Receptor
PDB id Resolution Class Description Source Keywords
1FZM 1.8 Å NON-ENZYME: IMMUNE MHC CLASS I NATURAL MUTANT H-2KBM8 HEAVY CHAIN COMPLEXED WIT MICROGLOBULIN AND VESICULAR STOMATITIS VIRUS NUCLEOPROTEIN MUS MUSCULUS MAJOR HISTOCOMPATIBILITY COMPLEX PEPTIDE-MHC IMMUNE SYSTEM
Ref.: THE CRYSTAL STRUCTURES OF K(BM1) AND K(BM8) REVEAL SUBTLE CHANGES IN THE PEPTIDE ENVIRONMENT IMPACT THERMOSTABILITY AND ALLOREACTIVITY. IMMUNITY V. 14 231 2001
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ARG GLY TYR VAL TYR GLN GLY LEU P:1;
Valid;
none;
Kd = 20 nM
956.092 n/a O=C([...
MPD A:702;
B:703;
Invalid;
Invalid;
none;
none;
submit data
118.174 C6 H14 O2 C[C@@...
MRD A:701;
Invalid;
none;
submit data
118.174 C6 H14 O2 C[C@H...
NAG A:500;
Part of Protein;
none;
submit data
221.208 C8 H15 N O6 CC(=O...
NAG NAG FUL C:1;
Part of Protein;
none;
submit data
n/a n/a
PO4 A:801;
B:802;
Part of Protein;
Part of Protein;
none;
none;
submit data
94.971 O4 P [O-]P...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1LEK 2.15 Å NON-ENZYME: IMMUNE CRYSTAL STRUCTURE OF H-2KBM3 BOUND TO DEV8 MUS MUSCULUS MHC CLASS I ALLOGENEIC COMPLEX WITH PEPTIDE IMMUNE SYSTEM
Ref.: STRUCTURAL COMPARISON OF ALLOGENEIC AND SYNGENEIC T RECEPTOR-PEPTIDE-MAJOR HISTOCOMPATIBILITY COMPLEX C A BURIED ALLOREACTIVE MUTATION SUBTLY ALTERS PEPTID PRESENTATION SUBSTANTIALLY INCREASING V(BETA) INTER J.EXP.MED. V. 195 1175
Members (36)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 222 families.
1 1WBZ - SER SER TYR ARG ARG PRO VAL GLY ILE n/a n/a
2 1VAD - SER ARG ASP HIS SER ARG THR PRO MET n/a n/a
3 1FZM Kd = 20 nM ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
4 4PV8 - ARG ABA PHE ILE PHE ALA ASN ILE n/a n/a
5 2ZSV - ARG ABA GLN ILE PHE ALA ASN ILE n/a n/a
6 2CLZ - ILE ASN PHE ASP PHE ASN THR ILE n/a n/a
7 1RK1 - SER GLU ILE GLU PHE ALA ARG LEU n/a n/a
8 3PAB Kd = 20 uM GLU ILE ILE ASN PHE GLU LYS LEU n/a n/a
9 1G7Q Kd = 877 nM SER ALA PRO ASP THR ARG PRO ALA n/a n/a
10 1FZO Kd = 13 nM PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
11 4HS3 - ALA VAL TYR ASN PHE ALA THR MET n/a n/a
12 4PV9 - ARG ABA VAL ILE PHE ALA ASN ILE n/a n/a
13 1LEK Kd = 1.3 nM GLU GLN TYR LYS PHE TYR SER VAL n/a n/a
14 4PG9 - PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
15 1NAN - ILE ASN PHE ASP PHE ASN THR ILE n/a n/a
16 2VAA - ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
17 2VAB - PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
18 2CLV - SER GLN TYR TYR TYR ASN SER LEU n/a n/a
19 1KJ3 - LYS VAL ILE THR PHE ILE ASP LEU n/a n/a
20 1RJY - SER SER ILE GLU PHE ALA ARG LEU n/a n/a
21 1FZJ Kd = 8 nM ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
22 1G7P Kd = 90 nM SER ARG ASP HIS SER ARG THR PRO MET n/a n/a
23 1KPU - ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
24 1T0N - SER SER ILE GLU PHE ALA ARG LEU n/a n/a
25 3P9L Kd = 6 uM SER ILE ILE ASN PHE GLU LYS LEU n/a n/a
26 1T0M - SER SER ILE GLU PHE ALA ARG LEU n/a n/a
27 1FZK Kd = 4 nM PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
28 1KPV - PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
29 1OSZ - ARG GLY TYR LEU TYR GLN GLY LEU n/a n/a
30 1LK2 ic50 = 12 uM GLY ASN TYR SER PHE TYR ALA LEU n/a n/a
31 1LEG Kd = 11.1 nM GLU GLN TYR LYS PHE TYR SER VAL n/a n/a
32 1KBG - ARG GLY TYR VAL TYR ESC GLY LEU GAL GLA n/a n/a
33 4PGE - PHE ALA PRO GLY ASN TYR PRO ALA TRP n/a n/a
34 6GB6 - GLY LEU n/a n/a
35 3P9M Kd = 10 uM SER ILE ILE GLY PHE GLU LYS LEU n/a n/a
36 1VAC - SER ILE ILE ASN PHE GLU LYS LEU n/a n/a
70% Homology Family (393)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 67 families.
1 4QRT - GLU LEU ASN ARG LYS MET ILE TYR MET n/a n/a
2 3KPN - GLU GLU TYR LEU GLN ALA PHE THR TYR n/a n/a
3 4U1H - THR PRO GLN ASP LEU ASN THR MET LEU n/a n/a
4 3LKP - LEU PRO PHE ASP LYS SER THR ILE MET n/a n/a
5 1A9E - LEU PRO PRO LEU ASP ILE THR PRO TYR n/a n/a
6 1W0W - ARG ARG LEU PRO ILE PHE SER ARG LEU n/a n/a
7 4G8I - LYS ARG TRP ILE ILE MET GLY LEU ASN LYS n/a n/a
8 5IND - GLN ALA SER GLN ASP VAL LYS ASN TRP n/a n/a
9 2BVP - ILE SER PRO ARG THR LEU ASP ALA TRP n/a n/a
10 6PYL - LYS ARG TRP ILE ILE LEU GLY LEU ASN LYS n/a n/a
11 5V5L - THR SER THR LEU GLN GLU GLN ILE GLY TRP n/a n/a
12 5DEG - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
13 1UXS - ARG ARG ARG TRP ARG ARG LEU THR VAL n/a n/a
14 3VRJ - LEU THR THR LYS LEU THR ASN THR ASN ILE n/a n/a
15 3BP4 - ILE ARG ALA ALA PRO PRO PRO LEU PHE n/a n/a
16 3X12 - LEU SER SER PRO VAL THR LYS SER PHE n/a n/a
17 6PYJ - LEU ARG ASN GLN SER VAL PHE ASN PHE n/a n/a
18 6MTL - PHE GLU ASP LEU ARG VAL LEU SER PHE n/a n/a
19 4O2C ic50 = 10 nM ACE SER HIS VAL ALA VAL GLU ASN ALA LEU n/a n/a
20 5WMP - THR PRO ARG VAL THR GLY GLY GLY ALA MET n/a n/a
21 5DEF - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
22 4U1M - ARG PRO GLN VAL PRO LEU ARG PRO MET n/a n/a
23 5IM7 - GLN ALA SER GLN GLU VAL LYS ASN TRP n/a n/a
24 1A1N - VAL PRO LEU ARG PRO MET THR TYR n/a n/a
25 1OGT - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
26 3KPO - GLU GLU TYR LEU LYS ALA TRP THR PHE n/a n/a
27 5WMR - GLN ILE LYS VAL ARG VAL ASP MET VAL n/a n/a
28 2A83 - ARG ARG ARG TRP HIS ARG TRP ARG LEU n/a n/a
29 6PYW - LEU ARG ASN GLN SER VAL PHE ASN PHE n/a n/a
30 3B6S - ARG ARG LYS TRP CIR ARG TRP HIS LEU n/a n/a
31 1JGD - ARG ARG LEU LEU ARG GLY HIS ASN GLN TYR n/a n/a
32 5EO0 - ARG PRO MET THR PHE LYS GLY ALA LEU n/a n/a
33 1HSA - ALA ARG ALA ALA ALA ALA ALA ALA ALA n/a n/a
34 1AGE - GLY GLY LYS LYS LYS TYR ARG LEU n/a n/a
35 4JQV - SER GLU LEU GLU ILE LYS ARG TYR n/a n/a
36 3X11 - LEU SER SER PRO VAL THR LYS SER PHE n/a n/a
37 1M6O - GLU GLU PHE GLY ARG ALA PHE SER PHE n/a n/a
38 6MT3 - PHE GLU ASP LEU ARG VAL LEU SER PHE n/a n/a
39 4G9D - LYS ARG TRP ILE ILE LEU GLY LEU ASN LYS n/a n/a
40 6BXP - ARG VAL LYS GLU LYS TYR GLN HIS LEU KYN n/a n/a
41 3LKR - LEU PRO PHE GLU ARG ALA THR VAL MET n/a n/a
42 3KPP - GLU GLU TYR LEU GLN ALA PHE THR TYR n/a n/a
43 1K5N - GLY ARG PHE ALA ALA ALA ILE ALA LYS n/a n/a
44 6MT4 - PHE GLU ASP LEU ARG VAL SER SER PHE n/a n/a
45 4O2E - SER HIS VAL ALA VAL GLU ASN ALA LEU n/a n/a
46 4U1N - ARG PRO GLN VAL PRO LEU ARG PRO MET n/a n/a
47 3BP7 - ILE ARG ALA ALA PRO PRO PRO LEU PHE n/a n/a
48 1XR9 - ILE LEU GLY PRO PRO GLY SER VAL TYR n/a n/a
49 5WMN - SER PRO ILE VAL PRO SER PHE ASP MET n/a n/a
50 1AGD - GLY GLY LYS LYS LYS TYR LYS LEU n/a n/a
51 3LKO - LEU PRO PHE ASP ARG THR THR ILE MET n/a n/a
52 1SYS - GLU GLU PRO THR VAL ILE LYS LYS TYR n/a n/a
53 3KPM - GLU GLU TYR LEU LYS ALA TRP THR PHE n/a n/a
54 4U1S - PHE PRO ARG PRO TRP LEU HIS GLY LEU n/a n/a
55 4U1K - ARG PRO GLN VAL PRO LEU ARG PRO MET n/a n/a
56 5U98 Kd = 0.2 nM VAL THR THR ASP ILE GLN VAL LYS VAL n/a n/a
57 2H6P - LYS PRO ILE VAL VAL LEU HIS GLY TYR n/a n/a
58 4XXC - ASP GLU LEU GLU ILE LYS ALA TYR n/a n/a
59 3UPR - HIS SER ILE THR TYR LEU LEU PRO VAL n/a n/a
60 4QRQ Kd = 2.48 uM HIS SER LYS LYS LYS CYS ASP GLU LEU n/a n/a
