-->
Receptor
PDB id Resolution Class Description Source Keywords
1FP1 1.82 Å EC: 2.-.-.- CRYSTAL STRUCTURE ANALYSIS OF CHALCONE O-METHYLTRANSFERASE MEDICAGO SATIVA PROTEIN-SUBSTRATE PROTEIN-PRODUCT COMPLEX TRANSFERASE
Ref.: STRUCTURES OF TWO NATURAL PRODUCT METHYLTRANSFERASE THE BASIS FOR SUBSTRATE SPECIFICITY IN PLANT O-METHYLTRANSFERASES. NAT.STRUCT.BIOL. V. 8 271 2001
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
HCC D:2000;
Valid;
none;
submit data
256.253 C15 H12 O4 c1cc(...
SAH D:1699;
Valid;
none;
submit data
384.411 C14 H20 N6 O5 S c1nc(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1FP1 1.82 Å EC: 2.-.-.- CRYSTAL STRUCTURE ANALYSIS OF CHALCONE O-METHYLTRANSFERASE MEDICAGO SATIVA PROTEIN-SUBSTRATE PROTEIN-PRODUCT COMPLEX TRANSFERASE
Ref.: STRUCTURES OF TWO NATURAL PRODUCT METHYLTRANSFERASE THE BASIS FOR SUBSTRATE SPECIFICITY IN PLANT O-METHYLTRANSFERASES. NAT.STRUCT.BIOL. V. 8 271 2001
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 269 families.
1 1FPQ - SAM C15 H22 N6 O5 S C[S@@+](CC....
2 1FP1 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 237 families.
1 1FPQ - SAM C15 H22 N6 O5 S C[S@@+](CC....
2 1FP1 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
50% Homology Family (15)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 187 families.
1 6C5B - SAH C14 H20 N6 O5 S c1nc(c2c(n....
2 5ICF - SAU C20 H14 N O4 C[n+]1cc2c....
3 5ICC - SAH C14 H20 N6 O5 S c1nc(c2c(n....
4 5ICE - 2H4 C16 H17 N O4 c1cc(c(cc1....
5 3P9K - SAH C14 H20 N6 O5 S c1nc(c2c(n....
6 3P9I - SAH C14 H20 N6 O5 S c1nc(c2c(n....
7 3P9C - SAH C14 H20 N6 O5 S c1nc(c2c(n....
8 1KYW - SAH C14 H20 N6 O5 S c1nc(c2c(n....
9 1ZHF - SAH C14 H20 N6 O5 S c1nc(c2c(n....
10 1ZGJ - SAH C14 H20 N6 O5 S c1nc(c2c(n....
11 1FP1 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
12 6CIG - SAH C14 H20 N6 O5 S c1nc(c2c(n....
13 4E70 Kd = 2.94 uM N7I C10 H12 O3 COc1cc(ccc....
14 4EVI - SAH C14 H20 N6 O5 S c1nc(c2c(n....
15 3TKY - SAH C14 H20 N6 O5 S c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: HCC; Similar ligands found: 8
No: Ligand ECFP6 Tc MDL keys Tc
1 HCC 1 1
2 BUN 0.653846 0.92
3 X8W 0.568627 1
4 IPJ 0.471698 0.695652
5 HC4 0.468085 0.666667
6 DOB 0.456522 0.833333
7 4EU 0.45098 0.956522
8 27M 0.425532 0.956522
Ligand no: 2; Ligand: SAH; Similar ligands found: 211
No: Ligand ECFP6 Tc MDL keys Tc
1 SAH 1 1
2 5X8 0.759494 0.969697
3 A7D 0.734177 0.926471
4 TT8 0.709302 0.970588
5 DSH 0.692308 0.914286
6 SXZ 0.692308 0.916667
7 DTA 0.666667 0.857143
8 3DH 0.662338 0.869565
9 S8M 0.655556 0.901408
10 SFG 0.635294 0.954545
11 SA8 0.62069 0.915493
12 EEM 0.617977 0.890411
13 MTA 0.615385 0.869565
14 SAI 0.613636 0.955882
15 S7M 0.586957 0.916667
16 36A 0.586538 0.90411
17 K15 0.583333 0.878378
18 ADN 0.573333 0.84058
19 RAB 0.573333 0.84058
20 XYA 0.573333 0.84058
21 62X 0.572917 0.855263
22 5CD 0.571429 0.852941
23 0UM 0.5625 0.876712
24 5N5 0.558442 0.84058
25 A4D 0.551282 0.867647
26 SAM 0.537634 0.916667
27 SMM 0.536842 0.88
28 SSA 0.536842 0.712644
29 KB1 0.534653 0.902778
