-->
Receptor
PDB id Resolution Class Description Source Keywords
1EHI 2.38 Å EC: 6.3.2.4 D-ALANINE:D-LACTATE LIGASE (LMDDL2) OF VANCOMYCIN-RESISTANT LEUCONOSTOC MESENTEROIDES LEUCONOSTOC MESENTEROIDES ATP-BINDING. GRASP MOTIF FOR ATP. LIGASE
Ref.: ENZYMES OF VANCOMYCIN RESISTANCE: THE STRUCTURE OF D-ALANINE-D-LACTATE LIGASE OF NATURALLY RESISTANT LEUCONOSTOC MESENTEROIDES. STRUCTURE FOLD.DES. V. 8 463 2000
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ADP A:781;
Valid;
none;
submit data
427.201 C10 H15 N5 O10 P2 c1nc(...
MG A:783;
A:784;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
PHY A:782;
Valid;
none;
submit data
275.133 C6 H15 N O7 P2 C[C@@...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1EHI 2.38 Å EC: 6.3.2.4 D-ALANINE:D-LACTATE LIGASE (LMDDL2) OF VANCOMYCIN-RESISTANT LEUCONOSTOC MESENTEROIDES LEUCONOSTOC MESENTEROIDES ATP-BINDING. GRASP MOTIF FOR ATP. LIGASE
Ref.: ENZYMES OF VANCOMYCIN RESISTANCE: THE STRUCTURE OF D-ALANINE-D-LACTATE LIGASE OF NATURALLY RESISTANT LEUCONOSTOC MESENTEROIDES. STRUCTURE FOLD.DES. V. 8 463 2000
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 5 families.
1 1EHI - PHY C6 H15 N O7 P2 C[C@@H](C[....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 1EHI - PHY C6 H15 N O7 P2 C[C@@H](C[....
50% Homology Family (12)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 2I80 Ki = 4 uM G1L C12 H13 Cl F3 N O CC(C)(CCl)....
2 2I8C - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
3 3N8D - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
4 5BPF - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
5 5C1O - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
6 5BPH - AMP C10 H14 N5 O7 P c1nc(c2c(n....
7 5C1P - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
8 1EHI - PHY C6 H15 N O7 P2 C[C@@H](C[....
9 1IOV - POB C6 H15 N O8 P2 CC[C@H](C(....
10 2DLN - PHY C6 H15 N O7 P2 C[C@@H](C[....
11 4L1K - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
12 4ME6 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ADP; Similar ligands found: 452
No: Ligand ECFP6 Tc MDL keys Tc
1 ADP 1 1
2 HEJ 0.9 1
3 ATP 0.9 1
4 A2D 0.895522 0.971831
5 5FA 0.887324 1
6 AQP 0.887324 1
7 AP5 0.884058 0.971831
8 B4P 0.884058 0.971831
9 BA3 0.869565 0.971831
10 AN2 0.84507 0.985915
11 AT4 0.84507 0.958904
12 M33 0.833333 0.958333
13 ACQ 0.826667 0.972222
14 A 0.823529 0.971429
15 AMP 0.823529 0.971429
16 ACP 0.821918 0.972222
17 6YZ 0.818182 0.972222
18 APR 0.810811 0.971831
19 AR6 0.810811 0.971831
20 ANP 0.802632 0.972222
21 SAP 0.8 0.945946
22 AGS 0.8 0.945946
23 AD9 0.8 0.972222
24 ADX 0.783784 0.873418
25 CA0 0.783784 0.945205
26 TAT 0.779221 0.958904
27 T99 0.779221 0.958904
28 50T 0.773333 0.958333
29 ABM 0.763889 0.917808
30 APC 0.763158 0.958904
31 PRX 0.763158 0.893333
32 ATF 0.759494 0.958904
33 A22 0.753086 0.985915
34 AP2 0.743243 0.958904
