Receptor
PDB id Resolution Class Description Source Keywords
1D8T 2.35 Å EC: 3.6.1.48 CRYSTAL STRUCTURE OF ELONGATION FACTOR, TU (EF-TU-MGGDP) COM WITH GE2270A, A THIAZOLYL PEPTIDE ANTIBIOTIC ESCHERICHIA COLI HYDROLASE-ANTIBIOTIC COMPLEX THIOPEPTIDE ANTIBIOTIC ANTIBTHIAZOLE OXAZOLE HYDROLASE GTPASE TRANSLATION ELONGATIOPROTEIN SYNTHESIS NUCLEOTIDE-BINDING PHOSPHORYLATION
Ref.: STRUCTURE OF AN EF-TU COMPLEX WITH A THIAZOLYL PEPT ANTIBIOTIC DETERMINED AT 2.35 A RESOLUTION: ATOMIC GE2270A INHIBITION OF EF-TU. BIOCHEMISTRY V. 39 37 2000
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ACT A:3002;
A:3003;
A:3004;
A:3005;
A:3006;
A:3007;
A:3010;
A:3013;
A:3016;
A:3017;
A:3019;
A:3020;
A:3021;
A:3022;
A:3023;
A:3025;
A:3026;
A:3028;
A:3030;
B:3001;
B:3008;
B:3009;
B:3011;
B:3012;
B:3014;
B:3015;
B:3018;
B:3024;
B:3027;
B:3029;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
59.044 C2 H3 O2 CC(=O...
GDP A:999;
B:999;
Valid;
Valid;
none;
none;
submit data
443.201 C10 H15 N5 O11 P2 c1nc2...
MG A:998;
B:998;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1D8T 2.35 Å EC: 3.6.1.48 CRYSTAL STRUCTURE OF ELONGATION FACTOR, TU (EF-TU-MGGDP) COM WITH GE2270A, A THIAZOLYL PEPTIDE ANTIBIOTIC ESCHERICHIA COLI HYDROLASE-ANTIBIOTIC COMPLEX THIOPEPTIDE ANTIBIOTIC ANTIBTHIAZOLE OXAZOLE HYDROLASE GTPASE TRANSLATION ELONGATIOPROTEIN SYNTHESIS NUCLEOTIDE-BINDING PHOSPHORYLATION
Ref.: STRUCTURE OF AN EF-TU COMPLEX WITH A THIAZOLYL PEPT ANTIBIOTIC DETERMINED AT 2.35 A RESOLUTION: ATOMIC GE2270A INHIBITION OF EF-TU. BIOCHEMISTRY V. 39 37 2000
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 1D8T - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 1D8T - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 1D8T - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GDP; Similar ligands found: 153
No: Ligand ECFP6 Tc MDL keys Tc
1 GDP 1 1
2 GTP 0.909091 1
3 GP3 0.881579 0.973684
4 GNH 0.858974 0.986667
5 GNP 0.839506 0.973684
6 G 0.828947 0.986486
7 5GP 0.828947 0.986486
8 G1R 0.82716 0.986667
9 GCP 0.82716 0.973684
10 GSP 0.817073 0.948718
11 GAV 0.797619 0.961039
12 GMV 0.792683 0.973684
13 G2P 0.77381 0.961039
14 G2R 0.770115 0.961039
15 GDP MG 0.759036 0.923077
16 GP2 0.756098 0.961039
17 GDP BEF 0.75 0.9
18 GDD 0.747253 0.961039
19 GKE 0.747253 0.961039
20 GDC 0.747253 0.961039
21 GPG 0.741573 0.961039
22 G3D 0.732558 0.986486
23 ALF 5GP 0.729412 0.888889
24 Y9Z 0.728261 0.902439
25 GTP MG 0.724138 0.923077
26 BEF GDP 0.724138 0.888889
27 G5P 0.723404 0.973684
28 GFB 0.72043 0.961039
29 GTG 0.72043 0.936709
30 GDR 0.72043 0.961039
31 G4P 0.715909 0.986486
32 GCP G 0.715909 0.935065
33 6CK 0.712766 0.936709
34 G3A 0.712766 0.973684
35 GDP ALF 0.7 0.888889
36 GDP AF3 0.7 0.888889
37 YGP 0.698925 0.901235
38 JB2 0.697917 0.961039
39 GKD 0.697917 0.961039
40 GDX 0.690722 0.973684
41 GPD 0.690722 0.925
42 GMP 0.684211 0.88
43 0O2 0.666667 0.986486
44 G G 0.659574 0.935065
45 JB3 0.656863 0.948718
46 NGD 0.650485 0.961039
47 GDP 7MG 0.636364 0.911392
48 DGI 0.636364 0.923077
49 U2G 0.634615 0.936709
50 GPX 0.634409 0.946667
51 IDP 0.632184 0.972973
52 2MD 0.632075 0.891566
53 CAG 0.62963 0.880952
54 CG2 0.622642 0.936709
55 FEG 0.619048 0.879518
56 MGD 0.614679 0.891566
57 ZGP 0.613208 0.869048
58 GH3 0.612903 0.973333
59 3GP 0.611765 0.946667
60 MD1 0.607143 0.891566
61 PGD 0.59292 0.925
62 DGT 0.591398 0.923077
63 BGO 0.588785 0.924051
64 TPG 0.582609 0.840909
65 DBG 0.582609 0.948718
66 2GP 0.574713 0.96
67 FE9 0.570175 0.776596
68 I2C FE2 CMO CMO 0.566372 0.808989
