Receptor
PDB id Resolution Class Description Source Keywords
1E0S 2.28 Å NON-ENZYME: OTHER SMALL G PROTEIN ARF6-GDP HOMO SAPIENS G PROTEIN RAS ARF ARF6 MEMBRANE TRAFFIC
Ref.: STRUCTURE OF ARF6-GDP SUGGESTS A BASIS FOR GUANINE NUCLEOTIDE EXCHANGE FACTORS SPECIFICITY NAT.STRUCT.BIOL. V. 7 466 2000
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
BME A:201;
Invalid;
none;
submit data
78.133 C2 H6 O S C(CS)...
GDP A:200;
Valid;
none;
submit data
443.201 C10 H15 N5 O11 P2 c1nc2...
NH4 A:202;
Invalid;
none;
submit data
18.038 H4 N [NH4+...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3N5C 1.82 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF ARF6DELTA13 COMPLEXED WITH GDP HOMO SAPIENS SMALL G PROTEIN ; SMALL GTP-BINDING PROTEIN ARF ADP-RIBOSYFACTOR 6 TRAFFIC ENDOCYTOSIS UNFOLDED PROTEIN PROTEIN T
Ref.: SAXS AND X-RAY CRYSTALLOGRAPHY SUGGEST AN UNFOLDING FOR THE GDP/GTP CONFORMATIONAL SWITCH OF THE SMALL ARF6. J.MOL.BIOL. V. 402 696 2010
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1256 families.
1 3N5C - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 1E0S - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1068 families.
1 1E0S - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
50% Homology Family (19)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 181 families.
1 4V0K - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 4V0L - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
3 2X77 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
4 1RRG - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
5 1HUR - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
6 1O3Y - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
7 1FZQ Kd = 24 nM GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
8 1Z6Y - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
9 1ZJ6 - G3D C10 H16 N5 O14 P3 c1nc2c(n1[....
10 1YZG - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
11 3N5C - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
12 1E0S - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
13 1ZD9 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
14 2AL7 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
15 3AQ4 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
16 4Y0V - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
17 4YLG - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
18 1MR3 - G3D C10 H16 N5 O14 P3 c1nc2c(n1[....
19 4BAS - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GDP; Similar ligands found: 153
No: Ligand ECFP6 Tc MDL keys Tc
1 GDP 1 1
2 GTP 0.909091 1
3 GP3 0.881579 0.973684
4 GNH 0.858974 0.986667
5 GNP 0.839506 0.973684
6 G 0.828947 0.986486
7 5GP 0.828947 0.986486
8 G1R 0.82716 0.986667
9 GCP 0.82716 0.973684
10 GSP 0.817073 0.948718
11 GAV 0.797619 0.961039
12 GMV 0.792683 0.973684
13 G2P 0.77381 0.961039
14 G2R 0.770115 0.961039
15 GDP MG 0.759036 0.923077
16 GP2 0.756098 0.961039
17 GDP BEF 0.75 0.9
18 GDD 0.747253 0.961039
19 GKE 0.747253 0.961039
20 GDC 0.747253 0.961039
21 GPG 0.741573 0.961039
22 G3D 0.732558 0.986486
23 ALF 5GP 0.729412 0.888889
24 Y9Z 0.728261 0.902439
25 GTP MG 0.724138 0.923077
26 BEF GDP 0.724138 0.888889
27 G5P 0.723404 0.973684
28 GFB 0.72043 0.961039
29 GTG 0.72043 0.936709
30 GDR 0.72043 0.961039
31 G4P 0.715909 0.986486
32 GCP G 0.715909 0.935065
33 6CK 0.712766 0.936709
34 G3A 0.712766 0.973684
35 GDP ALF 0.7 0.888889
36 GDP AF3 0.7 0.888889
37 YGP 0.698925 0.901235
38 JB2 0.697917 0.961039