30 A5D 0.532609 0.857143
31 SIB 0.53125 0.928571
32 EP4 0.530864 0.819444
33 DSZ 0.530612 0.732558
34 GSU 0.53 0.752941
35 A 0.529412 0.763158
36 LMS 0.529412 0.694118
37 AMP 0.529412 0.763158
38 5CA 0.525773 0.712644
39 ME8 0.524752 0.8125
40 M2T 0.52439 0.821918
41 6RE 0.523256 0.824324
42 GJV 0.522727 0.813333
43 AAT 0.515789 0.863014
44 LSS 0.515152 0.696629
45 KAA 0.514852 0.727273
46 J7C 0.511364 0.835616
47 A5A 0.510417 0.697674
48 SON 0.505495 0.805195
49 SRP 0.505155 0.805195
50 F0P 0.504505 0.915493
51 54H 0.5 0.681818
52 VMS 0.5 0.681818
53 ADX 0.5 0.694118
54 CA0 0.5 0.769231
55 AMO 0.5 0.805195
56 5AL 0.5 0.779221
57 KH3 0.5 0.866667
58 NVA LMS 0.49505 0.707865
59 AHX 0.49505 0.753086
60 TSB 0.494949 0.689655
61 53H 0.494949 0.674157
62 G5A 0.494737 0.712644
63 ABM 0.494382 0.74359
64 A2D 0.494382 0.74359
65 ZAS 0.494253 0.808219
66 A6D 0.490196 0.759494
67 8QN 0.49 0.779221
68 GEK 0.49 0.956522
69 GAP 0.489583 0.769231
70 AN2 0.48913 0.734177
71 A3S 0.48913 0.884058
72 S4M 0.488889 0.831169
73 SRA 0.488636 0.746835
74 LAD 0.485437 0.810127
75 52H 0.484848 0.674157
76 A12 0.483516 0.759494
77 BA3 0.483516 0.74359
78 AP2 0.483516 0.759494
79 NEC 0.483146 0.788732
80 AOC 0.483146 0.842857
81 Y3J 0.481481 0.768116
82 VRT 0.479167 0.861111
83 50T 0.478723 0.734177
84 B4P 0.478261 0.74359
85 ADP 0.478261 0.74359
86 5AS 0.478261 0.655556
87 AP5 0.478261 0.74359
88 A3N 0.477778 0.830986
89 YSA 0.476636 0.712644
90 XAH 0.476636 0.768293
91 0XU 0.473684 0.897059
92 AT4 0.473118 0.7375
93 WAQ 0.471154 0.807692
94 NSS 0.470588 0.712644
95 5AD 0.468354 0.791045
96 AU1 0.468085 0.725
97 M33 0.468085 0.734177
98 MAO 0.467391 0.797468
99 TXA 0.466667 0.759494
100 NB8 0.466667 0.775
101 A3G 0.466667 0.871429
102 3AM 0.465909 0.727273
103 DAL AMP 0.465347 0.779221
104 8X1 0.465347 0.707865
105 A3T 0.463158 0.842857
106 ATP 0.463158 0.74359
107 HEJ 0.463158 0.74359
108 ACP 0.463158 0.746835
109 7D7 0.4625 0.785714
110 LEU LMS 0.461538 0.688889
111 9ZA 0.460784 0.740741
112 9ZD 0.460784 0.740741
113 5FA 0.458333 0.74359
114 AQP 0.458333 0.74359
115 AR6 0.458333 0.766234
116 APC 0.458333 0.759494
117 APR 0.458333 0.766234
118 PRX 0.458333 0.746835
119 F2R 0.457627 0.75
120 IOT 0.456897 0.761905
121 4AD 0.456311 0.794872
122 PAJ 0.456311 0.722892
123 WSA 0.45614 0.72093
124 YAP 0.453704 0.794872
125 8PZ 0.453704 0.712644
126 FA5 0.453704 0.805195
127 ADP PO3 0.453608 0.763158
128 ADV 0.453608 0.782051
129 NVA 2AD 0.453608 0.849315
130 SAP 0.453608 0.728395
131 AGS 0.453608 0.728395
132 RBY 0.453608 0.782051
133 AD9 0.453608 0.725
134 PTJ 0.45283 0.731707
135 MHZ 0.452632 0.797468
136 00A 0.451923 0.740741
137 A3P 0.451613 0.74026
138 YLP 0.451327 0.771084
139 7MD 0.45045 0.768293
140 ALF ADP 0.45 0.707317
141 ADP ALF 0.45 0.707317
142 2VA 0.447917 0.819444
143 OOB 0.446602 0.779221
144 ANP 0.444444 0.725
145 T99 0.444444 0.7375
146 ACQ 0.444444 0.746835
147 TAT 0.444444 0.7375
148 P5A 0.443396 0.719101
149 7D5 0.443182 0.708861
150 A1R 0.442308 0.7625
151 YLC 0.439655 0.790123