61 3X13 - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
62 3VRI - ARG VAL ALA GLN LEU GLU GLN VAL TYR ILE n/a n/a
63 3LV3 - SER ARG ARG TRP ARG ARG TRP ASN ARG n/a n/a
64 1UXW - ARG ARG ARG TRP ARG ARG LEU THR VAL n/a n/a
65 1XR8 - LEU GLU LYS ALA ARG GLY SER THR TYR n/a n/a
66 1AGC - GLY GLY LYS LYS LYS TYR GLN LEU n/a n/a
67 5WMO - ARG PRO PRO ILE PHE ILE ARG ARG LEU n/a n/a
68 1A1M - THR PRO TYR ASP ILE ASN GLN MET LEU n/a n/a
69 4U1L - ARG PRO GLN VAL PRO LEU ARG PRO MET n/a n/a
70 3SKO - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
71 3BXN - ILE ARG ALA ALA PRO PRO PRO LEU PHE n/a n/a
72 1A1O - LYS PRO ILE VAL GLN TYR ASP ASN PHE n/a n/a
73 3DX7 - GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE n/a n/a
74 6PZ5 - LEU ARG ASN GLN SER VAL PHE ASN PHE n/a n/a
75 5W67 - VAL ARG SER ARG ARG ABA LEU ARG LEU n/a n/a
76 5EO1 - ARG PRO MET THR TYR LYS GLY ALA LEU n/a n/a
77 1M05 - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
78 5TXS - ALA GLN ASP ILE TYR ARG ALA SER TYR n/a n/a
79 6PYV - LEU ARG ASN GLN SER VAL PHE ASN PHE n/a n/a
80 2BSR - ARG ARG ILE TYR ASP LEU ILE GLU LEU n/a n/a
81 5WMQ - GLU LEU ARG SER ARG TYR TRP ALA ILE n/a n/a
82 4QRS - GLU LEU LYS ARG LYS MET ILE TYR MET n/a n/a
83 2BST - SER ARG TYR TRP ALA ILE ARG THR ARG n/a n/a
84 4U1I - THR PRO GLN ASP LEU ASN THR MET LEU n/a n/a
85 6BXQ - ARG VAL LYS GLU LYS TYR GLN HIS LEU TRP n/a n/a
86 6MT5 - PHE GLU ASP LEU ARG LEU LEU SER PHE n/a n/a
87 1AGB - GLY GLY ARG LYS LYS TYR LYS LEU n/a n/a
88 3LKQ - LEU PRO PHE ASP LYS THR THR ILE MET n/a n/a
89 2AXG - ALA PRO GLN PRO ALA PRO GLU ASN ALA TYR n/a n/a
90 3DX6 - GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE n/a n/a
91 1AGF - GLY GLY LYS LYS ARG TYR LYS LEU n/a n/a
92 2CIK - LYS PRO ILE VAL VAL LEU HIS GLY TYR n/a n/a
93 3LKN - LEU PRO PHE GLU ARG ALA THR ILE MET n/a n/a
94 2BSS - LYS ARG TRP ILE ILE LEU GLY LEU ASN LYS n/a n/a
95 3C9N - VAL GLN GLN GLU SER SER PHE VAL MET n/a n/a
96 4U1J - THR PRO GLN ASP LEU ASN THR MET LEU n/a n/a
97 3B3I - ARG ARG LYS TRP CIR ARG TRP HIS LEU n/a n/a
98 3DX8 - GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE n/a n/a
99 3KPL - GLU GLU TYR LEU GLN ALA PHE THR TYR n/a n/a
100 5VGD - SER ALA GLU PRO VAL PRO LEU GLN LEU n/a n/a
101 1OF2 - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
102 1W0V - ARG ARG LEU PRO ILE PHE SER ARG LEU n/a n/a
103 1E27 - LEU PRO PRO VAL VAL ALA LYS GLU ILE n/a n/a
104 6MT6 - PHE GLU ASP LEU ARG VAL LEU SER PHE n/a n/a
105 1JGE - GLY ARG PHE ALA ALA ALA ILE ALA LYS n/a n/a
106 5T6W - SER SER THR ARG GLY ILE SER GLN LEU TRP n/a n/a
107 3X14 - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
108 1N2R - GLU GLU PHE GLY ARG ALA PHE SER PHE n/a n/a
109 4QRU - GLU LEU ARG ARG LYS MET MET TYR MET n/a n/a
110 5W6A - ALA ARG THR GLU LEU TYR ARG SER LEU n/a n/a
111 2AXF - ALA PRO GLN PRO ALA PRO GLU ASN ALA TYR n/a n/a
112 4NT6 - GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
113 3BWA - PHE PRO THR LYS ASP VAL ALA LEU n/a n/a
114 5T6X - THR SER THR THR SER VAL ALA SER SER TRP n/a n/a
115 4O2F - HIS VAL ALA VAL GLU ASN ALA LEU n/a n/a
116 3SKM - PHE LEU ARG GLY ARG ALA TYR VAL LEU n/a n/a
117 1SYV - GLU GLU PHE GLY ARG ALA PHE SER PHE n/a n/a
118 3KPQ - GLU GLU TYR LEU LYS ALA TRP THR PHE n/a n/a
119 3LKS - LEU PRO PHE GLU LYS SER THR VAL MET n/a n/a
120 1B0G - ALA LEU TRP GLY PHE PHE PRO VAL LEU n/a n/a
121 3GSW - ASN LEU VAL PRO MET VAL ALA ALA VAL n/a n/a
122 5HGA - ARG PHE PRO LEU THR PHE GLY TRP n/a n/a
123 2X4O - LYS LEU THR PRO LEU CYS VAL THR LEU n/a n/a
124 5N6B - LEU LEU TRP ASN GLY PRO MET ALA VAL n/a n/a
125 6PTE - ILE LEU ASN ALA MET ILE THR LYS ILE n/a n/a
126 1QR1 - ILE ILE SER ALA VAL VAL GLY ILE LEU n/a n/a
127 3O3B - GLU LEU ALA GIC 3AZ LEU THR VAL n/a n/a
128 5C0I - ARG GLN PHE GLY PRO ASP PHE PRO THR ILE n/a n/a
129 5N1Y - MET VAL TRP GLY PRO ASP PRO LEU TYR VAL n/a n/a
130 5GSD - SER SER CYS PRO LEU SER LYS n/a n/a
131 1I1Y - TYR LEU LYS GLU PRO VAL HIS GLY VAL n/a n/a
132 3FT3 ic50 = 44 nM VAL LEU HIS ASP ASP LEU LEU GLU ALA n/a n/a
133 2VLL - GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
134 1T1Z - ALA LEU TYR ASN THR ALA ALA ALA LEU n/a n/a
135 3FQT - GLY LEU LEU GLY SER PRO VAL ARG ALA n/a n/a
136 3GSQ - ASN LEU VAL PRO SER VAL ALA THR VAL n/a n/a
137 4NQX - CYS THR GLU LEU LYS LEU ASN ASP TYR n/a n/a
138 6J1V - ALA ILE PHE GLN SER SER MET THR LYS n/a n/a
139 3VXN - ARG TYR PRO LEU THR PHE GLY TRP CYS PHE n/a n/a
140 5C0J - ARG GLN PHE GLY PRO ASP TRP ILE VAL ALA n/a n/a
141 1DUZ - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
142 3H7B Kd = 41 uM MET LEU TRP GLY TYR LEU GLN TYR VAL n/a n/a
143 3WL9 - ASN TYR THR PRO GLY PRO GLY ILE ARG PHE n/a n/a
144 4JFP - GLU LEU ALA ALA ILE GLY ILE LEU THR VAL n/a n/a
145 3FQW - ARG VAL ALA SER PRO THR SER GLY VAL n/a n/a
146 1TVB - ILE THR ASP GLN VAL PRO PHE SER VAL n/a n/a
147 1T1W - SER LEU PHE ASN THR ILE ALA VAL LEU n/a n/a
148 5C0F - ARG GLN TRP GLY PRO ASP PRO ALA ALA VAL n/a n/a
149 3MYJ - TYR MET PHE PRO ASN ALA PRO TYR LEU n/a n/a
150 4WJ5 ic50 = 0.51 uM GRN NVA ALA GLY ILE GLY ILE LEU THR LPH n/a n/a
151 1Q94 - ALA ILE PHE GLN SER SER MET THR LYS n/a n/a
152 3H9H Kd = 5.4 uM MET LEU TRP GLY TYR LEU GLN TYR VAL n/a n/a
153 3O3E - BAL LEU ALA TIG 3AZ LEU THR VAL n/a n/a
154 4I4W - ILE LEU ALA LYS PHE LEU HIS ARG LEU n/a n/a
155 2X4R - ASN LEU VAL PRO MET VAL ALA THR VAL n/a n/a
156 4HWZ - ALA ILE PHE GLN SER SER MET THR LYS n/a n/a
157 3PWJ Kd = 70 uM LEU LEU TYR GLY PHE VAL ASN TYR VAL n/a n/a
158 3FQN - TYR LEU ASP SER GLY ILE HIS SER GLY ALA n/a n/a
159 3BHB ic50 = 3.4 nM LYS MET ASP SEP PHE LEU ASP MET GLN LEU n/a n/a
160 1S9W - SER LEU LEU MET TRP ILE THR GLN CYS n/a n/a
161 5C0G - TYR LEU GLY GLY PRO ASP PHE PRO THR ILE n/a n/a
162 4HX1 - SER VAL TYR ASP PHE PHE VAL TRP LEU n/a n/a
163 3MGO - ARG LEU TYR GLN ASN PRO THR THR TYR ILE n/a n/a
164 1I7R - PHE ALA PRO GLY PHE PHE PRO TYR LEU n/a n/a
165 1X7Q - LYS THR PHE PRO PRO THR GLU PRO LYS n/a n/a
166 3WLB - ASN TYR THR PRO GLY PRO GLY THR ARG PHE n/a n/a
167 3RL2 - GLN VAL PRO LEU ARG PRO MET THR TYR LYS n/a n/a
168 2GUO - ALA ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
169 4JFQ - GLU LEU ALA GLY ILE GLY ILE ALA THR VAL n/a n/a
170 5EU4 - TYR LEU ALA PRO GLY PRO VAL THR ALA n/a n/a
171 1I7U - ALA LEU TRP GLY PHE VAL PRO VAL LEU n/a n/a
172 5C0D - ALA GLN TRP GLY PRO ASP PRO ALA ALA ALA n/a n/a
173 3GSO Kd = 27.7 uM ASN LEU VAL PRO MET VAL ALA THR VAL n/a n/a
174 3HPJ - ARG MET PHE PRO ASN ALA PRO TYR LEU n/a n/a
175 3KLA Kd = 31.1 uM SER LEU LEU MET TRP ILE THR GLN LEU n/a n/a
176 4K7F - VAL CYS TRP GLY GLU LEU MET ASN LEU n/a n/a
177 2V2W Kd = 2.2 uM SER LEU TYR ASN THR VAL ALA THR LEU n/a n/a
178 5SWQ - CYS VAL ASN GLY SER CYS PHE THR VAL n/a n/a
179 3I6L - GLN PHE LYS ASP ASN VAL ILE LEU LEU n/a n/a
180 1QVO - GLN VAL PRO LEU ARG PRO MET THR TYR LYS n/a n/a