69 G A A A 0.553571 0.923077
70 MGP 0.553191 0.961039
71 U A G G 0.548673 0.935065
72 G4M 0.548387 0.880952
73 6G0 0.547368 0.961039
74 G1R G1R 0.542373 0.924051
75 P2G 0.527473 0.883117
76 PGD O 0.525 0.850575
77 ADP 0.522222 0.92
78 GGM 0.517544 0.901235
79 DG 0.516484 0.910256
80 DGP 0.516484 0.910256
81 P1G 0.516129 0.871795
82 G G U 0.509259 0.935065
83 G1G 0.508475 0.925
84 IMP 0.505495 0.959459
85 G C 0.504348 0.9
86 GPC 0.491525 0.879518
87 G7M 0.483871 0.948052
88 6AD 0.479592 0.841463
89 ATP 0.473684 0.92
90 G2Q 0.471154 0.961039
91 U G A 0.469697 0.888889
92 5FA 0.46875 0.92
93 AQP 0.46875 0.92
94 GTA 0.468468 0.936709
95 7DD 0.468085 0.906667
96 G G G RPC 0.466102 0.875
97 SGP 0.463158 0.82716
98 01G 0.462963 0.902439
99 B4P 0.457447 0.894737
100 AP5 0.457447 0.894737
101 A2D 0.456522 0.894737
102 G G G C 0.455285 0.9125
103 ACQ 0.454545 0.896104
104 5GP 5GP 0.454545 0.883117
105 ANP 0.454545 0.896104
106 A G C C 0.451613 0.911392
107 APC G U 0.45082 0.886076
108 G U34 0.449153 0.888889
109 DG DG 0.448598 0.865854
110 ITT 0.447917 0.868421
111 BA3 0.446809 0.894737
112 35G 0.444444 0.933333
113 C2E 0.444444 0.921053
114 PCG 0.444444 0.933333
115 MGO 0.441176 0.864198
116 AN2 0.4375 0.907895
117 G C C C 0.4375 0.924051
118 M33 0.43299 0.883117
119 UCG 0.429688 0.911392
120 A G U 0.42963 0.888889
121 ACP 0.428571 0.896104
122 MGQ 0.424528 0.935897
123 7DT 0.424242 0.906667
124 APR 0.424242 0.894737
125 AR6 0.424242 0.894737
126 93A 0.42268 0.833333
127 A4P 0.420168 0.869048
128 SAP 0.42 0.873418
129 AD9 0.42 0.896104
130 AGS 0.42 0.873418
131 G8D 0.42 0.875
132 CA0 0.418367 0.896104
133 ATF 0.417476 0.884615
134 AGO 0.414634 0.888889
135 NIA 0.413043 0.82716
136 MGV 0.412844 0.890244
137 TAT 0.411765 0.884615
138 A1R 0.411215 0.839506
139 ADQ 0.411215 0.871795
140 RGT 0.410714 0.909091
141 CGP 0.409836 0.86747
142 AMP 0.408602 0.893333
143 A 0.408602 0.893333
144 UP5 0.40678 0.873418
145 C2R 0.406593 0.906667
146 AMZ 0.406593 0.918919
147 JBT 0.405882 0.778947
148 A22 0.40566 0.907895
149 25L 0.405405 0.907895
150 ADX 0.40404 0.809524
151 8OD 0.401961 0.946667
152 4TC 0.4 0.851852
153 50T 0.4 0.883117
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1D8T; Ligand: GDP; Similar sites found: 520
This union binding pocket(no: 1) in the query (biounit: 1d8t.bio2) has 16 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1EK0 GNP 0.000000001978 0.54504 None
2 1D5C GDP 0.00000000006246 0.68447 1.23457
3 1YTM ATP 0.00005031 0.44436 1.27226
4 2F3R G5P 0.01613 0.41781 1.27226
5 4B9E FAH 0.0178 0.40746 1.3289
6 2WKQ GTP 0.00000002618 0.53775 1.50602
7 5TSH ADP 0.00005272 0.52775 1.52672
8 1V8K ANP 0.00002617 0.52166 1.52672
9 5TSH ANP 0.00003161 0.51784 1.52672
10 5XDR ADP 0.0003895 0.45593 1.52672
11 4FCW ADP 0.0001567 0.48844 1.60772
12 1Z0F GDP 0.00000000002022 0.77621 1.67598
13 2GWH A3P 0.002203 0.4006 1.67785
14 3LRE ADP 0.0000002659 0.661 1.69014
15 3ZS9 ADP ALF 0.00001246 0.42582 1.69492
16 2WOJ ADP ALF 0.00001514 0.42386 1.69492
17 2G77 GDP 0.00000000002535 0.69865 1.78117
18 5LB3 ADP 0.0002004 0.48694 1.78117
19 2XAU ADP 0.0003366 0.47557 1.78117
20 5HR5 ADP 0.00007658 0.45204 1.78117
21 2G77 AF3 0.006659 0.42397 1.78117
22 1P9B GDP 0.000004118 0.50443 1.80995
23 4ZNL BEF ADP 0.00002255 0.50976 1.82482
24 1NST A3P 0.0009184 0.45972 1.84615
25 1TAD ALF 0.000000001725 0.5207 1.85185
26 1TAD GDP 0.000000001725 0.5207 1.85185
27 1U0J ADP 0.0003472 0.47552 1.87266
28 5L3W GDP 0.000001714 0.54765 1.96078
