Receptor
PDB id Resolution Class Description Source Keywords
1BH2 2.1 Å NON-ENZYME: SIGNAL_HORMONE A326S MUTANT OF AN INHIBITORY ALPHA SUBUNIT RATTUS NORVEGICUS SIGNAL TRANSDUCTION PROTEIN
Ref.: THE A326S MUTANT OF GIALPHA1 AS AN APPROXIMATION OF THE RECEPTOR-BOUND STATE. J.BIOL.CHEM. V. 273 21752 1998
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GSP A:355;
Valid;
none;
submit data
539.246 C10 H16 N5 O13 P3 S c1nc2...
MG A:357;
Part of Protein;
none;
submit data
24.305 Mg [Mg+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1BH2 2.1 Å NON-ENZYME: SIGNAL_HORMONE A326S MUTANT OF AN INHIBITORY ALPHA SUBUNIT RATTUS NORVEGICUS SIGNAL TRANSDUCTION PROTEIN
Ref.: THE A326S MUTANT OF GIALPHA1 AS AN APPROXIMATION OF THE RECEPTOR-BOUND STATE. J.BIOL.CHEM. V. 273 21752 1998
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 224 families.
1 1BH2 - GSP C10 H16 N5 O13 P3 S c1nc2c(n1C....
70% Homology Family (21)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 1GFI - ALF GDP n/a n/a
2 4N0E - GDP C10 H15 N5 O11 P2 c1nc2c(n1C....
3 4PAM - GDP C10 H15 N5 O11 P2 c1nc2c(n1C....
4 1AS0 - GSP C10 H16 N5 O13 P3 S c1nc2c(n1C....
5 1GIL - GSP C10 H16 N5 O13 P3 S c1nc2c(n1C....
6 3FFA Kd = 0.69 uM GSP C10 H16 N5 O13 P3 S c1nc2c(n1C....
7 1GDD - GDP C10 H15 N5 O11 P2 c1nc2c(n1C....
8 4PAO - GSP C10 H16 N5 O13 P3 S c1nc2c(n1C....
9 1BOF - GDP C10 H15 N5 O11 P2 c1nc2c(n1C....
10 1CIP - GNP C10 H17 N6 O13 P3 c1nc2c(n1C....
11 1GIA - GSP C10 H16 N5 O13 P3 S c1nc2c(n1C....
12 4N0D - GSP C10 H16 N5 O13 P3 S c1nc2c(n1C....
13 1AS3 - GDP C10 H15 N5 O11 P2 c1nc2c(n1C....
14 1SVS Kd = 2.3 nM GNP C10 H17 N6 O13 P3 c1nc2c(n1C....
15 1SVK Kd = 1.1 nM ALF GDP n/a n/a
16 4PAN - GDP C10 H15 N5 O11 P2 c1nc2c(n1C....
17 4PAQ - GSP C10 H16 N5 O13 P3 S c1nc2c(n1C....
18 1TAG - GDP C10 H15 N5 O11 P2 c1nc2c(n1C....
19 1TND - GSP C10 H16 N5 O13 P3 S c1nc2c(n1C....
20 1TAD - GDP C10 H15 N5 O11 P2 c1nc2c(n1C....
21 1BH2 - GSP C10 H16 N5 O13 P3 S c1nc2c(n1C....
50% Homology Family (24)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 1GFI - ALF GDP n/a n/a
2 4N0E - GDP C10 H15 N5 O11 P2 c1nc2c(n1C....
3 4PAM - GDP C10 H15 N5 O11 P2 c1nc2c(n1C....
4 1AS0 - GSP C10 H16 N5 O13 P3 S c1nc2c(n1C....
5 1GIL - GSP C10 H16 N5 O13 P3 S c1nc2c(n1C....
6 3FFA Kd = 0.69 uM GSP C10 H16 N5 O13 P3 S c1nc2c(n1C....
7 1GDD - GDP C10 H15 N5 O11 P2 c1nc2c(n1C....
8 4PAO - GSP C10 H16 N5 O13 P3 S c1nc2c(n1C....
9 1BOF - GDP C10 H15 N5 O11 P2 c1nc2c(n1C....
10 1CIP - GNP C10 H17 N6 O13 P3 c1nc2c(n1C....
11 1GIA - GSP C10 H16 N5 O13 P3 S c1nc2c(n1C....
12 4N0D - GSP C10 H16 N5 O13 P3 S c1nc2c(n1C....
13 1AS3 - GDP C10 H15 N5 O11 P2 c1nc2c(n1C....
14 1SVS Kd = 2.3 nM GNP C10 H17 N6 O13 P3 c1nc2c(n1C....
15 1SVK Kd = 1.1 nM ALF GDP n/a n/a
16 4PAN - GDP C10 H15 N5 O11 P2 c1nc2c(n1C....
17 4PAQ - GSP C10 H16 N5 O13 P3 S c1nc2c(n1C....
18 1TAG - GDP C10 H15 N5 O11 P2 c1nc2c(n1C....
19 1TND - GSP C10 H16 N5 O13 P3 S c1nc2c(n1C....
20 1TAD - GDP C10 H15 N5 O11 P2 c1nc2c(n1C....
21 1AZT - GSP C10 H16 N5 O13 P3 S c1nc2c(n1C....
22 1BH2 - GSP C10 H16 N5 O13 P3 S c1nc2c(n1C....
23 2XTZ - GSP C10 H16 N5 O13 P3 S c1nc2c(n1C....