181 2GIT - LEU LEU PHE GLY LYS PRO VAL TYR VAL n/a n/a
182 5EU5 - TYR LEU GLU PRO ALA PRO VAL THR ALA n/a n/a
183 2X70 - LYS ILE LEU GLY PRV VAL PHE PRQ VAL n/a n/a
184 2GTZ - ALA LEU GLY ILE GLY ILE LEU THR VAL n/a n/a
185 3OXR - PHE LEU PRO SER ASP PHE PHE PRO SER VAL n/a n/a
186 1T1Y - SER LEU TYR ASN VAL VAL ALA THR LEU n/a n/a
187 1EEZ - ILE LEU SER ALA LEU VAL GLY ILE LEU n/a n/a
188 1TVH - ILE MET ASP GLN VAL PRO PHE SER VAL n/a n/a
189 6PTB - ILE LEU ASN ALA MET ILE ALA LYS ILE n/a n/a
190 3REW Kd = 28.8 uM CYS LEU GLY GLY LEU LEU THR MET VAL n/a n/a
191 5MEQ Kd = 28 uM ILE LEU ALA LYS PHE LEU HIS THR LEU n/a n/a
192 3I6G - GLY LEU MET TRP LEU SER TYR PHE VAL n/a n/a
193 5NMH - SER LEU TYR ASN THR ILE ALA THR LEU n/a n/a
194 2C7U Kd = 100 nM SER LEU PHE ASN THR ILE ALA VAL LEU n/a n/a
195 1EEY - ILE LEU SER ALA LEU VAL GLY ILE VAL n/a n/a
196 1HHJ - ILE LEU LYS GLU PRO VAL HIS GLY VAL n/a n/a
197 5HGB - ARG TYR PRO LEU THR PHE GLY TRP n/a n/a
198 6G3J - MET THR SER ALA ILE GLY ILE LEU PRO VAL n/a n/a
199 2GTW - LEU ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
200 3GSV Kd = 57.5 uM ASN LEU VAL PRO GLN VAL ALA THR VAL n/a n/a
201 3D25 ic50 = 22 nM VAL LEU HIS ASP ASP LEU LEU GLU ALA n/a n/a
202 5EU3 - TYR LEU GLU PRO GLY PRO VAL THR ALA n/a n/a
203 3BH9 ic50 = 116.9 nM ARG THR TYR SEP GLY PRO MET ASN LYS VAL n/a n/a
204 3OXS - PHE LEU PRO SER ASP PHE PHE PRO SER VAL n/a n/a
205 2V2X Kd = 5.2 uM SER LEU PHE ASN THR VAL ALA THR LEU n/a n/a
206 4JFO Kd = 140 uM ALA LEU ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
207 5HHP - GLY ILE LEU GLU PHE VAL PHE THR LEU n/a n/a
208 4GKS - PHE LEU THR GLY ILE GLY ILE ILE THR VAL n/a n/a
209 1T20 - SER LEU TYR ASN THR ILE ALA THR LEU n/a n/a
210 3GIV - SER LEU PHE ASN THR VAL ALA THR LEU TYR n/a n/a
211 3VXP - ARG TYR PRO LEU THR LEU GLY TRP CYS PHE n/a n/a
212 3PWL Kd = 140 uM LEU GLY TYR GLY PHE VAL ASN TYR ILE n/a n/a
213 5NMK - SER LEU PHE ASN THR ILE ALA VAL LEU n/a n/a
214 6J2A - CYS THR GLU LEU LYS LEU SER ASP TYR n/a n/a
215 6J29 - GLN ILE MET TYR ASN TYR PRO ALA MET n/a n/a
216 5C0E - TYR GLN PHE GLY PRO ASP PHE PRO ILE ALA n/a n/a
217 3UTQ - ALA LEU TRP GLY PRO ASP PRO ALA ALA ALA n/a n/a
218 4F7P - PHE TYR ARG TYR GLY PHE VAL ALA ASN PHE n/a n/a
219 3RL1 - ALA ILE PHE GLN SER SER MET THR LYS n/a n/a
220 5HGH - ARG TYR PRO LEU THR PHE GLY TRP CYS PHE n/a n/a
221 3QFD Kd = 68 uM ALA ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
222 3O3A - BAL LEU ALA GIC 3AZ LEU THR VAL n/a n/a
223 2X4N - LYS ILE LEU GLY PRV VAL PHE PRQ VAL n/a n/a
224 4F7T - ARG TYR GLY PHE VAL ALA ASN PHE n/a n/a
225 5GRD - SER SER CYS SER SER CYS PRO LEU SER LYS n/a n/a
226 5MEO Kd = 1 uM ILE LEU GLY LYS PHE LEU HIS ARG LEU n/a n/a
227 3GSU Kd = 58.2 uM ASN LEU VAL PRO THR VAL ALA THR VAL n/a n/a
228 5HGD - ARG PHE PRO LEU THR PHE GLY TRP CYS PHE n/a n/a
229 3IXA Kd = 9.8 uM LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
230 3FT2 ic50 = 44 nM VAL LEU CIR ASP ASP LEU LEU GLU ALA n/a n/a
231 2GT9 - GLU ALA ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
232 5MER - ILE LEU ALA LYS PHE LEU HIS GLU LEU n/a n/a
233 5HHN - GLY ILE LEU GLY LEU VAL PHE THR LEU n/a n/a
234 2CLR - MET LEU LEU SER VAL PRO LEU LEU LEU GLY n/a n/a
235 1T22 - SER LEU TYR ASN THR VAL ALA THR LEU n/a n/a
236 1I4F - GLY VAL TYR ASP GLY ARG GLU HIS THR VAL n/a n/a
237 3NFN - ARG TYR PRO LEU THR PHE GLY TRP CYS PHE n/a n/a
238 3FQU - GLY LEU LEU GLY SEP PRO VAL ARG ALA n/a n/a
239 1JF1 - GLU LEU ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
240 1HHK - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
241 3BH8 ic50 = 11.2 nM ARG GLN ALA SEP ILE GLU LEU PRO SER MET n/a n/a
242 3BGM ic50 = 32.5 nM ARG GLN ALA SEP LEU SER ILE SER VAL n/a n/a
243 3O3D - GLU LEU ALA TIG 3AZ LEU THR VAL n/a n/a
244 3PWN Kd = 48 uM LEU LEU TYR GLY PHE VAL ASN TYR ILE n/a n/a
245 3MGT - LYS LEU TYR GLN ASN PRO THR THR TYR ILE n/a n/a
246 6OPD - ILE LEU ASN ALA MET ILE VAL LYS ILE n/a n/a
247 3FQX - ARG VAL ALA SEP PRO THR SER GLY VAL n/a n/a
248 1S9Y - SER LEU LEU MET TRP ILE THR GLN SER n/a n/a
249 2AV7 - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
250 1S8D - SER LEU ALA ASN THR VAL ALA THR LEU n/a n/a
251 4F7M - LEU TYR ALA SER PRO GLN LEU GLU GLY PHE n/a n/a
252 6J1W - ALA ILE PHE GLN SER SER MET THR LYS n/a n/a
253 3OX8 - PHE LEU PRO SER ASP PHE PHE PRO SER VAL n/a n/a
254 3GSX - ASN LEU VAL PRO MET VAL ALA VAL VAL n/a n/a
255 1T1X - SER LEU TYR LEU THR VAL ALA THR LEU n/a n/a
256 1DUY - LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
257 1S9X - SER LEU LEU MET TRP ILE THR GLN ALA n/a n/a
258 2X4P - MSE ILE LEU GLY PRV VAL PHE PRQ VAL n/a n/a
259 3FT4 ic50 = 1171 nM VAL LEU ARG ASP ASP LEU LEU GLU ALA n/a n/a
260 1HHI - GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
261 1JHT - ALA LEU GLY ILE GLY ILE LEU THR VAL n/a n/a
262 2X4U - ILE LEU LYS GLU PRO VAL HIS GLY VAL n/a n/a
263 4NQV - CYS THR GLU LEU LYS LEU SER ASP TYR n/a n/a
264 5HHQ - GLY ILE TRP GLY PHE VAL PHE THR LEU n/a n/a
265 1T21 - SER LEU TYR ASN THR VAL ALA THR LEU n/a n/a
266 3BO8 - GLU ALA ASP PRO THR GLY HIS SER TYR n/a n/a
267 2AV1 - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
268 3GSR Kd = 60.2 uM ASN LEU VAL PRO VAL VAL ALA THR VAL n/a n/a
269 1QEW - PHE LEU TRP GLY PRO ARG ALA LEU VAL n/a n/a
270 1HSB - ALA VAL ALA n/a n/a
271 2HN7 ic50 = 31 nM ALA ILE MET PRO ALA ARG PHE TYR PRO LYS n/a n/a
272 3FQR - TYR LEU ASP SEP GLY ILE HIS SER GLY ALA n/a n/a
273 5GRG - SER SER CYS SER SER CYS n/a n/a
274 2RFX - LEU SER SER PRO VAL THR LYS SER PHE n/a n/a
275 5VCL - ALA MET ALA PRO ARG THR LEU LEU LEU n/a n/a
276 3VJ6 Kd = 17 uM ALA MET ALA PRO ARG THR LEU LEU LEU n/a n/a
277 1WBZ - SER SER TYR ARG ARG PRO VAL GLY ILE n/a n/a
278 1VAD - SER ARG ASP HIS SER ARG THR PRO MET n/a n/a
279 1FZM Kd = 20 nM ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
280 4PV8 - ARG ABA PHE ILE PHE ALA ASN ILE n/a n/a
281 2ZSV - ARG ABA GLN ILE PHE ALA ASN ILE n/a n/a
282 2CLZ - ILE ASN PHE ASP PHE ASN THR ILE n/a n/a
283 1RK1 - SER GLU ILE GLU PHE ALA ARG LEU n/a n/a
284 3PAB Kd = 20 uM GLU ILE ILE ASN PHE GLU LYS LEU n/a n/a
285 1G7Q Kd = 877 nM SER ALA PRO ASP THR ARG PRO ALA n/a n/a
286 1FZO Kd = 13 nM PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
287 4HS3 - ALA VAL TYR ASN PHE ALA THR MET n/a n/a
288 4PV9 - ARG ABA VAL ILE PHE ALA ASN ILE n/a n/a
289 1LEK Kd = 1.3 nM GLU GLN TYR LYS PHE TYR SER VAL n/a n/a
290 4PG9 - PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
291 1NAN - ILE ASN PHE ASP PHE ASN THR ILE n/a n/a
292 2VAA - ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
293 2VAB - PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
294 2CLV - SER GLN TYR TYR TYR ASN SER LEU n/a n/a
295 1KJ3 - LYS VAL ILE THR PHE ILE ASP LEU n/a n/a
296 1RJY - SER SER ILE GLU PHE ALA ARG LEU n/a n/a
297 1FZJ Kd = 8 nM ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
