49181 2.73632
54 1YBH P22 0.01207 0.42042 2.73632
55 3MBI HSX 0.01971 0.41367 2.78746
56 3FYH ADP 0.006536 0.40201 2.79503
57 3ZFD ANP 0.0000004624 0.47515 2.849
58 1V8K ANP 0.000001202 0.62076 2.98507
59 1KK1 GNP 0.000000000223 0.53289 2.98507
60 4XGU ADP 0.00008808 0.50348 2.98507
61 3FKQ ATP 0.0002398 0.4836 2.98507
62 1W0J ADP 0.00006374 0.41291 2.98507
63 4QOS ADP 0.0008731 0.46722 3.01887
64 2GDJ ANP 0.0002512 0.50468 3.0303
65 4P4T GDP 0.000001504 0.57739 3.05556
66 5HCN GCP 0.0000003327 0.48366 3.06513
67 3ZQ6 ADP ALF 0.00001554 0.48202 3.08642
68 4V03 ADP 0.000009438 0.43098 3.11284
69 2AWN ADP 0.000009866 0.60959 3.14961
70 5JCP GDP ALF 0.000000008865 0.68621 3.23383
71 1TQ4 GDP 0.0000001337 0.61691 3.23383
72 2PW0 TRC 0.02335 0.40986 3.23383
73 5SXS NIZ 0.01379 0.40323 3.23383
74 2FAH GDP 0.0002355 0.40019 3.23383
75 4DKX GDP 0.000000002257 0.75717 3.24074
76 3W6G FLC 0.03333 0.40578 3.24074
77 3EZ2 ADP 0.0001185 0.52779 3.26633
78 2Q2Y MKR 0.004173 0.41016 3.26975
79 2Q2Y ADP 0.004437 0.41016 3.26975
80 4AG5 ADP 0.0001313 0.53745 3.31633
81 2OG2 MLI 0.0001904 0.53106 3.34262
82 3FVQ ATP 0.0007546 0.45231 3.34262
83 1Z0F GDP 0.00000003222 0.50055 3.35196
84 2PEZ DAT 0.001238 0.4237 3.35196
85 2PEZ GGZ 0.001238 0.4237 3.35196
86 3ZS9 ADP ALF 0.00002536 0.49282 3.38983
87 2WOJ ADP ALF 0.00003122 0.47086 3.38983
88 1QXA GLY GLY GLY 0.02604 0.41631 3.40426
89 4NON GDP 0.0000001913 0.57175 3.46154
90 2C78 GNP 0.00000000002055 0.77372 3.48259
91 2C77 GNP 0.000000000007841 0.6635 3.48259
92 1P9B GDP 0.00005631 0.51236 3.48259
93 2CE7 ADP 0.0001092 0.40145 3.48259
94 3EC1 GDP 0.00000004119 0.4998 3.52304
95 4Q1A UDP 0.01331 0.43601 3.57143
96 4Q1A 2XZ 0.01331 0.43601 3.57143
97 2QQC AG2 0.03381 0.40673 3.57143
98 3VX3 ADP 0.0002689 0.47654 3.62903
99 1G6O ADP 0.0001661 0.50165 3.63636
100 4XVU ATP 0.00005243 0.44668 3.68664
101 1Z06 GNP 0.000000001022 0.68384 3.7037
102 4A4Z ANP 0.003831 0.44544 3.73134
103 1FP6 ADP 0.00003754 0.52629 3.80623
104 1L2T ATP 0.001499 0.42853 3.82979
105 2IYL GDP 0.0000188 0.56101 3.87324
106 2RGX AP5 0.008818 0.4001 3.8835
107 1RYH GNP 0.00000000494 0.53855 3.94089
108 3R7F CP 0.01589 0.42481 3.94737
109 1UJ2 C5P 0.00109 0.41251 3.96825
110 3B9Q MLI 0.00003866 0.56521 3.97351
111 5FG3 GDP 0.0000000003919 0.52402 3.9801
112 5I0H ADP BEF 0.000001723 0.48491 3.9801
113 4WZA ADP 0.00004283 0.51134 3.98551
114 4WZA ACP 0.00004283 0.51134 3.98551
115 1RJ9 GCP 0.00007868 0.40455 4
116 5L3V GDP 0.000007033 0.44084 4.01338
