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Receptor
PDB id Resolution Class Description Source Keywords
1GTE 1.65 Å EC: 1.3.1.2 DIHYDROPYRIMIDINE DEHYDROGENASE (DPD) FROM PIG, BINARY COMPL IODOURACIL SUS SCROFA ELECTRON TRANSFER FLAVIN IRON-SULFUR CLUSTERS PYRIMIDINE CATABOLISM 5-FLUOROURACIL DEGRADATION OXIDOREDUCTASE
Ref.: CRYSTAL STRUCTURE OF THE PRODUCTIVE TERNARY COMPLEX DIHYDROPYRIMIDINE DEHYDROGENASE WITH NADPH AND 5-IO IMPLICATIONS FOR MECHANISM OF INHIBITION AND ELECTR TRANSFER J.BIOL.CHEM. V. 277 13155 2002
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
FAD A:1031;
B:1031;
C:1031;
D:1031;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
submit data
785.55 C27 H33 N9 O15 P2 Cc1cc...
FMN A:1030;
B:1030;
C:1030;
D:1030;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
submit data
456.344 C17 H21 N4 O9 P Cc1cc...
IUR A:1034;
B:1034;
C:1034;
D:1034;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
submit data
237.983 C4 H3 I N2 O2 C1=C(...
SF4 A:1026;
A:1027;
A:1028;
A:1029;
B:1026;
B:1027;
B:1028;
B:1029;
C:1026;
C:1027;
C:1028;
C:1029;
D:1026;
D:1027;
D:1028;
D:1029;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
351.64 Fe4 S4 [S]12...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1GTE 1.65 Å EC: 1.3.1.2 DIHYDROPYRIMIDINE DEHYDROGENASE (DPD) FROM PIG, BINARY COMPL IODOURACIL SUS SCROFA ELECTRON TRANSFER FLAVIN IRON-SULFUR CLUSTERS PYRIMIDINE CATABOLISM 5-FLUOROURACIL DEGRADATION OXIDOREDUCTASE
Ref.: CRYSTAL STRUCTURE OF THE PRODUCTIVE TERNARY COMPLEX DIHYDROPYRIMIDINE DEHYDROGENASE WITH NADPH AND 5-IO IMPLICATIONS FOR MECHANISM OF INHIBITION AND ELECTR TRANSFER J.BIOL.CHEM. V. 277 13155 2002
Members (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 1GTE - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
2 1H7W - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
3 1GTH - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
4 1H7X - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
70% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 1GTE - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
2 1H7W - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
3 1GTH - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
4 1H7X - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
50% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 1GTE - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
2 1H7W - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
3 1GTH - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
4 1H7X - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: FAD; Similar ligands found: 128
No: Ligand ECFP6 Tc MDL keys Tc
1 FAD 1 1
2 FAS 1 1
3 FAY 0.859259 0.9875
4 RFL 0.852941 0.963855
5 6FA 0.794118 0.987654
6 FAE 0.751773 0.987654
7 SFD 0.651007 0.860215
8 FDA 0.641892 0.906977
9 FNK 0.602564 0.876405
10 62F 0.572327 0.939024
11 F2N 0.566265 0.886364
12 FMN 0.543307 0.876543
13 FA9 0.526316 0.939759
14 6YU 0.516304 0.860215
15 P6G FDA 0.511628 0.908046
16 FAD NBT 0.508876 0.83871
17 A2D 0.504065 0.875
18 P5F 0.491329 0.941176
19 FAD CNX 0.488506 0.8125
20 AR6 0.488372 0.851852
21 APR 0.488372 0.851852
22 AGS 0.484615 0.811765
23 SAP 0.484615 0.811765
24 M33 0.484375 0.864198
25 BA3 0.484127 0.875
26 HEJ 0.48062 0.851852
27 ATP 0.48062 0.851852
28 ADP 0.480315 0.851852
29 B4P 0.480315 0.875
30 AP5 0.480315 0.875
31 ANP 0.477273 0.831325
32 AQP 0.476923 0.851852
33 5FA 0.476923 0.851852
34 48N 0.469388 0.902439
35 OAD 0.467626 0.876543