35 A12 0.743243 0.958904
36 SRA 0.736111 0.918919
37 ADQ 0.73494 0.945205
38 25L 0.732558 0.985915
39 5AL 0.725 0.931507
40 2A5 0.717949 0.918919
41 A1R 0.714286 0.907895
42 AU1 0.714286 0.972222
43 A3R 0.714286 0.907895
44 ATR 0.708861 0.971429
45 ADP PO3 0.708861 0.943662
46 PAP 0.708861 0.985714
47 SRP 0.707317 0.906667
48 7D3 0.706667 0.905405
49 25A 0.702381 0.971831
50 9X8 0.697674 0.92
51 OAD 0.697674 0.945205
52 RBY 0.6875 0.932432
53 ADV 0.6875 0.932432
54 00A 0.686047 0.883117
55 OOB 0.682353 0.931507
56 5SV 0.682353 0.848101
57 8QN 0.682353 0.931507
58 3OD 0.681818 0.945205
59 BIS 0.681818 0.933333
60 ALF ADP 0.674699 0.87013
61 ADP ALF 0.674699 0.87013
62 AMO 0.674419 0.932432
63 4AD 0.674419 0.92
64 PAJ 0.674419 0.884615
65 GAP 0.670732 0.893333
66 MAP 0.670588 0.945946
67 AHX 0.666667 0.896104
68 VO4 ADP 0.666667 0.931507
69 DLL 0.666667 0.931507
70 ADP VO4 0.666667 0.931507
71 PTJ 0.662921 0.896104
72 3UK 0.659091 0.918919
73 SON 0.658228 0.932432
74 LMS 0.653333 0.82716
75 LAD 0.651685 0.860759
76 WAQ 0.651685 0.883117
77 B5V 0.651685 0.906667
78 PR8 0.651685 0.85
79 ITT 0.65 0.943662
80 7D4 0.65 0.905405
81 G5P 0.648936 0.921053
82 XYA 0.647059 0.84507
83 ADN 0.647059 0.84507
84 RAB 0.647059 0.84507
85 1ZZ 0.644444 0.839506
86 ME8 0.644444 0.839506
87 FYA 0.644444 0.905405
88 NB8 0.644444 0.896104
89 TXA 0.644444 0.932432
90 6AD 0.642857 0.909091
91 ADP BMA 0.640449 0.918919
92 G3A 0.638298 0.921053
93 DAL AMP 0.632184 0.905405
94 AFH 0.631579 0.884615
95 9SN 0.630435 0.871795
96 9ZA 0.625 0.907895
97 DQV 0.625 0.958333
98 9ZD 0.625 0.907895
99 GTA 0.625 0.886076
100 YAP 0.623656 0.894737
101 B5M 0.623656 0.894737
102 FA5 0.623656 0.906667
103 B5Y 0.623656 0.894737
104 UP5 0.622449 0.92
105 HFD 0.619048 0.945946
106 XAH 0.617021 0.839506
107 AV2 0.616279 0.917808
108 AOC 0.615385 0.821918
109 48N 0.612245 0.896104
110 4UV 0.610526 0.894737
111 6V0 0.606061 0.896104
112 NAI 0.606061 0.907895
113 DND 0.606061 0.932432
114 NAX 0.606061 0.873418
115 NXX 0.606061 0.932432
116 TXD 0.606061 0.907895
117 5N5 0.605634 0.819444
118 5AS 0.604938 0.77907
119 A4P 0.60396 0.843373
120 DAT 0.60241 0.905405
121 A2R 0.602273 0.985915
122 TXE 0.6 0.907895
123 OMR 0.6 0.851852
124 4UU 0.597938 0.894737
125 GA7 0.597938 0.906667
126 A A 0.597826 0.944444
127 A4D 0.597222 0.819444
128 5CD 0.597222 0.805556
129 AP0 0.594059 0.896104
130 4TC 0.594059 0.896104
131 A3P 0.592593 0.971429
132 T5A 0.592233 0.841463
133 139 0.592233 0.873418
134 7D5 0.592105 0.878378
135 ATP A A A 0.589474 0.930556
136 LAQ 0.585859 0.839506
137 MYR AMP 0.585106 0.817073
138 F2R 0.580952 0.864198
139 YLP 0.58 0.819277
140 UPA 0.578431 0.907895
141 7DD 0.578313 0.985714
142 3AM 0.576923 0.929577
143 ADJ 0.576923 0.851852
144 COD 0.575472 0.811765
145 NAD 0.575472 0.931507
146 3AT 0.574713 0.971831
147 JB6 0.574468 0.883117
148 4UW 0.574257 0.860759
