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Receptor
PDB id Resolution Class Description Source Keywords
1H74 1.9 Å EC: 2.7.1.39 CRYSTAL STRUCTURE OF HOMOSERINE KINASE COMPLEXED WITH ILE METHANOCOCCUS JANNASCHII TRANSFERASE KINASE
Ref.: STRUCTURAL BASIS FOR THE CATALYSIS AND SUBSTRATE SPECIFICITY OF HOMOSERINE KINASE BIOCHEMISTRY V. 40 10810 2001
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ADP A:400;
C:400;
Valid;
Valid;
none;
none;
submit data
427.201 C10 H15 N5 O10 P2 c1nc(...
ILE A:500;
B:500;
C:500;
D:500;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
submit data
131.173 C6 H13 N O2 CC[C@...
MG B:600;
Part of Protein;
none;
submit data
24.305 Mg [Mg+2...
SAP B:400;
D:400;
Valid;
Valid;
none;
none;
submit data
523.247 C10 H16 N5 O12 P3 S c1nc(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1H74 1.9 Å EC: 2.7.1.39 CRYSTAL STRUCTURE OF HOMOSERINE KINASE COMPLEXED WITH ILE METHANOCOCCUS JANNASCHII TRANSFERASE KINASE
Ref.: STRUCTURAL BASIS FOR THE CATALYSIS AND SUBSTRATE SPECIFICITY OF HOMOSERINE KINASE BIOCHEMISTRY V. 40 10810 2001
Members (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 1H72 - HSE C4 H9 N O3 C(CO)[C@@H....
2 1FWK - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
3 1H73 - THR C4 H9 N O3 C[C@H]([C@....
4 1H74 - ILE C6 H13 N O2 CC[C@H](C)....
70% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 1H72 - HSE C4 H9 N O3 C(CO)[C@@H....
2 1FWK - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
3 1H73 - THR C4 H9 N O3 C[C@H]([C@....
4 1H74 - ILE C6 H13 N O2 CC[C@H](C)....
50% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 1H72 - HSE C4 H9 N O3 C(CO)[C@@H....
2 1FWK - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
3 1H73 - THR C4 H9 N O3 C[C@H]([C@....
4 1H74 - ILE C6 H13 N O2 CC[C@H](C)....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ADP; Similar ligands found: 452
No: Ligand ECFP6 Tc MDL keys Tc
1 ADP 1 1
2 HEJ 0.9 1
3 ATP 0.9 1
4 A2D 0.895522 0.971831
5 5FA 0.887324 1
6 AQP 0.887324 1
7 AP5 0.884058 0.971831
8 B4P 0.884058 0.971831
9 BA3 0.869565 0.971831
10 AN2 0.84507 0.985915
11 AT4 0.84507 0.958904
12 M33 0.833333 0.958333
13 ACQ 0.826667 0.972222
14 A 0.823529 0.971429
15 AMP 0.823529 0.971429
16 ACP 0.821918 0.972222
17 6YZ 0.818182 0.972222
18 APR 0.810811 0.971831
19 AR6 0.810811 0.971831
20 ANP 0.802632 0.972222
21 SAP 0.8 0.945946
22 AGS 0.8 0.945946
23 AD9 0.8 0.972222
24 ADX 0.783784 0.873418
25 CA0 0.783784 0.945205
26 TAT 0.779221 0.958904
27 T99 0.779221 0.958904
28 50T 0.773333 0.958333
29 ABM 0.763889 0.917808
30 APC 0.763158 0.958904
31 PRX 0.763158 0.893333
32 ATF 0.759494 0.958904
33 A22 0.753086 0.985915
34 AP2 0.743243 0.958904
35 A12 0.743243 0.958904
36 SRA 0.736111 0.918919