39 GKD 0.697917 0.961039
40 GDX 0.690722 0.973684
41 GPD 0.690722 0.925
42 GMP 0.684211 0.88
43 0O2 0.666667 0.986486
44 G G 0.659574 0.935065
45 JB3 0.656863 0.948718
46 NGD 0.650485 0.961039
47 GDP 7MG 0.636364 0.911392
48 DGI 0.636364 0.923077
49 U2G 0.634615 0.936709
50 GPX 0.634409 0.946667
51 IDP 0.632184 0.972973
52 2MD 0.632075 0.891566
53 CAG 0.62963 0.880952
54 CG2 0.622642 0.936709
55 FEG 0.619048 0.879518
56 MGD 0.614679 0.891566
57 ZGP 0.613208 0.869048
58 GH3 0.612903 0.973333
59 3GP 0.611765 0.946667
60 MD1 0.607143 0.891566
61 PGD 0.59292 0.925
62 DGT 0.591398 0.923077
63 BGO 0.588785 0.924051
64 TPG 0.582609 0.840909
65 DBG 0.582609 0.948718
66 2GP 0.574713 0.96
67 FE9 0.570175 0.776596
68 I2C FE2 CMO CMO 0.566372 0.808989
69 G A A A 0.553571 0.923077
70 MGP 0.553191 0.961039
71 U A G G 0.548673 0.935065
72 G4M 0.548387 0.880952
73 6G0 0.547368 0.961039
74 G1R G1R 0.542373 0.924051
75 P2G 0.527473 0.883117
76 PGD O 0.525 0.850575
77 ADP 0.522222 0.92
78 GGM 0.517544 0.901235
79 DG 0.516484 0.910256
80 DGP 0.516484 0.910256
81 P1G 0.516129 0.871795
82 G G U 0.509259 0.935065
83 G1G 0.508475 0.925
84 IMP 0.505495 0.959459
85 G C 0.504348 0.9
86 GPC 0.491525 0.879518
87 G7M 0.483871 0.948052
88 6AD 0.479592 0.841463
89 ATP 0.473684 0.92
90 G2Q 0.471154 0.961039
91 U G A 0.469697 0.888889
92 5FA 0.46875 0.92
93 AQP 0.46875 0.92
94 GTA 0.468468 0.936709
95 7DD 0.468085 0.906667
96 G G G RPC 0.466102 0.875
97 SGP 0.463158 0.82716
98 01G 0.462963 0.902439
99 B4P 0.457447 0.894737
100 AP5 0.457447 0.894737
101 A2D 0.456522 0.894737
102 G G G C 0.455285 0.9125
103 ACQ 0.454545 0.896104
104 5GP 5GP 0.454545 0.883117
105 ANP 0.454545 0.896104
106 A G C C 0.451613 0.911392
107 APC G U 0.45082 0.886076
108 G U34 0.449153 0.888889
109 DG DG 0.448598 0.865854
110 ITT 0.447917 0.868421
111 BA3 0.446809 0.894737
112 35G 0.444444 0.933333
113 C2E 0.444444 0.921053
114 PCG 0.444444 0.933333
115 MGO 0.441176 0.864198
116 AN2 0.4375 0.907895
117 G C C C 0.4375 0.924051
118 M33 0.43299 0.883117
119 UCG 0.429688 0.911392
120 A G U 0.42963 0.888889
121 ACP 0.428571 0.896104
122 MGQ 0.424528 0.935897
123 7DT 0.424242 0.906667
124 APR 0.424242 0.894737
125 AR6 0.424242 0.894737
126 93A 0.42268 0.833333
127 A4P 0.420168 0.869048
128 SAP 0.42 0.873418
129 AD9 0.42 0.896104
130 AGS 0.42 0.873418
131 G8D 0.42 0.875
132 CA0 0.418367 0.896104
133 ATF 0.417476 0.884615
134 AGO 0.414634 0.888889
135 NIA 0.413043 0.82716
136 MGV 0.412844 0.890244
137 TAT 0.411765 0.884615
138 A1R 0.411215 0.839506
139 ADQ 0.411215 0.871795
140 RGT 0.410714 0.909091
141 CGP 0.409836 0.86747
142 AMP 0.408602 0.893333
143 A 0.408602 0.893333
144 UP5 0.40678 0.873418
145 C2R 0.406593 0.906667
146 AMZ 0.406593 0.918919
147 JBT 0.405882 0.778947
148 A22 0.40566 0.907895
149 25L 0.405405 0.907895
150 ADX 0.40404 0.809524
151 8OD 0.401961 0.946667
152 4TC 0.4 0.851852
153 50T 0.4 0.883117
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3N5C; Ligand: GDP; Similar sites found: 506
This union binding pocket(no: 1) in the query (biounit: 3n5c.bio2) has 16 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1CLU DBG 0.0000000125 0.74532 None
2 2GJ8 ALF GDP 0.000000000134 0.57122 None
3 1XX6 ADP 0.0003825 0.46737 None
4 2F3R G5P 0.004857 0.44431 None
5 1CMC SAM 0.01831 0.40997 None
6 5HGZ ACO 0.02002 0.40524 None
7 1D2E GDP 0.0000000002054 0.77396 1.23457
8 1UJ2 ADP 0.000004724 0.58685 1.85185
9 1UJ2 C5P 0.000005984 0.58176 1.85185