152 2AM 0.438202 0.717949
153 DLL 0.438095 0.779221
154 ARG AMP 0.4375 0.759036
155 A22 0.436893 0.734177
156 D3Y 0.436893 0.859155
157 ATF 0.435644 0.716049
158 MYR AMP 0.435185 0.746988
159 80F 0.434426 0.75
160 SO8 0.434343 0.808219
161 OAD 0.433962 0.769231
162 3UK 0.433962 0.769231
163 TAD 0.433628 0.765432
164 25A 0.432692 0.74359
165 6YZ 0.431373 0.746835
166 VO4 ADP 0.431373 0.734177
167 ADP VO4 0.431373 0.734177
168 9SN 0.431193 0.731707
169 TYM 0.431034 0.805195
170 B5V 0.429907 0.759494
171 PR8 0.429907 0.8
172 ADQ 0.428571 0.746835
173 YLB 0.42735 0.771084
174 9K8 0.425926 0.67033
175 1ZZ 0.425926 0.746988
176 FYA 0.425926 0.779221
177 3OD 0.425926 0.769231
178 PPS 0.425743 0.674419
179 MAP 0.423077 0.707317
180 A2P 0.421053 0.727273
181 4YB 0.421053 0.735632
182 9X8 0.420561 0.75
183 ADP BMA 0.420561 0.746835
184 TYR AMP 0.419643 0.794872
185 5SV 0.419048 0.731707
186 3NZ 0.416667 0.824324
187 YLA 0.416667 0.771084
188 8Q2 0.415254 0.688889
189 A3R 0.415094 0.7625
190 B5Y 0.414414 0.75
191 B5M 0.414414 0.75
192 48N 0.413793 0.753086
193 LPA AMP 0.413793 0.768293
194 AYB 0.413223 0.761905
195 ACK 0.413043 0.710526
196 QQY 0.413043 0.696203
197 BIS 0.412844 0.719512
198 JB6 0.412844 0.7625
199 PAP 0.41 0.730769
200 DQV 0.408696 0.75641
201 OVE 0.408602 0.7125
202 AMP DBH 0.40708 0.746835
203 4UV 0.40708 0.75
204 3AD 0.406977 0.852941
205 AF3 ADP 3PG 0.40678 0.743902
206 OMR 0.40678 0.738095
207 LAQ 0.405172 0.768293
208 A A 0.40367 0.74359
209 7C5 0.403509 0.789474
210 7MC 0.403361 0.75
211 4UU 0.4 0.75
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1FP1; Ligand: HCC; Similar sites found with APoc: 73
This union binding pocket(no: 1) in the query (biounit: 1fp1.bio1) has 21 residues
No: Leader PDB Ligand Sequence Similarity
1 4WG0 CHD None
2 4DW4 U5P None
3 3BJC WAN 1.34409
4 2HFK E4H 1.5674
5 1TV5 N8E 1.6129
6 1NHZ 486 2.14286
7 3VRV YSD 2.21402
8 5HCN DAO 2.29885
9 5U9J GER 2.36686
10 3RS8 ALA TRP LEU PHE GLU ALA 2.41935
11 3KP6 SAL 2.64901
12 2OZ5 7XY 2.7027
13 3MG9 GHP 3MY 3FG GHP GHP OMY 3FG 2.72109
14 6CB2 OLC 2.73038
15 4MGA 27L 2.7451
16 4TV1 36M 2.78884
17 1QFT HSM 2.85714
18 5U97 PIT 2.95699
19 2Q8G AZX 2.95699
20 5AZC PGT 3.33333
21 1A05 IPM 3.35196
22 2BCG GER 3.39806
23 6MVU K4V 3.49462
24 4X8D AVI 3.76344
25 1YOK P6L 3.90625
26 2YLD CMO 3.93701
27 6GKV F2W 3.9886
28 5C1M OLC 4
29 4UBS DIF 4.03226
30 3N29 GOL 4.03226
31 1J78 VDY 4.03226
32 4WGF HX2 4.39024
33 5XVG 8FX 4.43686
34 3PMA SCR 4.6332
35 5LX9 OLB 4.92958
36 1JGS SAL 5.07246
37 1OW4 2AN 5.42636
38 1SZ0 M6P 5.64516
39 5OSW DIU 5.91398
40 4YC9 4C1 5.97826
41 1AUA BOG 6.08108
42 5W7B MYR 6.1828
43 3RLF MAL 6.1828
44 1ZED PNP 6.45161
45 1MID LAP 6.59341
46 3KYQ DPV 7.03518
47 3CHT 4NB 7.44048
48 5E7V M7E 7.66667
49 3WFD AXO 8.87097
50 1Y4Z PCI 8.87097
51 2VWA PTY 9.90099
52 5C0C ARG GLN PHE GLY PRO ASP TRP ILE VAL ALA 10
53 5JZI LYS LEU VAL ALA LEU GLY ILE ASN ALA VAL 10
54 5WL1 CUY 10.101
55 5WL1 D3D 10.101
56 5C9J DAO 10.101
57 1IYB 5GP 11.5385
58 5FPN KYD 11.828
59 1XMY ROL 12.0968
