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Receptor
PDB id Resolution Class Description Source Keywords
1EP1 2.2 Å EC: 1.3.3.1 CRYSTAL STRUCTURE OF LACTOCOCCUS LACTIS DIHYDROOROTATE DEHYD LACTOCOCCUS LACTIS HETEROTETRAMER OXIDOREDUCTASE
Ref.: STRUCTURE OF DIHYDROOROTATE DEHYDROGENASE B: ELECTR TRANSFER BETWEEN TWO FLAVIN GROUPS BRIDGED BY AN IRON-SULPHUR CLUSTER. STRUCTURE FOLD.DES. V. 8 1227 2000
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
FAD B:502;
Valid;
none;
submit data
785.55 C27 H33 N9 O15 P2 Cc1cc...
FES B:503;
Part of Protein;
none;
submit data
175.82 Fe2 S2 S1[Fe...
FMN A:501;
Valid;
none;
submit data
456.344 C17 H21 N4 O9 P Cc1cc...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1EP2 2.4 Å EC: 1.3.3.1 CRYSTAL STRUCTURE OF LACTOCOCCUS LACTIS DIHYDROOROTATE DEHYD COMPLEXED WITH OROTATE LACTOCOCCUS LACTIS HETEROTETRAMER OXIDOREDUCTASE
Ref.: STRUCTURE OF DIHYDROOROTATE DEHYDROGENASE B: ELECTR TRANSFER BETWEEN TWO FLAVIN GROUPS BRIDGED BY AN IRON-SULPHUR CLUSTER. STRUCTURE FOLD.DES. V. 8 1227 2000
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 1EP3 - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
2 1EP1 - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
3 1EP2 - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
70% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 1EP3 - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
2 1EP1 - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
3 1EP2 - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
50% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 1EP3 - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
2 1EP1 - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
3 1EP2 - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: FAD; Similar ligands found: 128
No: Ligand ECFP6 Tc MDL keys Tc
1 FAD 1 1
2 FAS 1 1
3 FAY 0.859259 0.9875
4 RFL 0.852941 0.963855
5 6FA 0.794118 0.987654
6 FAE 0.751773 0.987654
7 SFD 0.651007 0.860215
8 FDA 0.641892 0.906977
9 FNK 0.602564 0.876405
10 62F 0.572327 0.939024
11 F2N 0.566265 0.886364
12 FMN 0.543307 0.876543
13 FA9 0.526316 0.939759
14 6YU 0.516304 0.860215
15 P6G FDA 0.511628 0.908046
16 FAD NBT 0.508876 0.83871
17 A2D 0.504065 0.875
18 P5F 0.491329 0.941176
19 FAD CNX 0.488506 0.8125
20 AR6 0.488372 0.851852
21 APR 0.488372 0.851852
22 AGS 0.484615 0.811765
23 SAP 0.484615 0.811765
24 M33 0.484375 0.864198
25 BA3 0.484127 0.875
26 HEJ 0.48062 0.851852
27 ATP 0.48062 0.851852
28 ADP 0.480315 0.851852
29 B4P 0.480315 0.875
30 AP5 0.480315 0.875
