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Receptor
PDB id Resolution Class Description Source Keywords
1CL0 2.5 Å EC: 1.6.4.5 CRYSTAL STRUCTURE OF REDUCED THIOREDOXIN REDUCTASE FROM ESCH COLI. ESCHERICHIA COLI FLAVOENZYME OXIDOREDUCTASE
Ref.: CRYSTAL STRUCTURE OF REDUCED THIOREDOXIN REDUCTASE ESCHERICHIA COLI: STRUCTURAL FLEXIBILITY IN THE ISOALLOXAZINE RING OF THE FLAVIN ADENINE DINUCLEOTI COFACTOR. PROTEIN SCI. V. 8 2366 1999
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
FAD A:500;
Valid;
none;
submit data
785.55 C27 H33 N9 O15 P2 Cc1cc...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1TDF 2.3 Å EC: 1.6.4.5 CRYSTAL STRUCTURE OF ESCHERICHIA COLI THIOREDOXIN REDUCTASE 2 ANGSTROM RESOLUTION: IMPLICATIONS FOR A LARGE CONFORMATIOD URING CATALYSIS ESCHERICHIA COLI OXIDOREDUCTASE(FLAVOENZYME)
Ref.: CRYSTAL STRUCTURE OF ESCHERICHIA COLI THIOREDOXIN R REFINED AT 2 A RESOLUTION. IMPLICATIONS FOR A LARGE CONFORMATIONAL CHANGE DURING CATALYSIS. J.MOL.BIOL. V. 236 800 1994
Members (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 1TDF - NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
2 1CL0 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
3 1TRB - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
4 1TDE - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
70% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 1TDF - NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
2 1CL0 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
3 1TRB - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
4 1TDE - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
50% Homology Family (7)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 1FL2 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
2 3ITJ - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
3 1VDC - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
4 4YKF - NAI C21 H29 N7 O14 P2 c1nc(c2c(n....
5 1HYU - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
6 4YKG - NAD C21 H27 N7 O14 P2 c1cc(c[n+]....
7 1CL0 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: FAD; Similar ligands found: 128
No: Ligand ECFP6 Tc MDL keys Tc
1 FAD 1 1
2 FAS 1 1
3 FAY 0.859259 0.9875
4 RFL 0.852941 0.963855
5 6FA 0.794118 0.987654
6 FAE 0.751773 0.987654
7 SFD 0.651007 0.860215
8 FDA 0.641892 0.906977
9 FNK 0.602564 0.876405
10 62F 0.572327 0.939024
11 F2N 0.566265 0.886364
12 FMN 0.543307 0.876543
13 FA9 0.526316 0.939759
14 6YU 0.516304 0.860215
15 P6G FDA 0.511628 0.908046
16 FAD NBT 0.508876 0.83871
17 A2D 0.504065 0.875
18 P5F 0.491329 0.941176
19 FAD CNX 0.488506 0.8125
20 AR6 0.488372 0.851852
21 APR 0.488372 0.851852
22 AGS 0.484615 0.811765
23 SAP 0.484615 0.811765
24 M33 0.484375 0.864198
25 BA3 0.484127 0.875
26 HEJ 0.48062 0.851852
27 ATP 0.48062 0.851852
28 ADP 0.480315 0.851852
29 B4P 0.480315 0.875
30 AP5 0.480315 0.875
31 ANP 0.477273 0.831325
32 AQP 0.476923 0.851852
33 5FA 0.476923 0.851852
34 48N 0.469388 0.902439
35 OAD 0.467626 0.876543
36 9X8 0.467626 0.833333
37 FAD NBA 0.467033 0.793814
38 GTA 0.465753 0.892857
39 AN2 0.465116 0.841463
40 AT4 0.465116 0.821429
41 AD9 0.462121 0.831325
42 3OD 0.460993 0.876543
43 RBF 0.460938 0.790123
44 FB0 0.460606 0.835165
45 139 0.460526 0.858824
46 AP0 0.46 0.835294
47 A22 0.459854 0.864198
48 ACP 0.458015 0.853659
49 8QN 0.456522 0.864198
50 PRX 0.454545 0.831325
51 A3R 0.453237 0.86747
52 A1R 0.453237 0.86747
53 G3A 0.452055 0.902439