117 2C04 GCP 0.00006452 0.50966 4.0404
118 4R98 GNH 0.0000000009945 0.53455 4.05904
119 5L3R GCP 0.000004017 0.53502 4.09556
120 2WIC GNP 0.00000000002 0.84556 4.11985
121 1E96 GTP 0.000000003408 0.61484 4.16667
122 1Z2A GDP 0.00000007151 0.61428 4.16667
123 1I4D GDP 0.0000002716 0.46391 4.16667
124 1YRB GDP 0.00000002835 0.67211 4.19847
125 5J1J ANP 0.00005619 0.44593 4.21053
126 2QQD AG2 0.03749 0.40304 4.21687
127 1SQ5 ADP 0.0001238 0.51372 4.22078
128 3NHB ADP 0.00007932 0.55047 4.24837
129 1G6H ADP 0.000009485 0.61033 4.28016
130 1MH1 GNP 0.000000001668 0.63151 4.30108
131 4NCN GTP 0.0000000004407 0.62699 4.47761
132 1GWN GTP 0.0000000006183 0.60601 4.47761
133 1PUJ GNP 0.00000000007902 0.59201 4.47761
134 2DPY ADP 0.001008 0.48608 4.47761
135 2C9O ADP 0.0007899 0.45144 4.47761
136 5IRN ADP 0.0000831 0.41076 4.47761
137 4WZ6 ATP 0.00004764 0.56306 4.48276
138 1HE1 AF3 0.000003893 0.61307 4.54545
139 1HE1 GDP 0.000001272 0.57398 4.54545
140 3TK1 GDP 0.000000008608 0.48521 4.54545
141 5L3W GDP 0.0001345 0.40668 4.57516
142 4H1V GNP 0.000001268 0.58769 4.60705
143 3LRE ADP 0.00000372 0.63317 4.72637
144 1SVI GDP 0.000000167 0.46812 4.72637
145 5L3S GNP 0.00001434 0.47417 4.72973
146 5CK5 GDP 0.00000008163 0.47388 4.74684
147 5BQ5 ADP BEF 0.0004303 0.4819 4.7619
148 1FNN ADP 0.0006492 0.45939 4.88432
149 2ZEJ GDP 0.0000006332 0.53379 4.8913
150 4M6T SAM 0.0447 0.40219 4.91803
151 3B5J 12D 0.00009665 0.53968 4.93827
152 2W58 ADP 0.00001846 0.59469 4.9505
153 1IHU ADP 0.00005616 0.44596 4.97512
154 1IHU AF3 0.00004458 0.4438 4.97512
155 1OS1 ATP 0.0026 0.4069 4.97512
156 1OS1 PYR 0.002985 0.40602 4.97512
157 1JJ7 ADP 0.000006135 0.62329 5
158 3A1S GDP 0.0000009967 0.61604 5.03876
159 4PPF FLC 0.000002331 0.64363 5.14286
160 2ZR9 DTP 0.0001461 0.51646 5.15759
161 1Z0A GDP 0.00000001865 0.51464 5.17241
162 4TMZ GSP 0.0000000003115 0.71388 5.21739
163 2HF9 GSP 0.00000009668 0.63878 5.30973
164 1Z6T ADP 0.0007994 0.45968 5.47264
165 4OHY ANP 0.0002696 0.45939 5.47264
166 2CK3 ANP 0.001081 0.44948 5.47945
167 2CK3 ADP 0.001942 0.4272 5.47945
168 2V7Q ATP 0.00005843 0.4072 5.47945
169 2CBZ ATP 0.000008968 0.61551 5.48523
170 5IRR GSP 0.00000003666 0.63388 5.51948
171 1K6M AGS 0.003083 0.41872 5.72139
172 2OFW ADX 0.001287 0.43066 5.76923
173 2BCG GDP 0.0000003455 0.60598 5.82524
174 3CPJ GDP 0.0000001865 0.50154 5.8296
175 3T34 GDP 0.000001678 0.55646 5.83333
176 2WJG GDP 0.0000000001771 0.81247 5.85106
177 3KJI ADP 0.0001104 0.41693 5.90551
178 5SZH GNP 0.0000000002401 0.66305 5.91133
