Receptor
PDB id Resolution Class Description Source Keywords
1AZT 2.3 Å EC: 4.-.-.- GS-ALPHA COMPLEXED WITH GTP-GAMMA-S BOS TAURUS HYDROLASE SIGNAL TRANSDUCING PROTEIN GTP-BINDING PROTEIN
Ref.: CRYSTAL STRUCTURE OF THE ADENYLYL CYCLASE ACTIVATOR SCIENCE V. 278 1943 1997
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GSP A:413;
B:411;
Valid;
Valid;
none;
none;
submit data
539.246 C10 H16 N5 O13 P3 S c1nc2...
MG A:403;
B:406;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
PO4 A:404;
A:405;
A:406;
A:407;
A:408;
A:409;
A:410;
A:411;
A:412;
B:403;
B:404;
B:405;
B:407;
B:408;
B:409;
B:410;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
94.971 O4 P [O-]P...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1AZT 2.3 Å EC: 4.-.-.- GS-ALPHA COMPLEXED WITH GTP-GAMMA-S BOS TAURUS HYDROLASE SIGNAL TRANSDUCING PROTEIN GTP-BINDING PROTEIN
Ref.: CRYSTAL STRUCTURE OF THE ADENYLYL CYCLASE ACTIVATOR SCIENCE V. 278 1943 1997
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 33 families.
1 1AZT - GSP C10 H16 N5 O13 P3 S c1nc2c(n1C....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 31 families.
1 1AZT - GSP C10 H16 N5 O13 P3 S c1nc2c(n1C....
50% Homology Family (24)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 1GFI - ALF GDP n/a n/a
2 4N0E - GDP C10 H15 N5 O11 P2 c1nc2c(n1C....
3 4PAM - GDP C10 H15 N5 O11 P2 c1nc2c(n1C....
4 1AS0 - GSP C10 H16 N5 O13 P3 S c1nc2c(n1C....
5 1GIL - GSP C10 H16 N5 O13 P3 S c1nc2c(n1C....
6 3FFA Kd = 0.69 uM GSP C10 H16 N5 O13 P3 S c1nc2c(n1C....
7 1GDD - GDP C10 H15 N5 O11 P2 c1nc2c(n1C....
8 4PAO - GSP C10 H16 N5 O13 P3 S c1nc2c(n1C....
9 1BOF - GDP C10 H15 N5 O11 P2 c1nc2c(n1C....
10 1CIP - GNP C10 H17 N6 O13 P3 c1nc2c(n1C....
11 1GIA - GSP C10 H16 N5 O13 P3 S c1nc2c(n1C....
12 4N0D - GSP C10 H16 N5 O13 P3 S c1nc2c(n1C....
13 1AS3 - GDP C10 H15 N5 O11 P2 c1nc2c(n1C....
14 1SVS Kd = 2.3 nM GNP C10 H17 N6 O13 P3 c1nc2c(n1C....
15 1SVK Kd = 1.1 nM ALF GDP n/a n/a
16 4PAN - GDP C10 H15 N5 O11 P2 c1nc2c(n1C....
17 4PAQ - GSP C10 H16 N5 O13 P3 S c1nc2c(n1C....
18 1TAG - GDP C10 H15 N5 O11 P2 c1nc2c(n1C....
19 1TND - GSP C10 H16 N5 O13 P3 S c1nc2c(n1C....
20 1TAD - GDP C10 H15 N5 O11 P2 c1nc2c(n1C....
21 1AZT - GSP C10 H16 N5 O13 P3 S c1nc2c(n1C....
22 1BH2 - GSP C10 H16 N5 O13 P3 S c1nc2c(n1C....
23 2XTZ - GSP C10 H16 N5 O13 P3 S c1nc2c(n1C....
24 1ZCB - GDP C10 H15 N5 O11 P2 c1nc2c(n1C....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GSP; Similar ligands found: 120
No: Ligand ECFP6 Tc MDL keys Tc
1 GSP 1 1
2 GP3 0.897436 0.925
3 GTP 0.853659 0.948718
4 GNH 0.829268 0.936709
5 GDP 0.817073 0.948718
6 G1R 0.8 0.936709
7 GCP 0.77907 0.925
8 GNP 0.770115 0.925
9 GMV 0.767442 0.925
10 G 0.756098 0.935897
11 5GP 0.756098 0.935897
12 G2R 0.747253 0.91358
13 GDD 0.744681 0.91358
14 GKE 0.744681 0.91358
15 GDC 0.744681 0.91358
16 GPG 0.73913 0.91358
17 GTG 0.736842 0.891566
18 G3A 0.729167 0.925
19 G5P 0.721649 0.925
20 GFB 0.71875 0.91358
21 GDR 0.71875 0.91358
22 GAV 0.714286 0.987179
23 GP2 0.712644 0.91358
24 Y9Z 0.708333 0.860465
25 JB2 0.69697 0.91358
26 GKD 0.69697 0.91358
27 GDP MG 0.696629 0.878049
28 G2P 0.692308 0.91358
29 GPD 0.69 0.880952
30 GDX 0.69 0.925
31 GCP G 0.677419 0.888889
32 ALF 5GP 0.67033 0.847059
33 0O2 0.666667 0.935897
34 GTP MG 0.666667 0.878049
35 BEF GDP 0.666667 0.847059
36 YGP 0.663265 0.858824