37 ADQ 0.73494 0.945205
38 25L 0.732558 0.985915
39 5AL 0.725 0.931507
40 2A5 0.717949 0.918919
41 A1R 0.714286 0.907895
42 AU1 0.714286 0.972222
43 A3R 0.714286 0.907895
44 ATR 0.708861 0.971429
45 ADP PO3 0.708861 0.943662
46 PAP 0.708861 0.985714
47 SRP 0.707317 0.906667
48 7D3 0.706667 0.905405
49 25A 0.702381 0.971831
50 9X8 0.697674 0.92
51 OAD 0.697674 0.945205
52 RBY 0.6875 0.932432
53 ADV 0.6875 0.932432
54 00A 0.686047 0.883117
55 OOB 0.682353 0.931507
56 5SV 0.682353 0.848101
57 8QN 0.682353 0.931507
58 3OD 0.681818 0.945205
59 BIS 0.681818 0.933333
60 ALF ADP 0.674699 0.87013
61 ADP ALF 0.674699 0.87013
62 AMO 0.674419 0.932432
63 4AD 0.674419 0.92
64 PAJ 0.674419 0.884615
65 GAP 0.670732 0.893333
66 MAP 0.670588 0.945946
67 AHX 0.666667 0.896104
68 VO4 ADP 0.666667 0.931507
69 DLL 0.666667 0.931507
70 ADP VO4 0.666667 0.931507
71 PTJ 0.662921 0.896104
72 3UK 0.659091 0.918919
73 SON 0.658228 0.932432
74 LMS 0.653333 0.82716
75 LAD 0.651685 0.860759
76 WAQ 0.651685 0.883117
77 B5V 0.651685 0.906667
78 PR8 0.651685 0.85
79 ITT 0.65 0.943662
80 7D4 0.65 0.905405
81 G5P 0.648936 0.921053
82 XYA 0.647059 0.84507
83 ADN 0.647059 0.84507
84 RAB 0.647059 0.84507
85 1ZZ 0.644444 0.839506
86 ME8 0.644444 0.839506
87 FYA 0.644444 0.905405
88 NB8 0.644444 0.896104
89 TXA 0.644444 0.932432
90 6AD 0.642857 0.909091
91 ADP BMA 0.640449 0.918919
92 G3A 0.638298 0.921053
93 DAL AMP 0.632184 0.905405
94 AFH 0.631579 0.884615
95 9SN 0.630435 0.871795
96 9ZA 0.625 0.907895
97 DQV 0.625 0.958333
98 9ZD 0.625 0.907895
99 GTA 0.625 0.886076
100 YAP 0.623656 0.894737
101 B5M 0.623656 0.894737
102 FA5 0.623656 0.906667
103 B5Y 0.623656 0.894737
104 UP5 0.622449 0.92
105 HFD 0.619048 0.945946
106 XAH 0.617021 0.839506
107 AV2 0.616279 0.917808
108 AOC 0.615385 0.821918
109 48N 0.612245 0.896104
110 4UV 0.610526 0.894737
111 6V0 0.606061 0.896104
112 NAI 0.606061 0.907895
113 DND 0.606061 0.932432
114 NAX 0.606061 0.873418
115 NXX 0.606061 0.932432
116 TXD 0.606061 0.907895
117 5N5 0.605634 0.819444
118 5AS 0.604938 0.77907
119 A4P 0.60396 0.843373
120 DAT 0.60241 0.905405
121 A2R 0.602273 0.985915
122 TXE 0.6 0.907895
123 OMR 0.6 0.851852
124 4UU 0.597938 0.894737
125 GA7 0.597938 0.906667
126 A A 0.597826 0.944444
127 A4D 0.597222 0.819444
128 5CD 0.597222 0.805556
129 AP0 0.594059 0.896104
130 4TC 0.594059 0.896104
131 A3P 0.592593 0.971429
132 T5A 0.592233 0.841463
133 139 0.592233 0.873418
134 7D5 0.592105 0.878378
135 ATP A A A 0.589474 0.930556
136 LAQ 0.585859 0.839506
137 MYR AMP 0.585106 0.817073
138 F2R 0.580952 0.864198
139 YLP 0.58 0.819277
140 UPA 0.578431 0.907895
141 7DD 0.578313 0.985714
142 3AM 0.576923 0.929577
143 ADJ 0.576923 0.851852