54 T5A 0.45098 0.872093
55 G5P 0.44898 0.902439
56 ATF 0.448529 0.821429
57 50T 0.44697 0.819277
58 6YZ 0.445255 0.853659
59 ACQ 0.444444 0.853659
60 CNV FAD 0.443182 0.917647
61 ADQ 0.442857 0.853659
62 PAJ 0.442857 0.847059
63 5AL 0.441176 0.864198
64 ADX 0.439394 0.775281
65 CA0 0.439394 0.853659
66 A4P 0.437909 0.831461
67 25L 0.4375 0.864198
68 P33 FDA 0.436464 0.817204
69 5SV 0.435714 0.793103
70 OMR 0.434211 0.818182
71 TXE 0.434211 0.890244
72 ABM 0.434109 0.829268
73 A 0.433071 0.82716
74 AMP 0.433071 0.82716
75 4AD 0.432624 0.855422
76 ADJ 0.432258 0.818182
77 B5M 0.431507 0.878049
78 B5Y 0.431507 0.878049
79 BIS 0.430556 0.802326
80 SRA 0.429688 0.788235
81 AFH 0.42953 0.825581
82 NXX 0.427632 0.865854
83 DND 0.427632 0.865854
84 UP5 0.427632 0.878049
85 6V0 0.427632 0.857143
86 TXD 0.427632 0.890244
87 DQV 0.426667 0.8875
88 SRP 0.42446 0.843373
89 PR8 0.423611 0.837209
90 T99 0.423358 0.821429
91 TAT 0.423358 0.821429
92 AMO 0.422535 0.865854
93 TXA 0.42069 0.865854
94 FYA 0.42069 0.864198
95 PTJ 0.42069 0.835294
96 CNA 0.420382 0.865854
97 00A 0.41958 0.823529
98 AHX 0.41958 0.835294
99 MAP 0.41844 0.811765
100 NAI 0.418301 0.845238
101 AU1 0.41791 0.831325
102 A12 0.416667 0.843373
103 AP2 0.416667 0.843373
104 25A 0.415493 0.851852
105 9ZA 0.415493 0.845238
106 9ZD 0.415493 0.845238
107 COD 0.415094 0.842697
108 4TC 0.412903 0.879518
109 APC 0.411765 0.843373
110 ME8 0.410959 0.806818
111 1ZZ 0.410959 0.806818
112 NB8 0.410959 0.835294
113 4UW 0.409091 0.825581
114 NAX 0.409091 0.837209
115 F2R 0.408805 0.850575
116 RBY 0.408759 0.843373
117 ADV 0.408759 0.843373
118 P1H 0.405882 0.818182
119 OOB 0.405594 0.864198
120 LAD 0.40411 0.825581
121 A A 0.40411 0.829268
122 UPA 0.403846 0.86747
123 4UU 0.401316 0.833333
124 GA7 0.401316 0.865854
125 A3D 0.401235 0.876543
126 80F 0.401235 0.808989
127 XAH 0.4 0.806818
128 DLL 0.4 0.864198
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1TDF; Ligand: NAP; Similar sites found with APoc: 783
This union binding pocket(no: 1) in the query (biounit: 1tdf.bio1) has 68 residues
No: Leader PDB Ligand Sequence Similarity
1 1QAN SAH None
2 4NTO 1PW 0.966184
3 5N6C NAD 1
4 2GQ2 NAP 1.16279
5 2AUY NAG MAN MMA 1.19048
6 2AR6 NAG MAN MAN MAN NAG 1.19048
7 1N2X SAM 1.3289
8 1X87 NAD 1.58228
9 1ZGS XMM 1.58228
10 1GZ4 ATP 1.58228
11 4R5M NAP 1.58228
12 4OH4 ANP 1.58228
13 3A27 SAM 1.58228
14 1O5I NAD 1.60643
15 5U5G NAP 1.69492
16 1RP0 AHZ 1.76056
17 2G5C NAD 1.77936
18 5BW4 SAM 1.87266
19 4Z0H NAD 1.89873
20 2Z3Y F2N 1.89873
21 4ZGS NAD 1.89873
22 4OPC PGT 1.89873
23 4OPC FDA 1.89873
24 1QMG APX 1.89873
25 2D3N GLC GLC GLC 1.89873
26 5A1T NAI 1.89873
27 5KVS NAP 1.89873
28 4IJP 1EH 1.89873
29 5A1T OXM 1.89873
30 4OM8 NAD 1.94175
31 1FK8 NAD 1.94553
32 3WMX NAD 1.95531
33 4E13 NAD 2.12014
34 5KVA SAM 2.15827
35 5BSH PRO 2.16606
36 3FUU ADN 2.21402
37 2IVD FAD 2.21519
38 4MO2 FDA 2.21519
39 4MO2 FAD 2.21519
40 6FHO FAD 2.21519
41 2HJR APR 2.21519
42 1F8G NAD 2.21519
43 5UR0 NAD 2.21519
44 1GAD NAD 2.21519
45 3HDY FAD 2.21519
46 3HDY FDA 2.21519
47 3HDY GDU 2.21519
48 1L7E NAI 2.21519
49 2YX1 SFG 2.21519
50 5Z75 NAD 2.21519
51 1YKF NAP 2.21519
52 4XQC NAD 2.21519
53 4XQC 13D 2.21519
54 3WGT QSC 2.21519
55 1WVG APR 2.21519
56 3WGT FAD 2.21519
57 3VGL ANP 2.21519
58 5YPU ATP 2.21519
59 1ZH8 NAP 2.21519
60 1RPN NDP 2.21519
61 1OBB NAD 2.21519
62 3I6I NDP 2.21519
63 2X2M X2M 2.2293
64 5XVH NAP 2.28758
65 5X9D 80F 2.30263
