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Receptor
PDB id Resolution Class Description Source Keywords
1E3W 2 Å EC: 1.1.1.35 RAT BRAIN 3-HYDROXYACYL-COA DEHYDROGENASE BINARY COMPLEX WIT 3-KETO BUTYRATE RATTUS NORVEGICUS DEHYDROGENASE BETA-OXIDATION OF FATTY ACIDS STEROIDS AMYLBINDING
Ref.: RECOGNITION OF STRUCTURALLY DIVERSE SUBSTRATES BY T 3-HYDROXYACYL-COA DEHYDROGENASE (HADH II) AMYLOID-B BINDING ALCOHOL DEHYDROGENASE (ABAD) J.MOL.BIOL. V. 303 311 2000
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
AAE L:1;
Valid;
none;
submit data
102.089 C4 H6 O3 CC(=O...
NAD A:301;
B:301;
C:301;
D:301;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
submit data
663.425 C21 H27 N7 O14 P2 c1cc(...
SO4 L:2;
L:3;
L:7;
L:8;
L:9;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
submit data
96.063 O4 S [O-]S...
TRS L:4;
L:5;
L:6;
Invalid;
Invalid;
Invalid;
none;
none;
none;
submit data
122.143 C4 H12 N O3 C(C(C...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1E3W 2 Å EC: 1.1.1.35 RAT BRAIN 3-HYDROXYACYL-COA DEHYDROGENASE BINARY COMPLEX WIT 3-KETO BUTYRATE RATTUS NORVEGICUS DEHYDROGENASE BETA-OXIDATION OF FATTY ACIDS STEROIDS AMYLBINDING
Ref.: RECOGNITION OF STRUCTURALLY DIVERSE SUBSTRATES BY T 3-HYDROXYACYL-COA DEHYDROGENASE (HADH II) AMYLOID-B BINDING ALCOHOL DEHYDROGENASE (ABAD) J.MOL.BIOL. V. 303 311 2000
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 6 families.
1 1E3W - NAD C21 H27 N7 O14 P2 c1cc(c[n+]....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 5 families.
1 1E3W - NAD C21 H27 N7 O14 P2 c1cc(c[n+]....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 1E3W - NAD C21 H27 N7 O14 P2 c1cc(c[n+]....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: AAE; Similar ligands found: 8
No: Ligand ECFP6 Tc MDL keys Tc
1 AAE 1 1
2 MLA 0.6 0.631579
3 P2D 0.6 0.625
4 SHF 0.5 0.777778
5 PPI 0.470588 0.625
6 PYR 0.411765 0.625
7 BUQ 0.4 0.6
8 BUA 0.4 0.611111
Ligand no: 2; Ligand: NAD; Similar ligands found: 230
No: Ligand ECFP6 Tc MDL keys Tc
1 A3D 0.872727 0.986111
2 NHD 0.821429 0.972222
3 NAP 0.811966 0.986111
4 NFD 0.791304 0.946667
5 NXX 0.765766 0.972603
6 DND 0.765766 0.972603
7 AMP NAD 0.74359 0.972222
8 ZID 0.737705 0.986111
9 NAQ 0.729508 0.934211
10 NAE 0.721311 0.959459
11 NA0 0.712 0.972603
12 TAP 0.704 0.921053
13 NDE 0.689922 0.972603
14 NAJ 0.683333 0.972222
15 NDC 0.679389 0.934211
16 NDO 0.674603 0.958904
17 N01 0.656 0.972222
18 CNA 0.642276 0.972603
19 NBP 0.621212 0.922078
20 8ID 0.609756 0.922078
21 A2D 0.576923 0.958333
22 ADP 0.575472 0.931507
23 NGD 0.574803 0.922078
24 BA3 0.566038 0.958333
25 M33 0.564815 0.918919
26 ADP PO3 0.563636 0.957747
27 B4P 0.560748 0.958333
28 AP5 0.560748 0.958333
29 AN2 0.555556 0.918919
30 AT4 0.555556 0.894737
31 GAP 0.553571 0.932432
32 OOB 0.551724 0.972222
33 CA0 0.550459 0.932432
34 9JJ 0.546053 0.898734
35 HEJ 0.545455 0.931507
36 ACP 0.545455 0.906667
37 ATP 0.545455 0.931507
38 DQV 0.544 0.972222
39 ADP ALF 0.54386 0.883117
40 ALF ADP 0.54386 0.883117
41 DAL AMP 0.543103 0.945205
42 APR 0.540541 0.931507
43 AQP 0.540541 0.931507
44 AR6 0.540541 0.931507
45 5FA 0.540541 0.931507
46 ADP VO4 0.53913 0.945205
47 VO4 ADP 0.53913 0.945205
48 AD9 0.535714 0.906667
49 SAP 0.535714 0.883117
50 AGS 0.535714 0.883117
51 WAQ 0.533333 0.896104
52 ABM 0.53271 0.905405
53 DLL 0.529412 0.972222
54 00A 0.529412 0.921053
55 ACQ 0.526316 0.906667
56 NJP 0.526316 0.959459
57 ANP 0.526316 0.906667
58 OAD 0.525 0.932432
59 ADX 0.522523 0.839506
60 5AL 0.521739 0.945205
61 A1R 0.521008 0.871795
62 9SN 0.520325 0.909091