24 1ZCB - GDP C10 H15 N5 O11 P2 c1nc2c(n1C....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GSP; Similar ligands found: 120
No: Ligand ECFP6 Tc MDL keys Tc
1 GSP 1 1
2 GP3 0.897436 0.925
3 GTP 0.853659 0.948718
4 GNH 0.829268 0.936709
5 GDP 0.817073 0.948718
6 G1R 0.8 0.936709
7 GCP 0.77907 0.925
8 GNP 0.770115 0.925
9 GMV 0.767442 0.925
10 G 0.756098 0.935897
11 5GP 0.756098 0.935897
12 G2R 0.747253 0.91358
13 GDD 0.744681 0.91358
14 GKE 0.744681 0.91358
15 GDC 0.744681 0.91358
16 GPG 0.73913 0.91358
17 GTG 0.736842 0.891566
18 G3A 0.729167 0.925
19 G5P 0.721649 0.925
20 GFB 0.71875 0.91358
21 GDR 0.71875 0.91358
22 GAV 0.714286 0.987179
23 GP2 0.712644 0.91358
24 Y9Z 0.708333 0.860465
25 JB2 0.69697 0.91358
26 GKD 0.69697 0.91358
27 GDP MG 0.696629 0.878049
28 G2P 0.692308 0.91358
29 GPD 0.69 0.880952
30 GDX 0.69 0.925
31 GCP G 0.677419 0.888889
32 ALF 5GP 0.67033 0.847059
33 0O2 0.666667 0.935897
34 GTP MG 0.666667 0.878049
35 BEF GDP 0.666667 0.847059
36 YGP 0.663265 0.858824
37 JB3 0.657143 0.902439
38 GDP AF3 0.645833 0.847059
39 GDP ALF 0.645833 0.847059
40 GMP 0.641975 0.835443
41 G3D 0.638298 0.935897
42 NGD 0.635514 0.91358
43 2MD 0.633027 0.894118
44 CAG 0.630631 0.840909
45 G4P 0.625 0.935897
46 FEG 0.62037 0.83908
47 U2G 0.62037 0.891566
48 G G 0.617647 0.901235
49 MGD 0.616071 0.894118
50 CG2 0.609091 0.891566
51 TPG 0.598291 0.804348
52 3GP 0.595506 0.898734
53 GDP 7MG 0.590476 0.86747
54 MD1 0.581197 0.894118
55 PGD 0.581197 0.926829
56 2GP 0.577778 0.911392
57 DGT 0.561224 0.878049
58 DBG 0.558333 0.902439
59 G1G 0.550847 0.880952
60 SAP 0.547368 0.924051
61 AGS 0.547368 0.924051
62 FE9 0.546219 0.8
63 G4M 0.539062 0.840909
64 G A A A 0.529915 0.878049
65 MGP 0.525253 0.91358
66 GPX 0.524272 0.898734
67 BGO 0.521739 0.879518
68 DGI 0.520408 0.878049
69 I2C FE2 CMO CMO 0.516667 0.774194
70 IDP 0.515464 0.923077
71 GGM 0.508475 0.858824
72 G1R G1R 0.508065 0.879518
73 PGD O 0.504 0.875
74 G G U 0.5 0.888889
75 GTA 0.486726 0.891566
76 P2G 0.484536 0.839506
77 GPC 0.483607 0.83908
78 G C 0.483333 0.857143
79 P1G 0.474747 0.829268
80 DGP 0.474227 0.865854
81 DG 0.474227 0.865854
82 BA3 0.46875 0.85
83 IMP 0.463918 0.910256
84 B4P 0.463918 0.85
85 AP5 0.463918 0.85
86 G2Q 0.462963 0.91358
87 G G G RPC 0.459016 0.833333
88 U G A 0.452555 0.847059
89 ATP 0.45 0.873418
90 G G G C 0.448819 0.869048
91 A2D 0.447917 0.85
92 AQP 0.445545 0.873418
93 5FA 0.445545 0.873418
94 G7M 0.444444 0.901235
95 G U34 0.442623 0.847059
96 01G 0.442478 0.860465
97 ITT 0.44 0.825
98 SGP 0.44 0.876543
99 G C C C 0.431818 0.879518
100 DG DG 0.428571 0.825581
101 A4P 0.42623 0.829545
102 PCG 0.423077 0.886076
103 35G 0.423077 0.886076
104 C2E 0.423077 0.875
105 MGO 0.420561 0.823529
106 ADP 0.42 0.873418
107 ANP 0.419048 0.851852
108 5GP 5GP 0.419048 0.839506
109 ADQ 0.418182 0.829268
110 APR 0.417476 0.85
111 AR6 0.417476 0.85
112 AD9 0.413462 0.851852
113 UP5 0.413223 0.831325
114 A22 0.412844 0.8625
115 25L 0.412281 0.8625
116 M33 0.411765 0.839506
117 JBT 0.410405 0.783505
118 ACP 0.407767 0.851852
119 ACQ 0.40566 0.851852
120 A1R 0.405405 0.8
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1BH2; Ligand: GSP; Similar sites found: 601
This union binding pocket(no: 1) in the query (biounit: 1bh2.bio1) has 29 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc)