29 2F9L GDP 0.0000000002843 0.59686 2.01005
30 3IO3 ADP 0.000009778 0.55697 2.01149
31 5IRN ADP 0.00001616 0.49021 2.03562
32 1XKV ATP 0.000079 0.47472 2.03562
33 5VGR GDP 0.00008029 0.45303 2.03562
34 1OIV GDP 0.000000000285 0.7931 2.09424
35 1OIX GDP 0.000000000349 0.56788 2.09424
36 1G6O ADP 0.00007527 0.4734 2.12121
37 1MH1 GNP 0.00000001744 0.51011 2.15054
38 1G4U GDP 0.00000002743 0.57541 2.17391
39 4LX0 BEF GDP 0.0000000004545 0.78617 2.25989
40 3NHB ADP 0.000009024 0.56778 2.29008
41 3DEF GDP 0.000001186 0.53735 2.29008
42 2VVG ADP 0.0000001256 0.53591 2.29008
43 2DPY ADP 0.00005437 0.52175 2.29008
44 4A4Z ANP 0.001674 0.43747 2.29008
45 1K6M AGS 0.0001284 0.41121 2.29008
46 1VHT BA3 0.0001535 0.46626 2.29358
47 5HCN GCP 0.000000001633 0.69488 2.29885
48 4LHW GNP 0.00000000108 0.55285 2.29885
49 4KFU ACP 0.000002485 0.52811 2.35849
50 4R2I ANP 0.0008667 0.46259 2.38095
51 2D7C GTP 0.000000000321 0.56835 2.39521
52 3BER AMP 0.008174 0.40531 2.40964
53 3FIU POP 0.01701 0.40081 2.40964
54 3DZD ADP 0.0006557 0.42962 2.44565
55 1R0X ATP 0.0002099 0.46992 2.44755
56 2ZFI ADP 0.00001429 0.53392 2.45902
57 3ZQ6 ADP ALF 0.00000997 0.42768 2.46914
58 4LPS GDP 0.00000002078 0.64441 2.47934
59 4P4T GDP 0.0000000472 0.56646 2.5
60 3FVQ ATP 0.0002961 0.41318 2.50696
61 5KSZ GCP 0.0000002071 0.58596 2.54453
62 4HSE ADP 0.00006495 0.48918 2.54453
63 1IHU AF3 0.000003396 0.47141 2.54453
64 1IHU ADP 0.000003824 0.46047 2.54453
65 1OYY AGS 0.008193 0.40526 2.54453
66 5K5Z ANP 0.0002008 0.40565 2.54777
67 5BQ5 ADP BEF 0.000092 0.47208 2.6455
68 1CR1 TTP 0.00007977 0.51544 2.7027
69 2Y8E GNP 0.0000000003682 0.56914 2.7933
70 2QTV GNP 0.0000000109 0.71204 2.79898
71 1G41 ADP 0.00006639 0.47792 2.79898
72 2VF7 ADP 0.0001943 0.46892 2.79898
73 2C9O ADP 0.00008599 0.43477 2.79898
74 5J1J ANP 0.00001115 0.44834 2.80702
75 4TMK T5A 0.009186 0.43147 2.8169
76 4BQS ADP 0.00002246 0.52476 2.84091
77 4PPF FLC 0.000001567 0.61536 2.85714
78 2ZR9 DTP 0.0000452 0.5106 2.86533
79 4WEI GLC GAL 0.02546 0.40028 2.88809
80 3QXC ATP 0.00008005 0.40204 2.89256
81 2FFQ GSP 0.0000000003066 0.79465 2.92398
82 1YZQ GNP 0.0000000001753 0.56386 2.94118
83 1R2Q GNP 0.0000000003602 0.49086 2.94118
84 3MJH GTP 0.0000000001159 0.57919 2.97619
85 1RRC ADP 0.00000565 0.49377 2.99003
86 3Q72 GNP 0.00000000006105 0.76305 3.01205
87 1OE0 TTP 0.003817 0.44254 3.04348
88 1GOT GDP 0.000000002225 0.58744 3.05344
89 5I0H ADP BEF 0.0001453 0.50283 3.05344
90 3EZ2 ADP 0.0001255 0.49667 3.05344
91 4IHQ ADP 0.0001076 0.48294 3.05344
92 5MZN ADP 0.0007582 0.46545 3.05344
93 4YS0 ADP 0.001098 0.41434 3.05344
94 1GOJ ADP 0.0000001196 0.68046 3.09859
95 2XTZ GSP 0.0000000005068 0.56647 3.10734
96 3ZFD ANP 0.00002837 0.52638 3.1339
97 3CPJ GDP 0.0000000002797 0.76757 3.13901
98 3VX3 ADP 0.00007932 0.44893 3.22581
99 4DKX GDP 0.00000000001415 0.81376 3.24074
100 2FH5 GTP 0.0000000001301 0.63795 3.24324
101 4LYA ATP 0.000008553 0.529 3.30789
102 4PFO ADP 0.0001661 0.50827 3.30789
103 2OBM ADP 0.0006573 0.47648 3.30789
104 4XGU ADP 0.00005228 0.46308 3.30789
105 4PJ3 ANP 0.001727 0.41304 3.30789
106 1UH4 GLC GLC GLC GLC GLC GLC 0.0078 0.41195 3.30789
107 2OZE AGS 0.0003543 0.42052 3.3557
108 2FNA ADP 0.000006835 0.45899 3.36134
109 1JJV ATP 0.00001313 0.55717 3.39806
110 5X40 ACP 0.0003443 0.48881 3.42466
111 1T5C ADP 0.0000002415 0.66624 3.4384
112 3B7G ANP 0.0003634 0.45867 3.47826
113 3UIE ANP 0.0000255 0.49461 3.5
114 4GOX A3P 0.00009403 0.4198 3.51438
115 2ZE7 DST 0.004658 0.43824 3.55731
