Receptor
PDB id Resolution Class Description Source Keywords
1BIF 2 Å EC: 3.1.3.46 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE BIFUNCT ENZYME COMPLEXED WITH ATP-G-S AND PHOSPHATE RATTUS NORVEGICUS KINASE TRANSFERASE (PHOSPHO) PHOSPHATASE HYDROLASE (PHOSPGLYCOLYSIS BIFUNCTIONAL ENZYME
Ref.: THE CRYSTAL STRUCTURE OF THE BIFUNCTIONAL ENZYME 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATAS DISTINCT DOMAIN HOMOLOGIES. STRUCTURE V. 4 1017 1996
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
AGS A:500;
Valid;
none;
submit data
523.247 C10 H16 N5 O12 P3 S c1nc(...
GOL A:530;
Invalid;
none;
submit data
92.094 C3 H8 O3 C(C(C...
MG A:501;
Part of Protein;
none;
submit data
24.305 Mg [Mg+2...
PO4 A:510;
A:520;
Invalid;
Invalid;
none;
none;
submit data
94.971 O4 P [O-]P...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2BIF 2.4 Å EC: 3.1.3.46 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE H256A MUTANT WITH F6P IN PHOSPHATASE ACTIVE SITE RATTUS NORVEGICUS KINASE TRANSFERASE (PHOSPHO) PHOSPHATASE HYDROLASE (PHOSPHO) GLYCOLYSIS BIFUNCTIONAL ENZYME TRANSFERASE HYDROLASE
Ref.: CRYSTAL STRUCTURE OF THE H256A MUTANT OF RAT TESTIS FRUCTOSE-6-PHOSPHATE,2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE. FRUCTOSE 6-PHOSPHATE IN THE ACTIVE SITE LEADS TO MECHANISMS FOR BOTH MUTANT AND WILD TYPE BISPHOSPHATASE ACTIVITIES. J.BIOL.CHEM.
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 1BIF - AGS C10 H16 N5 O12 P3 S c1nc(c2c(n....
2 3BIF - SIN C4 H6 O4 C(CC(=O)O)....
3 2BIF - BOG C14 H28 O6 CCCCCCCCOC....
70% Homology Family (10)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 1BIF - AGS C10 H16 N5 O12 P3 S c1nc(c2c(n....
2 3BIF - SIN C4 H6 O4 C(CC(=O)O)....
3 2BIF - BOG C14 H28 O6 CCCCCCCCOC....
4 1K6M - AGS C10 H16 N5 O12 P3 S c1nc(c2c(n....
5 2DWO Ki = 8.3 uM PEP C3 H5 O6 P C=C(C(=O)O....
6 2AXN - F6P C6 H13 O9 P C(C1C(C(C(....
7 3QPV - F6P C6 H13 O9 P C(C1C(C(C(....
8 2I1V - F6P C6 H13 O9 P C(C1C(C(C(....
9 4MA4 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
10 3QPW - PEP C3 H5 O6 P C=C(C(=O)O....
50% Homology Family (10)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 1BIF - AGS C10 H16 N5 O12 P3 S c1nc(c2c(n....
2 3BIF - SIN C4 H6 O4 C(CC(=O)O)....
3 2BIF - BOG C14 H28 O6 CCCCCCCCOC....
4 1K6M - AGS C10 H16 N5 O12 P3 S c1nc(c2c(n....
5 2DWO Ki = 8.3 uM PEP C3 H5 O6 P C=C(C(=O)O....
6 2AXN - F6P C6 H13 O9 P C(C1C(C(C(....
7 3QPV - F6P C6 H13 O9 P C(C1C(C(C(....
8 2I1V - F6P C6 H13 O9 P C(C1C(C(C(....
9 4MA4 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
10 3QPW - PEP C3 H5 O6 P C=C(C(=O)O....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: AGS; Similar ligands found: 356
No: Ligand ECFP6 Tc MDL keys Tc
1 AGS 1 1
2 SAP 1 1
3 BA3 0.887324 0.92
4 AP5 0.875 0.92
5 B4P 0.875 0.92
6 A2D 0.859155 0.92
7 ATP 0.84 0.945946
8 5FA 0.828947 0.945946
9 AQP 0.828947 0.945946
10 ADP 0.8 0.945946
11 AR6 0.782051 0.92
12 APR 0.782051 0.92
13 M33 0.779221 0.907895
14 AD9 0.772152 0.921053
15 ACP 0.769231 0.921053
16 SRA 0.756757 0.972973
17 A22 0.75 0.933333
18 50T 0.746835 0.907895
19 AMP 0.743243 0.918919
20 A 0.743243 0.918919
21 ADX 0.734177 0.9
22 CA0 0.734177 0.896104
23 ADQ 0.732558 0.896104
24 ANP 0.731707 0.921053
25 ACQ 0.731707 0.921053
26 25L 0.730337 0.933333
27 PRX 0.716049 0.848101
28 OAD 0.715909 0.896104
29 ABM 0.714286 0.87013
30 ATF 0.714286 0.909091
31 AMP MG 0.701299 0.846154
32 A12 0.696203 0.909091
33 AP2 0.696203 0.909091
34 A1R 0.693182 0.8625
35 TAT 0.690476 0.986486
36 5AL 0.682353 0.883117
37 25A 0.681818 0.92
38 3OD 0.681319 0.896104
39 APC 0.674699 0.909091
40 ADP MG 0.670732 0.858974
41 AU1 0.670732 0.921053
42 SRP 0.666667 0.860759
43 ADP BEF 0.662651 0.8375
44 BEF ADP 0.662651 0.8375
45 G3A 0.65625 0.875
46 4AD 0.655556 0.873418
47 AFH 0.649485 0.841463
48 G5P 0.649485 0.875
49 00A 0.648352 0.839506
50 ADV 0.647059 0.884615
51 ADP PO3 0.647059 0.893333
52 RBY 0.647059 0.884615
53 BIS 0.645161 0.886076
54 GTA 0.642857 0.843373
55 ATP MG 0.639535 0.858974
56 AMO 0.637363 0.884615
57 PAJ 0.637363 0.841463
58 ITT 0.630952 0.893333
59 DLL 0.630435 0.883117
60 AHX 0.630435 0.851852
61 ADP VO4 0.629214 0.883117
62 NB8 0.62766 0.851852
63 UP5 0.623762 0.873418
64 SON 0.619048 0.884615
65 ALF ADP 0.617977 0.82716
66 ADP ALF 0.617977 0.82716
67 LAD 0.617021 0.819277
68 PR8 0.617021 0.809524
69 MAP 0.615385 0.897436
70 GAP 0.613636 0.848101
71 ANP MG 0.611111 0.85
72 FYA 0.610526 0.858974
73 ME8 0.610526 0.821429
74 TXA 0.610526 0.884615
75 PTJ 0.610526 0.851852
76 1ZZ 0.610526 0.8
77 PAP 0.609195 0.932432
78 ATR 0.609195 0.918919
79 NAI 0.607843 0.8625
80 NAX 0.607843 0.831325
81 ADP BMA 0.606383 0.871795
82 A4P 0.605769 0.804598
83 A2R 0.604396 0.933333
84 XYA 0.60274 0.8
85 RAB 0.60274 0.8
86 ADN 0.60274 0.8
87 T5A 0.59434 0.802326
88 139 0.59434 0.831325
89 TXD 0.592233 0.8625
90 DND 0.592233 0.884615
91 NXX 0.592233 0.884615
92 YAP 0.591837 0.85
93 FA5 0.591837 0.860759
94 XAH 0.585859 0.8
95 AP0 0.580952 0.851852
96 DAL AMP 0.580645 0.858974
97 2A5 0.579545 0.871795
98 AOC 0.578313 0.779221
99 COD 0.577982 0.795455
100 A3P 0.576471 0.918919
101 ATP A A A 0.575758 0.881579
102 CNA 0.574074 0.884615
103 LAQ 0.572816 0.865854
104 5AS 0.569767 0.804598
105 YLP 0.567308 0.781609