149 EP4 0.573333 0.753247
150 A2P 0.573171 0.957143
151 CNA 0.571429 0.932432
152 TYM 0.568627 0.906667
153 PPS 0.568182 0.873418
154 DTA 0.565789 0.786667
155 M2T 0.565789 0.734177
156 AR6 AR6 0.565657 0.917808
157 A3D 0.564815 0.918919
158 80F 0.564815 0.841463
159 3DH 0.564103 0.773333
160 G5A 0.563218 0.77907
161 YLB 0.563107 0.819277
162 YLC 0.563107 0.839506
163 AMP DBH 0.561224 0.893333
164 TYR AMP 0.561224 0.87013
165 MTA 0.558442 0.773333
166 DTP 0.556818 0.905405
167 AHZ 0.554455 0.817073
168 NA7 0.553191 0.958904
169 IOT 0.552381 0.831325
170 ZAS 0.55 0.766234
171 7MD 0.55 0.8625
172 ARG AMP 0.55 0.829268
173 IMO 0.548781 0.929577
174 YLA 0.54717 0.819277
175 NAE 0.544643 0.894737
176 TAD 0.544554 0.884615
177 A5A 0.544444 0.807229
178 2AM 0.544304 0.943662
179 TSB 0.543478 0.819277
180 6RE 0.54321 0.759494
181 AYB 0.542056 0.809524
182 NAQ 0.539823 0.871795
183 V3L 0.539326 0.971831
184 SSA 0.538462 0.8
185 AF3 ADP 3PG 0.538462 0.8375
186 ZID 0.535088 0.918919
187 LPA AMP 0.533981 0.817073
188 52H 0.532609 0.77907
189 VMS 0.532609 0.788235
190 54H 0.532609 0.788235
191 BTX 0.53211 0.841463
192 A3N 0.53012 0.786667
193 J7C 0.53012 0.769231
194 5X8 0.528736 0.763158
195 BT5 0.527273 0.831325
196 8X1 0.526882 0.752809
197 5CA 0.526882 0.8
198 53H 0.526882 0.77907
199 ARU 0.526316 0.860759
200 EAD 0.525862 0.873418
201 RGT 0.525253 0.958904
202 OVE 0.52439 0.905405
203 S4M 0.52381 0.666667
204 7DT 0.522727 0.985714
205 GDP 0.522222 0.92
206 DDS 0.522222 0.878378
207 AVV 0.521277 0.896104
208 NDE 0.521008 0.932432
209 7MC 0.518868 0.841463
210 DSH 0.518072 0.725
211 MAO 0.517647 0.759036
212 NSS 0.515789 0.8
213 DSZ 0.515789 0.8
214 LSS 0.515789 0.761364
215 P5A 0.515464 0.744444
216 DZD 0.513514 0.884615
217 NVA LMS 0.510417 0.752809
218 9K8 0.510204 0.714286
219 12D 0.509615 0.785714
220 M24 0.508772 0.85
221 YLY 0.508772 0.809524
222 P1H 0.508333 0.851852
223 5AD 0.506849 0.746479
224 GJV 0.505882 0.75
225 LEU LMS 0.505155 0.752809
226 AMP NAD 0.504505 0.905405
227 4TA 0.504505 0.807229
228 G A A A 0.504505 0.871795
229 NAJ PZO 0.504425 0.848101
230 GSU 0.5 0.77907
231 128 0.5 0.776471
232 KAA 0.5 0.752809
233 71V 0.5 0.907895
234 A3G 0.5 0.8
235 NDC 0.5 0.871795
236 7D7 0.5 0.743243
237 N0B 0.495726 0.819277
238 NJP 0.495495 0.945946
239 ODP 0.495495 0.909091
240 2SA 0.494624 0.932432
241 6C6 0.494505 0.881579
242 SFG 0.494382 0.75
243 0WD 0.491071 0.921053
244 YSA 0.490196 0.77907
245 PO4 PO4 A A A A PO4 0.489796 0.902778
246 SAM 0.48913 0.690476
247 6IA 0.48913 0.8375
248 A7D 0.488636 0.776316
249 6FA 0.488 0.841463
250 FB0 0.487805 0.804598
251 NAJ PYZ 0.487179 0.807229
252 A5D 0.483516 0.786667
253 IDP 0.483516 0.918919
254 SA8 0.483516 0.707317
255 PGS 0.483146 0.883117
256 MHZ 0.483146 0.697674
257 DA 0.482353 0.878378
258 D5M 0.482353 0.878378
259 NEC 0.482353 0.746667