116 1W0J ADP 0.000006642 0.5593 3.56234
117 2ZPA ADP 0.0001483 0.50007 3.56234
118 1W0J ADP BEF 0.0002159 0.49222 3.56234
119 3TBK ANP 0.0009568 0.46047 3.56234
120 2CK3 ANP 0.0002445 0.4258 3.56234
121 3CV2 OXL 0.01511 0.40353 3.56234
122 5XQL C2E 0.02478 0.40106 3.56234
123 2CK3 ADP 0.0002882 0.4008 3.56234
124 5AHO TLA 0.009201 0.42121 3.57143
125 5G41 AP5 0.001476 0.48454 3.58744
126 1KAO GDP 0.0000000003439 0.6564 3.59281
127 3H86 AP5 0.0002183 0.51549 3.64583
128 4XTR ADP 0.00000765 0.48256 3.68664
129 4XTR ATP 0.00001095 0.44959 3.68664
130 4XVU ATP 0.00001426 0.44667 3.68664
131 5UQW GDP 0.0000000001633 0.58747 3.7037
132 4JLV ADP 0.0001036 0.48412 3.71747
133 2ZPT A3P 0.0145 0.43874 3.72881
134 3WYF GTP 0.000000001768 0.75973 3.78151
135 4D0N GDP 0.000000003349 0.7031 3.78378
136 4WZ6 ATP 0.00001347 0.55883 3.7931
137 1TU3 GNP 0.00000000009622 0.58142 3.79747
138 1KMQ GNP 0.00000003605 0.53321 3.80435
139 2BCG GDP 0.0000000001311 0.65354 3.81679
140 1Z06 GNP 0.0000000001015 0.59495 3.81679
141 2BIF SIN 0.0003667 0.51404 3.81679
142 2BIF ANP 0.0002182 0.51404 3.81679
143 5IFS ADP 0.00008856 0.503 3.81679
144 1R6B ADP 0.0001038 0.48157 3.81679
145 3FKQ ATP 0.00001801 0.4812 3.81679
146 1JJ7 ADP 0.000001162 0.62978 3.84615
147 5GVR LMR 0.001031 0.45065 3.84615
148 1FNN ADP 0.0001663 0.43294 3.85604
149 1MR3 G3D 0.00000000002747 0.80569 3.8674
150 5M04 GDP 0.000000000004385 0.85352 3.88889
151 4XOI GTP 0.00000005361 0.51766 3.88889
152 1TX4 ALF GDP 0.00000006791 0.52647 3.9548
153 3ZIA ATP 0.00001338 0.52024 3.95683
154 3ZIA ADP 0.00001287 0.49465 3.95683
155 2EW1 GNP 0.0000000006481 0.76903 3.9801
156 2ZTS ADP 0.0001421 0.43101 3.98406
157 4D0G GTP 0.00000000007973 0.62639 4
158 2AWN ADP 0.0000004931 0.65439 4.07125
159 3DC4 ADP 0.00001765 0.54579 4.07125
160 2FAH GDP 0.00003327 0.48167 4.07125
161 2FSH ANP 0.002513 0.42251 4.07125
162 4AG5 ADP 0.00000728 0.57238 4.08163
163 2Q2Y ADP 0.0001598 0.52919 4.08719
164 2Q2Y MKR 0.0001579 0.52816 4.08719
165 3QF7 ANP 0.0001972 0.49412 4.10959
166 1ION ADP 0.00001711 0.5032 4.11523
167 3BOS CDP 0.00002021 0.52689 4.13223
168 3Q85 GNP 0.000000000003552 0.84174 4.14201
169 3TNF GNP 0.0000000004374 0.78996 4.16667
170 2GDJ ANP 0.0001828 0.48232 4.16667
171 5E5U MLI 0.006142 0.40527 4.16667
172 4HDO GNP 0.000000001413 0.5396 4.19162
173 3X1Z GNP 0.000000001655 0.5277 4.19162
174 4YC7 GNP 0.00000001571 0.69818 4.19948
175 1O3Y GTP 0.000000000164 0.60396 4.21687
176 2J59 GTP 0.0000000002539 0.5985 4.21687
177 1J2J GTP 0.000000001013 0.5811 4.21687
178 1G3Q ADP 0.000006408 0.53439 4.21941
179 4GOJ GNP 0.000000000009627 0.85462 4.2328
180 2X77 GDP 0.0000000003152 0.72538 4.2328
181 2J0V GDP 0.000000002256 0.7158 4.24528
182 3QBT GNP 0.0000000004127 0.5647 4.28571
183 5WRJ A3P 0.0007044 0.47547 4.29043
184 5IRC GDP 0.0000001186 0.59455 4.30108
185 3RWO GDP 0.0000000002432 0.79651 4.32432
186 4ZG4 VO4 ADP 0.0001247 0.40965 4.3257
187 3AQ4 GDP 0.00000000001527 0.78183 4.34783
188 5L3V GDP 0.0000002919 0.57879 4.34783
189 5L3S GNP 0.0000008076 0.48086 4.36242
190 2HF9 GSP 0.00000005441 0.57998 4.42478
191 2CHG ANP 0.00008516 0.45216 4.42478
192 1RYH GNP 0.000000002584 0.71744 4.4335
193 4PX9 ADP 0.0001016 0.50105 4.45205
194 2GCN GDP 0.00000001585 0.69799 4.47761
195 2GCO GNP 0.00000001711 0.59618 4.47761
196 4U00 ADP 0.000002401 0.60988 4.5082
197 5HGZ ACO 0.01783 0.40775 4.52675
198 4ZI2 GNP 0.000000000009187 0.65758 4.58015
199 1XMV ADP 0.0000305 0.50324 4.58015
200 5LTJ ADP 0.0001273 0.47657 4.58015