106 4TC 0.566038 0.851852
107 YLB 0.566038 0.781609
108 UPA 0.566038 0.8625
109 5N5 0.565789 0.776316
110 ADJ 0.564815 0.811765
111 3AM 0.560976 0.88
112 5CD 0.558442 0.763158
113 A4D 0.558442 0.8
114 A2P 0.55814 0.905405
115 NA7 0.556701 0.909091
116 PPS 0.554348 0.9
117 G5A 0.549451 0.804598
118 GSP 0.547368 0.924051
119 3AT 0.543478 0.92
120 TYM 0.542056 0.860759
121 MYR AMP 0.54 0.77907
122 AR6 AR6 0.538462 0.87013
123 EP4 0.5375 0.716049
124 YLC 0.537037 0.8
125 NAD 0.535714 0.883117
126 DTA 0.530864 0.792208
127 M2T 0.530864 0.719512
128 2AM 0.53012 0.893333
129 3DH 0.53012 0.75641
130 AHZ 0.528302 0.821429
131 IOT 0.527273 0.793103
132 DTP 0.526882 0.858974
133 A3D 0.526316 0.871795
134 SSA 0.526316 0.825581
135 MTA 0.52439 0.75641
136 YLA 0.522523 0.781609
137 BTX 0.522124 0.845238
138 6AD 0.521277 0.911392
139 AMP DBH 0.519231 0.848101
140 TAD 0.518868 0.8875
141 AYB 0.517857 0.772727
142 BT5 0.517544 0.835294
143 A5A 0.515789 0.833333
144 TSB 0.515464 0.845238
145 OVE 0.511628 0.933333
146 V3L 0.510638 0.92
147 AVV 0.510204 0.851852
148 7MD 0.509434 0.821429
149 LPA AMP 0.509259 0.843373
150 0WD 0.508772 0.875
151 NAE 0.508475 0.85
152 VMS 0.505155 0.813953
153 52H 0.505155 0.804598
154 54H 0.505155 0.813953
155 NSS 0.50505 0.825581
156 NAQ 0.504202 0.829268
157 EAD 0.504132 0.831325
158 FB0 0.504 0.769231
159 ZID 0.5 0.871795
160 5CA 0.5 0.825581
161 A3N 0.5 0.746835
162 ARU 0.5 0.819277
163 M24 0.5 0.809524
164 LA8 ALF 3PG 0.5 0.797619
165 IMO 0.5 0.88
166 RGT 0.5 0.909091
167 ZAS 0.5 0.728395
168 AV2 0.5 0.87013
169 53H 0.5 0.804598
170 ALF ADP 3PG 0.5 0.797619
171 AF3 ADP 3PG 0.5 0.797619
172 NJP 0.5 0.897436
173 NPW 0.495575 0.843373
174 NDP 0.495575 0.875
175 DDS 0.494737 0.833333
176 S4M 0.494382 0.655556
177 6FA 0.492188 0.802326
178 DZD 0.491379 0.841463
179 NZQ 0.491228 0.864198
180 P5A 0.490196 0.769231
181 DSZ 0.49 0.825581
182 LSS 0.49 0.786517
183 MAO 0.488889 0.724138
184 DSH 0.488636 0.710843
185 P1H 0.488 0.811765
186 N0B 0.487603 0.781609
187 YLY 0.487395 0.772727
188 ODP 0.486957 0.864198
189 NVA LMS 0.485149 0.786517
190 SFD 0.484615 0.776596
191 FAS 0.484615 0.811765
192 FAD 0.484615 0.811765
193 FDA 0.484375 0.795455
194 DAT 0.483871 0.858974
195 NAJ PZO 0.483051 0.807229
196 G A A A 0.482759 0.829268
197 7MC 0.482143 0.802326
198 LEU LMS 0.480392 0.786517
199 PO4 PO4 A A A A PO4 0.480392 0.855263
200 TXP 0.478261 0.875
201 NDE 0.47619 0.884615
202 KAA 0.475728 0.777778
203 GSU 0.475728 0.804598
204 5AD 0.474359 0.706667
205 NAD IBO 0.474138 0.82716
206 A3G 0.47191 0.759494
207 4TA 0.470085 0.770115
208 6C6 0.46875 0.8375
209 GP3 0.46875 0.875
210 NDC 0.46875 0.829268
211 SFG 0.468085 0.7125
212 YSA 0.46729 0.804598
213 FAY 0.466667 0.821429
214 DCA 0.466667 0.786517
215 ETB 0.466667 0.795455
216 A A A 0.466019 0.858974
217 128 0.464286 0.741573
218 RFL 0.463235 0.784091
219 PUA 0.46281 0.841463
220 A7D 0.462366 0.759494
221 FNK 0.459259 0.769231
222 COA 0.459016 0.806818
223 SA8 0.458333 0.674419
224 A5D 0.458333 0.792208
225 MHZ 0.457447 0.666667
226 NEC 0.455556 0.708861
227 GGZ 0.455446 0.851852
228 NAJ PYZ 0.455285 0.809524
229 SAI 0.453608 0.698795
230 SAH 0.453608 0.728395
231 GEK 0.45098 0.722892
232 SMM 0.45 0.674157
233 GTP 0.45 0.873418
234 6IA 0.44898 0.797619
235 SAM 0.44898 0.678161
236 TAP 0.448 0.935065
237 30N 0.448 0.776596
238 AMX 0.448 0.795455
239 CAO 0.448 0.8
240 COS 0.448 0.808989
241 CMX 0.444444 0.786517
242 EEM 0.444444 0.659091
243 SCO 0.444444 0.786517
244 AAT 0.444444 0.714286
245 P5F 0.443662 0.786517
246 PGS 0.442105 0.910256
247 FAM 0.440945 0.769231
248 ACO 0.440945 0.8
249 FCX 0.440945 0.76087
250 AMP NAD 0.44 0.8375
251 2SA 0.44 0.884615
252 NAP 0.44 0.896104
253 APU 0.439655 0.85
254 A U 0.439655 0.82716
255 D5M 0.43956 0.833333
256 DA 0.43956 0.833333
257 HAX 0.4375 0.769231
258 Z5A 0.436508 0.744444
259 1DG 0.436508 0.875
260 DG1 0.436508 0.875
261 V1N 0.436364 0.87013
262 S7M 0.435644 0.678161
263 2MC 0.435115 0.774194
264 AAM 0.434783 0.918919
265 WSA 0.434783 0.813953
266 FYN 0.434109 0.806818
267 NMN AMP PO4 0.433333 0.82716
268 NA0 0.433071 0.884615
269 AMZ 0.431818 0.868421
270 C2R 0.431818 0.857143
271 A3S 0.431579 0.769231
272 COK 0.430769 0.808989
273 MCD 0.430769 0.769231
274 SOP 0.430769 0.788889
275 CA6 0.430769 0.752577
276 OXK 0.430769 0.808989
277 GNH 0.43 0.8625
278 101 0.428571 0.833333
279 N6P 0.428571 0.866667
280 F2N 0.427586 0.777778
281 CO6 0.427481 0.808989
282 1VU 0.427481 0.8
283 CMC 0.427481 0.788889
284 NMX 0.427481 0.729167
285 GKE 0.427273 0.841463
286 GDC 0.427273 0.841463
287 GDD 0.427273 0.841463
288 SCA 0.425373 0.808989
289 FA9 0.424658 0.823529
290 K15 0.424528 0.651685
291 A6D 0.424528 0.729412
292 CAJ 0.424242 0.769231
293 SCD 0.424242 0.786517
294 AIR 0.423529 0.853333
295 6K6 0.423077 0.881579
296 A3T 0.42268 0.779221
297 NIA 0.422222 0.783133
298 NHD 0.421488 0.858974
299 MLC 0.421053 0.808989
300 1HE 0.421053 0.791209
301 12D 0.421053 0.75
302 3HC 0.421053 0.818182
303 1CZ 0.42029 0.820225
304 GDP 0.42 0.873418
305 0UM 0.419048 0.666667
306 CAA 0.41791 0.818182
307 MCA 0.41791 0.8
308 YE1 0.41791 0.777778
309 GCP 0.417476 0.851852
310 G1R 0.417476 0.8625
311 2CP 0.414815 0.78022
312 MC4 0.414815 0.765957
