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Receptor
PDB id Resolution Class Description Source Keywords
1E7R 1.6 Å EC: 5.1.3.- GDP 4-KETO-6-DEOXY-D-MANNOSE EPIMERASE REDUCTASE Y136E ESCHERICHIA COLI EPIMERASE REDUCTASE SDR RED ISOMERASE
Ref.: PROBING THE CATALYTIC MECHANISM OF GDP-4-KETO-6-DEOXY-D-MANNOSE EPIMERASE/REDUCTASE BY KINETIC AND CRYSTALLOGRAPHIC CHARACTERIZATION OF SITE-SPECIFIC MUTANTS J.MOL.BIOL. V. 303 77 2000
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
NAP A:1317;
Valid;
none;
submit data
743.405 C21 H28 N7 O17 P3 c1cc(...
SO4 A:1320;
A:1321;
Invalid;
Invalid;
none;
none;
submit data
96.063 O4 S [O-]S...
TRS A:1319;
A:1322;
Invalid;
Invalid;
none;
none;
submit data
122.143 C4 H12 N O3 C(C(C...
UVW A:1318;
Invalid;
none;
submit data
140.032 C2 H5 O5 P CC(=O...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1E7S 1.5 Å EC: 5.1.3.- GDP 4-KETO-6-DEOXY-D-MANNOSE EPIMERASE REDUCTASE K140R ESCHERICHIA COLI EPIMERASE/REDUCTASE SDR RED
Ref.: PROBING THE CATALYTIC MECHANISM OF GDP-4-KETO-6-DEOXY-D-MANNOSE EPIMERASE/REDUCTASE BY KINETIC AND CRYSTALLOGRAPHIC CHARACTERIZATION OF SITE-SPECIFIC MUTANTS J.MOL.BIOL. V. 303 77 2000
Members (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 7 families.
1 1E7R - NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
2 1E7S - NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
3 1FXS - NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
4 1BWS - NDP C21 H30 N7 O17 P3 c1nc(c2c(n....
5 1BSV - NDP C21 H30 N7 O17 P3 c1nc(c2c(n....
70% Homology Family (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 7 families.
1 1E7R - NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
2 1E7S - NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
3 1FXS - NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
4 1BWS - NDP C21 H30 N7 O17 P3 c1nc(c2c(n....
5 1BSV - NDP C21 H30 N7 O17 P3 c1nc(c2c(n....
50% Homology Family (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 1E7R - NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
2 1E7S - NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
3 1FXS - NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
4 1BWS - NDP C21 H30 N7 O17 P3 c1nc(c2c(n....
5 1BSV - NDP C21 H30 N7 O17 P3 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: NAP; Similar ligands found: 123
No: Ligand ECFP6 Tc MDL keys Tc
1 NAP 1 1
2 NA0 0.881356 0.986301
3 TAP 0.872881 0.934211
4 NDO 0.840336 0.972603
5 NAD 0.811966 0.986111
6 N01 0.733871 0.958904
7 A3D 0.712 0.972603
8 NBP 0.707692 0.935065
9 NHD 0.68254 0.958904
10 NJP 0.661417 0.972973
11 NFD 0.658915 0.934211
12 NXX 0.619048 0.959459
13 DND 0.619048 0.959459