201 4NON GDP 0.000000001968 0.52656 4.61538
202 3Q9L ATP 0.0001413 0.44412 4.61538
203 4KBF AMP 0.00183 0.44096 4.65753
204 4FRZ ADP 0.000002032 0.52935 4.66321
205 4V03 ADP 0.000009725 0.51224 4.66926
206 1Z08 GNP 0.000000001161 0.57862 4.70588
207 1J99 AND 0.008198 0.43399 4.77816
208 2PZE ATP 0.000004111 0.4995 4.80349
209 1VG8 GNP 0.0000000002127 0.80253 4.83092
210 1VG0 GDP 0.00000000006749 0.79696 4.83092
211 3N5C GDP 0.00000000001821 0.80866 4.83461
212 2A5F GTP 0.0000000002053 0.58842 4.83461
213 1NY5 ADP 0.0004594 0.4242 4.83461
214 4XFR CIT 0.01091 0.41118 4.83461
215 3COB ADP 0.0000003137 0.5417 4.87805
216 2IYL GDP 0.000001 0.58774 4.92958
217 1KY3 GDP 0.0000000004136 0.75948 4.94506
218 2W58 ADP 0.000003459 0.60129 4.9505
219 1RE0 GDP 0.000000000003473 0.81758 4.97738
220 5H67 ATP 0.005279 0.40484 5
221 4LJ9 ACP 0.0002887 0.47307 5.01475
222 4M9Q GNP 0.00000000001728 0.64881 5.08906
223 2ZEJ GDP 0.0000000009945 0.54176 5.08906
224 1W5T ADP 0.0009578 0.41315 5.08906
225 1W5T ANP 0.0004432 0.41067 5.08906
226 3FB4 AP5 0.0008375 0.49196 5.09259
227 4TTQ ATP 0.00004825 0.50928 5.11628
228 3KJI ADP 0.00001134 0.54824 5.11811
229 1KO8 6PG 0.0002151 0.4923 5.14286
230 1H65 GDP 0.000003602 0.47631 5.18518
231 2D2F ADP 0.0001193 0.52112 5.2
232 2V5K OXM 0.009699 0.41959 5.22648
233 5KSP GDP 0.0000000377 0.63373 5.26316
234 4YDS ATP 0.00001573 0.54824 5.26316
235 5KUT GDP 0.000000003932 0.70447 5.29101
236 4DSU GDP 0.000000000297 0.55537 5.29101
237 5JCZ GDP 0.0000000007973 0.62426 5.34351
238 2NCD ADP 0.000002334 0.59726 5.34351
239 4R43 GDP 0.00002282 0.52444 5.34351
240 5FTB ANP 0.0001745 0.45957 5.34351
241 5FHD ADP ALF 0.0001337 0.42418 5.34351
242 4IDN GNP 0.0001003 0.42335 5.34351
243 3BD9 A3P 0.004141 0.41132 5.35714
244 1IN4 ADP 0.00005879 0.44779 5.38922
245 1VG1 GDP 0.00000000001054 0.82524 5.40541
246 1VG9 GDP 0.00000000004631 0.79505 5.40541
247 1UKZ ADP 0.0005719 0.49279 5.41872
248 1CJW COT 0.01918 0.41027 5.42169
249 1XP8 AGS 0.00004541 0.5178 5.46448
250 4XSH GSP 0.00000001764 0.58087 5.47945
251 2CBZ ATP 0.000001149 0.6288 5.48523
252 4MKG AP5 0.0006043 0.4993 5.52995
253 3T1O GDP 0.0000000003181 0.76046 5.55556
254 5MVR ADP 0.000009842 0.54146 5.55556
255 1UJ2 ADP 0.00004951 0.40132 5.55556
256 1WF3 GNP 0.000000000533 0.78273 5.59796
257 1SVK ALF GDP 0.000000001534 0.76821 5.59796
258 5KDO GDP 0.00000000232 0.60233 5.59796
259 1JWY GDP 0.00000004789 0.59597 5.59796
260 1GP2 GDP 0.00000000177 0.57796 5.59796
261 1JWY ADP 0.00006018 0.4906 5.59796
262 3BFX A3P 0.0005841 0.4154 5.59796
263 3PCR GTP 0.0000000001712 0.60387 5.60224
264 3E5H GNP 0.000000002273 0.54723 5.61798
265 1XTQ GDP 0.0000000001742 0.79695 5.64972
266 3REF GDP 0.00000001843 0.55051 5.6701
267 1YRB GDP 0.0000000000412 0.71215 5.72519
268 3LXR GDP 0.000000005999 0.64787 5.72917
269 2BEK ATP 0.0003917 0.4068 5.83658
270 5IRR GSP 0.000001583 0.49376 5.84416
271 5XCO GDP 0.0000000001278 0.69364 5.84795
272 5M7P ADP 0.0001466 0.43291 5.85242
273 2IXE ATP 0.0002129 0.40892 5.85242
274 2BME GNP 0.0000000006022 0.77705 5.91398
275 1YZN GNP 0.0000000004273 0.55322 5.94595
276 1BO4 COA 0.00459 0.41703 5.95238
277 1Y63 ADP 0.000004201 0.55869 5.97826
278 4MKF AP5 0.0007095 0.49685 5.99078
279 1BH2 GSP 0.000000006444 0.50994 6.03175
280 3FWY ADP 0.0000009195 0.5252 6.05096
281 1TQ4 GDP 0.000000001117 0.60526 6.05327
282 5GOE GDP 0.00000000002233 0.74514 6.10687
283 4WZA ADP 0.00007986 0.56424 6.10687
284 4WZA ACP 0.00008104 0.5639 6.10687
285 5I34 GDP 0.000001685 0.56094 6.10687