179 3VMF GTP 0.0000000003684 0.64664 5.97015
180 3WXM GTP 0.0000000004783 0.64289 5.97015
181 1DAR GDP 0.0000000004728 0.53438 5.97015
182 3TKL GTP 0.0000000007545 0.68929 6.12245
183 2FNA ADP 0.0000546 0.4974 6.16247
184 4ZG4 VO4 ADP 0.000005096 0.48089 6.21891
185 2CJW GDP 0.0000000007961 0.77981 6.25
186 1JI0 ATP 0.00008944 0.54145 6.25
187 1G4U GDP 0.00000118 0.5821 6.26632
188 1G4U AF3 0.00005779 0.55671 6.26632
189 1VG8 GNP 0.0000000001067 0.67568 6.28019
190 1VG0 GDP 0.00000006917 0.51169 6.28019
191 1OIX GDP 0.00000000079 0.63664 6.28272
192 1OIV GDP 0.0000000865 0.56156 6.28272
193 2QEN ADP 0.00003765 0.42725 6.28571
194 3TNF GNP 0.0000000003604 0.66399 6.32184
195 4LHW GNP 0.000000002806 0.65805 6.32184
196 3KTA AP5 0.000504 0.4736 6.35838
197 3W5J GDP 0.00000007718 0.43012 6.37255
198 5J6Y BGC 0.02204 0.41742 6.38298
199 5J6Y GLC 0.02204 0.41742 6.38298
200 3QBT GNP 0.0000000003213 0.6963 6.42857
201 2EW1 GNP 0.000000002235 0.60557 6.46766
202 1G16 GDP 0.0000006983 0.50937 6.47059
203 1YZN GNP 0.0000000009463 0.66955 6.48649
204 1YVD GNP 0.000000002763 0.65832 6.50888
205 2G77 GDP 0.000000004802 0.69839 6.56566
206 2G77 AF3 0.0000001518 0.69662 6.56566
207 1KY3 GDP 0.00000009543 0.50683 6.59341
208 4LPS GDP 0.0000002248 0.64764 6.61157
209 2WJH GDP 0.000000001126 0.54063 6.62651
210 2WJH FLC 0.00000009464 0.49426 6.62651
211 3SFV GDP 0.0000001194 0.52796 6.62983
212 5JCZ GDP 0.00000007136 0.63665 6.70391
213 5M04 GDP 0.0000000005328 0.52138 6.71642
214 1JWY GDP 0.00000005452 0.50945 6.71642
215 4OI4 ATP 0.0007659 0.40512 6.71642
216 1JWY ADP 0.00004664 0.40246 6.71642
217 4LX0 BEF GDP 0.0000000005945 0.64849 6.77966
218 4HSE ADP 0.0002619 0.49782 6.80101
219 5KSP GDP 0.000003205 0.44568 6.84211
220 3NKV GNP 0.000000001574 0.62629 6.85714
221 2HV8 GTP 0.000000007468 0.60217 6.97674
222 2BEK ATP 0.0002154 0.47176 7.00389
223 5K5Z ANP 0.0001126 0.44242 7.00637
224 1TU3 GNP 0.0000000009543 0.63355 7.01754
225 3RWO GDP 0.00000002793 0.57978 7.02703
226 1VG1 GDP 0.000000008131 0.51733 7.02703
227 1VG9 GDP 0.00000002588 0.50568 7.02703
228 2F9L GDP 0.0000001425 0.60165 7.03518
229 1H65 GDP 0.00005381 0.44442 7.03704
230 1R2Q GNP 0.0000000002661 0.68941 7.05882
231 1YZQ GNP 0.0000000001945 0.66607 7.05882
232 1EK0 GNP 0.0000000007756 0.63666 7.05882
233 4GBM A3P 0.005122 0.4094 7.12074
234 3MJH GTP 0.0000000004577 0.69005 7.14286
235 2EFE GNH 0.0000003284 0.49383 7.18232
236 2D7C GTP 0.000000001062 0.63158 7.18563
237 4IOK ADP 0.001391 0.41377 7.21393
