Receptor
PDB id Resolution Class Description Source Keywords
1G5N 1.9 Å NON-ENZYME: OTHER ANNEXIN V COMPLEX WITH HEPARIN OLIGOSACCHARIDES RATTUS NORVEGICUS HELIX-BUNDLE MEMBRANE BINDING HEPARIN HEPARAN SULFATE BLCLOTTING
Ref.: ANNEXIN V--HEPARIN OLIGOSACCHARIDE COMPLEX SUGGESTS SULFATE--MEDIATED ASSEMBLY ON CELL SURFACES. STRUCTURE V. 9 57 2001
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
CA A:401;
A:402;
A:403;
A:404;
A:406;
A:407;
A:408;
A:409;
A:410;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
40.078 Ca [Ca+2...
UAP SGN IDS SGN A:801;
A:901;
Valid;
Valid;
none;
none;
submit data
1146.88 n/a [S+2]...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1G5N 1.9 Å NON-ENZYME: OTHER ANNEXIN V COMPLEX WITH HEPARIN OLIGOSACCHARIDES RATTUS NORVEGICUS HELIX-BUNDLE MEMBRANE BINDING HEPARIN HEPARAN SULFATE BLCLOTTING
Ref.: ANNEXIN V--HEPARIN OLIGOSACCHARIDE COMPLEX SUGGESTS SULFATE--MEDIATED ASSEMBLY ON CELL SURFACES. STRUCTURE V. 9 57 2001
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1256 families.
1 1A8B - GPE C5 H14 N O6 P C(CO[P@](=....
2 1A8A - GSE C6 H14 N O8 P C([C@H](CO....
3 1G5N - UAP SGN IDS SGN n/a n/a
70% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1068 families.
1 1A8B - GPE C5 H14 N O6 P C(CO[P@](=....
2 1A8A - GSE C6 H14 N O8 P C([C@H](CO....
3 1G5N - UAP SGN IDS SGN n/a n/a
50% Homology Family (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 922 families.
1 2HYU - UAP SGN IDS SGN n/a n/a
2 2HYV - UAP SGN IDS SGN IDS n/a n/a
3 1A8B - GPE C5 H14 N O6 P C(CO[P@](=....
4 1A8A - GSE C6 H14 N O8 P C([C@H](CO....
5 1G5N - UAP SGN IDS SGN n/a n/a
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: UAP SGN IDS SGN; Similar ligands found: 17
No: Ligand ECFP6 Tc MDL keys Tc
1 SGN IDS UAP SGN IDS SGN 1 1
2 SGN IDS UAP SGN 1 1
3 UAP SGN IDS SGN IDS SGN 1 1
4 UAP SGN IDS SGN 1 1
5 UAP SGN IDS SGN IDS 0.839623 1
6 SGN IDS SGN IDS 0.72381 0.967742
7 SGN IDS SGN IDS SGN 0.66087 0.9375
8 SGN IDS SGN IDS SGN IDS 0.60177 0.952381
9 IDS SGN IDS SGN IDS 0.561983 0.952381
10 IDS SGN IDS SGN IDS IDS 0.548387 0.9375
11 IDS SGN IDS SGN IDS SUS IDS SGN 0.548387 0.952381
12 SGN IDY 0.495495 0.876923
13 IDU SGN 0.491071 0.904762
14 SGN IXD 0.491071 0.904762
15 NGY BDP SGN IDS SGN BDP 0.485507 0.895522
16 SUS IDY 0.448276 0.846154
17 GNS BDP GNS IDS GNS BDP NPO 0.431655 0.810811
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1G5N; Ligand: UAP SGN IDS SGN; Similar sites found: 13
This union binding pocket(no: 1) in the query (biounit: 1g5n.bio1) has 10 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1LC3 NAD 0.009528 0.42886 1.02041
2 2GLX NDP 0.03312 0.40074 1.88679
3 2ZPT A3P 0.01769 0.43434 3.05085
4 3UR0 SVR 0.03693 0.40556 3.45912
5 1VLH PNS 0.01935 0.41813 4.62428
6 3S5W FAD 0.01677 0.4319 4.71698
7 4CNK FAD 0.03726 0.42131 4.71698
8 3ND6 ATP 0.04064 0.40915 5.26316
9 5X7Q GLC GLC GLC BGC 0.02363 0.40061 5.34591
10 1S8F GDP 0.02482 0.41821 6.77966
11 4K81 GTP 0.02838 0.41662 6.97674
12 2D5Z L35 0.03977 0.44072 36.3014
13 1TU3 GNP 0.03657 0.41459 41.7722
Pocket No.: 2; Query (leader) PDB : 1G5N; Ligand: UAP SGN IDS SGN; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 1g5n.bio1) has 8 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
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