14 AMP NAD 0.606061 0.958904
15 ZID 0.605839 0.972603
16 NAQ 0.59854 0.922078
17 ATR 0.59292 0.917808
18 NAE 0.591241 0.946667
19 NDE 0.58042 0.986301
20 A22 0.571429 0.958904
21 NAJ 0.567164 0.986111
22 A2R 0.563025 0.932432
23 NDC 0.561644 0.922078
24 NA7 0.552846 0.907895
25 ODP 0.551471 0.935065
26 A2P 0.539823 0.930556
27 8ID 0.537313 0.910256
28 NPW 0.525547 0.8875
29 NZQ 0.521739 0.910256
30 CNA 0.521739 0.959459
31 NDP 0.514493 0.922078
32 PO4 PO4 A A A A PO4 0.503937 0.930556
33 1DG 0.503401 0.922078
34 DG1 0.503401 0.922078
35 TXP 0.5 0.922078
36 NMN AMP PO4 0.492958 0.921053
37 XNP 0.492958 0.875
38 25L 0.492308 0.958904
39 25A 0.492063 0.972222
40 NMN 0.486726 0.888889
41 NGD 0.485714 0.935065
42 9JJ 0.481707 0.8875
43 2AM 0.477876 0.891892
44 ADP 0.458333 0.945205
45 PAP 0.451613 0.931507
46 A2D 0.445378 0.945205
47 AN2 0.442623 0.932432
48 7L1 0.441558 0.777778
49 ADP PO3 0.44 0.944444
50 SAP 0.44 0.896104
51 AGS 0.44 0.896104
52 M33 0.439024 0.906667
53 AR6 AR6 0.438849 0.945205
54 BA3 0.438017 0.945205
55 OAD 0.43609 0.92
56 ADP BMA 0.43609 0.92
57 DQV 0.435714 0.958904
58 HEJ 0.435484 0.945205
59 ATP 0.435484 0.945205
60 OOB 0.435115 0.958904
61 B4P 0.434426 0.945205
62 AP5 0.434426 0.945205
63 GAP 0.433071 0.92
64 0WD 0.432432 0.922078
65 2A5 0.432 0.87013
66 5FA 0.432 0.945205
67 AQP 0.432 0.945205
68 AT4 0.430894 0.907895
69 00A 0.428571 0.909091
70 DAL AMP 0.427481 0.932432
71 CA0 0.427419 0.92
72 ADP ALF 0.426357 0.871795
73 ALF ADP 0.426357 0.871795
74 9X8 0.425373 0.871795
75 ACP 0.424 0.92
76 NAJ PZO 0.423841 0.897436
77 9SN 0.423358 0.897436
78 ADP VO4 0.423077 0.932432
79 VO4 ADP 0.423077 0.932432
80 WAQ 0.422222 0.884615
81 V3L 0.421875 0.945205
82 ACQ 0.421875 0.92
83 ADQ 0.421053 0.92
84 AR6 0.420635 0.918919
85 APR 0.420635 0.918919
86 ATP A A A 0.42029 0.958333
87 CO7 0.419753 0.786517
88 3OD 0.419118 0.92
89 1ZZ 0.419118 0.841463
90 DLL 0.41791 0.958904
91 AD9 0.417323 0.92
92 NAX 0.416667 0.875
93 OVE 0.416667 0.857143
94 MYR AMP 0.416058 0.841463
95 AV2 0.415385 0.868421
96 A3P 0.414634 0.944444
97 NNR 0.414414 0.72973
98 OMR 0.413793 0.831325
99 6YZ 0.412214 0.92
100 ANP 0.410853 0.92
101 A1R 0.410448 0.860759
102 ABM 0.409836 0.893333
103 A 0.408333 0.944444
104 AMP 0.408333 0.944444
105 SON 0.408 0.933333
106 PPS 0.407692 0.829268
107 5AL 0.407692 0.932432
108 NAI 0.406897 0.909091
109 7D3 0.406504 0.857143
110 ADX 0.404762 0.829268
111 ATF 0.40458 0.907895
112 3UK 0.404412 0.945946
113 TYR AMP 0.404255 0.921053
114 AMP DBH 0.404255 0.894737
115 139 0.402685 0.875
116 50T 0.401575 0.906667
117 SRP 0.401515 0.907895
118 A A 0.40146 0.972222
119 B5V 0.40146 0.933333
120 A3R 0.4 0.860759