1 1FQJ GDP 0.000000000000001554 0.95077
2 1FQJ GDP 0.00000000000000111 0.94435
3 1FQK GDP 0.00000000000000111 0.94341
4 1FQK GDP 0.000000000000001443 0.93838
5 1FQK ALF 0.0000000000128 0.93135
6 1CS4 GSP 2.576e-16 0.91955
7 1FQJ ALF 0.00000000001191 0.91788
8 1GOT GDP 0.00000000000001066 0.91511
9 3CX8 GSP 2.418e-16 0.90901
10 1FQJ ALF 0.00000000001986 0.90545
11 1FQK ALF 0.00000000002238 0.90257
12 3T12 GDP ALF 0.0000000000003502 0.8498
13 2WIC GNP 0.00000000002348 0.84215
14 2WIC GNP 0.00000000002348 0.84215
15 3AQ4 GDP 0.00000000003149 0.83592
16 2ODE ALF GDP 0.000000000000002331 0.83534
17 3WYA GDP 0.00000000006416 0.83453
18 3N5C GDP 0.00000000006922 0.83288
19 3AQ4 GDP 0.00000000003878 0.8315
20 1S9D GDP 0.00000000003997 0.83086
21 3N5C GDP 0.00000000004747 0.82721
22 1GP2 GDP 0.0000000000007201 0.8251
23 1SKQ GDP 0.0000000001913 0.82479
24 2OM2 GDP 0.000000000004407 0.81354
25 1ZJ6 G3D 0.000000000104 0.81058
26 1ZJ6 G3D 0.000000000104 0.81058
27 1ZJ6 G3D 0.000000000104 0.81058
28 2W83 GTP 0.00000000000233 0.80358
29 2J59 GTP 0.000000000005289 0.79908
30 2WJG GDP 0.0000000003344 0.79866
31 3WY9 GDP 0.0000000006424 0.79782
32 3WY9 GDP 0.0000000006504 0.79754
33 2J59 GTP 0.000000000003271 0.79737
34 1O3Y GTP 0.000000000003327 0.79706
35 2WJG GDP 0.0000000006692 0.79691
36 2J59 GTP 0.000000000003541 0.79592
37 2J59 GTP 0.000000000004211 0.79274
38 3PCR GTP 0.000000000004502 0.79152
39 2J59 GTP 0.000000000005349 0.78836
40 2J59 GTP 0.000000000005389 0.78822
41 4B47 GDP 0.0000000009921 0.78814
42 2OM2 GDP 0.00000000001015 0.7869
43 4M9Q GNP 0.00000000001047 0.78633
44 4J0Q GDP 0.000000001106 0.78571
45 2QN6 GDP 0.000000001176 0.78435
46 4J0Q GDP 0.000000001212 0.78368
47 4M9Q GNP 0.00000000001239 0.78318
48 4M9Q GNP 0.00000000001266 0.78278
49 4J0Q GDP 0.000000001383 0.78073
50 4J0Q GDP 0.000000001547 0.77825
51 1SKQ GDP 0.0000000004787 0.77817
52 3CNL GNP 0.000000001572 0.77788
53 3U6B GDP 0.000000001775 0.77518
54 3U6B GDP 0.000000002342 0.76901
55 3DOE GTP 0.00000000001588 0.76842
56 4J0Q GDP 0.000000002451 0.768
57 1O3Y GTP 0.00000000001234 0.76324
58 4NON GDP 0.000000001988 0.75992
59 2CJW GDP 0.000000002853 0.75207
60 1J2J GTP 0.00000000004695 0.74856
61 3MD0 GDP 0.00000001008 0.7365
62 4G5G GDP 0.00000000619 0.73524
63 1WQ1 AF3 0.00000004471 0.73183
64 3U6K GDP 0.000000007317 0.73161
65 1WDT GTP 0.0000000005523 0.73117
66 1F6B GDP 0.000000004699 0.72971
67 2C78 GNP 0.000000000227 0.72886
68 2A5F GTP 0.0000000000009768 0.72805
69 1G7S GDP 0.000000005355 0.72694
70 2BVN GNP 0.000000002043 0.72547
71 4DKX GDP 0.00000001004 0.72475
72 2BVN GNP 0.000000002189 0.72406
73 3AB3 GDP 0.00000000000008937 0.72077
74 3U6K GDP 0.00000001456 0.71666
75 3AB3 GDP 0.0000000000001347 0.71527
76 1A2K GDP 0.00000001143 0.71085
77 1A2K GDP 0.00000001143 0.71085
78 3GJ8 GDP 0.00000001401 0.70653
79 3GJ7 GDP 0.00000001411 0.70637
80 2Y8E GNP 0.0000000001936 0.70524
81 2Y8E GNP 0.0000000001936 0.70524
82 3GJ8 GDP 0.00000001493 0.70518
83 1S8F GDP 0.000000009768 0.70367
84 1S8F GDP 0.000000009768 0.70367
85 3TK1 GDP 0.00000007449 0.70347
86 3GJ7 GDP 0.00000002718 0.70309
87 4DKX GDP 0.00000001761 0.70167
88 1A2K GDP 0.00000004825 0.70163
89 3W5J GDP 0.0000001564 0.69889
90 2Y8E GNP 0.0000000002999 0.69751
91 1IBR GNP 0.0000000001951 0.69692
92 1IBR GNP 0.0000000002018 0.69634
93 4KAX GTP 0.000000000001788 0.69599