36 9X8 0.467626 0.833333
37 FAD NBA 0.467033 0.793814
38 GTA 0.465753 0.892857
39 AN2 0.465116 0.841463
40 AT4 0.465116 0.821429
41 AD9 0.462121 0.831325
42 3OD 0.460993 0.876543
43 RBF 0.460938 0.790123
44 FB0 0.460606 0.835165
45 139 0.460526 0.858824
46 AP0 0.46 0.835294
47 A22 0.459854 0.864198
48 ACP 0.458015 0.853659
49 8QN 0.456522 0.864198
50 PRX 0.454545 0.831325
51 A3R 0.453237 0.86747
52 A1R 0.453237 0.86747
53 G3A 0.452055 0.902439
54 T5A 0.45098 0.872093
55 G5P 0.44898 0.902439
56 ATF 0.448529 0.821429
57 50T 0.44697 0.819277
58 6YZ 0.445255 0.853659
59 ACQ 0.444444 0.853659
60 CNV FAD 0.443182 0.917647
61 ADQ 0.442857 0.853659
62 PAJ 0.442857 0.847059
63 5AL 0.441176 0.864198
64 ADX 0.439394 0.775281
65 CA0 0.439394 0.853659
66 A4P 0.437909 0.831461
67 25L 0.4375 0.864198
68 P33 FDA 0.436464 0.817204
69 5SV 0.435714 0.793103
70 OMR 0.434211 0.818182
71 TXE 0.434211 0.890244
72 ABM 0.434109 0.829268
73 A 0.433071 0.82716
74 AMP 0.433071 0.82716
75 4AD 0.432624 0.855422
76 ADJ 0.432258 0.818182
77 B5M 0.431507 0.878049
78 B5Y 0.431507 0.878049
79 BIS 0.430556 0.802326
80 SRA 0.429688 0.788235
81 AFH 0.42953 0.825581
82 NXX 0.427632 0.865854
83 DND 0.427632 0.865854
84 UP5 0.427632 0.878049
85 6V0 0.427632 0.857143
86 TXD 0.427632 0.890244
87 DQV 0.426667 0.8875
88 SRP 0.42446 0.843373
89 PR8 0.423611 0.837209
90 T99 0.423358 0.821429
91 TAT 0.423358 0.821429
92 AMO 0.422535 0.865854
93 TXA 0.42069 0.865854
94 FYA 0.42069 0.864198
95 PTJ 0.42069 0.835294
96 CNA 0.420382 0.865854
97 00A 0.41958 0.823529
98 AHX 0.41958 0.835294
99 MAP 0.41844 0.811765
100 NAI 0.418301 0.845238
101 AU1 0.41791 0.831325
102 A12 0.416667 0.843373
103 AP2 0.416667 0.843373
104 25A 0.415493 0.851852
105 9ZA 0.415493 0.845238
106 9ZD 0.415493 0.845238
107 COD 0.415094 0.842697
108 4TC 0.412903 0.879518
109 APC 0.411765 0.843373
110 ME8 0.410959 0.806818
111 1ZZ 0.410959 0.806818
112 NB8 0.410959 0.835294
113 4UW 0.409091 0.825581
114 NAX 0.409091 0.837209
115 F2R 0.408805 0.850575
116 RBY 0.408759 0.843373
117 ADV 0.408759 0.843373
118 P1H 0.405882 0.818182
119 OOB 0.405594 0.864198
120 LAD 0.40411 0.825581
121 A A 0.40411 0.829268
122 UPA 0.403846 0.86747
123 4UU 0.401316 0.833333
124 GA7 0.401316 0.865854
125 A3D 0.401235 0.876543
126 80F 0.401235 0.808989
127 XAH 0.4 0.806818
128 DLL 0.4 0.864198
Ligand no: 2; Ligand: FMN; Similar ligands found: 15
No: Ligand ECFP6 Tc MDL keys Tc
1 FMN 1 1
2 RBF 0.75641 0.876712
3 RS3 0.571429 0.831169
4 FAD 0.543307 0.876543
5 FAS 0.543307 0.876543
6 FAE 0.539062 0.865854
7 LFN 0.475 0.643836
8 C3F 0.473684 0.74359
9 CF4 0.463918 0.734177
10 FAY 0.446043 0.864198
11 FNR 0.444444 0.909091
12 RFL 0.442857 0.845238
13 4LS 0.411215 0.875
14 1VY 0.406593 0.769231
15 DLZ 0.404494 0.782051
Ligand no: 3; Ligand: IUR; Similar ligands found: 7
No: Ligand ECFP6 Tc MDL keys Tc
1 IUR 1 1
2 TDR 0.483871 0.860465
3 URF 0.451613 0.952381
4 WBU 0.451613 0.804348
5 5UC 0.4375 0.952381
6 5NU 0.428571 0.649123
7 FYU 0.4 0.860465
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1GTE; Ligand: IUR; Similar sites found with APoc: 248
This union binding pocket(no: 1) in the query (biounit: 1gte.bio1) has 36 residues
No: Leader PDB Ligand Sequence Similarity
1 2OG2 MLI 1.39276
2 2I6A 5I5 1.44928
3 2FYF PLP 1.50754
4 4FL0 PLP 1.53509
5 1VCO GLN 1.63636
6 3B9Q MLI 1.65563
7 4XPQ FUL 1.66667
8 3ZOK GLY 1.85185
9 1GQ2 OXL 1.98198
10 3C8F MT2 2.04082
11 6BKA FMN 2.13904
12 1FDJ 2FP 2.20386
13 1FDJ 13P 2.20386
14 3EXS 5RP 2.26244
