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Receptor
PDB id Resolution Class Description Source Keywords
1FK8 1.95 Å EC: 1.1.1.50 THE CRYSTAL STRUCTURE OF THE BINARY COMPLEX WITH NAD OF 3-AL HYDROXYSTEROID DEHYDROGENASE FROM COMAMONAS TESTOSTERONI, AT HE SHORT CHAIN DEHYDROGENASE/REDUCTASE FAMILY COMAMONAS TESTOSTERONI SHORT CHAIN DEHYDROGENASE SDR CARBONYL REDUCTASE STEROIDHYDROXYSTEROID XENOBIOTIC METYRAPONE OLIGOMERISATION COTESTOSTERONI NAD NICOTINAMIDE ADENINE DINUCLEOTIDE SUBSTBINDING LOOP OXIDOREDUCTASE
Ref.: THE CRYSTAL STRUCTURE OF 3ALPHA -HYDROXYSTEROID DEHYDROGENASE/CARBONYL REDUCTASE FROM COMAMONAS TES SHOWS A NOVEL OLIGOMERIZATION PATTERN WITHIN THE SH DEHYDROGENASE/REDUCTASE FAMILY. J.BIOL.CHEM. V. 275 41333 2000
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
NAD A:800;
B:1800;
Valid;
Valid;
none;
none;
submit data
663.425 C21 H27 N7 O14 P2 c1cc(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1FK8 1.95 Å EC: 1.1.1.50 THE CRYSTAL STRUCTURE OF THE BINARY COMPLEX WITH NAD OF 3-AL HYDROXYSTEROID DEHYDROGENASE FROM COMAMONAS TESTOSTERONI, AT HE SHORT CHAIN DEHYDROGENASE/REDUCTASE FAMILY COMAMONAS TESTOSTERONI SHORT CHAIN DEHYDROGENASE SDR CARBONYL REDUCTASE STEROIDHYDROXYSTEROID XENOBIOTIC METYRAPONE OLIGOMERISATION COTESTOSTERONI NAD NICOTINAMIDE ADENINE DINUCLEOTIDE SUBSTBINDING LOOP OXIDOREDUCTASE
Ref.: THE CRYSTAL STRUCTURE OF 3ALPHA -HYDROXYSTEROID DEHYDROGENASE/CARBONYL REDUCTASE FROM COMAMONAS TES SHOWS A NOVEL OLIGOMERIZATION PATTERN WITHIN THE SH DEHYDROGENASE/REDUCTASE FAMILY. J.BIOL.CHEM. V. 275 41333 2000
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 1FK8 - NAD C21 H27 N7 O14 P2 c1cc(c[n+]....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 1FK8 - NAD C21 H27 N7 O14 P2 c1cc(c[n+]....
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 1FK8 - NAD C21 H27 N7 O14 P2 c1cc(c[n+]....
2 2DKN Kd = 8.8 uM NAI C21 H29 N7 O14 P2 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: NAD; Similar ligands found: 230
No: Ligand ECFP6 Tc MDL keys Tc
1 A3D 0.872727 0.986111
2 NHD 0.821429 0.972222
3 NAP 0.811966 0.986111
4 NFD 0.791304 0.946667
5 NXX 0.765766 0.972603
6 DND 0.765766 0.972603
7 AMP NAD 0.74359 0.972222
8 ZID 0.737705 0.986111
9 NAQ 0.729508 0.934211
10 NAE 0.721311 0.959459
11 NA0 0.712 0.972603
12 TAP 0.704 0.921053
13 NDE 0.689922 0.972603
14 NAJ 0.683333 0.972222
15 NDC 0.679389 0.934211
16 NDO 0.674603 0.958904
17 N01 0.656 0.972222
18 CNA 0.642276 0.972603
19 NBP 0.621212 0.922078
20 8ID 0.609756 0.922078
21 A2D 0.576923 0.958333
22 ADP 0.575472 0.931507
23 NGD 0.574803 0.922078
24 BA3 0.566038 0.958333
25 M33 0.564815 0.918919
26 ADP PO3 0.563636 0.957747
27 B4P 0.560748 0.958333
28 AP5 0.560748 0.958333
29 AN2 0.555556 0.918919
30 AT4 0.555556 0.894737
31 GAP 0.553571 0.932432
32 OOB 0.551724 0.972222
33 CA0 0.550459 0.932432
34 9JJ 0.546053 0.898734
35 HEJ 0.545455 0.931507
36 ACP 0.545455 0.906667
37 ATP 0.545455 0.931507
38 DQV 0.544 0.972222
39 ADP ALF 0.54386 0.883117
40 ALF ADP 0.54386 0.883117
41 DAL AMP 0.543103 0.945205
42 APR 0.540541 0.931507
43 AQP 0.540541 0.931507
44 AR6 0.540541 0.931507
45 5FA 0.540541 0.931507
46 ADP VO4 0.53913 0.945205
47 VO4 ADP 0.53913 0.945205
48 AD9 0.535714 0.906667
49 SAP 0.535714 0.883117
50 AGS 0.535714 0.883117
51 WAQ 0.533333 0.896104
52 ABM 0.53271 0.905405
53 DLL 0.529412 0.972222
54 00A 0.529412 0.921053
55 ACQ 0.526316 0.906667
56 NJP 0.526316 0.959459
57 ANP 0.526316 0.906667
58 OAD 0.525 0.932432
59 ADX 0.522523 0.839506
60 5AL 0.521739 0.945205
61 A1R 0.521008 0.871795