238 4IOK XPO 0.0008794 0.40951 7.21393
239 3E5H GNP 0.000000000887 0.63595 7.30337
240 4BQS ADP 0.00007293 0.53156 7.38636
241 4BQS K2Q 0.003158 0.41156 7.38636
242 4DSU GDP 0.00000001448 0.59677 7.40741
243 3QXC ATP 0.004307 0.40378 7.43802
244 4R43 GDP 0.0002078 0.5088 7.46269
245 1A5Z FBP 0.004479 0.45335 7.52351
246 5N69 ADP 0.00006765 0.41094 7.53769
247 5G41 AP5 0.009979 0.40068 7.62332
248 3DEF GDP 0.00001348 0.54706 7.63359
249 1Z08 GNP 0.00000001021 0.64995 7.64706
250 3RAB GNP 0.0000000002331 0.65566 7.69231
251 1B7T ADP 0.0001415 0.50497 7.69231
252 5H56 TYD 0.003233 0.40468 7.69231
253 5H56 ADP 0.003233 0.40468 7.69231
254 4PFO ADP 0.0002374 0.43344 7.71144
255 3B7G ANP 0.003105 0.44532 7.82609
256 2WKQ GTP 0.000000003277 0.67077 7.83133
257 3FB4 AP5 0.003952 0.41219 7.87037
258 1S8F GDP 0.00000001153 0.60664 7.9096
259 2FJU GSP 0.0000000019 0.59298 7.9602
260 5KSZ GCP 0.00003183 0.43008 7.9602
261 2A9K GDP 0.00000002884 0.53025 8.02139
262 1D5C GDP 0.00000007554 0.51852 8.02469
263 2HT6 GDP 0.0000000004471 0.52087 8.04598
264 2VB6 ADP BEF 0.0001669 0.42751 8.05369
265 2C5L GTP 0.0000000002865 0.66018 8.09249
266 5TAR GDP 0.00000004018 0.66504 8.10811
267 2FH5 GTP 0.0000000003951 0.60913 8.10811
268 5TB5 GDP 0.0000000241 0.51521 8.10811
269 3GJ8 GDP 0.00000000339 0.73664 8.1448
270 3GJ7 GDP 0.000000007729 0.73042 8.1448
271 3GJ0 GDP 0.000000008942 0.72725 8.1448
272 3GJ5 GDP 0.000000003721 0.53114 8.1448
273 3GJ4 GDP 0.000000008965 0.51095 8.1448
274 2J5V PCA 0.01529 0.43217 8.17439
275 5WDR GNP 0.0000000001289 0.67313 8.18713
276 4K81 GTP 0.0000000008752 0.64947 8.18713
277 5XCO GDP 0.000000105 0.50846 8.18713
278 1SKQ GDP 0.00000000002089 0.87411 8.20895
279 3QOX SAH 0.0004075 0.42351 8.20895
280 5O2T GSP 0.0000000008832 0.67075 8.28402
281 1IBR GNP 0.00000000008873 0.71058 8.33333
282 4HAT GNP 0.00000000007369 0.6899 8.33333
283 3GJX GTP 0.0000000001538 0.67038 8.33333
284 5BXQ GDP 0.000000004881 0.52711 8.33333
285 1BO4 COA 0.006686 0.43331 8.33333
286 2A5J GDP 0.00000005691 0.66712 8.37696
287 4HDO GNP 0.0000000003403 0.68728 8.38323
288 1GUA GNP 0.0000000005703 0.67833 8.38323
289 3X1Z GNP 0.0000000007461 0.65211 8.38323
290 4HDQ GNP 0.000000001703 0.63174 8.38323
291 1KAO GDP 0.000000005411 0.55295 8.38323
292 1CLU DBG 0.0000002134 0.58723 8.43373
293 5UFQ GNP 0.00000004655 0.57098 8.43373
294 3Q72 GNP 0.000000004405 0.50175 8.43373
295 3SBD GNP 0.000000002331 0.66132 8.55615
296 1UAD GNP 0.0000000003073 0.65077 8.57143