15 4QNW FMN 2.29592
16 4RW3 IPD 2.31788
17 1POT SPD 2.46154
18 4N02 FNR 2.52101
19 4L8F MTX 2.5641
20 4CW5 FMN 2.64317
21 2Q3R FMN 2.68817
22 4BI7 PGA 2.72374
23 5AVF TAU 2.72374
24 1DJN FMN 2.74348
25 1PMO PLR 2.7897
26 2QS8 MET 2.87081
27 4M5P FMN 2.9484
28 4GV8 DUP 2.95858
29 4XDY HIO 2.95858
30 4PMZ BXP 2.9703
31 3T7S SAM 2.98507
32 4M26 AKG 3.02198
33 1QMG DMV 3.05344
34 4A3U FMN 3.07263
35 3IP6 PRO 3.08989
36 3GAY P6T 3.09598
37 1TE2 PGA 3.09735
38 2QUN FUD 3.10345
39 6A6A DAL 3.11111
40 5LY1 PPI 3.14961
41 4JIQ 1L5 3.18302
42 4JIQ FMN 3.18302
43 1LYX PGA 3.22581
44 2DWU DGL 3.26087
45 5E4R 40E 3.26531
46 3UXM 0DN 3.31754
47 5D85 FLC 3.37423
48 5D85 P1T 3.37423
49 1QFT HSM 3.42857
50 4XFM THE 3.44828
51 1KBI FMN 3.5225
52 1KBI PYR 3.5225
53 3N9R TD3 3.58306
54 3C56 PH4 3.58306
55 4YMZ 13P 3.58566
56 4AF0 IMP 3.59712
57 5EYW PGA 3.61446
58 1BWV CAP 3.62319
59 5VJE GOS 3.63128
60 2AJ4 GLA 3.64964
61 2C6Q IMP 3.7037
62 1EXF GLY 3.71901
63 1SQS TLA 3.71901
64 6BFG FMN 3.7594
65 2ZRU FMN 3.80435
66 6F90 MVL 3.85144
67 2DW7 SRT 3.85604
68 4IXH IMP 3.87812
69 4JLS 3ZE 3.94737
70 5W3Y ACO 3.97727
71 5CSS G3P 3.9823
72 1OFD AKG 4
73 1OFD FMN 4
74 2D2F ADP 4
75 3VKC FPQ 4.1958
76 4OHB 5HM 4.21053
77 4WOH 4NP 4.21687
78 5N9Z CAP 4.31655
79 2OEM 1AE 4.35835
80 1KBJ FMN 4.36893
81 1A5Z FBP 4.38871
82 1SW0 PGA 4.43548
83 4Q4K FMN 4.48179
84 3QPB URA 4.60993
85 4XDZ 40E 4.66472
86 1OX5 1PR 4.68468
87 2OFW ADX 4.80769
88 5EJL C2E 4.83871
89 1M5W DXP 4.93827
90 5OYA CAP 5.03597
91 2G30 ALA ALA PHE 5.03876
92 1MV8 SUC 5.04587
93 4I9A NCN 5.20833
94 1VAY AZA 5.22648
95 3TAO PGH 5.24345
96 2FJK 13P 5.2459
97 1X8X TYR 5.2795
98 2H8Z 8CM 5.29248
99 2H8Z FMN 5.29248
100 3SZB I1E 5.33049
101 1BGV GLU 5.34521
102 1JCM 137 5.40541
103 2FLI DX5 5.45455
104 2GJN NIS 5.4878
105 2GJN FMN 5.4878
106 1IGW PYR 5.52995
107 1OCU PIB 5.55556
108 5XNC N4P 5.66038
109 1W8S FBP 5.70342
110 4I9B NAD 5.80271
111 2X5F PLP 5.81395
112 2R14 FMN 5.83554
113 2R14 TXD 5.83554
114 2RDT FMN 5.94315
115 2RDT 2RD 5.94315
116 4B16 NAG 6.01504
117 5GVH FMN 6.05096
118 3GLC R5P 6.1017
119 3ZX4 2M8 6.17761
120 5OCS FMN 6.19946
121 1O9W NAG 6.21469
122 6HKE MLT 6.28931
123 3R4S SIA 6.32054
124 3ATY FMN 6.33245
125 2F6U CIT 6.41026
126 2V6A CAP 6.42857
127 2V67 CAP 6.42857
128 2V63 CAP 6.42857
129 2V68 CAP 6.42857
130 2VDH CAP 6.42857
131 4TMC FMN 6.45161
132 4TMC HBA 6.45161
133 2HSA FMN 6.46766
134 6BVE PGA 6.53061
135 5D3X 4IP 6.58683
136 5JCJ 6JM 6.59722
137 1UZD CAP 6.71642
138 3FYP PEP 6.78571
139 2GOU FMN 6.84932
140 4UBT 3G6 7.01754
141 4NAE 1GP 7.11111
142 3NZ1 3NY 7.27969
143 1PS9 FMN 7.45156
144 1OYB HBA 7.5
145 1OYB FMN 7.5
146 4EWN 0VR 7.50988
147 2BTM PGA 7.53968
148 3KRU FMN 7.58017
149 5TCI MLI 7.6087
150 3UW4 MAA CHG PRO 0DQ 7.6087
151 1VYP FMN 7.69231
152 1VYP TNF 7.69231
153 1RM8 BAT 7.69231
154 3PDB PMP 7.98005
155 1PTR PRB 8
156 2R00 OEG 8.03571
157 2YPI PGA 8.09717
158 3RZ3 U94 8.19672
159 4JGP PYR 8.29493
160 5AHN IMP 8.38446
161 5J32 IPM 8.43672
162 2Q3O FMN 8.4399
163 4FGC PQ0 8.48485
164 1U08 PLP 8.54922
165 4P5E N6P 8.55263
166 3L8G GMB 8.55615
167 5A5W GUO 8.69565
168 1Q6O LG6 8.7963
169 1QPR PPC 8.80282
170 1WUW SER 8.88889
171 1P4C FMN 8.94737
172 2NLI FMN 8.96739
173 2NLI LAC 8.96739
174 1M26 GAL A2G 9.02256
175 1TB3 FMN 9.09091
176 1RBL CAP 9.17431
177 1WDD CAP 9.375
178 1GVF PGH 9.44056
179 6DND PLP 9.73236
180 2JFV FLC 9.96564
181 1TZJ A3B 10.0592
182 3OVR 5SP 10.0877
183 1UJP CIT 10.3321
184 2XYA 7L4 10.4396
185 1QDS PGA 10.757