313 PLP AAD 0.414634 0.728261
314 NOS 0.414634 0.75
315 NVA 2AD 0.414141 0.707317
316 CA8 0.411765 0.770833
317 COW 0.411765 0.8
318 HGG 0.411765 0.808989
319 3CP 0.411765 0.788889
320 COF 0.411765 0.771739
321 BYC 0.411765 0.808989
322 MGP 0.411765 0.841463
323 1GZ 0.411765 0.8
324 IRC 0.411765 0.818182
325 2KQ 0.411765 0.791209
326 U G A 0.411765 0.8
327 3AD 0.411765 0.763158
328 N01 0.41129 0.858974
329 PA7 0.410526 0.674699
330 FAQ 0.408759 0.808989
331 4CA 0.408759 0.78022
332 BCA 0.408759 0.8
333 7RP 0.408602 0.878378
334 2VA 0.408163 0.759494
335 CO7 0.407407 0.808989
336 26A 0.406977 0.725
337 QQX 0.406593 0.857143
338 HXC 0.405797 0.791209
339 GRA 0.405797 0.808989
340 FAI 0.404255 0.868421
341 7RA 0.404255 0.906667
342 GPG 0.40367 0.864198
343 TGC 0.402878 0.8
344 SP1 0.402174 0.894737
345 RP1 0.402174 0.894737
346 QQY 0.402174 0.844156
347 ACK 0.402174 0.815789
348 BCO 0.40146 0.827586
349 S0N 0.4 0.769231
350 CO8 0.4 0.791209
351 2NE 0.4 0.791209
352 CIC 0.4 0.788889
353 TM1 0.4 0.738636
354 GNP 0.4 0.851852
355 8BR 0.4 0.860759
356 SLU 0.4 0.816092
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2BIF; Ligand: F6P; Similar sites found: 14
This union binding pocket(no: 1) in the query (biounit: 2bif.bio1) has 16 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc)
1 4IJ6 SEP 0.00007347 0.52236
2 3FDZ DG2 0.0003276 0.47613
3 3FDZ DG2 0.0003276 0.47613
4 3FDZ DG2 0.0003276 0.47613
5 3GP3 SEP 0.0005021 0.46785
6 3GP3 SEP 0.0005143 0.46735
7 2HHJ 3PG 0.0003942 0.4482
8 2HHJ DG2 0.0005894 0.44108
9 3LL4 2FP 0.001425 0.44074
10 3GP3 SEP 0.003311 0.43617
11 3GP3 SEP 0.003724 0.43355
12 3OI7 OI7 0.001699 0.42204
13 3OI7 OI7 0.001742 0.42163
14 3FDZ 3PG 0.006373 0.40089
Pocket No.: 2; Query (leader) PDB : 2BIF; Ligand: SIN; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 2bif.bio1) has 8 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc)
Pocket No.: 3; Query (leader) PDB : 2BIF; Ligand: BOG; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 2bif.bio1) has 15 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc)
Pocket No.: 4; Query (leader) PDB : 2BIF; Ligand: BOG; Similar sites found: 61
This union binding pocket(no: 4) in the query (biounit: 2bif.bio1) has 23 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc)
1 4QGE 35O 0.0000008911 0.59715
2 3O01 DXC 0.0001938 0.56246
3 2VWA PTY 0.001439 0.47352
4 1M2Z BOG 0.0008867 0.4669
5 2WOR 2AN 0.00414 0.44976
6 3AQT RCO 0.004849 0.44739
7 1ZPD CIT 0.006912 0.44026
8 1UO5 PIH 0.008712 0.43863
9 2VWA PTY 0.007712 0.43589
10 1XMY ROL 0.005523 0.43273
11 3RMK BML 0.007645 0.43214
12 1XN0 ROL 0.00571 0.43201
13 1XN0 ROL 0.006148 0.4304
14 2VWA PTY 0.009773 0.43026
15 1XMY ROL 0.006937 0.42777
16 1JGS SAL 0.02766 0.42754
17 2V5E SCR 0.01068 0.42675
18 2ALG DAO 0.01016 0.42593
19 2ALG DAO 0.01016 0.42593
20 2Q8H TF4 0.01261 0.42588
21 3N7S 3N7 0.01721 0.42529
22 1GEG GLC 0.01576 0.42327
23 3R9V DXC 0.013 0.42274
24 3R9V DXC 0.02219 0.42271
25 3G58 988 0.008395 0.41915
26 3G58 988 0.008432 0.41906
27 3G58 988 0.008553 0.41876
28 3HP9 CF1 0.02022 0.41835
29 3RV5 DXC 0.009064 0.4182
30 1N8V BDD 0.007343 0.41774
31 3WUR O4B 0.01352 0.41695
32 3KO0 TFP 0.02229 0.41657
33 3F8C HT1 0.01906 0.4161
34 2HHP FLC 0.02453 0.41608
35 2JC9 ADN 0.01752 0.41189
36 3ZQE DXC 0.02209 0.41136
37 4F4S EFO 0.01856 0.4106
38 1XM4 PIL 0.01036 0.4106
39 1XM4 PIL 0.01039 0.41054
40 3CAK DPF 0.01846 0.40998
41 4F4S EFO 0.01963 0.40934
42 1LTZ HBI 0.01983 0.40911
43 4N70 2HX 0.01146 0.40851
44 4EXS X8Z 0.009697 0.40809
45 3PEV IHP 0.03774 0.40766
46 3KP6 SAL 0.03212 0.4076
47 1X8D RNS 0.02389 0.40726
48 3JQA DX4 0.02308 0.40708
49 4DR9 BB2 0.01106 0.40542
50 3FEA ACE PHE MET AIB PM3 6CW GLU 1AC LEU NH2 0.01646 0.40482
51 3KO0 TFP 0.03387 0.4046
52 3F7Z 34O 0.01445 0.40369
53 4KWG 2AK 0.02515 0.40342
54 4IA6 EIC 0.02501 0.40168
55 4JCA CIT 0.04184 0.40166
56 4JCA CIT 0.04184 0.40166
57 1SBR VIB 0.02771 0.40157
58 1XMU ROF 0.01385 0.40087
59 1XMU ROF 0.01395 0.40071
60 4MGA 27L 0.03683 0.40059
61 2JE7 XMM 0.02959 0.40009
Pocket No.: 5; Query (leader) PDB : 2BIF; Ligand: F6P; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 5) in the query (biounit: 2bif.bio1) has 15 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc)
Pocket No.: 6; Query (leader) PDB : 2BIF; Ligand: BOG; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 6) in the query (biounit: 2bif.bio1) has 21 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc)
Pocket No.: 7; Query (leader) PDB : 2BIF; Ligand: SIN; Similar sites found: 648
This union binding pocket(no: 7) in the query (biounit: 2bif.bio1) has 42 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc)
1 2AWN ADP 0.00000458 0.66259
2 2AWN ADP 0.000004282 0.66032
3 1T5C ADP 0.00000325 0.65742
4 3A4M ADP 0.000001617 0.65575
5 1T5C ADP 0.000003541 0.65527
6 2VVG ADP 0.000006265 0.6421
7 2W58 ADP 0.000006437 0.64041
8 1GOJ ADP 0.000006633 0.63989
9 2VVG ADP 0.000007374 0.6368
10 2KIN ADP 0.000008875 0.63472
11 3LRE ADP 0.00001088 0.62969
12 3W5J GDP 0.000007973 0.62574
13 1JJ7 ADP 0.00001394 0.62395
14 3LRE ADP 0.00001471 0.6213
15 3LRE ADP 0.00001471 0.6213
16 2XT3 ADP 0.00001223 0.62065
17 1G6H ADP 0.00001707 0.61956
18 2PZE ATP 0.00001858 0.61401
19 3COB ADP 0.000017 0.61251