94 4BAS GNP 0.000000000001901 0.69363
95 4BAS GNP 0.000000000001901 0.69363
96 3GJ0 GDP 0.00000004248 0.69339
97 1Z0K GTP 0.000000000963 0.69321
98 3GJ4 GDP 0.00000004391 0.69268
99 3GJ4 GDP 0.00000002715 0.69249
100 1GRN AF3 0.0000001509 0.68733
101 1ZD9 GDP 0.000000005369 0.68695
102 3WYG GTP 0.0000000002417 0.68539
103 4LHW GNP 0.00000000107 0.68301
104 1R4A GNP 0.00000000002063 0.68225
105 4V0K GDP 0.000000006965 0.68189
106 1YZK GNP 0.000000001182 0.68122
107 3TH5 GNP 0.000000007685 0.67998
108 4TMZ GSP 0.000000002184 0.6782
109 1D2E GDP 0.00000002122 0.67799
110 4TMZ GSP 0.000000002256 0.67761
111 2X77 GDP 0.00000005506 0.67749
112 2G77 AF3 0.0000003426 0.67646
113 4HAT GNP 0.0000000001765 0.67554
114 3DDC GNP 0.000000000693 0.67495
115 3DDC GNP 0.000000000693 0.67495
116 3QBT GNP 0.000000001122 0.67423
117 3QBT GNP 0.000000001127 0.67415
118 4HDO GNP 0.0000000007443 0.67371
119 1Z08 GNP 0.0000000008293 0.67184
120 2C5L GTP 0.0000000008322 0.67178
121 1Z0K GTP 0.000000003134 0.67158
122 1Z08 GNP 0.000000001304 0.67158
123 1G7C 5GP 0.0000001179 0.67121
124 3QBT GNP 0.000000001353 0.67093
125 3KUD GDP 0.000000008385 0.66967
126 2C5L GTP 0.0000000009603 0.6693
127 2G77 GDP 0.0000000208 0.66928
128 1TX4 ALF GDP 0.000000003625 0.66892
129 3MJH GTP 0.000000001571 0.66828
130 2WMO GTP 0.00000005631 0.66734
131 2CL6 CAG 0.000000001714 0.66675
132 4GOJ GNP 0.00000000001579 0.66666
133 3TKL GTP 0.000000002751 0.66603
134 1EK0 GNP 0.000000001786 0.66602
135 4LHW GNP 0.00000000182 0.66569
136 1VG8 GNP 0.0000000002198 0.66412
137 3QBT GNP 0.000000001995 0.66407
138 1VG8 GNP 0.0000000002275 0.66355
139 1GUA GNP 0.000000001426 0.66244
140 1Z06 GNP 0.000000003425 0.66209
141 2AWN ADP 0.000002295 0.66159
142 4DCT GDP 0.0000001195 0.66105
143 1Z0F GDP 0.00000012 0.66096
144 3WYF GTP 0.0000000004062 0.66083
145 1NF3 GNP 0.000000004032 0.65916
146 4LPS GDP 0.0000001329 0.65879
147 2FFQ GSP 0.0000000003289 0.65825
148 1VG8 GNP 0.0000000003252 0.65801
149 4LHW GNP 0.000000002853 0.65776
150 1VG8 GNP 0.0000000003331 0.65758
151 4LHW GNP 0.000000002891 0.65752
152 3WYF GTP 0.0000000005763 0.65635
153 2HF9 GSP 0.00000004355 0.65461
154 1YZN GNP 0.000000002289 0.65424
155 2WKQ GTP 0.000000008089 0.65421
156 1UPT GTP 0.00000000003324 0.65333
157 1NVU GTP 0.0000000004974 0.65147
158 1NVU GTP 0.0000000004974 0.65147
159 2A5J GDP 0.000000123 0.65114
160 1YZQ GNP 0.0000000005227 0.65044
161 3GJX GTP 0.0000000005393 0.65021
162 3GJ0 GDP 0.0000000836 0.65017
163 1NVV GNP 0.0000000005391 0.65
164 1NVV GNP 0.0000000005391 0.65
165 1NVV GNP 0.0000000005391 0.65
166 1NVV GNP 0.0000000005391 0.65
167 3GJX GTP 0.0000000005489 0.64991
168 4LHW GNP 0.00000000455 0.64952
169 3TH5 GNP 0.00000008694 0.64938
170 1M2O GNP 0.000000000167 0.64904
171 4GOJ GNP 0.00000000002561 0.64811
172 3MJH GTP 0.000000003328 0.64775
173 1NF3 GNP 0.000000005078 0.64758
174 3NKV GNP 0.00000000508 0.64757
175 1YRB GDP 0.00000009863 0.64682
176 1WA5 GTP 0.0000000004612 0.64567
177 2QTV GNP 0.0000000002294 0.64448
178 1JWY GDP 0.0000001305 0.64113
179 1TU3 GNP 0.00000000148 0.64084
180 1KSH GDP 0.00000000005134 0.63991
181 1LFD GNP 0.0000000006585 0.63952
182 1UPT GTP 0.0000000000425 0.63827
183 1YVD GNP 0.000000008632 0.63821
184 3TNF GNP 0.000000001766 0.6381
185 2C77 GNP 0.00000000005154 0.63707
186 2BME GNP 0.0000000007921 0.63623