186 4X5S AZM 10.7759
187 3EW2 BTN 11.1111
188 6DVH FMN 11.1675
189 1ICP FMN 11.1702
190 5AHM IMP 11.5
191 3QH2 3NM 11.7647
192 2VPY PCI 11.8577
193 3A75 GLU 11.8919
194 3P7N FMN 12.0155
195 2Z6I FMN 12.3494
196 1TV5 FMN 12.4153
197 1TV5 ORO 12.4153
198 3BW2 FMN 12.4661
199 2Z6J FMN 12.6506
200 1IR2 CAP 12.8571
201 3HF3 FMN 12.894
202 2AGC DAO 12.963
203 4PU6 ASP 12.9771
204 1Z44 FMN 13.0178
205 1Z48 FMN 13.0178
206 1Z42 FMN 13.0178
207 1Z41 FMN 13.0178
208 4JEJ 1GP 13.1148
209 3B0P FMN 13.4286
210 1UZH CAP 13.9344
211 2TPS TPS 14.5374
212 3AXK NDP 14.7287
213 1VHN FMN 14.7799
214 4XP7 FNR 15.0289
215 6FA4 D1W 15.0289
216 3CM2 X23 15.3846
217 3W9Z FMN 15.528
218 1TRD PGH 16
219 4UTU LRY 18.3406
220 4UTW RFW 18.3406
221 3CTL S6P 18.6147
222 2HK9 SKM 19.2727
223 3ZJX BOG 19.3772
224 1AL8 FMN 19.4986
225 1AL8 DHP 19.4986
226 5H9O GLC 21.5909
227 4WZH FMN 23.3429
228 1VKF CIT 23.4043
229 3MJY IJZ 23.6994
230 3MJY FMN 23.6994
231 1F76 FMN 25.8929
232 1F76 ORO 25.8929
233 3C3N FMN 27.5641
234 3OIX FMN 28.9855
235 4ORM FMN 30.6733
236 4ORM ORO 30.6733
237 4ORM 2V6 30.6733
238 4IGH ORO 35.2151
239 4IGH 1EA 35.2151
240 4IGH FMN 35.2151
241 1UUO ORO 35.7527
242 1UUO BRF 35.7527
243 1UUO FMN 35.7527
244 1OVD ORO 42.4437
245 1OVD FMN 42.4437
246 5XFV FMN 42.515
247 1EP2 FMN 47.2669
248 1EP2 ORO 47.2669
Pocket No.: 2; Query (leader) PDB : 1GTE; Ligand: FAD; Similar sites found with APoc: 982
This union binding pocket(no: 2) in the query (biounit: 1gte.bio1) has 56 residues
No: Leader PDB Ligand Sequence Similarity
1 1X87 NAD 1.08893
2 4K5S FAD 1.1194
3 4K5S PM0 1.1194
4 3K7M FAD 1.16009
5 2I6A 5I5 1.44928
6 1GZ4 ATP 1.45191
7 4KRG SAH 1.50215
8 1KOL NAD 1.50754
9 5GT9 NAP 1.52091
10 3X0D SAH 1.52672
11 3R7F CP 1.64474
12 3AYI HCI 1.66436
13 3AYI FAD 1.66436
14 1OBB NAD 1.66667
15 3N29 GOL 1.67464
16 4EUE NAI 1.67464
17 4MIG G3F 1.69753
18 3H9E NAD 1.7341
19 2WET FAD 1.76125
20 1I9G SAM 1.78571
21 3L4S NAD 1.78571
22 3L4S 3PG 1.78571
23 1Q19 SSC 1.78926
24 4Z0H NAD 1.79641
25 4PLG OXM 1.79641
26 4PLG NAI 1.79641
27 1P9B GDP 1.80995
28 3PT9 SAH 1.83276
29 5D4V SAH 1.86567
30 3QOX SAH 1.87793
31 1EZ4 NAD 1.88679
32 4LWP SAH 1.90217
33 4AZW SAM 1.91083
34 4KVL PLM 1.93237
35 2QQF A1R 1.94805
36 2X6T NAP 1.96078
37 5FJN FAD 1.97368
38 5FJN BE2 1.97368
39 1GQ2 NAP 1.98198
40 5U0L 8YP 2.01207
41 5JJR SAH 2.01794
42 1LJ8 NAD 2.0284
43 1M2W NAD 2.0284
44 2AQJ TRP 2.04461
45 2AQJ FAD 2.04461
46 5EB4 FAD 2.06767
47 5VN0 FAD 2.12355
48 5VN0 NAI 2.12355
49 3NTD FAD 2.12389
50 6BWL NAD 2.13415
51 5L53 NAP 2.16049
52 3GWZ SAH 2.16802
53 1COY FAD 2.16963
54 1COY AND 2.16963
55 1GR0 NAD 2.17984
56 5I39 FAD 2.20588
57 2CDU ADP 2.21239
58 2CDU FAD 2.21239
59 3DAG FEG 2.23464
60 1EQ2 NAP 2.25806
61 4OM8 NAD 2.26537
62 1DIG NAP 2.28758
63 1Z45 NAD 2.28898
64 1KJ8 GAR 2.30179
65 5KOX FAD 2.31092
66 5KOX RFP 2.31092
67 4XQC NAD 2.31579
68 4XQC 13D 2.31579
69 5OVL NAP 2.33333
70 4ODT GP1 Z9M 2.33645
71 4XFR CIT 2.34192
72 3GD4 NAD 2.34834
73 3GD4 FAD 2.34834
74 2ZXI FAD 2.35479
75 4HA6 FAD 2.3622
76 2XVF FAD 2.37069
77 1PN0 IPH 2.40601
78 1PN0 FAD 2.40601
79 3U31 NAD 2.41379
80 1VKO NAD 2.42086
81 4Z24 FAD 2.45399
82 5JAQ NAI 2.46305
83 3FG2 FAD 2.47525
84 3LKZ SFG 2.49221
85 3GDN HBX 2.4952
86 3GDN FAD 2.4952
87 1H2B NAJ 2.50696
88 4CJX NAP 2.50784
89 4HXY NDP 2.51142
90 5DNK SAH 2.52708
91 1BDB NAD 2.52708
92 4EIP FAD 2.55009
93 4EIP K2C 2.55009
94 4CNK FAD 2.55754
95 3GF4 FAD 2.5641
96 3GF4 UPG 2.5641
97 5LOG SAH 2.57511
98 3S5W FAD 2.59179
99 3S5W NAP 2.59179