60 1UUY PPI 12.5749
61 5FH7 5XL 12.9032
62 1MT1 AG2 13.4615
63 3G58 988 13.9785
64 4YSX E23 14.3617
65 6BJ3 ILE PRO LEU THR GLU GLU ALA GLU LEU 15.7025
66 5ZCO CHD 21.1009
67 5Z84 CHD 21.1009
68 3SCM LGN 24.2424
69 3QUZ QUV 24.2424
70 3GXO MQA 36.0434
71 5EEH SAH 40.0538
72 5EEH P9P 40.0538
73 5W7R 9Z7 43.5484
Pocket No.: 2; Query (leader) PDB : 1FP1; Ligand: HCC; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 1fp1.bio1) has 21 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 1FP1; Ligand: SAH; Similar sites found with APoc: 687
This union binding pocket(no: 3) in the query (biounit: 1fp1.bio1) has 19 residues
No: Leader PDB Ligand Sequence Similarity
1 2JAH NDP None
2 2JAP NDP None
3 3KIF GDL None
4 2AQJ FAD 1.07527
5 2AQJ TRP 1.07527
6 3A28 NAD 1.16279
7 4ZA2 NAD 1.18577
8 2VDV SAM 1.21951
9 5JCM ISD 1.34409
10 5JCM NAD 1.34409
11 5JCM FAD 1.34409
12 3UCL FAD 1.34409
13 3UCL CYH 1.34409
14 1BC5 SAH 1.48699
15 1RJD SAM 1.49701
16 3FZG SAM 1.5
17 4ZRN NAD 1.60256
18 4ZRN UPG 1.60256
19 2EG5 SAH 1.6129
20 1X87 NAD 1.6129
21 2FR1 NDP 1.6129
22 2C5A GDC 1.6129
23 2C5A NAD 1.6129
24 5KOX FAD 1.6129
25 5KOX RFP 1.6129
26 2DKH FAD 1.6129
27 2DKH 3HB 1.6129
28 4G5H UD7 1.65289
29 4G5H NAP 1.65289
30 1RKX NAD 1.68067
31 1XSE NDP 1.69492
32 3H8V ATP 1.71233
33 5WUW NAP 1.74216
34 5TWB FAD 1.74419
35 1RPN NDP 1.79104
36 4MDH NAD 1.79641
37 5MDH NAD 1.8018
38 5K4W NAI 1.86916
39 5K4W THR 1.86916
40 3PT9 SAH 1.88172
41 1GY8 NAD 1.88172
42 1BZL GCG 1.88172
43 1BZL FAD 1.88172
44 2C31 ADP 1.88172
45 2C31 TZD 1.88172
46 4MIG G3F 1.88172
47 2ZXI FAD 1.88172
48 1E1M NAP 1.88172
49 1E1M FAD 1.88172
50 3E1T FAD 1.88172
51 5TTJ FAD 1.88172
52 4IV9 FAD 1.88172
53 4XQC 13D 1.88172
54 4XQC NAD 1.88172
55 5XNC MTA 1.88679
56 4MO2 FAD 1.90217
57 4MO2 FDA 1.90217
58 1KEW NAD 1.93906
59 3WMX NAD 1.95531
60 4FN4 NAD 1.9685
61 3GRU AMP 2.0339
62 1UDB UFG 2.07101
63 1UDB NAD 2.07101
64 4CS9 AMP 2.1164
65 5AEW BNL 2.12766
66 5Y1G NAD 2.13415
67 5Y1G AKB 2.13415
68 5Z75 NAD 2.14067
69 2EJU SAH 2.15054
70 3L9W AMP 2.15054
71 3L9W GSH 2.15054
72 1RM0 NAI 2.15054
73 1RM0 D6P 2.15054
74 3GD4 FAD 2.15054
75 3GD4 NAD 2.15054
76 2Z3Y F2N 2.15054
77 5FWA J7C 2.15054
78 4M52 FAD 2.15054
79 4M52 M52 2.15054
80 2RAB NAD 2.15054
81 1H9A NAP 2.15054
82 2IID FAD 2.15054
83 2IID PHE 2.15054
84 4MOP 2H5 2.15054
85 1Q1R FAD 2.15054
86 2A8X FAD 2.15054
87 2JB2 PHE 2.15054
88 2JB2 FAD 2.15054
89 2RAB FAD 2.15054
90 5DF1 58X 2.17391
91 5DF1 NAP 2.17391
92 1I8T FAD 2.17984
93 4O0L NDP 2.18182
94 2V6G NAP 2.1978
95 4RF2 NAP 2.20588
96 1FWV SGA MAG FUC 2.23881
97 2DTX BMA 2.27273
98 2EXX NAP 2.28758
99 2P41 SAH 2.29508
100 3TKA SAM 2.30548
101 1W73 NAP 2.31788
102 1W8D NAP 2.31788
103 1W6U NAP 2.31788
104 2Q2V NAD 2.35294
105 6B92 SAH 2.38095
106 4GQB 0XU 2.41935
107 4X60 SFG 2.41935
108 4X60 3XV 2.41935
109 3TLJ SAH 2.41935
110 5FA5 MTA 2.41935
111 5ERG SAM 2.41935
112 3LAD FAD 2.41935
113 5T2U NAP 2.41935
114 1YY5 FAD 2.41935
115 1U8X NAD 2.41935
116 2PZM UDP 2.42424
117 2PZM NAD 2.42424
118 1NJR XYL 2.46479
119 1UAY ADN 2.47934