31 ANP 0.477273 0.831325
32 AQP 0.476923 0.851852
33 5FA 0.476923 0.851852
34 48N 0.469388 0.902439
35 OAD 0.467626 0.876543
36 9X8 0.467626 0.833333
37 FAD NBA 0.467033 0.793814
38 GTA 0.465753 0.892857
39 AN2 0.465116 0.841463
40 AT4 0.465116 0.821429
41 AD9 0.462121 0.831325
42 3OD 0.460993 0.876543
43 RBF 0.460938 0.790123
44 FB0 0.460606 0.835165
45 139 0.460526 0.858824
46 AP0 0.46 0.835294
47 A22 0.459854 0.864198
48 ACP 0.458015 0.853659
49 8QN 0.456522 0.864198
50 PRX 0.454545 0.831325
51 A3R 0.453237 0.86747
52 A1R 0.453237 0.86747
53 G3A 0.452055 0.902439
54 T5A 0.45098 0.872093
55 G5P 0.44898 0.902439
56 ATF 0.448529 0.821429
57 50T 0.44697 0.819277
58 6YZ 0.445255 0.853659
59 ACQ 0.444444 0.853659
60 CNV FAD 0.443182 0.917647
61 ADQ 0.442857 0.853659
62 PAJ 0.442857 0.847059
63 5AL 0.441176 0.864198
64 ADX 0.439394 0.775281
65 CA0 0.439394 0.853659
66 A4P 0.437909 0.831461
67 25L 0.4375 0.864198
68 P33 FDA 0.436464 0.817204
69 5SV 0.435714 0.793103
70 OMR 0.434211 0.818182
71 TXE 0.434211 0.890244
72 ABM 0.434109 0.829268
73 A 0.433071 0.82716
74 AMP 0.433071 0.82716
75 4AD 0.432624 0.855422
76 ADJ 0.432258 0.818182
77 B5M 0.431507 0.878049
78 B5Y 0.431507 0.878049
79 BIS 0.430556 0.802326
80 SRA 0.429688 0.788235
81 AFH 0.42953 0.825581
82 NXX 0.427632 0.865854
83 DND 0.427632 0.865854
84 UP5 0.427632 0.878049
85 6V0 0.427632 0.857143
86 TXD 0.427632 0.890244
87 DQV 0.426667 0.8875
88 SRP 0.42446 0.843373
89 PR8 0.423611 0.837209
90 T99 0.423358 0.821429
91 TAT 0.423358 0.821429
92 AMO 0.422535 0.865854
93 TXA 0.42069 0.865854
94 FYA 0.42069 0.864198
95 PTJ 0.42069 0.835294
96 CNA 0.420382 0.865854
97 00A 0.41958 0.823529
98 AHX 0.41958 0.835294
99 MAP 0.41844 0.811765
100 NAI 0.418301 0.845238
101 AU1 0.41791 0.831325
102 A12 0.416667 0.843373
103 AP2 0.416667 0.843373
104 25A 0.415493 0.851852
105 9ZA 0.415493 0.845238
106 9ZD 0.415493 0.845238
107 COD 0.415094 0.842697
108 4TC 0.412903 0.879518
109 APC 0.411765 0.843373
110 ME8 0.410959 0.806818
111 1ZZ 0.410959 0.806818
112 NB8 0.410959 0.835294
113 4UW 0.409091 0.825581
114 NAX 0.409091 0.837209
115 F2R 0.408805 0.850575
116 RBY 0.408759 0.843373
117 ADV 0.408759 0.843373
118 P1H 0.405882 0.818182
119 OOB 0.405594 0.864198
120 LAD 0.40411 0.825581
121 A A 0.40411 0.829268
122 UPA 0.403846 0.86747
123 4UU 0.401316 0.833333
124 GA7 0.401316 0.865854
125 A3D 0.401235 0.876543
126 80F 0.401235 0.808989
127 XAH 0.4 0.806818
128 DLL 0.4 0.864198
Ligand no: 2; Ligand: FMN; Similar ligands found: 15
No: Ligand ECFP6 Tc MDL keys Tc
1 FMN 1 1