121 3AM 0.4 0.90411
122 B5M 0.4 0.921053
123 FA5 0.4 0.933333
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1E7S; Ligand: NAP; Similar sites found with APoc: 741
This union binding pocket(no: 1) in the query (biounit: 1e7s.bio1) has 33 residues
No: Leader PDB Ligand Sequence Similarity
1 1Z0N BCD None
2 4YEF 4CQ None
3 1FWV SGA MAG FUC None
4 1SQL GUN None
5 4J7U YTZ 1.04167
6 4J7U NAP 1.04167
7 1Z6Z NAP 1.06383
8 2HK9 ATR 1.09091
9 2HK9 NAP 1.09091
10 2BKA NDP 1.23967
11 6A3J NAI 1.24611
12 6A3J SOE 1.24611
13 4OHU 2TK 1.38408
14 4OHU NAD 1.38408
15 4RDH AMP 1.38889
16 4D79 ATP 1.44928
17 3OIG NAD 1.50376
18 3V1Y NAD 1.55763
19 3GFB NAD 1.55763
20 1YS4 NAP 1.55763
21 4Z0H NAD 1.55763
22 3S5W NAP 1.55763
23 2NAD NAD 1.55763
24 1U25 IHS 1.55763
25 3WBF NAP 1.63934
26 1W73 NAP 1.65563
27 1W8D NAP 1.65563
28 4NBT NAD 1.66667
29 5N6C NAD 1.66667
30 4Q9N NAI 1.67785
31 2PV7 NAD 1.67785
32 3B1F NAD 1.72414
33 3H4V DVP 1.73611
34 3H4V NAP 1.73611
35 1G0N PHH 1.76678
36 1G0N NDP 1.76678
37 1O5O U5P 1.80995
38 3EVG SAH 1.81818
39 5Y77 FAD 1.86916
40 3NJ4 AFX 1.86916
41 3NJ4 NAD 1.86916
42 5Z20 NAI 1.86916
43 5M67 3D1 1.86916
44 1DLJ UGA 1.86916
45 1DLJ NAI 1.86916
46 5M67 ADE 1.86916
47 5M67 NAD 1.86916
48 1NJJ GET 1.86916
49 5JAQ NAI 1.86916
50 1VRP IOM 1.86916
51 4ZNO SUC 1.86916
52 1RJW ETF 1.86916
53 5XHA FRU 1.86916
54 5GSN FAD 1.86916
55 5GSN NAP 1.86916
56 5GSN MMZ 1.86916
57 1H5Q NAP 1.88679
58 3OA2 NAD 1.88679
59 5TH5 MET 1.90114
60 2WYV NAD 1.91571
61 5YSS NAD 1.95312
62 4GN8 ASO 2.00669
63 5T2U NAP 2.01613
64 1HDR NAD 2.04918
65 2HMT NAI 2.08333
66 1WMA AB3 2.17391
67 1WMA NDP 2.17391
68 1Y1P NMN AMP PO4 2.18069
69 3B20 NAD 2.18069
70 5A1T NAI 2.18069
71 2D2I NAP 2.18069
72 1RM4 NDP 2.18069
73 5MDH NAD 2.18069
74 3B1J NAD 2.18069
75 5A1T OXM 2.18069
76 3OJO NAD 2.18069
77 1SC6 NAD 2.18069
78 5MZI FAD 2.18069
79 5MZI FYK 2.18069
80 1DJN ADP 2.18069
81 5T96 79J 2.18069
82 1YKJ PHB 2.18069
83 1YKJ FAD 2.18069
84 4MDH NAD 2.18069
85 5UAO FAD 2.18069
86 6ER9 FAD 2.18069
87 1SAY PYR 2.18069
88 4DPL NAP 2.18069
89 6ER9 NAP 2.18069
90 5U8U FAD 2.18069
91 3T31 DCQ 2.18069
92 3T31 FAD 2.18069
93 5MIT NAP 2.18069
94 5MIT FAD 2.18069
95 1O0S NAI 2.18069
96 3IHG FAD 2.18069
97 1GQ2 NAP 2.18069
98 5TOW ADN 2.18069
99 5TOW NAI 2.18069
100 1ZH8 NAP 2.18069
101 4O0L NDP 2.18182
102 1NYT NAP 2.21402
103 4UP3 NDP 2.2293
104 1NVM NAD 2.24359
105 5X20 NAD 2.24359
106 5JBX MLI 2.29885
107 3OID NDP 2.32558
108 3RJ5 NAD 2.3622
109 4QED NAP 2.41935
110 1UZN NAP 2.42915
111 1N5D NDP 2.43056
112 5Z2L NDP 2.44898
113 1UAY ADN 2.47934
114 4TQG NDP 2.49221
115 3A06 NDP 2.49221
116 1PL6 NAD 2.49221
117 1V35 NAI 2.49221
118 1EBF NAD 2.49221