37 JB3 0.657143 0.902439
38 GDP AF3 0.645833 0.847059
39 GDP ALF 0.645833 0.847059
40 GMP 0.641975 0.835443
41 G3D 0.638298 0.935897
42 NGD 0.635514 0.91358
43 2MD 0.633027 0.894118
44 CAG 0.630631 0.840909
45 G4P 0.625 0.935897
46 FEG 0.62037 0.83908
47 U2G 0.62037 0.891566
48 G G 0.617647 0.901235
49 MGD 0.616071 0.894118
50 CG2 0.609091 0.891566
51 TPG 0.598291 0.804348
52 3GP 0.595506 0.898734
53 GDP 7MG 0.590476 0.86747
54 MD1 0.581197 0.894118
55 PGD 0.581197 0.926829
56 2GP 0.577778 0.911392
57 DGT 0.561224 0.878049
58 DBG 0.558333 0.902439
59 G1G 0.550847 0.880952
60 SAP 0.547368 0.924051
61 AGS 0.547368 0.924051
62 FE9 0.546219 0.8
63 G4M 0.539062 0.840909
64 G A A A 0.529915 0.878049
65 MGP 0.525253 0.91358
66 GPX 0.524272 0.898734
67 BGO 0.521739 0.879518
68 DGI 0.520408 0.878049
69 I2C FE2 CMO CMO 0.516667 0.774194
70 IDP 0.515464 0.923077
71 GGM 0.508475 0.858824
72 G1R G1R 0.508065 0.879518
73 PGD O 0.504 0.875
74 G G U 0.5 0.888889
75 GTA 0.486726 0.891566
76 P2G 0.484536 0.839506
77 GPC 0.483607 0.83908
78 G C 0.483333 0.857143
79 P1G 0.474747 0.829268
80 DGP 0.474227 0.865854
81 DG 0.474227 0.865854
82 BA3 0.46875 0.85
83 IMP 0.463918 0.910256
84 B4P 0.463918 0.85
85 AP5 0.463918 0.85
86 G2Q 0.462963 0.91358
87 G G G RPC 0.459016 0.833333
88 U G A 0.452555 0.847059
89 ATP 0.45 0.873418
90 G G G C 0.448819 0.869048
91 A2D 0.447917 0.85
92 AQP 0.445545 0.873418
93 5FA 0.445545 0.873418
94 G7M 0.444444 0.901235
95 G U34 0.442623 0.847059
96 01G 0.442478 0.860465
97 ITT 0.44 0.825
98 SGP 0.44 0.876543
99 G C C C 0.431818 0.879518
100 DG DG 0.428571 0.825581
101 A4P 0.42623 0.829545
102 PCG 0.423077 0.886076
103 35G 0.423077 0.886076
104 C2E 0.423077 0.875
105 MGO 0.420561 0.823529
106 ADP 0.42 0.873418
107 ANP 0.419048 0.851852
108 5GP 5GP 0.419048 0.839506
109 ADQ 0.418182 0.829268
110 APR 0.417476 0.85
111 AR6 0.417476 0.85
112 AD9 0.413462 0.851852
113 UP5 0.413223 0.831325
114 A22 0.412844 0.8625
115 25L 0.412281 0.8625
116 M33 0.411765 0.839506
117 JBT 0.410405 0.783505
118 ACP 0.407767 0.851852
119 ACQ 0.40566 0.851852
120 A1R 0.405405 0.8
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1AZT; Ligand: GSP; Similar sites found: 615
This union binding pocket(no: 1) in the query (biounit: 1azt.bio1) has 29 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc)
1 1CS4 GSP 8.561e-18 0.97752
2 1FQK ALF 0.00000000001079 0.93744
3 1FQJ GDP 0.00000000000000322 0.9373
4 1FQJ GDP 0.000000000000001665 0.93609
5 1FQK GDP 0.000000000000002554 0.92827
6 1FQJ ALF 0.000000000007959 0.92813
7 1FQK ALF 0.000000000008597 0.92625
8 1FQK GDP 0.00000000000000322 0.92448
9 1FQJ ALF 0.00000000001016 0.92212
10 3CX8 GSP 4.688e-16 0.89794
11 1SKQ GDP 0.00000000002089 0.87411
12 3N5C GDP 0.00000000002729 0.8531
13 3N5C GDP 0.00000000001615 0.85008
14 1ZJ6 G3D 0.00000000001663 0.84947
15 1ZJ6 G3D 0.00000000001663 0.84947
16 1ZJ6 G3D 0.00000000001663 0.84947
17 3AQ4 GDP 0.00000000001922 0.8464
18 2WIC GNP 0.00000000002 0.84556
19 2WIC GNP 0.00000000002 0.84556
20 3AQ4 GDP 0.00000000002312 0.84248
21 1S9D GDP 0.00000000002456 0.84119
22 3T12 GDP ALF 0.0000000000005678 0.84077
23 3WY9 GDP 0.0000000001002 0.83919
24 4B47 GDP 0.0000000001052 0.83811
25 3WY9 GDP 0.0000000001086 0.83741
26 4J0Q GDP 0.0000000001105 0.83702
27 4J0Q GDP 0.0000000001164 0.83586
28 4J0Q GDP 0.0000000001174 0.83567