62 9SN 0.520325 0.909091
63 A 0.518868 0.930556
64 AMP 0.518868 0.930556
65 50T 0.517857 0.893333
66 ATF 0.517241 0.894737
67 1ZZ 0.516393 0.851852
68 3OD 0.516393 0.932432
69 SON 0.513514 0.92
70 PRX 0.513274 0.881579
71 6YZ 0.512821 0.906667
72 SRP 0.512821 0.92
73 9X8 0.512397 0.883117
74 ADP BMA 0.512397 0.932432
75 3UK 0.512397 0.958904
76 MYR AMP 0.512195 0.851852
77 NAJ PZO 0.510949 0.909091
78 NMN 0.509434 0.875
79 A3R 0.508333 0.871795
80 B5V 0.508197 0.945946
81 AMP DBH 0.507937 0.906667
82 A22 0.504202 0.945205
83 ATP A A A 0.504 0.971831
84 B5M 0.504 0.933333
85 FA5 0.504 0.945946
86 8QN 0.5 0.945205
87 NAX 0.496183 0.886076
88 TYR AMP 0.496063 0.933333
89 PR8 0.495935 0.8625
90 AMO 0.495868 0.92
91 ADQ 0.495868 0.932432
92 4AD 0.495868 0.933333
93 PAJ 0.495868 0.873418
94 A12 0.495495 0.894737
95 AP2 0.495495 0.894737
96 AHZ 0.492308 0.851852
97 YAP 0.492063 0.933333
98 FYA 0.491935 0.918919
99 AHX 0.491803 0.884615
100 4UU 0.488372 0.933333
101 5SV 0.487603 0.8375
102 TAT 0.487179 0.894737
103 T99 0.487179 0.894737
104 APC 0.486957 0.894737
105 SRA 0.486239 0.881579
106 6V0 0.484848 0.909091
107 NAI 0.484848 0.921053
108 GTA 0.484615 0.898734
109 A A 0.483871 0.958333
110 LAD 0.483871 0.873418
111 AU1 0.482456 0.906667
112 F2R 0.481752 0.831325
113 OMR 0.481203 0.841463
114 TXE 0.481203 0.921053
115 AF3 ADP 3PG 0.481203 0.873418
116 LAQ 0.480916 0.851852
117 G3A 0.48062 0.909091
118 B5Y 0.480315 0.933333
119 NB8 0.48 0.884615
120 TXA 0.48 0.92
121 BIS 0.48 0.871795
122 ME8 0.48 0.851852
123 PTJ 0.48 0.884615
124 139 0.477941 0.886076
125 LPA AMP 0.477273 0.851852
126 AFH 0.476923 0.873418
127 AR6 AR6 0.476923 0.958333
128 G5P 0.476923 0.909091
129 ARG AMP 0.476923 0.841463
130 25L 0.47619 0.945205
131 NAJ PYZ 0.475524 0.864198
132 25A 0.47541 0.958333
133 9ZA 0.47541 0.896104
134 9ZD 0.47541 0.896104
135 DZD 0.47482 0.897436
136 TXD 0.473684 0.921053
137 4UV 0.472868 0.933333
138 TYM 0.470149 0.945946
139 RBY 0.470085 0.894737
140 ADV 0.470085 0.894737
141 4TA 0.467626 0.864198
142 48N 0.466165 0.884615
143 XAH 0.465116 0.851852
144 4UW 0.462687 0.897436
145 M24 0.461538 0.886076
146 80F 0.460993 0.853659
147 IOT 0.459854 0.821429
148 T5A 0.456522 0.853659
149 EAD 0.455782 0.886076
150 MAP 0.455285 0.883117
151 GA7 0.454545 0.894737
152 BT5 0.453901 0.821429
153 A4P 0.452555 0.833333
154 UP5 0.451852 0.933333
155 PAP 0.445378 0.917808
156 4TC 0.445255 0.909091
157 AP0 0.445255 0.884615
158 YLP 0.444444 0.831325
159 P1H 0.443709 0.864198
160 AOC 0.442478 0.810811
161 Z5A 0.439189 0.833333
162 LMS 0.4375 0.817073
163 2A5 0.436975 0.857143
164 A G 0.43662 0.921053
165 G A A A 0.43662 0.909091
166 COD 0.43662 0.802326
167 ADJ 0.435714 0.841463
168 YLB 0.434783 0.831325
169 YLC 0.434783 0.851852
170 U A G G 0.433566 0.921053
171 ATR 0.433333 0.90411
172 7MD 0.432836 0.851852
173 8X1 0.432 0.764045
174 G5A 0.429752 0.790698
175 PO4 PO4 A A A A PO4 0.429688 0.943662
176 TAD 0.42963 0.873418
177 5AS 0.42735 0.770115
178 BTX 0.426573 0.831325
179 YLA 0.425532 0.831325
180 DSZ 0.425197 0.790698
181 NCN 0.424779 0.805556
182 UPA 0.42446 0.921053
183 8PZ 0.424242 0.811765
184 VMS 0.424 0.8
185 54H 0.424 0.8
186 9K8 0.423077 0.744444
187 N0B 0.422819 0.853659
188 6AD 0.422764 0.85
189 AYB 0.422535 0.821429
190 7D3 0.422414 0.844156
191 YLY 0.421769 0.821429
192 TSB 0.420635 0.809524
193 ODP 0.41958 0.922078
194 AV2 0.419355 0.855263
195 FB0 0.419355 0.775281
196 A5A 0.419355 0.819277
197 NNR 0.419048 0.739726
198 A A A 0.418605 0.918919
199 U A 0.417808 0.946667
200 649 0.417266 0.775281