297 2NCD ADP 0.00002457 0.57755 8.57143
298 3FWY ADP 0.00001447 0.44246 8.59873
299 3IO3 ADP 0.00003439 0.43419 8.62069
300 1KK8 BEF ADP 0.000105 0.5 8.63309
301 3WYF GTP 0.0000000001699 0.67621 8.6758
302 3M1I GTP 0.0000000001106 0.67539 8.6758
303 4KVG GTP 0.0000000008967 0.63477 8.84615
304 5E95 GDP 0.00000002233 0.66787 8.92857
305 1U8Z GDP 0.00000000874 0.65279 8.92857
306 1ZUI SKM 0.0006955 0.43761 8.92857
307 1UPR 4IP 0.02095 0.42763 8.94309
308 4U5X GNP 0.00000004001 0.53611 8.98876
309 5UQW GDP 0.00000007875 0.55684 8.99471
310 1WQ1 AF3 0.00000003064 0.7417 9.03614
311 3DDC GNP 0.0000000002552 0.69227 9.03614
312 1NVV GNP 0.0000000001892 0.66719 9.03614
313 1WQ1 GDP 0.0000000363 0.6267 9.03614
314 3KUD GDP 0.000000002802 0.58447 9.03614
315 1T0S BML 0.02052 0.41739 9.30233
316 4CVN ADP 0.00009267 0.54064 9.42408
317 3CH5 GDP 0.000000003286 0.53232 9.61539
318 1G7C 5GP 0.0000001096 0.67279 9.70149
319 4E03 ADP 0.00002166 0.42234 9.70874
320 2CHG ANP 0.0003255 0.40665 9.73451
321 4GDX GLU 0.03959 0.40401 9.74359
322 1M7B GTP 0.000000001378 0.70408 9.78261
323 5UWQ GNP 0.00000000005328 0.71942 9.79021
324 5UWJ GNP 0.00000000006317 0.71647 9.79021
325 5UWH GNP 0.0000000000658 0.71576 9.79021
326 5UWP GNP 0.00000000007847 0.68883 9.79021
327 5UWI GNP 0.00000000004959 0.68825 9.79021
328 5UWU GNP 0.00000000005533 0.68658 9.79021
329 5DIF GNP 0.00000000005557 0.68647 9.79021
330 5UWR GNP 0.0000000000574 0.6859 9.79021
331 5UWW GNP 0.00000000006228 0.68471 9.79021
332 5DI9 GNP 0.0000000001037 0.68429 9.79021
333 5DHF GNP 0.00000000006742 0.6834 9.79021
334 5UWS GNP 0.0000000001182 0.68217 9.79021
335 3REF GDP 0.0000001406 0.60877 9.79381
336 2XTN GTP 0.0000108 0.52235 9.82906
337 2FFQ GSP 0.00000000009093 0.6786 9.94152
338 5GOE GDP 0.000000003036 0.7279 9.95025
339 1WA5 GTP 0.0000000002176 0.65733 10.2273
340 1B0U ATP 0.002988 0.43748 10.3053
341 1G8S MET 0.008276 0.44 10.4348
342 2GJ8 ALF GDP 0.000000009606 0.62938 10.4651
343 1G3Q ADP 0.000003701 0.5882 10.5485
344 5KUT GDP 0.0000003212 0.47199 10.582
345 3WYA GDP 0.00000000001218 0.57177 10.5991
346 4XTR ATP 0.00004122 0.44997 10.8108
347 4XTR ADP 0.00002791 0.43684 10.8108
348 1LVG ADP 0.000004246 0.40461 11.1111
349 4JD0 1KH 0.03382 0.40635 11.1554
350 4C4P GNP 0.000000001528 0.63374 11.215
351 2W2X GSP 0.000000003204 0.58285 11.2903
352 1LFD GNP 0.0000000001843 0.65945 11.4943
353 1M2O GNP 0.0000000003095 0.64881 11.5789
354 3BC1 GNP 0.0000000005947 0.64109 11.8644
355 1W7J ADP BEF 0.00007991 0.50541 11.9205