119 2O1V ADP 2.49221
120 2R2N KYN 2.49221
121 1BW9 NAD 2.49221
122 2ZJ1 NAD 2.49221
123 2ZJ1 ARJ 2.49221
124 4PLG OXM 2.49221
125 4PLG NAI 2.49221
126 1C1X NAD 2.49221
127 3GMB FAD 2.49221
128 3H5N ATP 2.49221
129 2WGH DTP 2.49221
130 3A06 FOM 2.49221
131 4E5N NAD 2.49221
132 1NVT NAP 2.49221
133 5EIN NAP 2.49221
134 1V59 NAD 2.49221
135 1PL6 572 2.49221
136 4L8V NAP 2.49221
137 4W6Z 8ID 2.49221
138 1BXG NAD 2.49221
139 4CNK FAD 2.49221
140 1A5Z NAD 2.50784
141 5U5N NAD 2.50896
142 4K26 NDP 2.53623
143 4K26 SFF 2.53623
144 1KYQ NAD 2.55474
145 1AE1 NAP 2.5641
146 3O9Z AKG 2.5641
147 3O9Z NAD 2.5641
148 2Q0L NAP 2.57235
149 4D3F NAP 2.58065
150 2CUL FAD 2.58621
151 4XDA RIB 2.589
152 1HYH NAD 2.589
153 3QWI NAP 2.59259
154 3QWI CUE 2.59259
155 1IY8 NAD 2.62172
156 1YJQ NAP 2.64026
157 5KUT GDP 2.6455
158 1I36 NAP 2.65152
159 3OJF NDP 2.72374
160 3OJF IMJ 2.72374
161 5OVK NDP 2.73438
162 3WV8 ATP 2.75229
163 5F5N NAD 2.76817
164 3ORF NAD 2.78884
165 5G4L NDP 2.7972
166 5Z21 NAI 2.80374
167 2A92 NAI 2.80374
168 1Q0H NDP 2.80374
169 1Q0H FOM 2.80374
170 5HXI FAD 2.80374
171 5KOX FAD 2.80374
172 5KOX RFP 2.80374
173 5HXI 5HN 2.80374
174 3UCL NAP 2.80374
175 3UCL CYH 2.80374
176 3UCL FAD 2.80374
177 4YKG NAD 2.80374
178 4B7X NAP 2.80374
179 5NA1 FAD 2.80374
180 2QA1 FAD 2.80374
181 1D1T NAD 2.80374
182 4D42 NAP 2.83688
183 4D42 W0I 2.83688
184 1XKQ NDP 2.85714
185 2BD0 NAP 2.86885
186 1EDO NAP 2.86885
187 3LN9 FLC 2.8777
188 1TZD ADP 2.90909
189 4MJ0 BGC SIA SIA GAL 2.90909
190 4MJ0 SIA SIA GAL 2.90909
191 4MJ0 SIA SIA 2.90909
192 5O42 NAD 2.91971
193 5O42 BGC 2.91971
194 5O42 9JW 2.91971
195 5CG1 NAD BBN 2.95082
196 1YXM ADE 2.9703
197 1SNY NAP 2.99625
198 2AG8 NAP 3.04183
199 5U5G NAP 3.05085
200 1GEE NAD 3.06513
201 1E3W NAD 3.06513
202 1E6W NAD 3.07692
203 3H8V ATP 3.08219
204 4PIV NDP 3.11526
205 1ELI PYC 3.11526
206 3ICS ADP 3.11526
207 1F8G NAD 3.11526
208 3ICT ADP 3.11526
209 3BAZ NAP 3.11526
210 1J0X NAD 3.11526
211 3FSY SCA 3.11526
212 3OND ADN 3.11526
213 3OND NAD 3.11526
214 4OKD GLC GLC GLC 3.11526
215 1U1I NAD 3.11526
216 5I34 GDP 3.11526
217 1L7E NAI 3.11526
218 4C2G ALA ALA ALA ALA 3.11526
219 2E5V FAD 3.11526
220 4XZ3 ACP 3.11526
221 5FJN BE2 3.11526
222 1Z82 NDP 3.11526
223 5FJN FAD 3.11526
224 5J3Z 6FQ 3.125
225 2QZZ NAP 3.14465
226 2QZZ EMF 3.14465
227 3O26 NDP 3.21543
228 2BGM NAJ 3.23741
229 2JAH NDP 3.23887
230 2JAP NDP 3.23887
231 3HAD NAD 3.24675
232 1XHL NDP 3.367
233 1ZL9 GSH 3.38164
234 3QV1 NAD 3.42679
235 5XWV NDP 3.42679
236 5XWV 8H6 3.42679
237 6C4T NA7 3.42679
238 1V6A TRE 3.42679
239 5AOV NAP 3.42679
240 1E5Q NDP 3.42679
241 2DFV NAD 3.42679
242 2JC9 ADN 3.42679
243 2J5V PCA 3.42679