29 3U6B GDP 0.000000000128 0.83374
30 4J0Q GDP 0.0000000001405 0.83166
31 3U6B GDP 0.0000000001626 0.82841
32 2ODE ALF GDP 0.000000000000004108 0.82621
33 1SKQ GDP 0.00000000005827 0.82286
34 2W83 GTP 0.000000000001066 0.81791
35 3PCR GTP 0.000000000001164 0.81631
36 2QN6 GDP 0.0000000002839 0.816
37 2WJG GDP 0.0000000001771 0.81247
38 4M9Q GNP 0.000000000002966 0.80988
39 2WJG GDP 0.0000000003746 0.80983
40 4M9Q GNP 0.00000000000316 0.8087
41 4M9Q GNP 0.000000000003299 0.8079
42 4J0Q GDP 0.0000000004305 0.80673
43 2J59 GTP 0.00000000000381 0.80521
44 2OM2 GDP 0.000000000007084 0.8045
45 1O3Y GTP 0.000000000002694 0.80092
46 2J59 GTP 0.00000000000295 0.79926
47 2J59 GTP 0.000000000003004 0.79893
48 1GP2 GDP 0.000000000003097 0.79837
49 2J59 GTP 0.000000000003383 0.79675
50 2J59 GTP 0.000000000004107 0.7932
51 2J59 GTP 0.000000000004842 0.79018
52 4G5G GDP 0.0000000005082 0.78956
53 3CNL GNP 0.000000001237 0.78322
54 2BVN GNP 0.0000000001219 0.78265
55 2BVN GNP 0.0000000001292 0.78146
56 2CJW GDP 0.0000000007961 0.77981
57 3U6K GDP 0.0000000008126 0.77936
58 4NON GDP 0.0000000008605 0.77812
59 1G7S GDP 0.0000000005613 0.7748
60 2C78 GNP 0.00000000002055 0.77372
61 2OM2 GDP 0.00000000002079 0.77351
62 1O3Y GTP 0.000000000008174 0.77065
63 1Y3A GDP 0.00000000000002387 0.77017
64 3U6K GDP 0.000000001473 0.76643
65 1J2J GTP 0.00000000002512 0.76002
66 4DKX GDP 0.000000002257 0.75717
67 1GOT GDP 0.00000000000005296 0.7446
68 1WQ1 AF3 0.00000003064 0.7417
69 3GJ7 GDP 0.000000002882 0.74008
70 2A5F GTP 0.0000000000004297 0.73968
71 3GJ8 GDP 0.00000000339 0.73664
72 1A2K GDP 0.000000003413 0.73649
73 1A2K GDP 0.000000003413 0.73649
74 3GJ8 GDP 0.000000003549 0.73567
75 3GJ7 GDP 0.000000007729 0.73042
76 1A2K GDP 0.00000001517 0.7274
77 3GJ0 GDP 0.000000008942 0.72725
78 4DKX GDP 0.000000005489 0.72641
79 2Y8E GNP 0.00000000007399 0.72222
80 2Y8E GNP 0.00000000007399 0.72222
81 3AB3 GDP 0.00000000000009137 0.72124
82 1ZD9 GDP 0.000000001006 0.71951
83 3AB3 GDP 0.0000000000001087 0.71877
84 1Z0K GTP 0.0000000002852 0.7155
85 2Y8E GNP 0.0000000001096 0.71528
86 4TMZ GSP 0.0000000003115 0.71388
87 4TMZ GSP 0.0000000003298 0.71284
88 1IBR GNP 0.0000000000871 0.7109
89 1IBR GNP 0.00000000008873 0.71058
90 4V0K GDP 0.000000001783 0.70839
91 4KAX GTP 0.0000000000007476 0.70717
92 4BAS GNP 0.0000000000008247 0.70527
93 4BAS GNP 0.0000000000008247 0.70527
94 1M7B GTP 0.000000001378 0.70408
95 4LHW GNP 0.0000000003352 0.70387
96 1Z08 GNP 0.0000000001345 0.70337
97 1Z08 GNP 0.0000000002277 0.70237
98 3TH5 GNP 0.000000002472 0.70203
99 1R4A GNP 0.000000000005971 0.70013
100 2G77 GDP 0.000000004802 0.69839
101 2G77 AF3 0.0000001518 0.69662
102 3QBT GNP 0.0000000003213 0.6963
103 1WDT GTP 0.000000003445 0.69558
104 3DOE GTP 0.000000000004032 0.69521
105 3QBT GNP 0.0000000003444 0.69508
106 3DDC GNP 0.0000000002552 0.69227
107 3DDC GNP 0.0000000002552 0.69227
108 1Z0K GTP 0.000000001024 0.69209
109 3QBT GNP 0.0000000004201 0.69157
110 4DCT GDP 0.00000002958 0.69067
111 3MJH GTP 0.0000000004577 0.69005
112 4LHW GNP 0.0000000004613 0.68991
113 4HAT GNP 0.00000000007369 0.6899
114 1R2Q GNP 0.0000000002661 0.68941
115 3TKL GTP 0.0000000007545 0.68929
116 4GOJ GNP 0.000000000003385 0.68772
117 4HDO GNP 0.0000000003403 0.68728
118 1YZK GNP 0.0000000008842 0.68644
119 2CL6 CAG 0.000000000576 0.686
120 1TX4 ALF GDP 0.00000000145 0.68571