298 1G7P Kd = 90 nM SER ARG ASP HIS SER ARG THR PRO MET n/a n/a
299 1KPU - ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
300 1T0N - SER SER ILE GLU PHE ALA ARG LEU n/a n/a
301 3P9L Kd = 6 uM SER ILE ILE ASN PHE GLU LYS LEU n/a n/a
302 1T0M - SER SER ILE GLU PHE ALA ARG LEU n/a n/a
303 1FZK Kd = 4 nM PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
304 1KPV - PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
305 1OSZ - ARG GLY TYR LEU TYR GLN GLY LEU n/a n/a
306 1LK2 ic50 = 12 uM GLY ASN TYR SER PHE TYR ALA LEU n/a n/a
307 1LEG Kd = 11.1 nM GLU GLN TYR LYS PHE TYR SER VAL n/a n/a
308 1KBG - ARG GLY TYR VAL TYR ESC GLY LEU GAL GLA n/a n/a
309 4PGE - PHE ALA PRO GLY ASN TYR PRO ALA TRP n/a n/a
310 6GB6 - GLY LEU n/a n/a
311 3P9M Kd = 10 uM SER ILE ILE GLY PHE GLU LYS LEU n/a n/a
312 1VAC - SER ILE ILE ASN PHE GLU LYS LEU n/a n/a
313 6IWG - MYR GLY GLY ALA ILE n/a n/a
314 6IWH - MYR GLY GLY GLY ILE n/a n/a
315 3PWU - ILE PRO ALA TYR GLY VAL LEU THR ILE n/a n/a
316 3CC5 - LYS VAL PRO ARG ASN GLN ASP TRP LEU n/a n/a
317 5MZM - MET CYS PRO ARG MET THR ALA VAL MET n/a n/a
318 4L8B - ALA SER ASN GLU HIS MET GLU THR MET n/a n/a
319 3CPL - ALA SER ASN GLU ASN ALA GLU THR MET n/a n/a
320 1WBY - SER SER LEU GLU ASN PHE ARG ALA TYR VAL n/a n/a
321 3CH1 - GLU GLY PRO ARG ASN GLN ASP TRP LEU n/a n/a
322 4HV8 - ALA SER ASN GLU ASN ILE GLU THR MET n/a n/a
323 1WBX - SER GLN LEU LYS ASN ASN ALA LYS GLU ILE n/a n/a
324 1YN7 - SER SER LEU GLU ASN PHE ALA ALA TYR VAL n/a n/a
325 1YN6 - SER SER LEU GLU ASN PHE ARG ALA TYR VAL n/a n/a
326 1JUF ic50 = 1400 nM SER SER VAL ILE GLY VAL TRP TYR LEU n/a n/a
327 1JPG - PHE GLN PRO GLN ASN GLY GLN PHE ILE n/a n/a
328 5E8O - MET ABA LEU ARG MET THR ALA VAL MET n/a n/a
329 1LD9 - TYR PRO ASN VAL ASN ILE HIS ASN PHE n/a n/a
330 5E8P - MET CYS LEU ARG NLE THR ALA VAL MET n/a n/a
331 1HOC - ALA SER ASN GLU ASN MET GLU THR MET n/a n/a
332 4HUX - ALA SER ASN GLU ASN MET GLU THR MET n/a n/a
333 4HUV - ALA SER ASN GLU ASN TRP GLU THR MET n/a n/a
334 1INQ ic50 = 539 nM SER SER VAL VAL GLY VAL TRP TYR LEU n/a n/a
335 2ZOK - ABA SER LEU TRP ASN GLY PRO HIS LEU n/a n/a
336 5E8N - MET CYS LEU ARG MET THR ALA VAL MET n/a n/a
337 4HUU - ALA SER ASN GLU ASN ILE GLU THR MET n/a n/a
338 4L8D - ALA SER ASN GLU ASP MET GLU THR MET n/a n/a
339 1S7Q - LYS ALA VAL TYR ASN PHE ALA THR MET n/a n/a
340 1S7T - LYS ALA VAL PHE ASN PHE ALA THR MET n/a n/a
341 6J2E - ASP PHE GLN GLU SER ALA ASP SER PHE LEU n/a n/a
342 6J2J - ASP PHE THR CYS SER GLN ILE SER PRO n/a n/a
343 6J2H - ASP PHE ALA ASN THR PHE LEU PRO n/a n/a
344 6K7T - ASP PHE ALA ASN THR PHE LEU PRO n/a n/a
345 6J2I - ASP PHE GLU LYS GLU GLY TYR SER LEU n/a n/a
346 4ZFZ Kd = 2.5 uM GLY GLY ALA ILE SER MYR n/a n/a
347 3RWG ic50 = 2.8 nM MET HIS PRO ALA GLN THR SER GLN TRP n/a n/a
348 3RWI ic50 = 116 nM GLY SER HIS LEU GLU VAL GLN GLY TYR TRP n/a n/a
349 3RWC ic50 = 7.6 nM ILE ARG TYR PRO LYS THR PHE GLY TRP n/a n/a
350 3RWE ic50 = 43 nM PHE GLN TRP MET GLY TYR GLU LEU TRP n/a n/a
351 3FOM - ILE GLN GLN SER ILE GLU ARG ILE n/a n/a
352 3FON - VAL ASN ASP ILE PHE GLU ALA ILE n/a n/a
353 5GSV - PHE TYR ALA PRO GLU PRO ILE THR SER LEU n/a n/a
354 4WDI Kd = 286 uM LEU TYR LEU VAL CYS GLY GLU ARG GLY n/a n/a
355 5GSR - TYR TYR SER ILE ALA PRO HIS SER ILE n/a n/a
356 5GR7 - TYR TYR SER ILE ILE PRO HIS SER ILE n/a n/a
357 4Z78 Kd = 113 uM LEU TYR LEU VAL CYS GLY GLU ARG GLY PHE n/a n/a
358 4Z76 Kd = 13.6 uM LEU TYR LEU VAL CYS GLY GLU ARG VAL n/a n/a
359 5GSX - PHE TYR ALA PRO GLU PRO ILE THR SER LEU n/a n/a
360 5GSB - LYS TYR TYR SER ILE ILE PRO HIS SER ILE n/a n/a
361 3BZF - VAL MET ALA PRO ARG ALA LEU LEU LEU n/a n/a
362 6GH4 - ARG GLN PRO ALA LYS ALA PRO LEU LEU n/a n/a
363 6GH1 - ARG LEU PRO ALA LYS ALA PRO LEU LEU n/a n/a
364 3BZE - VAL MET ALA PRO ARG THR LEU PHE LEU n/a n/a
365 5H94 - LYS MET ASN THR GLN PHE THR ALA VAL n/a n/a
366 3QQ4 - ALA THR ALA ALA ALA THR GLU ALA TYR n/a n/a
367 5XS3 - VAL ARG SER ARG ARG CYS LEU ARG LEU n/a n/a
368 3ECB - ARG GLY PRO GLY ARG ALA PHE VAL THR ILE n/a n/a
369 5WEU Kd = 0.19 mM ARG GLY PRO GLY CYS ALA PHE VAL THR ILE n/a n/a
370 3E6F - ILE GLY PRO GLY ARG ALA PHE TYR ALA n/a n/a
371 5KD7 - ILE GLY PRO GLY ARG ALA PHE TYR VAL n/a n/a
372 3E6H - ILE GLY PRO GLY ARG ALA PHE TYR THR ILE n/a n/a
373 5T7G - ILE GLY PRO GLY ARG ALA PHE TYR THR n/a n/a
374 1MHC - FME TYR PHE ILE ASN ILE LEU THR LEU n/a n/a
375 6O9B - THR THR ALA PRO SER LEU SER GLY LYS n/a n/a
376 6O9C - THR THR ALA PRO PHE LEU SER GLY LYS n/a n/a
377 1ZT1 - PHE GLU ALA ASN GLY ASN LEU ILE n/a n/a
378 1K8D - ILE LEU MET GLU HIS ILE HIS LYS LEU n/a n/a
379 1KJM - ALA GLN PHE SER ALA SER ALA SER ARG n/a n/a
380 5J6H - NCA C6 H6 N2 O c1cc(cnc1)....
381 1KJV - ASN PRO ARG ALA MET GLN ALA LEU LEU n/a n/a
382 1YDP - ARG ILE ILE PRO ARG HIS LEU GLN LEU n/a n/a
383 3KYN - LYS GLY PRO PRO ALA ALA LEU THR LEU n/a n/a
384 3KYO - LYS LEU PRO ALA GLN PHE TYR ILE LEU n/a n/a
385 6J2F - ASP TYR ILE ASN THR ASN VAL LEU PRO n/a n/a
386 6J2D - ASP PHE ALA ASN THR PHE LEU PRO n/a n/a
387 6ILC - ASP PHE ALA ASN THR PHE LEU PRO n/a n/a
388 1S7X - LYS ALA VAL PHE ASN PHE ALA THR MET n/a n/a
389 6GB5 - PHE ALA PRO GLY ASN TYR PRO n/a n/a
390 6GB7 - GLU ASP ALA GLY GLY GLY GLY LEU SER LYS n/a n/a
391 1S7U - LYS ALA VAL TYR ASN PHE ALA THR MET n/a n/a
392 1S7V - LYS ALA VAL TYR ASN LEU ALA THR MET n/a n/a
393 1S7W - LYS ALA LEU TYR ASN PHE ALA THR MET n/a n/a
50% Homology Family (399)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 45 families.
1 4QRT - GLU LEU ASN ARG LYS MET ILE TYR MET n/a n/a
2 3KPN - GLU GLU TYR LEU GLN ALA PHE THR TYR n/a n/a
3 4U1H - THR PRO GLN ASP LEU ASN THR MET LEU n/a n/a
4 3LKP - LEU PRO PHE ASP LYS SER THR ILE MET n/a n/a
5 1A9E - LEU PRO PRO LEU ASP ILE THR PRO TYR n/a n/a
6 1W0W - ARG ARG LEU PRO ILE PHE SER ARG LEU n/a n/a
7 4G8I - LYS ARG TRP ILE ILE MET GLY LEU ASN LYS n/a n/a
8 5IND - GLN ALA SER GLN ASP VAL LYS ASN TRP n/a n/a
9 2BVP - ILE SER PRO ARG THR LEU ASP ALA TRP n/a n/a
10 6PYL - LYS ARG TRP ILE ILE LEU GLY LEU ASN LYS n/a n/a
11 5V5L - THR SER THR LEU GLN GLU GLN ILE GLY TRP n/a n/a
12 5DEG - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
13 1UXS - ARG ARG ARG TRP ARG ARG LEU THR VAL n/a n/a
14 3VRJ - LEU THR THR LYS LEU THR ASN THR ASN ILE n/a n/a
15 3BP4 - ILE ARG ALA ALA PRO PRO PRO LEU PHE n/a n/a
16 3X12 - LEU SER SER PRO VAL THR LYS SER PHE n/a n/a
17 6PYJ - LEU ARG ASN GLN SER VAL PHE ASN PHE n/a n/a
18 6MTL - PHE GLU ASP LEU ARG VAL LEU SER PHE n/a n/a
19 4O2C ic50 = 10 nM ACE SER HIS VAL ALA VAL GLU ASN ALA LEU n/a n/a
20 5WMP - THR PRO ARG VAL THR GLY GLY GLY ALA MET n/a n/a
21 5DEF - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
22 4U1M - ARG PRO GLN VAL PRO LEU ARG PRO MET n/a n/a
23 5IM7 - GLN ALA SER GLN GLU VAL LYS ASN TRP n/a n/a
24 1A1N - VAL PRO LEU ARG PRO MET THR TYR n/a n/a
25 1OGT - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