100 4B63 NAP 2.59481
101 4B63 FAD 2.59481
102 4B63 ORN 2.59481
103 5ERG SAM 2.61097
104 1D4D FAD 2.62238
105 3C6K SPD 2.62467
106 3C6K MTA 2.62467
107 1H5Q NAP 2.64151
108 5TTJ FAD 2.65306
109 5MPT SAH 2.657
110 4FL3 ANP 2.67717
111 2NPX FAD 2.68456
112 2NPX NAD 2.68456
113 1G60 SAM 2.69231
114 1DSS NAD 2.7027
115 6F5W KG1 2.71003
116 1J0X NAD 2.71084
117 5DF1 NAP 2.71739
118 5DF1 58X 2.71739
119 3ICT ADP 2.72109
120 3ICS ADP 2.72109
121 4YCA NDP 2.72109
122 3ICR FAD 2.72109
123 3ICS FAD 2.72109
124 3ICT FAD 2.72109
125 3KLL MAL 2.73171
126 1GEG NAD 2.73438
127 1DJN ADP 2.74348
128 3RJ5 NAD 2.75591
129 3NJ4 NAD 2.75862
130 1GY8 NAD 2.77078
131 5UAO FAD 2.77264
132 2JHP SAH 2.79503
133 4NBU NAI 2.8
134 2XVE FAD 2.80172
135 2VVL FAD 2.82828
136 2VVM FAD 2.82828
137 2FK8 SAM 2.83019
138 6ECU SAH 2.8481
139 2C7G FAD 2.85088
140 2C7G ODP 2.85088
141 2NVK NAP 2.86885
142 2NVK FAD 2.86885
143 1IM8 SAI 2.86885
144 5CAE COA 2.8754
145 2DFV NAD 2.88184
146 5MQ6 NDP 2.90076
147 1LLU NAD 2.92398
148 4FZV SAM 2.92887
149 3CB2 GDP 2.94737
150 4D04 FAD 2.95203
151 4D04 NAP 2.95203
152 4XDY NAI 2.95858
153 2PX8 SAH 2.97398
154 1O0S NAI 2.97521
155 5XHA FRU 2.97521
156 2RGH FAD 2.97723
157 1ODJ GMP 2.97872
158 3T7S SAM 2.98507
159 5ULP KB1 2.98507
160 2R4J 13P 2.99401
161 2R4J FAD 2.99401
162 1VL8 NAP 2.99625
163 5BJX UDP 3.00546
164 5BJX NAD 3.00546
165 3G2O SAM 3.01003
166 5HS2 CTP 3.01724
167 4D7E FAD 3.0303
168 1SQF SAM 3.0303
169 4USR FAD 3.04709
170 5U5G NAP 3.05085
171 1QMG APX 3.05344
172 6B92 SAH 3.06122
173 4DPL NAP 3.06407
174 5G6U TRP 3.06513
175 5H5O PCG 3.10078
176 6ECT SAM 3.11526
177 4AT0 FAD 3.13725
178 5WGR FAD 3.14843
179 5YAP 8S0 3.15789
180 5YAP NAI 3.15789
181 5GWX SAM 3.16901
182 5GWX SAR 3.16901
183 6FP4 FAD 3.17726
184 6FP4 E1T 3.17726
185 1E3I CXF 3.19149
186 4RQU NAD 3.2
187 6F97 FAD 3.20151
188 2EWM NAD 3.21285
189 5MBX SP5 3.21932
190 5MBX FAD 3.21932
191 1Q9I TEO 3.21951
192 1Q9I FAD 3.21951
193 3K5I AIR 3.22581
194 4TXI FAD 3.25203
195 3QVP FAD 3.25901
196 4L8V NAP 3.2641
197 5E4R NAP 3.26531
198 5XVH NAP 3.26797
199 1HDR NAD 3.27869
200 2BD0 NAP 3.27869
201 4XB2 NDP 3.28358
202 4XB2 HSE 3.28358
203 2V6G NAP 3.2967
204 4B4U NAP 3.30033
205 4BJZ FAD 3.30189
206 4BJZ P3A 3.30189
207 1UAY ADN 3.30579
208 2EFX NFA 3.30579
209 4RF2 NAP 3.30882
210 3NT6 FAD 3.3101
211 3NTA FAD 3.3101
212 3A25 SAM 3.32226
213 6BQ6 TER 3.32326
214 4PIV NDP 3.33333
215 2HNK SAH 3.34728
216 1IY8 NAD 3.37079
217 3L9W GSH 3.38983
218 3L9W AMP 3.38983
219 1XCL SAH 3.40426
220 1JSH SIA GAL 3.40909
221 3DMH SAM 3.41207
222 3DMH GMP 3.41207
223 2O4C NAD 3.42105
224 3T31 FAD 3.43249
225 3T31 DCQ 3.43249
226 3B1F NAD 3.44828
227 1NW5 SAM 3.44828
228 2RAB NAD 3.45572
229 2RAB FAD 3.45572
230 1WP4 NDP 3.46021
231 2CVZ NDP 3.46021
232 4YT4 FE9 3.46667
233 1Y8Q ATP 3.46821
234 2BHZ MAL 3.48837
235 5YU3 NAD 3.48837
236 5YU3 PRO 3.48837
237 3UCL NAP 3.4904
238 3UCL CYH 3.4904
239 3UCL FAD 3.4904
240 4N49 SAM 3.50467
241 3WUR O4B 3.50877
242 4FWE FAD 3.51759
243 1XTP SAI 3.54331
244 2UZ1 TPP 3.5524
245 5ZW3 SAH 3.55556
246 4DMG SAM 3.56234
247 5AHO TLA 3.57143
248 5DN9 NAD 3.57143
249 6GFK SAH 3.58566
250 3DUW SAH 3.58744
251 6AIN FAD 3.58852
252 4AF0 MOA 3.59712
253 4AF0 IMP 3.59712
254 6EK3 OUL 3.61991
255 1O6Z NAD 3.63036
256 4ONQ SFG 3.64146
257 3S1S SAH 3.64465
258 1L3I SAH 3.64583
259 4YKG NAD 3.64683
260 4YKG FAD 3.64683
261 4MCC 21X 3.65854
262 6A3J NAI 3.65854
263 1RYI GOA 3.66492
264 1RYI FAD 3.66492
265 5TXR PLP 3.66599