121 3TH5 GNP 0.00000001453 0.68567
122 3QBT GNP 0.0000000005878 0.68564
123 3WYG GTP 0.00000000009472 0.68563
124 1VG8 GNP 0.00000000006094 0.68439
125 1VG8 GNP 0.00000000006299 0.68389
126 1Z06 GNP 0.000000001022 0.68384
127 2X77 GDP 0.00000004514 0.6817
128 2FFQ GSP 0.00000000009093 0.6786
129 1GUA GNP 0.0000000005703 0.67833
130 3GJ0 GDP 0.0000000213 0.67791
131 3MJH GTP 0.000000000604 0.67733
132 3WYF GTP 0.0000000001699 0.67621
133 1VG8 GNP 0.0000000001067 0.67568
134 1VG8 GNP 0.0000000001065 0.67562
135 3M1I GTP 0.0000000001106 0.67539
136 1ZC3 GNP 0.0000000001138 0.67488
137 1GRN AF3 0.0000002668 0.67432
138 1G7C 5GP 0.0000001096 0.67279
139 4LHW GNP 0.000000001222 0.67272
140 1YRB GDP 0.00000002835 0.67211
141 4LHW GNP 0.000000001307 0.67153
142 2WKQ GTP 0.000000003277 0.67077
143 3GJX GTP 0.0000000001538 0.67038
144 3GJX GTP 0.0000000001552 0.67022
145 1YZN GNP 0.0000000009463 0.66955
146 3WYF GTP 0.000000000263 0.66914
147 1NVV GNP 0.0000000001892 0.66719
148 1NVV GNP 0.0000000001892 0.66719
149 1NVV GNP 0.0000000001892 0.66719
150 1NVV GNP 0.0000000001892 0.66719
151 2A5J GDP 0.00000005691 0.66712
152 4K81 GTP 0.0000000001891 0.6668
153 1YZQ GNP 0.0000000001945 0.66607
154 1TU3 GNP 0.0000000003226 0.6657
155 1NVU GTP 0.0000000002128 0.66519
156 1NVU GTP 0.0000000002128 0.66519
157 4LC1 GDP 0.000000157 0.66499
158 4GOJ GNP 0.000000000007291 0.66476
159 3TNF GNP 0.0000000003604 0.66399
160 2C77 GNP 0.000000000007841 0.6635
161 1UPT GTP 0.00000000001874 0.661
162 2C5L GTP 0.0000000002787 0.66063
163 2C5L GTP 0.0000000002865 0.66018
164 1ZC3 GNP 0.0000000001675 0.65993
165 1M2O GNP 0.00000000008056 0.65969
166 1LFD GNP 0.0000000001843 0.65945
167 1YVD GNP 0.000000002763 0.65832
168 4LHW GNP 0.000000002806 0.65805
169 1KSH GDP 0.00000000001376 0.65776
170 1WA5 GTP 0.0000000002176 0.65733
171 4K81 GTP 0.0000000005453 0.6572
172 3RAB GNP 0.0000000002331 0.65566
173 2QTV GNP 0.0000000001102 0.65519
174 1Z0J GTP 0.000000002386 0.65352
175 1U8Z GDP 0.00000000874 0.65279
176 1Z08 GNP 0.000000009066 0.65212
177 2GJ8 ALF GDP 0.000000002731 0.65118
178 3BC1 GNP 0.0000000003044 0.65088
179 1UAD GNP 0.0000000003073 0.65077
180 2BME GNP 0.0000000003103 0.65073
181 1Z08 GNP 0.00000001021 0.64995
182 1Z08 GNP 0.00000001021 0.64995
183 1TU3 GNP 0.0000000005513 0.64993
184 4K81 GTP 0.0000000008752 0.64947
185 1M2O GNP 0.0000000003095 0.64881
186 1M2O GNP 0.0000000003095 0.64881
187 3WXM GTP 0.0000000001894 0.64864
188 1UPT GTP 0.00000000001835 0.64851
189 4KVG GTP 0.0000000003724 0.64776
190 4LPS GDP 0.0000002248 0.64764
191 2UZI GTP 0.0000000003851 0.64753
192 3VMF GTP 0.0000000003684 0.64664
193 1U8Z GDP 0.00000001894 0.64622
194 3PQC GDP 0.0000009249 0.64591
195 4LX0 BEF GDP 0.0000000004616 0.64471
196 3A1S GDP 0.000000259 0.64463
197 1UAD GNP 0.0000000002912 0.64305
198 3WXM GTP 0.0000000004783 0.64289
199 2D7C GTP 0.0000000008694 0.6425
200 4HI0 GDP 0.00000003542 0.64222
201 1LFD GNP 0.000000000574 0.64177
202 2BME GNP 0.0000000005632 0.64167
203 3BC1 GNP 0.0000000005947 0.64109
204 1HE1 AF3 0.000001525 0.64087
205 2GJ8 ALF GDP 0.000000005302 0.63968
206 2AWN ADP 0.000004212 0.63885
207 4V0K GDP 0.00000001252 0.63879
208 2HF9 GSP 0.00000009668 0.63878
209 3WXM GTP 0.0000000003969 0.63789
210 3WXM GTP 0.0000000006735 0.6375
211 1EK0 GNP 0.0000000007756 0.63666