63 A 0.518868 0.930556
64 AMP 0.518868 0.930556
65 50T 0.517857 0.893333
66 ATF 0.517241 0.894737
67 1ZZ 0.516393 0.851852
68 3OD 0.516393 0.932432
69 SON 0.513514 0.92
70 PRX 0.513274 0.881579
71 6YZ 0.512821 0.906667
72 SRP 0.512821 0.92
73 9X8 0.512397 0.883117
74 ADP BMA 0.512397 0.932432
75 3UK 0.512397 0.958904
76 MYR AMP 0.512195 0.851852
77 NAJ PZO 0.510949 0.909091
78 NMN 0.509434 0.875
79 A3R 0.508333 0.871795
80 B5V 0.508197 0.945946
81 AMP DBH 0.507937 0.906667
82 A22 0.504202 0.945205
83 ATP A A A 0.504 0.971831
84 B5M 0.504 0.933333
85 FA5 0.504 0.945946
86 8QN 0.5 0.945205
87 NAX 0.496183 0.886076
88 TYR AMP 0.496063 0.933333
89 PR8 0.495935 0.8625
90 AMO 0.495868 0.92
91 ADQ 0.495868 0.932432
92 4AD 0.495868 0.933333
93 PAJ 0.495868 0.873418
94 A12 0.495495 0.894737
95 AP2 0.495495 0.894737
96 AHZ 0.492308 0.851852
97 YAP 0.492063 0.933333
98 FYA 0.491935 0.918919
99 AHX 0.491803 0.884615
100 4UU 0.488372 0.933333
101 5SV 0.487603 0.8375
102 TAT 0.487179 0.894737
103 T99 0.487179 0.894737
104 APC 0.486957 0.894737
105 SRA 0.486239 0.881579
106 6V0 0.484848 0.909091
107 NAI 0.484848 0.921053
108 GTA 0.484615 0.898734
109 A A 0.483871 0.958333
110 LAD 0.483871 0.873418
111 AU1 0.482456 0.906667
112 F2R 0.481752 0.831325
113 OMR 0.481203 0.841463
114 TXE 0.481203 0.921053
115 AF3 ADP 3PG 0.481203 0.873418
116 LAQ 0.480916 0.851852
117 G3A 0.48062 0.909091
118 B5Y 0.480315 0.933333
119 NB8 0.48 0.884615
120 TXA 0.48 0.92
121 BIS 0.48 0.871795
122 ME8 0.48 0.851852
123 PTJ 0.48 0.884615
124 139 0.477941 0.886076
125 LPA AMP 0.477273 0.851852
126 AFH 0.476923 0.873418
127 AR6 AR6 0.476923 0.958333
128 G5P 0.476923 0.909091
129 ARG AMP 0.476923 0.841463
130 25L 0.47619 0.945205
131 NAJ PYZ 0.475524 0.864198
132 25A 0.47541 0.958333
133 9ZA 0.47541 0.896104
134 9ZD 0.47541 0.896104
135 DZD 0.47482 0.897436
136 TXD 0.473684 0.921053
137 4UV 0.472868 0.933333
138 TYM 0.470149 0.945946
139 RBY 0.470085 0.894737
140 ADV 0.470085 0.894737
141 4TA 0.467626 0.864198
142 48N 0.466165 0.884615
143 XAH 0.465116 0.851852
144 4UW 0.462687 0.897436
145 M24 0.461538 0.886076
146 80F 0.460993 0.853659
147 IOT 0.459854 0.821429
148 T5A 0.456522 0.853659
149 EAD 0.455782 0.886076
150 MAP 0.455285 0.883117
151 GA7 0.454545 0.894737
152 BT5 0.453901 0.821429
153 A4P 0.452555 0.833333
154 UP5 0.451852 0.933333
155 PAP 0.445378 0.917808
156 4TC 0.445255 0.909091
157 AP0 0.445255 0.884615
158 YLP 0.444444 0.831325
159 P1H 0.443709 0.864198
160 AOC 0.442478 0.810811
161 Z5A 0.439189 0.833333
162 LMS 0.4375 0.817073
163 2A5 0.436975 0.857143
164 A G 0.43662 0.921053
165 G A A A 0.43662 0.909091
166 COD 0.43662 0.802326
167 ADJ 0.435714 0.841463
168 YLB 0.434783 0.831325
169 YLC 0.434783 0.851852
170 U A G G 0.433566 0.921053
171 ATR 0.433333 0.90411
172 7MD 0.432836 0.851852
173 8X1 0.432 0.764045
174 G5A 0.429752 0.790698
175 PO4 PO4 A A A A PO4 0.429688 0.943662
176 TAD 0.42963 0.873418
177 5AS 0.42735 0.770115
178 BTX 0.426573 0.831325
179 YLA 0.425532 0.831325
180 DSZ 0.425197 0.790698
181 NCN 0.424779 0.805556
182 UPA 0.42446 0.921053
183 8PZ 0.424242 0.811765
184 VMS 0.424 0.8
185 54H 0.424 0.8
186 9K8 0.423077 0.744444
187 N0B 0.422819 0.853659
188 6AD 0.422764 0.85
189 AYB 0.422535 0.821429
190 7D3 0.422414 0.844156
191 YLY 0.421769 0.821429
192 TSB 0.420635 0.809524
193 ODP 0.41958 0.922078
194 AV2 0.419355 0.855263
195 FB0 0.419355 0.775281
196 A5A 0.419355 0.819277
197 NNR 0.419048 0.739726
198 A A A 0.418605 0.918919
199 U A 0.417808 0.946667
200 649 0.417266 0.775281