286 3T34 GDP 0.000001172 0.4869 6.10687
287 3RC3 ANP 0.002763 0.43239 6.10687
288 3DKP ADP 0.0002871 0.47318 6.12245
289 3IUY AMP 0.01001 0.40118 6.14035
290 4U5X GNP 0.00000001526 0.58067 6.17978
291 1M2O GNP 0.000000003408 0.73987 6.31579
292 2PL3 ADP 0.0003751 0.47391 6.35593
293 4YLG GDP 0.00000000002594 0.6975 6.35838
294 1FP6 ADP 0.000005397 0.50806 6.36132
295 1Z6T ADP 0.0001286 0.44279 6.36132
296 4IEE AGS 0.001745 0.44195 6.36132
297 4K81 GTP 0.000000001176 0.53249 6.43275
298 4QM7 GTP 0.00007802 0.49955 6.43275
299 4V0K GDP 0.0000000001569 0.59136 6.50888
300 5E95 GDP 0.0000000003282 0.65822 6.54762
301 1GXU 2HP 0.001597 0.43225 6.59341
302 3KUD GDP 0.0000000003627 0.6208 6.62651
303 1WQ1 GDP 0.000000000597 0.5838 6.62651
304 1NVU GTP 0.0000000007248 0.54537 6.62651
305 1NVV GNP 0.0000000008958 0.54339 6.62651
306 3DDC GNP 0.0000000009119 0.54323 6.62651
307 1CLU DBG 0.000000002404 0.43016 6.62651
308 1JI0 ATP 0.00002463 0.53866 6.66667
309 3H4S ADP 0.000000528 0.53329 6.66667
310 4WOP CTP 0.0007603 0.40363 6.66667
311 2OG2 MLI 0.000009084 0.60349 6.68524
312 2VB6 ADP BEF 0.0001555 0.40719 6.71141
313 2C5L GTP 0.0000000004062 0.55358 6.83761
314 2Y65 ADP 0.0000002576 0.54521 6.84932
315 3AB3 GDP 0.0000000004067 0.77182 6.87023
316 1ZCB GDP 0.000000001002 0.76613 6.87023
317 3CX8 GSP 0.000000001271 0.52798 6.87023
318 1F9V ADP 0.000002996 0.52283 6.87023
319 2C04 GCP 0.000006992 0.50051 6.87023
320 1S9D GDP 0.00000000001637 0.78059 6.89655
321 5O2T GSP 0.000000000452 0.55275 6.95187
322 4OI4 ATP 0.0001425 0.4096 6.95652
323 2XT3 ADP 0.0000006118 0.63399 6.97674
324 2GJ8 ALF GDP 0.00000000002015 0.58762 6.97674
325 3MD0 GDP 0.00000000000633 0.84589 7.04225
326 1OXV ANP 0.00003706 0.52203 7.08215
327 2RCN GDP 0.00000000006813 0.78195 7.12468
328 3P4X ADP 0.00005143 0.49751 7.12468
329 4QOS ADP 0.0002084 0.45612 7.12468
330 1XPJ TLA 0.01593 0.41663 7.12468
331 1FZQ GDP 0.000000000002785 0.84667 7.18232
332 2EFE GNH 0.000000000198 0.68747 7.18232
333 5SZH GNP 0.0000000002361 0.55788 7.38916
334 4LC1 GDP 0.0000000001364 0.7679 7.4184
335 4D81 ADP 0.00006426 0.46721 7.42049
336 3RLF ANP 0.0002468 0.40143 7.43243
337 1ZJ6 G3D 0.00000000000476 0.80371 7.48663
338 2D7D ADP 0.001961 0.43427 7.5
339 2W2X GSP 0.000000007759 0.70979 7.56757
340 2V7Q ATP 0.000006743 0.51879 7.57576
341 2V7Q ADP 0.000172 0.48355 7.57576
342 3E70 GDP 0.0000006191 0.58088 7.62195
343 1YVD GNP 0.000000000448 0.56513 7.69231
344 1OW3 GDP 0.00000001876 0.68433 7.77202
345 2HV8 GTP 0.000000000628 0.77615 7.8125
346 3TK1 GDP 0.000000000005616 0.8654 7.87879
347 2IS6 ADP 0.0001089 0.4928 7.88804
348 3B9Q MLI 0.000007355 0.58216 7.94702
349 1BG2 ADP 0.00000006607 0.54491 8
350 1B0U ATP 0.0001933 0.44607 8.01527
351 1AQU A3P 0.001708 0.4468 8.08081
352 1YQT ADP 0.00001218 0.56115 8.14249
353 3TKL GTP 0.0000000002189 0.58378 8.16327
354 1FQK GDP 0.000000002494 0.57374 8.16327
355 5L3R GCP 0.0000008769 0.48021 8.19113
356 1GWN GTP 0.00000001237 0.69998 8.29268
357 1I4D GDP 0.000000001864 0.72773 8.33333
358 1DS6 GDP 0.00000000179 0.71578 8.33333
359 1E96 GTP 0.00000003884 0.51195 8.37438
360 3M1I GTP 0.000000001478 0.76075 8.37696
361 2KIN ADP 0.00000009729 0.53892 8.40336
362 4C4P GNP 0.0000000002796 0.79663 8.41121
363 1PUJ GNP 0.00000000005412 0.80152 8.51064
364 4HI0 GDP 0.00000002836 0.56456 8.54271
365 3SBD GNP 0.00000003677 0.51217 8.55615
366 1Z0K GTP 0.0000000003115 0.59511 8.72093
367 3SFV GDP 0.0000000002415 0.78279 8.83978
368 3A4M ADP 0.00000279 0.58519 8.84615