10 1XEX ATP 0.00006978 0.52688 1.85185
11 3DC4 ADP 0.000007756 0.52031 1.85185
12 3KTA AP5 0.00004817 0.51834 1.85185
13 1KO8 6PG 0.00008914 0.51073 1.85185
14 2W58 ADP 0.00000146 0.49825 1.85185
15 2ZPT A3P 0.009885 0.44768 1.85185
16 2D2F ADP 0.00001696 0.44653 1.85185
17 1Q20 PLO 0.005577 0.44251 1.85185
18 1NVV GNP 0.000000006111 0.73017 2.46914
19 1FP6 ADP 0.000022 0.53455 2.46914
20 4QRH 0O2 0.003871 0.43373 2.46914
21 4ITM ATP 0.01366 0.41351 2.46914
22 4PJ3 ANP 0.00226 0.40905 2.46914
23 2C5L GTP 0.000000002689 0.74785 2.5641
24 2C78 GNP 0.00000000004037 0.8243 3.08642
25 2C77 GNP 0.00000000006049 0.81191 3.08642
26 1KK1 GNP 0.00000000001118 0.79591 3.08642
27 1TQ4 GDP 0.000000002636 0.7325 3.08642
28 3ZS9 ADP ALF 0.000004062 0.5901 3.08642
29 3A4M ADP 0.0000004033 0.57446 3.08642
30 2IXE ATP 0.0000332 0.53626 3.08642
31 3P4X ADP 0.000008973 0.53137 3.08642
32 2DPY ADP 0.0001438 0.50096 3.08642
33 5LB3 ADP 0.0001389 0.49456 3.08642
34 2WOJ ADP ALF 0.000004068 0.44257 3.08642
35 5MEX SZZ 0.01125 0.43143 3.08642
36 4KBF AMP 0.002132 0.42645 3.08642
37 5EP2 AZU 0.005737 0.42543 3.08642
38 5MEX PAP 0.006258 0.42171 3.08642
39 4M7V NAP 0.02058 0.4124 3.08642
40 2R5N RP5 0.02752 0.40922 3.08642
41 2R5N TPP 0.02649 0.40902 3.08642
42 2R5N R5P 0.03038 0.40595 3.08642
43 2B4D COA 0.01735 0.40202 3.08642
44 4NSQ COA 0.01478 0.40178 3.68421
45 3ZQ6 ADP ALF 0.000004231 0.58923 3.7037
46 1IWE IMP 0.00009711 0.58229 3.7037
47 5L3W GDP 0.000002506 0.57621 3.7037
48 1NJF AGS 0.00002709 0.54056 3.7037
49 1SVM ATP 0.0001689 0.5361 3.7037
50 1NJF ADP 0.00002659 0.53604 3.7037
51 2C9O ADP 0.00004981 0.52535 3.7037
52 4QM7 GTP 0.00002224 0.52496 3.7037
53 3BOS CDP 0.00002263 0.52461 3.7037
54 2BEK ATP 0.0002352 0.51795 3.7037
55 4BFW ZVW 0.0003068 0.51454 3.7037
56 1JJV ATP 0.00001134 0.50398 3.7037
57 4PX9 ADP 0.0002131 0.47005 3.7037
58 2B8T THM 0.002094 0.44859 3.7037
59 1AQU A3P 0.003596 0.4313 3.7037
60 4AF0 IMP 0.01305 0.41142 3.7037
61 3BER AMP 0.006586 0.4097 3.7037
62 2VBQ BSJ 0.02501 0.41137 4.24242
63 4RD0 GDP 0.0000000000222 0.83695 4.32099
64 2QN6 GDP 0.000000000008778 0.80043 4.32099
65 2RCN GDP 0.00000000009373 0.77549 4.32099
66 4K81 GTP 0.000000007748 0.72776 4.32099
67 4WZ6 ATP 0.000003562 0.58846 4.32099
68 3BFV ADP 0.000001318 0.58216 4.32099
69 5I34 GDP 0.000004797 0.55954 4.32099
70 2ZFI ADP 0.000005914 0.55177 4.32099
71 3ZFD ANP 0.00001427 0.54049 4.32099
72 2RGX AP5 0.0002263 0.5238 4.32099
73 1E2K TMC 0.0002455 0.51954 4.32099
74 2XT3 ADP 0.000001371 0.51891 4.32099
75 2NCD ADP 0.000003821 0.51872 4.32099
76 4TTQ ATP 0.00003204 0.51757 4.32099
77 4AG5 ADP 0.000005345 0.51316 4.32099
78 4GOX A3P 0.0001307 0.5094 4.32099
79 1D2N ANP 0.0001162 0.50753 4.32099
80 3QVV A3P 0.0005819 0.49513 4.32099
81 2IS6 ADP 0.000122 0.4905 4.32099
82 1NY5 ADP 0.0002416 0.48749 4.32099
83 1VHT BA3 0.0002327 0.48315 4.32099
84 4LJ9 ACP 0.0001839 0.48219 4.32099
85 1W5T ANP 0.0004866 0.47739 4.32099
86 3DKP ADP 0.0003059 0.47189 4.32099
87 1W5T ADP 0.0009984 0.45798 4.32099
88 3QVV 3QV 0.007254 0.44538 4.32099
89 5E5U MLI 0.006969 0.43791 4.32099
90 4HUT ATP 0.008418 0.42963 4.32099
91 2V2V V12 0.0363 0.40953 4.32099
92 4BR5 ANP 0.02966 0.40648 4.32099
93 2BVN GNP 0.00000000002204 0.82009 4.83461
94 1D8T GDP 0.00000000001821 0.80866 4.83461
95 1SKQ GDP 0.000000000004264 0.81403 4.93827
96 3EC1 GDP 0.000000000489 0.74698 4.93827
97 2HF9 GSP 0.000000008971 0.69968 4.93827
98 1JWY GDP 0.0000000175 0.68207 4.93827
