Receptor
PDB id Resolution Class Description Source Keywords
1H2C 1.6 Å NON-ENZYME: TOXIN_VIRAL EBOLA VIRUS MATRIX PROTEIN VP40 N-TERMINAL DOMAIN IN COMPLEX WITH RNA (HIGH-RESOLUTION VP40[55-194] VARIANT). EBOLA VIRUS VIRUS/VIRAL PROTEIN FILOVIRUS EBOLA VIRUS MATRIX PROTEIN VP40 ASSEMBLY BUDDING
Ref.: THE MATRIX PROTEIN VP40 FROM EBOLA VIRUS OCTAMERIZES INTO PORE-LIKE STRUCTURES WITH SPECIFIC RNA BINDING PROPERTIES STRUCTURE V. 11 423 2003
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
U G A R:1;
Valid;
none;
submit data
916.604 n/a [P+](...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1H2C 1.6 Å NON-ENZYME: TOXIN_VIRAL EBOLA VIRUS MATRIX PROTEIN VP40 N-TERMINAL DOMAIN IN COMPLEX WITH RNA (HIGH-RESOLUTION VP40[55-194] VARIANT). EBOLA VIRUS VIRUS/VIRAL PROTEIN FILOVIRUS EBOLA VIRUS MATRIX PROTEIN VP40 ASSEMBLY BUDDING
Ref.: THE MATRIX PROTEIN VP40 FROM EBOLA VIRUS OCTAMERIZES INTO PORE-LIKE STRUCTURES WITH SPECIFIC RNA BINDING PROPERTIES STRUCTURE V. 11 423 2003
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 60 families.
1 1H2C - U G A n/a n/a
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 42 families.
1 1H2C - U G A n/a n/a
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 34 families.
1 1H2C - U G A n/a n/a
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: U G A; Similar ligands found: 161
No: Ligand ECFP6 Tc MDL keys Tc
1 U G A 1 1
2 A G U 0.854962 1
3 G A A A 0.792 0.962025
4 U A G G 0.757812 0.949367
5 U A A U 0.695652 0.925
6 A U 0.671756 0.936709
7 A U C C 0.659722 0.962025
8 APC G U 0.656934 0.901235
9 G G 0.622047 0.949367
10 G C 0.604317 0.987342
11 G G G RPC 0.592857 0.962025
12 G G G C 0.590278 0.975
13 G3A 0.586466 0.91358
14 A G C C 0.586207 0.974684
15 G5P 0.58209 0.91358
16 G C C C 0.581081 0.9625
17 U2G 0.571429 0.950617
18 UPA 0.568345 0.901235
19 APU 0.564286 0.9125
20 A A 0.557252 0.8625
21 4TC 0.557143 0.86747
22 U A C C 0.554795 0.949367
23 UP5 0.553957 0.888889
24 ATP A A A 0.552239 0.873418
25 G U34 0.545455 0.975
26 OMC OMU OMG OMG U 0.53125 0.951219
27 G G U 0.521429 0.925
28 ALF 5GP 0.503817 0.858824
29 139 0.503401 0.869048
30 UCG 0.503226 0.925926
31 CG2 0.5 0.950617
32 GDP MG 0.496183 0.890244
33 GDP BEF 0.492424 0.869048
34 5GP 0.488189 0.9
35 G 0.488189 0.9
36 GDP ALF 0.481752 0.858824
37 GDP AF3 0.481752 0.858824
38 BEF GDP 0.481481 0.858824
39 GTP MG 0.481481 0.890244
40 PUA 0.477419 0.857143
41 G3D 0.474074 0.876543
42 A A A 0.471014 0.829268
43 GAP 0.469697 0.864198
44 GDP 0.469697 0.888889
45 G4P 0.467153 0.876543
46 GPG 0.464286 0.925926
47 GKE 0.461538 0.902439
48 GDD 0.461538 0.902439
49 GDC 0.461538 0.902439
50 GP2 0.458647 0.857143
51 GNH 0.455224 0.878049
52 0O2 0.453901 0.876543
53 ADP MG 0.453846 0.829268
54 DG DA DC DG 0.453488 0.939759
55 GSP 0.452555 0.847059
56 G2P 0.452555 0.857143