369 4DCT GDP 0.00000000001194 0.78691 8.90585
370 1S8F GDP 0.0000000003349 0.54396 8.90585
371 1YZG GDP 0.000000000004027 0.84486 8.93855
372 2XTN GTP 0.00000162 0.48166 8.97436
373 2FJU GSP 0.00000001761 0.69254 8.98876
374 3B5J 12D 0.0000475 0.52463 9.0535
375 1R4A GNP 0.00000000007899 0.5986 9.09091
376 1HE1 GDP 0.00000001387 0.57093 9.09091
377 1LVG ADP 0.0000006889 0.56571 9.09091
378 4GDX GLU 0.004219 0.4367 9.23077
379 4P32 ADP 0.0002594 0.40638 9.23695
380 1M7B GTP 0.000000006671 0.5814 9.23913
381 2GK6 ADP 0.0009248 0.4612 9.41476
382 2QEN ADP 0.00001078 0.55219 9.42857
383 3IIJ ADP 0.00001011 0.54091 9.44444
384 1HTW ADP 0.00001041 0.54374 9.49367
385 2PEZ DAT 0.0000515 0.54427 9.49721
386 3BFV ADP 0.000006244 0.55067 9.5941
387 1B7T ADP 0.0001123 0.46684 9.61539
388 1KK8 BEF ADP 0.0000751 0.45143 9.74026
389 1OFH ADP 0.0001245 0.496 9.77011
390 5JCP GDP ALF 0.00000002113 0.59272 9.7852
391 4DID GDP 0.000000007398 0.66499 9.84456
392 5EE5 GTP 0.00000000007469 0.62823 9.85915
393 3KTA AP5 0.0001274 0.45271 9.89011
394 2WMO GTP 0.000000008246 0.6416 10
395 1NJF ADP 0.00002426 0.53795 10
396 1NJF AGS 0.00003324 0.53623 10
397 4BAS GNP 0.000000001002 0.75638 10.0503
398 1SQ5 ADP 0.00001233 0.52107 10.0649
399 5CK5 GDP 0.000000001396 0.73374 10.1266
400 4E03 ADP 0.00002282 0.51151 10.1942
401 1NF3 GNP 0.0000000452 0.50893 10.2564
402 5HPY GDP 0.00000001179 0.60141 10.3448
403 3GJ3 GDP 0.00000000005903 0.78485 10.4072
404 3GJ0 GDP 0.00000000007218 0.78078 10.4072
405 3GJ4 GDP 0.0000000001195 0.77057 10.4072
406 3GJ8 GDP 0.00000000006168 0.75572 10.4072
407 3GJ5 GDP 0.00000000007503 0.75198 10.4072
408 2CJW GDP 0.00000000001987 0.80688 10.4167
409 2ZJ5 ADP 0.01598 0.40314 10.4326
410 4ITR GDP 0.00000002204 0.68449 10.4712
411 2NGR GDP 0.000000006908 0.66604 10.4712
412 1A4R GNH 0.000000006198 0.61338 10.4712
413 1A4R GDP 0.000000005798 0.59825 10.4712
414 1GRN GDP 0.00000001514 0.59746 10.4712
415 2UZI GTP 0.0000000003377 0.78946 10.5769
416 5BXQ GDP 0.00000000005342 0.75823 10.6481
417 1IBR GNP 0.000000002153 0.53621 10.6481
418 2A9K GDP 0.0000000003061 0.76994 10.6952
419 5N69 ADP 0.0001003 0.45795 11.0553
420 4H1V GNP 0.0000007302 0.53985 11.1111
421 4RZ3 ADP 0.00004505 0.46756 11.1864
422 5GJC ATP 0.0001302 0.48919 11.1959
423 3GJ7 GDP 0.00000000009962 0.77426 11.2245
424 5H56 TYD 0.00009881 0.52668 11.2821
425 5H56 ADP 0.00009881 0.52668 11.2821
426 5DI3 GNP 0.00000000001586 0.6501 11.3514
427 5J1S ATP 0.0002261 0.40251 11.3821
428 1ZC3 GNP 0.0000000007364 0.77577 11.4286
429 1UAD GNP 0.0000000007589 0.55602 11.4286
430 2QZ4 ADP 0.00004944 0.48355 11.4504
431 3T12 GDP ALF 0.0000000005335 0.60362 11.7647
432 1M7G AV2 0.000001426 0.5669 11.8483
433 1M7G ADX 0.00001698 0.5669 11.8483
434 1M7G ADP 0.00003555 0.54717 11.8483
435 1U8Z GDP 0.0000000004069 0.58882 11.9048
436 3GJX GTP 0.00000000557 0.73216 12.037
437 2A5J GDP 0.00000000004684 0.73393 12.0419
438 3CNL GNP 0.0000000002544 0.76913 12.2137
439 2CE7 ADP 0.00004442 0.51717 12.2137
440 2WIC GNP 0.0000000009449 0.70422 12.3596
441 1CS4 GSP 0.000000001562 0.53501 12.7226
442 1AZT GSP 0.0000000007065 0.53144 12.7226
443 1G6H ADP 0.000002278 0.61229 12.8405
444 4HAT GNP 0.000000001559 0.52923 12.8571
445 1WA5 GTP 0.000000003275 0.49512 13.0682
446 1Z2A GDP 0.0000000006803 0.58522 13.0952
447 1Z0A GDP 0.00000000003727 0.73783 13.2184
448 1W7J ADP BEF 0.00008737 0.44896 13.245
449 1SVI GDP 0.0000000001377 0.78189 13.3333
450 4QRH 0O2 0.006495 0.42281 13.3333
451 2HT6 GDP 0.00000000000305 0.81997 13.486