120 4FC7 COA 2.52708
121 4FC7 NAP 2.52708
122 3EVG SAH 2.54545
123 4X7Y SAH 2.55474
124 1OC2 TDX 2.58621
125 1OC2 NAD 2.58621
126 3CBG SAH 2.58621
127 4ITU NAI 2.60223
128 4ITU 1HS 2.60223
129 5CUQ NSC 2.62172
130 4EUE NAI 2.63158
131 2YX1 SFG 2.67857
132 5THY SAH 2.68817
133 3C6K SPD 2.68817
134 5WGR FAD 2.68817
135 1FEC FAD 2.68817
136 3C6K MTA 2.68817
137 3VSE SAH 2.68817
138 4EIP FAD 2.68817
139 1PN0 IPH 2.68817
140 1PN0 FAD 2.68817
141 5BRT CH9 2.68817
142 5BRT FAD 2.68817
143 5NMX FAD 2.68817
144 2NVK FAD 2.68817
145 4KGD TDP 2.68817
146 4KGD FAD 2.68817
147 5NMX NAP 2.68817
148 4K5S PM0 2.68817
149 3K7M FAD 2.68817
150 2CDU FAD 2.68817
151 4K5S FAD 2.68817
152 1E5Q NDP 2.68817
153 1PJS NAD 2.68817
154 1X1T NAD 2.69231
155 4NBW NAD 2.72374
156 1XHC FAD 2.7248
157 3ICC NAP 2.7451
158 2Q7V FAD 2.76923
159 4A59 AMP 2.78232
160 2CFC NAD 2.8
161 1GZ6 NAI 2.82132
162 5W7M SAH 2.88462
163 3I6I NDP 2.89017
164 2Q0L FAD 2.89389
165 1G55 SAH 2.91545
166 3MAG SAH 2.9316
167 3ELW SAM 2.95699
168 3ELW GP3 2.95699
169 2JJQ SAH 2.95699
170 1V5F FAD 2.95699
171 1V5F TPP 2.95699
172 1GPE FAD 2.95699
173 2NPX FAD 2.95699
174 2NPX NAD 2.95699
175 3AYI FAD 2.95699
176 6FHO FAD 2.95699
177 3AYI HCI 2.95699
178 4HXY NDP 2.96804
179 2PX8 SAH 2.97398
180 4GKV NAD 2.97619
181 3A25 SAM 2.99003
182 1VL8 NAP 2.99625
183 4POO SAM 3
184 5BJX UDP 3.00546
185 5BJX NAD 3.00546
186 2BZG SAH 3.01724
187 3MCT SAH 3.0303
188 2ZIF SAM 3.0303
189 3AB1 FAD 3.05556
190 1VM6 NAD 3.07018
191 2PWY SAH 3.10078
192 2OBF F83 3.11419
193 2OBF SAH 3.11419
194 5F7J ADE 3.125
195 5E8J SAH 3.20513
196 5E9W SAH 3.20513
197 1XKQ NDP 3.21429
198 2EFJ SAH 3.22581
199 5MPT SAH 3.22581
200 3HDY GDU 3.22581
201 3HDY FDA 3.22581
202 2WPF FAD 3.22581
203 3HDY FAD 3.22581
204 2WPF WPF 3.22581
205 2Q28 ADP 3.22581
206 4J36 1HR 3.22581
207 4J36 FAD 3.22581
208 5XWV 8H6 3.22581
209 5XWV NDP 3.22581
210 3ICT FAD 3.22581
211 3WQQ NDP 3.22581
212 3WQQ IB3 3.22581
213 3ICR FAD 3.22581
214 3ICS FAD 3.22581
215 5EJ2 NAD 3.24675
216 3ABI NAD 3.28767
217 4YUW 4JU 3.28947
218 4YUW S4M 3.28947
219 1AE1 NAP 3.2967
220 5HJM MTA 3.40909
221 1DUG GSH 3.4188
222 4KWI 1TJ 3.42205
223 4KWI NAP 3.42205
224 2CUL FAD 3.44828
225 2AE2 NAP 3.46154
226 2AE2 PTO 3.46154
227 3X0D SAH 3.49462
228 3GDN FAD 3.49462
229 3GDN HBX 3.49462
230 1E3I CXF 3.49462
231 4B63 NAP 3.49462
232 4B63 FAD 3.49462
233 4B63 ORN 3.49462
234 4YNU FAD 3.49462
235 4YNU LGC 3.49462
236 3CH6 311 3.4965
237 3CH6 NAP 3.4965
238 1LLU NAD 3.50877
239 1GEG NAD 3.51562
240 5GWX SAR 3.52113
241 5GWX SAM 3.52113
242 1NV8 SAM 3.52113
243 1NV8 MEQ 3.52113
244 5KKA 6V0 3.52564
245 3VYW SAM 3.57143
246 3EVF GTA 3.61011
247 3EVF SAH 3.61011
248 2WPB ZZI 3.61842
249 2WA2 SAM 3.62319
250 1YXM ADE 3.63036
251 5K0A FAD 3.63636
252 6BWL NAD 3.65854
253 2BD0 NAP 3.68852
254 1JQ3 AAT 3.71622
255 1NW5 SAM 3.76176
256 4RPL 3UC 3.76344
257 4RPL FAD 3.76344
258 3EYA FAD 3.76344
259 2IVD FAD 3.76344
260 1VKO NAD 3.76344
261 2HQM FAD 3.76344
262 2IV2 2MD 3.76344
263 2IV2 MGD 3.76344
264 2FK8 SAM 3.77358