260 NIA 0.481928 0.822785
261 Y3J 0.480519 0.726027
262 8PZ 0.480392 0.8
263 FAD 0.480315 0.851852
264 FAS 0.480315 0.851852
265 FDA 0.48 0.833333
266 N6P 0.479592 0.915493
267 GGZ 0.479167 0.825
268 U A 0.478261 0.907895
269 SAH 0.478261 0.74359
270 SAI 0.478261 0.734177
271 A G 0.477876 0.883117
272 NPW 0.477477 0.886076
273 NDP 0.477477 0.921053
274 AAM 0.476744 0.971429
275 C2R 0.47561 0.90411
276 AMZ 0.47561 0.916667
277 A A A 0.474747 0.905405
278 GTP 0.473684 0.92
279 U A G G 0.473684 0.883117
280 SMM 0.473684 0.686047
281 NZQ 0.473214 0.909091
282 TXP 0.473214 0.921053
283 A3S 0.47191 0.810811
284 SFD 0.46875 0.734043
285 AIR 0.468354 0.901408
286 AAT 0.468085 0.707317
287 EEM 0.468085 0.690476
288 J7V 0.466667 0.833333
289 Z5A 0.466667 0.77907
290 7C5 0.466667 0.818182
291 62F 0.465649 0.8625
292 HDV 0.463158 0.893333
293 FAY 0.462121 0.8625
294 A3T 0.461538 0.821918
295 ETB 0.461538 0.833333
296 DCA 0.461538 0.823529
297 A6D 0.46 0.722892
298 A U 0.459459 0.87013
299 GEK 0.459184 0.7375
300 6K6 0.459184 0.930556
301 RFL 0.458647 0.821429
302 NAP 0.458333 0.945205
303 S7M 0.458333 0.690476
304 4YB 0.457944 0.761364
305 WSA 0.454545 0.788235
306 TAP 0.454545 0.907895
307 FNK 0.454545 0.804598
308 COA 0.453782 0.823529
309 0T1 0.453782 0.823529
310 101 0.453488 0.878378
311 XNP 0.452174 0.873418
312 NA0 0.45082 0.932432
313 7RP 0.448276 0.928571
314 GP3 0.446809 0.921053
315 TM1 0.446602 0.77381
316 APU 0.446429 0.894737
317 PUA 0.445378 0.884615
318 V1N 0.443396 0.917808
319 7RA 0.443182 0.957747
320 COS 0.442623 0.804598
321 AMX 0.442623 0.833333
322 30N 0.442623 0.752688
323 CAO 0.442623 0.795455
324 QQY 0.44186 0.815789
325 ACK 0.44186 0.861111
326 649 0.441441 0.744444
327 0UM 0.44 0.698795
328 NHD 0.439655 0.905405
329 CMX 0.439024 0.823529
330 SCO 0.439024 0.823529
331 GCP 0.438776 0.896104
332 8BR 0.438202 0.906667
333 GNH 0.4375 0.907895
334 8Q2 0.4375 0.772727
335 3AD 0.4375 0.805556
336 NVA 2AD 0.43617 0.759494
337 62X 0.435644 0.666667
338 FCX 0.435484 0.795455
339 ACO 0.435484 0.795455
340 FAM 0.435484 0.804598
341 9JJ 0.434783 0.8625
342 GNP 0.434343 0.896104
343 9GM 0.434343 0.896104
344 NMX 0.433071 0.76087
345 MGP 0.43299 0.884615
346 26A 0.432099 0.763158
347 HAX 0.432 0.804598
348 K15 0.431373 0.682353
349 DG1 0.430894 0.921053
350 1DG 0.430894 0.921053
351 QQX 0.430233 0.805195
352 2VA 0.430108 0.8
353 S8M 0.43 0.759494
354 2MC 0.429688 0.769231
355 6G0 0.428571 0.884615
356 P5F 0.428571 0.823529
357 FYN 0.428571 0.823529
358 3KK 0.428571 0.804598
359 A C A C 0.428571 0.848101
360 7L1 0.427419 0.795455
361 FAI 0.426966 0.916667
362 RMB 0.426966 0.873239
363 AS 0.426966 0.833333
364 1RB 0.425287 0.885714
365 CA6 0.425197 0.729167
366 SOP 0.425197 0.804598
367 OXK 0.425197 0.804598
368 MCD 0.425197 0.804598
369 COK 0.425197 0.804598
370 G1R 0.424242 0.907895
371 SXZ 0.423077 0.710843