187 4LPS GDP 0.000000261 0.63553
188 1Z0J GTP 0.000000007121 0.63457
189 3WXM GTP 0.0000000004816 0.63428
190 1Z08 GNP 0.00000002416 0.63417
191 1UAD GNP 0.0000000009174 0.63385
192 3RAB GNP 0.0000000009605 0.6337
193 4LX0 BEF GDP 0.0000000009351 0.63359
194 3NKV GNP 0.00000004056 0.63199
195 2D7C GTP 0.000000001703 0.63158
196 2AWN ADP 0.000005592 0.63142
197 1G6H ADP 0.000004841 0.63141
198 1M2O GNP 0.000000001029 0.63065
199 1M2O GNP 0.000000001029 0.63065
200 4LC1 GDP 0.0000007651 0.63058
201 1JJ7 ADP 0.00000514 0.63041
202 1Z08 GNP 0.00000003003 0.63018
203 1Z08 GNP 0.00000003003 0.63018
204 3BC1 GNP 0.000000001185 0.62985
205 3VMF GTP 0.000000001139 0.62929
206 3WXM GTP 0.000000001206 0.62834
207 2W58 ADP 0.000006205 0.62712
208 4KVG GTP 0.000000001423 0.62698
209 4HI0 GDP 0.00000008368 0.62583
210 2BME GNP 0.000000001707 0.62472
211 4C4P GNP 0.000000002679 0.62469
212 1LFD GNP 0.00000000172 0.62468
213 1D5C GDP 0.0000001971 0.62463
214 2D7C GTP 0.000000001694 0.62391
215 1UAD GNP 0.000000001077 0.62354
216 2UZI GTP 0.000000001865 0.62346
217 2GJ8 ALF GDP 0.00000001396 0.6229
218 1TU3 GNP 0.000000003022 0.6229
219 3WXM GTP 0.000000001725 0.62277
220 1OIX GDP 0.000000003017 0.62247
221 2CBZ ATP 0.000006999 0.62216
222 3WXM GTP 0.000000001185 0.62121
223 3BC1 GNP 0.0000000022 0.62088
224 4KVG GTP 0.000000002241 0.62023
225 1V8K ANP 0.000001322 0.6187
226 1V8K ANP 0.000001322 0.6187
227 3A1S GDP 0.0000009046 0.61809
228 3PQC GDP 0.000003169 0.61777
229 4V0K GDP 0.00000004059 0.61764
230 3E5H GNP 0.000000002821 0.61735
231 3E5H GNP 0.000000002821 0.61735
232 1KMQ GNP 0.000000001268 0.61365
233 4HDQ GNP 0.00000000563 0.61263
234 2BME GNP 0.000000002278 0.61242
235 4NCN GTP 0.000000001229 0.6118
236 4NCN GTP 0.000000001373 0.61054
237 2HV8 GTP 0.000000004169 0.61047
238 2BME GNP 0.000000002647 0.6104
239 1CXZ GSP 0.000000000948 0.60956
240 1S8F GDP 0.00000002147 0.60899
241 1S8F GDP 0.00000002147 0.60899
242 1S8F GDP 0.00000002147 0.60899
243 2EFE GNH 0.0000002967 0.60894
244 1TU3 GNP 0.000000004679 0.60873
245 2GJ8 ALF GDP 0.00000003238 0.60832
246 1GRN GDP 0.0000004756 0.60715
247 4DID GDP 0.000001703 0.60466
248 1Z2A GDP 0.0000001221 0.60447
249 1GOJ ADP 0.000009255 0.60368
250 3A1S GDP 0.000001785 0.60367
251 1R2Q GNP 0.000000001211 0.60243
252 1TQ4 GDP 0.0000002885 0.60225
253 1WQ1 GDP 0.0000001431 0.60158
254 3LRE ADP 0.00001187 0.59913
255 2EFE GNH 0.000001039 0.59905
256 3LRE ADP 0.00001299 0.59683
257 3LRE ADP 0.00001299 0.59683
258 2W2X GSP 0.000000002959 0.59298
259 2HV8 GTP 0.00000001311 0.59277
260 1NRJ GTP 0.000000001429 0.59255
261 2F9L GDP 0.0000002494 0.59139
262 3DC4 ADP 0.00001077 0.58983
263 2EW1 GNP 0.000000006747 0.58967
264 2BCG GDP 0.0000009181 0.58698
265 3LXR GDP 0.000002774 0.58652
266 3T1O GDP 0.00000000004426 0.58579
267 3T1O GDP 0.00000000004934 0.58478
268 2XT3 ADP 0.00002123 0.58421
269 4DSU GDP 0.00000003963 0.58079
270 4H1V GNP 0.000001857 0.58011
271 1WF3 GNP 0.00000004396 0.57775
272 3REF GDP 0.0000007868 0.5766
273 1A4R GNH 0.000002352 0.57541
274 2FJU GSP 0.000000003522 0.57483
275 4BQS ADP 0.00002141 0.57412
276 3RWO GDP 0.00000004502 0.57221
277 3RWO GDP 0.00000004502 0.57221
278 1A4R GDP 0.000002303 0.56909
279 2W2X GSP 0.000000009832 0.56733
280 1Y63 ADP 0.00001481 0.56619
281 1YZG GDP 0.00000000007893 0.56616
282 2HF9 GSP 0.0000006612 0.56164