99 1SVI GDP 0.000000007905 0.67099 4.93827
100 4LPS GDP 0.00000002513 0.66664 4.93827
101 5KUT GDP 0.00000003633 0.65913 4.93827
102 3E70 GDP 0.0000003508 0.61288 4.93827
103 1XP8 AGS 0.000002736 0.55426 4.93827
104 5GJC ATP 0.000007245 0.54766 4.93827
105 1V8K ANP 0.00001248 0.53666 4.93827
106 1YTM ATP 0.00003483 0.53287 4.93827
107 1IN4 ADP 0.00003612 0.52963 4.93827
108 2Q2Y ADP 0.0001738 0.5273 4.93827
109 2Q2Y MKR 0.0001814 0.52506 4.93827
110 1JWY ADP 0.00002786 0.52367 4.93827
111 1RRC ADP 0.000001145 0.51904 4.93827
112 4HSE ADP 0.00004129 0.51564 4.93827
113 1XKV ATP 0.00005483 0.51284 4.93827
114 1OS1 ATP 0.0001731 0.51277 4.93827
115 1OS1 PYR 0.0001918 0.51221 4.93827
116 3B5J 12D 0.00001237 0.51082 4.93827
117 2ZPA ADP 0.0000968 0.509 4.93827
118 3QKT ANP 0.0001876 0.50373 4.93827
119 5BQ5 ADP BEF 0.00003986 0.49016 4.93827
120 2Z5F A3P 0.0006123 0.47256 4.93827
121 1J99 AND 0.007945 0.43468 4.93827
122 2D7D ADP 0.00238 0.43034 4.93827
123 3F8K COA 0.0223 0.40144 5
124 2UZI GTP 0.000000003135 0.74166 5.26316
125 3IIJ ADP 0.000003648 0.56155 5.55556
126 1BG2 ADP 0.0000001776 0.53018 5.55556
127 2Y65 ADP 0.0000008147 0.52748 5.55556
128 2FAH GDP 0.00003367 0.52575 5.55556
129 3H4S ADP 0.0000009632 0.52334 5.55556
130 4FRZ ADP 0.000004375 0.51632 5.55556
131 4FCW ADP 0.00005265 0.51069 5.55556
132 4IOK ADP 0.0002418 0.50381 5.55556
133 4IOK XPO 0.0001869 0.50381 5.55556
134 3BFX A3P 0.0003774 0.48053 5.55556
135 4GBM A3P 0.000572 0.47802 5.55556
136 2ZE7 AMP 0.001756 0.45766 5.55556
137 2ZE7 DST 0.001895 0.45766 5.55556
138 1OYY AGS 0.000652 0.45657 5.55556
139 1X8J A3P 0.005625 0.45014 5.55556
140 2GWH A3P 0.002154 0.44197 5.55556
141 2FSH ANP 0.001823 0.42882 5.55556
142 1CJW COT 0.01939 0.41003 5.55556
143 1S7N COA 0.01501 0.4051 5.55556
144 1KUV CA5 0.03031 0.40379 5.55556
145 1QHH ATP 0.01054 0.4025 5.55556
146 4GDX GLU 0.02043 0.40011 5.55556
147 2HCJ GDP 0.000000000008372 0.80141 5.67164
148 1F2U ATP 0.0003431 0.4945 6.04027
149 1WQ1 GDP 0.000000006182 0.72109 6.17284
150 4LC1 GDP 0.00000000214 0.71217 6.17284
151 4NE2 SH2 0.00003328 0.56016 6.17284
152 4NE2 ADP 0.00002899 0.56016 6.17284
153 4P32 ADP 0.00002167 0.54528 6.17284
154 4ZG4 VO4 ADP 0.00002447 0.54502 6.17284
155 1OXV ANP 0.000004381 0.54387 6.17284
156 4ZNL BEF ADP 0.00001826 0.53228 6.17284
157 2QG6 NMN 0.00006755 0.53141 6.17284
158 2YOH WMJ 0.0001035 0.53049 6.17284
159 3QXC ATP 0.00006639 0.5299 6.17284
160 3KJI ADP 0.00002831 0.52933 6.17284
161 2QQ0 ANP 0.0001317 0.52364 6.17284
162 2QQ0 THM 0.0001136 0.52364 6.17284
163 2QQ0 TMP 0.0001377 0.52266 6.17284
164 1Z6T ADP 0.00004636 0.52184 6.17284
165 1UKZ ADP 0.0001614 0.52069 6.17284
166 1FNN ADP 0.0000829 0.51225 6.17284
167 1QF9 C5P 0.0004562 0.50186 6.17284
168 3DZD ADP 0.0001428 0.49588 6.17284
169 2XAU ADP 0.0002182 0.48448 6.17284
170 3B9Q MLI 0.000002007 0.45899 6.17284
171 3MGB PAP 0.003392 0.43651 6.17284
172 3RC3 ANP 0.003069 0.41821 6.17284
173 4WOP CTP 0.0004288 0.41304 6.17284
174 2WIC GNP 0.00000000009594 0.78019 6.79012
175 1YRB GDP 0.0000000004063 0.75985 6.79012
176 3WXM GTP 0.000000001506 0.75738 6.79012
177 2QEN ADP 0.000001355 0.59532 6.79012
178 1QF5 GDP 0.00002857 0.57906 6.79012
179 1XMV ADP 0.000003653 0.5651 6.79012
180 1P9B GDP 0.000006503 0.56269 6.79012
181 2ZR9 DTP 0.000003455 0.56265 6.79012
182 2VB6 ADP BEF 0.00001837 0.55112 6.79012
183 3FB4 AP5 0.00009666 0.54049 6.79012
184 1S3G AP5 0.00009684 0.54044 6.79012
185 1JI0 ATP 0.000002344 0.53971 6.79012