20 4AG5 ADP 0.00001582 0.60927
21 4FRZ ADP 0.00001691 0.6068
22 4KFU ACP 0.00001899 0.60395
23 1M7G AV2 0.00001092 0.60171
24 4AG5 ADP 0.00002403 0.59869
25 2CBZ ATP 0.000042 0.59219
26 3DC4 ADP 0.00002931 0.58687
27 2PZE ATP 0.00004948 0.5849
28 4QM7 GTP 0.00001639 0.58445
29 2OG2 MLI 0.00002542 0.57714
30 1YQT ADP 0.0000598 0.57657
31 2NCD ADP 0.00006133 0.5753
32 3TK1 GDP 0.00004867 0.57481
33 1LVG ADP 0.00005837 0.57049
34 3COB ADP 0.0000635 0.56848
35 3NHB ADP 0.00008546 0.56772
36 4BQS ADP 0.00007708 0.56388
37 4CVN ADP 0.00008233 0.56231
38 4CVN ADP 0.00009109 0.5599
39 4CVN ADP 0.00009561 0.55875
40 3UIE ANP 0.00005233 0.55815
41 3MD0 GDP 0.00007259 0.55778
42 2WHX ADP 0.0001484 0.55298
43 1JJV ATP 0.0001432 0.5523
44 4BQS ADP 0.00006856 0.55203
45 1OXV ANP 0.0001081 0.54854
46 2ZR9 DTP 0.00008477 0.54723
47 4NON GDP 0.00008835 0.54629
48 1XP8 AGS 0.0001203 0.54606
49 1M7G AV2 0.0001247 0.54523
50 1M7G AV2 0.0001247 0.54523
51 1M7G AV2 0.0001247 0.54523
52 1JI0 ATP 0.0001775 0.54404
53 3PQC GDP 0.0001785 0.54391
54 4KFU ACP 0.0001334 0.54367
55 1RE0 GDP 0.0001344 0.54349
56 1Y63 ADP 0.0001011 0.54324
57 3B9Q MLI 0.0001445 0.54298
58 2WJG GDP 0.0001396 0.54261
59 1OXV ANP 0.0001401 0.54252
60 1OXV ANP 0.0001408 0.54242
61 3CNL GNP 0.0001444 0.54183
62 4CVN ADP 0.0001487 0.54114
63 4LC1 GDP 0.0001174 0.53985
64 2WJG GDP 0.0001176 0.53981
65 4IHQ ADP 0.0001604 0.53938
66 2IYL GDP 0.0001211 0.53914
67 2IS6 ADP 0.0001214 0.53909
68 1I4D GDP 0.0001767 0.53714
69 4B47 GDP 0.0001782 0.53695
70 1MKY GDP 0.0001387 0.53608
71 1FZQ GDP 0.0001401 0.53585
72 1SVI GDP 0.0001885 0.53564
73 3UIE ANP 0.00008071 0.5356
74 2QN6 GDP 0.0001892 0.53555
75 3U6B GDP 0.0001941 0.53496
76 3N5C GDP 0.0001508 0.53417
77 3AQ4 GDP 0.0001161 0.53372
78 4J0Q GDP 0.000207 0.53347
79 3AQ4 GDP 0.0001187 0.53324
80 4J0Q GDP 0.0002367 0.53036
81 2HT6 GDP 0.0002379 0.53025
82 2HT6 GDP 0.0002391 0.53012
83 4J0Q GDP 0.0002394 0.5301
84 3N5C GDP 0.0001372 0.53003
85 1XMV ADP 0.000138 0.5299
86 4J0Q GDP 0.000255 0.52863
87 3B5J 12D 0.0003421 0.52844
88 4J0Q GDP 0.0002622 0.52799
89 3Q72 GNP 0.000271 0.52722
90 2DPY ADP 0.0003606 0.52719
91 1DS6 GDP 0.0002068 0.52702
92 2GDJ ANP 0.0002075 0.52694
93 3U6B GDP 0.0002815 0.52634
94 2CJW GDP 0.0002147 0.52618
95 1S9D GDP 0.0001726 0.52495
96 1XX6 ADP 0.0005165 0.52423
97 3IIJ ADP 0.0002483 0.52288
98 1SKQ GDP 0.0003338 0.52238
99 1YZG GDP 0.0001966 0.52207
100 4DKX GDP 0.0002822 0.51997
101 2ZFI ADP 0.0002838 0.51985
102 1Z0A GDP 0.0002918 0.51922
103 1XKV ATP 0.0001728 0.5191
104 3Q85 GNP 0.0002962 0.51888
105 2D2F ADP 0.0005957 0.51813
106 3ZIA ATP 0.0002375 0.51788
107 3ZIA ATP 0.0002378 0.51785
108 1RYH GNP 0.0001883 0.51724
109 2RCN GDP 0.0003209 0.51706
110 2RCN GDP 0.0003209 0.51706
111 1MR3 G3D 0.000247 0.51701
112 1Z0A GDP 0.000338 0.51589
113 4HSE ADP 0.0002598 0.51589
114 1V8K ANP 0.0003403 0.51573
115 1V8K ANP 0.0003403 0.51573
116 1ZJ6 G3D 0.0002633 0.5156
117 1ZJ6 G3D 0.0002633 0.5156
118 1ZJ6 G3D 0.0002633 0.5156
119 3GJ0 GDP 0.0003522 0.51496
120 2WMO GTP 0.00021 0.51487
121 3Q85 GNP 0.0003549 0.51478
122 3GJ4 GDP 0.0003554 0.51475
123 4A4Z ANP 0.0003597 0.51448
124 3WY9 GDP 0.0004699 0.51445
125 1Z6T ADP 0.0001312 0.5141
126 1D8T GDP 0.0003667 0.51404
127 3A1S GDP 0.0002853 0.51382
128 1Z6T ADP 0.0001351 0.5135
129 3GJ3 GDP 0.0003763 0.51346
130 3A1S GDP 0.0002924 0.51327
131 1U0J ADP 0.0005032 0.51286
132 2V7Q ATP 0.0002308 0.51284
133 1SQ5 ADP 0.0002994 0.51275
134 1YRB GDP 0.0001808 0.51264
135 1SQ5 ADP 0.0003012 0.51262
136 1D8T GDP 0.0003909 0.51259
137 1M7G AV2 0.0003021 0.51255
138 1Z6T ADP 0.0001435 0.51224
139 3GJ5 GDP 0.0003975 0.51221
140 1SQ5 ADP 0.0003086 0.51208
141 3WY9 GDP 0.0005292 0.51169
142 3BOS CDP 0.0004072 0.51167
143 3GJ7 GDP 0.0004078 0.51164
144 2X77 GDP 0.0003153 0.5116
145 1R6B ADP 0.0003179 0.51142
146 4G5G GDP 0.0004132 0.51134
147 3E70 GDP 0.0003206 0.51123
148 1KK1 GNP 0.0005527 0.51068
149 4DID GDP 0.000331 0.51052
150 3U6K GDP 0.0004286 0.51051
151 1F6B GDP 0.0003361 0.51018
152 4KFU ACP 0.001099 0.50987
153 2NGR GDP 0.0003515 0.50919
154 4DCT GDP 0.0003584 0.50876
155 3U6K GDP 0.0004729 0.50828
156 3WYA GDP 0.0004969 0.50716
157 3TH5 GNP 0.0002658 0.50447
158 3Q72 GNP 0.0004368 0.50438
159 3RC3 ANP 0.0007285 0.50427
160 1DAR GDP 0.0005752 0.50384
161 1G41 ADP 0.0003546 0.50353
162 4DKX GDP 0.0004543 0.50351
163 4TTQ ATP 0.0005987 0.50293
164 2WIC GNP 0.000478 0.50238
165 2WIC GNP 0.000478 0.50238
166 3CH5 GDP 0.0004941 0.50165
167 3CH5 GDP 0.0004941 0.50165
168 1Z6T ADP 0.0001944 0.50102
169 4KFU ACP 0.001603 0.49937
170 3GJ4 GDP 0.0005485 0.49934
171 2D7D ADP 0.0007033 0.49929
172 3GJ5 GDP 0.0005577 0.49897
173 3GJ8 GDP 0.0005645 0.4987
174 3GJ8 GDP 0.000569 0.49853
175 1A2K GDP 0.0005851 0.49791
176 1A2K GDP 0.0005851 0.49791
177 3GJ7 GDP 0.0005927 0.49762
178 1A4R GNH 0.0003304 0.49491
179 2QZ4 ADP 0.0005332 0.49469
180 1A2K GDP 0.001114 0.49441
181 1X6V ADP 0.00004646 0.49376
182 2VF7 ADP 0.0007113 0.49358
183 2A5J GDP 0.0005638 0.49348
184 1SKQ GDP 0.0007168 0.49341
185 4IEE AGS 0.001189 0.49291
186 1Z0F GDP 0.0007438 0.49259
187 1VHT BA3 0.0006258 0.49122
188 3LXR GDP 0.0006303 0.49106
189 1M7G ADX 0.00003586 0.49067
190 3ZIA ADP 0.0005327 0.48972
191 1GRN GDP 0.0004247 0.48969