356 1NVU GTP 0.0000000002128 0.66519 11.9403
357 4MKF AP5 0.005366 0.40786 11.9816
358 2RCN GDP 0.000000009355 0.50302 12.2905
359 4MKG AP5 0.004219 0.41104 12.4424
360 1QHH ATP 0.006379 0.43 12.5749
361 3U6B GDP 0.0000000001626 0.82841 12.6904
362 4G5G GDP 0.0000000005082 0.78956 12.6904
363 3U6K GDP 0.000000001473 0.76643 12.6904
364 5JBQ GDP 0.0000000004167 0.53653 12.6904
365 4PC3 GDP 0.00000003139 0.51844 12.6904
366 2BVN GNP 0.0000000001292 0.78146 12.7226
367 1D8T GDP 0.0000000007065 0.53144 12.7226
368 2VOH CIT 0.01483 0.42249 12.7389
369 3PQC GDP 0.000006385 0.56923 12.8205
370 1S3G AP5 0.004885 0.40847 12.9032
371 4DID GDP 0.0000003915 0.47379 12.9534
372 1GRN AF3 0.0000002668 0.67432 13.089
373 1GRN GDP 0.0000002011 0.62423 13.089
374 1A4R GDP 0.0000002539 0.51389 13.089
375 1A4R GNH 0.0000003115 0.50518 13.089
376 2NGR GDP 0.00000006168 0.50034 13.089
377 4ITR GDP 0.000002556 0.47623 13.089
378 2NGR AF3 0.00000001997 0.47112 13.089
379 2HCJ GDP 0.0000000003338 0.52966 13.1343
380 3WYG GTP 0.00000000009472 0.68563 13.1579
381 2WMO GTP 0.0000000062 0.53678 13.1579
382 4ZKD GDP 0.0000000006406 0.64597 13.1841
383 3T5G GDP 0.00000003396 0.5105 13.2597
384 1X1R GDP 0.0000000987 0.56591 13.4831
385 1Z0J GTP 0.000000002386 0.65352 13.5593
386 1XTQ GDP 0.00000001797 0.57325 13.5593
387 4J0Q GDP 0.0000000001174 0.83567 13.6259
388 4P3Y GDP 0.0000000001415 0.53569 13.7363
389 4YC7 GNP 0.000000004193 0.58725 13.8122
390 1KMQ GNP 0.0000000008854 0.61855 14.1304
391 4XOI GTP 0.000000001268 0.6215 14.4444
392 2UZI GTP 0.0000000003851 0.64753 14.9123
393 3GJ3 GDP 0.000000004717 0.51668 15.1515
394 3BFV ADP 0.00001347 0.41114 15.4982
395 1NF3 GNP 0.00000000298 0.61621 15.625
396 2QN6 GDP 0.0000000002839 0.816 16.129
397 2ZTS ADP 0.001377 0.44477 16.7331
398 3LDJ SCR 0.01029 0.44552 17.2414
399 1F6B GDP 0.000000001692 0.53274 17.6768
400 1ZC3 GNP 0.0000000001138 0.67488 17.6991
401 1DS6 GDP 0.0000001688 0.47505 17.7778
402 2Y8E GNP 0.0000000001096 0.71528 18.4358
403 2GCN GDP 0.0000004617 0.51616 18.9055
404 4M9Q GNP 0.00000000000316 0.8087 18.9427
405 3T12 GDP ALF 0.0000000000005678 0.84077 19.1919
406 3T1O GDP 0.00000000004606 0.58484 19.1919
407 2BME GNP 0.0000000003103 0.65073 19.3548
408 1OW3 GDP 0.0000002559 0.50741 19.6891
409 2GCO GNP 0.000000004046 0.55951 19.9005
410 3DOE GTP 0.000000000004032 0.69521 20.3125
411 5IRC GDP 0.0000005254 0.48314 20.4301
412 4ZI2 GNP 0.000000000006545 0.67902 20.5263
413 3LXR GDP 0.0000008612 0.61077 20.5405