26 3KPO - GLU GLU TYR LEU LYS ALA TRP THR PHE n/a n/a
27 5WMR - GLN ILE LYS VAL ARG VAL ASP MET VAL n/a n/a
28 2A83 - ARG ARG ARG TRP HIS ARG TRP ARG LEU n/a n/a
29 6PYW - LEU ARG ASN GLN SER VAL PHE ASN PHE n/a n/a
30 3B6S - ARG ARG LYS TRP CIR ARG TRP HIS LEU n/a n/a
31 1JGD - ARG ARG LEU LEU ARG GLY HIS ASN GLN TYR n/a n/a
32 5EO0 - ARG PRO MET THR PHE LYS GLY ALA LEU n/a n/a
33 1HSA - ALA ARG ALA ALA ALA ALA ALA ALA ALA n/a n/a
34 1AGE - GLY GLY LYS LYS LYS TYR ARG LEU n/a n/a
35 4JQV - SER GLU LEU GLU ILE LYS ARG TYR n/a n/a
36 3X11 - LEU SER SER PRO VAL THR LYS SER PHE n/a n/a
37 1M6O - GLU GLU PHE GLY ARG ALA PHE SER PHE n/a n/a
38 6MT3 - PHE GLU ASP LEU ARG VAL LEU SER PHE n/a n/a
39 4G9D - LYS ARG TRP ILE ILE LEU GLY LEU ASN LYS n/a n/a
40 6BXP - ARG VAL LYS GLU LYS TYR GLN HIS LEU KYN n/a n/a
41 3LKR - LEU PRO PHE GLU ARG ALA THR VAL MET n/a n/a
42 3KPP - GLU GLU TYR LEU GLN ALA PHE THR TYR n/a n/a
43 1K5N - GLY ARG PHE ALA ALA ALA ILE ALA LYS n/a n/a
44 6MT4 - PHE GLU ASP LEU ARG VAL SER SER PHE n/a n/a
45 4O2E - SER HIS VAL ALA VAL GLU ASN ALA LEU n/a n/a
46 4U1N - ARG PRO GLN VAL PRO LEU ARG PRO MET n/a n/a
47 3BP7 - ILE ARG ALA ALA PRO PRO PRO LEU PHE n/a n/a
48 1XR9 - ILE LEU GLY PRO PRO GLY SER VAL TYR n/a n/a
49 5WMN - SER PRO ILE VAL PRO SER PHE ASP MET n/a n/a
50 1AGD - GLY GLY LYS LYS LYS TYR LYS LEU n/a n/a
51 3LKO - LEU PRO PHE ASP ARG THR THR ILE MET n/a n/a
52 1SYS - GLU GLU PRO THR VAL ILE LYS LYS TYR n/a n/a
53 3KPM - GLU GLU TYR LEU LYS ALA TRP THR PHE n/a n/a
54 4U1S - PHE PRO ARG PRO TRP LEU HIS GLY LEU n/a n/a
55 4U1K - ARG PRO GLN VAL PRO LEU ARG PRO MET n/a n/a
56 5U98 Kd = 0.2 nM VAL THR THR ASP ILE GLN VAL LYS VAL n/a n/a
57 2H6P - LYS PRO ILE VAL VAL LEU HIS GLY TYR n/a n/a
58 4XXC - ASP GLU LEU GLU ILE LYS ALA TYR n/a n/a
59 3UPR - HIS SER ILE THR TYR LEU LEU PRO VAL n/a n/a
60 4QRQ Kd = 2.48 uM HIS SER LYS LYS LYS CYS ASP GLU LEU n/a n/a
61 3X13 - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
62 3VRI - ARG VAL ALA GLN LEU GLU GLN VAL TYR ILE n/a n/a
63 3LV3 - SER ARG ARG TRP ARG ARG TRP ASN ARG n/a n/a
64 1UXW - ARG ARG ARG TRP ARG ARG LEU THR VAL n/a n/a
65 1XR8 - LEU GLU LYS ALA ARG GLY SER THR TYR n/a n/a
66 1AGC - GLY GLY LYS LYS LYS TYR GLN LEU n/a n/a
67 5WMO - ARG PRO PRO ILE PHE ILE ARG ARG LEU n/a n/a
68 1A1M - THR PRO TYR ASP ILE ASN GLN MET LEU n/a n/a
69 4U1L - ARG PRO GLN VAL PRO LEU ARG PRO MET n/a n/a
70 3SKO - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
71 3BXN - ILE ARG ALA ALA PRO PRO PRO LEU PHE n/a n/a
72 1A1O - LYS PRO ILE VAL GLN TYR ASP ASN PHE n/a n/a
73 3DX7 - GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE n/a n/a
74 6PZ5 - LEU ARG ASN GLN SER VAL PHE ASN PHE n/a n/a
75 5W67 - VAL ARG SER ARG ARG ABA LEU ARG LEU n/a n/a
76 5EO1 - ARG PRO MET THR TYR LYS GLY ALA LEU n/a n/a
77 1M05 - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
78 5TXS - ALA GLN ASP ILE TYR ARG ALA SER TYR n/a n/a
79 6PYV - LEU ARG ASN GLN SER VAL PHE ASN PHE n/a n/a
80 2BSR - ARG ARG ILE TYR ASP LEU ILE GLU LEU n/a n/a
81 5WMQ - GLU LEU ARG SER ARG TYR TRP ALA ILE n/a n/a
82 4QRS - GLU LEU LYS ARG LYS MET ILE TYR MET n/a n/a
83 2BST - SER ARG TYR TRP ALA ILE ARG THR ARG n/a n/a
84 4U1I - THR PRO GLN ASP LEU ASN THR MET LEU n/a n/a
85 6BXQ - ARG VAL LYS GLU LYS TYR GLN HIS LEU TRP n/a n/a
86 6MT5 - PHE GLU ASP LEU ARG LEU LEU SER PHE n/a n/a
87 1AGB - GLY GLY ARG LYS LYS TYR LYS LEU n/a n/a
88 3LKQ - LEU PRO PHE ASP LYS THR THR ILE MET n/a n/a
89 2AXG - ALA PRO GLN PRO ALA PRO GLU ASN ALA TYR n/a n/a
90 3DX6 - GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE n/a n/a
91 1AGF - GLY GLY LYS LYS ARG TYR LYS LEU n/a n/a
92 2CIK - LYS PRO ILE VAL VAL LEU HIS GLY TYR n/a n/a
93 3LKN - LEU PRO PHE GLU ARG ALA THR ILE MET n/a n/a
94 2BSS - LYS ARG TRP ILE ILE LEU GLY LEU ASN LYS n/a n/a
95 3C9N - VAL GLN GLN GLU SER SER PHE VAL MET n/a n/a
96 4U1J - THR PRO GLN ASP LEU ASN THR MET LEU n/a n/a
97 3B3I - ARG ARG LYS TRP CIR ARG TRP HIS LEU n/a n/a
98 3DX8 - GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE n/a n/a
99 3KPL - GLU GLU TYR LEU GLN ALA PHE THR TYR n/a n/a
100 5VGD - SER ALA GLU PRO VAL PRO LEU GLN LEU n/a n/a
101 1OF2 - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
102 1W0V - ARG ARG LEU PRO ILE PHE SER ARG LEU n/a n/a
103 1E27 - LEU PRO PRO VAL VAL ALA LYS GLU ILE n/a n/a
104 6MT6 - PHE GLU ASP LEU ARG VAL LEU SER PHE n/a n/a
105 1JGE - GLY ARG PHE ALA ALA ALA ILE ALA LYS n/a n/a
106 5T6W - SER SER THR ARG GLY ILE SER GLN LEU TRP n/a n/a
107 3X14 - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
108 1N2R - GLU GLU PHE GLY ARG ALA PHE SER PHE n/a n/a
109 4QRU - GLU LEU ARG ARG LYS MET MET TYR MET n/a n/a
110 5W6A - ALA ARG THR GLU LEU TYR ARG SER LEU n/a n/a
111 2AXF - ALA PRO GLN PRO ALA PRO GLU ASN ALA TYR n/a n/a
112 4NT6 - GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
113 3BWA - PHE PRO THR LYS ASP VAL ALA LEU n/a n/a
114 5T6X - THR SER THR THR SER VAL ALA SER SER TRP n/a n/a
115 4O2F - HIS VAL ALA VAL GLU ASN ALA LEU n/a n/a
116 3SKM - PHE LEU ARG GLY ARG ALA TYR VAL LEU n/a n/a
117 1SYV - GLU GLU PHE GLY ARG ALA PHE SER PHE n/a n/a
118 3KPQ - GLU GLU TYR LEU LYS ALA TRP THR PHE n/a n/a
119 3LKS - LEU PRO PHE GLU LYS SER THR VAL MET n/a n/a
120 1B0G - ALA LEU TRP GLY PHE PHE PRO VAL LEU n/a n/a
121 3GSW - ASN LEU VAL PRO MET VAL ALA ALA VAL n/a n/a
122 5HGA - ARG PHE PRO LEU THR PHE GLY TRP n/a n/a
123 2X4O - LYS LEU THR PRO LEU CYS VAL THR LEU n/a n/a
124 5N6B - LEU LEU TRP ASN GLY PRO MET ALA VAL n/a n/a
125 6PTE - ILE LEU ASN ALA MET ILE THR LYS ILE n/a n/a
126 1QR1 - ILE ILE SER ALA VAL VAL GLY ILE LEU n/a n/a
127 3O3B - GLU LEU ALA GIC 3AZ LEU THR VAL n/a n/a
128 5C0I - ARG GLN PHE GLY PRO ASP PHE PRO THR ILE n/a n/a
129 5N1Y - MET VAL TRP GLY PRO ASP PRO LEU TYR VAL n/a n/a
130 5GSD - SER SER CYS PRO LEU SER LYS n/a n/a
131 1I1Y - TYR LEU LYS GLU PRO VAL HIS GLY VAL n/a n/a
132 3FT3 ic50 = 44 nM VAL LEU HIS ASP ASP LEU LEU GLU ALA n/a n/a
133 2VLL - GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
134 1T1Z - ALA LEU TYR ASN THR ALA ALA ALA LEU n/a n/a
135 3FQT - GLY LEU LEU GLY SER PRO VAL ARG ALA n/a n/a
136 3GSQ - ASN LEU VAL PRO SER VAL ALA THR VAL n/a n/a
137 4NQX - CYS THR GLU LEU LYS LEU ASN ASP TYR n/a n/a
138 6J1V - ALA ILE PHE GLN SER SER MET THR LYS n/a n/a
139 3VXN - ARG TYR PRO LEU THR PHE GLY TRP CYS PHE n/a n/a
140 5C0J - ARG GLN PHE GLY PRO ASP TRP ILE VAL ALA n/a n/a
141 1DUZ - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
142 3H7B Kd = 41 uM MET LEU TRP GLY TYR LEU GLN TYR VAL n/a n/a
143 3WL9 - ASN TYR THR PRO GLY PRO GLY ILE ARG PHE n/a n/a
144 4JFP - GLU LEU ALA ALA ILE GLY ILE LEU THR VAL n/a n/a
145 3FQW - ARG VAL ALA SER PRO THR SER GLY VAL n/a n/a
146 1TVB - ILE THR ASP GLN VAL PRO PHE SER VAL n/a n/a
147 1T1W - SER LEU PHE ASN THR ILE ALA VAL LEU n/a n/a
148 5C0F - ARG GLN TRP GLY PRO ASP PRO ALA ALA VAL n/a n/a