244 3H9E NAD 3.42679
245 1KJ8 GAR 3.42679
246 3UOY FAD 3.42679
247 3UOY NAP 3.42679
248 1X87 NAD 3.42679
249 5NMX NAP 3.42679
250 5MQ6 NDP 3.42679
251 6C4M NAP 3.42679
252 6FDF SAH 3.42679
253 2GEK GDP 3.42679
254 2IXB A2G 3.42679
255 2IXB NAD 3.42679
256 6GAR FAD 3.42679
257 1QG6 NAD 3.44828
258 1QG6 TCL 3.44828
259 1X1T NAD 3.46154
260 3A4V PYR 3.47003
261 3A4V NAD 3.47003
262 3A28 NAD 3.48837
263 3K05 SEP GLN GLU TYR NH2 3.5
264 3VPH NAD 3.54839
265 3VPH OXM 3.54839
266 2GL0 ADN 3.59281
267 2EXX NAP 3.59477
268 2EWM NAD 3.61446
269 5X9D 80F 3.61842
270 5I7S NAD 3.62319
271 5I7S E9P 3.62319
272 5JE8 NAD 3.64238
273 5OVL NAP 3.66667
274 1VI2 NAD 3.66667
275 6F9Q NAD 3.67647
276 1PR9 NAP 3.68852
277 3D3W NAP 3.68852
278 5DF1 58X 3.73832
279 5DF1 NAP 3.73832
280 1I2B UPG 3.73832
281 1I2B USQ 3.73832
282 1I2B NAD 3.73832
283 5ZI2 ADP 3.73832
284 2CDU ADP 3.73832
285 5ZI2 NAD 3.73832
286 2GZ3 NAP 3.73832
287 5U7W ADE 3.73832
288 4J36 FAD 3.73832
289 4J36 1HR 3.73832
290 3ULK NDP 3.73832
291 1X14 NAD 3.73832
292 1V8B NAD 3.73832
293 1CF2 NAP 3.73832
294 6AIN FAD 3.73832
295 3GD4 NAD 3.73832
296 6A0S NDP 3.73832
297 6A0S HSE 3.73832
298 4MOP 2H5 3.73832
299 1H2B NAJ 3.73832
300 1VL8 NAP 3.74532
301 1NPD NAD 3.81944
302 5B4T 3HR 3.84615
303 5B4T NAD 3.84615
304 3TN7 NJP 3.89105
305 5EJ2 NAD 3.8961
306 3ICC NAP 3.92157
307 4FN4 NAD 3.93701
308 2F1K NAP 3.94265
309 4OOE FOM 3.9604
310 4OOE NDP 3.9604
311 4FC7 NAP 3.97112
312 4FC7 COA 3.97112
313 4YAC NAI 4.0404
314 5THQ NDP 4.04412
315 5MSO NAP 4.04984
316 1RKX NAD 4.04984
317 3L9W AMP 4.04984
318 3I6I NDP 4.04984
319 2VYN NAD 4.04984
320 1CER NAD 4.04984
321 5UR0 NAD 4.04984
322 1GAD NAD 4.04984
323 1DSS NAD 4.04984
324 1CDO NAD 4.04984
325 1C0I BE2 4.04984
326 1C0I FAD 4.04984
327 4GKV NAD 4.04984
328 4M26 AKG 4.04984
329 6FRN FMN 4.04984
330 1GZ6 NAI 4.07523
331 3UEC ALA ARG TPO LYS 4.10959
332 4O1M NAD 4.12698
333 4XDY NAI 4.14201
334 4YAG NAI 4.15225
335 5E9W SAH 4.16667
336 5E8J SAH 4.16667
337 6MDE MEV 4.29043
338 2RH4 EMO 4.33213
339 1LDM NAD 4.36137
340 4BVA NDP 4.36137
341 4TXI FAD 4.36137
342 4K5S PM0 4.36137
343 2CVQ NDP 4.36137
344 3OZ2 FAD 4.36137
345 4K5S FAD 4.36137
346 5DN9 NAD 4.36137
347 5UAV NDP 4.36137
348 3LZW NAP 4.36137
349 3LZW FAD 4.36137
350 1LLU NAD 4.36137
351 2BRY FAD 4.36137
352 1PN0 IPH 4.36137
353 1PN0 FAD 4.36137
354 5UAV TFB 4.36137
355 1DRV A3D 4.3956
356 1XSE NDP 4.40678
357 2VOH CIT 4.4586
358 2AG5 NAD 4.47154
359 3RFV NAI 4.49438
360 3RFV 15L 4.49438
361 6EV2 BGC 4.60829
362 4JK3 NAD 4.6332
363 1XG5 NAP 4.6595
364 2DC1 NAD 4.66102
365 1WVG APR 4.6729
366 5K4W NAI 4.6729
367 5K4W THR 4.6729
368 1ZBQ NAD 4.6729
369 2B4R NAD 4.6729