283 3T34 GDP 0.000001421 0.55951
284 2NCD ADP 0.00005252 0.55903
285 4P4T GDP 0.000004426 0.55639
286 3NHB ADP 0.0000631 0.55596
287 4NON GDP 0.0000005035 0.55527
288 3PQC GDP 0.00001382 0.55321
289 3B5J 12D 0.00006005 0.55055
290 3REF GDP 0.00000348 0.54882
291 1JI0 ATP 0.00006779 0.54778
292 1YQT ADP 0.00008956 0.54743
293 3Q9L ATP 0.00002567 0.5471
294 1MKY GDP 0.0000000001997 0.54639
295 3Q9L ATP 0.00002763 0.54554
296 1RE0 GDP 0.00000000004206 0.54277
297 3EZ2 ADP 0.00006264 0.54198
298 4AG5 ADP 0.0001114 0.54167
299 2IYL GDP 0.00004764 0.54081
300 2ZFI ADP 0.0000512 0.53924
301 2GCO GNP 0.00000004623 0.53771
302 4AG5 ADP 0.0001515 0.53402
303 2GCO GNP 0.00000003187 0.53349
304 4CVN ADP 0.0001269 0.53346
305 4CVN ADP 0.0001382 0.5315
306 4BQS ADP 0.00007412 0.5312
307 2WJH GDP 0.000000002953 0.5292
308 4CVN ADP 0.0001742 0.52622
309 2WHX ADP 0.0002195 0.52592
310 3DEF GDP 0.00003889 0.52557
311 3Q85 GNP 0.000000001872 0.52537
312 3UIE ANP 0.00009903 0.52491
313 4U5X GNP 0.0000001165 0.52391
314 2ZR9 DTP 0.0001038 0.52388
315 2ZEJ GDP 0.000001247 0.52313
316 1JWY ADP 0.00007963 0.52308
317 2V7Q ATP 0.00006956 0.5197
318 2QZ4 ADP 0.000072 0.51898
319 2A9K GDP 0.00000008009 0.51818
320 3RWO GDP 0.0000000442 0.51772
321 3SFV GDP 0.0000002888 0.51556
322 3GJ5 GDP 0.00000001562 0.51545
323 1DAR GDP 0.000000003607 0.51381
324 1KK1 GNP 0.000000002276 0.51161
325 4P3Y GDP 0.00000000197 0.51143
326 2HT6 GDP 0.000000001213 0.51112
327 1P9B GDP 0.00006157 0.51059
328 2HT6 GDP 0.00000000131 0.51052
329 1RYH GNP 0.00000006108 0.51045
330 1D8T GDP 0.000000006062 0.51037
331 4CVN ADP 0.0002611 0.51019
332 1D8T GDP 0.000000006444 0.50994
333 2HCJ GDP 0.000000003985 0.50654
334 1W7J ADP BEF 0.00007657 0.50626
335 2V7Q ADP 0.0002491 0.50486
336 1XP8 AGS 0.0003359 0.50457
337 3Q9L ATP 0.00008701 0.50372
338 1VG1 GDP 0.00000003528 0.50354
339 1Z0A GDP 0.00000005545 0.50352
340 3GJ5 GDP 0.00000001782 0.50286
341 4IEE AGS 0.0003649 0.50273
342 1VG9 GDP 0.0000001238 0.50262
343 3GJ3 GDP 0.00000001806 0.50249
344 1OW3 GDP 0.0000002075 0.50242
345 3T5G GDP 0.00000007114 0.50222
346 1VG9 GDP 0.0000001269 0.50207
347 3Q85 GNP 0.00000001335 0.50201
348 2XTN GTP 0.00003331 0.50171
349 3Q72 GNP 0.00000002447 0.50077
350 1Z0A GDP 0.0000001319 0.50072
351 1Z0A GDP 0.0000001319 0.50072
352 2GDJ ANP 0.000307 0.50032
353 1Z0A GDP 0.00000007364 0.50011
354 1Z0A GDP 0.00000007364 0.50011
355 1FP6 ADP 0.0001387 0.49978
356 1SQ5 ADP 0.000247 0.49906
357 1KK8 BEF ADP 0.0001105 0.49899
358 1SQ5 ADP 0.0002525 0.49859
359 2FNA ADP 0.00005196 0.49832
360 1VG0 GDP 0.0000002129 0.4976
361 3Q72 GNP 0.000000006136 0.49709
362 1SQ5 ADP 0.0002718 0.49703
363 2GCN GDP 0.000001903 0.49701
364 2RCN GDP 0.00000002288 0.4958
365 2RCN GDP 0.00000002288 0.4958
366 1FP6 ADP 0.0001016 0.49546
367 4WZA ADP 0.0001016 0.49541
368 4WZA ACP 0.0001016 0.49541
369 4HSE ADP 0.0002965 0.49518
370 1G6O ADP 0.0002336 0.49457
371 1G6O ADP 0.0002336 0.49457
372 1VG9 GDP 0.00000006288 0.49454
373 3UIE ANP 0.0002339 0.49454
374 1Z0A GDP 0.00000002295 0.4945
375 1Z0A GDP 0.00000002793 0.49406
376 2FNA ADP 0.00005271 0.4933
377 1VG9 GDP 0.00000008385 0.49226
378 3CPJ GDP 0.0000003737 0.49152
379 4IDN GNP 0.00002892 0.49054
380 2NGR GDP 0.0000001841 0.48839
381 3EC1 GDP 0.0000001233 0.4871
382 1B7T ADP 0.0003492 0.48623
383 1KY3 GDP 0.00000057 0.48569