144 COD 0.575472 0.811765
145 NAD 0.575472 0.931507
146 3AT 0.574713 0.971831
147 JB6 0.574468 0.883117
148 4UW 0.574257 0.860759
149 EP4 0.573333 0.753247
150 A2P 0.573171 0.957143
151 CNA 0.571429 0.932432
152 TYM 0.568627 0.906667
153 PPS 0.568182 0.873418
154 DTA 0.565789 0.786667
155 M2T 0.565789 0.734177
156 AR6 AR6 0.565657 0.917808
157 A3D 0.564815 0.918919
158 80F 0.564815 0.841463
159 3DH 0.564103 0.773333
160 G5A 0.563218 0.77907
161 YLB 0.563107 0.819277
162 YLC 0.563107 0.839506
163 AMP DBH 0.561224 0.893333
164 TYR AMP 0.561224 0.87013
165 MTA 0.558442 0.773333
166 DTP 0.556818 0.905405
167 AHZ 0.554455 0.817073
168 NA7 0.553191 0.958904
169 IOT 0.552381 0.831325
170 ZAS 0.55 0.766234
171 7MD 0.55 0.8625
172 ARG AMP 0.55 0.829268
173 IMO 0.548781 0.929577
174 YLA 0.54717 0.819277
175 NAE 0.544643 0.894737
176 TAD 0.544554 0.884615
177 A5A 0.544444 0.807229
178 2AM 0.544304 0.943662
179 TSB 0.543478 0.819277
180 6RE 0.54321 0.759494
181 AYB 0.542056 0.809524
182 NAQ 0.539823 0.871795
183 V3L 0.539326 0.971831
184 SSA 0.538462 0.8
185 AF3 ADP 3PG 0.538462 0.8375
186 ZID 0.535088 0.918919
187 LPA AMP 0.533981 0.817073
188 52H 0.532609 0.77907
189 VMS 0.532609 0.788235
190 54H 0.532609 0.788235
191 BTX 0.53211 0.841463
192 A3N 0.53012 0.786667
193 J7C 0.53012 0.769231
194 5X8 0.528736 0.763158
195 BT5 0.527273 0.831325
196 8X1 0.526882 0.752809
197 5CA 0.526882 0.8
198 53H 0.526882 0.77907
199 ARU 0.526316 0.860759
200 EAD 0.525862 0.873418
201 RGT 0.525253 0.958904
202 OVE 0.52439 0.905405
203 S4M 0.52381 0.666667
204 7DT 0.522727 0.985714
205 GDP 0.522222 0.92
206 DDS 0.522222 0.878378
207 AVV 0.521277 0.896104
208 NDE 0.521008 0.932432
209 7MC 0.518868 0.841463
210 DSH 0.518072 0.725
211 MAO 0.517647 0.759036
212 NSS 0.515789 0.8
213 DSZ 0.515789 0.8
214 LSS 0.515789 0.761364
215 P5A 0.515464 0.744444
216 DZD 0.513514 0.884615
217 NVA LMS 0.510417 0.752809
218 9K8 0.510204 0.714286
219 12D 0.509615 0.785714
220 M24 0.508772 0.85
221 YLY 0.508772 0.809524
222 P1H 0.508333 0.851852
223 5AD 0.506849 0.746479
224 GJV 0.505882 0.75
225 LEU LMS 0.505155 0.752809
226 AMP NAD 0.504505 0.905405
227 4TA 0.504505 0.807229
228 G A A A 0.504505 0.871795
229 NAJ PZO 0.504425 0.848101
230 GSU 0.5 0.77907
231 128 0.5 0.776471
232 KAA 0.5 0.752809
233 71V 0.5 0.907895
234 A3G 0.5 0.8
235 NDC 0.5 0.871795
236 7D7 0.5 0.743243
237 N0B 0.495726 0.819277
238 NJP 0.495495 0.945946
239 ODP 0.495495 0.909091
240 2SA 0.494624 0.932432
241 6C6 0.494505 0.881579
242 SFG 0.494382 0.75
243 0WD 0.491071 0.921053
244 YSA 0.490196 0.77907
245 PO4 PO4 A A A A PO4 0.489796 0.902778
246 SAM 0.48913 0.690476
247 6IA 0.48913 0.8375
248 A7D 0.488636 0.776316
249 6FA 0.488 0.841463
250 FB0 0.487805 0.804598