370 2B4R AES 4.6729
371 1TB4 PEJ 4.6729
372 3AB1 FAD 4.6729
373 4XYB NDP 4.6729
374 2Z9I GLY ALA THR VAL 4.6729
375 2O4C NAD 4.6729
376 5EOW FAD 4.69136
377 2WA2 SAM 4.71014
378 2WSB NAD 4.72441
379 5HVJ ANP 4.7619
380 2DBZ NAP 4.79042
381 5FEU NAP 4.811
382 5XVH NAP 4.90196
383 4OSP NAP 4.94297
384 4J1Q NDP 4.98442
385 3V1U NAD 4.98442
386 5LD5 NAD 4.98442
387 3C1O NAP 4.98442
388 1TI7 NAP 4.98442
389 2VUT NAD 4.98442
390 1H9A NAP 4.98442
391 2Y6Q FAD 4.98442
392 2Y6Q I7T 4.98442
393 3E1T FAD 4.98442
394 1KOL NAD 4.98442
395 5OC1 FAD 4.98442
396 6GAS FAD 4.98442
397 3TWO NDP 4.98442
398 1E3I CXF 4.98442
399 1O94 ADP 5
400 4J4H NAI 5.01931
401 4J4H 1J1 5.01931
402 5V6F MAN BMA MAN 5.07246
403 4YCA NDP 5.10204
404 1HYE NAP 5.11182
405 1J5P NAD 5.13834
406 4OM8 NAD 5.17799
407 1JAY NAP 5.18868
408 4URF NAD 5.24194
409 2GDZ NAD 5.24345
410 3GEG NAD 5.26316
411 5L4L NAP 5.26316
412 5L4L 7OX 5.26316
413 5Z2F NAP 5.28302
414 2OFW ADX 5.28846
415 3ABI NAD 5.29595
416 1N7G GDR 5.29595
417 4EUE NAI 5.29595
418 1N7G NDP 5.29595
419 1B8U NAD 5.29595
420 6BII NAP 5.29595
421 3KB6 NAD 5.29595
422 1RM0 D6P 5.29595
423 1RM0 NAI 5.29595
424 5EVY FAD 5.29595
425 4AP3 FAD 5.29595
426 4AP3 NAP 5.29595
427 1GPE FAD 5.29595
428 2D7I UDP 5.29595
429 1OMO NAD 5.29595
430 4G2R H1L 5.29595
431 5JCM NAD 5.29595
432 5JCM ISD 5.29595
433 2VHW NAI 5.29595
434 5EPO NAP 5.34351
435 3G2O SAM 5.35117
436 1TDF NAP 5.37975
437 3GGO NAI 5.41401
438 3GGO ENO 5.41401
439 2B4Q NAP 5.43478
440 4JP3 CIT 5.43933
441 4NBW NAD 5.44747
442 5FFF NAP 5.44747
443 5FFF 5XC 5.44747
444 5KKA 6V0 5.44872
445 4ZA2 NAD 5.5336
446 1WP4 NDP 5.53633
447 3SJ7 NDP 5.55556
448 4Y9D NAI 5.57377
449 4R1S NAP 5.60748
450 5Y1G NAD 5.60748
451 5Y1G AKB 5.60748
452 6EL3 NAP 5.60748
453 5LY1 PPI 5.60748
454 3WGT FAD 5.60748
455 3G5S FAD 5.60748
456 6FP4 E1T 5.60748
457 3WGT QSC 5.60748
458 4E13 NAD 5.65371
459 5OJL TXP 5.7047
460 2AE2 PTO 5.76923
461 2AE2 NAP 5.76923
462 1LC3 NAD 5.78231
463 3AFN NAP 5.81395
464 1JA9 NDP 5.83942
465 5FII PHE 5.88235
466 1HDC CBO 5.90551
467 3HB5 NAP 5.919
468 2I3G NAP 5.919
469 5JDA AMP 5.919
470 6C4N NAP 5.919
471 3QVP FAD 5.919
472 6FHO FAD 5.919
473 1LVL NAD 5.919
474 2NU8 COA 5.919
475 2JHF NAD 5.919
476 5K0A FAD 5.919
477 4JDR FAD 5.919
478 4ITU NAI 5.94796
479 4ITU 1HS 5.94796
480 4NBU NAI 6
481 2CFC NAD 6
482 2G5C NAD 6.04982
483 3C3D FO1 6.10932
484 1C3V NDP 6.12245
485 3O7W SAM 6.12245
486 3KVY R2B 6.14887
487 2ZAT NAP 6.15385
488 2V6G NAP 6.23053
489 6CEP NAD 6.23053
490 3ISN EDM 6.23053
491 6CEP OXM 6.23053
492 4ZVV NAD 6.23053
493 4ZVV GN0 6.23053
494 1T26 NAI 6.23053
495 1T26 GBD 6.23053
496 2FZW NAD 6.23053
497 4KP7 NAP 6.23053
