Receptor
PDB id Resolution Class Description Source Keywords
1DQO 2.2 Å NON-ENZYME: SIGNAL_HORMONE CRYSTAL STRUCTURE OF THE CYSTEINE RICH DOMAIN OF MANNOSE RECEPTOR COMPLEXED WITH ACETYLGALACTOSAMINE-4-SULFATE MUS MUSCULUS BETA TREFOIL MULTILECTIN RECEPTOR PITUITARY HORMONES SULFATED CARBOHYDRATE SUGAR BINDING PROTEIN
Ref.: CRYSTAL STRUCTURE OF THE CYSTEINE-RICH DOMAIN OF MANNOSE RECEPTOR COMPLEXED WITH A SULFATED CARBOHYDRATE LIGAND. J.EXP.MED. V. 191 1105 2000
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ASG A:2001;
Valid;
none;
submit data
301.271 C8 H15 N O9 S CC(=O...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1FWV 2.2 Å NON-ENZYME: SIGNAL_HORMONE CRYSTAL STRUCTURE OF THE CYSTEINE-RICH DOMAIN OF MANNOSE RECEPTOR COMPLEXED WITH 3-SO4-LEWIS(A) MUS MUSCULUS BETA TREFOIL MANNOSE RECEPTOR SULFATED CARBOHYDRATE SUGAR BINDING PROTEIN
Ref.: THE MOLECULAR MECHANISM OF SULFATED CARBOHYDRATE RECOGNITION BY THE CYSTEINE-RICH DOMAIN OF MANNOSE RECEPTOR. J.MOL.BIOL. V. 305 481 2001
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 286 families.
1 1FWV Kd = 0.19 mM SGA MAG FUC n/a n/a
2 1DQO - ASG C8 H15 N O9 S CC(=O)N[C@....
3 1FWU Kd = 0.2 mM SGA MAG FUC n/a n/a
70% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 209 families.
1 1FWV Kd = 0.19 mM SGA MAG FUC n/a n/a
2 1DQO - ASG C8 H15 N O9 S CC(=O)N[C@....
3 1FWU Kd = 0.2 mM SGA MAG FUC n/a n/a
50% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 174 families.
1 1FWV Kd = 0.19 mM SGA MAG FUC n/a n/a
2 1DQO - ASG C8 H15 N O9 S CC(=O)N[C@....
3 1FWU Kd = 0.2 mM SGA MAG FUC n/a n/a
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ASG; Similar ligands found: 55
No: Ligand ECFP6 Tc MDL keys Tc
1 ASG 1 1
2 NAG FUC 0.539683 0.672131
3 HSQ 0.538462 0.661017
4 NDG 0.538462 0.661017
5 BM3 0.538462 0.661017
6 A2G 0.538462 0.661017
7 NGA 0.538462 0.661017
8 NAG 0.538462 0.661017
9 NDG GAL 0.532258 0.66129
10 NLC 0.532258 0.66129
11 GAL NDG 0.532258 0.66129
12 NDG NAG 0.507692 0.65625
13 CBS CBS 0.507692 0.65625
14 CBS 0.507692 0.65625
15 NAG GDL 0.507692 0.65625
16 L42 0.486842 0.904762
17 G6S NAG 0.486111 0.904762
18 NGS 0.483333 0.966102
19 NAG NAG NAG NDG 0.478261 0.646154
20 NAG NAG NAG NAG NAG NAG NAG NAG 0.478261 0.646154
21 NAG NAG NDG 0.478261 0.646154
22 CTO 0.478261 0.646154
23 NAG NAG NAG NAG NAG NAG 0.478261 0.646154
24 NDG NAG NAG NAG 0.478261 0.646154
25 NAG NAG NAG NAG NAG 0.478261 0.646154
26 NAG NAG NAG NAG NDG 0.478261 0.646154
27 NDG NAG NAG 0.478261 0.646154
28 NDG NAG NAG NDG 0.478261 0.646154
29 NAG NAG NDG NAG 0.478261 0.646154
30 HS2 0.472222 0.666667
31 FUC GAL NDG 0.465753 0.650794
32 FUC GAL NAG 0.465753 0.650794
33 NDG GAL FUC 0.465753 0.650794
34 FUL GAL NAG 0.465753 0.650794
35 DR2 0.465753 0.650794
36 GAL NAG FUC 0.465753 0.650794
37 NAG GAL FUC 0.465753 0.650794
38 MAN BMA NAG 0.464789 0.66129
39 GLA GAL NAG 0.464789 0.66129
40 UNU GAL NAG 0.461538 0.646154
41 GCS GCS NAG 0.443038 0.621212
42 NAG GAL NAG 0.434211 0.65625
43 ASG GCD 0.43038 0.875
44 BUL 0.430233 0.783784
45 TCG 0.428571 0.611111
46 BLG 0.425287 0.763158
47 16G 0.419355 0.774194
48 BMX 0.419355 0.774194
49 4QY 0.419355 0.774194
50 GAL NAG GAL NAG GAL NAG 0.417722 0.646154
51 NAG GAL GAL NAG 0.417722 0.65625
52 AMU 0.415385 0.683333
53 GAL BGC NAG GAL 0.410256 0.66129
54 GCD ASG 0.402439 0.875
55 NGK GCD 0.402439 0.875
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1FWV; Ligand: SGA MAG FUC; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 1fwv.bio1) has 11 residues
No: Leader PDB Ligand Sequence Similarity
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