2 RBF 0.75641 0.876712
3 RS3 0.571429 0.831169
4 FAD 0.543307 0.876543
5 FAS 0.543307 0.876543
6 FAE 0.539062 0.865854
7 LFN 0.475 0.643836
8 C3F 0.473684 0.74359
9 CF4 0.463918 0.734177
10 FAY 0.446043 0.864198
11 FNR 0.444444 0.909091
12 RFL 0.442857 0.845238
13 4LS 0.411215 0.875
14 1VY 0.406593 0.769231
15 DLZ 0.404494 0.782051
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1EP2; Ligand: FAD; Similar sites found with APoc: 115
This union binding pocket(no: 1) in the query (biounit: 1ep2.bio1) has 25 residues
No: Leader PDB Ligand Sequence Similarity
1 2BSA FAD 2.68199
2 2BSA NAP 2.68199
3 6GEH FAD 3.125
4 1T9M FMN 3.27103
5 2R4J FAD 3.44828
6 2R4J 13P 3.44828
7 1GAW FAD 3.83142
8 5VLQ ANP 3.83142
9 6EGU 43Y 3.83142
10 5WXU FLC 3.85852
11 3FSY SCA 3.85852
12 4E28 9MZ 4
13 5FA6 FAD 4.21456
14 5FA6 FMN 4.21456
15 5FA6 NAP 4.21456
16 3QFS FAD 4.21456
17 3QFS NAP 4.21456
18 1DDG FAD 4.21456
19 4AGS GSH 4.24628
20 1A8P FAD 4.26357
21 3K87 FAD 4.32432
22 3EJ0 11X 4.59184
23 3MHP FAD 4.5977
24 1QFY FAD 4.5977
25 1QFY NAP 4.5977
26 5LFV SIA GAL NAG 4.5977
27 1RJW ETF 4.5977
28 1KZL CRM 4.80769
29 3SJK LYS PRO VAL LEU ARG THR ALA 5.26316
30 2QTZ FAD 5.36398
31 2QTZ NAP 5.36398
32 4G1V FAD 5.36398
33 3CRZ FAD 5.44747
34 3CRZ NAP 5.44747
35 5W7B MYR 5.67376
36 1NE7 16G 5.88235
37 1B74 DGN 5.90551
38 5GXU FAD 6.13027
39 3S6X SIA GAL BGC 6.13027
40 1USF NAP 6.17978
41 1USF FMN 6.17978
42 5DCH 1YO 6.25
43 3A76 SPD 6.25
44 3ZOD FMN 6.28272
45 3ZOD HQE 6.28272
46 1RZM E4P 6.51341
47 3A3B FMN 6.84211
48 3A3B RBF 6.84211
49 1WK9 TSB 6.84932
50 4HMX FMN 6.97674
51 2NZ5 226 7.27969
52 1B4N GUA 7.3955
53 3UEC ALA ARG TPO LYS 7.53425
54 3R5Z F42 7.58621
55 5KIQ SIA GAL NAG FUC 7.61421
56 3JQQ FAD 7.66284
57 3JQQ A2P 7.66284
58 4OFJ HIS 7.71704
59 5VKM GAL SIA 8.04598
60 4F9U PBD 8.04598
61 4ZTE 4RL 8.05687
62 6CI9 F3V 8.10811
63 2VNI FAD 8.42912
64 2VNI A2P 8.42912
65 4YBN FAD 8.48214
66 4ARU TLA 9.1954
67 1FND FAD 9.1954
68 1FND A2P 9.1954
69 2XOC ADP 9.1954
70 1RGE 2GP 9.375
71 4QVB F42 9.52381
72 4YHB FAD 9.52381
73 1JH7 UVC 9.52381
74 4DS0 A2G GAL NAG FUC 9.81595
75 1TLL FAD 9.96169
76 1F20 FAD 9.96169
77 5D63 FUC GAL GLA 9.96169
78 2ZWS PLM 9.96169
79 4F07 FAD 10.5263
80 4NRT 2NG 10.728
81 3FJO FAD 10.9325
82 4YH2 GSH 11.2613
83 3R5W F42 11.6071
84 1PVC ILE SER GLU VAL 13.2353
85 4G6I RS3 13.3333
86 3QX9 ATP 13.7681
87 5H5J FAD 15.3257
88 5VW2 NAP 15.3257
89 5VW2 FDA 15.3257
90 3CB0 FMN 15.6069
91 3OZV FAD 16.7203
92 3OZV ECN 16.7203
93 5O0X FAD 16.8582
94 2CND FAD 16.8582
95 5E6O TRP GLU GLU LEU 16.9492
96 1SM4 FAD 18.3908