66 2A42 ATP 2.30769
67 2A40 ATP 2.30769
68 1YJQ NAP 2.31023
69 2AHR NAP 2.3166
70 1G6H ADP 2.33463
71 4KIL 1R5 2.34742
72 2EWM NAD 2.40964
73 3B1F NAD 2.41379
74 4YAG NAI 2.42215
75 1NM5 NAD 2.46305
76 3X0V FAD 2.53165
77 5OC1 FAD 2.53165
78 1H82 FAD 2.53165
79 2VYN NAD 2.53165
80 1H82 GZZ 2.53165
81 3B20 NAD 2.53165
82 3B1J NAD 2.53165
83 1LDM NAD 2.53165
84 9LDT NAD 2.53165
85 9LDB NAD 2.53165
86 1OMO NAD 2.53165
87 1GZ6 NAI 2.53165
88 1BXG NAD 2.53165
89 6EL3 NAP 2.53165
90 4CJN QNZ 2.53165
91 1YS4 NAP 2.53165
92 1I1E DM2 2.53165
93 1GQ2 NAP 2.53165
94 1X7D NAD 2.53165
95 3OA2 NAD 2.53165
96 4L8V NAP 2.53165
97 1F06 NDP 2.53165
98 1LJ8 NAD 2.53165
99 4E5N NAD 2.53165
100 1LLU NAD 2.53165
101 4BJZ P3A 2.53165
102 4BJZ FAD 2.53165
103 5T96 79J 2.53165
104 3MN6 ATP 2.53165
105 1ZBQ NAD 2.53165
106 3V1U NAD 2.53165
107 5YAP NAI 2.53165
108 1GPE FAD 2.53165
109 4J1Q NDP 2.53165
110 5BJX UDP 2.53165
111 5YAP 8S0 2.53165
112 4AT0 FAD 2.53165
113 5BJX NAD 2.53165
114 6A3J NAI 2.53165
115 1NVM NAD 2.5641
116 3WBF NAP 2.62295
117 3WBF API 2.62295
118 5ZI9 FLC 2.69231
119 5H20 GLC 2.7027
120 4EA7 JB2 2.72727
121 4EA7 COA 2.72727
122 3H8V ATP 2.73973
123 2VT3 ATP 2.7907
124 3IHG FAD 2.8481
125 4FWE FAD 2.8481
126 1MUU NAD 2.8481
127 1WDK NAD 2.8481
128 1MV8 NAD 2.8481
129 1J0X NAD 2.8481
130 5MBX FAD 2.8481
131 5MBX SP5 2.8481
132 5CAE COA 2.8481
133 1GY8 NAD 2.8481
134 1J49 NAD 2.8481
135 4C4A SAH 2.8481
136 1V8B NAD 2.8481
137 2GCG NDP 2.8481
138 5TC4 NAD 2.8481
139 1WPQ NAD 2.8481
140 1PZG A3D 2.8481
141 1Y1P NMN AMP PO4 2.8481
142 1HDR NAD 2.86885
143 2OOR NAD 2.87356
144 2BGM NAJ 2.8777
145 3A1I UNU 2.87908
146 2QQF A1R 2.92208
147 1P77 ATR 2.94118
148 6AA8 NAD 2.98013
149 5NM7 GLY 3.00752
150 5GT9 NAP 3.04183
151 5Y8L NAD 3.05085
152 5Y8L HUI 3.05085
153 3ZYR ASN NAG NAG BMA MAN MAN NAG NAG 3.06513
154 2PWY SAH 3.10078
155 2Q46 NAP 3.16206
156 5Y77 FAD 3.16456
157 5UAO FAD 3.16456
158 3AXB FAD 3.16456
159 3Q9T FAY 3.16456
160 1LTH NAD 3.16456
161 4D7E FAD 3.16456
162 6C4N NAP 3.16456
163 3NYC FAD 3.16456
164 3NYC IAR 3.16456
165 3V1Y NAD 3.16456
166 5LD5 NAD 3.16456
167 2V6G NAP 3.16456
168 6C4M NAP 3.16456
169 3NJ4 NAD 3.16456
170 3M89 GSP 3.16456
171 2PT9 S4M 3.16456
172 4IV9 FAD 3.16456
173 5EOW FAD 3.16456
174 4DPL NAP 3.16456
175 4PLT NAI 3.16456
176 6BQ6 TER 3.16456
177 4J36 FAD 3.16456
178 4PLT OXM 3.16456
179 3DAG FEG 3.16456
180 4J36 1HR 3.16456
181 5MLR NAP 3.16456
182 3AXB PRO 3.16456
183 5Y80 IRE 3.19489
184 1M0S CIT 3.19635
185 1I9G SAM 3.21429
186 3VPH NAD 3.22581
187 3VPH OXM 3.22581
188 3OFK SAH 3.24074
189 4CQM NAP 3.27869
190 5JE8 NAD 3.31126
191 3RFV 15L 3.37079
192 5NC1 NAG 3.37553
193 1C3X 8IG 3.38346
194 5OCM NAP 3.43643
195 5N2I NAP 3.44828
196 5ZYN FAD 3.48101
197 2XVF FAD 3.48101
198 4EIP K2C 3.48101
199 4EIP FAD 3.48101
200 2RGH FAD 3.48101
201 2XVE FAD 3.48101
202 1Y8Q ATP 3.48101
203 1X14 NAD 3.48101
204 3K5I AIR 3.48101
205 6C4T NA7 3.48101
206 1CF2 NAP 3.48101
207 1RM4 NDP 3.48101
208 4KVL PLM 3.48101
209 5SXS NIZ 3.48101
210 4U8P FDA 3.48101
211 4U8P UDP 3.48101
212 3HWW AKG 3.48101
213 4XDY NAI 3.48101
214 1YKJ FAD 3.48101
215 1YKJ PHB 3.48101
216 2PK3 A2R 3.48101
217 2YYY NAP 3.48101
218 2IXB NAD 3.48101
219 3ZL8 ADP 3.48101
220 4MOP 2H5 3.48101
221 4GKV NAD 3.48101
222 5G4L NDP 3.4965
223 1P1C SAH 3.51759
224 2YY7 NAD 3.52564
225 2I7C AAT 3.53357
226 1PVC ILE SER GLU VAL 3.65448
227 3F5A SIA GAL NAG 3.65854
228 1UJP CIT 3.69004
229 4XJ2 FMN 3.7234