186 4PFO ADP 0.00003906 0.53933 6.79012
187 4MKG AP5 0.0001163 0.53634 6.79012
188 4MKF AP5 0.0001298 0.53513 6.79012
189 2VVG ADP 0.0000001765 0.53138 6.79012
190 1AKY AP5 0.0001391 0.52968 6.79012
191 1DAK DPU 0.0004143 0.51014 6.79012
192 1G41 ADP 0.00006455 0.50949 6.79012
193 1P72 ADP 0.000252 0.50937 6.79012
194 4TMK T5A 0.0006286 0.49071 6.79012
195 1QF5 RPL 0.006459 0.4823 6.79012
196 4IHQ ADP 0.0001105 0.48219 6.79012
197 1G3M PCQ 0.005532 0.44843 6.79012
198 4JD3 PLM 0.04654 0.40543 6.79012
199 4JD3 COA 0.04336 0.40543 6.79012
200 1BOB ACO 0.02187 0.40186 6.79012
201 4NON GDP 0.000000003734 0.74355 7.40741
202 5HCN GCP 0.0000000079 0.66654 7.40741
203 3UIE ANP 0.000004175 0.56573 7.40741
204 5H56 TYD 0.00001881 0.56286 7.40741
205 5H56 ADP 0.00001881 0.56286 7.40741
206 3NHB ADP 0.000002112 0.52678 7.40741
207 1F5N GNP 0.00007819 0.52637 7.40741
208 3COB ADP 0.000001076 0.52395 7.40741
209 2C04 GCP 0.000001733 0.52261 7.40741
210 2B8W ALF 5GP 0.0001452 0.5092 7.40741
211 5L3R GCP 0.0000002082 0.50062 7.40741
212 5MZN ADP 0.002466 0.44023 7.40741
213 2OG2 MLI 0.000002873 0.43215 7.40741
214 1QSN COA 0.01485 0.40355 7.40741
215 4B47 GDP 0.000000000002866 0.821 8.02469
216 4R98 GNH 0.000000003306 0.70337 8.02469
217 5L3S GNP 0.0000003406 0.63853 8.02469
218 5L3V GDP 0.0000001357 0.59206 8.02469
219 5I0H ADP BEF 0.00001743 0.54744 8.02469
220 1SQ5 ADP 0.000008732 0.54733 8.02469
221 4NU0 AP5 0.00007796 0.54262 8.02469
222 5X40 ACP 0.00003734 0.53603 8.02469
223 2JLR ANP 0.00002112 0.53539 8.02469
224 4KFU ACP 0.000001884 0.53335 8.02469
225 1JJ7 ADP 0.0000001544 0.53015 8.02469
226 2CHG ANP 0.00004666 0.5217 8.02469
227 2VF7 ADP 0.00007325 0.50395 8.02469
228 2WHX ADP 0.000009036 0.50221 8.02469
229 1R6B ADP 0.00008913 0.49995 8.02469
230 4QOS ADP 0.0001359 0.4942 8.02469
231 4R2I ANP 0.0009184 0.46135 8.02469
232 3IUY AMP 0.005969 0.4117 8.02469
233 4AVB ACO 0.01879 0.40661 8.02469
234 4CVN ADP 0.000005004 0.52919 8.0292
235 5FG3 GDP 0.0000000000166 0.78798 8.64198
236 1DAR GDP 0.00000000007295 0.78056 8.64198
237 3KUD GDP 0.000000003313 0.72769 8.64198
238 4HI0 GDP 0.000000005842 0.71576 8.64198
239 4BQS K2Q 0.00003268 0.55906 8.64198
240 4BQS ADP 0.00003268 0.55906 8.64198
241 3TMK T5A 0.00005673 0.53701 8.64198
242 3QF7 ANP 0.00004066 0.52715 8.64198
243 1G6H ADP 0.0000002906 0.52143 8.64198
244 4YS0 ADP 0.001246 0.40979 8.64198
245 2IVF MD1 0.03089 0.40662 8.64198
246 1LFD GNP 0.000000004256 0.7351 9.1954
247 1WF3 GNP 0.000000001273 0.76398 9.25926
248 3DDC GNP 0.000000009261 0.72121 9.25926
249 3PQC GDP 0.0000002054 0.62758 9.25926
250 1M7G ADX 0.000002008 0.61365 9.25926
251 3W5J GDP 0.000000007326 0.60851 9.25926
252 1M7G AV2 0.0000003304 0.59502 9.25926
253 1M7G ADP 0.000003935 0.59499 9.25926
254 3DEF GDP 0.000003129 0.57486 9.25926
255 3TBK ANP 0.001812 0.42385 9.25926
256 1G7S GDP 0.00000000001187 0.82282 9.87654
257 4XTR ATP 0.000002339 0.59492 9.87654
258 4XTR ADP 0.000005066 0.57073 9.87654
259 1CR1 TTP 0.00001817 0.54656 9.87654
260 1ZIN AP5 0.00008049 0.5446 9.87654
261 1W7J ADP BEF 0.00004131 0.52423 9.87654
262 1F9V ADP 0.000004869 0.51502 9.87654
263 2AWN ADP 0.0000001872 0.50686 9.87654
264 1Z83 AP5 0.0003747 0.50212 9.87654
265 4IEE AGS 0.0001944 0.4739 9.87654
266 4XVU ATP 0.000003213 0.46954 9.87654
267 3B7G ANP 0.0004725 0.46593 9.87654
268 1T8U UAP SGN IDS SGN 0.003398 0.46047 9.87654
269 1T8U A3P 0.001667 0.45147 9.87654
270 4IDN GNP 0.0001048 0.42327 9.87654