201 NMN AMP PO4 0.416667 0.933333
202 SSA 0.416 0.790698
203 P5A 0.415385 0.755556
204 LSS 0.414062 0.772727
205 A2R 0.412698 0.918919
206 52H 0.412698 0.790698
207 JB6 0.412214 0.896104
208 5N5 0.411215 0.783784
209 YSA 0.410448 0.811765
210 53H 0.409449 0.790698
211 5CA 0.409449 0.790698
212 ITT 0.408333 0.878378
213 7D4 0.408333 0.844156
214 NA7 0.407692 0.894737
215 LEU LMS 0.407692 0.784091
216 5CD 0.407407 0.794521
217 0WD 0.406897 0.909091
218 A3P 0.40678 0.930556
219 HFD 0.406504 0.883117
220 AVV 0.40625 0.860759
221 RAB 0.40566 0.808219
222 XYA 0.40566 0.808219
223 ADN 0.40566 0.808219
224 FDA 0.405063 0.823529
225 GSU 0.40458 0.790698
226 7MC 0.404255 0.831325
227 NSS 0.403101 0.811765
228 6FA 0.402516 0.853659
229 PPS 0.4 0.817073
230 NVA LMS 0.4 0.784091
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1FK8; Ligand: NAD; Similar sites found with APoc: 912
This union binding pocket(no: 1) in the query (biounit: 1fk8.bio1) has 26 residues
No: Leader PDB Ligand Sequence Similarity
1 6BKK 308 None
2 2WG9 OCA None
3 3KIH GDL None
4 4J7U YTZ 0.694444
5 4J7U NAP 0.694444
6 3KB6 NAD 0.77821
7 1OAA OAA 1.16732
8 5MDH NAD 1.16732
9 4MDH NAD 1.16732
10 4J4H 1J1 1.16732
11 4J4H NAI 1.16732
12 1TB4 PEJ 1.16732
13 6GKV SAH 1.16732
14 4JK3 NAD 1.16732
15 5JGL SAM 1.16732
16 1LC3 NAD 1.16732
17 2PHX MAN MAN 1.19048
18 2GN4 NDP 1.55642
19 2GN4 UD1 1.55642
20 3O0F AMP 1.55642
21 1M0S CIT 1.82648
22 1Z6Z NAP 1.94553
23 1X87 NAD 1.94553
24 3OND ADN 1.94553
25 3OND NAD 1.94553
26 1RJD SAM 1.94553
27 1YKJ FAD 1.94553
28 1YKJ PHB 1.94553
29 1RM0 D6P 1.94553
30 1RM0 NAI 1.94553
31 3MCT SAH 1.94553
32 1J0X NAD 1.94553
33 1TDF NAP 1.94553
34 6FDF SAH 1.94553
35 5W7K SAH 1.94553
36 2G5C NAD 1.94553
37 1LUA NAP 1.94553
38 1TDF FAD 1.94553
39 2JJQ SAH 1.94553
40 4EZD SEY 1.94553
41 3GF4 FAD 1.94553
42 2Q0L FAD 1.94553
43 3MAG SAH 1.94553
44 3JWH SAH 2.30415
45 3OFK SAH 2.31481
46 4ZGS NAD 2.33463
47 1HYE NAP 2.33463
48 9LDT NAD 2.33463
49 9LDB NAD 2.33463
50 1UWK URO 2.33463
51 1UWK NAD 2.33463
52 5OJL TXP 2.33463
53 5M67 3D1 2.33463
54 5M67 ADE 2.33463
55 5M67 NAD 2.33463
56 1EZ4 NAD 2.33463
57 1SC6 NAD 2.33463
58 5Z2F NAP 2.33463
59 5MIT FAD 2.33463
60 5MIT NAP 2.33463
61 4M52 FAD 2.33463
62 3G5S FAD 2.33463
63 1VKO NAD 2.33463
64 1V59 NAD 2.33463
65 2A92 NAI 2.33463
66 5TOW NAI 2.33463
67 5TOW ADN 2.33463
68 2QZZ EMF 2.33463
69 2QZZ NAP 2.33463
70 3L9W AMP 2.33463
71 1V8B NAD 2.33463
72 5XLX SAH 2.33463
73 5G3U ITW 2.33463
74 2WET FAD 2.33463
75 2GMH FAD 2.33463
76 4X7Y SAH 2.33463
77 5A04 BGC 2.33463
78 5A04 NDP 2.33463
79 5G3U FDA 2.33463
80 5N0J FAD 2.33463
81 1V59 FAD 2.33463
82 3GWZ SAH 2.33463
83 6F97 FAD 2.33463
84 1SAY PYR 2.33463
85 3RUV ANP 2.33463
86 2Q46 NAP 2.37154
87 1C3V NDP 2.44898
88 2XVM SAH 2.51256
89 4ZRN NAD 2.72374
90 5Y1G NAD 2.72374
91 5Y1G AKB 2.72374
92 2YY7 NAD 2.72374
93 3NJ4 NAD 2.72374
94 3NJ4 AFX 2.72374
95 4ZRN UPG 2.72374
96 5CAE SIN 2.72374
97 1LDN NAD 2.72374
98 5DF1 NAP 2.72374
99 5DF1 58X 2.72374
100 1NVM NAD 2.72374
101 2Q1S NAI 2.72374
102 5CAE COA 2.72374
103 5F8F SFG 2.72374
104 5Z20 NAI 2.72374
105 1P77 ATR 2.72374
106 3GCZ SAM 2.72374
107 4TXI FAD 2.72374
108 5JAQ NAI 2.72374
109 2VVM FAD 2.72374
110 3C1O NAP 2.72374
111 2VVL FAD 2.72374
112 1FP2 SAH 2.72374
113 6AIN FAD 2.72374
114 1H2B NAJ 2.72374
115 4JDR FAD 2.72374
116 1BXG NAD 2.72374
117 5U5G NAP 2.72374
118 3LGS SAH 2.72374
119 4AGS GSH 2.72374
120 1A99 PUT 2.72374
121 6GAR FAD 2.72374
122 5J60 FAD 2.72374
123 6FHO FAD 2.72374
124 2RI1 GLP 2.97872
125 1DQN IMU 3.04348
126 1ZGA SAH 3.08123