149 3MYJ - TYR MET PHE PRO ASN ALA PRO TYR LEU n/a n/a
150 4WJ5 ic50 = 0.51 uM GRN NVA ALA GLY ILE GLY ILE LEU THR LPH n/a n/a
151 1Q94 - ALA ILE PHE GLN SER SER MET THR LYS n/a n/a
152 3H9H Kd = 5.4 uM MET LEU TRP GLY TYR LEU GLN TYR VAL n/a n/a
153 3O3E - BAL LEU ALA TIG 3AZ LEU THR VAL n/a n/a
154 4I4W - ILE LEU ALA LYS PHE LEU HIS ARG LEU n/a n/a
155 2X4R - ASN LEU VAL PRO MET VAL ALA THR VAL n/a n/a
156 4HWZ - ALA ILE PHE GLN SER SER MET THR LYS n/a n/a
157 3PWJ Kd = 70 uM LEU LEU TYR GLY PHE VAL ASN TYR VAL n/a n/a
158 3FQN - TYR LEU ASP SER GLY ILE HIS SER GLY ALA n/a n/a
159 3BHB ic50 = 3.4 nM LYS MET ASP SEP PHE LEU ASP MET GLN LEU n/a n/a
160 1S9W - SER LEU LEU MET TRP ILE THR GLN CYS n/a n/a
161 5C0G - TYR LEU GLY GLY PRO ASP PHE PRO THR ILE n/a n/a
162 4HX1 - SER VAL TYR ASP PHE PHE VAL TRP LEU n/a n/a
163 3MGO - ARG LEU TYR GLN ASN PRO THR THR TYR ILE n/a n/a
164 1I7R - PHE ALA PRO GLY PHE PHE PRO TYR LEU n/a n/a
165 1X7Q - LYS THR PHE PRO PRO THR GLU PRO LYS n/a n/a
166 3WLB - ASN TYR THR PRO GLY PRO GLY THR ARG PHE n/a n/a
167 3RL2 - GLN VAL PRO LEU ARG PRO MET THR TYR LYS n/a n/a
168 2GUO - ALA ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
169 4JFQ - GLU LEU ALA GLY ILE GLY ILE ALA THR VAL n/a n/a
170 5EU4 - TYR LEU ALA PRO GLY PRO VAL THR ALA n/a n/a
171 1I7U - ALA LEU TRP GLY PHE VAL PRO VAL LEU n/a n/a
172 5C0D - ALA GLN TRP GLY PRO ASP PRO ALA ALA ALA n/a n/a
173 3GSO Kd = 27.7 uM ASN LEU VAL PRO MET VAL ALA THR VAL n/a n/a
174 3HPJ - ARG MET PHE PRO ASN ALA PRO TYR LEU n/a n/a
175 3KLA Kd = 31.1 uM SER LEU LEU MET TRP ILE THR GLN LEU n/a n/a
176 4K7F - VAL CYS TRP GLY GLU LEU MET ASN LEU n/a n/a
177 2V2W Kd = 2.2 uM SER LEU TYR ASN THR VAL ALA THR LEU n/a n/a
178 5SWQ - CYS VAL ASN GLY SER CYS PHE THR VAL n/a n/a
179 3I6L - GLN PHE LYS ASP ASN VAL ILE LEU LEU n/a n/a
180 1QVO - GLN VAL PRO LEU ARG PRO MET THR TYR LYS n/a n/a
181 2GIT - LEU LEU PHE GLY LYS PRO VAL TYR VAL n/a n/a
182 5EU5 - TYR LEU GLU PRO ALA PRO VAL THR ALA n/a n/a
183 2X70 - LYS ILE LEU GLY PRV VAL PHE PRQ VAL n/a n/a
184 2GTZ - ALA LEU GLY ILE GLY ILE LEU THR VAL n/a n/a
185 3OXR - PHE LEU PRO SER ASP PHE PHE PRO SER VAL n/a n/a
186 1T1Y - SER LEU TYR ASN VAL VAL ALA THR LEU n/a n/a
187 1EEZ - ILE LEU SER ALA LEU VAL GLY ILE LEU n/a n/a
188 1TVH - ILE MET ASP GLN VAL PRO PHE SER VAL n/a n/a
189 6PTB - ILE LEU ASN ALA MET ILE ALA LYS ILE n/a n/a
190 3REW Kd = 28.8 uM CYS LEU GLY GLY LEU LEU THR MET VAL n/a n/a
191 5MEQ Kd = 28 uM ILE LEU ALA LYS PHE LEU HIS THR LEU n/a n/a
192 3I6G - GLY LEU MET TRP LEU SER TYR PHE VAL n/a n/a
193 5NMH - SER LEU TYR ASN THR ILE ALA THR LEU n/a n/a
194 2C7U Kd = 100 nM SER LEU PHE ASN THR ILE ALA VAL LEU n/a n/a
195 1EEY - ILE LEU SER ALA LEU VAL GLY ILE VAL n/a n/a
196 1HHJ - ILE LEU LYS GLU PRO VAL HIS GLY VAL n/a n/a
197 5HGB - ARG TYR PRO LEU THR PHE GLY TRP n/a n/a
198 6G3J - MET THR SER ALA ILE GLY ILE LEU PRO VAL n/a n/a
199 2GTW - LEU ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
200 3GSV Kd = 57.5 uM ASN LEU VAL PRO GLN VAL ALA THR VAL n/a n/a
201 3D25 ic50 = 22 nM VAL LEU HIS ASP ASP LEU LEU GLU ALA n/a n/a
202 5EU3 - TYR LEU GLU PRO GLY PRO VAL THR ALA n/a n/a
203 3BH9 ic50 = 116.9 nM ARG THR TYR SEP GLY PRO MET ASN LYS VAL n/a n/a
204 3OXS - PHE LEU PRO SER ASP PHE PHE PRO SER VAL n/a n/a
205 2V2X Kd = 5.2 uM SER LEU PHE ASN THR VAL ALA THR LEU n/a n/a
206 4JFO Kd = 140 uM ALA LEU ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
207 5HHP - GLY ILE LEU GLU PHE VAL PHE THR LEU n/a n/a
208 4GKS - PHE LEU THR GLY ILE GLY ILE ILE THR VAL n/a n/a
209 1T20 - SER LEU TYR ASN THR ILE ALA THR LEU n/a n/a
210 3GIV - SER LEU PHE ASN THR VAL ALA THR LEU TYR n/a n/a
211 3VXP - ARG TYR PRO LEU THR LEU GLY TRP CYS PHE n/a n/a
212 3PWL Kd = 140 uM LEU GLY TYR GLY PHE VAL ASN TYR ILE n/a n/a
213 5NMK - SER LEU PHE ASN THR ILE ALA VAL LEU n/a n/a
214 6J2A - CYS THR GLU LEU LYS LEU SER ASP TYR n/a n/a
215 6J29 - GLN ILE MET TYR ASN TYR PRO ALA MET n/a n/a
216 5C0E - TYR GLN PHE GLY PRO ASP PHE PRO ILE ALA n/a n/a
217 3UTQ - ALA LEU TRP GLY PRO ASP PRO ALA ALA ALA n/a n/a
218 4F7P - PHE TYR ARG TYR GLY PHE VAL ALA ASN PHE n/a n/a
219 3RL1 - ALA ILE PHE GLN SER SER MET THR LYS n/a n/a
220 5HGH - ARG TYR PRO LEU THR PHE GLY TRP CYS PHE n/a n/a
221 3QFD Kd = 68 uM ALA ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
222 3O3A - BAL LEU ALA GIC 3AZ LEU THR VAL n/a n/a
223 2X4N - LYS ILE LEU GLY PRV VAL PHE PRQ VAL n/a n/a
224 4F7T - ARG TYR GLY PHE VAL ALA ASN PHE n/a n/a
225 5GRD - SER SER CYS SER SER CYS PRO LEU SER LYS n/a n/a
226 5MEO Kd = 1 uM ILE LEU GLY LYS PHE LEU HIS ARG LEU n/a n/a
227 3GSU Kd = 58.2 uM ASN LEU VAL PRO THR VAL ALA THR VAL n/a n/a
228 5HGD - ARG PHE PRO LEU THR PHE GLY TRP CYS PHE n/a n/a
229 3IXA Kd = 9.8 uM LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
230 3FT2 ic50 = 44 nM VAL LEU CIR ASP ASP LEU LEU GLU ALA n/a n/a
231 2GT9 - GLU ALA ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
232 5MER - ILE LEU ALA LYS PHE LEU HIS GLU LEU n/a n/a
233 5HHN - GLY ILE LEU GLY LEU VAL PHE THR LEU n/a n/a
234 2CLR - MET LEU LEU SER VAL PRO LEU LEU LEU GLY n/a n/a
235 1T22 - SER LEU TYR ASN THR VAL ALA THR LEU n/a n/a
236 1I4F - GLY VAL TYR ASP GLY ARG GLU HIS THR VAL n/a n/a
237 3NFN - ARG TYR PRO LEU THR PHE GLY TRP CYS PHE n/a n/a
238 3FQU - GLY LEU LEU GLY SEP PRO VAL ARG ALA n/a n/a
239 1JF1 - GLU LEU ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
240 1HHK - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
241 3BH8 ic50 = 11.2 nM ARG GLN ALA SEP ILE GLU LEU PRO SER MET n/a n/a
242 3BGM ic50 = 32.5 nM ARG GLN ALA SEP LEU SER ILE SER VAL n/a n/a
243 3O3D - GLU LEU ALA TIG 3AZ LEU THR VAL n/a n/a
244 3PWN Kd = 48 uM LEU LEU TYR GLY PHE VAL ASN TYR ILE n/a n/a
245 3MGT - LYS LEU TYR GLN ASN PRO THR THR TYR ILE n/a n/a
246 6OPD - ILE LEU ASN ALA MET ILE VAL LYS ILE n/a n/a
247 3FQX - ARG VAL ALA SEP PRO THR SER GLY VAL n/a n/a
248 1S9Y - SER LEU LEU MET TRP ILE THR GLN SER n/a n/a
249 2AV7 - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
250 1S8D - SER LEU ALA ASN THR VAL ALA THR LEU n/a n/a
251 4F7M - LEU TYR ALA SER PRO GLN LEU GLU GLY PHE n/a n/a
252 6J1W - ALA ILE PHE GLN SER SER MET THR LYS n/a n/a
253 3OX8 - PHE LEU PRO SER ASP PHE PHE PRO SER VAL n/a n/a
254 3GSX - ASN LEU VAL PRO MET VAL ALA VAL VAL n/a n/a
255 1T1X - SER LEU TYR LEU THR VAL ALA THR LEU n/a n/a
256 1DUY - LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
257 1S9X - SER LEU LEU MET TRP ILE THR GLN ALA n/a n/a
258 2X4P - MSE ILE LEU GLY PRV VAL PHE PRQ VAL n/a n/a
259 3FT4 ic50 = 1171 nM VAL LEU ARG ASP ASP LEU LEU GLU ALA n/a n/a
260 1HHI - GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
261 1JHT - ALA LEU GLY ILE GLY ILE LEU THR VAL n/a n/a
262 2X4U - ILE LEU LYS GLU PRO VAL HIS GLY VAL n/a n/a
263 4NQV - CYS THR GLU LEU LYS LEU SER ASP TYR n/a n/a