265 4M38 SAH 3.79009
266 4M37 SAH 3.79009
267 3QJ4 FAD 3.80117
268 2A14 SAH 3.80228
269 3H4V NAP 3.81944
270 3H4V DVP 3.81944
271 1U7T TDT 3.83142
272 1E3W NAD 3.83142
273 1U7T NAD 3.83142
274 1RJW ETF 3.83481
275 1E6W NAD 3.84615
276 6CI9 NAP 3.861
277 5YJI SAH 3.87324
278 5YJI 8WO 3.87324
279 3AFN NAP 3.87597
280 5OOH NAP 3.8835
281 5OOH 9ZZ 3.8835
282 1PNO NAP 3.88889
283 5LW0 AR6 3.8961
284 1WVG APR 3.89972
285 1H2B NAJ 3.89972
286 1I1N SAH 3.9823
287 4K26 SFF 3.98551
288 4K26 NDP 3.98551
289 6GKV SAH 3.9886
290 3A4T SFG 4.0146
291 1EK6 UPG 4.02299
292 1EK6 NAI 4.02299
293 4C4A SAH 4.03226
294 6DEN G8A 4.03226
295 6DEN FAD 4.03226
296 6DEN TP9 4.03226
297 1YQZ FAD 4.03226
298 1O5I NAD 4.03226
299 3X01 AMP 4.03226
300 4EMI NAD 4.03226
301 4J1Q NDP 4.03226
302 4EMI FAD 4.03226
303 4IEE AGS 4.03226
304 4BUZ OCZ 4.06504
305 4BUZ OAD 4.06504
306 4BUZ NAD 4.06504
307 1QAN SAH 4.09836
308 4XUC SAM 4.12844
309 4XUC 43G 4.12844
310 3GDH SAH 4.14938
311 2UYQ SAM 4.19355
312 2Q1W NAD 4.2042
313 5NUF NAD 4.21687
314 5OJI NAP 4.23077
315 5OJI ISN 4.23077
316 5WP5 SAH 4.30108
317 5MLR GRQ 4.30108
318 5MLR NAP 4.30108
319 4RSL FAD 4.30108
320 3V1U NAD 4.30108
321 4DSG FAD 4.30108
322 4DSG UDP 4.30108
323 4BJZ FAD 4.30108
324 4BJZ P3A 4.30108
325 5BUK FAD 4.30108
326 3S5W FAD 4.30108
327 3NTA FAD 4.30108
328 1U1I NAD 4.30108
329 5EZ7 FAD 4.30108
330 2YG3 FAD 4.30108
331 5GWT SIN 4.31655
332 5GWT NAD 4.31655
333 1BDB NAD 4.33213
334 2RH4 EMO 4.33213
335 1RLZ NAD 4.33604
336 4J56 FAD 4.38596
337 3A27 SAM 4.41176
338 3G89 SAM 4.41767
339 4URF NAD 4.43548
340 3GEG NAD 4.45344
341 4FZV SAM 4.45682
342 5W7K SAH 4.48718
343 6BQ6 TER 4.53172
344 3SSO SAH 4.56989
345 6EL3 NAP 4.56989
346 4TQK NAG 4.56989
347 2GV8 FAD 4.56989
348 1VQW FAD 4.56989
349 2GVC FAD 4.56989
350 6H3O FAD 4.56989
351 6GAR FAD 4.58453
352 2O07 SPD 4.60526
353 2O07 MTA 4.60526
354 3OFK SAH 4.62963
355 4OBW SAM 4.66926
356 5FTW SAH 4.6875
357 2B4Q NAP 4.71014
358 2WSB NAD 4.72441
359 2OG2 MLI 4.73538
360 1R6D NAD 4.74777
361 1R6D DAU 4.74777
362 3O7W SAM 4.7619
363 3SBZ MLI 4.7619
364 5THQ NDP 4.77941
365 5MW4 5JU 4.79042
366 6FDF SAH 4.79042
367 2AOT SAH 4.79452
368 1JQD HSM 4.79452
369 1JQD SAH 4.79452
370 3Q87 SAM 4.8
371 3O03 NAP 4.811
372 2EWM NAD 4.81928
373 5KOK SAH 4.83871
374 5KOK S9T 4.83871
375 5KOK R9T 4.83871
376 4N49 SAM 4.83871
377 1I2B NAD 4.83871
378 1I2B UPG 4.83871
379 1I2B USQ 4.83871
380 4DMG SAM 4.83871
381 3S1S SAH 4.83871
382 5U8U FAD 4.83871
383 4U7W NDP 4.83871
384 3NTD FAD 4.83871
385 3GF4 FAD 4.83871
386 4Z24 FAD 4.83871
387 1RSG FAD 4.83871
388 1QO8 FAD 4.83871
389 3NT6 FAD 4.83871
390 4YAG NAI 4.84429
391 3NUG NAD 4.8583
392 1IY8 NAD 4.86891
393 5ZW3 SAH 4.88889
394 1ZBQ NAD 4.89297
395 1WG8 SAM 4.91228
396 1EDO NAP 4.91803
397 4L2I FAD 4.94297
398 1ZEM NAD 4.96183
399 1N2X SAM 4.98339
400 1G60 SAM 5
401 1Z3C SA8 5.03356
402 3OID NDP 5.03876
403 3AD8 NAD 5.05051
404 5OVK NDP 5.07812
405 1EFV FAD 5.09804
406 1EFV AMP 5.09804
407 3LCC SAH 5.10638
408 3QOX SAH 5.10753
409 5KMS FAD 5.10753