384 1IHU AF3 0.0001047 0.48524
385 3EC1 GDP 0.00000002637 0.48464
386 2WJH FLC 0.0000002699 0.48382
387 2B8W ALF 5GP 0.00000751 0.48374
388 3DZD ADP 0.0003239 0.48257
389 3VX3 ADP 0.0002061 0.48171
390 2B8W ALF 5GP 0.000009185 0.48089
391 2BEK ATP 0.0001327 0.48081
392 2NGR AF3 0.000000005631 0.48063
393 3HU3 AGS 0.000172 0.48049
394 3FKQ ATP 0.0003006 0.47911
395 3ZS9 ADP ALF 0.00005661 0.4789
396 2VB6 ADP BEF 0.000151 0.47839
397 3RC3 ANP 0.001114 0.47787
398 1IHU ADP 0.0001296 0.47682
399 3ZS9 ADP ALF 0.0001036 0.47659
400 2WOJ ADP ALF 0.00006896 0.47548
401 1G41 ADP 0.0006122 0.47459
402 2WOJ ADP ALF 0.00007321 0.47444
403 1CLU DBG 0.0000007155 0.47432
404 2OBM ADP 0.002269 0.47395
405 3ZQ6 ADP ALF 0.000026 0.47385
406 1H65 GDP 0.000194 0.47371
407 4QOS ADP 0.0006721 0.47265
408 1YTM ATP 0.0002629 0.4724
409 2PL3 ADP 0.001438 0.47217
410 3ZFD ANP 0.0000006975 0.47091
411 3ZQ6 ADP ALF 0.00004429 0.47033
412 2CHG ANP 0.0003745 0.47009
413 2CHG ANP 0.0004792 0.46985
414 1VHT BA3 0.0008135 0.46869
415 1YTM ATP 0.0003289 0.46814
416 4D0N GDP 0.0000003462 0.4671
417 2DPY ADP 0.002399 0.46626
418 1H65 GDP 0.0003141 0.46471
419 1GXU 2HP 0.002075 0.46462
420 1VHT BA3 0.001001 0.46439
421 2CHG ANP 0.0005077 0.46417
422 1IN4 ADP 0.0005286 0.46339
423 2C9O ADP 0.0004363 0.46275
424 4OHY ANP 0.0002285 0.46236
425 1VHT BA3 0.001107 0.46229
426 3VM7 GLC 0.0023 0.46177
427 4ITR GDP 0.000006708 0.46067
428 3KTA AP5 0.001015 0.4594
429 2J0V GDP 0.000001954 0.4582
430 2C9O ADP 0.0005702 0.45765
431 3FVQ ATP 0.0005963 0.4568
432 1OW3 MGF 0.00000005802 0.45665
433 2J0V GDP 0.000002287 0.4561
434 2J0V GDP 0.000002558 0.45553
435 1Z6T ADP 0.0009894 0.45545
436 1Z6T ADP 0.0009982 0.45527
437 2J0V GDP 0.000003055 0.45408
438 1OYY AGS 0.002653 0.45344
439 1SVI GDP 0.0000009497 0.45344
440 1Z6T ADP 0.001102 0.45331
441 1D2N ANP 0.0007669 0.452
442 3B7G ANP 0.002381 0.45096
443 3B7G ANP 0.002505 0.44988
444 4OI4 ATP 0.0005809 0.44932
445 2CHG ANP 0.0007222 0.44915
446 2GK6 ADP 0.005977 0.44687
447 4OI4 ATP 0.0006997 0.44592
448 2ZTS ADP 0.001424 0.44411
449 2IXE ATP 0.0009603 0.44383
450 1W5T ADP 0.001825 0.44328
451 1Z6T ADP 0.001524 0.44279
452 2CK3 ANP 0.00154 0.44259
453 4A4Z ANP 0.004395 0.44245
454 1W5T ANP 0.00143 0.44012
455 1W5T ANP 0.001441 0.43998
456 1B0U ATP 0.002646 0.43995
457 3KTA AP5 0.001656 0.43732
458 3RLF ANP 0.001188 0.43621
459 1BO4 COA 0.006344 0.43445
460 1E4V AP5 0.001454 0.43398
461 1ZUI SKM 0.0008623 0.43391
462 1E4V AP5 0.001615 0.43312
463 2GK6 ADP 0.0102 0.43311
464 4DEC 3PG 0.01298 0.4326
465 2Q2Y ADP 0.005428 0.43103
466 2Q2Y MKR 0.005428 0.43103
467 3LN9 FLC 0.006432 0.43057
468 1L2T ATP 0.001381 0.43001
469 1L2T ATP 0.001381 0.43001
470 3BFX A3P 0.00308 0.42909
471 1XPJ TLA 0.03072 0.42833
472 3FWY ADP 0.00004996 0.42821
473 4E03 ADP 0.00001017 0.4274
474 4E03 ADP 0.00001017 0.4274
475 2OFW ADX 0.001613 0.42673
476 3IO3 ADP 0.00001771 0.42575
477 1QHH ATP 0.007905 0.42543
478 3IO3 ADP 0.00007054 0.42513
479 1K6M AGS 0.002735 0.42426
480 4GOX A3P 0.002316 0.42397
481 2CK3 ADP 0.002356 0.42366
482 3CV2 OXL 0.01748 0.42274
483 1A5Z FBP 0.01626 0.42262
484 1M7G ADX 0.001248 0.42215
485 4JLN 18V 0.0259 0.42171
486 4JLN UDP 0.0259 0.42171
487 3CV2 OXL 0.01821 0.42155
488 1YOE RIB 0.01404 0.42129
489 1YOE RIB 0.01404 0.42129
490 1YOE RIB 0.01404 0.42129
491 1YOE RIB 0.01404 0.42129