97 4DQL NAP 18.7739
98 4DQL FAD 18.7739
99 3W2E FAD 19.5402
100 3W2E NAD 19.5402
101 1QX4 FAD 19.9234
102 1EWY FAD 20.4082
103 2XNJ NAP 20.6897
104 2XNJ FAD 20.6897
105 1KRH FAD 22.2222
106 3VO1 FAD 22.2222
107 4U9U FAD 22.2222
108 5YLY FAD 23.7548
109 2RC5 FAD 24.9042
110 4B4D FAD 28.3525
111 5OGX FAD 30.2682
112 2EIX FAD 32.5103
113 2PIA FMN 33.3333
114 4WQM FAD 33.7165
115 5JCA FAD 47.8927
Pocket No.: 2; Query (leader) PDB : 1EP2; Ligand: FAD; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 1ep2.bio1) has 25 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 1EP2; Ligand: ORO; Similar sites found with APoc: 307
This union binding pocket(no: 3) in the query (biounit: 1ep2.bio1) has 35 residues
No: Leader PDB Ligand Sequence Similarity
1 4WG0 CHD None
2 4X7Q 3YR 1.92926
3 4M5P FMN 2.29885
4 3VGL ANP 2.29885
5 1TZJ A3B 2.29885
6 1QMG DMV 2.57235
7 4YNM SAM 2.65487
8 3G2Y GF4 2.6616
9 5UI2 SUC 2.68199
10 4PVR ASP 2.68199
11 2FUE M1P 3.05344
12 3BRE C2E 3.06513
13 1J1R ADE 3.06513
14 5FWJ MMK 3.06513
15 3WY9 GDP 3.06513
16 2BJ4 OHT 3.1746
17 5OCS FMN 3.21543
18 1VYP FMN 3.21543
19 1VYP TNF 3.21543
20 1FDJ 13P 3.21543
21 1FDJ 2FP 3.21543
22 1C3V PDC 3.26531
23 6A5K SAM 3.44828
24 1VMK GUN 3.44828
25 1QVJ RP5 3.44828
26 2GVV DI9 3.44828
27 5JBX MLI 3.44828
28 3G1Z AMP 3.44828
29 5OES ADP 3.44828
30 4BI7 PGA 3.50195
31 6CEN SAM 3.50877
32 4A59 AMP 3.53698
33 6B9T 2HE 3.53698
34 2YPI PGA 3.64372
35 2J9L ATP 3.78378
36 5VLQ ANP 3.83142
37 4YMJ 4EJ 3.83142
38 4MJ0 SIA SIA 3.83142
39 4I9A NCN 3.83142
40 1XXA ARG 3.84615
41 1TB3 FMN 3.85852
42 4A3U FMN 3.85852
43 4LHD GLY 3.85852
44 2HJR CIT 3.85852
45 6C4A PYR 3.85852
46 1TKK ALA GLU 3.85852
47 1LYX PGA 4.03226
48 3EXS 5RP 4.0724
49 4QBK 3NZ 4.12371
50 5J75 6GQ 4.16667
51 4NOS ITU 4.18006
52 1Z44 FMN 4.21456
53 1Z48 FMN 4.21456
54 1Z41 FMN 4.21456
55 4B47 GDP 4.21456
56 1Z42 FMN 4.21456
57 3HUN ZZ7 4.21456
58 4Z1D PEP 4.21456
59 5U5G 7VD 4.21456
60 4GN8 ASO 4.34783
61 4AU8 Z3R 4.39189
62 4NAE 1GP 4.44444
63 5UJ3 CE4 4.48276
64 3GD8 GOL 4.4843
65 2YFO GAL 4.50161
66 2YFO GLA 4.50161
67 3GC0 AMP 4.50161
68 1OYB HBA 4.5977
69 1OYB FMN 4.5977
70 2VVM PRO 4.5977
71 4D52 GXL 4.5977
72 1NX4 AKG 4.5977
73 3QPB URA 4.60993
74 5AVF TAU 4.66926
75 6DAW ARG 4.67836
76 1OFD AKG 4.82315
77 1OFD FMN 4.82315
78 1GVF PGH 4.8951
79 1M5W DXP 4.93827
80 4TMC HBA 4.98084
81 4TMC FMN 4.98084
82 5YT0 GDP 4.98084
83 5FG3 GDP 4.98084
84 1OHE ACE ALA SEP PRO 4.98084
85 4FUA PGH 5.11628
86 6BKA FMN 5.14469
87 1ICP FMN 5.14469
88 2Q3R FMN 5.14469
89 3ESS 18N 5.21739