201 NMN AMP PO4 0.416667 0.933333
202 SSA 0.416 0.790698
203 P5A 0.415385 0.755556
204 LSS 0.414062 0.772727
205 A2R 0.412698 0.918919
206 52H 0.412698 0.790698
207 JB6 0.412214 0.896104
208 5N5 0.411215 0.783784
209 YSA 0.410448 0.811765
210 53H 0.409449 0.790698
211 5CA 0.409449 0.790698
212 ITT 0.408333 0.878378
213 7D4 0.408333 0.844156
214 NA7 0.407692 0.894737
215 LEU LMS 0.407692 0.784091
216 5CD 0.407407 0.794521
217 0WD 0.406897 0.909091
218 A3P 0.40678 0.930556
219 HFD 0.406504 0.883117
220 AVV 0.40625 0.860759
221 RAB 0.40566 0.808219
222 XYA 0.40566 0.808219
223 ADN 0.40566 0.808219
224 FDA 0.405063 0.823529
225 GSU 0.40458 0.790698
226 7MC 0.404255 0.831325
227 NSS 0.403101 0.811765
228 6FA 0.402516 0.853659
229 PPS 0.4 0.817073
230 NVA LMS 0.4 0.784091
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1E3W; Ligand: NAD; Similar sites found with APoc: 933
This union binding pocket(no: 1) in the query (biounit: 1e3w.bio1) has 29 residues
No: Leader PDB Ligand Sequence Similarity
1 1LSS NAD None
2 1NPD NAD None
3 3BPX SAL None
4 1VI2 NAD None
5 3IWD M2T None
6 1VM6 NAD 0.877193
7 5OJL TXP 1.14943
8 1NYT NAP 1.14943
9 1C3V NDP 1.22449
10 1P19 IMP 1.35747
11 3OFK SAH 1.38889
12 5IN4 6CK 1.53257
13 5IN4 GDP 1.53257
14 5IN4 NAP 1.53257
15 1GV0 NAD 1.53257
16 1LTH NAD 1.53257
17 1GUZ NAD 1.53257
18 4PLG OXM 1.53257
19 4PLG NAI 1.53257
20 6GKV SAH 1.53257
21 3FPF MTA 1.53257
22 3FPF TNA 1.53257
23 1F8G NAD 1.53257
24 4N49 SAM 1.86916
25 3LU1 NAD 1.91571
26 9LDB NAD 1.91571
27 9LDT NAD 1.91571
28 6CEP NAD 1.91571
29 6CEP OXM 1.91571
30 2A92 NAI 1.91571
31 5UAO FAD 1.91571
32 1X7D ORN 1.91571
33 5T9F TYR 1.91571
34 1X7D NAD 1.91571
35 5T9F NAP 1.91571
36 6FDF SAH 1.91571
37 4D3F NAP 1.91571
38 4UZI IMD 1.91571
39 3C3Y SAH 2.1097
40 4ZU3 4SD 2.20264
41 3EW2 BTN 2.22222
42 1RPN NDP 2.29885
43 1V6A TRE 2.29885
44 5ZI2 NAD 2.29885
45 2C29 NAP 2.29885
46 4ZVV NAD 2.29885
47 5ZI2 ADP 2.29885
48 4ZVV GN0 2.29885
49 2C29 DQH 2.29885
50 3I6I NDP 2.29885
51 3ABI NAD 2.29885
52 3A06 NDP 2.29885
53 1V59 NAD 2.29885
54 3OJO NAD 2.29885
55 2NPX NAD 2.29885
56 2NPX FAD 2.29885
57 2YX1 SFG 2.29885
58 1PL6 572 2.29885
59 4D52 GXL 2.29885
60 1V59 FAD 2.29885
61 5J60 FAD 2.29885
62 5EOW FAD 2.29885
63 3A06 FOM 2.29885
64 2Q7V FAD 2.29885
65 1PL6 NAD 2.29885
66 1Q0H NDP 2.29885
67 1SQF SAM 2.29885
68 1Q0H FOM 2.29885
69 5XNC MTA 2.29885
70 5X20 NAD 2.29885
71 5LUB 3Y7 2.29885
72 2ZV2 609 2.29885
73 5ZZ6 ADP 2.40385
74 5ZZ6 NAD 2.40385
75 2DC1 NAD 2.54237
76 4GGZ BTN 2.6087
77 4GKV NAD 2.67857
78 1UXG NAD 2.68199
79 1UXG FUM 2.68199
80 2HK9 ATR 2.68199
81 1O6Z NAD 2.68199
82 1PJS NAD 2.68199
83 2CDU ADP 2.68199
84 1UWK URO 2.68199
85 1UWK NAD 2.68199
86 3O7W SAM 2.68199
87 2CDU FAD 2.68199
88 5X68 FAD 2.68199
89 1RYI GOA 2.68199
90 1RYI FAD 2.68199
91 3H9E NAD 2.68199
92 4NEC SAH 2.68199
93 1C0I FAD 2.68199
94 1C0I BE2 2.68199
95 1YQZ FAD 2.68199
96 1X87 NAD 2.68199
97 2HK9 NAP 2.68199
98 3VSE SAH 2.68199
99 5GUD NDP 2.68199
100 1YJQ NAP 2.68199
101 5N0J FAD 2.68199
102 3OND ADN 2.68199
103 3OND NAD 2.68199
104 4CJX NAP 2.68199
105 4MO2 FDA 2.68199
106 2OWZ CIT 2.68199
107 4LWP SAH 2.68199
108 5MBX FAD 2.68199
109 5MBX SP5 2.68199
110 4MO2 FAD 2.68199
111 5YU3 NAD 2.68199
112 5YU3 PRO 2.68199
113 4CNK FAD 2.68199
114 3EGI ADP 2.91262
115 3LCC SAH 2.97872
116 2UZH CDP 3.0303
117 5Y1G AKB 3.06513
118 5Y1G NAD 3.06513
119 1OC2 TDX 3.06513
120 1OC2 NAD 3.06513
121 1E7S NAP 3.06513
122 5X9D 80F 3.06513
123 3CMC NAD 3.06513
124 4XB2 NDP 3.06513
125 4XB2 HSE 3.06513
126 4J36 1HR 3.06513
127 4J36 FAD 3.06513