492 1M7G ADX 0.001328 0.4211
493 1M7G ADX 0.001328 0.4211
494 1M7G ADX 0.001328 0.4211
495 1M7G ADX 0.001328 0.4211
496 3BP1 GUN 0.02584 0.4205
497 3W6G FLC 0.01782 0.42042
498 1K6M AGS 0.002823 0.42033
499 2QEN ADP 0.00006236 0.42002
500 2VOH CIT 0.01164 0.41978
501 1X6V ADP 0.001306 0.41843
502 2GWH A3P 0.006437 0.41821
503 2OZE AGS 0.000147 0.41786
504 3QOX SAH 0.0006059 0.41728
505 2PEZ GGZ 0.001836 0.41701
506 2PEZ DAT 0.001836 0.41701
507 2Z5F A3P 0.004982 0.41631
508 1QAN SAH 0.003529 0.41624
509 2BVE PH5 0.01269 0.41622
510 4E03 ADP 0.000008824 0.41553
511 2J5V PCA 0.02378 0.41506
512 3W6G FLC 0.02241 0.41498
513 1G8S MET 0.02436 0.41477
514 2F5X ASP 0.02469 0.41325
515 3FB4 AP5 0.003773 0.41299
516 3ZIA ADP 0.00007191 0.41279
517 3ZIA ADP 0.00007294 0.41241
518 1M7G ADP 0.001927 0.41192
519 1M7G ADP 0.001972 0.41153
520 1M7G AV2 0.000008428 0.41111
521 1M7G AV2 0.000009023 0.40983
522 1M7G AV2 0.000009023 0.40983
523 1M7G AV2 0.00002974 0.40983
524 1M7G AV2 0.000009023 0.40983
525 3ITJ CIT 0.02228 0.40972
526 2V26 ADP 0.0004232 0.40972
527 1N13 AG2 0.02899 0.40964
528 3BP1 GUN 0.037 0.40957
529 3BP1 GUN 0.037 0.40957
530 1NJF AGS 0.0004789 0.40939
531 4PU6 ASP 0.02873 0.40922
532 2Q37 3AL 0.02976 0.40897
533 2QQC AG2 0.03115 0.40878
534 4MKG AP5 0.004812 0.40874
535 2BIF SIN 0.005726 0.4087
536 2BIF ANP 0.003229 0.4087
537 1S3G AP5 0.004981 0.40813
538 2ZL4 ALA ALA ALA ALA 0.0329 0.40796
539 1P4V GLY 0.03123 0.40795
540 3KJI ADP 0.0001865 0.40793
541 2ZJ5 ADP 0.03433 0.40781
542 2ZJ5 ADP 0.03433 0.40781
543 4P32 ADP 0.006648 0.40763
544 1HTW ADP 0.00005502 0.40745
545 4O48 ASP 0.03358 0.40741
546 2X7I CIT 0.02198 0.40728
547 1W0J ADP 0.0000976 0.40722
548 1NJF AGS 0.0004081 0.40721
549 4P32 ADP 0.006839 0.4071
550 4B2D FBP 0.01329 0.40709
551 4MKF AP5 0.005619 0.40705
552 2CE7 ADP 0.0000637 0.40704
553 4GBM A3P 0.005918 0.40675
554 4MUB A3P 0.009881 0.40636
555 4MUB A3P 0.009881 0.40636
556 1UJ2 C5P 0.001597 0.40627
557 1OS1 PYR 0.002943 0.40625
558 1GPM AMP 0.04004 0.40551
559 1U2Z SAH 0.00122 0.40549
560 1YXM ADE 0.03064 0.40539
561 2Q2Y MKR 0.005608 0.405
562 2Q2Y ADP 0.005956 0.405
563 4IP7 FBP 0.01478 0.40492
564 3KJI ADP 0.0002706 0.40485
565 1OS1 ATP 0.002991 0.40455
566 2CE7 ADP 0.00008613 0.40432
567 1HTW ADP 0.00004838 0.40427
568 1NN5 2DT 0.003594 0.40426
569 1NN5 ANP 0.003594 0.40426
570 1T3D CYS 0.04399 0.40425
571 1U2Z SAH 0.001363 0.40424
572 1IK4 PGH 0.02137 0.40419
573 3FYH ADP 0.005799 0.40417
574 3MB5 SAM 0.005807 0.40415
575 1NJF AGS 0.0006618 0.40407
576 2QG6 NMN 0.003655 0.40386
577 4MKF AP5 0.005991 0.40385
578 1LVG ADP 0.00000526 0.40367
579 2F5X ASP 0.03673 0.40351
580 3DCJ THH 0.01591 0.40342
581 1XKV ATP 0.0001324 0.40333
582 2F5X ASP 0.03744 0.40307
583 3ZGE ASP 0.03264 0.40305
584 4IOK ADP 0.002705 0.40298
585 1SQL GUN 0.04248 0.40251
586 1U2Z SAH 0.001223 0.4023
587 1WZU MLT 0.0391 0.40206
588 3ZGE ASP 0.0334 0.402
589 3ZGE ASP 0.0334 0.402
590 3BER AMP 0.02807 0.4019
591 3F9W SAH 0.03379 0.40151
592 2BVE PH5 0.03829 0.40113
593 3ZIA ATP 0.00005701 0.40096
594 3ZIA ATP 0.00005743 0.4009
595 2O66 FLC 0.04286 0.40086
596 2O66 FLC 0.04286 0.40086
597 2QJY UQ2 0.04226 0.40025
598 3M58 SAH 0.03048 0.40008
599 5NUL FMN 0.01597 0.40007
600 1LOB MMA 0.0465 0.40006
601 2QQC AG2 0.04271 0.4
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