372 CC5 0.423077 0.816901
373 F2N 0.422535 0.813953
374 EO7 0.422222 0.788235
375 ANZ 0.422018 0.8
376 1VU 0.421875 0.795455
377 CMC 0.421875 0.804598
378 CO6 0.421875 0.804598
379 ZDA 0.421053 0.864865
380 GKE 0.420561 0.884615
381 GDC 0.420561 0.884615
382 GDD 0.420561 0.884615
383 NFD 0.420168 0.883117
384 GSP 0.42 0.873418
385 D3Y 0.42 0.789474
386 MC4 0.419847 0.76087
387 3D1 0.419753 0.773333
388 3L1 0.419753 0.773333
389 FA9 0.41958 0.864198
390 5GP 0.419355 0.906667
391 G 0.419355 0.906667
392 KB1 0.419048 0.698795
393 CAJ 0.418605 0.804598
394 SCD 0.418605 0.823529
395 CMP 0.417582 0.901408
396 2BA 0.417582 0.915493
397 SO8 0.416667 0.789474
398 VRT 0.416667 0.769231
399 N01 0.416667 0.905405
400 IVC 0.415385 0.813953
401 1HE 0.415385 0.786517
402 A1S 0.415385 0.804598
403 BCO 0.415385 0.804598
404 3HC 0.415385 0.813953
405 MLC 0.415385 0.804598
406 NMN AMP PO4 0.415254 0.87013
407 2FA 0.414634 0.813333
408 MGO 0.414141 0.860759
409 3NZ 0.413462 0.782051
410 COO 0.412214 0.804598
411 MCA 0.412214 0.795455
412 YE1 0.412214 0.813953
413 CAA 0.412214 0.813953
414 GAV 0.411765 0.884615
415 PRT 0.411215 0.931507
416 JLN 0.411111 0.890411
417 P2P 0.411111 0.902778
418 ZZB 0.410256 0.77381
419 SP1 0.409091 0.842105
420 RP1 0.409091 0.842105
421 2CP 0.409091 0.795455
422 SCA 0.409091 0.804598
423 103 0.409091 0.837838
424 PAX 0.408 0.829268
425 FAD NBT 0.407143 0.75
426 COW 0.406015 0.795455
427 3CP 0.406015 0.804598
428 IRC 0.406015 0.813953
429 BYC 0.406015 0.804598
430 CA8 0.406015 0.729167
431 1GZ 0.406015 0.795455
432 COF 0.406015 0.786517
433 HGG 0.406015 0.804598
434 2KQ 0.406015 0.786517
435 G2P 0.405941 0.884615
436 SLU 0.404959 0.770115
437 U A C C 0.404959 0.858974
438 RBZ 0.404494 0.849315
439 1CZ 0.404412 0.795455
440 FAQ 0.402985 0.804598
441 BCA 0.402985 0.795455
442 4CA 0.402985 0.795455
443 MTP 0.402439 0.730769
444 8OD 0.402062 0.945205
445 CO7 0.401515 0.804598
446 GRA 0.4 0.804598
447 G2R 0.4 0.884615
448 ENQ 0.4 0.916667
449 CNV FAD 0.4 0.8
450 GMV 0.4 0.896104
451 HXC 0.4 0.786517
452 HF7 0.4 0.893333
Ligand no: 2; Ligand: PHY; Similar ligands found: 6
No: Ligand ECFP6 Tc MDL keys Tc
1 PHY 1 1
2 P0D 0.519231 0.878049
3 2D8 0.5 0.8
4 LY0 0.5 0.8
5 POB 0.446809 0.829268
6 AEP 0.413043 0.681818
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1EHI; Ligand: ADP; Similar sites found with APoc: 402
This union binding pocket(no: 1) in the query (biounit: 1ehi.bio1) has 21 residues
No: Leader PDB Ligand Sequence Similarity
1 5MJA 7O3 0.655738
2 5W4W 9WG 1.20846
3 4KBA 1QM 1.20846
4 5OKT 9XK 1.27389
5 4WB7 ATP 1.32626
6 1Y57 MPZ 1.32626
7 6AC9 ANP 1.35135
8 5H4S RAM 1.40845
9 6BXI ANP 1.5015
10 4NZN 2OU 1.51515
11 4NZN ANP 1.51515
12 3LXK MI1 1.52905
13 6CMJ F6J 1.55763
14 2F2U M77 1.59151
15 4YZC STU 1.59151
16 4EN4 GT1 1.60256
17 4EN4 ATP 1.60256
18 5JFS 6K0 1.62338
19 1ZY5 ANP 1.65016