264 5HHQ - GLY ILE TRP GLY PHE VAL PHE THR LEU n/a n/a
265 1T21 - SER LEU TYR ASN THR VAL ALA THR LEU n/a n/a
266 3BO8 - GLU ALA ASP PRO THR GLY HIS SER TYR n/a n/a
267 2AV1 - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
268 3GSR Kd = 60.2 uM ASN LEU VAL PRO VAL VAL ALA THR VAL n/a n/a
269 1QEW - PHE LEU TRP GLY PRO ARG ALA LEU VAL n/a n/a
270 1HSB - ALA VAL ALA n/a n/a
271 2HN7 ic50 = 31 nM ALA ILE MET PRO ALA ARG PHE TYR PRO LYS n/a n/a
272 3FQR - TYR LEU ASP SEP GLY ILE HIS SER GLY ALA n/a n/a
273 5GRG - SER SER CYS SER SER CYS n/a n/a
274 2RFX - LEU SER SER PRO VAL THR LYS SER PHE n/a n/a
275 5VCL - ALA MET ALA PRO ARG THR LEU LEU LEU n/a n/a
276 3VJ6 Kd = 17 uM ALA MET ALA PRO ARG THR LEU LEU LEU n/a n/a
277 1WBZ - SER SER TYR ARG ARG PRO VAL GLY ILE n/a n/a
278 1VAD - SER ARG ASP HIS SER ARG THR PRO MET n/a n/a
279 1FZM Kd = 20 nM ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
280 4PV8 - ARG ABA PHE ILE PHE ALA ASN ILE n/a n/a
281 2ZSV - ARG ABA GLN ILE PHE ALA ASN ILE n/a n/a
282 2CLZ - ILE ASN PHE ASP PHE ASN THR ILE n/a n/a
283 1RK1 - SER GLU ILE GLU PHE ALA ARG LEU n/a n/a
284 3PAB Kd = 20 uM GLU ILE ILE ASN PHE GLU LYS LEU n/a n/a
285 1G7Q Kd = 877 nM SER ALA PRO ASP THR ARG PRO ALA n/a n/a
286 1FZO Kd = 13 nM PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
287 4HS3 - ALA VAL TYR ASN PHE ALA THR MET n/a n/a
288 4PV9 - ARG ABA VAL ILE PHE ALA ASN ILE n/a n/a
289 1LEK Kd = 1.3 nM GLU GLN TYR LYS PHE TYR SER VAL n/a n/a
290 4PG9 - PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
291 1NAN - ILE ASN PHE ASP PHE ASN THR ILE n/a n/a
292 2VAA - ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
293 2VAB - PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
294 2CLV - SER GLN TYR TYR TYR ASN SER LEU n/a n/a
295 1KJ3 - LYS VAL ILE THR PHE ILE ASP LEU n/a n/a
296 1RJY - SER SER ILE GLU PHE ALA ARG LEU n/a n/a
297 1FZJ Kd = 8 nM ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
298 1G7P Kd = 90 nM SER ARG ASP HIS SER ARG THR PRO MET n/a n/a
299 1KPU - ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
300 1T0N - SER SER ILE GLU PHE ALA ARG LEU n/a n/a
301 3P9L Kd = 6 uM SER ILE ILE ASN PHE GLU LYS LEU n/a n/a
302 1T0M - SER SER ILE GLU PHE ALA ARG LEU n/a n/a
303 1FZK Kd = 4 nM PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
304 1KPV - PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
305 1OSZ - ARG GLY TYR LEU TYR GLN GLY LEU n/a n/a
306 1LK2 ic50 = 12 uM GLY ASN TYR SER PHE TYR ALA LEU n/a n/a
307 1LEG Kd = 11.1 nM GLU GLN TYR LYS PHE TYR SER VAL n/a n/a
308 1KBG - ARG GLY TYR VAL TYR ESC GLY LEU GAL GLA n/a n/a
309 4PGE - PHE ALA PRO GLY ASN TYR PRO ALA TRP n/a n/a
310 6GB6 - GLY LEU n/a n/a
311 3P9M Kd = 10 uM SER ILE ILE GLY PHE GLU LYS LEU n/a n/a
312 1VAC - SER ILE ILE ASN PHE GLU LYS LEU n/a n/a
313 6IWG - MYR GLY GLY ALA ILE n/a n/a
314 6IWH - MYR GLY GLY GLY ILE n/a n/a
315 3PWU - ILE PRO ALA TYR GLY VAL LEU THR ILE n/a n/a
316 3CC5 - LYS VAL PRO ARG ASN GLN ASP TRP LEU n/a n/a
317 5MZM - MET CYS PRO ARG MET THR ALA VAL MET n/a n/a
318 4L8B - ALA SER ASN GLU HIS MET GLU THR MET n/a n/a
319 3CPL - ALA SER ASN GLU ASN ALA GLU THR MET n/a n/a
320 1WBY - SER SER LEU GLU ASN PHE ARG ALA TYR VAL n/a n/a
321 3CH1 - GLU GLY PRO ARG ASN GLN ASP TRP LEU n/a n/a
322 4HV8 - ALA SER ASN GLU ASN ILE GLU THR MET n/a n/a
323 1WBX - SER GLN LEU LYS ASN ASN ALA LYS GLU ILE n/a n/a
324 1YN7 - SER SER LEU GLU ASN PHE ALA ALA TYR VAL n/a n/a
325 1YN6 - SER SER LEU GLU ASN PHE ARG ALA TYR VAL n/a n/a
326 1JUF ic50 = 1400 nM SER SER VAL ILE GLY VAL TRP TYR LEU n/a n/a
327 1JPG - PHE GLN PRO GLN ASN GLY GLN PHE ILE n/a n/a
328 5E8O - MET ABA LEU ARG MET THR ALA VAL MET n/a n/a
329 1LD9 - TYR PRO ASN VAL ASN ILE HIS ASN PHE n/a n/a
330 5E8P - MET CYS LEU ARG NLE THR ALA VAL MET n/a n/a
331 1HOC - ALA SER ASN GLU ASN MET GLU THR MET n/a n/a
332 4HUX - ALA SER ASN GLU ASN MET GLU THR MET n/a n/a
333 4HUV - ALA SER ASN GLU ASN TRP GLU THR MET n/a n/a
334 1INQ ic50 = 539 nM SER SER VAL VAL GLY VAL TRP TYR LEU n/a n/a
335 2ZOK - ABA SER LEU TRP ASN GLY PRO HIS LEU n/a n/a
336 5E8N - MET CYS LEU ARG MET THR ALA VAL MET n/a n/a
337 4HUU - ALA SER ASN GLU ASN ILE GLU THR MET n/a n/a
338 4L8D - ALA SER ASN GLU ASP MET GLU THR MET n/a n/a
339 1S7Q - LYS ALA VAL TYR ASN PHE ALA THR MET n/a n/a
340 1S7T - LYS ALA VAL PHE ASN PHE ALA THR MET n/a n/a
341 6J2E - ASP PHE GLN GLU SER ALA ASP SER PHE LEU n/a n/a
342 6J2J - ASP PHE THR CYS SER GLN ILE SER PRO n/a n/a
343 6J2H - ASP PHE ALA ASN THR PHE LEU PRO n/a n/a
344 6K7T - ASP PHE ALA ASN THR PHE LEU PRO n/a n/a
345 6J2I - ASP PHE GLU LYS GLU GLY TYR SER LEU n/a n/a
346 4G43 - ILE ASP TRP PHE GLU GLY LYS GLU n/a n/a
347 4E0R - ILE ASP TRP PHE ASP GLY LYS GLU n/a n/a
348 4G42 - ILE ASP TRP PHE ASP GLY LYS ASP n/a n/a
349 4ZFZ Kd = 2.5 uM GLY GLY ALA ILE SER MYR n/a n/a
350 4CVZ - TYR GLU LEU ASP GLU LYS PHE ASP ARG LEU n/a n/a
351 3RWG ic50 = 2.8 nM MET HIS PRO ALA GLN THR SER GLN TRP n/a n/a
352 3RWI ic50 = 116 nM GLY SER HIS LEU GLU VAL GLN GLY TYR TRP n/a n/a
353 3RWC ic50 = 7.6 nM ILE ARG TYR PRO LYS THR PHE GLY TRP n/a n/a
354 3RWE ic50 = 43 nM PHE GLN TRP MET GLY TYR GLU LEU TRP n/a n/a
355 1BII - ARG GLY PRO GLY ARG ALA PHE VAL THR ILE n/a n/a
356 3FOM - ILE GLN GLN SER ILE GLU ARG ILE n/a n/a
357 3FON - VAL ASN ASP ILE PHE GLU ALA ILE n/a n/a
358 5GSV - PHE TYR ALA PRO GLU PRO ILE THR SER LEU n/a n/a
359 4WDI Kd = 286 uM LEU TYR LEU VAL CYS GLY GLU ARG GLY n/a n/a
360 5GSR - TYR TYR SER ILE ALA PRO HIS SER ILE n/a n/a
361 5GR7 - TYR TYR SER ILE ILE PRO HIS SER ILE n/a n/a
362 4Z78 Kd = 113 uM LEU TYR LEU VAL CYS GLY GLU ARG GLY PHE n/a n/a
363 4Z76 Kd = 13.6 uM LEU TYR LEU VAL CYS GLY GLU ARG VAL n/a n/a
364 5GSX - PHE TYR ALA PRO GLU PRO ILE THR SER LEU n/a n/a
365 5GSB - LYS TYR TYR SER ILE ILE PRO HIS SER ILE n/a n/a
366 3BZF - VAL MET ALA PRO ARG ALA LEU LEU LEU n/a n/a
367 6GH4 - ARG GLN PRO ALA LYS ALA PRO LEU LEU n/a n/a
368 6GH1 - ARG LEU PRO ALA LYS ALA PRO LEU LEU n/a n/a
369 3BZE - VAL MET ALA PRO ARG THR LEU PHE LEU n/a n/a
370 5H94 - LYS MET ASN THR GLN PHE THR ALA VAL n/a n/a
371 3QQ4 - ALA THR ALA ALA ALA THR GLU ALA TYR n/a n/a
372 5XS3 - VAL ARG SER ARG ARG CYS LEU ARG LEU n/a n/a
373 3ECB - ARG GLY PRO GLY ARG ALA PHE VAL THR ILE n/a n/a
374 5WEU Kd = 0.19 mM ARG GLY PRO GLY CYS ALA PHE VAL THR ILE n/a n/a
375 3E6F - ILE GLY PRO GLY ARG ALA PHE TYR ALA n/a n/a
376 5KD7 - ILE GLY PRO GLY ARG ALA PHE TYR VAL n/a n/a
377 3E6H - ILE GLY PRO GLY ARG ALA PHE TYR THR ILE n/a n/a
378 5T7G - ILE GLY PRO GLY ARG ALA PHE TYR THR n/a n/a
379 1MHC - FME TYR PHE ILE ASN ILE LEU THR LEU n/a n/a
380 6O9B - THR THR ALA PRO SER LEU SER GLY LYS n/a n/a
381 6O9C - THR THR ALA PRO PHE LEU SER GLY LYS n/a n/a
382 1ZT1 - PHE GLU ALA ASN GLY ASN LEU ILE n/a n/a
383 1K8D - ILE LEU MET GLU HIS ILE HIS LYS LEU n/a n/a
384 1KJM - ALA GLN PHE SER ALA SER ALA SER ARG n/a n/a
385 5J6H - NCA C6 H6 N2 O c1cc(cnc1)....