90 1P6D 3PC 5.30612
91 1ULE GLA GAL NAG 5.33333
92 5YLF BGC 5.36398
93 2YRX AMP 5.36398
94 4UP4 GAL NAG 5.36398
95 5G09 6DF 5.36398
96 5ZBL AMP 5.41872
97 6DVH FMN 5.46624
98 4K10 NI9 5.46624
99 4FE2 AIR 5.4902
100 3CTL S6P 5.62771
101 2R14 FMN 5.74713
102 2R14 TXD 5.74713
103 3TII ANP 5.74713
104 4HSJ 6PC 5.74713
105 2PYW ADP 5.74713
106 2HBL AMP 5.78778
107 4TUZ 36J 5.88235
108 4K7O EKZ 5.95238
109 1D1G MTX 5.95238
110 5D3X 4IP 5.98802
111 4DKX GDP 6.01852
112 6H45 QEI 6.10932
113 4IVN BMX 6.11511
114 5JH2 A2P 6.12903
115 5LUB 3Y7 6.13027
116 5MB4 NAG 6.13027
117 5DKK FMN 6.2069
118 3HRD NIO 6.25
119 1QDS PGA 6.3745
120 3PGU OLA 6.43087
121 2HSA FMN 6.51341
122 6GH3 M1P 6.51341
123 4CQB MLI 6.51341
124 2C6Q IMP 6.51341
125 1V0O INR 6.59722
126 1Y13 BIO 6.62983
127 6A46 DCM 6.64062
128 3WCS MAN NAG 6.69291
129 2F2G HMH 6.78733
130 4DOO DAO 6.82927
131 5W75 SUC 6.89655
132 3VNM SDD 6.89655
133 4MZQ 1VU 6.94444
134 1EWK GLU 7.07396
135 4RYV ZEA 7.09677
136 2BTM PGA 7.14286
137 4G2R H1L 7.18816
138 1P4C FMN 7.27969
139 4QNW FMN 7.27969
140 5CPR SAM 7.27969
141 2F7A BEZ 7.32759
142 4AOA IK2 7.3955
143 3OVR 5SP 7.45614
144 2PW0 TRC 7.66284
145 5M04 GDP 7.66284
146 5JZJ AN2 7.66284
147 1DCP HBI 7.69231
148 2GBB CIT 7.69231
149 2Z6I FMN 7.71704
150 5T52 NGA 7.85124
151 5T52 A2G 7.85124
152 4FGC PQ0 7.87879
153 2DBX GLU 7.89474
154 4YMZ 13P 7.96813
155 5EYW PGA 8.03213
156 1GPJ CIT 8.04598
157 6BXI ANP 8.04598
158 1EB9 HBA 8.04598
159 1Q6O LG6 8.33333
160 2H8Z 8CM 8.36013
161 2H8Z FMN 8.36013
162 4RKK GLC GLC GLC GLC GLC GLC 8.36013
163 1VRP ADP 8.36013
164 1YFS ALA 8.36013
165 1J78 VDY 8.36013
166 1NJJ ORX 8.36013
167 1PS9 FMN 8.42912
168 1SW0 PGA 8.46774
169 2F6U CIT 8.54701
170 3GGF GVD 8.63787
171 3KRU FMN 8.68167
172 2Z6J FMN 8.68167
173 3TAO PGH 8.81226
174 3DAK ANP 8.81226
175 5AHN IMP 9.00322
176 1TRD PGH 9.00322
177 2Q3O FMN 9.00322
178 1WDD CAP 9.00322
179 5JLB SAH 9.319
180 2RDT FMN 9.32476
181 2RDT 2RD 9.32476
182 4Q4K FMN 9.32476
183 4IXH IMP 9.32476
184 1U6R ADP 9.32476
185 2CJW GDP 9.375
186 1FUT 2GP 9.43396
187 6GU6 1QK 9.52381
188 1UZD CAP 9.6463
189 1IR2 CAP 9.6463
190 2OEM 1AE 9.96785
191 4YEE 4CQ 10
192 5AHM IMP 10
193 3BP1 GUN 10
194 3AXK NDP 10.0775
195 6BVE PGA 10.2041
196 5LOL GSH 10.2326
197 6GNF GLC 10.2894
198 5JDA AMP 10.2894
199 3GQT UFO 10.2894
200 2HT6 GDP 10.3448
201 1ZFJ IMP 10.3448
202 3UXM 0DN 10.4265
203 2OYH GLY HIS ARG PRO 10.6061
204 6BFG FMN 10.6109
205 1OX5 1PR 10.6109
206 5M45 AMP 10.7143
207 4R3U 5AD 10.728
208 5H9I XAN 10.8333
209 1SQL GUN 10.9589
210 2W5P CL8 11.4094