266 1VI2 NAD 3.66667
267 2AWN ADP 3.67454
268 3A27 SAM 3.67647
269 3JWH SAH 3.68664
270 3D3W NAP 3.68852
271 1NYT NAP 3.69004
272 5HJM MTA 3.69318
273 1NAA 6FA 3.69686
274 1NAA ABL 3.69686
275 1QO8 FAD 3.71025
276 2VHW NAI 3.71353
277 5UR0 NAD 3.72493
278 1VJT NAD 3.72671
279 5Y8L HUI 3.72881
280 5Y8L NAD 3.72881
281 1X14 NAD 3.74065
282 2DKH FAD 3.75587
283 2DKH 3HB 3.75587
284 4C4A SAH 3.75723
285 6FHO FAD 3.7594
286 1GET NAP 3.77778
287 1GET FAD 3.77778
288 3HDY FDA 3.77834
289 3HDY FAD 3.77834
290 3HDY GDU 3.77834
291 4M37 SAH 3.79009
292 2YYY NAP 3.79009
293 6C4M NAP 3.79747
294 2QA1 FAD 3.8
295 1ELI PYC 3.80488
296 1NPD NAD 3.81944
297 6D6Y SAH 3.82409
298 3ABI NAD 3.83562
299 3W9F I3P 3.84615
300 4JK3 NAD 3.861
301 4E70 N7I 3.86598
302 5AOV NAP 3.86905
303 4GKV NAD 3.86905
304 5FPE 3TR 3.87597
305 2EFJ SAH 3.90625
306 1RKX NAD 3.92157
307 1U2Z SAH 3.9261
308 1GAD NAD 3.93939
309 5L4L NAP 3.94737
310 3ORF NAD 3.98406
311 3Q9T FAY 3.98614
312 3GFB NAD 4
313 2JJQ SAH 4
314 2D2F ADP 4
315 1XDS SAM 4.01069
316 3AXB PRO 4.01786
317 3AXB FAD 4.01786
318 1P1C SAH 4.0201
319 2BRY FAD 4.02414
320 5ZYN FAD 4.03397
321 3ZNN 4WL 4.03458
322 3ZNN FAD 4.03458
323 1JQ3 AAT 4.05405
324 2B4R AES 4.05797
325 2B4R NAD 4.05797
326 3G5S FAD 4.06321
327 6GNC FAD 4.08163
328 3HGM ATP 4.08163
329 4J36 FAD 4.09639
330 4J36 1HR 4.09639
331 1ZH8 NAP 4.11765
332 2VWT PYR 4.11985
333 5YB7 ORN 4.13793
334 5YB7 FAD 4.13793
335 3V1Y NAD 4.1543
336 5X20 NAD 4.16667
337 3CIF NAD 4.17827
338 3CIF G3H 4.17827
339 2JL1 NAP 4.18118
340 2VYN NAD 4.19162
341 6CEP NAD 4.19162
342 6CEP OXM 4.19162
343 1PL6 NAD 4.21348
344 1PL6 572 4.21348
345 3UOY FAD 4.22018
346 3UOY NAP 4.22018
347 1NV8 MEQ 4.22535
348 1NV8 SAM 4.22535
349 1NJR XYL 4.22535
350 5Y77 FAD 4.22833
351 4Y9D NAI 4.2623
352 1RSG FAD 4.26357
353 5X9D 80F 4.27632
354 1YY5 FAD 4.2885
355 4M52 FAD 4.29185
356 4M52 M52 4.29185
357 2JB2 FAD 4.29448
358 2JB2 PHE 4.29448
359 2A8X FAD 4.31034
360 1REO FAD 4.32099
361 5MZI FAD 4.33839
362 5MZI FYK 4.33839
363 4C3Y FAD 4.33962
364 4C3Y ANB 4.33962
365 1J5P NAD 4.34783
366 5FA8 SAM 4.34783
367 4DA6 GA2 4.34783
368 2A92 NAI 4.36137
369 5K4W NAI 4.36137
370 5K4W THR 4.36137
371 5U8U FAD 4.3659
372 1LK7 DER 4.36681
373 3SAO DBH 4.375
374 1MXI SAH 4.375
375 2HQM FAD 4.38413
376 1A5Z NAD 4.38871
377 2IVD FAD 4.39331
378 3LU1 NAD 4.3956
379 5A1T NAI 4.39883
380 1R18 SAH 4.40529
381 1VE3 SAM 4.40529
382 1C0I FAD 4.40771
383 1C0I BE2 4.40771
384 1IZC PYR 4.42478
385 1GPE FAD 4.4293
386 4REP FAD 4.44444
387 1U8X NAD 4.44915
388 5FUB SAH 4.45104
389 2GMH FAD 4.45205
390 1VL0 NAI 4.45205
391 2JAH NDP 4.45344
392 6EL3 NAP 4.46194
393 2B56 U5P 4.48718
394 1UWK NAD 4.48833
395 1UWK URO 4.48833
396 3E1T FAD 4.49219
397 1BW9 NAD 4.49438
398 1BXG NAD 4.49438
399 6DUB SAH 4.5045
400 1C1X NAD 4.50704
401 1FL2 FAD 4.51613
402 1HYH NAD 4.53074
403 3OZ2 FAD 4.53401
404 5TS5 FAD 4.54545
405 1I36 NAP 4.54545
406 3V1U NAD 4.54545
407 1YQZ FAD 4.56621
408 1PJS NAD 4.59519
409 3NOJ PYR 4.62185
410 3U4C NDP 4.62633
411 1KNR FAD 4.62963
412 4OPC PGT 4.63576
413 4OPC FDA 4.63576
414 2PWY SAH 4.65116
415 2YVF FAD 4.65686
416 2YVF NAD 4.65686
417 4XDZ NDP 4.66472
418 1FK8 NAD 4.66926
419 5GUD NDP 4.67091
420 2BGM NAJ 4.67626
421 5T96 79J 4.67836
422 1QD0 RR6 4.6875
423 5THZ SAH 4.69136
424 4USQ FAD 4.70914
425 4MP8 NAD 4.71976
426 4MP8 MLI 4.71976
427 4J1Q NDP 4.74138
428 1TDF NAP 4.74684
429 1TDF FAD 4.74684
430 4K7O EKZ 4.7619
431 3VSE SAH 4.77387
432 4BVA NDP 4.77612
433 6F3M NAD 4.78261