251 NAJ PYZ 0.487179 0.807229
252 A5D 0.483516 0.786667
253 IDP 0.483516 0.918919
254 SA8 0.483516 0.707317
255 PGS 0.483146 0.883117
256 MHZ 0.483146 0.697674
257 DA 0.482353 0.878378
258 D5M 0.482353 0.878378
259 NEC 0.482353 0.746667
260 NIA 0.481928 0.822785
261 Y3J 0.480519 0.726027
262 8PZ 0.480392 0.8
263 FAD 0.480315 0.851852
264 FAS 0.480315 0.851852
265 FDA 0.48 0.833333
266 N6P 0.479592 0.915493
267 GGZ 0.479167 0.825
268 U A 0.478261 0.907895
269 SAH 0.478261 0.74359
270 SAI 0.478261 0.734177
271 A G 0.477876 0.883117
272 NPW 0.477477 0.886076
273 NDP 0.477477 0.921053
274 AAM 0.476744 0.971429
275 C2R 0.47561 0.90411
276 AMZ 0.47561 0.916667
277 A A A 0.474747 0.905405
278 GTP 0.473684 0.92
279 U A G G 0.473684 0.883117
280 SMM 0.473684 0.686047
281 NZQ 0.473214 0.909091
282 TXP 0.473214 0.921053
283 A3S 0.47191 0.810811
284 SFD 0.46875 0.734043
285 AIR 0.468354 0.901408
286 AAT 0.468085 0.707317
287 EEM 0.468085 0.690476
288 J7V 0.466667 0.833333
289 Z5A 0.466667 0.77907
290 7C5 0.466667 0.818182
291 62F 0.465649 0.8625
292 HDV 0.463158 0.893333
293 FAY 0.462121 0.8625
294 A3T 0.461538 0.821918
295 ETB 0.461538 0.833333
296 DCA 0.461538 0.823529
297 A6D 0.46 0.722892
298 A U 0.459459 0.87013
299 GEK 0.459184 0.7375
300 6K6 0.459184 0.930556
301 RFL 0.458647 0.821429
302 NAP 0.458333 0.945205
303 S7M 0.458333 0.690476
304 4YB 0.457944 0.761364
305 WSA 0.454545 0.788235
306 TAP 0.454545 0.907895
307 FNK 0.454545 0.804598
308 COA 0.453782 0.823529
309 0T1 0.453782 0.823529
310 101 0.453488 0.878378
311 XNP 0.452174 0.873418
312 NA0 0.45082 0.932432
313 7RP 0.448276 0.928571
314 GP3 0.446809 0.921053
315 TM1 0.446602 0.77381
316 APU 0.446429 0.894737
317 PUA 0.445378 0.884615
318 V1N 0.443396 0.917808
319 7RA 0.443182 0.957747
320 COS 0.442623 0.804598
321 AMX 0.442623 0.833333
322 30N 0.442623 0.752688
323 CAO 0.442623 0.795455
324 QQY 0.44186 0.815789
325 ACK 0.44186 0.861111
326 649 0.441441 0.744444
327 0UM 0.44 0.698795
328 NHD 0.439655 0.905405
329 CMX 0.439024 0.823529
330 SCO 0.439024 0.823529
331 GCP 0.438776 0.896104
332 8BR 0.438202 0.906667
333 GNH 0.4375 0.907895
334 8Q2 0.4375 0.772727
335 3AD 0.4375 0.805556
336 NVA 2AD 0.43617 0.759494
337 62X 0.435644 0.666667
338 FCX 0.435484 0.795455
339 ACO 0.435484 0.795455
340 FAM 0.435484 0.804598
341 9JJ 0.434783 0.8625
342 GNP 0.434343 0.896104
343 9GM 0.434343 0.896104
344 NMX 0.433071 0.76087
345 MGP 0.43299 0.884615
346 26A 0.432099 0.763158
347 HAX 0.432 0.804598
348 K15 0.431373 0.682353
349 DG1 0.430894 0.921053
350 1DG 0.430894 0.921053
351 QQX 0.430233 0.805195
352 2VA 0.430108 0.8
353 S8M 0.43 0.759494
354 2MC 0.429688 0.769231
355 6G0 0.428571 0.884615
356 P5F 0.428571 0.823529