128 3NJ4 AFX 3.06513
129 4DPL NAP 3.06513
130 1I9G SAM 3.06513
131 3NJ4 NAD 3.06513
132 3T31 FAD 3.06513
133 3T31 DCQ 3.06513
134 5G3U ITW 3.06513
135 5JCA NDP 3.06513
136 5JCA FAD 3.06513
137 6GAR FAD 3.06513
138 5G3U FDA 3.06513
139 2BRY FAD 3.06513
140 1I8T FAD 3.06513
141 6C4N NAP 3.06513
142 4TXI FAD 3.06513
143 2VTD LKM 3.06513
144 3C1O NAP 3.06513
145 4IV9 FAD 3.06513
146 3BAZ NAP 3.06513
147 2Q0L FAD 3.06513
148 2WET FAD 3.06513
149 3BJE URA 3.06513
150 2EG5 SAH 3.06513
151 5UAV TFB 3.06513
152 5ZBC FAD 3.06513
153 3WBF API 3.06513
154 2RGJ FAD 3.06513
155 5D4V SAH 3.06513
156 3X0V FAD 3.06513
157 5AYV NAP 3.06513
158 5MPT SAH 3.06513
159 5UAV NDP 3.06513
160 1CDO NAD 3.06513
161 2ZWA SAH 3.06513
162 2AK3 AMP 3.09735
163 3MB5 SAM 3.13725
164 1J5P NAD 3.16206
165 1UKG MMA 3.1746
166 3MQ2 SAH 3.21101
167 4KP7 NAP 3.27869
168 4KP7 1UQ 3.27869
169 5LXB 7A9 3.30579
170 1EJ0 SAM 3.33333
171 2R4J FAD 3.39321
172 2R4J 13P 3.39321
173 4ZRN NAD 3.44828
174 4ZRN UPG 3.44828
175 1RKX NAD 3.44828
176 3WMX NAD 3.44828
177 4Q9N NAI 3.44828
178 6EL3 NAP 3.44828
179 5KKA 6V0 3.44828
180 2F1K NAP 3.44828
181 3H8V ATP 3.44828
182 1HYH NAD 3.44828
183 2VUT NAD 3.44828
184 4C4A SAH 3.44828
185 5JAQ NAI 3.44828
186 6A0S HSE 3.44828
187 6A0S NDP 3.44828
188 4RPL 3UC 3.44828
189 4RPL FAD 3.44828
190 5Y77 FAD 3.44828
191 4KOA NDP 3.44828
192 5TWB FAD 3.44828
193 2ZXI FAD 3.44828
194 1LVL NAD 3.44828
195 5BUK FAD 3.44828
196 5Z2F NAP 3.44828
197 6AIN FAD 3.44828
198 4FWE FAD 3.44828
199 5XVH NAP 3.44828
200 1TB4 PEJ 3.44828
201 2WK1 SAH 3.44828
202 5AOV NAP 3.44828
203 1D1T NAD 3.44828
204 3EVG SAH 3.44828
205 4YCA NDP 3.44828
206 1TI7 NAP 3.44828
207 2WTN FER 3.58566
208 2GN4 UD1 3.83142
209 2GN4 NDP 3.83142
210 4GLL NAD 3.83142
211 4OHU NAD 3.83142
212 4OHU 2TK 3.83142
213 2YY7 NAD 3.83142
214 5K4W NAI 3.83142
215 5K4W THR 3.83142
216 1V35 NAI 3.83142
217 5MLR NAP 3.83142
218 5MLR GRQ 3.83142
219 2V6G NAP 3.83142
220 5F5N NAD 3.83142
221 2GZ3 NAP 3.83142
222 3GGO NAI 3.83142
223 3GGO ENO 3.83142
224 1RM0 D6P 3.83142
225 1RM0 NAI 3.83142
226 1KYZ SAH 3.83142
227 3WGT FAD 3.83142
228 3WGT QSC 3.83142
229 1E1M FAD 3.83142
230 1E1M NAP 3.83142
231 1MUU NAD 3.83142
232 3AYI HCI 3.83142
233 3AYI FAD 3.83142
234 1GAD NAD 3.83142
235 2AQJ FAD 3.83142
236 2AQJ TRP 3.83142
237 1J0X NAD 3.83142
238 2ZJ1 NAD 3.83142
239 2ZJ1 ARJ 3.83142
240 2PT9 2MH 3.83142
241 4R5M 4NO 3.83142
242 1FP1 SAH 3.83142
243 2I7C AAT 3.83142
244 1O0S NAI 3.83142
245 1MV8 NAD 3.83142
246 4M37 SAH 3.83142
247 3QJ4 FAD 3.83142
248 1DSS NAD 3.83142
249 2G5C NAD 3.83142
250 3GCZ SAM 3.83142
251 5J5Z FAD 3.83142
252 2PT9 S4M 3.83142
253 6A3J NAI 3.83142
254 5WGR FAD 3.83142
255 5Y8L NAD 3.83142
256 5Y8L HUI 3.83142
257 4R5M NAP 3.83142
258 1FEC FAD 3.83142
259 4JNA FAD 3.83142
260 2GMH FAD 3.83142
261 2F5Z FAD 3.83142
262 5BRT FAD 3.83142
263 5BRT CH9 3.83142
264 2DBZ NAP 3.83142
265 2PWY SAH 3.87597
266 2VDV SAM 4.06504
267 2XYQ SAH 4.09836
268 3WV8 ATP 4.12844
269 3BXO SAM 4.1841
270 3NYC FAD 4.19948
271 3NYC IAR 4.19948
272 4D42 NAP 4.21456
273 4D42 W0I 4.21456
274 2PD4 NAD 4.21456
275 2PD4 DCN 4.21456
276 5MSO NAP 4.21456
277 5MDH NAD 4.21456
278 4MDH NAD 4.21456
279 1T26 GBD 4.21456
280 1T26 NAI 4.21456
281 1LDM NAD 4.21456
282 1EZ4 NAD 4.21456
283 3V1Y NAD 4.21456
284 1VKO NAD 4.21456
285 3CGB FAD 4.21456
286 5JWC FAD 4.21456
287 3ZNN 4WL 4.21456
288 3ZNN FAD 4.21456
289 5BVA FAD 4.21456
290 2IZ1 ATR 4.21456
291 3TWO NDP 4.21456
292 3L9W AMP 4.21456
293 2IXB A2G 4.21456
294 1YKJ FAD 4.21456
295 1YKJ PHB 4.21456
296 4Z0H NAD 4.21456