212 1OIX GDP 0.000000001239 0.63664
213 3E5H GNP 0.000000000887 0.63595
214 3E5H GNP 0.000000000887 0.63595
215 4KVG GTP 0.0000000008967 0.63477
216 3LRE ADP 0.000003609 0.6346
217 3LRE ADP 0.000003609 0.6346
218 2BME GNP 0.0000000005399 0.63388
219 4C4P GNP 0.000000001528 0.63374
220 1TU3 GNP 0.0000000009543 0.63355
221 3LRE ADP 0.00000372 0.63317
222 4K81 GTP 0.000000001608 0.63265
223 4HDQ GNP 0.000000001703 0.63174
224 2D7C GTP 0.000000001062 0.63158
225 1MH1 GNP 0.000000002565 0.63151
226 1GOJ ADP 0.000004421 0.62977
227 2BME GNP 0.0000000007489 0.62952
228 4NCN GTP 0.0000000003714 0.62936
229 4NCN GTP 0.0000000004407 0.62699
230 1WQ1 GDP 0.0000000363 0.6267
231 3NKV GNP 0.000000001574 0.62629
232 1GRN GDP 0.0000002011 0.62423
233 1JJ7 ADP 0.000006135 0.62329
234 4LPS GDP 0.0000004922 0.62238
235 1V8K ANP 0.000001202 0.62076
236 1V8K ANP 0.000001202 0.62076
237 2HV8 GTP 0.000000002399 0.61934
238 1KMQ GNP 0.0000000008854 0.61855
239 1TQ4 GDP 0.0000001337 0.61691
240 1NF3 GNP 0.000000002883 0.61666
241 1NF3 GNP 0.000000001925 0.61621
242 3A1S GDP 0.0000009967 0.61604
243 2CBZ ATP 0.000008968 0.61551
244 1E96 GTP 0.000000003408 0.61484
245 1CXZ GSP 0.0000000006587 0.61455
246 1Z2A GDP 0.00000007151 0.61428
247 1HE1 AF3 0.000003893 0.61307
248 1NRJ GTP 0.0000000003756 0.61141
249 3LXR GDP 0.0000008612 0.61077
250 1G6H ADP 0.000009485 0.61033
251 2AWN ADP 0.000009866 0.60959
252 2FH5 GTP 0.0000000003951 0.60913
253 2FH5 GTP 0.0000000003951 0.60913
254 2FH5 GTP 0.0000000003951 0.60913
255 3REF GDP 0.0000001406 0.60877
256 1GWN GTP 0.0000000005397 0.60794
257 1S8F GDP 0.00000001153 0.60664
258 1S8F GDP 0.00000001153 0.60664
259 1S8F GDP 0.00000001153 0.60664
260 2W2X GSP 0.000000001155 0.60652
261 1WF3 GNP 0.000000007243 0.60621
262 1GWN GTP 0.0000000006183 0.60601
263 2BCG GDP 0.0000003455 0.60598
264 2EW1 GNP 0.000000002235 0.60557
265 2HV8 GTP 0.000000007468 0.60217
266 2F9L GDP 0.0000001425 0.60165
267 4DSU GDP 0.00000001448 0.59677
268 2W58 ADP 0.00001846 0.59469
269 2FJU GSP 0.0000000019 0.59298
270 1PUJ GNP 0.00000000007902 0.59201
271 1G3Q ADP 0.000003701 0.5882
272 4H1V GNP 0.000001268 0.58769
273 3T1O GDP 0.00000000004147 0.58578
274 3T1O GDP 0.00000000004606 0.58484
275 3KUD GDP 0.000000002802 0.58447
276 1YZG GDP 0.00000000001721 0.58351
277 2W2X GSP 0.000000003204 0.58285
278 3NKV GNP 0.000000005799 0.58244
279 1G4U GDP 0.00000118 0.5821
280 3RWO GDP 0.00000002793 0.57978
281 3RWO GDP 0.00000002793 0.57978
282 2NCD ADP 0.00002457 0.57755
283 4P4T GDP 0.000001504 0.57739
284 1HE1 GDP 0.000001272 0.57398
285 1XTQ GDP 0.00000001797 0.57325
286 3WYA GDP 0.00000000001218 0.57177
287 4NON GDP 0.0000001913 0.57175
288 3PQC GDP 0.000006385 0.56923
289 4BQS ADP 0.00002784 0.56812
290 3REF GDP 0.000001306 0.56713
291 1HE1 GDP 0.000001901 0.56633
292 1X1R GDP 0.0000000987 0.56591
293 3B9Q MLI 0.00003866 0.56521
294 2IYL GDP 0.0000188 0.56101
295 3Q9L ATP 0.00001413 0.55977
296 1MKY GDP 0.00000000005319 0.5596
297 2GCO GNP 0.000000007966 0.55955
298 2GCO GNP 0.000000004046 0.55951
299 1MR3 G3D 0.0000000001732 0.55782
300 3Q9L ATP 0.00001624 0.55682
301 1G4U AF3 0.00005779 0.55671
302 3T34 GDP 0.000001678 0.55646
303 1KAO GDP 0.000000005411 0.55295
304 2HF9 GSP 0.000001128 0.55221
305 2ZFI ADP 0.00002965 0.55111
306 3NHB ADP 0.00007932 0.55047
307 3DEF GDP 0.00001348 0.54706