230 4YCA NDP 3.7415
231 2QA1 FAD 3.79747
232 3E1T FAD 3.79747
233 5EVY FAD 3.79747
234 1E1M NAP 3.79747
235 1E1M FAD 3.79747
236 1Q9I FAD 3.79747
237 1Q9I TEO 3.79747
238 1DSS NAD 3.79747
239 2Q1W NAD 3.79747
240 3ABI NAD 3.79747
241 3CIF NAD 3.79747
242 2A92 NAI 3.79747
243 2FR1 NDP 3.79747
244 1D1T NAD 3.79747
245 3RYC GTP 3.79747
246 3ORF NAD 3.79747
247 5ERG SAM 3.79747
248 4JNE ATP 3.79747
249 3CIF G3H 3.79747
250 5YU3 NAD 3.79747
251 5YU3 PRO 3.79747
252 2EV9 SKM 3.80228
253 2EV9 NAP 3.80228
254 3BMN NAP 3.81944
255 3JQA NAP 3.81944
256 3BMO NAP 3.81944
257 5JDC NAP 3.81944
258 5JDI NAP 3.81944
259 3JQF NAP 3.81944
260 5JCJ NAP 3.81944
261 3BMQ NAP 3.81944
262 5K6A NAP 3.81944
263 3JQ7 NAP 3.81944
264 4CM4 NAP 3.81944
265 3JQG NAP 3.81944
266 2VOH CIT 3.82166
267 5ZZ6 ADP 3.84615
268 5ZZ6 NAD 3.84615
269 3EGI ADP 3.8835
270 6FS8 E4Z 3.90244
271 1DIG NAP 3.92157
272 3MB5 SAM 3.92157
273 2FF3 ATP 4
274 5A96 GTP 4.01606
275 5UAV NDP 4.03727
276 5UAV TFB 4.03727
277 6F9Q NAD 4.04412
278 5TTJ FAD 4.08163
279 1LC3 NAD 4.08163
280 2WD7 NAP 4.10448
281 3GMB FAD 4.11392
282 5KMS FAD 4.11392
283 3NKS FAD 4.11392
284 1PJS NAD 4.11392
285 4Z24 FAD 4.11392
286 2RGO FAD 4.11392
287 5KMS NAD 4.11392
288 4DSG UDP 4.11392
289 4DSG FAD 4.11392
290 3QV1 NAD 4.11392
291 4XFR CIT 4.11392
292 5YEC ATP 4.11392
293 2VHW NAI 4.11392
294 1EZ4 NAD 4.11392
295 2B4R AES 4.11392
296 4BVA NDP 4.11392
297 2B4R NAD 4.11392
298 1PFK ADP 4.11392
299 4GCZ FMN 4.11392
300 3SSO SAH 4.11392
301 5DF1 58X 4.11392
302 5DF1 NAP 4.11392
303 3T34 GDP 4.11392
304 1UAY ADN 4.13223
305 3GGO NAI 4.14013
306 5O22 C3R 4.15225
307 1NE7 AGP 4.15225
308 2CVZ NDP 4.15225
309 4D3F NAP 4.19355
310 3MAG SAH 4.23453
311 4EES FMN 4.34783
312 2PV7 NAD 4.36242
313 3W6X HZP 4.36681
314 3MCT SAH 4.3771
315 2R4J FAD 4.39122
316 2R4J 13P 4.39122
317 1LVW TYD 4.40678
318 2GMH FAD 4.43038
319 1KNR FAD 4.43038
320 5ZBC FAD 4.43038
321 5HXI FAD 4.43038
322 5HXI 5HN 4.43038
323 1KJ8 GAR 4.43038
324 3GFB NAD 4.43038
325 1BXK NAD 4.43038
326 4XDZ NDP 4.43038
327 6DNT NAD 4.43038
328 1EBF NAD 4.43038
329 5A1S FLC 4.43038
330 1D4D FAD 4.43038
331 5E4R NAP 4.43038
332 4HXY NDP 4.43038
333 4TM3 FAD 4.43038
334 5HV7 RBL 4.43038
335 1E3I CXF 4.43038
336 4YT4 FE9 4.43038
337 2B9W FAD 4.48113
338 2BDG PBZ 4.4843
339 1WP4 NDP 4.49827
340 1KOL NAD 4.52261
341 1H5Q NAP 4.5283
342 1NVT NAP 4.52962
343 1W8D NAP 4.63576
344 1W73 NAP 4.63576
345 1E6E FAD 4.6875
346 2HK9 ATR 4.72727
347 2HK9 NAP 4.72727
348 2RGJ FAD 4.74684
349 1GTE FAD 4.74684
350 5I39 FAD 4.74684
351 5FJN FAD 4.74684
352 5FJN BE2 4.74684
353 1COY FAD 4.74684
354 3T31 FAD 4.74684
355 3T31 DCQ 4.74684
356 2IZ1 ATR 4.74684
357 5Z20 NAI 4.74684
358 1COY AND 4.74684
359 2EFX NFA 4.74684
360 2I3G NAP 4.74684
361 4X9M FAD 4.74684
362 4PLG OXM 4.74684
363 4PLG NAI 4.74684
364 2C29 NAP 4.74684
365 5G3U ITW 4.74684
366 4YNU LGC 4.74684
367 5G3U FDA 4.74684
368 4YNU FAD 4.74684
369 4MDH NAD 4.74684
370 3OZ2 FAD 4.78589
371 4F8L AES 4.82759
372 4HSU FAD 4.83871
373 4GUT FAD 4.83871
374 4GUS FAD 4.83871
375 3WDX BGC BGC GLC 5.03356
376 5BUK FAD 5.06329
377 2YVF NAD 5.06329
378 2YVF FAD 5.06329
379 2DFV NAD 5.06329
380 5BVA FAD 5.06329
381 3K7M FAD 5.06329
382 5H81 NAP 5.06329
383 4RPL FAD 5.06329
384 4RPL 3UC 5.06329
385 3KB6 NAD 5.06329
386 6BWL NAD 5.06329
387 5MSO NAP 5.06329
388 4CBX ATP 5.06329
389 5X7Q GLC GLC 5.06329
390 4TQG NDP 5.06329
391 3E3U NVC 5.07614
392 3LCC SAH 5.10638