297 4EIP FAD 4.21456
298 2NAD NAD 4.21456
299 3I7S PYR 4.21456
300 4K5S FAD 4.21456
301 6F97 FAD 4.21456
302 4K5S PM0 4.21456
303 2IXB NAD 4.21456
304 3Q9T FAY 4.21456
305 1OMO NAD 4.21456
306 1A99 PUT 4.21456
307 5KAX RHQ 4.21687
308 1JAY NAP 4.24528
309 4OBW SAM 4.28016
310 2Q46 NAP 4.34783
311 1DRV A3D 4.3956
312 3G89 SAM 4.41767
313 1VL0 NAI 4.5977
314 3RFV NAI 4.5977
315 2PZM UDP 4.5977
316 2PZM NAD 4.5977
317 3RFV 15L 4.5977
318 2HJR APR 4.5977
319 1A5Z NAD 4.5977
320 5NUF NAD 4.5977
321 5NUE NAD 4.5977
322 2UYQ SAM 4.5977
323 2VYN NAD 4.5977
324 1H2B NAJ 4.5977
325 1SOW NAD 4.5977
326 4B4U NAP 4.5977
327 5OC1 FAD 4.5977
328 2JHF NAD 4.5977
329 3A70 NPO 4.5977
330 1NVM NAD 4.5977
331 4M52 FAD 4.5977
332 3H5N ATP 4.5977
333 2JJQ SAH 4.5977
334 5EZ7 FAD 4.5977
335 2I3G NAP 4.5977
336 2JHP SAH 4.5977
337 2EV9 NAP 4.5977
338 2EV9 SKM 4.5977
339 5TTJ FAD 4.5977
340 6AC9 ANP 4.5977
341 2RGO FAD 4.5977
342 5EIN NAP 4.5977
343 4XZ3 ACP 4.5977
344 4M00 SUC 4.5977
345 5U5N NAD 4.5977
346 5YSN 5AD 4.5977
347 1M6P M6P 4.60526
348 1RL4 BL5 4.78723
349 1N7G NDP 4.98084
350 2Q1W NAD 4.98084
351 1N7G GDR 4.98084
352 4RSL FAD 4.98084
353 4D79 ATP 4.98084
354 5UR0 NAD 4.98084
355 2PV7 NAD 4.98084
356 1HYE NAP 4.98084
357 3B1J NAD 4.98084
358 1GZ4 ATP 4.98084
359 5WP5 SAH 4.98084
360 4RDH AMP 4.98084
361 2JL1 NAP 4.98084
362 5MZI FAD 4.98084
363 5MZI FYK 4.98084
364 3CTY FAD 4.98084
365 3B20 NAD 4.98084
366 6ER9 NAP 4.98084
367 5TC4 NAD 4.98084
368 4RDI ATP 4.98084
369 6ER9 FAD 4.98084
370 5Z20 NAI 4.98084
371 1GR0 NAD 4.98084
372 4D04 FAD 4.98084
373 4D04 NAP 4.98084
374 2ZIF SAM 4.98084
375 5GSN FAD 4.98084
376 5GSN MMZ 4.98084
377 5GSN NAP 4.98084
378 2YG3 FAD 4.98084
379 2D2I NAP 4.98084
380 1CF2 NAP 4.98084
381 4Z28 BTN 5.22388
382 1KEW NAD 5.36398
383 1KEW TYD 5.36398
384 2Q1S NAI 5.36398
385 5ZEC NAP 5.36398
386 1D7O NAD 5.36398
387 1D7O TCL 5.36398
388 5L4L NAP 5.36398
389 5L4L 7OX 5.36398
390 2QRK AMP 5.36398
391 1BW9 NAD 5.36398
392 5O9F NAD 5.36398
393 5O9F 9ON 5.36398
394 5VN0 FAD 5.36398
395 3X0D SAH 5.36398
396 1GTE FAD 5.36398
397 1D4D FAD 5.36398
398 5OCM NAP 5.36398
399 1E5Q NDP 5.36398
400 5N6C NAD 5.36398
401 3HDY FAD 5.36398
402 1DLJ UGA 5.36398
403 1DLJ NAI 5.36398
404 3E1T FAD 5.36398
405 3HDY GDU 5.36398
406 3HDY FDA 5.36398
407 5YAP NAI 5.36398
408 3FPZ AHZ 5.36398
409 1C1X NAD 5.36398
410 4IDT T28 5.36398
411 3K7M FAD 5.36398
412 6CGZ HL6 5.36398
413 3KLJ FAD 5.36398
414 5YAP 8S0 5.36398
415 1BXG NAD 5.36398
416 5VN0 NAI 5.36398
417 1EYQ NAR 5.40541
418 4Z7X 3CX 5.46218
419 3JWH SAH 5.52995
420 5WQP NAP 5.55556
421 5WQP NCA 5.55556
422 4BQS K2Q 5.68182
423 1XHC FAD 5.72207
424 6BWL NAD 5.74713
425 3OIG NAD 5.74713
426 5DF1 58X 5.74713
427 5DF1 NAP 5.74713
428 3ICT ADP 5.74713
429 3ICS ADP 5.74713
430 2CVQ NDP 5.74713
431 4II2 ATP 5.74713
432 1B8U OAA 5.74713
433 4MIG G3F 5.74713
434 3ICT FAD 5.74713
435 3L4S NAD 5.74713
436 1B8U NAD 5.74713
437 4DMG SAM 5.74713
438 4MOP 2H5 5.74713
439 5H81 NAP 5.74713
440 3B1F NAD 5.74713
441 5WP4 SAH 5.74713
442 2VVM FAD 5.74713
443 2B4R NAD 5.74713
444 3L4S 3PG 5.74713
445 1REO FAD 5.74713
446 2IID FAD 5.74713
447 2IID PHE 5.74713
448 3NT6 FAD 5.74713
449 2B4R AES 5.74713
450 3ICS FAD 5.74713
451 5TS5 FAD 5.74713
452 3ICR FAD 5.74713
453 2VVL FAD 5.74713
454 4AP3 FAD 5.74713
455 4AP3 NAP 5.74713
456 1EBF NAD 5.74713
457 3KB6 NAD 5.74713
458 3UOY FAD 5.74713
459 3UOY NAP 5.74713
460 1WP4 NDP 5.74713
461 6BII NAP 5.74713
462 4YUW 4JU 5.74713
463 2CDC XYP 5.74713
464 5XLX SAH 5.74713
465 3UCL CYH 5.74713
466 3UCL FAD 5.74713