308 1RE0 GDP 0.00000000002648 0.54674
309 4AG5 ADP 0.00009333 0.54565
310 4CVN ADP 0.00008166 0.54353
311 4CVN ADP 0.00008333 0.54306
312 1JI0 ATP 0.00008944 0.54145
313 4CVN ADP 0.00009267 0.54064
314 2WJH GDP 0.000000001126 0.54063
315 1S8F GDP 0.000000003016 0.5405
316 1S8F GDP 0.000000003016 0.5405
317 3Q85 GNP 0.0000000003835 0.54047
318 3B5J 12D 0.00009665 0.53968
319 1D2E GDP 0.000000005595 0.53962
320 1RYH GNP 0.00000000494 0.53855
321 1FZQ GDP 0.0000000004374 0.53773
322 4AG5 ADP 0.0001313 0.53745
323 2WMO GTP 0.0000000062 0.53678
324 4U5X GNP 0.00000004001 0.53611
325 4P3Y GDP 0.0000000001415 0.53569
326 1DAR GDP 0.0000000004728 0.53438
327 2ZEJ GDP 0.0000006332 0.53379
328 1KK1 GNP 0.000000000223 0.53289
329 1F6B GDP 0.000000001692 0.53274
330 3CH5 GDP 0.000000003286 0.53232
331 3CH5 GDP 0.000000003286 0.53232
332 1D8T GDP 0.000000000667 0.53175
333 4BQS ADP 0.00007293 0.53156
334 1D8T GDP 0.0000000007065 0.53144
335 3GJ5 GDP 0.000000003721 0.53114
336 3RWO GDP 0.00000001728 0.53114
337 2OG2 MLI 0.0001904 0.53106
338 2A9K GDP 0.00000002884 0.53025
339 2HCJ GDP 0.0000000003338 0.52966
340 3SFV GDP 0.0000001194 0.52796
341 3EZ2 ADP 0.0001185 0.52779
342 4CVN ADP 0.0001222 0.5271
343 3GJ4 GDP 0.000000005786 0.52654
344 1FP6 ADP 0.00003754 0.52629
345 2EFE GNH 0.000000092 0.52549
346 2XTN GTP 0.0000108 0.52235
347 2HT6 GDP 0.0000000004471 0.52087
348 2HT6 GDP 0.0000000004737 0.52059
349 1D5C GDP 0.00000007554 0.51852
350 1VG1 GDP 0.000000008131 0.51733
351 3GJ5 GDP 0.000000004789 0.5167
352 3GJ3 GDP 0.000000004717 0.51668
353 2ZR9 DTP 0.0001461 0.51646
354 3Q9L ATP 0.00004592 0.51641
355 2GCN GDP 0.0000004617 0.51616
356 3Q85 GNP 0.000000003163 0.51601
357 1SQ5 ADP 0.0001164 0.51502
358 1SQ5 ADP 0.0001179 0.51475
359 1Z0A GDP 0.00000001865 0.51464
360 1FP6 ADP 0.00003829 0.51444
361 1A4R GDP 0.0000002539 0.51389
362 1SQ5 ADP 0.0001238 0.51372
363 1VG9 GDP 0.0000000548 0.51287
364 1P9B GDP 0.00005631 0.51236
365 1Z0A GDP 0.00000000362 0.51204
366 1VG0 GDP 0.00000006917 0.51169
367 1VG9 GDP 0.00000005979 0.51167
368 4WZA ACP 0.00004283 0.51134
369 4WZA ADP 0.00004283 0.51134
370 1Z0A GDP 0.00000002774 0.51101
371 1Z0A GDP 0.00000005404 0.51101
372 1Z0A GDP 0.00000005404 0.51101
373 1Z0A GDP 0.00000002774 0.51101
374 3GJ4 GDP 0.000000008965 0.51095
375 3T5G GDP 0.00000003396 0.5105
376 2C04 GCP 0.00006452 0.50966
377 1JWY GDP 0.00000005452 0.50945
378 1G16 GDP 0.0000006983 0.50937
379 1OW3 GDP 0.0000001584 0.50741
380 1KY3 GDP 0.00000009543 0.50683
381 1VG9 GDP 0.00000002588 0.50568
382 3Q72 GNP 0.00000001711 0.5056
383 1W7J ADP BEF 0.00007991 0.50541
384 1A4R GNH 0.0000003115 0.50518
385 1B7T ADP 0.0001415 0.50497
386 2GDJ ANP 0.0002512 0.50468
387 1VG9 GDP 0.00000002993 0.50466
388 2C04 GCP 0.00005179 0.50336
389 2RCN GDP 0.000000009355 0.50302
390 2RCN GDP 0.000000009355 0.50302
391 3Q72 GNP 0.000000004405 0.50175
392 1G6O ADP 0.0001661 0.50165
393 1G6O ADP 0.0001661 0.50165
394 3CPJ GDP 0.0000001865 0.50154
395 1Z0A GDP 0.00000001557 0.50108
396 1Z0F GDP 0.00000003222 0.50055
397 2NGR GDP 0.00000006168 0.50034
398 1KK8 BEF ADP 0.000105 0.5
399 3MD0 GDP 0.000000002995 0.49983
400 3EC1 GDP 0.00000004119 0.4998
401 1QF5 GDP 0.00004976 0.49956
402 1QF5 RPL 0.00004976 0.49956
403 4HSE ADP 0.0002619 0.49782
404 2FNA ADP 0.0000546 0.4974
405 3EC1 GDP 0.000000008068 0.49737
406 4IDN GNP 0.00002328 0.4943