271 4NCN GTP 0.000000001326 0.75381 10.4938
272 1W0J ADP 0.000001629 0.58835 10.4938
273 4U00 ADP 0.0000006473 0.50982 10.4938
274 1W0J ADP BEF 0.0001505 0.49977 10.4938
275 5WRJ A3P 0.001087 0.46619 10.4938
276 5WRI A3P 0.001313 0.45846 10.4938
277 4A4Z ANP 0.001611 0.43825 10.4938
278 3BD9 A3P 0.004615 0.41941 10.4938
279 2PZ8 APC 0.01267 0.4104 10.4938
280 2O0J ADP 0.004816 0.40389 10.4938
281 1B0U ATP 0.00009003 0.50542 10.687
282 5M04 GDP 0.000000000001791 0.83055 11.1111
283 5KSZ GCP 0.000001262 0.55361 11.1111
284 3FYH ADP 0.00002534 0.54649 11.1111
285 5TSH ANP 0.00001076 0.53966 11.1111
286 2GDJ ANP 0.00001696 0.53044 11.1111
287 1T5C ADP 0.0000003194 0.5217 11.1111
288 5TSH ADP 0.00002529 0.48784 11.1111
289 2JAQ DCP 0.002122 0.45013 11.1111
290 1VKJ A3P 0.003859 0.43379 11.1111
291 3MD0 GDP 0.00000000002989 0.77581 11.7284
292 3TK1 GDP 0.00000000008486 0.73707 11.7284
293 4P4T GDP 0.00000002353 0.68312 11.7284
294 1NN5 ANP 0.00001199 0.57452 11.7284
295 1IHU ADP 0.000006365 0.57364 11.7284
296 1IHU AF3 0.000005668 0.57364 11.7284
297 1G3Q ADP 0.000005398 0.55714 11.7284
298 1ION ADP 0.00001204 0.54398 11.7284
299 1G6O ADP 0.00006437 0.50955 11.7284
300 1U0J ADP 0.0003125 0.46256 11.7284
301 1NN5 2DT 0.0373 0.42288 11.7284
302 4IXH IMP 0.01736 0.40684 11.7284
303 1MKY GDP 0.00000000001581 0.81151 12.3457
304 4R43 GDP 0.00003308 0.51692 12.3457
305 5N69 ADP 0.00002621 0.48035 12.3457
306 1X1R GDP 0.000000006174 0.72995 12.963
307 1G7C 5GP 0.00000001419 0.67388 12.963
308 4D81 ADP 0.00001903 0.53754 12.963
309 3FVQ ATP 0.00008537 0.51401 12.963
310 4OI4 ATP 0.0001517 0.50624 12.963
311 1OFH ADP 0.00009227 0.50216 12.963
312 1NST A3P 0.0021 0.4425 12.963
313 2PEZ DAT 0.00000198 0.61587 13.5802
314 1LVG ADP 0.00000009966 0.59942 13.5802
315 3FWY ADP 0.000004292 0.57133 13.5802
316 3VX3 ADP 0.00005817 0.51966 13.5802
317 1W4R TTP 0.0005247 0.48704 13.5802
318 2ORV 4TA 0.002985 0.44626 13.5802
319 2PEZ GGZ 0.00000198 0.41363 13.5802
320 1X6V ADP 0.000001703 0.61319 14.1975
321 2OFW ADX 0.000004177 0.60955 14.1975
322 4WZA ACP 0.00009306 0.56066 14.1975
323 4WZA ADP 0.00009306 0.56066 14.1975
324 2PL3 ADP 0.0002795 0.46554 14.1975
325 1OE0 TTP 0.002998 0.44776 14.1975
326 3H86 AP5 0.0003908 0.5026 14.5833
327 3ZIA ADP 0.000002904 0.57641 14.7541
328 3ZIA ATP 0.00000253 0.57259 14.7541
329 1H65 GDP 0.000006924 0.56941 14.8148
330 1L2T ATP 0.00007596 0.52304 14.8148
331 2V7Q ATP 0.000001894 0.58196 16
332 2CK3 ADP 0.0002221 0.49813 16
333 2CK3 ANP 0.0002291 0.49098 16
334 2V7Q ADP 0.0002422 0.47662 16
335 1PUJ GNP 0.00000000004514 0.80527 17.284
336 3Q85 GNP 0.00000000002355 0.80345 17.284
337 5TB5 GDP 0.0000000005452 0.74939 17.9012
338 5UQW GDP 0.000000002356 0.74475 17.9012
339 5TAR GDP 0.0000000007512 0.66603 17.9012
340 5O2T GSP 0.000000002977 0.53674 17.9012
341 1NVU GTP 0.000000004948 0.73471 18.5185
342 1RJ9 GCP 0.0000009495 0.64898 18.5185
343 2IYL GDP 0.0000006972 0.59505 18.5185
344 2W2X GSP 0.00000005674 0.66793 19.1358
345 4U5X GNP 0.00000006602 0.66153 19.1358
346 1G4U GDP 0.0000001286 0.64759 19.1358
347 1ZUI SKM 0.00009135 0.53624 19.1358
348 2BIF ANP 0.00008759 0.53417 19.1358
349 2BIF SIN 0.0001508 0.53417 19.1358
350 1YQT ADP 0.000008498 0.50462 19.1358
351 1MH1 GNP 0.00000005709 0.50168 19.1358
352 2J0V GDP 0.00000004643 0.65412 19.7531
353 3RLF ANP 0.00007059 0.5225 19.7531
354 2VHJ ADP 0.005839 0.42506 19.7531
355 3MJY FMN 0.02995 0.40518 19.7531
356 3MJY IJZ 0.02995 0.40518 19.7531
357 2KIN ADP 0.0000002774 0.52324 20