192 3CPJ GDP 0.0005414 0.48937
193 3ZIA ADP 0.0005422 0.48934
194 2CHG ANP 0.0003448 0.48934
195 1GXU 2HP 0.0009302 0.48909
196 2QEN ADP 0.0004632 0.48789
197 1PUJ GNP 0.0005842 0.48776
198 1Z0A GDP 0.0007503 0.48729
199 1Z0A GDP 0.0007503 0.48729
200 1JWY ADP 0.0009706 0.48669
201 2VF7 ADP 0.0009719 0.48666
202 2VF7 ADP 0.0009719 0.48666
203 1KK8 BEF ADP 0.0004928 0.4866
204 1G7S GDP 0.0009825 0.48642
205 2VF7 ADP 0.0009905 0.48625
206 2VF7 ADP 0.0009905 0.48625
207 1A4R GDP 0.000465 0.48325
208 1D2E GDP 0.0007416 0.4827
209 4FCW ADP 0.001218 0.48166
210 1S8F GDP 0.0009856 0.48137
211 1S8F GDP 0.0009856 0.48137
212 4FCW ADP 0.001235 0.48136
213 1KY3 GDP 0.0007926 0.48129
214 1OFH ADP 0.0009926 0.48122
215 3TBK ANP 0.002523 0.48091
216 3PQC GDP 0.001037 0.48026
217 1Z0A GDP 0.001049 0.48003
218 1M7G ADP 0.0001041 0.47951
219 4E03 ADP 0.002154 0.47911
220 2GCO GNP 0.0007145 0.47888
221 1VHT BA3 0.001149 0.47804
222 2V7Q ADP 0.001804 0.47793
223 1G6O ADP 0.001183 0.47741
224 1G6O ADP 0.001183 0.47741
225 1M2Z BOG 0.005814 0.47721
226 1YTM ATP 0.0005068 0.47718
227 3TH5 GNP 0.0006262 0.47718
228 1D5C GDP 0.0007861 0.47689
229 2CHG ANP 0.0007927 0.47672
230 1OFH ADP 0.000992 0.47653
231 2JLR ANP 0.0009965 0.47643
232 1M7G ADP 0.0001248 0.47631
233 2PL3 ADP 0.002451 0.47611
234 4LPS GDP 0.001625 0.47527
235 2XAU ADP 0.001342 0.47469
236 1Z0A GDP 0.001082 0.47467
237 1Z0A GDP 0.001082 0.47467
238 2OBM ADP 0.004214 0.47449
239 1VHT BA3 0.001366 0.4743
240 2XAU ADP 0.001429 0.47333
241 1UPT GTP 0.0006205 0.47313
242 1YTM ATP 0.0006228 0.47306
243 3GJ0 GDP 0.00119 0.47266
244 1D2N ANP 0.000645 0.47236
245 4V0K GDP 0.0007965 0.47228
246 1IN4 ADP 0.0007964 0.47228
247 2CHG ANP 0.000806 0.47204
248 4U5X GNP 0.0008157 0.4718
249 2CK3 ANP 0.0008505 0.47095
250 2FAH GDP 0.001301 0.47077
251 1ZD9 GDP 0.0009011 0.46977
252 2BVN GNP 0.001366 0.46974
253 1B7T ADP 0.001703 0.46952
254 2W2X GSP 0.0006207 0.46908
255 1M7G ADX 0.0001301 0.46863
256 1M7G ADX 0.0001301 0.46863
257 1M7G ADX 0.0001301 0.46863
258 1M7G ADX 0.0001301 0.46863
259 1FNN ADP 0.0009569 0.46854
260 2BVN GNP 0.001459 0.46834
261 2EFE GNH 0.001482 0.46801
262 1FNN ADP 0.0009869 0.46791
263 4QOS ADP 0.001844 0.4678
264 2B8W ALF 5GP 0.0004497 0.46759
265 2FAH GDP 0.001549 0.46707
266 4E03 ADP 0.002369 0.46691
267 4E03 ADP 0.002369 0.46691
268 4KAX GTP 0.0007033 0.46663
269 2GCO GNP 0.001063 0.4664
270 3DEF GDP 0.001611 0.46624
271 2J59 GTP 0.000738 0.46569
272 1UPT GTP 0.0007491 0.46539
273 2FJU GSP 0.0009199 0.46526
274 2C9O ADP 0.0009463 0.4647
275 2G77 GDP 0.001431 0.46444
276 2BME GNP 0.000535 0.4643
277 2B8W ALF 5GP 0.0005531 0.46367
278 4ITR GDP 0.001228 0.46347
279 1XX6 ADP 0.003458 0.46317
280 3RWO GDP 0.001882 0.46293
281 2XN5 FUN 0.003503 0.46288
282 4LJ9 ACP 0.003548 0.46259
283 1M7B GTP 0.001053 0.46256
284 3VX3 ADP 0.001299 0.46232
285 2C04 GCP 0.001588 0.46228
286 2W2X GSP 0.001107 0.46156
287 4HI0 GDP 0.001112 0.46148
288 1O3Y GTP 0.000791 0.46054
289 1KAO GDP 0.001743 0.46034
290 2FAH GDP 0.001771 0.46001
291 4M9Q GNP 0.0009969 0.45979
292 1UKZ ADP 0.0001505 0.45971
293 4LPS GDP 0.002693 0.45958
294 1UJ2 ADP 0.000471 0.45953
295 3EZ2 ADP 0.005041 0.45936
296 3DKP ADP 0.004185 0.45884
297 2BCG GDP 0.001544 0.45879
298 2C9O ADP 0.00128 0.45866
299 2J59 GTP 0.0008928 0.45821
300 2J59 GTP 0.0008964 0.45813
301 4M9Q GNP 0.001087 0.4581
302 1FP6 ADP 0.002365 0.45808
303 2FNA ADP 0.0009183 0.45767
304 2QTV GNP 0.0007633 0.45758
305 3NKV GNP 0.001117 0.45755
306 2J59 GTP 0.0009308 0.4574
307 2J59 GTP 0.0009416 0.45718
308 1J2J GTP 0.0009477 0.45706
309 3REF GDP 0.001146 0.45706
310 2FAH GDP 0.002061 0.45685
311 2J59 GTP 0.0009692 0.45663
312 4M9Q GNP 0.001184 0.45642
313 2W83 GTP 0.0009878 0.45626
314 4FCW ADP 0.004726 0.45608
315 3KTA AP5 0.002598 0.45608
316 1XTQ GDP 0.001011 0.45582
317 2G77 AF3 0.008366 0.45582
318 1IHU AF3 0.001222 0.4558
319 2CHG ANP 0.001223 0.45578
320 2C04 GCP 0.001521 0.45522
321 1U8Z GDP 0.001264 0.45513
322 3REF GDP 0.001265 0.45512
323 2GK6 ADP 0.008354 0.45502
324 2FNA ADP 0.001283 0.45484
325 1W7J ADP BEF 0.002277 0.45478
326 1M2O GNP 0.0008872 0.45473
327 2VB6 ADP BEF 0.001316 0.45434
328 3PCR GTP 0.001117 0.45389
329 1G4U GDP 0.002039 0.45312
330 1NY5 ADP 0.002483 0.45297
331 2A5F GTP 0.0009775 0.4529
332 3B7G ANP 0.004496 0.45271
333 2BME GNP 0.0008832 0.45137
334 3HU3 AGS 0.001858 0.45121
335 1Z0K GTP 0.001287 0.45117
336 1R4A GNP 0.001074 0.45113
337 3IO3 ADP 0.004026 0.45085
338 3B7G ANP 0.004923 0.45069
339 1G16 GDP 0.001589 0.45064
340 1WDT GTP 0.002329 0.45041
341 3FKQ ATP 0.002814 0.45037
342 1Z0K GTP 0.001351 0.45023
343 1HE1 GDP 0.001958 0.45016
344 1HE1 AF3 0.01046 0.45003
345 1JWY GDP 0.003462 0.44999
346 2HF9 GSP 0.00288 0.44989
347 1U8Z GDP 0.001376 0.44988
348 2FH5 GTP 0.00199 0.44984
349 2FH5 GTP 0.00199 0.44984
350 2FH5 GTP 0.00199 0.44984
351 2EFE GNH 0.002423 0.4496
352 4H1V GNP 0.002944 0.44943
353 3H86 AP5 0.0004015 0.44936
354 1B0U ATP 0.003569 0.44934
355 2F9L GDP 0.001456 0.44879
356 2BME GNP 0.001022 0.44865
357 1HE1 GDP 0.002114 0.44863
358 2GCN GDP 0.001787 0.44834
359 1UJ2 C5P 0.0008701 0.44832
360 1WQ1 AF3 0.01159 0.44823
361 1O3Y GTP 0.001254 0.44819
362 4P4T GDP 0.002625 0.44797
363 2WKQ GTP 0.00154 0.44771