467 2CDC XYS 5.74713
468 3GMB FAD 5.74713
469 4YUW S4M 5.74713
470 2CDC NAP 5.74713
471 2CVZ NDP 5.74713
472 5CAE COA 5.7508
473 5CAE SIN 5.7508
474 5FI3 NAP 5.88235
475 1M0S CIT 5.93607
476 4R1S NAP 6.13027
477 3KO8 NAD 6.13027
478 1WVG APR 6.13027
479 1KYQ NAD 6.13027
480 5DNK SAH 6.13027
481 2VHW NAI 6.13027
482 5HSA FAS 6.13027
483 1H82 GZZ 6.13027
484 1H82 FAD 6.13027
485 4YRY NAD 6.13027
486 4YRY FAD 6.13027
487 4GUT FAD 6.13027
488 4HSU FAD 6.13027
489 4GUS FAD 6.13027
490 5NMX NAP 6.13027
491 6FP4 FAD 6.13027
492 5KMS NAD 6.13027
493 5NMX FAD 6.13027
494 2GSD NAD 6.13027
495 1QO8 FAD 6.13027
496 6FP4 E1T 6.13027
497 5OOH NAP 6.31068
498 5OOH 9ZZ 6.31068
499 2OOR NAD 6.32184
500 3WLE NAD 6.45161
501 1XSE NDP 6.51341
502 2X6T NAP 6.51341
503 1EQ2 NAP 6.51341
504 2PK3 A2R 6.51341
505 1UDB UFG 6.51341
506 1UDB NAD 6.51341
507 4OOE FOM 6.51341
508 4OOE NDP 6.51341
509 3QV1 NAD 6.51341
510 1SAY PYR 6.51341
511 1ZGA SAH 6.51341
512 4X9M FAD 6.51341
513 4LHD GLY 6.51341
514 5F8F SFG 6.51341
515 5FJN FAD 6.51341
516 5FJN BE2 6.51341
517 2WA2 SAM 6.51341
518 1Y8Q ATP 6.51341
519 2C7G ODP 6.51341
520 2C7G FAD 6.51341
521 4UP4 NAG 6.51341
522 4UP4 NDG 6.51341
523 4BVA NDP 6.51341
524 2C5A GDC 6.89655
525 2C5A NAD 6.89655
526 1I2B NAD 6.89655
527 1I2B USQ 6.89655
528 1I2B UPG 6.89655
529 3OA2 NAD 6.89655
530 6AA8 NAD 6.89655
531 3AXB FAD 6.89655
532 3AXB PRO 6.89655
533 3SSO SAH 6.89655
534 5JY6 NAD 6.89655
535 3PT9 SAH 6.89655
536 1YY5 FAD 6.89655
537 1RSG FAD 6.89655
538 5JE8 NAD 6.89655
539 5M67 NAD 6.89655
540 5M67 3D1 6.89655
541 5M67 ADE 6.89655
542 1GQ2 NAP 6.89655
543 2GV8 FAD 6.89655
544 4ZCC NAI 6.89655
545 4ZCC FAD 6.89655
546 1VQW FAD 6.89655
547 2GVC FAD 6.89655
548 5E9G GLV 6.89655
549 4NTC FAD 6.89655
550 3AD8 PYC 7.07071
551 3AD8 FAD 7.07071
552 3AD8 NAD 7.07071
553 1SB8 UD2 7.27969
554 1SB8 NAD 7.27969
555 5BJX NAD 7.27969
556 5BJX UDP 7.27969
557 4PIV NDP 7.27969
558 5NA1 FAD 7.27969
559 5DN9 NAD 7.27969
560 1V8B NAD 7.27969
561 1J49 NAD 7.27969
562 1NVT NAP 7.27969
563 2IVD FAD 7.27969
564 4NTD FAD 7.27969
565 3TKY SAH 7.27969
566 2HYQ MAN MAN 7.37705
567 2NU5 NAG 7.37705
568 2GUC MAN 7.37705
569 2GUD MAN 7.37705
570 2GUD BMA 7.37705
571 2NUO BGC 7.37705
572 2ZFU SAH 7.44186
573 2XVM SAH 7.53769
574 2DT5 NAD 7.58294
575 6DNT NAD 7.66284
576 1R6D NAD 7.66284
577 1R6D DAU 7.66284
578 3G5S FAD 7.66284
579 4OPC PGT 7.66284
580 4OPC FDA 7.66284
581 4WOE 3S5 7.66284
582 1PS9 FAD 7.66284
583 1PS9 NAP 7.66284
584 3QVP FAD 7.66284
585 3AB1 FAD 7.66284
586 5U8U FAD 7.66284
587 5TOW NAI 7.66284
588 5TOW ADN 7.66284
589 5YEC ATP 7.66284
590 1LC3 NAD 7.66284
591 4B7X NAP 7.66284
592 5C9P FUC 7.66284
593 4J4H NAI 7.72201
594 4J4H 1J1 7.72201
595 4JK3 NAD 7.72201
596 2CUL FAD 7.75862
597 5N2I NAP 7.75862
598 1HDR NAD 7.78689
599 4HXY NDP 8.04598
600 5LD5 NAD 8.04598
601 4HXY ACA 8.04598
602 3VPH NAD 8.04598
603 3O9Z AKG 8.04598
604 3O9Z NAD 8.04598
605 3VPH OXM 8.04598
606 1HDG NAD 8.04598
607 3CIF NAD 8.04598
608 3CIF G3H 8.04598
609 3NTA FAD 8.04598
610 3NTD FAD 8.04598
611 5J7X FAD 8.04598
612 3CQ5 PMP 8.04598
613 4E5N NAD 8.04598
614 1BZL GCG 8.04598
615 1BZL FAD 8.04598
616 6BQ6 TER 8.04598
617 1R37 NAD 8.35735
618 5I7S E9P 8.42912
619 5I7S NAD 8.42912
620 2DKH FAD 8.42912
621 2DKH 3HB 8.42912
622 1DJN ADP 8.42912
623 2Y6Q I7T 8.42912
624 2Y6Q FAD 8.42912
625 4L8V NAP 8.42912
626 1O94 ADP 8.42912
627 5KOX FAD 8.42912
628 5KOX RFP 8.42912
629 1LUA NAP 8.42912
630 2XVF FAD 8.42912
631 2WPF FAD 8.42912
632 2WPF WPF 8.42912
633 5A1T NAI 8.5044
634 5A1T OXM 8.5044
635 4YSX FAD 8.51064