410 1U2Z SAH 5.10753
411 1SB8 UD2 5.11364
412 1SB8 NAD 5.11364
413 3KO8 NAD 5.12821
414 1WY7 SAH 5.31401
415 1PR9 NAP 5.32787
416 3D3W NAP 5.32787
417 3A4V NAD 5.36278
418 3A4V PYR 5.36278
419 4ZNO SUC 5.37313
420 5BVA FAD 5.37634
421 1Z45 NAD 5.37634
422 4D7E FAD 5.37634
423 3DUW SAH 5.38117
424 1FK8 NAD 5.44747
425 3VC1 GST 5.44872
426 3VC1 SAH 5.44872
427 1R37 NAD 5.4755
428 4EMJ FAD 5.60748
429 5DM1 5D7 5.61798
430 5DM1 SAH 5.61798
431 3RFV NAI 5.61798
432 3B9Q MLI 5.62914
433 5YRL GLC GLC 5.6338
434 5FUB SAH 5.63798
435 5WP4 SAH 5.64516
436 5JAQ NAI 5.64516
437 3NDJ JHZ 5.64516
438 3NDJ SAH 5.64516
439 2WET FAD 5.64516
440 1GET FAD 5.64516
441 1GET NAP 5.64516
442 6F7L FAD 5.64516
443 2Z9V PXM 5.64516
444 1H5Q NAP 5.66038
445 2AMT 1AA 5.66038
446 2WK1 SAH 5.67376
447 3U4C NDP 5.69395
448 3WDM ADN 5.74713
449 1Y8Q ATP 5.78035
450 1Q0S SAH 5.79151
451 1DJL NAP 5.7971
452 1FL2 FAD 5.80645
453 4ONQ SFG 5.88235
454 4BLW SAH 5.88235
455 4BLW AMP 5.88235
456 1YBH FAD 5.91398
457 3QWI CUE 5.92593
458 3QWI NAP 5.92593
459 3CTY FAD 5.95611
460 1ODJ GMP 5.95745
461 3G2O SAM 6.02007
462 5Z2L NDP 6.12245
463 1UWK URO 6.1828
464 1UWK NAD 6.1828
465 1JA9 NDP 6.20438
466 2PT9 2MH 6.23053
467 2PT9 S4M 6.23053
468 2GDZ NAD 6.36704
469 6DNT NAD 6.39535
470 5JJR SAH 6.45161
471 3RKR NAP 6.45161
472 5JWC FAD 6.45161
473 5HSA FAS 6.45161
474 1GEE NAD 6.51341
475 4GLL NAD 6.52819
476 4Y30 49L 6.55271
477 4Y30 SAH 6.55271
478 2GUD BMA 6.55738
479 2NU5 NAG 6.55738
480 2GUD MAN 6.55738
481 2GUC MAN 6.55738
482 2HYR BGC GLC 6.55738
483 2NUO BGC 6.55738
484 2HYQ MAN MAN 6.55738
485 3LU1 NAD 6.59341
486 1VE3 SAM 6.60793
487 3MB5 SAM 6.66667
488 4YMU ATP 6.66667
489 2DPM SAM 6.69014
490 1G0N PHH 6.71378
491 1G0N NDP 6.71378
492 1T9D P25 6.72043
493 5UAO FAD 6.72043
494 1T9D PYD 6.72043
495 1T9D 1MM 6.72043
496 5WKC FAD 6.72043
497 1T9D FAD 6.72043
498 4TM3 FAD 6.72043
499 2WOX NDP 6.72043
500 3EWP APR 6.77966
501 4NBU NAI 6.8
502 1O97 AMP 6.81818
503 1O97 FAD 6.81818
504 3RNM FAD 6.89655
505 6EQS BV8 6.90909
506 3RIY NAD 6.95971
507 2PXX SAH 6.97674
508 1V59 FAD 6.98925
509 1V59 NAD 6.98925
510 2VVL FAD 6.98925
511 2VVM FAD 6.98925
512 2ZWI C5P 6.98925
513 3VZS NAP 7.00389
514 3FUU ADN 7.01107
515 2I7C AAT 7.06714
516 5J60 FAD 7.1875
517 1JG3 ADN 7.23404
518 4UCI SAM 7.25806
519 5G3U ITW 7.25806
520 5G3U FDA 7.25806
521 1OAA OAA 7.33591
522 1H8P PC 7.33945
523 3HB5 NAP 7.33945
524 3WV8 ATP 7.33945
525 6F9Q NAD 7.35294
526 5D9X GSH 7.3913
527 3GU3 SAH 7.39437
528 5N0J FAD 7.40741
529 4ZCC NAI 7.44048
530 4ZCC FAD 7.44048
531 5XLX SAH 7.44681
532 3SJ7 NDP 7.53968
533 4ZBA GDS 7.62332
534 6ARJ BW4 7.73639
535 6ARJ SAH 7.73639
536 5DX8 SFG 7.73639
537 5DX1 SFG 7.73639
538 5DXA SFG 7.73639
539 5DWQ SFG 7.73639
540 5DX0 SFG 7.73639
541 3EGI ADP 7.76699
542 4CQM NAP 7.78689
543 1Q7B NAP 7.78689
544 3GCZ SAM 7.80142
545 1JNR FAD 8
546 2YY7 NAD 8.01282
547 5IL1 SAM 8.01887
548 1XCL SAH 8.08511
549 4R6W PC 8.13953
550 4R6W SAH 8.13953
551 3TN7 NJP 8.17121
552 3JWH SAH 8.29493
553 2CVQ NDP 8.56269
554 5FEU NAP 8.59107