364 2C77 GNP 0.002218 0.44767
365 3DOE GTP 0.001557 0.4475
366 3TMK T5A 0.0004643 0.44688
367 1IHU ADP 0.001609 0.44687
368 3NKV GNP 0.001125 0.44686
369 1NRJ GTP 0.002343 0.44658
370 2OFW ADX 0.0001404 0.44625
371 1Z83 AP5 0.0003407 0.44616
372 1Z83 AP5 0.0003407 0.44616
373 2CK3 ADP 0.001703 0.44577
374 3BD9 A3P 0.006226 0.44548
375 1G3Q ADP 0.006244 0.44541
376 2OM2 GDP 0.002486 0.44538
377 1E96 GTP 0.001221 0.44534
378 1GRN AF3 0.01133 0.44509
379 3Q9L ATP 0.006424 0.44478
380 3Q9L ATP 0.006447 0.4447
381 3TMK T5A 0.0007494 0.44465
382 1CXZ GSP 0.00216 0.44462
383 1Z83 AP5 0.000379 0.4444
384 3TMK T5A 0.0005462 0.4441
385 3KUD GDP 0.002663 0.44401
386 2ZTS ADP 0.003192 0.44398
387 3FWY ADP 0.003832 0.44395
388 1TQ4 GDP 0.002703 0.44371
389 1TU3 GNP 0.00136 0.44334
390 2B8T THM 0.002335 0.44309
391 1OYY AGS 0.008381 0.44306
392 1NH8 AMP 0.01217 0.44292
393 3T12 GDP ALF 0.002372 0.44278
394 3MJH GTP 0.001413 0.44264
395 2JAQ DCP 0.002101 0.44173
396 4LHW GNP 0.001547 0.44095
397 1EK0 GNP 0.001566 0.44072
398 2OM2 GDP 0.002698 0.44025
399 2GK6 ADP 0.01388 0.44023
400 4LHW GNP 0.001614 0.44016
401 4LHW GNP 0.001928 0.44005
402 2OZE AGS 0.003892 0.43993
403 1W4R TTP 0.001214 0.43912
404 1BO4 COA 0.009982 0.43908
405 2BME GNP 0.002045 0.43894
406 4LX0 BEF GDP 0.001732 0.43885
407 3H86 AP5 0.0004554 0.43856
408 1Z06 GNP 0.002106 0.43838
409 4KVG GTP 0.00179 0.43824
410 1M2O GNP 0.001793 0.4382
411 1M2O GNP 0.001793 0.4382
412 4LHW GNP 0.001813 0.438
413 3FIU POP 0.0162 0.43794
414 1KMQ GNP 0.002601 0.43761
415 1FP6 ADP 0.004376 0.43754
416 2NGR AF3 0.01616 0.43659
417 1NF3 GNP 0.002324 0.43652
418 3TKL GTP 0.002329 0.43647
419 3QBT GNP 0.00204 0.43581
420 2C78 GNP 0.003463 0.43535
421 4NU0 AP5 0.0003384 0.43528
422 1UAD GNP 0.002491 0.4352
423 4KBF AMP 0.0145 0.43474
424 4KBF AMP 0.0145 0.43474
425 3QBT GNP 0.002178 0.43459
426 4V0K GDP 0.002582 0.43452
427 1W4R TTP 0.001337 0.43443
428 1TU3 GNP 0.001891 0.43413
429 3QBT GNP 0.002243 0.43404
430 1X1R GDP 0.001906 0.43399
431 1Z2A GDP 0.003166 0.43382
432 4MUB A3P 0.005281 0.4337
433 4MUB A3P 0.005281 0.4337
434 4DSU GDP 0.001949 0.43358
435 1S3G AP5 0.0002733 0.43346
436 2Y8E GNP 0.002328 0.43335
437 3FYH ADP 0.002754 0.4333
438 4IDN GNP 0.00199 0.4332
439 1ION ADP 0.009113 0.4331
440 3FIU POP 0.01944 0.43299
441 1IBR GNP 0.002014 0.43299
442 1G7C 5GP 0.01306 0.43297
443 1QF9 ALF 0.0004702 0.4327
444 1QF9 C5P 0.0004702 0.4327
445 1QF9 ADP 0.0004702 0.4327
446 3BC1 GNP 0.002426 0.43259
447 1YZK GNP 0.002874 0.43249
448 1IBR GNP 0.002078 0.43241
449 1WQ1 GDP 0.003422 0.43232
450 1YZN GNP 0.00209 0.4323
451 4KVG GTP 0.002472 0.43224
452 3BC1 GNP 0.002479 0.43218
453 3MJH GTP 0.002108 0.43215
454 3QBT GNP 0.002501 0.43202
455 1ZIN AP5 0.0003057 0.43176
456 1GOT GDP 0.004161 0.43175
457 2Y8E GNP 0.00263 0.43108
458 2Y8E GNP 0.00263 0.43108
459 4K81 GTP 0.002236 0.43107
460 2D7C GTP 0.002637 0.43103
461 4TMZ GSP 0.003685 0.43089
462 4TMZ GSP 0.003688 0.43088
463 1NST A3P 0.007179 0.43086
464 1F5N GNP 0.002286 0.43067
465 2V26 ADP 0.004396 0.43066
466 1OS1 ATP 0.001654 0.43066
467 3TMK T5A 0.0007488 0.43044
468 2IXE ATP 0.004494 0.43023
469 4NCN GTP 0.003859 0.43
470 1GUA GNP 0.002372 0.42999
471 4NCN GTP 0.003903 0.42978
472 3WYG GTP 0.002043 0.42977
473 3WYF GTP 0.002058 0.42964
474 1H65 GDP 0.004652 0.42955
475 1NF3 GNP 0.002861 0.42952
476 2XTN GTP 0.004028 0.42917
477 1LFD GNP 0.002921 0.42913
478 1GP2 GDP 0.004074 0.42896
479 1AKY AP5 0.0005159 0.42869
480 1UAD GNP 0.003005 0.4286
481 1TX4 ALF GDP 0.004163 0.42854
482 1YVD GNP 0.00303 0.42845
483 2C5L GTP 0.002597 0.42834
484 2C5L GTP 0.002617 0.42819
485 3WYF GTP 0.002256 0.42799
486 3DDC GNP 0.002654 0.42794
487 3DDC GNP 0.002654 0.42794
488 3DZD ADP 0.009926 0.42758
489 1YZQ GNP 0.002722 0.42747
490 4MKG AP5 0.0004102 0.4273
491 1FQJ GDP 0.005219 0.42729
492 1NVU GTP 0.00278 0.42709
493 1NVU GTP 0.00278 0.42709
494 2QG6 NMN 0.002376 0.42706
495 1LFD GNP 0.003273 0.42701
496 1Y3A GDP 0.004527 0.42693
497 1OS1 PYR 0.001745 0.42693
498 3FVQ ATP 0.006266 0.42688
499 1P72 ADP 0.001282 0.4268
500 1P72 ADP 0.001282 0.4268
501 4K81 GTP 0.002846 0.42666
502 1Z08 GNP 0.004609 0.42658
503 4HDO GNP 0.002905 0.42628
504 1NVV GNP 0.002917 0.42621
505 1NVV GNP 0.002917 0.42621
506 1NVV GNP 0.002917 0.42621
507 1NVV GNP 0.002917 0.42621
508 4NU0 AP5 0.000443 0.42613
509 1W5T ANP 0.006588 0.42587
510 1H65 GDP 0.005618 0.42584
511 4LHW GNP 0.003505 0.42574
512 1VG8 GNP 0.00301 0.42564
513 1W5T ANP 0.006672 0.42562
514 1VG8 GNP 0.003012 0.42562
515 4P32 ADP 0.005716 0.4255
516 1TU3 GNP 0.002598 0.42546
517 3FB4 AP5 0.0004692 0.42526
518 4HAT GNP 0.002663 0.42501
519 1OIX GDP 0.00312 0.42498
520 1FQK GDP 0.005044 0.42484
521 4OHY ANP 0.004327 0.42474
522 4G8N G8M 0.01368 0.42425
523 3IUY AMP 0.0164 0.42391
524 1VG8 GNP 0.003359 0.42363
525 2QQ0 THM 0.002117 0.42357
526 1VG8 GNP 0.003386 0.42348
527 1W5T ADP 0.01035 0.42323
528 2D7C GTP 0.003436 0.42321
529 4K81 GTP 0.002997 0.42288
530 3RWO GDP 0.0041 0.42282
531 3RWO GDP 0.0041 0.42282
532 1FQJ ALF 0.0317 0.42256
533 4GOX A3P 0.005687 0.42252
534 4P32 ADP 0.00666 0.4225
535 1FQJ GDP 0.005767 0.42225
536 2X7I CIT 0.02097 0.42214
537 1M48 FRG 0.02986 0.42182
538 3RLF ANP 0.005902 0.42181
539 4K81 GTP 0.003193 0.42174