636 5T2Y 753 8.58586
637 5XWV 8H6 8.66935
638 5XWV NDP 8.66935
639 2BKA NDP 8.67769
640 4REP FAD 8.68687
641 2QZZ NAP 8.80503
642 2QZZ EMF 8.80503
643 5Z75 NAD 8.81226
644 1LDN NAD 8.81226
645 3GF4 UPG 8.81226
646 3GF4 FAD 8.81226
647 6GAS FAD 8.81226
648 6C4T NA7 8.81226
649 1CT9 GLN 8.81226
650 1FP2 SAH 8.81226
651 2YVJ NAI 8.81226
652 5K0A FAD 8.81226
653 4BG4 ARG 8.81226
654 2B5W NAP 8.81226
655 1YS4 NAP 8.81226
656 3BRN SRO 8.9172
657 4TQG NDP 9.1954
658 2EXX NAP 9.1954
659 4PLT NAI 9.1954
660 4PLT OXM 9.1954
661 2B9J ADP 9.1954
662 4CCK OGA 9.1954
663 1RM4 NDP 9.1954
664 2B9I ADP 9.1954
665 1Y1P NMN AMP PO4 9.57854
666 1P77 ATR 9.57854
667 4DSG UDP 9.57854
668 4DSG FAD 9.57854
669 5Z21 NAI 9.57854
670 1ZQ9 SAM 9.57854
671 2YAB AMP 9.57854
672 2RAB NAD 9.57854
673 2RAB FAD 9.57854
674 1QAN SAH 9.83607
675 1U1I NAD 9.96169
676 2DFV NAD 9.96169
677 4J56 FAD 9.96169
678 4U8P FDA 10.3448
679 3IHG FAD 10.3448
680 4U8P UDP 10.3448
681 2HMT NAI 10.4167
682 4U7W NDP 10.728
683 1LLU NAD 10.728
684 2E5V FAD 10.728
685 5EES NAP 10.9312
686 1GY8 NAD 11.1111
687 3GFB NAD 11.1111
688 4ZGS NAD 11.1111
689 5HJM MTA 11.1111
690 5L95 AMP 11.25
691 4PVD NDP 11.4943
692 2XVE FAD 11.4943
693 1KOL NAD 11.4943
694 1GPE FAD 11.4943
695 5KVS NAP 11.4943
696 1E6E FAD 11.7188
697 1ORR NAD 11.8774
698 5ZYN FAD 11.8774
699 1U3U BNF 11.8774
700 1U3U NAD 11.8774
701 2QA1 FAD 11.8774
702 4POO SAM 12
703 3RNM FAD 12.069
704 1I36 NAP 12.2605
705 4Q6R SIN 12.2605
706 3A4V PYR 12.6437
707 3A4V NAD 12.6437
708 2HYV UAP SGN IDS SGN IDS 12.6437
709 1H9A NAP 12.6437
710 2Z3Y F2N 12.6437
711 1P0F NAP 12.6437
712 5CG1 NAD BBN 13.0268
713 1CER NAD 13.0268
714 2FZW NAD 13.0268
715 3GU3 SAH 13.0268
716 2JB2 PHE 13.0268
717 2JB2 FAD 13.0268
718 1NNU NAD 13.3333
719 1NNU TCT 13.3333
720 2CHT TSA 13.3858
721 1PZG A3D 13.41
722 1HKU NAD 13.41
723 1QG6 NAD 13.7931
724 1QG6 TCL 13.7931
725 3CGD NAD 14.5594
726 3CGD COA 14.5594
727 3CGD FAD 14.5594
728 4E13 NAD 14.5594
729 2WG9 OCA 14.6154
730 1E3I CXF 14.9425
731 1GET NAP 14.9425
732 1GET FAD 14.9425
733 4JDR FAD 14.9425
734 5L4S 6KX 15.3257
735 5L4S NAP 15.3257
736 4RQU NAD 15.3257
737 2VT3 ATP 15.3488
738 5GT9 NAP 15.7088
739 1JNR FAD 15.7088
740 3WQQ NDP 15.7088
741 3WQQ IB3 15.7088
742 4EUE NAI 16.092
743 5E9W SAH 16.092
744 4OM8 NAD 16.092
745 5O98 NAP 16.4751
746 3O26 NDP 16.8582
747 4O1M NAD 16.8582
748 4W6Z 8ID 17.2414
749 4JNJ BTN 17.3913
750 1Z45 NAD 17.6245
751 2FR1 NDP 18.0077
752 1WMA AB3 18.3908
753 1WMA NDP 18.3908
754 4G5H UD7 18.3908
755 4G5H NAP 18.3908
756 3OJF IMJ 19.0661
757 3OJF NDP 19.0661
758 4XQC 13D 19.1571
759 4XQC NAD 19.1571
760 4MP8 NAD 19.1571
761 4MP8 MLI 19.1571
762 1BXK NAD 19.5402
763 1FK8 NAD 19.8444
764 4YEF 4CQ 20.2247
765 1EK6 NAI 21.0728
766 1EK6 UPG 21.0728
767 1N5D NDP 21.8391
768 2GAG FAD 22.2222
769 2GAG FOA 22.2222
770 5I39 FAD 22.2222
771 2GAG NAD 22.2222
772 3TN7 NJP 22.5681
773 5E8J SAH 22.7273
774 1SC6 NAD 24.1379
775 5L53 NAP 24.5211
776 4JLS 3ZE 26.3158
777 3LZW FAD 26.8199
778 3LZW NAP 26.8199
779 3ORF NAD 29.8805
780 1SNY NAP 29.8851
781 4J1Q NDP 30.2682
782 2BD0 NAP 30.3279
783 1Z6Z NAP 31.2057
784 4K26 NDP 31.4176
785 4K26 SFF 31.4176
786 4Y9D NAI 31.8008
787 4GQB 0XU 31.8182
788 1OAA OAA 32.4324
789 4J7U YTZ 32.6389
790 4J7U NAP 32.6389
791 3CH6 NAP 33.3333
792 3CH6 311 33.3333
793 4M38 SAH 33.3333
794 1BDB NAD 33.7165
795 4YAC NAI 34.0996
796 3RKR NAP 34.0996
797 4YAG NAI 34.4828
798 3RJ5 NAD 34.6457
799 3HB5 NAP 34.8659
800 1A27 NAP 34.8659
801 5FA5 MTA 35
802 3ZV6 4HB 35.249
803 3ZV6 NAD 35.249
804 1XG5 NAP 35.249