20 2IF8 ADP 1.65289
21 3ETH ATP 1.69014
22 3G5D 1N1 1.74825
23 3PP0 03Q 1.77515
24 6FL8 ADP 1.85676
25 6FL8 TIY 1.85676
26 3IGO ANP 1.85676
27 5CKW ANP 1.85676
28 4PNI KQQ 1.85676
29 4L9I 8PR 1.85676
30 6GZD LCI 1.87166
31 4AUA 4AU 1.9544
32 1VJY 460 1.9802
33 2B9J ADP 1.983
34 2B9H ADP 1.983
35 2B9I ADP 1.983
36 2B9F ADP 1.983
37 4GJ3 0XP 1.98676
38 4WB6 ATP 2
39 3HAV ATP 2.00669
40 5JZJ AN2 2.0202
41 4CS9 AMP 2.1164
42 4XH0 ADP 2.12202
43 4OCJ NDG 2.12202
44 4UAL 3FV 2.12202
45 5AWM ANP 2.12202
46 1OPK P16 2.12202
47 3X01 AMP 2.12202
48 4WHZ 3NL 2.12202
49 5Y86 HRM 2.12202
50 3TTI KBI 2.12202
51 2RIO ADP 2.12202
52 4UHL VFV 2.12202
53 4JR7 GNP 2.13904
54 2R5T ANP 2.14477
55 3TKI S25 2.16718
56 4IZY 1J2 2.16802
57 4DFU QUE 2.17391
58 2HY0 306 2.17391
59 2Z7R STU 2.18069
60 5C4L 4XR 2.18069
61 4UX9 ANP 2.1978
62 3PTG 932 2.20386
63 2YAB AMP 2.21607
64 4P5Z Q7M 2.21607
65 3E7O 35F 2.22222
66 3VHE 42Q 2.22841
67 5VCV 1N1 2.2508
68 4L3L 5FI 2.30263
69 3MVH WFE 2.33918
70 4PZ6 GMP 2.38727
71 2JLD AG1 2.38727
72 4NM5 ADP 2.38727
73 5IM3 DTP 2.38727
74 2PYW ADP 2.38727
75 1GPE FAD 2.38727
76 4U44 3D9 2.40964
77 6F5U CQN 2.42424
78 3ZRM ZRM 2.42588
79 4LH7 1X8 2.47678
80 4AG8 AXI 2.53165
81 6C7Y ADP 2.5641
82 5JKG 6LF 2.57235
83 2WQN ADP 2.58065
84 2J7T 274 2.64901
85 1KJ8 GAR 2.65252
86 1KJ8 ATP 2.65252
87 2VPQ ANP 2.65252
88 3ORQ ADP 2.65252
89 4DC2 ADE 2.65252
90 3V8S 0HD 2.65252
91 4U98 ACP 2.65252
92 4PU5 ANP 2.65252
93 4QTB 38Z 2.65252
94 4E93 GUI 2.65252
95 4BTK DTQ 2.67062
96 4AT3 LTI 2.67559
97 3GC8 B45 2.7027
98 4N70 2HX 2.7439
99 6GQM F8H 2.7439
100 4CLI 5P8 2.75229
101 4H3Q ANP 2.76243
102 6A1G 9OL 2.77778
103 1V0O INR 2.77778
104 1S68 AMP 2.81124
105 5LI1 ANP 2.82486
106 3LXN MI1 2.83019
107 1TQP ATP 2.83688
108 1O9U ADZ 2.85714
109 1IA9 ANP 2.85714
110 5LI9 ACP 2.85714
111 3F7Z 34O 2.85714
112 3CY2 MB9 2.86624
113 4M69 ANP 2.8754
114 4CSV STI 2.90909
115 4NFN 2KC 2.91262
116 5VLQ ANP 2.91777
117 3WVR AMP 2.91777
118 4GYI ADP 2.91777
119 2WU6 DKI 2.91777
120 3DNT ATP 2.91777
121 4ONA UW1 2.91777
122 4AZW ATP 2.91777
123 3TPV ADE 2.91777
124 4WNK 453 2.91777
125 2FB3 5AD 2.94118
126 2FB3 MET 2.94118
127 2FB3 GTP 2.94118
128 4TWP AXI 2.95203
129 4YMJ 4EJ 2.96053
130 5DEY 59T 3.0303
131 4AU8 Z3R 3.04054
132 3ALN ANP 3.0581
133 5TA6 79D 3.07263
134 1UNH IXM 3.08219
135 3O0G 3O0 3.08219
136 1KW6 BPY 3.08219
137 3BP1 GUN 3.10345
138 2QX0 PH2 3.14465
139 5T8O 76Z 3.15186
140 6C0T EE4 3.17003
141 4FG8 ATP 3.1746
142 2QK4 ATP 3.18302
143 4UWH JXM 3.18302
144 3TII ANP 3.18302
145 5I35 ANP 3.18302
146 2PZI AXX 3.18302
147 1MEX RAC 3.25581
148 3FC2 IBI 3.28358
149 4H3P ANP 3.31492
150 3GGF GVD 3.32226
151 5BVE 4VG 3.3241
152 1CKN GTP 3.33333
153 1CKM GTP 3.33333
154 4I94 ANP 3.33333
155 1PHK ATP 3.3557
156 1Z2P ACP 3.39506
157 1Z2P I3S 3.39506
158 2XK9 XK9 3.41615
159 4XV1 904 3.42466
160 5DZT AMP 3.44828