540 1FQK GDP 0.005967 0.42159
541 1ZUI SKM 0.001122 0.42134
542 2I4I AMP 0.02581 0.42123
543 1Z0J GTP 0.003853 0.42112
544 3KTA AP5 0.00845 0.42088
545 2GJ8 ALF GDP 0.003922 0.42079
546 3IUY AMP 0.02253 0.4205
547 1R2Q GNP 0.001391 0.42033
548 1FQK ALF 0.03452 0.42018
549 1Z08 GNP 0.006426 0.42016
550 1Z08 GNP 0.006426 0.42016
551 3IO3 ADP 0.01026 0.42013
552 1WF3 GNP 0.004078 0.42008
553 4NON GDP 0.003545 0.41987
554 4HDQ GNP 0.00414 0.4198
555 2ORV 4TA 0.004977 0.41921
556 2ORV 4TA 0.004977 0.41921
557 3TNF GNP 0.003685 0.41917
558 4NE2 ADP 0.001502 0.41907
559 3NOJ PYR 0.04664 0.41903
560 3NOJ PYR 0.04664 0.41903
561 1ZC3 GNP 0.005043 0.41897
562 1NH8 AMP 0.03657 0.41836
563 3Q9L ATP 0.01308 0.41833
564 1L2T ATP 0.006224 0.41786
565 1L2T ATP 0.006224 0.41786
566 2XTZ GSP 0.005369 0.4178
567 2CL6 CAG 0.005586 0.41706
568 3BFX A3P 0.01193 0.41704
569 1KHT AMP 0.03106 0.41687
570 1KHT AMP 0.03106 0.41687
571 4MKF AP5 0.0003714 0.41659
572 2GJ8 ALF GDP 0.004959 0.4165
573 1OE0 TTP 0.005003 0.41634
574 1FQJ ALF 0.04003 0.41634
575 1NN5 ANP 0.002802 0.41612
576 1NN5 2DT 0.002802 0.41612
577 3BER AMP 0.02734 0.41606
578 1N4K I3P 0.03671 0.41582
579 2Z5F A3P 0.01103 0.41553
580 2GWH A3P 0.01512 0.4153
581 3LN9 FLC 0.02546 0.41528
582 2QQ0 ANP 0.002626 0.41473
583 2XTZ GSP 0.006343 0.41469
584 2QQ0 TMP 0.002678 0.41439
585 2QQ0 ADP 0.002678 0.41439
586 4QC6 30N 0.008802 0.41408
587 1ZCB GDP 0.006573 0.41403
588 1S7N COA 0.01209 0.41368
589 1AZT GSP 0.004351 0.41356
590 1CS4 GSP 0.005103 0.41331
591 1ZC3 GNP 0.00609 0.41274
592 3ZQ6 ADP ALF 0.006275 0.41219
593 2RGX AP5 0.0008318 0.41214
594 4NE2 ADP 0.002021 0.41187
595 3E5H GNP 0.007387 0.41185
596 3E5H GNP 0.007387 0.41185
597 1OE0 TTP 0.007643 0.41122
598 1S8F GDP 0.00577 0.4111
599 1S8F GDP 0.00577 0.4111
600 1S8F GDP 0.00577 0.4111
601 3ZS9 ADP ALF 0.009228 0.41038
602 4MKF AP5 0.0004031 0.4103
603 3MGB PAP 0.01451 0.41002
604 1Z08 GNP 0.008156 0.41001
605 2PEZ GGZ 0.0001111 0.40983
606 2PEZ DAT 0.0001111 0.40983
607 1XEX ATP 0.008333 0.4096
608 4QC6 30N 0.01126 0.40932
609 1QHG ATP 0.02332 0.40931
610 1WA5 GTP 0.004199 0.40919
611 1BH2 GSP 0.005726 0.4087
612 1AQU A3P 0.02092 0.40849
613 2HF9 GSP 0.009016 0.40814
614 2WOJ ADP ALF 0.007871 0.40804
615 2WOJ ADP ALF 0.007982 0.40778
616 1T8U A3P 0.01648 0.40746
617 1T8U A3P 0.01648 0.40746
618 1UKZ AMP 0.01657 0.40735
619 2BEK ATP 0.01459 0.40705
620 1TAD ALF 0.006388 0.40676
621 1TAD GDP 0.006388 0.40676
622 2XTZ GSP 0.008475 0.40668
623 1E2K TMC 0.001607 0.40657
624 1Z08 GNP 0.00853 0.40656
625 4OI4 ATP 0.01322 0.40621
626 1QHH ATP 0.03672 0.40584
627 4OI4 ATP 0.01348 0.40583
628 4NE2 SH2 0.002568 0.40579
629 1MZV AMP 0.04292 0.40566
630 3CX8 GSP 0.006888 0.40543
631 1S7N COA 0.01593 0.40531
632 4BQS K2Q 0.003115 0.4049
633 4BQS ADP 0.003115 0.4049
634 4NE2 SH2 0.002722 0.40486
635 4F2O QUS 0.03344 0.40466
636 4F2O QUS 0.03344 0.40466
637 3ZQ6 ADP ALF 0.008253 0.40465
638 3TDC 0EU 0.03962 0.4046
639 3QXM NDZ 0.0388 0.40459
640 1SVK ALF GDP 0.006508 0.40402
641 3ZS9 ADP ALF 0.009832 0.40396
642 4GW8 3RA 0.04687 0.40362
643 2ODE ALF GDP 0.005819 0.4036
644 1CM0 COA 0.03598 0.40305
645 4NSQ COA 0.02713 0.40303
646 2WD7 VGD 0.03872 0.40146
647 3BFV ADP 0.03367 0.40141
648 4GBM A3P 0.01733 0.40097
Pocket No.: 8; Query (leader) PDB : 2BIF; Ligand: ANP; Similar sites found: 644
This union binding pocket(no: 8) in the query (biounit: 2bif.bio1) has 33 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc)
1 2AWN ADP 0.000002664 0.66259
2 2AWN ADP 0.000002487 0.66032
3 1T5C ADP 0.000001843 0.65742
4 3A4M ADP 0.0000008568 0.65575
5 1T5C ADP 0.000002012 0.65527
6 2VVG ADP 0.000003608 0.6421
7 2W58 ADP 0.00000371 0.64041
8 1GOJ ADP 0.000003826 0.63989
9 2VVG ADP 0.000004264 0.6368
10 2KIN ADP 0.000005154 0.63472
11 3LRE ADP 0.000006352 0.62969
12 3W5J GDP 0.000004544 0.62574
13 1JJ7 ADP 0.000008186 0.62395
14 3LRE ADP 0.000008649 0.6213
15 3LRE ADP 0.000008649 0.6213
16 2XT3 ADP 0.000007042 0.62065
17 1G6H ADP 0.000009643 0.62044
18 2PZE ATP 0.00001098 0.61401
19 3COB ADP 0.000009871 0.61251
20 4AG5 ADP 0.000009026 0.60927
21 4FRZ ADP 0.000009668 0.6068
22 4KFU ACP 0.00001089 0.60395
23 1M7G AV2 0.000005991 0.60171
24 4AG5 ADP 0.00001386 0.59869
25 2CBZ ATP 0.00002531 0.59219
26 3DC4 ADP 0.00001674 0.58687
27 2PZE ATP 0.0000295 0.5849
28 4QM7 GTP 0.000008957 0.58445
29 2OG2 MLI 0.00001591 0.57714
30 1YQT ADP 0.00003629 0.57594
31 2NCD ADP 0.00003623 0.5753
32 3TK1 GDP 0.00002817 0.57481
33 1LVG ADP 0.00003395 0.57049
34 3COB ADP 0.00003702 0.56848
35 3NHB ADP 0.00005115 0.56761
36 4BQS ADP 0.00004516 0.56388
37 4CVN ADP 0.00004832 0.56231
38 4CVN ADP 0.0000536 0.5599
39 4CVN ADP 0.00005633 0.55875
40 3UIE ANP 0.00002952 0.55815
41 3MD0 GDP 0.00004188 0.55778
42 2WHX ADP 0.00008967 0.55298
43 1JJV ATP 0.00008642 0.5523
44 4BQS ADP 0.00003897 0.55203
45 1OXV ANP 0.00006305 0.54854
46 2ZR9 DTP 0.00004846 0.54723
47 4NON GDP 0.00005056 0.54629
48 1XP8 AGS 0.00007036 0.54606
49 1M7G AV2 0.00007298 0.54523
50 1M7G AV2 0.00007298 0.54523
51 1M7G AV2 0.00007298 0.54523
52 1JI0 ATP 0.0001063 0.54404
53 3PQC GDP 0.0001069 0.54391
54 4KFU ACP 0.0000782 0.54367
55 1RE0 GDP 0.00007882 0.54349
56 1Y63 ADP 0.00005807 0.54324
57 3B9Q MLI 0.00009242 0.54298