127 1Z45 NAD 3.11284
128 4TQG NDP 3.11284
129 5E9W SAH 3.11284
130 4ZVV NAD 3.11284
131 4ZVV GN0 3.11284
132 2UYQ SAM 3.11284
133 1PJS NAD 3.11284
134 4D79 ATP 3.11284
135 1Q0H NDP 3.11284
136 4RDH AMP 3.11284
137 1Q0H FOM 3.11284
138 1BW9 NAD 3.11284
139 1D1T NAD 3.11284
140 1GZ4 ATP 3.11284
141 1HKU NAD 3.11284
142 4RDI ATP 3.11284
143 1C1X NAD 3.11284
144 3G2O SAM 3.11284
145 6C4T NA7 3.11284
146 3ZNN FAD 3.11284
147 3ZNN 4WL 3.11284
148 1PS9 FAD 3.11284
149 2BRY FAD 3.11284
150 2Y6Q FAD 3.11284
151 5TC4 NAD 3.11284
152 6GAS FAD 3.11284
153 1LVW TYD 3.11284
154 1NPD NAD 3.11284
155 5AYV NAP 3.11284
156 2Y6Q I7T 3.11284
157 1RYD NDP 3.11284
158 5KOX RFP 3.11284
159 5KOX FAD 3.11284
160 5FJN BE2 3.11284
161 5FJN FAD 3.11284
162 3Q9T FAY 3.11284
163 5AYV KPL 3.11284
164 2IID FAD 3.11284
165 2IID PHE 3.11284
166 1H6C SIN 3.11284
167 1PS9 NAP 3.11284
168 1VI2 NAD 3.11284
169 1H6C NDP 3.11284
170 1TZD ADP 3.11284
171 1J5P NAD 3.16206
172 3F81 STT 3.27869
173 4G5H NAP 3.30579
174 4G5H UD7 3.30579
175 4QTU SAM 3.36538
176 3C3Y SAH 3.37553
177 5LOG SAH 3.43348
178 2CUL FAD 3.44828
179 4POO SAM 3.5
180 5L4L NAP 3.50195
181 2FR1 NDP 3.50195
182 3I6I NDP 3.50195
183 3GGO ENO 3.50195
184 3GGO NAI 3.50195
185 2HK9 ATR 3.50195
186 2IXB A2G 3.50195
187 5ME4 HP4 3.50195
188 5LD5 NAD 3.50195
189 1I36 NAP 3.50195
190 5L4L 7OX 3.50195
191 3VPH NAD 3.50195
192 6A3J NAI 3.50195
193 6A3J SOE 3.50195
194 2IXB NAD 3.50195
195 6C4N NAP 3.50195
196 3VPH OXM 3.50195
197 2CDU ADP 3.50195
198 1H5S TMP 3.50195
199 1H5R THM 3.50195
200 4PLT NAI 3.50195
201 1X7D ORN 3.50195
202 1TUU ADP 3.50195
203 1R6D NAD 3.50195
204 4PLT OXM 3.50195
205 2CDU FAD 3.50195
206 1KC7 PPR 3.50195
207 2CVQ NDP 3.50195
208 1ZGS XMM 3.50195
209 1X7D NAD 3.50195
210 1KYZ SAH 3.50195
211 3EF0 ALF 3.50195
212 1J49 NAD 3.50195
213 2HK9 NAP 3.50195
214 1MO9 FAD 3.50195
215 1COY FAD 3.50195
216 1COY AND 3.50195
217 2C7G ODP 3.50195
218 2DKH FAD 3.50195
219 1ZH8 NAP 3.50195
220 2C7G FAD 3.50195
221 1I2B USQ 3.50195
222 1I2B NAD 3.50195
223 1I2B UPG 3.50195
224 3GMB FAD 3.50195
225 1OC2 NAD 3.50195
226 1OC2 TDX 3.50195
227 1R6D DAU 3.50195
228 1NVT NAP 3.50195
229 1XDS SAM 3.50195
230 5MW4 5JU 3.50195
231 4DCM SAM 3.50195
232 2PT9 2MH 3.50195
233 2VT3 ATP 3.72093
234 4YMU ATP 3.75
235 3KIF GDL 3.77358
236 4WS6 WBU 3.78151
237 1WS1 BB2 3.84615
238 1RKX NAD 3.89105
239 5MSO NAP 3.89105
240 1ORR NAD 3.89105
241 1GY8 NAD 3.89105
242 1GV0 NAD 3.89105
243 4XB2 NDP 3.89105
244 1U1I NAD 3.89105
245 5Y77 FAD 3.89105
246 2WA2 SAM 3.89105
247 5JY6 NAD 3.89105
248 2B5W NAP 3.89105
249 1WP4 NDP 3.89105
250 5ERG SAM 3.89105
251 2JHP SAH 3.89105
252 5Y8L HUI 3.89105
253 5Y8L NAD 3.89105
254 4XB2 HSE 3.89105
255 1K3T BRZ 3.89105
256 3CTY FAD 3.89105
257 1D4D FAD 3.89105
258 4CJX NAP 3.89105
259 2IVD FAD 3.89105
260 2IZ1 ATR 3.89105
261 3AYI FAD 3.89105
262 3AYI HCI 3.89105
263 6FP4 E1T 3.89105
264 1TI7 NAP 3.89105
265 2Z3Y F2N 3.89105
266 3G89 SAM 4.01606
267 5T2Y 753 4.0404
268 1I7Q PYR 4.14508
269 1V6A TRE 4.28016
270 2EXX NAP 4.28016
271 4EUE NAI 4.28016
272 1A5Z NAD 4.28016
273 3OJF NDP 4.28016
274 1PL6 NAD 4.28016
275 1T26 GBD 4.28016
276 1T26 NAI 4.28016
277 2C29 NAP 4.28016
278 3OJF IMJ 4.28016
279 5UAO FAD 4.28016
280 3GU3 SAH 4.28016
281 1U3U NAD 4.28016
282 1U3U BNF 4.28016
283 4BHL ARG 4.28016
284 1CER NAD 4.28016
285 3TWO NDP 4.28016
286 2C29 DQH 4.28016
287 1F8G NAD 4.28016
288 6A0S NDP 4.28016
289 6A0S HSE 4.28016
290 4MOP 2H5 4.28016
291 1CF2 NAP 4.28016
292 5NA1 FAD 4.28016
293 5DOZ NDP 4.28016
294 6F3M NAD 4.28016
295 6F3N NAD 4.28016