161 4EUU BX7 3.44828
162 1U5R ATP 3.44828
163 6C1S EFV 3.44828
164 4CRL C1I 3.44828
165 1OUK 084 3.55191
166 6FYV 3NG 3.56083
167 3DLS ADP 3.58209
168 4GLW 0XT 3.60656
169 3SLS ANP 3.61842
170 5HCY 60D 3.62538
171 6CQF F97 3.7037
172 2HGS ADP 3.71353
173 4FL3 ANP 3.71353
174 3E5A VX6 3.73134
175 4KS7 X4Z 3.76712
176 4E1Z 0MX 3.78007
177 5USZ SKE 3.80623
178 6GWR FEW 3.80952
179 4OTH DRN 3.81232
180 2V7O DRN 3.86905
181 4R78 AMP 3.8835
182 4I6H 1C8 3.8961
183 3EKK GS2 3.90879
184 3NW7 LGV 3.90879
185 4XZ3 ACP 3.91304
186 4XYM A12 3.91304
187 6G34 5ID 3.92157
188 4OUC 5ID 3.92157
189 1IR3 ANP 3.92157
190 3BU5 ATP 3.92157
191 4NST ADP 3.9886
192 2XMY CDK 4.02685
193 3PLS ANP 4.02685
194 2R4V GSH 4.04858
195 3WV6 GAL BGC 4.05405
196 3PN1 IVH 4.08805
197 5COU ATP 4.11765
198 3DGY 2GP 4.12371
199 5HVJ ANP 4.12698
200 2R7K AMZ 4.15512
201 2R7K ACP 4.15512
202 2PVF ACP 4.19162
203 4OH4 ANP 4.2042
204 2YAK OSV 4.21053
205 5EQY 5RA 4.24403
206 4O1P ANP 4.24403
207 4A4X JUP 4.24403
208 2OO0 XAP 4.24403
209 5WO4 B7V 4.30464
210 2VN9 GVD 4.31894
211 5TDF ADP 4.32099
212 5EFQ ADP 4.32277
213 4UDK NDG 4.32277
214 2OFV 242 4.33213
215 2Q7D ANP 4.33526
216 3BZ3 YAM 4.34783
217 5M06 ADP 4.34783
218 1K3A ACP 4.34783
219 5WNL STU 4.38596
220 1GSA ADP 4.43038
221 3RI1 3RH 4.47284
222 5LVP ATP 4.50161
223 4Y0X ADP 4.50928
224 5DXT 5H5 4.50928
225 2PUL ACP 4.50928
226 5LPZ ADP 4.51807
227 3TXO 07U 4.53258
228 5A6N U7E 4.59364
229 2JDR L20 4.67836
230 2JDR GLY ARG PRO ARG THR THR SER PHE ALA GLU 4.67836
231 5LPB ADP 4.72973
232 2F57 23D 4.73186
233 6ES0 BW8 4.73186
234 3TY5 ATP 4.77454
235 3TY5 ADP 4.77454
236 3KMW ATP 4.79705
237 1JPA ANP 4.80769
238 4IX4 ADP 4.85714
239 4RDL FUC GAL NDG FUC 4.87013
240 4WNP 3RJ 4.87805
241 2WEL K88 4.89297
242 3QDY A2G GAL 4.8951
243 3UIM ANP 4.90798
244 1XJD STU 4.92754
245 3WO0 ALA 5.03979
246 3WO0 ADP 5.03979
247 3V4S ATP 5.03979
248 3V4S ADP 5.03979
249 2BMB PMM 5.03979
250 3SRV S19 5.05415
251 4F4P 0SB 5.12821
252 5EXK 5AD 5.13595
253 5X8I SQZ 5.20231
254 1OBD ATP 5.22876
255 6FYL 3NG 5.23416
256 5GZ9 ANP 5.2459
257 2IO8 ADP 5.30504
258 2CFM AMP 5.30504
259 5ZTN CUR 5.30504
260 4OAV ACP 5.30504
261 6G33 5ID 5.30973
262 4BHN BH9 5.38922
263 1XK5 TPG 5.39216
264 1BYG STU 5.39568
265 3RE4 TO1 5.42636
266 1ZTH ADP 5.42636
267 5XVG 8FX 5.46075
268 1SQL GUN 5.47945
269 4NFE BEN 5.48523
270 5C03 AGS 5.55556
271 2AGC DAO 5.55556
272 6EZ6 C5Z 5.57029
273 5C9P FUC 5.57029
274 5AE9 OKO 5.57029
275 5UIU 8CG 5.57276
276 5KO1 6UY 5.65371
277 1UPR 4IP 5.69106
278 3VPD ANP 5.69395
279 2QLU ADE 5.73248
280 2XOC ADP 5.74713
281 4C2W ANP 5.76923
282 4OCV ANP 5.83554
283 4NW6 2NS 5.88235
284 4YZN 4K5 5.92335
285 5JIB OIA 5.93472
286 3KRL KRL 5.97015
287 3TM0 B31 6.08365
288 3TM0 ANP 6.08365
289 6F3G CJN 6.1017
290 6E2O S0L 6.1017
291 1Q8Y ADP 6.16622
292 1Q8Y ADE 6.16622
293 1RE8 BD2 6.28571