211 2HVW DDN 11.413
212 2NUO BGC 11.4754
213 2GUC MAN 11.4754
214 1AL8 DHP 11.4943
215 1AL8 FMN 11.4943
216 5WGD EST 11.4943
217 2REG CHT 11.4943
218 5N9Z CAP 11.5108
219 4V15 PLP 11.5756
220 4MG8 27J 11.7647
221 4UTU LRY 11.7904
222 4UTW RFW 11.7904
223 3UUD EST 11.9522
224 1DJN FMN 12.2186
225 3G6M CFF 12.2186
226 3A75 GLU 12.2605
227 4CW5 FMN 12.2605
228 3H0A 9RA 12.2807
229 6BSX E7S 12.3596
230 4AF0 IMP 12.5402
231 3QXV MTX 12.6984
232 1VCE SAH 12.8302
233 4LRJ ANP 13.0178
234 4ZM4 P3B 13.0268
235 5TCI MLI 13.0435
236 4EWN 0VR 13.0435
237 1UZH CAP 13.1148
238 1WNG SAH 13.2075
239 2IDO TMP 13.253
240 4JIQ 1L5 13.41
241 4JIQ FMN 13.41
242 3VY6 BGC BGC 13.4752
243 4JEJ 1GP 13.5246
244 3QH2 3NM 13.5747
245 1RBL CAP 13.7615
246 2ZRU FMN 13.7931
247 2GOU FMN 13.7931
248 5CIC 51R 13.7931
249 1M0W ANP 13.7931
250 3ATY FMN 13.8264
251 3BW2 FMN 13.8264
252 4NPT 017 14.1414
253 3Q72 GNP 14.4578
254 5CSS G3P 14.6018
255 4IMG NGF 14.6758
256 2OO0 PLP 16.092
257 6E1Q CFA 16.3987
258 2V67 CAP 16.4286
259 2V6A CAP 16.4286
260 2V68 CAP 16.4286
261 2V63 CAP 16.4286
262 2VDH CAP 16.4286
263 1KBJ FMN 17.0418
264 1KBI PYR 17.3633
265 1KBI FMN 17.3633
266 5TDU PCR 17.4757
267 1B4B ARG 18.3099
268 2NLI FMN 18.328
269 2NLI LAC 18.328
270 2HKA C3S 18.4615
271 1VBO MAN MAN MAN 18.7919
272 5YRV 5AD 18.9781
273 5TQZ GLC 19.3333
274 3HF3 FMN 19.5402
275 2FLI DX5 19.5455
276 4NTK ZSP 19.8347
277 1W8S FBP 20.1521
278 5GVH FMN 20.2572
279 2GJN NIS 20.9003
280 2GJN FMN 20.9003
281 3GLC R5P 21.0728
282 1N8V BDD 21.4286
283 4N02 FNR 21.4559
284 3W9Z FMN 21.5434
285 1VHN FMN 21.865
286 5YRI GLC GLC 22.5352
287 3B0P FMN 27.3312
288 1NBU PH2 27.7311
289 4XP7 FNR 28.6174
290 4ORM 2V6 39.2283
291 4ORM ORO 39.2283
292 4ORM FMN 39.2283
293 1TV5 FMN 40.836
294 1TV5 ORO 40.836
295 3OIX FMN 42.4437
296 5XFV FMN 45.0161
297 4WZH FMN 45.6592
298 1OVD ORO 46.6238
299 1OVD FMN 46.6238
300 1UUO BRF 47.2669
301 1UUO ORO 47.2669
302 1UUO FMN 47.2669
303 1GTE IUR 47.2669
304 1GTE FMN 47.2669
305 4IGH ORO 47.91
306 4IGH FMN 47.91
307 4IGH 1EA 47.91
Pocket No.: 4; Query (leader) PDB : 1EP2; Ligand: ORO; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 1ep2.bio1) has 35 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 5; Query (leader) PDB : 1EP2; Ligand: FMN; Similar sites found with APoc: 242
This union binding pocket(no: 5) in the query (biounit: 1ep2.bio1) has 29 residues
No: Leader PDB Ligand Sequence Similarity
1 4WG0 CHD None
2 4M5P FMN 2.29885
3 3VGL ANP 2.29885
4 3G2Y GF4 2.6616
5 4PVR ASP 2.68199
6 3BRE C2E 3.06513
7 5OCS FMN 3.21543