296 6F3N ADN 4.28016
297 4DSG UDP 4.28016
298 4DSG FAD 4.28016
299 4BG4 ARG 4.28016
300 1N7G NDP 4.28016
301 2WPF WPF 4.28016
302 4XDY NAI 4.28016
303 5BVA FAD 4.28016
304 6E48 4OA 4.28016
305 2WPF FAD 4.28016
306 1N7G GDR 4.28016
307 4NTC FAD 4.28016
308 5W7R SAH 4.28016
309 1PL6 572 4.28016
310 2OBF SAH 4.28016
311 2OBF F83 4.28016
312 1RM4 NDP 4.28016
313 5ZZ6 ADP 4.32692
314 5ZZ6 NAD 4.32692
315 2BD0 NAP 4.5082
316 1HDR NAD 4.5082
317 5TWB FAD 4.65116
318 4U7W NDP 4.66926
319 6DNT NAD 4.66926
320 5Z75 NAD 4.66926
321 2JL1 NAP 4.66926
322 3B1F NAD 4.66926
323 3A06 NDP 4.66926
324 3A06 FOM 4.66926
325 3GFB NAD 4.66926
326 2ZJ1 ARJ 4.66926
327 5UAV NDP 4.66926
328 2ZJ1 NAD 4.66926
329 4R5M NAP 4.66926
330 2DFV NAD 4.66926
331 4XYB NDP 4.66926
332 5UAV TFB 4.66926
333 1HYH NAD 4.66926
334 5OCM NAP 4.66926
335 3V1Y NAD 4.66926
336 4GKV NAD 4.66926
337 4X9M FAD 4.66926
338 3LZW FAD 4.66926
339 2B4R NAD 4.66926
340 5ZYN FAD 4.66926
341 3AB1 FAD 4.66926
342 1GTE FAD 4.66926
343 1GAD NAD 4.66926
344 4R5M 4NO 4.66926
345 3E1T FAD 4.66926
346 3L4S NAD 4.66926
347 2B4R AES 4.66926
348 1Q9I FAD 4.66926
349 1Q9I TEO 4.66926
350 3L4S 3PG 4.66926
351 3LZW NAP 4.66926
352 4FZV SAM 4.66926
353 2ZXI FAD 4.66926
354 2HQM FAD 4.80167
355 3SQP FAD 4.81172
356 5OOH 9ZZ 4.85437
357 5OOH NAP 4.85437
358 1UXG FUM 4.85437
359 1UXG NAD 4.85437
360 5X2N ALA 4.88889
361 1EJ0 SAM 5
362 4YAC NAI 5.05837
363 3LU1 NAD 5.05837
364 4PVD NDP 5.05837
365 3H8V ATP 5.05837
366 5XWV NDP 5.05837
367 5XWV 8H6 5.05837
368 5ZI2 NAD 5.05837
369 5ZI2 ADP 5.05837
370 3CMC NAD 5.05837
371 1LDM NAD 5.05837
372 1E3I CXF 5.05837
373 1WDK NAD 5.05837
374 2VYN NAD 5.05837
375 2NAD NAD 5.05837
376 5UR0 NAD 5.05837
377 5X68 FAD 5.05837
378 3B20 NAD 5.05837
379 1DRV A3D 5.05837
380 1E5Q NDP 5.05837
381 5WP4 SAH 5.05837
382 1ZQ9 SAM 5.05837
383 2CDC XYP 5.05837
384 2CDC NAP 5.05837
385 3B1J NAD 5.05837
386 3CGD FAD 5.05837
387 2D2I NAP 5.05837
388 3CGD NAD 5.05837
389 3CGD COA 5.05837
390 3CGB FAD 5.05837
391 4AP3 FAD 5.05837
392 4AP3 NAP 5.05837
393 2JB2 PHE 5.05837
394 2JB2 FAD 5.05837
395 4OPC FDA 5.05837
396 1NAA 6FA 5.05837
397 1NAA ABL 5.05837
398 2CDC XYS 5.05837
399 3MB5 SAM 5.09804
400 1B8U NAD 5.16717
401 1B8U OAA 5.16717
402 5EES NAP 5.26316
403 1Y1P NMN AMP PO4 5.44747
404 2GZ3 NAP 5.44747
405 6CEP NAD 5.44747
406 6CEP OXM 5.44747
407 2GSD NAD 5.44747
408 5EW9 5VC 5.44747
409 5Z21 NAI 5.44747
410 2FZW NAD 5.44747
411 1FP1 SAH 5.44747
412 3LST SAH 5.44747
413 4E5N NAD 5.44747
414 4ZCC NAI 5.44747
415 4ZCC FAD 5.44747
416 1I8T FAD 5.44747
417 4RF7 ARG 5.44747
418 4D04 NAP 5.44747
419 4D04 FAD 5.44747
420 4N49 SAM 5.44747
421 3WV8 ATP 5.50459
422 2YVJ NAI 5.50459
423 2OOR NAD 5.74713
424 2HJR APR 5.79268
425 5L4S 6KX 5.83658
426 5L4S NAP 5.83658
427 5KKA 6V0 5.83658
428 6AA8 NAD 5.83658
429 2QRK AMP 5.83658
430 4LHD GLY 5.83658
431 3LCC SAH 5.83658
432 3WGT QSC 5.83658
433 3WGT FAD 5.83658
434 1H82 GZZ 5.83658
435 1RJW ETF 5.83658
436 1H82 FAD 5.83658
437 3BAZ NAP 5.83658
438 4MP8 NAD 5.83658
439 4MP8 MLI 5.83658
440 1C0I FAD 5.83658
441 1C0I BE2 5.83658
442 1CDO NAD 5.83658
443 2VTD LKM 5.83658
444 3T7S SAM 5.83658
445 1O0S NAI 5.83658
446 3H9E NAD 5.83658
447 1N1G BCP 5.83658
448 5MLR NAP 6.08273
449 5MLR GRQ 6.08273
450 5GT9 NAP 6.22568
451 4GLL NAD 6.22568
452 1ZBQ NAD 6.22568
453 1RPN NDP 6.22568
454 3ICS ADP 6.22568
455 3ICT ADP 6.22568
456 2VHW NAI 6.22568
457 4NEC SAH 6.22568
458 4J36 FAD 6.22568
459 1MUU NAD 6.22568
460 4J36 1HR 6.22568
461 4OM8 NAD 6.22568
462 1MV8 NAD 6.22568
463 5JE8 NAD 6.22568
464 2ZWA SAH 6.22568