386 1KJV - ASN PRO ARG ALA MET GLN ALA LEU LEU n/a n/a
387 1YDP - ARG ILE ILE PRO ARG HIS LEU GLN LEU n/a n/a
388 3KYN - LYS GLY PRO PRO ALA ALA LEU THR LEU n/a n/a
389 3KYO - LYS LEU PRO ALA GLN PHE TYR ILE LEU n/a n/a
390 6J2F - ASP TYR ILE ASN THR ASN VAL LEU PRO n/a n/a
391 6J2D - ASP PHE ALA ASN THR PHE LEU PRO n/a n/a
392 6ILC - ASP PHE ALA ASN THR PHE LEU PRO n/a n/a
393 1S7X - LYS ALA VAL PHE ASN PHE ALA THR MET n/a n/a
394 6GB5 - PHE ALA PRO GLY ASN TYR PRO n/a n/a
395 6GB7 - GLU ASP ALA GLY GLY GLY GLY LEU SER LYS n/a n/a
396 1S7U - LYS ALA VAL TYR ASN PHE ALA THR MET n/a n/a
397 1S7V - LYS ALA VAL TYR ASN LEU ALA THR MET n/a n/a
398 1S7W - LYS ALA LEU TYR ASN PHE ALA THR MET n/a n/a
399 1TMC - GLU VAL ALA PRO PRO GLU TYR HIS ARG LYS n/a n/a
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ARG GLY TYR VAL TYR GLN GLY LEU; Similar ligands found: 129
No: Ligand ECFP6 Tc MDL keys Tc
1 ARG GLY TYR VAL TYR GLN GLY LEU 1 1
2 ARG GLY TYR LEU TYR GLN GLY LEU 0.844037 1
3 ARG GLY TYR VAL TYR ESC GLY LEU GAL GLA 0.642384 0.8
4 PHE LEU ARG GLY ARG ALA TYR VAL LEU 0.631579 0.982456
5 ARG VAL ALA GLN LEU GLU GLN VAL TYR ILE 0.606061 0.929825
6 ARG TYR GLY PHE VAL ALA ASN PHE 0.598485 0.932203
7 SER ARG ILE ARG ILE ARG GLY TYR VAL ARG 0.59375 0.857143
8 SER ASP TYR GLN ARG LEU 0.583333 0.929825
9 LEU TYR LEU VAL CYS GLY GLU ARG GLY PHE 0.58156 0.965517
10 LEU TYR LEU VAL CYS GLY GLU ARG GLY 0.580882 0.931035
11 LEU TYR LEU VAL CYS GLY GLU ARG VAL 0.572464 0.931035
12 PHE LEU ARG GLY ARG ALA TYR GLY LEU 0.568182 0.982456
13 ARG ARG LEU LEU ARG GLY HIS ASN GLN TYR 0.567376 0.833333
14 ARG THR PHE SER PRO THR TYR GLY LEU 0.557823 0.777778
15 GLY GLY LYS LYS ARG TYR LYS LEU 0.535433 0.931035
16 GLY GLY LYS LYS LYS TYR ARG LEU 0.535433 0.931035
17 GLY GLY ARG LYS LYS TYR LYS LEU 0.535433 0.931035
18 ASP ASN ARG LEU GLY LEU VAL TYR GLN PHE 0.528926 0.803571
19 LEU GLY TYR GLY PHE VAL ASN TYR ILE 0.526316 0.8
20 ARG ARG ILE TYR ASP LEU ILE GLU LEU 0.52518 0.883333
21 ARG PHE MET ASP TYR TRP GLU GLY LEU 0.522293 0.835821
22 LEU LEU TYR GLY PHE VAL ASN TYR VAL 0.518797 0.813559
23 GLY GLY LYS LYS LYS TYR GLN LEU 0.507937 0.827586
24 LEU LEU TYR GLY PHE VAL ASN TYR ILE 0.50365 0.8
25 MET LEU TRP GLY TYR LEU GLN TYR VAL 0.503401 0.757576
26 ALA ARG THR GLU LEU TYR ARG SER LEU 0.489209 0.854839
27 PRO GLU GLY ASP PM3 GLU GLU VAL LEU 0.488889 0.6875
28 ALA THR VAL ARG THR TYR SER CYS 0.488722 0.822581
29 ARG HIS ARG MLZ VAL LEU ARG ASP ASN TYR 0.484076 0.760563
30 TYR GLY GLY PHE LEU 0.483607 0.842105
31 GLY VAL TYR ASP GLY ARG GLU HIS THR VAL 0.480519 0.80597
32 PHE ARG TYR LEU GLY 0.476923 1
33 LEU GLU LYS ALA ARG GLY SER THR TYR 0.470588 0.857143
34 SER SER VAL VAL GLY VAL TRP TYR LEU 0.468966 0.701493
35 GLY ALA ALA ARG ALA GLU VAL TYR LEU ARG 0.466216 0.898305
36 ARG PRO MET THR TYR LYS GLY ALA LEU 0.463855 0.710526
37 GLY SER HIS LEU GLU VAL GLN GLY TYR TRP 0.460606 0.75
38 GLY ALA GLU VAL PHE TYR VAL ASP GLY ALA 0.459854 0.827586
39 SER GLN TYR TYR TYR ASN SER LEU 0.456693 0.758065
40 GLU LEU LYS ARG LYS MET ILE TYR MET 0.456376 0.84127
41 GLY GLY LYS LYS LYS TYR LYS LEU 0.456 0.827586
42 GLU LEU ARG ARG LYS MET MET TYR MET 0.453901 0.84127
43 SER LEU ARG PHE LEU TYR GLU GLY 0.453901 0.933333
44 ARG HIS ARG MLY VAL LEU ARG ASP TYR 0.451613 0.739726
45 GLU THR VAL ARG PHE GLN SER ASP 0.451389 0.816667
46 GLY ARG PHE GLN VAL THR 0.451128 0.859649
47 ARG LEU TYR GLN ASN PRO THR THR TYR ILE 0.450617 0.743243
48 ARG LEU GLN ARG ARG ARG GLU THR GLN VAL 0.450382 0.770492
49 ALA GLN ASP ILE TYR ARG ALA SER TYR 0.450331 0.870968
50 SER SER VAL ILE GLY VAL TRP TYR LEU 0.450331 0.691176
51 GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE 0.44898 0.85
52 GLY ILE LEU GLY LEU VAL PHE THR LEU 0.448529 0.716667
53 ASP VAL GLN THR GLY ARG ARG PRO TYR GLU 0.447205 0.736111
54 ASN ALA LEU LEU ARG TYR LEU LEU ASP 0.445255 0.883333
55 PHE TYR ARG ALA LEU MET 0.443662 0.9
56 GLY ALA GLU THR PHE TYR VAL ASP GLY ALA 0.443662 0.786885
57 ALA ARG THR MLY GLN THR ALA ARG TYR 0.440559 0.768116
58 GLY ILE TRP GLY PHE VAL PHE THR LEU 0.44 0.69697
59 GLU LEU ASN ARG LYS MET ILE TYR MET 0.43949 0.80303
60 ARG TYR PRO LEU THR PHE GLY TRP 0.439306 0.767123
61 TYR GLU LEU ASP GLU LYS PHE ASP ARG LEU 0.439189 0.916667
62 GLY ALA GLN THR PHE TYR VAL ASP GLY ALA 0.438849 0.8
63 GLU LEU LYS TPO GLU ARG TYR 0.436242 0.779412
64 ARG ARG ARG VAL ARG 00S 0.435484 0.762712
65 ARG ARG GLY LEU NH2 0.433628 0.77193
66 TYR ASP GLN ILE LEU 0.433071 0.741379
67 ARG GLY PHE ALA LEU M3L SER THR HIS GLY 0.430303 0.666667
68 LEU GLY GLY ALA LYS GLN ARG GLY ASP VAL 0.428571 0.762712
69 ACE ALA ARG THR GLU VAL TYR NH2 0.427536 0.881356
70 THR LYS ASN TYR LYS GLN THR SER VAL 0.426573 0.71875
71 THR ASN GLU TYR TYR VAL 0.42623 0.745763
72 TYR TYR GLU SER GLY TRP LEU 0.425676 0.727273
73 GLY ASN PHE LEU GLN SER ARG 0.425532 0.806452
74 SER SER ARG LYS GLU TYR TYR ALA 0.425373 0.913793
75 GLU GLU PHE GLY ARG ALA PHE SER PHE 0.424658 0.816667
76 GLU GLU TYR LEU GLN ALA PHE THR TYR 0.424658 0.779661
77 PHQ LEU VAL ARG TYR 0.42446 0.9
78 GLU VAL TYR GLU SER 0.424 0.758621
79 ARG GLY THR 0.423423 0.789474
80 VAL LYS VAL VAL ALA LYS LYS TYR ARG ASN 0.423358 0.852459
81 ILE GLY PRO GLY ARG ALA PHE TYR VAL 0.423313 0.823529
82 ARG ILE PRO SER TYR ARG TYR ARG TYR 0.422819 0.716216
83 TYR GLN SER LYS LEU 0.421875 0.770492
84 SER GLU LEU GLU ILE LYS ARG TYR 0.421769 0.84127
85 GLU GLN TYR LYS PHE TYR SER VAL 0.421429 0.774194
86 LEU LEU PHE GLY LYS PRO VAL TYR VAL 0.420382 0.724638
87 LEU PHE GLY TYR PRO VAL TYR VAL 0.42 0.746269
88 THR GLU ASN LEU TYR PHE GLN SER GLY THR 0.42 0.806452
89 GLN SER TYR TPO VAL 0.419847 0.661765
90 ARG MET PHE PRO ASN ALA PRO TYR LEU 0.419162 0.727273
91 ACE ILE TYR GLU SER LEU 0.418605 0.721311
92 ILE LEU GLY LYS PHE LEU HIS ARG LEU 0.418301 0.784615
93 ARG ABA VAL ILE PHE ALA ASN ILE 0.416667 0.8
94 GLU THR PHE TYR VAL ASP GLY 0.416058 0.8
95 ASN ARG PRO VAL TYR ILE PRO ARG PRO PRO 0.415584 0.742857
96 ARG PRO MET THR PHE LYS GLY ALA LEU 0.415205 0.671053
97 ARG ARG LEU PRO ILE PHE SER ARG LEU 0.414013 0.662162
98 LEU LEU PHE GLY PHE PRO VAL TYR VAL 0.412903 0.746269
99 LEU LEU PHE GLY TYR PRO VAL TYR VAL 0.412903 0.746269
100 SER LEU TYR ASN VAL VAL ALA THR LEU 0.411348 0.693548
101 PHE GLN TRP MET GLY TYR GLU LEU TRP 0.411043 0.746269
102 ARG TYR PRO LEU THR LEU GLY TRP CYS PHE 0.410811 0.746667
103 TYR HIS SEP VAL VAL ARG TYR ALA 0.410256 0.702703
104 ARG ARG ARG TRP ARG ARG LEU THR VAL 0.408163 0.761194
105 THR ARG ARG GLU THR GLN LEU 0.407692 0.770492
106 GLU ALA GLN THR ARG LEU 0.407407 0.79661
107 GLU ASN LEU TYR PHE GLN 0.407407 0.779661
108 SER LEU TYR LEU THR VAL ALA THR LEU 0.407407 0.688525
109 SER SER THR ARG GLY ILE SER GLN LEU TRP 0.406061 0.779412
110 GLU LEU ARG SER ARG TYR TRP ALA ILE 0.406061 0.797101
111 ILE GLY PRO GLY ARG ALA PHE TYR THR 0.406061 0.797101
112 MET LEU ILE TYR SER MET TRP GLY LYS 0.405882 0.684932
113 SAC ARG GLY THR GLN THR GLU 0.404412 0.741935
114 ALA GLN PHE SER ALA SER ALA SER ARG 0.404412 0.770492
115 SER LEU TYR ASN THR VAL ALA THR LEU 0.404255 0.693548
116 SER VAL TYR ASP PHE PHE VAL TRP LEU 0.403974 0.686567
117 LEU TYR ALA SER PRO GLN LEU GLU GLY PHE 0.403614 0.714286
118 THR PHE GLN ALA PSA LEU ARG GLU 0.402516 0.868852
119 ARG GLY PRO GLY CYS ALA PHE VAL THR ILE 0.402367 0.69863
120 ASP ARG VAL TYR 0.401639 0.741379
121 TYR GLY GLY PHE MET 0.401515 0.770492
122 ARG LEU TRP SER 0.40146 0.78125
123 LYS ALA VAL TYR ASN LEU ALA THR MET 0.401316 0.712121
124 SER SER LEU GLU ASN PHE ARG ALA TYR VAL 0.401235 0.887097
125 GLN VAL PRO LEU ARG PRO MET THR TYR LYS 0.40113 0.710526
126 GLU TYR LEU GLY LEU ASP VAL PRO VAL 0.4 0.705882
127 TYR VAL ASP GLY ALA 0.4 0.775862
128 ASN TYR THR PRO GLY PRO GLY THR ARG PHE 0.4 0.739726
129 SER SER ILE GLU PHE ALA ARG LEU 0.4 0.790323
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1LEK; Ligand: GLU GLN TYR LYS PHE TYR SER VAL; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 1lek.bio1) has 62 residues
No: Leader PDB Ligand Sequence Similarity
APoc FAQ
Feedback