358 1DS6 GDP 0.00000002053 0.6664 20.9877
359 4YMU ATP 0.00002413 0.53094 20.9877
360 2CE7 ADP 0.00002464 0.52927 20.9877
361 2GK6 ADP 0.002876 0.41514 22.2222
362 1M7B GTP 0.00000006722 0.66436 22.8395
363 1GWN GTP 0.0000001107 0.65386 22.8395
364 5KSP GDP 0.0000002211 0.60072 22.8395
365 1CS4 GSP 0.00000000002233 0.85433 24.0741
366 1AZT GSP 0.00000000002729 0.8531 24.0741
367 2XTZ GSP 0.0000000000388 0.83589 24.0741
368 2ZEJ GDP 0.000000001028 0.76858 24.0741
369 3REF GDP 0.00000004114 0.67781 24.0741
370 3A1S GDP 0.0000005292 0.6045 24.4186
371 3CH5 GDP 0.0000000001496 0.77113 24.6914
372 5BXQ GDP 0.0000000001781 0.76758 24.6914
373 4HAT GNP 0.000000001367 0.7653 24.6914
374 5UWP GNP 0.000000001384 0.76503 24.6914
375 5UWI GNP 0.000000001511 0.76028 24.6914
376 3GJ3 GDP 0.0000000002041 0.75974 24.6914
377 3M1I GTP 0.000000001583 0.75928 24.6914
378 5UWR GNP 0.000000001656 0.7583 24.6914
379 5UWT GNP 0.000000001902 0.75532 24.6914
380 1IBR GNP 0.000000002141 0.75277 24.6914
381 3GJ0 GDP 0.0000000003638 0.74804 24.6914
382 4D0N GDP 0.00000001369 0.67461 24.6914
383 2GCN GDP 0.0000001339 0.65285 24.6914
384 1CXZ GSP 0.0000001345 0.65277 24.6914
385 5HPY GDP 0.0000000954 0.65051 24.6914
386 1OW3 GDP 0.0000001582 0.63999 24.6914
387 1TX4 ALF GDP 0.000000338 0.63603 24.6914
388 5IRC GDP 0.000000998 0.59512 24.6914
389 5DIF GNP 0.00000000135 0.54413 24.6914
390 5UWQ GNP 0.000000001434 0.54392 24.6914
391 5UWU GNP 0.000000001519 0.54316 24.6914
392 5UWW GNP 0.000000001667 0.54253 24.6914
393 5UWH GNP 0.000000001706 0.54197 24.6914
394 5DHF GNP 0.000000001735 0.54194 24.6914
395 5UWJ GNP 0.000000001765 0.54162 24.6914
396 5UWO GNP 0.000000001827 0.54146 24.6914
397 5UWS GNP 0.000000001961 0.53055 24.6914
398 5DI9 GNP 0.000000002135 0.52938 24.6914
399 3GJ8 GDP 0.000000000185 0.7668 25.3086
400 3GJ5 GDP 0.0000000002243 0.76288 25.3086
401 3GJ7 GDP 0.0000000004183 0.74521 25.3086
402 3GJ4 GDP 0.0000000005305 0.7404 25.3086
403 1K6M AGS 0.00005596 0.52744 25.9259
404 1NRJ GTP 0.000000001768 0.7409 26.6055
405 1B7T ADP 0.00008376 0.50414 26.9231
406 1KAO GDP 0.00000000116 0.74223 26.9461
407 1TAD GDP 0.00000000003074 0.85052 27.1605
408 3Q72 GNP 0.0000000002284 0.73848 27.1605
409 1TAD ALF 0.00000000003074 0.55936 27.1605
410 1KK8 BEF ADP 0.00003538 0.52746 27.2727
411 1GOT GDP 0.00000000002336 0.83588 27.7778
412 1GOJ ADP 0.0000001663 0.5321 27.7778
413 1RYH GNP 0.0000000143 0.68231 28.3951
414 4H1V GNP 0.0000004905 0.61645 28.3951
415 1GUA GNP 0.000000009407 0.72087 29.0123
416 4HDO GNP 0.00000001063 0.71824 29.0123
417 2FJU GSP 0.0000001099 0.65403 29.0123
418 1HE1 GDP 0.000000133 0.54146 29.0123
419 1HE1 AF3 0.009619 0.41108 29.0123
420 1FQJ GDP 0.0000000000197 0.84328 29.6296
421 1FQK GDP 0.00000000002974 0.83453 29.6296
422 1XTQ GDP 0.0000000005987 0.77071 29.6296
423 3T5G GDP 0.0000000004599 0.75289 29.6296
424 4DCT GDP 0.0000000006789 0.74029 29.6296
425 3SBD GNP 0.0000002755 0.49465 29.6296
426 1Y3A GDP 0.00000000002406 0.83904 30.2469
427 2OM2 GDP 0.00000000001808 0.83732 30.2469
428 1BH2 GSP 0.00000000006922 0.83288 30.2469
429 1GP2 GDP 0.00000000004515 0.82565 30.2469
430 5UFQ GNP 0.0000000006229 0.77633 30.2469
431 4DSU GDP 0.000000001218 0.76492 30.2469
432 1U8Z GDP 0.000000001936 0.74577 30.2469
433 5XCO GDP 0.000000001017 0.74088 30.2469
434 5KDO GDP 0.0000000000224 0.66162 30.2469
435 2ODE ALF GDP 0.0000000000241 0.85581 30.8642
436 1SVK ALF GDP 0.0000000000386 0.84854 30.8642