357 FYN 0.428571 0.823529
358 3KK 0.428571 0.804598
359 A C A C 0.428571 0.848101
360 7L1 0.427419 0.795455
361 FAI 0.426966 0.916667
362 RMB 0.426966 0.873239
363 AS 0.426966 0.833333
364 1RB 0.425287 0.885714
365 CA6 0.425197 0.729167
366 SOP 0.425197 0.804598
367 OXK 0.425197 0.804598
368 MCD 0.425197 0.804598
369 COK 0.425197 0.804598
370 G1R 0.424242 0.907895
371 SXZ 0.423077 0.710843
372 CC5 0.423077 0.816901
373 F2N 0.422535 0.813953
374 EO7 0.422222 0.788235
375 ANZ 0.422018 0.8
376 1VU 0.421875 0.795455
377 CMC 0.421875 0.804598
378 CO6 0.421875 0.804598
379 ZDA 0.421053 0.864865
380 GKE 0.420561 0.884615
381 GDC 0.420561 0.884615
382 GDD 0.420561 0.884615
383 NFD 0.420168 0.883117
384 GSP 0.42 0.873418
385 D3Y 0.42 0.789474
386 MC4 0.419847 0.76087
387 3D1 0.419753 0.773333
388 3L1 0.419753 0.773333
389 FA9 0.41958 0.864198
390 5GP 0.419355 0.906667
391 G 0.419355 0.906667
392 KB1 0.419048 0.698795
393 CAJ 0.418605 0.804598
394 SCD 0.418605 0.823529
395 CMP 0.417582 0.901408
396 2BA 0.417582 0.915493
397 SO8 0.416667 0.789474
398 VRT 0.416667 0.769231
399 N01 0.416667 0.905405
400 IVC 0.415385 0.813953
401 1HE 0.415385 0.786517
402 A1S 0.415385 0.804598
403 BCO 0.415385 0.804598
404 3HC 0.415385 0.813953
405 MLC 0.415385 0.804598
406 NMN AMP PO4 0.415254 0.87013
407 2FA 0.414634 0.813333
408 MGO 0.414141 0.860759
409 3NZ 0.413462 0.782051
410 COO 0.412214 0.804598
411 MCA 0.412214 0.795455
412 YE1 0.412214 0.813953
413 CAA 0.412214 0.813953
414 GAV 0.411765 0.884615
415 PRT 0.411215 0.931507
416 JLN 0.411111 0.890411
417 P2P 0.411111 0.902778
418 ZZB 0.410256 0.77381
419 SP1 0.409091 0.842105
420 RP1 0.409091 0.842105
421 2CP 0.409091 0.795455
422 SCA 0.409091 0.804598
423 103 0.409091 0.837838
424 PAX 0.408 0.829268
425 FAD NBT 0.407143 0.75
426 COW 0.406015 0.795455
427 3CP 0.406015 0.804598
428 IRC 0.406015 0.813953
429 BYC 0.406015 0.804598
430 CA8 0.406015 0.729167
431 1GZ 0.406015 0.795455
432 COF 0.406015 0.786517
433 HGG 0.406015 0.804598
434 2KQ 0.406015 0.786517
435 G2P 0.405941 0.884615
436 SLU 0.404959 0.770115
437 U A C C 0.404959 0.858974
438 RBZ 0.404494 0.849315
439 1CZ 0.404412 0.795455
440 FAQ 0.402985 0.804598
441 BCA 0.402985 0.795455
442 4CA 0.402985 0.795455
443 MTP 0.402439 0.730769
444 8OD 0.402062 0.945205
445 CO7 0.401515 0.804598
446 GRA 0.4 0.804598
447 G2R 0.4 0.884615
448 ENQ 0.4 0.916667
449 CNV FAD 0.4 0.8
450 GMV 0.4 0.896104
451 HXC 0.4 0.786517
452 HF7 0.4 0.893333
Ligand no: 2; Ligand: ILE; Similar ligands found: 12
No: Ligand ECFP6 Tc MDL keys Tc
1 ILE 1 1
2 VAL 0.565217 0.727273
3 MD0 0.551724 0.655172
4 THR 0.541667 0.6
5 ALO 0.541667 0.6
6 VAH 0.538462 0.703704
7 DAL 0.5 0.714286
8 ALA 0.5 0.714286
9 DBB 0.5 0.782609