465 1KOL NAD 6.22568
466 5OC1 FAD 6.22568
467 3OJO NAD 6.22568
468 4JNA FAD 6.22568
469 6D6Y SAH 6.22568
470 4RPL 3UC 6.22568
471 4RPL FAD 6.22568
472 4IDC 1XX 6.22568
473 4IDC NDP 6.22568
474 1GQ2 NAP 6.22568
475 1GPE FAD 6.22568
476 3NKS FAD 6.22568
477 4A59 AMP 6.22568
478 1RP0 AHZ 6.22568
479 4LWP SAH 6.22568
480 1BZL GCG 6.22568
481 5YU3 PRO 6.22568
482 5YU3 NAD 6.22568
483 2Q7V FAD 6.22568
484 1XHC FAD 6.22568
485 3ICS FAD 6.22568
486 1BZL FAD 6.22568
487 6C5B SAH 6.22568
488 2EB5 OXL 6.22568
489 3O5N BR0 6.25
490 5YAP NAI 6.57895
491 5YAP 8S0 6.57895
492 3KO8 NAD 6.61479
493 1GZ6 NAI 6.61479
494 4XQC 13D 6.61479
495 4XQC NAD 6.61479
496 5BJX NAD 6.61479
497 3H5N ATP 6.61479
498 5KVS NAP 6.61479
499 2EV9 SKM 6.61479
500 2EV9 NAP 6.61479
501 5BJX UDP 6.61479
502 1YB5 NAP 6.61479
503 2PV7 NAD 6.61479
504 1UDB NAD 6.61479
505 1UDB UFG 6.61479
506 5G6U TRP 6.61479
507 4YSX FAD 6.61479
508 1E1M FAD 6.61479
509 1E1M NAP 6.61479
510 4AUT FAD 6.61479
511 4YCA NDP 6.61479
512 5T9E NAP 6.61479
513 5U5N NAD 6.61479
514 5KOK SAH 6.61479
515 5O98 NAP 7.00389
516 6BWL NAD 7.00389
517 1BXK NAD 7.00389
518 3O9Z NAD 7.00389
519 5T9F TYR 7.00389
520 3O9Z AKG 7.00389
521 2F1K NAP 7.00389
522 5T9F NAP 7.00389
523 1YS4 NAP 7.00389
524 3OA2 NAD 7.00389
525 3WQQ IB3 7.00389
526 3WQQ NDP 7.00389
527 1P0F NAP 7.00389
528 4KP7 NAP 7.00389
529 3T31 DCQ 7.00389
530 3T31 FAD 7.00389
531 6BII NAP 7.00389
532 4KP7 1UQ 7.00389
533 4MO2 FDA 7.00389
534 1YJQ NAP 7.00389
535 4MO2 FAD 7.00389
536 1LLU NAD 7.00389
537 5BRT FAD 7.00389
538 5BRT CH9 7.00389
539 3UOY FAD 7.00389
540 3UOY NAP 7.00389
541 4M73 SAH 7.00389
542 4M73 M72 7.00389
543 3WLE NAD 7.00389
544 3UCL NAP 7.00389
545 6F7L FAD 7.00389
546 5CGE 51F 7.00389
547 5JWC FAD 7.00389
548 3UCL FAD 7.00389
549 3UCL CYH 7.00389
550 5EZ7 FAD 7.00389
551 3RJ5 NAD 7.08661
552 3BXO SAM 7.11297
553 3QV1 NAD 7.31707
554 1WVG APR 7.393
555 4PIV NDP 7.393
556 4OOE NDP 7.393
557 4OOE FOM 7.393
558 4E13 NAD 7.393
559 1KYQ NAD 7.393
560 4D3F NAP 7.393
561 4DPL NAP 7.393
562 2DBZ NAP 7.393
563 5AOV NAP 7.393
564 1JNR FAD 7.393
565 2O4C NAD 7.393
566 5N6C NAD 7.393
567 3TKY SAH 7.393
568 3WBF API 7.393
569 1YY5 FAD 7.393
570 2BKA NDP 7.43802
571 4K26 NDP 7.7821
572 4J1Q NDP 7.7821
573 4K26 SFF 7.7821
574 3WMX NAD 7.7821
575 1LTH NAD 7.7821
576 1GUZ NAD 7.7821
577 4L8V NAP 7.7821
578 1GR0 NAD 7.7821
579 4MIG G3F 7.7821
580 2AQJ TRP 7.7821
581 2AQJ FAD 7.7821
582 4PLG NAI 7.7821
583 4PLG OXM 7.7821
584 4KIB SAH 7.7821
585 3PLN U5P 7.7821
586 1Y8Q ATP 7.7821
587 1PZG A3D 7.7821
588 4W6Z 8ID 7.7821
589 2GCG NDP 7.7821
590 5FTW SAH 7.8125
591 4JLS 3ZE 7.89474
592 3AD8 FAD 8.08081
593 3AD8 PYC 8.08081
594 5O96 SAM 8.16327
595 1YQZ FAD 8.17121
596 3A4T SFG 8.17121
597 3ULK NDP 8.17121
598 5KMS NAD 8.17121
599 5X20 NAD 8.17121
600 5A1T NAI 8.56031
601 3O7W SAM 8.56031
602 5A1T OXM 8.56031
603 3FSY SCA 8.56031
604 4EIP FAD 8.56031
605 5H81 NAP 8.56031
606 5FI3 NAP 8.56031
607 1PN0 FAD 8.56031
608 1PN0 IPH 8.56031
609 1QZZ SAM 8.56031
610 1R37 NAD 8.64553
611 2WPB ZZI 8.88158
612 1TL2 NDG 8.8983
613 4YAG NAI 8.94942
614 1EK6 NAI 8.94942
615 3RFV NAI 8.94942
616 1EK6 UPG 8.94942
617 3RFV 15L 8.94942
618 5DN9 NAD 8.94942
619 5XNC MTA 8.94942
620 1GPJ CIT 8.94942
621 2NVK FAD 8.94942
622 2RAB NAD 8.94942
623 2RAB FAD 8.94942
624 4N14 WR7 8.94942
625 3QVP FAD 8.94942
626 4P8K 38C 8.94942
627 4P8K FAD 8.94942
628 5TUF FAD 8.94942
629 5E8J SAH 9.09091
630 5NUF NAD 9.33735
631 5NUE NAD 9.33735
632 1XSE NDP 9.33852
633 5IN4 6CK 9.33852
634 5IN4 GDP 9.33852
635 5IN4 NAP 9.33852
