Receptor
PDB id Resolution Class Description Source Keywords
1GEX 2.2 Å EC: 2.6.1.9 CRYSTAL STRUCTURE OF HISTIDINOL-PHOSPHATE AMINOTRANSFERASE C WITH HISTIDINOL-PHOSPHATE ESCHERICHIA COLI ALPHA/BETA-STRUCTURE AMINOTRANSFERASE PYRIDOXAL-5-prime -PHOSPHAPHOSPHORIC ACID MONO-[2-AMINO-3-(3H-IMIDAZOL-4-YL)-PROPYL]ECOMPLEX TRANSFERASE
Ref.: STRUCTURES OF ESCHERICHIA COLI HISTIDINOL-PHOSPHATE AMINOTRANSFERASE AND ITS COMPLEXES WITH HISTIDINOL-AND N-(5'-PHOSPHOPYRIDOXYL)-L-GLUTAMATE: DOUBLE SUB RECOGNITION OF THE ENZYME. BIOCHEMISTRY V. 40 4633 2001
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
PLP HSA A:413;
Valid;
none;
submit data n/a n/a n/a n/a
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1GEX 2.2 Å EC: 2.6.1.9 CRYSTAL STRUCTURE OF HISTIDINOL-PHOSPHATE AMINOTRANSFERASE C WITH HISTIDINOL-PHOSPHATE ESCHERICHIA COLI ALPHA/BETA-STRUCTURE AMINOTRANSFERASE PYRIDOXAL-5-prime -PHOSPHAPHOSPHORIC ACID MONO-[2-AMINO-3-(3H-IMIDAZOL-4-YL)-PROPYL]ECOMPLEX TRANSFERASE
Ref.: STRUCTURES OF ESCHERICHIA COLI HISTIDINOL-PHOSPHATE AMINOTRANSFERASE AND ITS COMPLEXES WITH HISTIDINOL-AND N-(5'-PHOSPHOPYRIDOXYL)-L-GLUTAMATE: DOUBLE SUB RECOGNITION OF THE ENZYME. BIOCHEMISTRY V. 40 4633 2001
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 1GEY - PPE C13 H20 N2 O9 P Cc1c(c(c(c....
2 1FG7 - PMP C8 H13 N2 O5 P Cc1c(c(c(c....
3 1GEX - PLP HSA n/a n/a
70% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 1GEY - PPE C13 H20 N2 O9 P Cc1c(c(c(c....
2 1FG7 - PMP C8 H13 N2 O5 P Cc1c(c(c(c....
3 1GEX - PLP HSA n/a n/a
50% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 3CQ5 - PMP C8 H13 N2 O5 P Cc1c(c(c(c....
2 1GEY - PPE C13 H20 N2 O9 P Cc1c(c(c(c....
3 1FG7 - PMP C8 H13 N2 O5 P Cc1c(c(c(c....
4 1GEX - PLP HSA n/a n/a
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: PLP HSA; Similar ligands found: 0
No: Ligand ECFP6 Tc MDL keys Tc
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1GEX; Ligand: PLP HSA; Similar sites found with APoc: 4
This union binding pocket(no: 1) in the query (biounit: 1gex.bio1) has 26 residues
No: Leader PDB Ligand Sequence Similarity
1 5VEQ PMP 23.8764
2 4FL0 PLP 23.8764
3 2X5D PLP 30.8989
4 4R5Z PMP 39.782
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