10 ABA 0.5 0.782609
11 NVA 0.428571 0.833333
12 LEU 0.428571 0.791667
Ligand no: 3; Ligand: SAP; Similar ligands found: 423
No: Ligand ECFP6 Tc MDL keys Tc
1 AGS 1 1
2 SAP 1 1
3 BA3 0.887324 0.92
4 B4P 0.875 0.92
5 AP5 0.875 0.92
6 A2D 0.859155 0.92
7 HEJ 0.84 0.945946
8 ATP 0.84 0.945946
9 AQP 0.828947 0.945946
10 5FA 0.828947 0.945946
11 AN2 0.813333 0.933333
12 ADP 0.8 0.945946
13 AT4 0.789474 0.986486
14 APR 0.782051 0.92
15 AR6 0.782051 0.92
16 M33 0.779221 0.907895
17 AD9 0.772152 0.921053
18 ACP 0.769231 0.921053
19 SRA 0.756757 0.972973
20 A22 0.75 0.933333
21 50T 0.746835 0.907895
22 AMP 0.743243 0.918919
23 A 0.743243 0.918919
24 ADX 0.734177 0.9
25 CA0 0.734177 0.896104
26 ADQ 0.732558 0.896104
27 ANP 0.731707 0.921053
28 ACQ 0.731707 0.921053
29 25L 0.730337 0.933333
30 6YZ 0.72619 0.921053
31 PRX 0.716049 0.848101
32 9X8 0.715909 0.947368
33 OAD 0.715909 0.896104
34 ATF 0.714286 0.909091
35 ABM 0.714286 0.87013
36 AP2 0.696203 0.909091
37 A12 0.696203 0.909091
38 A1R 0.693182 0.8625
39 A3R 0.693182 0.8625
40 TAT 0.690476 0.986486
41 T99 0.690476 0.986486
42 5AL 0.682353 0.883117
43 25A 0.681818 0.92
44 3OD 0.681319 0.896104
45 APC 0.674699 0.909091
46 AU1 0.670732 0.921053
47 SRP 0.666667 0.860759
48 G3A 0.65625 0.875
49 4AD 0.655556 0.873418
50 G5P 0.649485 0.875
51 AFH 0.649485 0.841463
52 00A 0.648352 0.839506
53 RBY 0.647059 0.884615
54 ADP PO3 0.647059 0.893333
55 ADV 0.647059 0.884615
56 BIS 0.645161 0.886076
57 5SV 0.644444 0.807229
58 8QN 0.644444 0.883117
59 OOB 0.644444 0.883117
60 GTA 0.642857 0.843373
61 PAJ 0.637363 0.841463
62 AMO 0.637363 0.884615
63 ITT 0.630952 0.893333
64 DLL 0.630435 0.883117
65 AHX 0.630435 0.851852
66 ADP VO4 0.629214 0.883117
67 VO4 ADP 0.629214 0.883117
68 NB8 0.62766 0.851852
69 UP5 0.623762 0.873418
70 3UK 0.623656 0.871795
71 SON 0.619048 0.884615
72 ALF ADP 0.617977 0.82716
73 ADP ALF 0.617977 0.82716
74 OMR 0.617647 0.811765
75 PR8 0.617021 0.809524
76 WAQ 0.617021 0.839506
77 B5V 0.617021 0.860759
78 LAD 0.617021 0.819277
79 DAL AMP 0.615385 0.858974
80 MAP 0.615385 0.897436
81 GAP 0.613636 0.848101
82 LMS 0.6125 0.853659
83 7D4 0.611765 0.858974
84 1ZZ 0.610526 0.8
85 FYA 0.610526 0.858974
86 ME8 0.610526 0.821429
87 TXA 0.610526 0.884615
88 PTJ 0.610526 0.851852
89 DQV 0.61 0.907895
90 ATR 0.609195 0.918919
91 PAP 0.609195 0.932432
92 NAI 0.607843 0.8625
93 NAX 0.607843 0.831325
94 6V0 0.607843 0.851852
95 ADP BMA 0.606383 0.871795
96 A4P 0.605769 0.804598
97 A2R 0.604396 0.933333
98 XYA 0.60274 0.8
99 RAB 0.60274 0.8
100 ADN 0.60274 0.8
101 48N 0.598039 0.851852
102 9SN 0.597938 0.829268
103 139 0.59434 0.831325
104 T5A 0.59434 0.802326
105 NXX 0.592233 0.884615
106 DND 0.592233 0.884615
107 TXD 0.592233 0.8625