414 5HPY GDP 0.0000001784 0.51158 20.5405
415 4D0N GDP 0.0000001383 0.47648 20.5405
416 1QF9 C5P 0.005509 0.40311 20.6186
417 1QF9 ADP 0.005509 0.40311 20.6186
418 1QF9 ALF 0.005509 0.40311 20.6186
419 4GOJ GNP 0.000000000003385 0.68772 20.6349
420 1YZG GDP 0.00000000001721 0.58351 20.6704
421 1KSH GDP 0.00000000001376 0.65776 20.9677
422 1ION ADP 0.00001011 0.43154 20.9877
423 4BAS GNP 0.0000000000008247 0.70527 21.1055
424 4XSH GSP 0.00000001406 0.55275 21.229
425 1ZJ6 G3D 0.00000000001663 0.84947 21.3904
426 1TX4 ALF GDP 0.00000000145 0.68571 21.4689
427 1FZQ GDP 0.0000000004374 0.53773 21.547
428 5DI3 GNP 0.000000000009396 0.78835 21.6216
429 1UPT GTP 0.00000000001874 0.661 21.6374
430 1O3Y GTP 0.000000000002694 0.80092 21.6867
431 2J59 GTP 0.000000000003383 0.79675 21.6867
432 4D0G GTP 0.00000001257 0.57075 21.7143
433 3AQ4 GDP 0.00000000001922 0.8464 21.7391
434 5UWT GNP 0.0000000000648 0.68399 21.7391
435 1NJF AGS 0.0006024 0.40583 22
436 1NJF ADP 0.0004432 0.40078 22
437 1CXZ GSP 0.0000000006587 0.61455 22.093
438 2QTV GNP 0.0000000001102 0.65519 22.1557
439 2A5F GTP 0.0000000000004297 0.73968 22.2857
440 4KAX GTP 0.0000000000007476 0.70717 22.4852
441 4YLG GDP 0.0000000003589 0.58523 22.5434
442 1S9D GDP 0.00000000002456 0.84119 22.561
443 1RE0 GDP 0.00000000002648 0.54674 22.561
444 1MR3 G3D 0.0000000001732 0.55782 22.6519
445 5EE5 GTP 0.00000000001409 0.66643 22.807
446 3Q85 GNP 0.000000003163 0.51601 23.0769
447 3PCR GTP 0.000000000001164 0.81631 23.4568
448 2J0V GDP 0.0000009682 0.46476 23.5849
449 3N5C GDP 0.00000000002729 0.8531 24.0741
450 1R4A GNP 0.000000000005971 0.70013 24.2424
451 2X77 GDP 0.00000004514 0.6817 24.8677
452 1Z0K GTP 0.000000001024 0.69209 25
453 4V0K GDP 0.00000001252 0.63879 25.4438
454 1GXU 2HP 0.00308 0.44535 26.3736
455 1ZD9 GDP 0.000000001006 0.71951 27.6596
456 1J2J GTP 0.00000000002512 0.76002 28.8889
457 1NRJ GTP 0.0000000003756 0.61141 29.1139
458 3CNL GNP 0.000000001237 0.78322 29.771
459 2W83 GTP 0.000000000001066 0.81791 29.8701
460 3ZIA ADP 0.0000801 0.41102 31.1475
461 3ZIA ATP 0.00004451 0.40423 31.1475
462 3WY9 GDP 0.0000000001086 0.83741 31.25
463 1M7G ADX 0.001106 0.4242 31.2796
464 1M7G AV2 0.000006585 0.41263 31.2796
465 1M7G ADP 0.001858 0.41252 31.2796
466 5UWO GNP 0.00000000006701 0.71545 35
Pocket No.: 2; Query (leader) PDB : 1AZT; Ligand: GSP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 1azt.bio1) has 28 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
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