636 4Z0H NAD 9.33852
637 5O9F NAD 9.33852
638 5O9F 9ON 9.33852
639 5MZI FYK 9.33852
640 5MZI FAD 9.33852
641 5WP5 SAH 9.33852
642 1NYT NAP 9.33852
643 1EBF NAD 9.33852
644 6ECU SAH 9.33852
645 2DT5 NAD 9.47867
646 3HAD NAD 9.72763
647 1SOW NAD 9.72763
648 4RSL FAD 9.72763
649 5VN0 FAD 9.72763
650 2NU8 COA 9.72763
651 5VN0 NAI 9.72763
652 2GAG FAD 10.101
653 2GAG FOA 10.101
654 2GAG NAD 10.101
655 2Q1W NAD 10.1167
656 2C5A NAD 10.1167
657 2C5A GDC 10.1167
658 1DKU AP2 10.1167
659 1O6Z NAD 10.231
660 2GDZ NAD 10.5058
661 2JHF NAD 10.5058
662 5MPT SAH 10.5058
663 3SSO SAH 10.5058
664 5F5N NAD 10.8949
665 1V35 NAI 10.8949
666 2PZM NAD 10.8949
667 2PZM UDP 10.8949
668 5K0A FAD 10.8949
669 2QA1 FAD 10.8949
670 1FEC FAD 10.8949
671 5YB7 FAD 10.8949
672 5YB7 ORN 10.8949
673 5U8U FAD 10.8949
674 4CS9 AMP 11.1111
675 5X9D 80F 11.284
676 1KEW NAD 11.284
677 1KEW TYD 11.284
678 5BSH PRO 11.284
679 1XF1 CIT 11.284
680 2VDV SAM 11.3821
681 1LSS NAD 11.4286
682 3ORF NAD 11.5538
683 3ABI NAD 11.6732
684 5K4W NAI 11.6732
685 5K4W THR 11.6732
686 2XYQ SAH 11.6732
687 4RQU NAD 11.6732
688 1DLJ NAI 11.6732
689 4K5S FAD 11.6732
690 4K5S PM0 11.6732
691 1DLJ UGA 11.6732
692 5E4R NAP 11.6732
693 4HXY NDP 12.0623
694 4B7X NAP 12.0623
695 2PK3 A2R 12.4514
696 3AXB PRO 12.4514
697 3AXB FAD 12.4514
698 5J5Z FAD 12.4514
699 2HMT NAI 12.5
700 5WQP NAP 12.8205
701 5WQP NCA 12.8205
702 1E7S NAP 12.8405
703 2I3G NAP 12.8405
704 5THY SAH 13.2296
705 1VL0 NAI 13.6187
706 1HDG NAD 13.6187
707 5THZ SAH 13.6187
708 3LXD FAD 13.6187
709 6EL3 NAP 14.0078
710 2V6G NAP 14.0078
711 6BQ6 TER 14.0078
712 4BVA NDP 14.0078
713 5B4T NAD 14.3969
714 5B4T 3HR 14.3969
715 3LTW HLZ 14.3969
716 1DSS NAD 14.786
717 2PD4 DCN 14.9091
718 2PD4 NAD 14.9091
719 1VM6 NAD 14.9123
720 5YEC ATP 15.1751
721 4O1M NAD 15.1751
722 1D7O TCL 15.1751
723 1D7O NAD 15.1751
724 3CIF G3H 15.1751
725 3CIF NAD 15.1751
726 5ZEC NAP 15.5642
727 1E6E FAD 15.625
728 3OID NDP 15.9533
729 5XVH NAP 15.9533
730 5L95 AMP 16.25
731 3H4V DVP 16.3424
732 3H4V NAP 16.3424
733 5EPO NAP 16.3424
734 3CH6 311 16.3424
735 3CH6 NAP 16.3424
736 4D42 W0I 17.1206
737 4D42 NAP 17.1206
738 2Q2V NAD 17.2549
739 2EWM NAD 17.2691
740 3GEG NAD 17.4089
741 4OSP NAP 17.5097
742 3U4C NDP 17.5097
743 2WYV NAD 17.5097
744 1ZEM NAD 17.8988
745 1X1T NAD 17.8988
746 1MXH DHF 17.8988
747 3OIG NAD 17.8988
748 1MXH NAP 17.8988
749 4II2 ATP 17.8988
750 4XZ3 COA 17.8988
751 3ICC NAP 18.0392
752 3NUG NAD 18.2186
753 1W6U NAP 18.2879
754 1YXM ADE 18.2879
755 1JA9 NDP 18.2879
756 5CG1 NAD BBN 18.2879
757 4FC7 NAP 18.2879
758 4FC7 COA 18.2879
759 1QG6 NAD 18.2879
760 1QG6 TCL 18.2879
761 1SQF SAM 18.2879
762 5EIN NAP 18.5185
763 3SJ7 NDP 18.6508
764 1GEE NAD 18.677
765 3AY6 NAI 18.677
766 3AY6 BGC 18.677
767 3WXB NDP 19.0661
768 3O26 NDP 19.0661
769 4KWI NAP 19.0661
770 4KWI 1TJ 19.0661
771 5OJI NAP 19.0661
772 5OJI ISN 19.0661
773 2RH4 EMO 19.0661
774 4XYM COA 19.0661
775 3JQ7 NAP 19.4553
776 3JQB NAP 19.4553
777 5OVL NAP 19.4553
778 3JQA NAP 19.4553
779 5JDI NAP 19.4553
780 5K6A NAP 19.4553
781 4CM8 NAP 19.4553
782 4CM4 NAP 19.4553
783 3JQ8 NAP 19.4553
784 5JCJ NAP 19.4553
785 5JDC NAP 19.4553
786 3JQF NAP 19.4553
787 3BMO NAP 19.4553
788 4CM9 NAP 19.4553
789 3JQ9 NAP 19.4553
790 4CLO NAP 19.4553
791 3BMN NAP 19.4553
792 2WD7 NAP 19.4553
793 4CLR NAP 19.4553
794 3BMQ NAP 19.4553
795 3JQG NAP 19.4553
796 4CMI NAP 19.4553
797 5WUW NAP 19.4553
798 4CME NAP 19.4553
799 4O0L NDP 19.4553
800 4Q9N NAI 19.4553
801 2VZ0 D64 19.4553
802 2VZ0 NAP 19.4553
803 6ER9 FAD 19.4553
804 6ER9 NAP 19.4553
805 4YKG NAD 19.4553