498 4KP7 1UQ 6.23053
499 1UWK NAD 6.23053
500 1UWK URO 6.23053
501 1PS9 NAP 6.23053
502 1F06 NDP 6.25
503 1W6U NAP 6.29139
504 3CH6 NAP 6.29371
505 3CH6 311 6.29371
506 3AY6 NAI 6.3197
507 3AY6 BGC 6.3197
508 4YSX FAD 6.41026
509 1YQC GLV 6.47059
510 2VT3 ATP 6.51163
511 3CMC NAD 6.54206
512 1WDK NAD 6.54206
513 2UXR ICT 6.54206
514 5TUF TDC 6.54206
515 5TUF FAD 6.54206
516 4D04 NAP 6.54206
517 4D04 FAD 6.54206
518 5JWC FAD 6.54206
519 5X68 FAD 6.54206
520 1A27 NAP 6.57439
521 3E3U NVC 6.59898
522 4RF2 NAP 6.61765
523 1P77 ATR 6.61765
524 2UYQ SAM 6.77419
525 5OOH 9ZZ 6.79612
526 5OOH NAP 6.79612
527 2DTX BMA 6.81818
528 4XB2 NDP 6.85358
529 9LDT NAD 6.85358
530 9LDB NAD 6.85358
531 4XB2 HSE 6.85358
532 4PLT NAI 6.85358
533 4PLT OXM 6.85358
534 1TKU 5RP 6.86275
535 1NFQ NAI 6.92308
536 5O98 NAP 6.94006
537 6AA8 NAD 6.95364
538 5T9F TYR 7.01107
539 5T9E NAP 7.01107
540 5T9F NAP 7.01107
541 1HDG NAD 7.16511
542 4XQC 13D 7.16511
543 3K5I AIR 7.16511
544 1MV8 NAD 7.16511
545 4RSL FAD 7.16511
546 4JBI NDP 7.16511
547 5BRT CH9 7.16511
548 5BRT FAD 7.16511
549 4XQC NAD 7.16511
550 1LDN NAD 7.27848
551 1JNR FAD 7.33333
552 5IN4 6CK 7.47664
553 5IN4 GDP 7.47664
554 5IN4 NAP 7.47664
555 1MUU NAD 7.47664
556 1LTH NAD 7.52351
557 3SJU NDP 7.52688
558 1PZG A3D 7.55287
559 5YEC ATP 7.56302
560 1ZK4 AC0 7.56972
561 1ZK4 NAP 7.56972
562 1O5I NAD 7.63052
563 3RKR NAP 7.63359
564 2X6T NAP 7.78816
565 4RQU NAD 7.78816
566 2RGJ FAD 7.78816
567 2Q2V NAD 7.84314
568 5OCM NAP 7.90378
569 1GUZ NAD 8.06452
570 3L4S NAD 8.09969
571 3L4S 3PG 8.09969
572 4OPC PGT 8.09969
573 4OPC FDA 8.09969
574 1J49 NAD 8.09969
575 5WQP NAP 8.11966
576 5WQP NCA 8.11966
577 1UPR 4IP 8.13008
578 1MXH DHF 8.33333
579 1MXH NAP 8.33333
580 1GV0 NAD 8.3871
581 3WXB NDP 8.41121
582 2YVJ NAI 8.41121
583 1KEV NDP 8.41121
584 4X9M FAD 8.72274
585 1EZ4 NAD 8.80503
586 1Q7B NAP 9.01639
587 1SOW NAD 9.03427
588 3CIF NAD 9.03427
589 3CIF G3H 9.03427
590 4ZU3 4SD 9.2511
591 6CI9 NAP 9.26641
592 1LSS NAD 9.28571
593 1PJS NAD 9.34579
594 5JY6 NAD 9.34579
595 5GWT SIN 9.35252
596 5GWT NAD 9.35252
597 1GEG NAD 9.375
598 5AYV NAP 9.38511
599 1BDB NAD 9.38628
600 2HJR APR 9.45122
601 4KWI NAP 9.5057
602 4KWI 1TJ 9.5057
603 2XVM SAH 9.54774
604 3ZV6 4HB 9.60854
605 3ZV6 NAD 9.60854
606 5N2I NAP 9.91379
607 3U4C NDP 9.96441
608 5L95 AMP 10
609 1UXG NAD 10.0324
610 1UXG FUM 10.0324
611 5H81 NAP 10.2804
612 3NUG NAD 10.5263
613 2PD4 DCN 10.5455
614 2PD4 NAD 10.5455
615 6DW2 HD4 10.5485
616 5ZZ6 ADP 10.5769
617 5ZZ6 NAD 10.5769
618 4U7W NDP 10.5919
619 2FR1 NDP 10.5919
620 5CAE COA 10.5919
621 1KSK URA 10.6838
622 1D7O TCL 10.7744
623 1D7O NAD 10.7744
624 1YKF NAP 10.9034
625 3QDW A2G 11.1888