452 4NCN GTP 0.0000000001102 0.6116 13.486
453 1WDT GTP 0.0000000896 0.5542 13.486
454 3T5G GDP 0.00000000005555 0.79629 13.8158
455 5TB5 GDP 0.00000000006292 0.72784 14
456 5TAR GDP 0.00000000008018 0.70035 14.1892
457 1XX6 ADP 0.0003827 0.46736 14.6597
458 5UFQ GNP 0.0000000002185 0.57052 14.7541
459 3RAB GNP 0.0000000001176 0.81209 14.7929
460 1G16 GDP 0.000000003053 0.57464 15.2941
461 4TMZ GSP 0.00000000009721 0.61275 15.3623
462 5UWT GNP 0.000000001561 0.75957 15.3846
463 5UWQ GNP 0.000000001033 0.54347 15.3846
464 5UWU GNP 0.000000001268 0.54147 15.3846
465 5UWJ GNP 0.000000001302 0.54121 15.3846
466 5UWW GNP 0.000000001367 0.54093 15.3846
467 5UWO GNP 0.000000001378 0.54068 15.3846
468 5UWR GNP 0.000000001373 0.54067 15.3846
469 5UWI GNP 0.000000001427 0.54024 15.3846
470 5UWH GNP 0.000000001554 0.53946 15.3846
471 5UWP GNP 0.000000001349 0.53026 15.3846
472 5UWS GNP 0.000000001549 0.52916 15.3846
473 5DI9 GNP 0.000000001941 0.52695 15.3846
474 1G7S GDP 0.0000000000004765 0.8474 15.5216
475 1DAR GDP 0.000000000007995 0.82532 15.5216
476 3EC1 GDP 0.00000000003727 0.79948 15.5216
477 4ZKD GDP 0.0000000001487 0.57073 15.5216
478 2ODE ALF GDP 0.000000001472 0.52267 15.6028
479 4YMU ATP 0.00006197 0.51134 15.8333
480 4B47 GDP 0.0000000000001644 0.92177 15.978
481 1F6B GDP 0.0000000001436 0.74093 16.1616
482 2WHX ADP 0.00001941 0.5508 16.285
483 2JLR ANP 0.0002183 0.44457 16.285
484 2OM2 GDP 0.000000001134 0.61051 16.6667
485 1UPT GTP 0.0000000005178 0.59893 16.6667
486 3A1S GDP 0.0000001247 0.61308 17.0543
487 3EWA ANP 0.00007919 0.49925 17.3913
488 1CXZ GSP 0.00000001963 0.69346 17.4419
489 3W5J GDP 0.00000003346 0.69114 17.5573
490 1KSH GDP 0.00000000001025 0.84926 18.2796
491 1NRJ GTP 0.00000001054 0.58096 18.3486
492 3WYG GTP 0.000000003051 0.52393 18.4211
493 3BC1 GNP 0.0000000003853 0.56649 18.4615
494 5WDR GNP 0.000000001301 0.54066 18.7134
495 4CVN ADP 0.00000803 0.56261 18.8482
496 4KVG GTP 0.0000000005735 0.7781 19.0476
497 1MKY GDP 0.0000000000007382 0.87354 19.084
498 1ZD9 GDP 0.0000000005859 0.63294 19.6809
499 4R98 GNH 0.000000004034 0.69934 19.9262
500 1GUA GNP 0.0000000009986 0.54194 21.5569
501 3NKV GNP 0.000000000506 0.56235 21.7143
502 1LFD GNP 0.0000000005508 0.55977 21.8391
503 1Z0J GTP 0.0000000003488 0.55454 22.0339
504 2W83 GTP 0.0000000001607 0.60488 22.0779
505 3DOE GTP 0.00000000001076 0.63884 23.4375
506 1X1R GDP 0.000000001014 0.54068 23.5955
507 4KAX GTP 0.00000000006041 0.81578 25.4658
508 2WJG GDP 0.00000000004877 0.78871 26.0638
509 3PQC GDP 0.000000008454 0.64245 26.1538
510 3CH5 GDP 0.00000000005471 0.75783 28.8462
511 2WJH GDP 0.000000000191 0.76615 29.5181
512 2WJH FLC 0.0000004166 0.61306 29.5181
513 5FG3 GDP 0.0000000000003607 0.86089 29.771
514 4HDQ GNP 0.000000003124 0.53224 30.7692
515 1FQJ GDP 0.000000001297 0.57967 30.9524
516 5DIF GNP 0.000000001323 0.5411 31.5789
517 4RD0 GDP 0.0000000000004526 0.69686 35.8779
518 2QN6 GDP 0.00000000000005962 0.94285 36.1323
519 2VOH CIT 0.02361 0.40368 42.3077
520 1KK1 GNP 0.0000000000001144 0.92932 42.4936
521 1Y3A GDP 0.0000000023 0.57363 50
Pocket No.: 2; Query (leader) PDB : 1D8T; Ligand: GDP; Similar sites found: 4
This union binding pocket(no: 2) in the query (biounit: 1d8t.bio1) has 16 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 2ZE7 AMP 0.004167 0.43909 3.55731
2 5LTJ BEF 0.0095 0.42528 4.58015
3 3WQT ANP 0.02099 0.40123 6.61578
4 4OHY ANP 0.0002005 0.40038 7.37913
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