393 5O4J SAH 5.10949
394 5O4J PJL 5.10949
395 5O4J 9KH 5.10949
396 5X20 NAD 5.12821
397 1V1A KDG 5.17799
398 1I2L DCS 5.20446
399 3I7V B4P 5.22388
400 1L1E SAH 5.22648
401 1RYI FAD 5.2356
402 1RYI GOA 5.2356
403 5AOA PPI 5.24476
404 4Y9D NAI 5.2459
405 5J5Z FAD 5.37975
406 1PN0 IPH 5.37975
407 1PN0 FAD 5.37975
408 3GDN FAD 5.37975
409 5GZ6 NDP 5.37975
410 1BW9 NAD 5.37975
411 5GZ6 7C3 5.37975
412 1C1X NAD 5.37975
413 3GDN HBX 5.37975
414 4ZCC NAI 5.37975
415 4ZCC FAD 5.37975
416 4OOE NDP 5.37975
417 1E7S NAP 5.37975
418 1JQ3 AAT 5.40541
419 2Q97 ATP 5.42636
420 5KKA 6V0 5.44872
421 4O0L NDP 5.45455
422 5AYV NAP 5.50162
423 5AYV KPL 5.50162
424 3SJ7 NDP 5.55556
425 1ZQ9 SAM 5.61404
426 1I36 NAP 5.68182
427 2GVC FAD 5.6962
428 2WET FAD 5.6962
429 1VQW FAD 5.6962
430 2GV8 FAD 5.6962
431 6F7L FAD 5.6962
432 3OJO NAD 5.6962
433 6F97 FAD 5.6962
434 2GV8 NDP 5.6962
435 1PL6 NAD 5.6962
436 2J5V PCA 5.6962
437 1PL6 572 5.6962
438 5NUF NAD 5.6962
439 1C0I BE2 5.6962
440 1C0I FAD 5.6962
441 1H2B NAJ 5.6962
442 5NUE NAD 5.6962
443 5OJL TXP 5.7047
444 2GAG FAD 5.71429
445 2GAG FOA 5.71429
446 2GAG NAD 5.71429
447 1E3W NAD 5.74713
448 1E6W NAD 5.76923
449 1KYQ NAD 5.83942
450 2UVO NAG 5.84795
451 2UVO NDG 5.84795
452 3DXY SAM 5.9633
453 5MQ6 NDP 6.01266
454 5HSA FAS 6.01266
455 2AQJ TRP 6.01266
456 2AQJ FAD 6.01266
457 1CER NAD 6.01266
458 2E5V FAD 6.01266
459 2NU8 COA 6.01266
460 5A04 BGC 6.01266
461 5A04 NDP 6.01266
462 4YAC NAI 6.06061
463 3AB4 LYS 6.17978
464 4NAE 1GP 6.22222
465 1O6Z NAD 6.27063
466 1LUA NAP 6.27178
467 1W6U NAP 6.29139
468 1J5P NAD 6.32411
469 5BRT FAD 6.32911
470 2DKH FAD 6.32911
471 5BRT CH9 6.32911
472 2DKH 3HB 6.32911
473 5WGR FAD 6.32911
474 3GF4 FAD 6.32911
475 3GF4 UPG 6.32911
476 3X0D SAH 6.32911
477 6F3M NAD 6.32911
478 5TE1 7A2 6.32911
479 1HKU NAD 6.32911
480 2X6T NAP 6.32911
481 4MP8 MLI 6.32911
482 4MP8 NAD 6.32911
483 2RI1 GLP 6.38298
484 4YSX FAD 6.41026
485 1LSS NAD 6.42857
486 5CUO COA 6.43564
487 1EQ2 NAP 6.45161
488 5EES NAP 6.47773
489 1B55 4IP 6.50888
490 4GV8 DUP 6.50888
491 3OID TCL 6.58915
492 2Y6Q FAD 6.64557
493 5TUK FAD 6.64557
494 5X68 FAD 6.64557
495 2JB2 FAD 6.64557
496 2JB2 PHE 6.64557
497 2Y6Q I7T 6.64557
498 4RQU NAD 6.64557
499 1SOW NAD 6.64557
500 4CNK FAD 6.64557
501 4M37 SAH 6.64557
502 4M38 SAH 6.64557
503 1SAY PYR 6.6482
504 1JNR FAD 6.66667
505 2GJ3 FAD 6.66667
506 2XWL CTP 6.72646
507 4B4U NAP 6.93069
508 1JA9 NDP 6.93431
509 1C3V NDP 6.93878
510 1PS9 FAD 6.96203
511 1NAA 6FA 6.96203
512 2A8X FAD 6.96203
513 1PS9 NAP 6.96203
514 1NAA ABL 6.96203
515 4D04 NAP 6.96203
516 4D04 FAD 6.96203
517 1HDG NAD 6.96203
518 3L4S NAD 6.96203
519 3L4S 3PG 6.96203
520 1KEV NDP 6.96203
521 3C1O NAP 6.96203
522 1I8T FAD 6.96203
523 2FK8 SAM 6.96203
524 5K4W NAI 6.96203
525 4ZRN NAD 7.05128
526 1JAY NAP 7.07547
527 5E5U MLI 7.19697
528 3G89 SAM 7.22892
529 5YB7 FAD 7.27848
530 5YB7 ORN 7.27848
531 2Q1S NAI 7.27848
532 4W6Z 8ID 7.27848
533 5ZI2 ADP 7.27848
534 5ZI2 NAD 7.27848
535 1VI2 NAD 7.33333
536 3AD8 NAD 7.38916
537 4XZ3 ACP 7.3913
538 1VM6 NAD 7.45614
539 1FWV SGA MAG FUC 7.46269
540 2PKA BEN 7.5
541 5DJU FMN 7.58621
542 4M52 FAD 7.59494
543 2YG3 FAD 7.59494
544 1QO8 FAD 7.59494
545 3QJ4 FAD 7.59494
546 5TUF FAD 7.59494
547 4M52 M52 7.59494
548 4C3Y FAD 7.59494
549 1A5Z NAD 7.59494
550 4C3Y ANB 7.59494
551 3A06 NDP 7.59494
552 4CJX NAP 7.59494
553 3L9W AMP 7.59494
554 3L9W GSH 7.59494
555 4B63 NAP 7.59494
556 4B63 FAD 7.59494
557 4B63 ORN 7.59494