555 3JQ7 NAP 8.60215
556 5JDC NAP 8.60215
557 5K6A NAP 8.60215
558 1XG5 NAP 8.60215
559 5DLY SAH 8.64662
560 5DLY 5D7 8.64662
561 1NNU NAD 8.73362
562 1NNU TCT 8.73362
563 6GFK SAH 8.76494
564 5B4T 3HR 8.84615
565 5B4T NAD 8.84615
566 4Y9D NAI 8.85246
567 4JDR FAD 8.87097
568 2GN4 NDP 9.01163
569 2GN4 UD1 9.01163
570 1ZQ9 SAM 9.12281
571 5X62 SAH 9.13978
572 5YRG BGC GLC 9.15493
573 4IWN GEK 9.17031
574 3AY6 NAI 9.29368
575 2AG5 NAD 9.34959
576 2ZWA SAH 9.4086
577 2Y6Q FAD 9.4086
578 3RJ5 NAD 9.44882
579 3HVJ 705 9.50226
580 1GTE FAD 9.67742
581 1R18 SAH 9.69163
582 5FFF 5XC 9.72763
583 5FFF NAP 9.72763
584 1MXH NAP 9.78261
585 1MXH DHF 9.78261
586 3ZV6 NAD 9.96441
587 3ZV6 4HB 9.96441
588 4NBT NAD 10
589 1LSS NAD 10
590 1P1C SAH 10.0503
591 4XFR CIT 10.0703
592 2DKN NAI 10.1961
593 5K7U SAM 10.2222
594 6DUB SAH 10.3604
595 5MGZ SAH 10.5932
596 5M58 SAH 10.8696
597 2F5Z FAD 10.9375
598 3C3Y SAH 10.9705
599 4CMI NAP 11.1111
600 3JQF NAP 11.1111
601 4CLR NAP 11.1111
602 3JQA NAP 11.1111
603 5JCJ NAP 11.1111
604 3BMN NAP 11.1111
605 4CM8 NAP 11.1111
606 3JQG NAP 11.1111
607 4CM4 NAP 11.1111
608 3JQB NAP 11.1111
609 4CM9 NAP 11.1111
610 4CME NAP 11.1111
611 3BMO NAP 11.1111
612 3JQ9 NAP 11.1111
613 5JDI NAP 11.1111
614 3BMQ NAP 11.1111
615 3JQ8 NAP 11.1111
616 2GAG NAD 11.1111
617 4NTO 1PW 11.1111
618 4NTD FAD 11.1765
619 5Y02 MXN 11.215
620 1DL5 SAH 11.3565
621 1XHL NDP 11.4478
622 1V35 NAI 11.5502
623 2XVM SAH 11.5578
624 5GT9 NAP 11.7871
625 2HMT NAI 11.8056
626 6FLZ MMA 11.8056
627 1BXK NAD 11.831
628 2VZ0 D64 11.9403
629 2VZ0 NAP 11.9403
630 2WD7 NAP 11.9403
631 3DXY SAM 12.0968
632 1ORR NAD 12.1037
633 3BGD SAH 12.3077
634 3BGD PM6 12.3077
635 4AZW SAM 12.6344
636 4YAC NAI 12.7946
637 5O42 BGC 13.1387
638 5O42 NAD 13.1387
639 5O42 9JW 13.1387
640 1ZK4 NAP 13.1474
641 1ZK4 AC0 13.1474
642 5YF1 8V0 13.2597
643 5YF1 SFG 13.2597
644 3FPF TNA 13.4228
645 3FPF MTA 13.4228
646 2JHP SAH 13.4409
647 2XYQ SAH 13.9344
648 4PIO AVI 14.2415
649 4PIO SAH 14.2415
650 4M73 SAH 14.2433
651 4M73 M72 14.2433
652 2NXE SAM 14.5669
653 2Q46 NAP 14.6245
654 1L1E SAH 14.6341
655 5VN0 NAI 15.0538
656 5VN0 FAD 15.0538
657 1TPY SAH 15.6794
658 2BGM NAJ 16.187
659 3FRH SAH 16.2055
660 1E6E FAD 16.4062
661 5THZ SAH 16.5432
662 3DMH SAM 16.7979
663 3DMH GMP 16.7979
664 1IM8 SAI 16.8033
665 4II2 ATP 17.1779
666 4DCM SAM 17.2043
667 1NFQ NAI 17.3077
668 4CNK FAD 17.4731
669 5L95 AMP 17.5
670 1RDL MMA 18.5841
671 1KPG SAH 21.6028
672 6D6Y SAH 21.7742
673 1EJ0 SAM 22.2222
674 1KPH SAH 22.2997
675 4QTU SAM 24.0385
676 5E1M SAH 27.8008
677 5E1M PRO PRO LYS ARG ILE ALA 27.8008
678 3GWZ SAH 36.0434
679 3GXO SAH 36.0434
680 1XDS SAM 36.3636
681 1QZZ SAM 36.631
682 5EEH P9P 40.0538
683 5EEH SAH 40.0538
684 4A6D SAM 40.7932
685 3I53 SAH 43.3735
686 5W7R SAH 43.5484
687 5W7R 9Z7 43.5484
Pocket No.: 4; Query (leader) PDB : 1FP1; Ligand: SAH; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 1fp1.bio1) has 19 residues
No: Leader PDB Ligand Sequence Similarity
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