407 2WJH FLC 0.00000009464 0.49426
408 2EFE GNH 0.0000003284 0.49383
409 1IWE IMP 0.0003536 0.49364
410 3ZS9 ADP ALF 0.00002536 0.49282
411 1F5N GNP 0.00002689 0.49181
412 2FNA ADP 0.00005911 0.4912
413 1CLU DBG 0.0000001945 0.49105
414 3ZS9 ADP ALF 0.00005157 0.48913
415 2DPY ADP 0.001008 0.48608
416 3TK1 GDP 0.000000008608 0.48521
417 2B8W ALF 5GP 0.000006738 0.48518
418 3FKQ ATP 0.0002398 0.4836
419 2B8W ALF 5GP 0.000008225 0.48219
420 3ZQ6 ADP ALF 0.00001554 0.48202
421 2VB6 ADP BEF 0.000126 0.48178
422 3ZQ6 ADP ALF 0.00002282 0.48115
423 4IEE AGS 0.001096 0.47822
424 3VX3 ADP 0.0002689 0.47654
425 4D0N GDP 0.0000001383 0.47648
426 4ITR GDP 0.000002556 0.47623
427 1YTM ATP 0.0002239 0.47546
428 3ZFD ANP 0.0000004624 0.47515
429 1DS6 GDP 0.0000001688 0.47505
430 2PL3 ADP 0.0013 0.47442
431 4DID GDP 0.0000003915 0.47379
432 3KTA AP5 0.000504 0.4736
433 1YTM ATP 0.0002663 0.47216
434 2BEK ATP 0.0002154 0.47176
435 2WOJ ADP ALF 0.00002995 0.47144
436 2WOJ ADP ALF 0.00003003 0.47139
437 2NGR AF3 0.00000001997 0.47112
438 1SVI GDP 0.000000167 0.46812
439 3HU3 AGS 0.0003356 0.46775
440 4QOS ADP 0.0008731 0.46722
441 2J0V GDP 0.0000009051 0.46531
442 2J0V GDP 0.0000009682 0.46476
443 2J0V GDP 0.0000009971 0.46392
444 1I4D GDP 0.0000002716 0.46391
445 1OYY AGS 0.001655 0.4637
446 2OBM ADP 0.003373 0.46326
447 2C9O ADP 0.0004257 0.46322
448 2J0V GDP 0.000001175 0.46314
449 1Z6T ADP 0.0007849 0.46005
450 1Z6T ADP 0.0007893 0.45993
451 1Z6T ADP 0.0007994 0.45968
452 4OHY ANP 0.0002696 0.45939
453 1FNN ADP 0.0006492 0.45939
454 1FNN ADP 0.0007413 0.45681
455 1A5Z FBP 0.004479 0.45335
456 3FVQ ATP 0.0007546 0.45231
457 2C9O ADP 0.0007899 0.45144
458 2CK3 ANP 0.001081 0.44948
459 1Z6T ADP 0.001121 0.44877
460 3BFX A3P 0.001276 0.44624
461 1OW3 MGF 0.0000002385 0.44615
462 1IHU ADP 0.00005616 0.44596
463 3LDJ SCR 0.01029 0.44552
464 4A4Z ANP 0.003831 0.44544
465 1GXU 2HP 0.00308 0.44535
466 3B7G ANP 0.003105 0.44532
467 2ZTS ADP 0.001377 0.44477
468 1H65 GDP 0.00005381 0.44442
469 1IHU AF3 0.00004458 0.4438
470 3B7G ANP 0.00348 0.44289
471 3FWY ADP 0.00001447 0.44246
472 3KTA AP5 0.001339 0.44138
473 1W5T ADP 0.002055 0.44092
474 1G8S MET 0.008276 0.44
475 1ZUI SKM 0.0006955 0.43761
476 1B0U ATP 0.002988 0.43748
477 1H65 GDP 0.00008732 0.43712
478 1W5T ANP 0.001768 0.43608
479 2Q2Y MKR 0.004298 0.43547
480 2Q2Y ADP 0.004298 0.43547
481 2GWH A3P 0.00271 0.43542
482 1W5T ANP 0.001865 0.43505
483 3IO3 ADP 0.000007656 0.43484
484 3IO3 ADP 0.00003439 0.43419
485 1BO4 COA 0.006686 0.43331
486 2J5V PCA 0.01529 0.43217
487 1ION ADP 0.00001011 0.43154
488 2OFW ADX 0.001287 0.43066
489 3W5J GDP 0.00000007718 0.43012
490 1QHH ATP 0.006379 0.43
491 4JLN 18V 0.01805 0.42914
492 4JLN UDP 0.01805 0.42914
493 1L2T ATP 0.001499 0.42853
494 1L2T ATP 0.001499 0.42853
495 1M7G ADX 0.0008664 0.42833
496 3E70 GDP 0.00001461 0.42765
497 1UPR 4IP 0.02095 0.42763
498 2QEN ADP 0.00003765 0.42725
499 2CK3 ADP 0.001942 0.4272
500 1E4V AP5 0.002147 0.42707
501 1E4V AP5 0.002296 0.42687
502 4GOX A3P 0.00204 0.42629
503 3R7F CP 0.01589 0.42481
504 1M7G ADX 0.001106 0.4242
505 1M7G ADX 0.001106 0.4242
506 1M7G ADX 0.001106 0.4242
507 1M7G ADX 0.001106 0.4242
508 1X6V ADP 0.0009286 0.42414
509 2PEZ GGZ 0.001238 0.4237
510 2PEZ DAT 0.001238 0.4237
511 3QOX SAH 0.0004075 0.42351
512 1K6M AGS 0.003004 0.42251