805 1O5I NAD 35.3414
806 5B4T NAD 35.7692
807 5B4T 3HR 35.7692
808 3WXB NDP 36.0153
809 3AI3 SOL 36.7816
810 5GWT NAD 37.1647
811 5GWT SIN 37.1647
812 1W8D NAP 37.1647
813 1W73 NAP 37.1647
814 2JAH NDP 37.247
815 3U4C NDP 37.5479
816 1GZ6 NAI 37.931
817 1H5Q NAP 38.1132
818 1W6U NAP 38.6973
819 2BGM NAJ 39.2086
820 2JAP NDP 39.6761
821 1MXH DHF 40.2299
822 5EPO NAP 40.2299
823 1MXH NAP 40.2299
824 5EPO TUD 40.2299
825 5YSS NAD 40.2344
826 4KWI NAP 40.9962
827 4KWI 1TJ 40.9962
828 4O0L NDP 41.0909
829 2WYV NAD 41.3793
830 3AFN NAP 41.4729
831 2DKN NAI 41.5686
832 6CI9 NAP 41.6988
833 6CI9 F3V 41.6988
834 3V1U NAD 41.7625
835 1X1T NAD 41.9231
836 5G4L NDP 42.1456
837 2VZ0 D64 42.1456
838 2VZ0 NAP 42.1456
839 4CM9 NAP 42.1456
840 5K6A NAP 42.1456
841 3BMN NAP 42.1456
842 5JDC NAP 42.1456
843 4CLR NAP 42.1456
844 2WD7 NAP 42.1456
845 4CMI NAP 42.1456
846 5JCJ NAP 42.1456
847 5JDI NAP 42.1456
848 3BMO NAP 42.1456
849 3JQF NAP 42.1456
850 4CM8 NAP 42.1456
851 3JQA NAP 42.1456
852 4CM4 NAP 42.1456
853 3BMQ NAP 42.1456
854 3JQ9 NAP 42.1456
855 3JQG NAP 42.1456
856 3JQ7 NAP 42.1456
857 4CLO NAP 42.1456
858 4CME NAP 42.1456
859 3JQB NAP 42.1456
860 3JQ8 NAP 42.1456
861 3H4V DVP 42.1456
862 3H4V NAP 42.1456
863 5JDI 6JO 42.1456
864 5JCJ 6JM 42.1456
865 4CM9 YGL 42.1456
866 3JQ8 DX3 42.1456
867 4CME KTZ 42.1456
868 3JQB DX6 42.1456
869 3OID NDP 42.2481
870 3OID TCL 42.2481
871 2RH4 EMO 42.5287
872 3SJU NDP 42.5287
873 5OVL NAP 42.5287
874 1PR9 NAP 42.623
875 3D3W NAP 42.623
876 5WUW NAP 42.9119
877 2ZAT NAP 43.0769
878 4OSP NAP 43.295
879 5OVK NDP 43.3594
880 2WSB NAD 43.7008
881 1JA9 NDP 43.7956
882 1JA9 PYQ 43.7956
883 3ICC NAP 43.9216
884 2Q2V NAD 44.3137
885 5THQ NDP 44.4853
886 5Z2L NDP 44.4898
887 1XHL NDP 44.8276
888 4FC7 NAP 44.8276
889 4FC7 COA 44.8276
890 1YXM ADE 44.8276
891 1XHL TNE 44.8276
892 4ITU NAI 44.9814
893 4ITU 1HS 44.9814
894 1G0N PHH 45.2107
895 1G0N NDP 45.2107
896 3GEG NAD 45.3441
897 5FEU NAP 45.5939
898 5EJ2 NAD 45.5939
899 1ZEM NAD 45.5939
900 2AG5 NAD 45.935
901 2B4Q NAP 45.977
902 3QWI CUE 46.3602
903 3QWI NAP 46.3602
904 2EWM NAD 46.5863
905 5O42 NAD 46.7153
906 5O42 BGC 46.7153
907 5O42 9JW 46.7153
908 4RF2 NAP 46.7433
909 3O03 NAP 46.7433
910 4QED NAP 46.7742
911 5FFF NAP 47.0817
912 5FFF 5XC 47.0817
913 1XKQ NDP 47.1264
914 2GDZ NAD 47.8927
915 1GEG NAD 48.0469
916 3NUG NAD 48.1781
917 1UZN NAP 48.1781
918 3VZS CAA 48.249
919 3VZS NAP 48.249
920 1AE1 NAP 48.2759
921 4JP3 CIT 48.954
922 4ZA2 NAD 49.0119
923 6F9Q NAD 49.0421
924 2AE2 PTO 49.2308
925 2AE2 NAP 49.2308
926 1ZK4 NAP 49.4024
927 1ZK4 AC0 49.4024
928 2DTX BMA 49.4253
929 5T2U NAP 49.5968
930 1NFQ NAI 49.6154
931 4NBW NAD 49.8054
932 3AY6 NAI 49.8084
933 3AY6 BGC 49.8084
934 5OJI NAP 50
935 5OJI ISN 50
Pocket No.: 2; Query (leader) PDB : 1E3W; Ligand: NAD; Similar sites found with APoc: 201
This union binding pocket(no: 2) in the query (biounit: 1e3w.bio1) has 31 residues
No: Leader PDB Ligand Sequence Similarity
1 1QSC ACE TYR PRO ILE GLN GLU THR None
2 5T9E NAP None
3 5O4J 9KH 1.14943
4 5O4J SAH 1.14943
5 5O4J PJL 1.14943
6 2HNK SAH 1.25523
7 6F5Z SAH 1.2987
8 2EFJ SAH 1.53257
9 3A27 SAM 1.53257
10 5BW4 SAM 1.91571
11 1U2Z SAH 1.91571
12 5GM1 SAH 1.91571
13 5DOZ NDP 1.91571
14 5O96 SAM 2.04082
15 4IWN GEK 2.18341
16 3GUZ PAF 2.27273
17 3LST SAH 2.29885
18 3T7S SAM 2.29885
19 3VPD CIT 2.29885
20 4KRI SAH 2.29885
21 3FUU ADN 2.29885
22 6ECU SAH 2.29885
23 6ECW SAH 2.29885
24 2QQF A1R 2.29885
25 1F3L SAH 2.29885
26 5KVA SAM 2.29885
27 2PXX SAH 2.32558
28 5FA8 SAM 2.48447
29 3G2O SAM 2.68199
30 1G55 SAH