57 GP3 0.451128 0.91358
58 DA DC DG DA 0.450867 0.939759
59 ADP BEF 0.450382 0.809524
60 BEF ADP 0.450382 0.809524
61 G1R G1R 0.45 0.914634
62 ADP BMA 0.45 0.864198
63 DC DG DA DC 0.449704 0.915663
64 3GP 0.449612 0.8875
65 GTP 0.448529 0.888889
66 ANP MG 0.448529 0.8
67 GAV 0.446043 0.857143
68 GCP G 0.446043 0.901235
69 GCP 0.445255 0.86747
70 U U 0.445255 0.8125
71 U U U U 0.444444 0.8
72 ADP PO3 0.443609 0.860759
73 GDP 7MG 0.442177 0.925926
74 ADP ALF 0.441176 0.8
75 ALF ADP 0.441176 0.8
76 AMP MG 0.440945 0.817073
77 ATP MG 0.440298 0.829268
78 ADP VO4 0.437956 0.829268
79 GMV 0.437956 0.86747
80 VO4 ADP 0.437956 0.829268
81 G2R 0.43662 0.857143
82 AMP 0.436508 0.8375
83 A 0.436508 0.8375
84 4TA 0.435897 0.848837
85 3PD UM3 0.435065 0.926829
86 G1R 0.434783 0.878049
87 SFB 0.434211 0.736842
88 DT DA DC DG 0.431694 0.895349
89 GNP 0.431655 0.86747
90 JBT 0.430693 0.757576
91 GPC 0.43038 0.916667
92 GTA 0.42953 0.903614
93 JB2 0.42953 0.879518
94 DC DG DT DA 0.429348 0.895349
95 4BW 0.428571 0.8875
96 1YD 0.428571 0.8875
97 ADP 0.427481 0.839506
98 6CK 0.425676 0.858824
99 GMP 0.424 0.825
100 DAL AMP 0.421429 0.851852
101 PAX 0.420732 0.848837
102 Z5A 0.420732 0.840909
103 MYR AMP 0.42069 0.775281
104 DC DG 0.420382 0.927711
105 UTP U U U 0.42029 0.78481
106 GKD 0.42 0.902439
107 A3P 0.419847 0.8375
108 GFB 0.418919 0.879518
109 GDR 0.418919 0.879518
110 ADQ 0.415493 0.841463
111 A2D 0.415385 0.839506
112 ABM 0.415385 0.795181
113 YGP 0.414966 0.892857
114 PRX 0.414815 0.776471
115 AN2 0.413534 0.829268
116 JB3 0.412903 0.869048
117 Y9Z 0.412162 0.829545
118 PGD O 0.412121 0.844444
119 DU DU DU DU BRU DG DU 0.411765 0.875
120 PAP 0.411765 0.82716
121 AGS 0.411765 0.8
122 SAP 0.411765 0.8
123 A22 0.411348 0.851852
124 SRA 0.410853 0.797619
125 CA0 0.410448 0.819277
126 DA DU DG DA 0.410256 0.870588
127 I2C FE2 CMO CMO 0.409938 0.844444
128 4UV 0.409396 0.843373
129 AMP DBH 0.409396 0.841463
130 AP2 0.409091 0.809524
131 BA3 0.409091 0.839506
132 A12 0.409091 0.809524
133 25A 0.408451 0.8625
134 GDX 0.407895 0.890244
135 ZGP 0.407643 0.840909
136 ATP 0.407407 0.839506
137 B4P 0.406015 0.839506
138 AP5 0.406015 0.839506
139 ACQ 0.405797 0.819277
140 ANP 0.405797 0.819277
141 TAT 0.405797 0.809524
142 4AD 0.405594 0.821429
143 5FA 0.404412 0.839506
144 AQP 0.404412 0.839506
145 APC 0.404412 0.809524
146 AR6 AR6 0.403974 0.8625
147 4UU 0.403974 0.843373
148 A4P 0.403846 0.883721
149 CAG 0.403727 0.852273
150 TYR AMP 0.402685 0.853659
151 4UW 0.402597 0.813953
152 2MD 0.402516 0.862069
153 CSV 0.401361 0.819277
154 CSQ 0.401361 0.819277
155 FEG 0.401274 0.850575
156 NAJ PZO 0.401235 0.86747
157 AU1 0.4 0.819277
158 M33 0.4 0.807229
159 ADX 0.4 0.744444
160 GTG 0.4 0.903614
161 ATF 0.4 0.809524
Similar Binding Sites (Proteins are less than 50% similar to leader)
Feedback