8 1VYP FMN 3.21543
9 1VYP TNF 3.21543
10 1FDJ 13P 3.21543
11 1FDJ 2FP 3.21543
12 5JBX MLI 3.44828
13 1PVN MZP 3.45745
14 4BI7 PGA 3.50195
15 4A59 AMP 3.53698
16 6B9T 2HE 3.53698
17 3FYP PEP 3.57143
18 2YPI PGA 3.64372
19 5B2E MQG 3.67647
20 3ETG GTP 3.83142
21 4MJ0 SIA SIA 3.83142
22 4I9A NCN 3.83142
23 1XXA ARG 3.84615
24 1TB3 FMN 3.85852
25 4A3U FMN 3.85852
26 2HJR CIT 3.85852
27 1LYX PGA 4.03226
28 3EXS 5RP 4.0724
29 3HQP FDP 4.18006
30 1Z44 FMN 4.21456
31 1Z48 FMN 4.21456
32 1Z41 FMN 4.21456
33 1Z42 FMN 4.21456
34 3HUN ZZ7 4.21456
35 4Z1D PEP 4.21456
36 4WOE ADP 4.21456
37 4AU8 Z3R 4.39189
38 4NAE 1GP 4.44444
39 3GD8 GOL 4.4843
40 1KKR 2AS 4.50161
41 1OYB FMN 4.5977
42 1OYB HBA 4.5977
43 4D52 GXL 4.5977
44 3QPB URA 4.60993
45 5AVF TAU 4.66926
46 6DAW ARG 4.67836
47 1OFD AKG 4.82315
48 1OFD FMN 4.82315
49 5EXK MET 4.82315
50 1GVF PGH 4.8951
51 1M5W DXP 4.93827
52 4TMC FMN 4.98084
53 4TMC HBA 4.98084
54 1OHE ACE ALA SEP PRO 4.98084
55 5V6F MAN BMA MAN 5.07246
56 6BKA FMN 5.14469
57 2Q3R FMN 5.14469
58 1ICP FMN 5.14469
59 3ESS 18N 5.21739
60 5YLF BGC 5.36398
61 2AWN ADP 5.36398
62 2YRX AMP 5.36398
63 5A7V BMA 5.36398
64 5A7V MAN 5.36398
65 6DVH FMN 5.46624
66 4FE2 AIR 5.4902
67 3CTL S6P 5.62771
68 2R14 FMN 5.74713
69 2R14 TXD 5.74713
70 4M3P HCS 5.74713
71 5DMZ ADP 5.74713
72 5ZXD ATP 5.78778
73 3WXL ADP 5.78778
74 1NE7 16G 5.88235
75 4K7O EKZ 5.95238
76 5D3X 4IP 5.98802
77 1OYJ GSH 6.06061
78 6H45 QEI 6.10932
79 5LUB 3Y7 6.13027
80 1QDS PGA 6.3745
81 2HSA FMN 6.51341
82 1KGZ PRP 6.51341
83 4FG8 ATP 6.51341
84 5HX1 UMP 6.52174
85 4OWK NGA 6.52174
86 1V0O INR 6.59722
87 1Y13 BIO 6.62983
88 3WCS MAN NAG 6.69291
89 2F2G HMH 6.78733
90 5W75 SUC 6.89655
91 3VNM SDD 6.89655
92 4MZQ 1VU 6.94444
93 1X9I G6Q 6.95364
94 5KXE 6Y2 6.99588
95 1EWK GLU 7.07396
96 4RYV ZEA 7.09677
97 2BTM PGA 7.14286
98 4G2R H1L 7.18816
99 4QNW FMN 7.27969
100 1P4C FMN 7.27969
101 4AOA IK2 7.3955
102 3OVR 5SP 7.45614
103 2PW0 TRC 7.66284
104 5JZJ AN2 7.66284
105 2ZQO NGA 7.69231
106 1DCP HBI 7.69231
107 2Z6I FMN 7.71704
108 2CBO TH2 7.82609
109 4FGC PQ0 7.87879
110 2DBX GLU 7.89474
111 4YMZ 13P 7.96813
112 5EYW PGA 8.03213
113 1Q6O LG6 8.33333
114 2H8Z 8CM 8.36013
115 2H8Z FMN 8.36013
116 1VRP ADP 8.36013
117 1PS9 FMN 8.42912
118 1SW0 PGA 8.46774
119 2F6U CIT 8.54701
120 3GGF GVD 8.63787
121 2Z6J FMN 8.68167
122 3KRU FMN 8.68167
123 3TAO PGH 8.81226
124 5AHN IMP 9.00322
125 2Q3O FMN 9.00322
126 1TRD PGH 9.00322
127 5A1S FLC 9.00322
128 5ECP GSH 9.00322
129 1WDD CAP 9.00322
130 3GL0 HXX 9.1954
131 4Q4K FMN 9.32476
132 2RDT FMN 9.32476