558 1SC6 NAD 7.59494
559 1CDO NAD 7.59494
560 2O4C NAD 7.59494
561 1K3T BRZ 7.59494
562 5TUF TDC 7.59494
563 1ZEM NAD 7.63359
564 4RDH AMP 7.63889
565 4RDI ATP 7.63889
566 1NPD NAD 7.63889
567 2F59 INI 7.64331
568 4FOU C2E 7.69231
569 4MIG G3F 7.91139
570 5MZI FAD 7.91139
571 5MZI FYK 7.91139
572 3UZO GLU 7.91139
573 4D79 ATP 7.97101
574 2W5P CL8 8.05369
575 2BQP GLC 8.11966
576 3GRU AMP 8.13559
577 2CUL FAD 8.18966
578 4K5S FAD 8.22785
579 4K5S PM0 8.22785
580 4EUE NAI 8.22785
581 5DN9 NAD 8.22785
582 2B6N ALA PRO THR 8.27338
583 1P0F NAP 8.31099
584 3QDV NDG 8.39161
585 4URF 1PS 8.46774
586 1QXA GLY GLY GLY 8.51064
587 6AIN FAD 8.5443
588 3QVP FAD 8.5443
589 4XB2 NDP 8.5443
590 1O0S NAI 8.5443
591 4XB2 HSE 8.5443
592 2CDC NAP 8.5443
593 2CDC XYP 8.5443
594 2CDC XYS 8.5443
595 1VL0 NAI 8.56164
596 4WUJ FMN 8.84354
597 4TXI FAD 8.86076
598 1V6A TRE 8.86076
599 1LDN NAD 8.86076
600 2DBZ NAP 8.86076
601 4REP FAD 8.88889
602 2GUD MAN 9.01639
603 2GUC MAN 9.01639
604 2HYQ MAN MAN 9.01639
605 2BRY FAD 9.17722
606 4HA6 FAD 9.17722
607 3ZNN 4WL 9.17722
608 3ZNN FAD 9.17722
609 4PIV NDP 9.17722
610 4RSL FAD 9.21348
611 2F5Z FAD 9.375
612 2C7G FAD 9.49367
613 2C7G ODP 9.49367
614 3BAZ NAP 9.49367
615 4TSK NDP 9.49367
616 2HMT NAI 9.72222
617 1V59 NAD 9.81013
618 2NVK NAP 9.81013
619 1V59 FAD 9.81013
620 5C9P FUC 9.81013
621 2NVK FAD 9.81013
622 2YVJ NAI 10.0917
623 2YVJ FAD 10.0917
624 1ORR NAD 10.1266
625 1OFS SUC 10.1604
626 1HYH NAD 10.356
627 3G5S FAD 10.443
628 2ZXI FAD 10.443
629 2VVL FAD 10.443
630 6H3O FAD 10.443
631 2VVM FAD 10.443
632 3G5S GSH 10.443
633 1UXG FUM 10.6796
634 1UXG NAD 10.6796
635 1VBO MAN MAN MAN 10.7383
636 5KOX FAD 10.7595
637 6CEP NAD 10.7595
638 4M3P HCS 10.7595
639 5KOX RFP 10.7595
640 6CEP OXM 10.7595
641 3LU1 NAD 10.7595
642 5D4V SAH 10.8209
643 4II2 ATP 10.8434
644 3ICT ADP 11.0759
645 3ICS ADP 11.0759
646 5ODQ FAD 11.0759
647 3ICT FAD 11.0759
648 3LXD FAD 11.0759
649 3ICR FAD 11.0759
650 3ICS FAD 11.0759
651 1GV0 NAD 11.2903
652 1GUZ NAD 11.2903
653 5J7X FAD 11.3924
654 3NT6 FAD 11.7089
655 3NTA FAD 11.7089
656 5NMX FAD 11.7089
657 5NMX NAP 11.7089
658 3H2B SAH 11.8227
659 2O07 MTA 11.8421
660 2O07 SPD 11.8421
661 3S5W NAP 12.0253
662 3S5W FAD 12.0253
663 3H9E NAD 12.0253
664 3AYI FAD 12.0253
665 3AYI HCI 12.0253
666 3NTD FAD 12.0253
667 2BTO GTP 12.037
668 4JBI NDP 12.3418
669 4JK3 NAD 12.3552
670 5L95 AMP 12.5
671 2F1K NAP 12.5448
672 2D2I NAP 12.6582
673 3NJQ NJQ 12.9534
674 5GSN FAD 12.9747
675 5GSN NAP 12.9747
676 5EZ7 FAD 12.9747
677 5GSN MMZ 12.9747
678 1Z45 NAD 12.9747
679 2DT5 NAD 13.2701
680 1NYT NAP 13.2841
681 6ER9 FAD 13.2911
682 6ER9 NAP 13.2911
683 5TS5 FAD 13.6076
684 5EYP GTP 13.6095
685 5U5N NAD 13.6201
686 5L8L ADP 13.6752
687 1L6O SER LEU LYS LEU MET THR THR VAL 13.6842
688 5NA1 FAD 13.9241
689 3H5N ATP 13.9241
690 5EIN NAP 14.8148
691 2IID FAD 14.8734
692 2IID PHE 14.8734
693 1DJN ADP 15.5063
694 1O94 ADP 15.5063
695 3RNM FAD 15.5172
696 2AG8 NAP 15.5894
697 1ELI PYC 15.8228
698 3UOY FAD 16.1392
699 3UOY NAP 16.1392
700 3FPZ AHZ 16.7722
701 3ULK NDP 17.0886
702 5EB4 FAD 17.4051
703 5Z21 NAI 17.7215
704 1Z82 NDP 18.038
705 4AP3 NAP 18.3544
706 4AP3 FAD 18.3544
707 3UCL FAD 18.9873
708 3UCL CYH 18.9873
709 3UCL NAP 18.9873
710 1B8U NAD 18.9873
711 6HKE MLT 19.3038
712 6HKE LMR 19.3038
713 2DC1 NAD 19.9153
714 5VN0 FAD 20.2532
715 5VN0 NAI 20.2532
716 3WV8 ATP 20.6422
717 5N0J FAD 20.7977
718 3LAD FAD 21.519