58 2WJG GDP 0.00008197 0.54261
59 1OXV ANP 0.00008227 0.54252
60 1OXV ANP 0.00008267 0.54242
61 3CNL GNP 0.00008485 0.54183
62 4CVN ADP 0.00008745 0.54114
63 4LC1 GDP 0.0000677 0.53985
64 2WJG GDP 0.00006783 0.53981
65 4IHQ ADP 0.00009456 0.53938
66 2IYL GDP 0.00006993 0.53914
67 2IS6 ADP 0.00007007 0.53909
68 1I4D GDP 0.0001044 0.53714
69 4B47 GDP 0.0001053 0.53695
70 1MKY GDP 0.00008034 0.53608
71 1FZQ GDP 0.00008118 0.53585
72 1SVI GDP 0.0001116 0.53564
73 3UIE ANP 0.00004488 0.5356
74 2QN6 GDP 0.000112 0.53555
75 3U6B GDP 0.000115 0.53496
76 3N5C GDP 0.00008759 0.53417
77 3AQ4 GDP 0.00006609 0.53372
78 4J0Q GDP 0.0001228 0.53347
79 3AQ4 GDP 0.00006759 0.53324
80 4J0Q GDP 0.0001409 0.53036
81 2HT6 GDP 0.0001417 0.53025
82 2HT6 GDP 0.0001424 0.53012
83 4J0Q GDP 0.0001426 0.5301
84 3N5C GDP 0.00007845 0.53003
85 1XMV ADP 0.00007891 0.5299
86 4J0Q GDP 0.0001521 0.52863
87 3B5J 12D 0.0002083 0.52844
88 4J0Q GDP 0.0001566 0.52799
89 3Q72 GNP 0.000162 0.52722
90 2DPY ADP 0.0002199 0.52719
91 1DS6 GDP 0.0001211 0.52702
92 2GDJ ANP 0.0001216 0.52694
93 3U6B GDP 0.0001684 0.52634
94 2CJW GDP 0.0001259 0.52618
95 1S9D GDP 0.0000993 0.52495
96 1XX6 ADP 0.000322 0.52423
97 3IIJ ADP 0.0001483 0.52256
98 1SKQ GDP 0.0002021 0.52222
99 1YZG GDP 0.0001135 0.52207
100 4DKX GDP 0.0001667 0.51997
101 2ZFI ADP 0.0001677 0.51985
102 1Z0A GDP 0.0001725 0.51922
103 1XKV ATP 0.00009822 0.5191
104 3Q85 GNP 0.0001752 0.51888
105 2D2F ADP 0.0003879 0.51813
106 2RCN GDP 0.000182 0.51804
107 2RCN GDP 0.000182 0.51804
108 3ZIA ATP 0.0001379 0.51788
109 3ZIA ATP 0.0001381 0.51785
110 1RYH GNP 0.0001073 0.51724
111 1MR3 G3D 0.0001436 0.51701
112 4HSE ADP 0.0001512 0.51589
113 1Z0A GDP 0.0002007 0.51589
114 1V8K ANP 0.0002021 0.51573
115 1V8K ANP 0.0002021 0.51573
116 1ZJ6 G3D 0.0001533 0.5156
117 1ZJ6 G3D 0.0001533 0.5156
118 1ZJ6 G3D 0.0001533 0.5156
119 3GJ0 GDP 0.0002094 0.51496
120 2WMO GTP 0.00012 0.51487
121 3Q85 GNP 0.000211 0.51478
122 3GJ4 GDP 0.0002113 0.51475
123 4A4Z ANP 0.0002139 0.51448
124 3WY9 GDP 0.000285 0.51445
125 1Z6T ADP 0.00007216 0.5141
126 1D8T GDP 0.0002182 0.51404
127 3A1S GDP 0.0001665 0.51382
128 1Z6T ADP 0.00007434 0.5135
129 3GJ3 GDP 0.000224 0.51346
130 3A1S GDP 0.0001708 0.51327
131 1U0J ADP 0.0003058 0.51286
132 2V7Q ATP 0.0001322 0.51284
133 1SQ5 ADP 0.000175 0.51275
134 1YRB GDP 0.0001016 0.51264
135 1SQ5 ADP 0.0001761 0.51262
136 1D8T GDP 0.000233 0.51259
137 1M7G AV2 0.0001766 0.51255
138 1Z6T ADP 0.00007914 0.51224
139 3GJ5 GDP 0.0002371 0.51221
140 1SQ5 ADP 0.0001805 0.51208
141 3WY9 GDP 0.000322 0.51169
142 3BOS CDP 0.000243 0.51167
143 3GJ7 GDP 0.0002433 0.51164
144 2X77 GDP 0.0001846 0.5116
145 1R6B ADP 0.0001861 0.51142
146 4G5G GDP 0.0002466 0.51134
147 3E70 GDP 0.0001877 0.51123
148 1KK1 GNP 0.0003367 0.51068
149 4DID GDP 0.000194 0.51052
150 3U6K GDP 0.0002561 0.51051
151 1F6B GDP 0.0001971 0.51018
152 4KFU ACP 0.0007164 0.50987
153 2NGR GDP 0.0002064 0.50919
154 4DCT GDP 0.0002105 0.50876
155 3U6K GDP 0.0002834 0.50828
156 3WYA GDP 0.0002981 0.50716
157 3TH5 GNP 0.0001511 0.50447
158 3Q72 GNP 0.000258 0.50438
159 3RC3 ANP 0.0004471 0.50427
160 1DAR GDP 0.0003465 0.50384
161 1G41 ADP 0.0002057 0.50353
162 4DKX GDP 0.0002686 0.50351
163 4TTQ ATP 0.0003611 0.50293
164 2WIC GNP 0.0002831 0.50238
165 2WIC GNP 0.0002831 0.50238
166 3CH5 GDP 0.0002929 0.50165
167 3CH5 GDP 0.0002929 0.50165
168 1Z6T ADP 0.0001068 0.50102
169 4KFU ACP 0.001054 0.49937
170 3GJ4 GDP 0.0003261 0.49934
171 2D7D ADP 0.000426 0.49929
172 3GJ5 GDP 0.0003317 0.49897
173 3GJ8 GDP 0.0003358 0.4987
174 3GJ8 GDP 0.0003386 0.49853
175 1A2K GDP 0.0003485 0.49791
176 1A2K GDP 0.0003485 0.49791
177 3GJ7 GDP 0.0003531 0.49762
178 1A4R GNH 0.0001868 0.49491
179 2QZ4 ADP 0.000313 0.49469
180 1A2K GDP 0.0006917 0.49441
181 2VF7 ADP 0.0004259 0.49358
182 2A5J GDP 0.0003315 0.49348
183 1SKQ GDP 0.0004293 0.49341
184 4IEE AGS 0.0007392 0.49291
185 1Z0F GDP 0.000446 0.49259
186 1VHT BA3 0.000369 0.49122
187 3LXR GDP 0.0003718 0.49106
188 3ZIA ADP 0.000309 0.48972
189 1GRN GDP 0.0002419 0.48969
190 3CPJ GDP 0.0003142 0.48937
191 3ZIA ADP 0.0003147 0.48934
192 2CHG ANP 0.0001929 0.48934
193 1GXU 2HP 0.0006295 0.48909
194 2QEN ADP 0.0002645 0.48789
195 1PUJ GNP 0.0003398 0.48776
196 1Z0A GDP 0.0004448 0.48729
197 1Z0A GDP 0.0004448 0.48729
198 1JWY ADP 0.0005863 0.48669
199 2VF7 ADP 0.0005871 0.48666
200 2VF7 ADP 0.0005871 0.48666
201 1KK8 BEF ADP 0.0002819 0.4866
202 1G7S GDP 0.0005937 0.48642
203 2VF7 ADP 0.0005987 0.48625
204 2VF7 ADP 0.0005987 0.48625
205 1A4R GDP 0.0002625 0.48325
206 1D2E GDP 0.0004344 0.4827
207 4FCW ADP 0.0007405 0.48166
208 1S8F GDP 0.0005889 0.48137
209 1S8F GDP 0.0005889 0.48137
210 4FCW ADP 0.000751 0.48136
211 1KY3 GDP 0.0004652 0.48129
212 1OFH ADP 0.0005931 0.48122
213 3TBK ANP 0.001619 0.48091
214 1X6V ADP 0.0000481 0.48047
215 3PQC GDP 0.0006207 0.48026
216 1Z0A GDP 0.0006276 0.48003
217 4E03 ADP 0.001361 0.47911
218 2GCO GNP 0.0004133 0.47888
219 1VHT BA3 0.0006897 0.47804
220 2V7Q ADP 0.001121 0.47793
221 1G6O ADP 0.0007108 0.47741
222 1G6O ADP 0.0007108 0.47741
223 1M2Z BOG 0.004097 0.47721
224 1YTM ATP 0.0002836 0.47718
225 3TH5 GNP 0.0003567 0.47718
226 1D5C GDP 0.000456 0.47689
227 2CHG ANP 0.00046 0.47672
228 2JLR ANP