626 5NUF NAD 11.215
627 5NUE NAD 11.215
628 2DT5 NAD 11.3744
629 1VM6 NAD 11.4035
630 4CQM NAP 11.4754
631 5ZEC NAP 11.5265
632 4HXY NDP 11.5265
633 4ZGS NAD 11.5265
634 2FN1 PYR 11.5265
635 2DKN NAI 11.7647
636 1NM5 NAD 11.8227
637 1ZEM NAD 11.8321
638 4R5M NAP 11.838
639 4R5M 4NO 11.838
640 5WUW NAP 11.8467
641 2JL1 NAP 11.8467
642 4UP5 94W 12.1212
643 5GT9 NAP 12.1673
644 2GMH FAD 12.4611
645 1U7T NAD 12.6437
646 1U7T TDT 12.6437
647 1FK8 NAD 12.8405
648 1O6Z NAD 12.8713
649 4PVD NDP 13.3956
650 1OAA OAA 13.5135
651 3JQA NAP 13.5417
652 3BMO NAP 13.5417
653 3BMQ NAP 13.5417
654 4CM4 NAP 13.5417
655 3JQF NAP 13.5417
656 5JDI NAP 13.5417
657 4CM8 NAP 13.5417
658 3JQG NAP 13.5417
659 3JQ9 NAP 13.5417
660 5JDC NAP 13.5417
661 4CMI NAP 13.5417
662 5K6A NAP 13.5417
663 5JCJ NAP 13.5417
664 3JQ8 NAP 13.5417
665 4CM9 NAP 13.5417
666 4CLO NAP 13.5417
667 3BMN NAP 13.5417
668 4CME NAP 13.5417
669 4CLR NAP 13.5417
670 3JQB NAP 13.5417
671 3JQ7 NAP 13.5417
672 3O03 NAP 13.7457
673 2OOR NAD 13.7931
674 2OFD NGA 14.0845
675 2WD7 NAP 14.5522
676 2VZ0 NAP 14.5522
677 2VZ0 D64 14.5522
678 5OJI NAP 14.6154
679 5OJI ISN 14.6154
680 1NNU NAD 15
681 1NNU TCT 15
682 2C29 NAP 16.1994
683 2C29 DQH 16.1994
684 5BJX NAD 16.1994
685 5BJX UDP 16.1994
686 4CJX NAP 16.9279
687 1LUA NAP 17.0732
688 3VZS NAP 17.1206
689 3VZS CAA 17.1206
690 4G5H NAP 17.134
691 4G5H UD7 17.134
692 2GN4 UD1 17.757
693 2GN4 NDP 17.757
694 1Q8A HCS 18.0685
695 5MLR NAP 18.6916
696 5MLR GRQ 18.6916
697 4YEE 4CQ 18.8889
698 5L53 NAP 19.0031
699 2GCG NDP 19.6262
700 1Q3P GLU ALA GLN THR ARG LEU 20.1835
701 1RPN NDP 20.2985
702 5EES NAP 20.6478
703 3LU1 NAD 20.8723
704 3WMX NAD 20.8723
705 5L4S 6KX 21.1838
706 5L4S NAP 21.1838
707 2WG9 OCA 23.0769
708 1VL0 NAI 25.6849
709 2PZM NAD 27.1028
710 2PZM UDP 27.1028
711 2Q46 NAP 27.2727
712 1SB8 NAD 29.9065
713 1SB8 UD2 29.9065
714 1EQ2 NAP 30
715 1R6D NAD 32.7103
716 1R6D DAU 32.7103
717 6DNT NAD 34.2679
718 6DNT EPZ 34.2679
719 1GY8 NAD 35.514
720 1EK6 UPG 37.3832
721 1EK6 NAI 37.3832
722 1Z45 NAD 38.0062
723 5Z75 NAD 38.3178
724 2PK3 A2R 38.3178
725 2YY7 NAD 39.7436
726 1UDB UFG 39.8754
727 1UDB NAD 39.8754
728 2Q1W NAD 40.1869
729 4GLL NAD 41.1215
730 1OC2 NAD 42.0561
731 1OC2 TDX 42.0561
732 6BWL NAD 42.9907
733 3KO8 NAD 43.9103
734 2Q1S NAI 43.9252
735 2C5A NAD 44.5483
736 2C5A GDC 44.5483
737 1KEW NAD 45.4829
738 1KEW TYD 45.4829
739 1BXK NAD 45.7944
740 4ZRN NAD 46.7949
741 4ZRN UPG 46.7949
Pocket No.: 2; Query (leader) PDB : 1E7S; Ligand: NAP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 1e7s.bio1) has 33 residues
No: Leader PDB Ligand Sequence Similarity
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