719 1YY5 FAD 21.8354
720 1RSG FAD 21.8354
721 5U8U FAD 21.8354
722 1XHC FAD 22.3433
723 1Q1R FAD 23.1013
724 4JNA FAD 23.5294
725 5JWC FAD 24.0506
726 2CDU ADP 25
727 2CDU FAD 25
728 4J56 FAD 25.4386
729 2NPX FAD 25.6329
730 2NPX NAD 25.6329
731 1ZK7 FAD 26.5823
732 2HQM FAD 26.7223
733 3CGB FAD 26.8987
734 1LVL NAD 27.0742
735 1LVL FAD 27.0742
736 4EMI FAD 27.2152
737 4EMJ FAD 27.2152
738 4EMI NAD 27.2152
739 1MO9 FAD 27.2152
740 1MO9 KPC 27.2152
741 5JCM FAD 28.1596
742 5JCM NAD 28.1596
743 5JCM ISD 28.1596
744 1BZL FAD 28.1646
745 4USQ FAD 28.1646
746 1GET NAP 28.1646
747 1GET FAD 28.1646
748 1BZL GCG 28.1646
749 4USR FAD 28.481
750 2WPF FAD 28.481
751 2WPF WPF 28.481
752 1FEC FAD 29.4304
753 1YQZ FAD 29.4304
754 4BV6 FAD 29.7468
755 3QFA FAD 30.0633
756 3GD4 NAD 30.0633
757 3GD4 FAD 30.0633
758 3FG2 FAD 30.3797
759 2RAB NAD 30.6962
760 2RAB FAD 30.6962
761 3SQP FAD 31.3291
762 3KLJ FAD 33.2468
763 1REO FAD 36.7089
764 4NTD FAD 36.7647
765 5K0A FAD 39.2405
766 3AB1 FAD 39.557
767 3CGD NAD 40.5063
768 3CGD FAD 40.5063
769 3CGD COA 40.5063
770 4JDR FAD 41.7722
771 4NTC FAD 42.7215
772 5JCA FAD 42.7215
773 5JCA NDP 42.7215
774 6GAR FAD 45.2532
775 6GAS FAD 45.8861
776 4YRY NAD 46.2025
777 4YRY FAD 46.2025
778 5TWB FAD 46.519
779 3LZW FAD 46.8354
780 3LZW NAP 46.8354
781 6GNA FAD 47.9167
782 6GNC FAD 49.6599
783 5NII FAD 49.8382
Pocket No.: 2; Query (leader) PDB : 1TDF; Ligand: NAP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 1tdf.bio1) has 68 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 1TDF; Ligand: FAD; Similar sites found with APoc: 805
This union binding pocket(no: 3) in the query (biounit: 1tdf.bio1) has 47 residues
No: Leader PDB Ligand Sequence Similarity
1 1FTH A3P None
2 2Z6C FMN None
3 1QAN SAH None
4 1S8G DAO None
5 5N6C NAD 1
6 2AUY NAG MAN MMA 1.19048
7 2PHT MAN MAN MAN 1.19048
8 2GMM MAN MAN 1.19048
9 2AR6 NAG MAN 1.19048
10 2AR6 NAG MAN MAN MAN NAG 1.19048
11 1N2X SAM 1.3289
12 1X87 NAD 1.58228
13 1ZGS XMM 1.58228
14 4R5M NAP 1.58228
15 1GZ4 ATP 1.58228
16 3A27 SAM 1.58228
17 2BTM PGA 1.5873
18 5U5G NAP 1.69492
19 1RP0 AHZ 1.76056
20 1NV8 MEQ 1.76056
21 4EMV 0R9 1.76991
22 2G5C NAD 1.77936
23 2ZE3 AKG 1.81818
24 5BW4 SAM 1.87266
25 2Z3Y F2N 1.89873
26 4OPC PGT 1.89873
27 4OPC FDA 1.89873
28 4Z0H NAD 1.89873
29 4ZGS NAD 1.89873
30 1QMG APX 1.89873
31 2D3N GLC GLC GLC 1.89873
32 3E7S AT2 1.89873
33 3G1Z AMP 1.89873
34 1SZ2 BGC 1.89873
35 5KVS NAP 1.89873
36 5A1T NAI 1.89873
37 4IJP 1EH 1.89873
38 5IFK HPA 1.92308
39 4OM8 NAD 1.94175
40 1FK8 NAD 1.94553
41 3WMX NAD 1.95531
42 5D1R 56S 2.09205
43 4E13 NAD 2.12014
44 5KVA SAM 2.15827
45 5BSH PRO 2.16606
46 3FUU ADN 2.21402
47 2IVD FAD 2.21519
48 4MO2 FDA 2.21519
49 4MO2 FAD 2.21519
50 6FHO FAD 2.21519
51 3WGT QSC 2.21519
52 3WGT FAD 2.21519
53 2HJR APR 2.21519
54 1F8G NAD 2.21519
55 5UR0 NAD 2.21519
56 1GAD NAD 2.21519
57 3HDY FAD 2.21519
58 3HDY FDA 2.21519
59 3HDY GDU 2.21519
60 2YX1 SFG 2.21519
61 1L7E NAI 2.21519
62 1KGZ PRP 2.21519
63 1YKF NAP 2.21519
64 3VGL ANP 2.21519
65 1OBB NAD 2.21519
66 5Z75 NAD 2.21519
67 1WVG APR 2.21519
68 4XQC NAD 2.21519
69 4XQC 13D 2.21519
70 1ZH8 NAP 2.21519
71 2X2M X2M 2.2293
72 5XVH NAP 2.28758
73 5G6U TRP 2.29885
74 5X9D 80F 2.30263
75 1G60 SAM 2.30769
76 1YJQ NAP 2.31023
77 5OVK NDP 2.34375
78 1F28 UMP 2.3569
79 5EYW PGA 2.40964
80 3B1F NAD 2.41379
81 1FIW PBZ 2.41379
82 1NM5 NAD 2.46305
83 3X0V FAD 2.53165
84 5OC1 FAD 2.53165
85 1H82 FAD 2.53165
86 1GPE FAD 2.53165