133 2RDT 2RD 9.32476
134 4IXH IMP 9.32476
135 1U6R ADP 9.32476
136 2VZ6 FEF 9.32476
137 6GU6 1QK 9.52381
138 2X2M X2M 9.55414
139 1UZD CAP 9.6463
140 1IR2 CAP 9.6463
141 2HK1 FUD 9.70874
142 2OEM 1AE 9.96785
143 2P4S DIH 9.96785
144 1T9D PYD 9.96785
145 3BP1 GUN 10
146 3AXK NDP 10.0775
147 6BVE PGA 10.2041
148 5A5W GUO 10.2767
149 6GNF GLC 10.2894
150 5JDA AMP 10.2894
151 6BFG FMN 10.6109
152 1OX5 1PR 10.6109
153 4AMW 5DI 10.6109
154 1SQL GUN 10.9589
155 2W5P CL8 11.4094
156 2NUO BGC 11.4754
157 2GUC MAN 11.4754
158 1AL8 FMN 11.4943
159 1AL8 DHP 11.4943
160 5J5R IMP 11.4943
161 5J5R 6G1 11.4943
162 5N9Z CAP 11.5108
163 4V15 PLP 11.5756
164 6HT0 GQ8 11.6129
165 4UTU LRY 11.7904
166 4UTW RFW 11.7904
167 1DJN FMN 12.2186
168 3A75 GLU 12.2605
169 4CW5 FMN 12.2605
170 6BSX E7S 12.3596
171 4AF0 IMP 12.5402
172 3QXV MTX 12.6984
173 4ZM4 P3B 13.0268
174 5ODQ 9SB 13.0268
175 5TCI MLI 13.0435
176 4EWN 0VR 13.0435
177 1UZH CAP 13.1148
178 5Z2F PDC 13.2075
179 2IDO TMP 13.253
180 4JIQ 1L5 13.41
181 4JIQ FMN 13.41
182 3VY6 BGC BGC 13.4752
183 4JEJ 1GP 13.5246
184 3QH2 3NM 13.5747
185 2ZRU FMN 13.7931
186 2GOU FMN 13.7931
187 5CIC 51R 13.7931
188 3BW2 FMN 13.8264
189 3ATY FMN 13.8264
190 3DG6 MUC 14.1762
191 6GR0 F8W 14.3678
192 5CSS G3P 14.6018
193 2Y88 2ER 14.7541
194 4URS C2E 14.8936
195 4M26 AKG 15.3257
196 2OO0 PLP 16.092
197 6E1Q CFA 16.3987
198 2V67 CAP 16.4286
199 2V6A CAP 16.4286
200 2V68 CAP 16.4286
201 2V63 CAP 16.4286
202 5O0X FAD 16.8582
203 1KBJ FMN 17.0418
204 1KBI FMN 17.3633
205 1KBI PYR 17.3633
206 2NLI FMN 18.328
207 2NLI LAC 18.328
208 5YRV 5AD 18.9781
209 3AI3 SOE 19.1571
210 3HF3 FMN 19.5402
211 2FLI DX5 19.5455
212 4NTM 2K8 19.8347
213 4NTK ZSP 19.8347
214 1W8S FBP 20.1521
215 5GVH FMN 20.2572
216 2GJN NIS 20.9003
217 2GJN FMN 20.9003
218 3GLC R5P 21.0728
219 4N02 FNR 21.4559
220 3W9Z FMN 21.5434
221 1VHN FMN 21.865
222 5YRI GLC GLC 22.5352
223 3B0P FMN 27.3312
224 1NBU PH2 27.7311
225 4XP7 FNR 28.6174
226 4ORM 2V6 39.2283
227 4ORM ORO 39.2283
228 4ORM FMN 39.2283
229 1TV5 FMN 40.836
230 3OIX FMN 42.4437
231 5XFV FMN 45.0161
232 4WZH FMN 45.6592
233 1OVD ORO 46.6238
234 1OVD FMN 46.6238
235 1GTE FMN 47.2669
236 1GTE IUR 47.2669
237 1UUO ORO 47.2669
238 1UUO FMN 47.2669
239 1UUO BRF 47.2669
240 4IGH 1EA 47.91
241 4IGH ORO 47.91
242 4IGH FMN 47.91
Pocket No.: 6; Query (leader) PDB : 1EP2; Ligand: FMN; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 6) in the query (biounit: 1ep2.bio1) has 29 residues
No: Leader PDB Ligand Sequence Similarity
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