434 1BXK NAD 4.78873
435 1YS4 NAP 4.80226
436 5KKA 6V0 4.80769
437 3KO8 NAD 4.80769
438 1V59 NAD 4.81172
439 1V59 FAD 4.81172
440 1GV0 NAD 4.83871
441 1GUZ NAD 4.83871
442 2EG5 SAH 4.83871
443 2PZM UDP 4.84848
444 2PZM NAD 4.84848
445 2IZ1 ATR 4.85232
446 5NII FAD 4.85437
447 3NUG NAD 4.8583
448 2JAP NDP 4.8583
449 5X68 FAD 4.85933
450 5BW4 SAM 4.86891
451 1ZBQ NAD 4.89297
452 5G4L NDP 4.8951
453 5NA1 FAD 4.90196
454 4AP3 FAD 4.91803
455 4AP3 NAP 4.91803
456 4ZGS NAD 4.92228
457 1YJQ NAP 4.9505
458 1SAY PYR 4.98615
459 1O94 ADP 5
460 2F1K NAP 5.01792
461 1XG5 NAP 5.01792
462 3SJU NDP 5.01792
463 2IID FAD 5.02008
464 2IID PHE 5.02008
465 1M0S CIT 5.02283
466 2XVM SAH 5.02513
467 4IV9 FAD 5.02693
468 1UP7 NAD 5.03597
469 1MUU NAD 5.04587
470 1MV8 NAD 5.04587
471 4NBW NAD 5.05837
472 3LXD FAD 5.06024
473 3E3U NVC 5.07614
474 1H82 GZZ 5.08475
475 1H82 FAD 5.08475
476 4O0L NDP 5.09091
477 6ER9 FAD 5.10018
478 6ER9 NAP 5.10018
479 1LC3 NAD 5.10204
480 1J49 NAD 5.1051
481 6C4T NA7 5.11111
482 1V6A TRE 5.12048
483 6C4N NAP 5.12249
484 5E9W SAH 5.12821
485 1KEV NDP 5.12821
486 5OC1 FAD 5.13274
487 4PLT NAI 5.13595
488 4PLT OXM 5.13595
489 2Q46 NAP 5.13834
490 1P77 ATR 5.14706
491 6F9Q NAD 5.14706
492 2AUY NAG MAN MMA 5.15873
493 2AR6 NAG MAN MAN MAN NAG 5.15873
494 4D3F NAP 5.16129
495 4MO2 FAD 5.16304
496 4MO2 FDA 5.16304
497 1UXG FUM 5.17799
498 1UXG NAD 5.17799
499 5EOW FAD 5.18518
500 1NE7 AGP 5.19031
501 3VYW SAM 5.19481
502 5GZ6 NDP 5.21472
503 5GZ6 7C3 5.21472
504 2GAG NAD 5.2381
505 2GAG FOA 5.2381
506 2GAG FAD 5.2381
507 3NYC IAR 5.24934
508 3NYC FAD 5.24934
509 4U8P UDP 5.26316
510 4U8P FDA 5.26316
511 4X9M FAD 5.26316
512 1VM6 NAD 5.26316
513 2EJU SAH 5.29101
514 4R5M NAP 5.31915
515 1GZ6 NAI 5.32915
516 1JNR FAD 5.33333
517 5BUK FAD 5.33333
518 3P2E SAH 5.33333
519 4GLL NAD 5.34125
520 4CT7 TRP 5.34979
521 2FR1 NDP 5.34979
522 1ZK7 FAD 5.35332
523 3TLJ SAH 5.36193
524 1DL5 SAH 5.36278
525 1E3W NAD 5.36398
526 1WDK NAD 5.38462
527 1E6W NAD 5.38462
528 2AHR NAP 5.40541
529 4TM3 FAD 5.41761
530 9LDT NAD 5.42169
531 9LDB NAD 5.42169
532 1E6E FAD 5.43478
533 1E1M FAD 5.43478
534 1E1M NAP 5.43478
535 2YG3 FAD 5.51876
536 5GSN MMZ 5.51876
537 5GSN FAD 5.51876
538 5GSN NAP 5.51876
539 4YAG NAI 5.53633
540 4RDH AMP 5.55556
541 4RDI ATP 5.55556
542 1PNO NAP 5.55556
543 5Z21 NAI 5.58659
544 3WMX NAD 5.58659
545 2Z3Y F2N 5.58912
546 3CBG SAH 5.60345
547 2GDZ NAD 5.61798
548 5VEG FMN 5.61798
549 5N53 8NB 5.64103
550 5XNC MTA 5.66038
551 5N6C NAD 5.66667
552 5A7V BMA 5.6701
553 5A7V MAN 5.6701
554 5THY SAH 5.67901
555 1FP2 SAH 5.68182
556 1YKF NAP 5.68182
557 6H3O FAD 5.68356
558 1VQW FAD 5.68928
559 1LDN NAD 5.6962
560 2AG8 NAP 5.70342
561 1LSS NAD 5.71429
562 1OJJ BGC GAL 5.72139
563 5DXA SFG 5.73066
564 5DX0 SFG 5.73066
565 5ZMY TAR 5.73248
566 2CDC NAP 5.7377
567 2CDC XYP 5.7377
568 2CDC XYS 5.7377
569 1U7T NAD 5.74713
570 4E5N NAD 5.75758
571 4RPL FAD 5.76441
572 4RPL 3UC 5.76441
573 5ZI9 FLC 5.76923
574 3IHG FAD 5.79439
575 5E1M SAH 5.80913
576 2GVC FAD 5.81656
577 2GV8 NDP 5.81656
578 2GV8 FAD 5.81656
579 3FPZ AHZ 5.82822
580 1G55 SAH 5.8309
581 1KYQ NAD 5.83942
582 5EJ2 NAD 5.84416
583 3MAG SAH 5.86319
584 4JNA FAD 5.88235
585 1CDO NAD 5.88235
586 5HSA FAS 5.88235
587 6F7L FAD 5.88235
588 1NBU PH2 5.88235
589 3FUU ADN 5.90406
590 3H2B SAH 5.91133
591 5H81 NAP 5.9126
592 3IHB GLU 5.92105
593 1S7G NAD 5.92885
594 2RGO FAD 5.93081
595 6AA8 NAD 5.96026
596 3SSO SAH 5.96659
597 1BZL FAD 5.96708
598 1BZL GCG 5.96708
599 3KLJ FAD 5.97403