806 4YKG FAD 19.4553
807 5OVK NDP 19.5312
808 4URF NAD 19.7581
809 1E3W NAD 19.8444
810 1E6W NAD 19.8444
811 1W8D NAP 19.8444
812 1W73 NAP 19.8444
813 3QWI NAP 19.8444
814 3QWI CUE 19.8444
815 1SB8 NAD 19.8444
816 1SB8 UD2 19.8444
817 5L3W GDP 19.8444
818 2CFC NAD 20
819 4RF2 NAP 20.2335
820 3A4V PYR 20.2335
821 3A4V NAD 20.2335
822 5L53 NAP 20.6226
823 4ITU NAI 20.6226
824 1G0N NDP 20.6226
825 1G0N PHH 20.6226
826 4ITU 1HS 20.6226
827 5Z2L NDP 20.8163
828 4CQM NAP 20.9016
829 3SJU NDP 21.0117
830 3VZS CAA 21.0117
831 1NFQ NAI 21.0117
832 5FFF NAP 21.0117
833 5FFF 5XC 21.0117
834 3VZS NAP 21.0117
835 1EDO NAP 21.3115
836 1ZK4 AC0 21.5139
837 1ZK4 NAP 21.5139
838 1UZN NAP 21.8623
839 5FEU NAP 22.179
840 1H9A NAP 22.179
841 1N5D NDP 22.5681
842 1AE1 NAP 22.9572
843 2X6T NAP 24.1245
844 1EQ2 NAP 24.1245
845 2DC1 NAD 24.1525
846 1A27 NAP 24.5136
847 3HB5 NAP 24.5136
848 3TN7 NJP 24.9027
849 2XVE FAD 24.9027
850 5G4L NDP 25.2918
851 5N2I NAP 26.7241
852 4OHU 2TK 27.6265
853 4OHU NAD 27.6265
854 1SNY NAP 30.7393
855 4R1S NAP 30.7393
856 2AE2 NAP 31.1284
857 2AE2 PTO 31.1284
858 1WMA NDP 31.5175
859 1WMA AB3 31.5175
860 2ZAT NAP 33.463
861 1VL8 NAP 33.8521
862 5I7S NAD 33.8521
863 5I7S E9P 33.8521
864 2JAP NDP 34.0081
865 4QED NAP 35.4839
866 5THQ NDP 37.7432
867 4Y9D NAI 37.7432
868 2BGM NAJ 37.7698
869 5YSS NAD 38.2812
870 4FN4 NAD 38.9764
871 3V1U NAD 39.2996
872 3A28 NAD 39.2996
873 4ZA2 NAD 39.5257
874 5EJ2 NAD 40.0778
875 3ZV6 NAD 40.4669
876 3ZV6 4HB 40.4669
877 1XG5 NAP 40.4669
878 6CI9 NAP 40.4669
879 2JAH NDP 40.8907
880 4NBU NAI 41.2
881 3RKR NAP 41.2451
882 1GEG NAD 41.4062
883 5O42 9JW 41.6058
884 5O42 BGC 41.6058
885 5O42 NAD 41.6058
886 1BDB NAD 41.6342
887 1NNU NAD 41.6667
888 1NNU TCT 41.6667
889 1H5Q NAP 43.0189
890 5GWT NAD 43.1907
891 5GWT SIN 43.1907
892 1XHL NDP 43.1907
893 2B4Q NAP 43.1907
894 2WSB NAD 43.3071
895 4NBT NAD 43.3333
896 6F9Q NAD 43.5798
897 3O03 NAP 43.5798
898 2AG5 NAD 43.9024
899 3AFN NAP 44.186
900 1PR9 NAP 44.2623
901 3D3W NAP 44.2623
902 1HDC CBO 44.4882
903 2DTX BMA 44.7471
904 1O5I NAD 44.9799
905 1U7T NAD 45.1362
906 1XKQ NDP 45.1362
907 1U7T TDT 45.1362
908 1Q7B NAP 45.4918
909 4NBW NAD 46.6926
910 1IY8 NAD 47.0817
911 5T2U NAP 47.1774
912 1UAY ADN 48.3471
Pocket No.: 2; Query (leader) PDB : 1FK8; Ligand: NAD; Similar sites found with APoc: 51
This union binding pocket(no: 2) in the query (biounit: 1fk8.bio1) has 27 residues
No: Leader PDB Ligand Sequence Similarity
1 3EGI ADP None
2 2PHU MAN MAN 1.19048
3 1Q8S MAN MMA 1.19048
4 1Q8V MAN MAN 1.19048
5 2EG5 SAH 1.94553
6 3QX9 ATP 2.17391
7 5BW4 SAM 2.33463
8 1G55 SAH 2.33463
9 5TH5 MET 2.33463
10 3GXO SAH 2.33463
11 1NE7 16G 2.33463
12 4K6B GLU 2.48447
13 1P19 IMP 2.71493
14 2HIM ASP 2.72374
15 5YJI 8WO 2.72374
16 5YJI SAH 2.72374
17 2VNO GAL GAL FUC 2.77778
18 4YUW 4JU 3.11284
19 4YUW S4M 3.11284
20 5J6Y GLC 3.19149
21 5J6Y BGC 3.19149
22 2I7C AAT 3.50195
23 4GK9 MAN BMA MAN MAN MAN 3.50195
24 1O5Q PYR 3.50195
25 2O07 MTA 3.50195
26 2O07 SPD 3.50195
27 2VUT NAD 3.89105
28 3LCV SAM 3.89105
29 2YX1 SFG 4.66926
30 2FGQ MLT 5.05837
31 4DE3 DN8 5.05837
32 5T8U LPA 5.44747
33 3HDY GDU 5.44747
34 3HDY FAD 5.44747
35 5FPE 3TR 5.83658
36 3MQ2 SAH 5.9633
37 5E58 CPZ 6.22568
38 5W7M SAH 6.22568
39 5MB4 NDG 7.00389
40 3BJE URA 7.00389
41 4HBM 0Y7 7.7821
42 2PXX SAH 8.83721
43 4C3Y FAD 8.94942
44 5JCA FAD 9.85915
45 5C2N NAG 12.5
46 4IXW IXW 13.3858
47 3KP6 SAL 16.5563
48 4ZU3 4SD 18.9427
49 3AI3 SOL 19.0661
50 4YRY FAD 22.179
51 4YRY NAD 22.179
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