108 B5M 0.591837 0.85
109 B5Y 0.591837 0.85
110 YAP 0.591837 0.85
111 FA5 0.591837 0.860759
112 9ZD 0.591398 0.8625
113 9ZA 0.591398 0.8625
114 TXE 0.586538 0.8625
115 XAH 0.585859 0.8
116 HFD 0.58427 0.897436
117 GA7 0.584158 0.860759
118 A A 0.583333 0.894737
119 AP0 0.580952 0.851852
120 4UV 0.58 0.85
121 2A5 0.579545 0.871795
122 AOC 0.578313 0.779221
123 COD 0.577982 0.795455
124 A3P 0.576471 0.918919
125 ATP A A A 0.575758 0.881579
126 CNA 0.574074 0.884615
127 LAQ 0.572816 0.865854
128 5AS 0.569767 0.804598
129 4UU 0.568627 0.85
130 YLP 0.567308 0.781609
131 4TC 0.566038 0.851852
132 UPA 0.566038 0.8625
133 YLB 0.566038 0.781609
134 5N5 0.565789 0.776316
135 ADJ 0.564815 0.811765
136 7D3 0.564706 0.858974
137 3AM 0.560976 0.88
138 5CD 0.558442 0.763158
139 A4D 0.558442 0.8
140 A2P 0.55814 0.905405
141 NA7 0.556701 0.909091
142 F2R 0.554545 0.823529
143 PPS 0.554348 0.9
144 G5A 0.549451 0.804598
145 GSP 0.547368 0.924051
146 4UW 0.54717 0.819277
147 JB6 0.545455 0.910256
148 3AT 0.543478 0.92
149 TYM 0.542056 0.860759
150 MYR AMP 0.54 0.77907
151 80F 0.539823 0.845238
152 AR6 AR6 0.538462 0.87013
153 EP4 0.5375 0.716049
154 YLC 0.537037 0.8
155 7D5 0.536585 0.833333
156 NAD 0.535714 0.883117
157 TYR AMP 0.533981 0.82716
158 DTA 0.530864 0.792208
159 M2T 0.530864 0.719512
160 3DH 0.53012 0.75641
161 2AM 0.53012 0.893333
162 AHZ 0.528302 0.821429
163 IOT 0.527273 0.793103
164 DTP 0.526882 0.858974
165 SSA 0.526316 0.825581
166 A3D 0.526316 0.871795
167 MTA 0.52439 0.75641
168 ARG AMP 0.52381 0.790698
169 YLA 0.522523 0.781609
170 BTX 0.522124 0.845238
171 6AD 0.521277 0.911392
172 AMP DBH 0.519231 0.848101
173 TAD 0.518868 0.8875
174 AYB 0.517857 0.772727
175 BT5 0.517544 0.835294
176 A5A 0.515789 0.833333
177 TSB 0.515464 0.845238
178 OVE 0.511628 0.933333
179 6RE 0.511628 0.722892
180 7DT 0.51087 0.932432
181 V3L 0.510638 0.92
182 AVV 0.510204 0.851852
183 7MD 0.509434 0.821429
184 LPA AMP 0.509259 0.843373
185 0WD 0.508772 0.875
186 NAE 0.508475 0.85
187 52H 0.505155 0.804598
188 VMS 0.505155 0.813953
189 54H 0.505155 0.813953
190 NSS 0.50505 0.825581
191 NAQ 0.504202 0.829268
192 EAD 0.504132 0.831325
193 FB0 0.504 0.769231
194 A3N 0.5 0.746835
195 ZID 0.5 0.871795
196 IMO 0.5 0.88
197 AF3 ADP 3PG 0.5 0.797619
198 M24 0.5 0.809524
199 NVA LMS 0.5 0.777778
200 NJP 0.5 0.897436
201 AV2 0.5 0.87013
202 53H 0.5 0.804598
203 J7C 0.5 0.731707
204 ARU 0.5 0.819277
205 ZAS 0.5 0.728395
206 8X1 0.5 0.777778
207 5CA 0.5 0.825581
208 RGT 0.5 0.909091
209 NPW 0.495575 0.843373
210 NDP 0.495575 0.875
211 LEU LMS 0.49505 0.777778
212 DDS 0.494737 0.833333
213 S4M 0.494382 0.655556
214 6FA 0.492188 0.802326
215 DZD 0.491379 0.841463
216 NZQ 0.491228 0.864198