600 3OA2 NAD 5.97484
601 5ZBC FAD 5.9867
602 3KB6 NAD 5.98802
603 2DBZ NAP 5.98802
604 4KOA NDP 6.00601
605 5CK5 GDP 6.01266
606 1HDG NAD 6.0241
607 3I53 SAH 6.0241
608 1KYZ SAH 6.0274
609 1Z6Z NAP 6.02837
610 2PV7 NAD 6.04027
611 3SQP FAD 6.04878
612 3WGT QSC 6.05187
613 3WGT FAD 6.05187
614 3MCT SAH 6.06061
615 4NEC SAH 6.06061
616 1B8U NAD 6.07903
617 5LJI FMN 6.08108
618 4ZRN NAD 6.08974
619 1SOW NAD 6.09756
620 5EZ7 FAD 6.12245
621 5BRT FAD 6.14334
622 5BRT CH9 6.14334
623 4KIB SAH 6.16247
624 1D1T NAD 6.16622
625 1RJW ETF 6.19469
626 4ZCC NAI 6.25
627 4ZCC FAD 6.25
628 2YX1 SFG 6.25
629 2I3G NAP 6.25
630 3GMB FAD 6.26506
631 1I8T FAD 6.26703
632 6HKE LMR 6.28931
633 1W6U NAP 6.29139
634 1W8D NAP 6.29139
635 1W73 NAP 6.29139
636 3BAZ NAP 6.30631
637 3HVJ 705 6.33484
638 5EVY FAD 6.39269
639 1NVM NAD 6.41026
640 5LD5 NAD 6.42458
641 1O5I NAD 6.4257
642 6DWI HD4 6.43777
643 2CUL FAD 6.46552
644 5KVA SAM 6.47482
645 4TQG NDP 6.50155
646 5WP4 SAH 6.51731
647 1F06 NDP 6.5625
648 4NTC FAD 6.56716
649 5NMX FAD 6.58824
650 5NMX NAP 6.58824
651 1S7N COA 6.59341
652 3JQ8 NAP 6.59722
653 3BMN NAP 6.59722
654 5K6A NAP 6.59722
655 3JQA NAP 6.59722
656 4CM9 NAP 6.59722
657 5JDI NAP 6.59722
658 3BMQ NAP 6.59722
659 5JCJ NAP 6.59722
660 4CLO NAP 6.59722
661 3JQF NAP 6.59722
662 3BMO NAP 6.59722
663 4CM8 NAP 6.59722
664 4CMI NAP 6.59722
665 4CM4 NAP 6.59722
666 3JQG NAP 6.59722
667 4CLR NAP 6.59722
668 5JDC NAP 6.59722
669 3JQ9 NAP 6.59722
670 4CME NAP 6.59722
671 3JQ7 NAP 6.59722
672 3JQB NAP 6.59722
673 2B9W FAD 6.60377
674 6BII NAP 6.60661
675 4DSG UDP 6.61157
676 4DSG FAD 6.61157
677 2VHJ ADP 6.64653
678 4YNU LGC 6.65499
679 4YNU FAD 6.65499
680 2WPF FAD 6.66667
681 1ZQ9 SAM 6.66667
682 2WPF WPF 6.66667
683 5Z20 NAI 6.66667
684 5YEC ATP 6.72269
685 5ZZ6 ADP 6.73077
686 5ZZ6 NAD 6.73077
687 1FEC FAD 6.73469
688 4RSL FAD 6.74157
689 4NTO 1PW 6.76329
690 3H5N ATP 6.79887
691 1RM4 NDP 6.82493
692 2AOT SAH 6.84932
693 5G3U ITW 6.85579
694 5G3U FDA 6.85579
695 5HXI FAD 6.86016
696 5HXI 5HN 6.86016
697 4XUC 43G 6.88073
698 4XUC SAM 6.88073
699 5JE0 SAH 6.88259
700 5JE0 AZ8 6.88259
701 4BV6 FAD 6.89655
702 5N2I NAP 6.89655
703 3ZYR NAG NAG BMA MAN MAN NAG NAG 6.89655
704 2Q1W NAD 6.90691
705 2AG5 NAD 6.91057
706 3OFK SAH 6.94444
707 5ZI2 ADP 6.95652
708 5ZI2 NAD 6.95652
709 1QAN SAH 6.96721
710 6DNT NAD 6.97674
711 1ZGA SAH 7.0028
712 3QJ4 FAD 7.01754
713 3AD8 NAD 7.07071
714 3AD8 FAD 7.07071
715 3AD8 PYC 7.07071
716 4FN4 NAD 7.08661
717 2WD7 NAP 7.08955
718 1OMO NAD 7.14286
719 5X62 SAH 7.14286
720 4MDH NAD 7.18563
721 5MDH NAD 7.20721
722 3G89 SAM 7.22892
723 5MLR NAP 7.29927
724 5MLR GRQ 7.29927
725 3QV1 NAD 7.31707
726 3DXY SAM 7.33945
727 2CVQ NDP 7.33945
728 3OID NDP 7.36434
729 4R6W SAH 7.36434
730 1U1I NAD 7.39796
731 4ITU NAI 7.43494
732 1PS9 FAD 7.45156
733 1PS9 NAP 7.45156
734 1LTH NAD 7.52351
735 3H8V ATP 7.53425
736 2Y6Q FAD 7.53769
737 2Y6Q I7T 7.53769
738 4JDR FAD 7.59494
739 5TC4 NAD 7.59494
740 4KRI SAH 7.62125
741 2HJR APR 7.62195
742 5A96 GTP 7.63052
743 1LVL NAD 7.64192
744 1LVL FAD 7.64192
745 5O4J PJL 7.66423
746 5O4J SAH 7.66423
747 5O4J 9KH 7.66423
748 2VAR KDF 7.66773
749 2Q7V FAD 7.69231
750 5THQ NDP 7.72059
751 1V8B NAD 7.72443
752 4MOP 2H5 7.74092
753 2ZIF SAM 7.74411
754 4CQM NAP 7.78689
755 5BVA FAD 7.82396
756 5NM7 GLY 7.89474
757 1NT4 G1P 7.92839
758 2YY8 MTA 7.9602
759 1N2X SAM 7.97342
760 3Q87 SAM 8
761 3C3Y SAH 8.01688
762 3Q3C NAD 8.02676
763 2CH5 NDG 8.06916
764 2CH5 NAG 8.06916
765 2PT9 S4M