437 2WKQ GTP 0.0000001788 0.64958 30.8642
438 1I4D GDP 0.00000002569 0.64822 30.8642
439 2WJG GDP 0.0000000001454 0.76661 31.4815
440 2WJH GDP 0.0000000002308 0.76229 31.4815
441 1KMQ GNP 0.0000001957 0.64765 31.4815
442 2WJH FLC 0.000000141 0.63531 31.4815
443 2GCO GNP 0.00000007139 0.65653 32.0988
444 1VG1 GDP 0.00000000005337 0.79215 32.716
445 1VG8 GNP 0.0000000005146 0.78349 32.716
446 1Z0F GDP 0.0000000001781 0.76758 32.716
447 2D7C GTP 0.000000001158 0.76303 32.716
448 3RWO GDP 0.000000001282 0.76085 32.716
449 1VG9 GDP 0.000000000268 0.75924 32.716
450 1VG0 GDP 0.0000000004426 0.75808 32.716
451 2XTN GTP 0.000003855 0.5843 32.716
452 3T12 GDP ALF 0.00000000002877 0.83147 33.3333
453 3T1O GDP 0.00000000001351 0.82532 33.3333
454 1OIX GDP 0.0000000008551 0.76953 33.3333
455 1S8F GDP 0.000000001131 0.7694 33.3333
456 2HV8 GTP 0.000000001332 0.76003 33.3333
457 2A5J GDP 0.0000000004176 0.75487 33.3333
458 1Z0K GTP 0.000000001626 0.74948 33.3333
459 1E96 GTP 0.0000002196 0.65049 33.3333
460 1YZQ GNP 0.0000000005873 0.78064 33.9506
461 2FFQ GSP 0.000000000618 0.77955 33.9506
462 4C4P GNP 0.000000001157 0.76604 33.9506
463 1WA5 GTP 0.000000002247 0.76243 33.9506
464 1OIV GDP 0.00000000164 0.75556 33.9506
465 2BME GNP 0.000000002209 0.74917 33.9506
466 2F9L GDP 0.00000000236 0.74156 33.9506
467 2QZ4 ADP 0.00002034 0.53321 33.9506
468 2HT6 GDP 0.000000000002786 0.8218 34.5679
469 2CJW GDP 0.00000000003737 0.7941 34.5679
470 1Z2A GDP 0.0000000006783 0.76806 34.5679
471 5CK5 GDP 0.0000000006001 0.72031 34.5679
472 1G16 GDP 0.00000002419 0.68904 34.5679
473 1Z08 GNP 0.000000002298 0.74213 35.1852
474 3CX8 GSP 0.00000000006326 0.83484 35.8025
475 3AB3 GDP 0.0000000000467 0.81735 35.8025
476 1EK0 GNP 0.00000001053 0.71567 35.8025
477 3MJH GTP 0.0000000008363 0.77001 36.4198
478 1ZC3 GNP 0.000000002715 0.74765 36.4198
479 1NF3 GNP 0.0000002289 0.49483 36.4198
480 1TU3 GNP 0.0000000005495 0.77902 37.037
481 1R2Q GNP 0.00000000207 0.7714 37.037
482 3BC1 GNP 0.00000000136 0.75957 37.037
483 2A9K GDP 0.000000001283 0.74012 37.037
484 1Z0J GTP 0.00000000418 0.73835 37.037
485 1A4R GDP 0.00000003086 0.67744 37.037
486 1A4R GNH 0.000000046 0.66568 37.037
487 2NGR GDP 0.00000005513 0.65062 37.037
488 4DID GDP 0.00000005579 0.65038 37.037
489 4ITR GDP 0.0000001671 0.6421 37.037
490 1GRN GDP 0.000000146 0.64165 37.037
491 5HR5 ADP 0.00002914 0.5315 37.037
492 5HR5 FLC 0.006307 0.43855 37.037
493 1YVD GNP 0.000000004386 0.73445 37.6543
494 1KY3 GDP 0.000000004119 0.71197 37.6543
495 1YZN GNP 0.000000004736 0.73566 38.2716
496 2BCG GDP 0.000000001943 0.7353 38.2716
497 3RAB GNP 0.000000001263 0.76116 38.8889
498 2FH5 GTP 0.0000000001424 0.7939 39.5062
499 3QBT GNP 0.000000001653 0.75539 39.5062
500 2G77 GDP 0.0000000002796 0.77182 40.7407
501 1Z06 GNP 0.000000000671 0.77158 40.7407
502 1Z0A GDP 0.00000000008908 0.7866 42.5926
503 1D5C GDP 0.0000000002623 0.77314 42.5926
504 2QTV GNP 0.000000000289 0.78956 47.5309
505 1M2O GNP 0.0000000007519 0.77229 47.5309
506 1F6B GDP 0.000000000001152 0.87038 49.3827
Pocket No.: 2; Query (leader) PDB : 3N5C; Ligand: GDP; Similar sites found: 5
This union binding pocket(no: 2) in the query (biounit: 3n5c.bio1) has 17 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1QHG ATP 0.005855 0.41468 4.32099
2 4KVX ACO 0.02239 0.40053 4.48718
3 1JG3 ADN 0.016 0.41168 4.93827
4 1ME8 RVP 0.01726 0.41797 5.55556
5 3WQT ANP 0.01817 0.40053 17.9012
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