294 2QCS ANP 6.28571
295 3FHI ANP 6.28571
296 3E85 BSU 6.32911
297 2YW2 ATP 6.36605
298 3KAL ADP 6.36605
299 2GU8 796 6.52819
300 3C0G 3AM 6.55271
301 5EOB 5QQ 6.58307
302 5OES ADP 6.6313
303 4G17 0VN 6.66667
304 5DBX ANP 6.70732
305 6GUE FB8 6.71642
306 4X7Q 3YR 6.73077
307 5EYK 5U5 6.77966
308 2BPM 529 6.79245
309 4C2V YJA 6.81818
310 3IDB ANP 6.8323
311 5IH9 6BF 6.86567
312 4BCM T7Z 6.87023
313 4CFU 2WC 6.87023
314 4BCQ TJF 6.87023
315 4BCN T9N 6.87023
316 5MY8 RXZ 6.89655
317 5OMY 9YE 6.90537
318 4F9C 0SX 6.94444
319 3AKK ADP 7.07692
320 3I0O ADP 7.07965
321 5HQ0 LZ9 7.14286
322 6GU6 1QK 7.14286
323 3VRY B43 7.1618
324 4BFM ANP 7.18563
325 4CC6 L5Y 7.2327
326 4O4F IHP 7.25806
327 4O4F ATP 7.25806
328 4WW7 AMP 7.27969
329 3HMO STU 7.30994
330 1U59 STU 7.31707
331 5K2M ADP 7.32601
332 2ZV2 609 7.38255
333 3KN5 ANP 7.38462
334 3DAK ANP 7.58621
335 3GC0 AMP 7.59878
336 3F81 STT 7.65027
337 5CEO 50D 7.66667
338 3K5I ADP 7.69231
339 1T36 ADP 7.69231
340 3K5I AIR 7.69231
341 5MW8 ATP 7.69231
342 1I7L ATP 7.76699
343 5G1X ADP 7.93651
344 2XVD AS6 7.94702
345 5N87 N66 7.98722
346 3PE2 E1B 8.01187
347 3M2W L8I 8.02676
348 2CBT TH2 8.03571
349 2BKK ADP 8.28402
350 5VC5 96M 8.3045
351 3W0O HY0 8.30946
352 3W0O ADP 8.30946
353 5ODT ADP 8.48057
354 5LXM ADP 8.48057
355 3GNI ATP 8.5044
356 5YF9 NIO 8.55457
357 5FI4 5XV 8.66873
358 2VQD AP2 8.75332
359 1M0W ANP 9.01857
360 4QMN DB8 9.03226
361 2YRX AMP 9.09091
362 5HES 032 9.12052
363 1ECM TSA 9.17431
364 2PVN P63 9.375
365 3HZT J60 9.54907
366 5KMS NAD 9.54907
367 4EWH T77 9.81818
368 5UR1 YY9 9.96785
369 2HK5 1BM 10
370 1W2D ADP 10.1887
371 5KK4 44E 10.4167
372 1PK8 ATP 10.6101
373 4CQK PIO 10.6383
374 5YK1 ANP 11.1406
375 5LXT ACP 11.1888
376 3AQV TAK 11.5942
377 5L8L ADP 11.9658
378 2VZ6 FEF 12.1406
379 5NBW 8SK 12.1622
380 1RGE 2GP 12.5
381 1JBU BEN 12.6984
382 1AUX AGS 12.8617
383 2V58 LZJ 13.5857
384 6E2B PT7 14.4737
385 2A19 ANP 14.8571
386 5VZ0 ADP 15.3846
387 4Q5H ANP 15.3846
388 3PVW QRX 15.9151
389 4MV1 ADP 16.6667
390 3VPB ADP 17.3759
391 3VPC ADP 17.3759
392 1TZD ADP 17.4545
393 4USF 6UI 18.0921
394 4Y8D 49J 18.5294
395 3VOT ADP 19.6286
396 5Y80 IRE 20.1278
397 3LQV ADE 20.5128
398 4K55 H6P 20.9677
399 2QF7 AGS 22.2812
400 5ZCT ANP 32.6797
401 5UPK ANP 39.5833
402 1E4E ADP 49.8542
Pocket No.: 2; Query (leader) PDB : 1EHI; Ligand: PHY; Similar sites found with APoc: 18
This union binding pocket(no: 2) in the query (biounit: 1ehi.bio1) has 17 residues
No: Leader PDB Ligand Sequence Similarity
1 5BSZ THM 2.38727
2 5D3X 4IP 2.39521
3 5JAQ NAI 2.65252
4 2ZUV NDG 2.65252
5 4X3R 686 2.91777
6 1LDN NAD 3.16456
7 5HCN DAO 3.83142
8 4EUE NAI 4.24403
9 3LA3 2FT 6.17284
10 1T36 ADP 7.69231
11 3VPH NAD 8.06452
12 3VPH OXM 8.06452
13 4S28 AIR 8.22281
14 4S28 SAH 8.22281
15 4ZVV NAD 8.43373
16 4ZVV GN0 8.43373
17 2XKO AKG 20.2247
18 1E4E PHY 49.8542
APoc FAQ
Feedback