513 2VOH CIT 0.01483 0.42249
514 4E03 ADP 0.00002166 0.42234
515 4E03 ADP 0.00002166 0.42234
516 1YBH P22 0.01207 0.42042
517 1YBH P22 0.01207 0.42042
518 2F5X ASP 0.02026 0.41885
519 1K6M AGS 0.003083 0.41872
520 4WLB TLA 0.02792 0.41775
521 4WLB TLA 0.02792 0.41775
522 4WLB TLA 0.02792 0.41775
523 1T0S BML 0.02052 0.41739
524 1T0S BML 0.02052 0.41739
525 3KJI ADP 0.00009994 0.41724
526 3KJI ADP 0.0001104 0.41693
527 1QXA GLY GLY GLY 0.02604 0.41631
528 1I0B PEL 0.01323 0.4151
529 2V26 ADP 0.0002975 0.41433
530 4IOK ADP 0.001391 0.41377
531 3MBI HSX 0.01971 0.41367
532 2BIF SIN 0.004351 0.41356
533 2BIF ANP 0.002429 0.41356
534 1M7G AV2 0.000006565 0.41354
535 3W6G FLC 0.02565 0.41301
536 1W0J ADP 0.00006374 0.41291
537 1M7G AV2 0.000006585 0.41263
538 1M7G AV2 0.00002256 0.41263
539 1M7G AV2 0.000006585 0.41263
540 1M7G AV2 0.000006585 0.41263
541 4MUB A3P 0.007175 0.41261
542 4MUB A3P 0.007175 0.41261
543 1M7G ADP 0.001858 0.41252
544 1UJ2 C5P 0.00109 0.41251
545 3FB4 AP5 0.003952 0.41219
546 3UJS 0V5 0.01243 0.41201
547 1M7G ADP 0.001928 0.41191
548 1Y63 ADP 0.00001258 0.41182
549 3VM7 GLC 0.01788 0.41121
550 3ZIA ADP 0.00007995 0.41108
551 4MKG AP5 0.004219 0.41104
552 3ZIA ADP 0.0000801 0.41102
553 1U2Z SAH 0.0008965 0.41102
554 1NJF AGS 0.0004336 0.41081
555 2Q2Y MKR 0.004173 0.41016
556 2Q2Y ADP 0.004437 0.41016
557 2PW0 TRC 0.02335 0.40986
558 2PW0 TRC 0.02335 0.40986
559 2PW0 TRC 0.02335 0.40986
560 4IOK XPO 0.0008794 0.40951
561 4GBM A3P 0.005122 0.4094
562 1U2Z SAH 0.0009903 0.40938
563 4OEV OXL 0.02994 0.4087
564 1NJF AGS 0.0003702 0.40868
565 1S3G AP5 0.004885 0.40847
566 3UJS XSP 0.01251 0.40832
567 4MKF AP5 0.005366 0.40786
568 1U2Z SAH 0.0008701 0.40777
569 3BD9 A3P 0.01839 0.40741
570 2V7Q ATP 0.00005843 0.4072
571 1OS1 ATP 0.0026 0.4069
572 2QQC AG2 0.03381 0.40673
573 2CHG ANP 0.0003255 0.40665
574 2DWO ADP 0.004518 0.40654
575 2F5X ASP 0.03225 0.40654
576 4JD0 1KH 0.03382 0.40635
577 1OS1 PYR 0.002985 0.40602
578 4OEV OXL 0.03354 0.40592
579 1NJF AGS 0.0006024 0.40583
580 3W6G FLC 0.03333 0.40578
581 4E03 ADP 0.00002034 0.40574
582 4OI4 ATP 0.0007659 0.40512
583 2F5X ASP 0.03446 0.405
584 2CHG ANP 0.0007048 0.40488
585 1LVG ADP 0.000004246 0.40461
586 4OI4 ATP 0.0007825 0.40455
587 1RJ9 GCP 0.00007868 0.40455
588 4MKF AP5 0.005776 0.40448
589 3ZIA ATP 0.00004419 0.4043
590 3ZIA ATP 0.00004451 0.40423
591 3QXC ATP 0.004307 0.40378
592 1WZU MLT 0.03707 0.4033
593 1QF9 ADP 0.005509 0.40311
594 1QF9 C5P 0.005509 0.40311
595 1QF9 ALF 0.005509 0.40311
596 2QQD AG2 0.03749 0.40304
597 2CHG ANP 0.0004317 0.403
598 2DWO PEP 0.00524 0.40283
599 2FAH GDP 0.0002774 0.40268
600 1JWY ADP 0.00004664 0.40246
601 3VSV XYS 0.04055 0.40233
602 4M6T SAM 0.0447 0.40219
603 3FYH ADP 0.006536 0.40201
604 3DC4 ADP 0.000009531 0.40176
605 2CE7 ADP 0.0001092 0.40145
606 2FAH GDP 0.0002064 0.40144
607 2FAH GDP 0.0003117 0.40119
608 3BOS CDP 0.00003745 0.40082
609 1NJF ADP 0.0004432 0.40078
610 2OH5 CTP 0.04894 0.40056
611 2OH5 CTP 0.04894 0.40056
612 2OH5 CTP 0.04894 0.40056
613 4ADM SRT 0.03546 0.40041
614 2FAH GDP 0.0002355 0.40019
615 2RGX AP5 0.008818 0.4001
Pocket No.: 2; Query (leader) PDB : 1AZT; Ligand: GSP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 1azt.bio1) has 28 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc)
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