87 2VYN NAD 2.53165
88 1H82 GZZ 2.53165
89 4AT0 FAD 2.53165
90 2JHP SAH 2.53165
91 3B20 NAD 2.53165
92 1LDM NAD 2.53165
93 3B1J NAD 2.53165
94 9LDT NAD 2.53165
95 1OMO NAD 2.53165
96 9LDB NAD 2.53165
97 1BXG NAD 2.53165
98 1YS4 NAP 2.53165
99 4E5N NAD 2.53165
100 2WHP HI6 2.53165
101 5CK5 GDP 2.53165
102 1GQ2 NAP 2.53165
103 4GPS CIT 2.53165
104 4L8V NAP 2.53165
105 6EL3 NAP 2.53165
106 3OA2 NAD 2.53165
107 1LJ8 NAD 2.53165
108 1X7D NAD 2.53165
109 4BJZ FAD 2.53165
110 4BJZ P3A 2.53165
111 6A3J NAI 2.53165
112 1BXG HCI 2.53165
113 1LLU NAD 2.53165
114 1GZ6 NAI 2.53165
115 1F8F NAD 2.53165
116 5T96 79J 2.53165
117 4GLL NAD 2.53165
118 5YAP NAI 2.53165
119 4J1Q NDP 2.53165
120 1F06 NDP 2.53165
121 5YAP 8S0 2.53165
122 1NVM NAD 2.5641
123 3WBF NAP 2.62295
124 3WBF API 2.62295
125 5ZI9 FLC 2.69231
126 1NXJ TLA 2.73224
127 3H8V ATP 2.73973
128 2DUR MAN MAN 2.7668
129 2VT3 ATP 2.7907
130 4N02 FNR 2.80112
131 3IHG FAD 2.8481
132 4FWE FAD 2.8481
133 5MBX FAD 2.8481
134 5MBX SP5 2.8481
135 1MUU NAD 2.8481
136 1WDK NAD 2.8481
137 1MV8 NAD 2.8481
138 1J0X NAD 2.8481
139 1J49 NAD 2.8481
140 4C4A SAH 2.8481
141 5CAE COA 2.8481
142 1V8B NAD 2.8481
143 5TC4 NAD 2.8481
144 1GY8 NAD 2.8481
145 2GCG NDP 2.8481
146 5AHN IMP 2.8481
147 3GON ANP 2.8481
148 1WPQ NAD 2.8481
149 4LYA ATP 2.8481
150 4EIL UMP 2.8481
151 1HDR NAD 2.86885
152 2OOR NAD 2.87356
153 2BGM NAJ 2.8777
154 3A1I UNU 2.87908
155 1DCP HBI 2.88462
156 1P77 ATR 2.94118
157 6AA8 NAD 2.98013
158 5NM7 GLY 3.00752
159 5GT9 NAP 3.04183
160 5Y8L HUI 3.05085
161 5Y8L NAD 3.05085
162 3ZYR ASN NAG NAG BMA MAN MAN NAG NAG 3.06513
163 2RBK VN4 3.06513
164 2PWY SAH 3.10078
165 3M6P BB2 3.10881
166 2Q46 NAP 3.16206
167 5UAO FAD 3.16456
168 4IV9 FAD 3.16456
169 5EOW FAD 3.16456
170 4J36 FAD 3.16456
171 3Q9T FAY 3.16456
172 4J36 1HR 3.16456
173 3AXB PRO 3.16456
174 3AXB FAD 3.16456
175 1LTH NAD 3.16456
176 4D7E FAD 3.16456
177 3NYC IAR 3.16456
178 3NYC FAD 3.16456
179 5Y77 FAD 3.16456
180 6C4N NAP 3.16456
181 3V1Y NAD 3.16456
182 5LD5 NAD 3.16456
183 2V6G NAP 3.16456
184 3NJ4 NAD 3.16456
185 6C4M NAP 3.16456
186 3M89 GSP 3.16456
187 2PT9 S4M 3.16456
188 6BQ6 TER 3.16456
189 3HIY UTP 3.16456
190 5KOD AMP 3.16456
191 3DAG FEG 3.16456
192 4DPL NAP 3.16456
193 4PLT OXM 3.16456
194 4PLT NAI 3.16456
195 5Y80 IRE 3.19489
196 1O8B ABF 3.19635
197 1M0S CIT 3.19635
198 1I9G SAM 3.21429
199 3VPH NAD 3.22581
200 3VPH OXM 3.22581
201 3OFK SAH 3.24074
202 4CQM NAP 3.27869
203 5JE8 NAD 3.31126
204 3G2O SAM 3.34448
205 3RFV 15L 3.37079
206 1C3X 8IG 3.38346
207 1JG3 ADN 3.40426
208 2IOR ADP 3.40426
209 5OCM NAP 3.43643
210 5N2I NAP 3.44828
211 3ESS 18N 3.47826
212 5ZYN FAD 3.48101
213 2XVF FAD 3.48101
214 4U8P FDA 3.48101
215 4U8P UDP 3.48101
216 2RGH FAD 3.48101
217 4EIP K2C 3.48101
218 4EIP FAD 3.48101
219 1Y8Q ATP 3.48101
220 1X14 NAD 3.48101
221 4MOP 2H5 3.48101
222 3K5I AIR 3.48101
223 1CF2 NAP 3.48101
224 1RM4 NDP 3.48101
225 6C4T NA7 3.48101
226 5SXS NIZ 3.48101
227 2XVE FAD 3.48101
228 4XDY NAI 3.48101
229 1YKJ PHB 3.48101
230 1YKJ FAD 3.48101
231 4LWP SAH 3.48101
232 2YYY NAP 3.48101
233 1T9D P22 3.48101
234 2PK3 A2R 3.48101
235 2IXB NAD 3.48101
236 4KVL PLM 3.48101
237 3ZL8 ADP 3.48101
238 4GKV NAD 3.48101
239 3CB2 GDP 3.48101
240 5G4L NDP 3.4965
241 1HYE NAP 3.51438
242 1P1C SAH 3.51759
243 2I7C AAT 3.53357
244 3KVY URA 3.55987
245 4RDL FUC GAL NDG FUC 3.57143
246 4YCA NDP 3.7415
247 2FMD MAN MAN 3.75
248 2QA1 FAD 3.79747
249 3E1T FAD 3.79747