217 P5A 0.490196 0.769231
218 DSZ 0.49 0.825581
219 LSS 0.49 0.786517
220 MAO 0.488889 0.724138
221 DSH 0.488636 0.710843
222 P1H 0.488 0.811765
223 N0B 0.487603 0.781609
224 YLY 0.487395 0.772727
225 ODP 0.486957 0.864198
226 8PZ 0.485714 0.825581
227 9K8 0.485437 0.758242
228 SFD 0.484615 0.776596
229 FAS 0.484615 0.811765
230 FAD 0.484615 0.811765
231 FDA 0.484375 0.795455
232 DAT 0.483871 0.858974
233 5X8 0.483871 0.746835
234 NAJ PZO 0.483051 0.807229
235 G A A A 0.482759 0.829268
236 7MC 0.482143 0.802326
237 62F 0.481203 0.821429
238 PO4 PO4 A A A A PO4 0.480392 0.855263
239 7DD 0.478261 0.932432
240 TXP 0.478261 0.875
241 GJV 0.477778 0.714286
242 NDE 0.47619 0.884615
243 GSU 0.475728 0.804598
244 KAA 0.475728 0.777778
245 5AD 0.474359 0.706667
246 A3G 0.47191 0.759494
247 U A 0.470588 0.8625
248 4TA 0.470085 0.770115
249 XNP 0.470085 0.831325
250 AMP NAD 0.470085 0.858974
251 A G 0.470085 0.839506
252 GP3 0.46875 0.875
253 NDC 0.46875 0.829268
254 6C6 0.46875 0.8375
255 7D7 0.468354 0.705128
256 SFG 0.468085 0.7125
257 YSA 0.46729 0.804598
258 NAJ PYZ 0.467213 0.770115
259 FAY 0.466667 0.821429
260 ETB 0.466667 0.795455
261 DCA 0.466667 0.786517
262 U A G G 0.466102 0.839506
263 A A A 0.466019 0.858974
264 128 0.464286 0.741573
265 RFL 0.463235 0.784091
266 PUA 0.46281 0.841463
267 A7D 0.462366 0.759494
268 FNK 0.459259 0.769231
269 0T1 0.459016 0.786517
270 COA 0.459016 0.806818
271 7C5 0.458716 0.777778
272 A5D 0.458333 0.792208
273 SA8 0.458333 0.674419
274 MHZ 0.457447 0.666667
275 71V 0.456522 0.910256
276 8Q2 0.45614 0.797753
277 NEC 0.455556 0.708861
278 GGZ 0.455446 0.851852
279 SAH 0.453608 0.728395
280 SAI 0.453608 0.698795
281 Y3J 0.451219 0.688312
282 GEK 0.45098 0.722892
283 AS 0.450549 0.884615
284 4YB 0.45045 0.786517
285 GTP 0.45 0.873418
286 SMM 0.45 0.674157
287 6IA 0.44898 0.797619
288 SAM 0.44898 0.678161
289 CAO 0.448 0.8
290 30N 0.448 0.776596
291 COS 0.448 0.808989
292 TAP 0.448 0.935065
293 AMX 0.448 0.795455
294 EEM 0.444444 0.659091
295 CMX 0.444444 0.786517
296 SCO 0.444444 0.786517
297 AAT 0.444444 0.714286
298 P5F 0.443662 0.786517
299 PGS 0.442105 0.910256
300 FCX 0.440945 0.76087
301 ACO 0.440945 0.8
302 FAM 0.440945 0.769231
303 HDV 0.44 0.848101
304 2SA 0.44 0.884615
305 NAP 0.44 0.896104
306 9JJ 0.439716 0.821429
307 APU 0.439655 0.85
308 A U 0.439655 0.82716
309 DA 0.43956 0.833333
310 D5M 0.43956 0.833333
311 HAX 0.4375 0.769231
312 Z5A 0.436508 0.744444
313 DG1 0.436508 0.875
314 1DG 0.436508 0.875
315 V1N 0.436364 0.87013
316 S7M 0.435644 0.678161
317 2MC 0.435115 0.774194
318 649 0.434783 0.769231
319 AAM 0.434783 0.918919
320 WSA 0.434783 0.813953
321 FYN 0.434109 0.806818
322 3KK 0.434109 0.808989
323 NMN AMP PO4 0.433333 0.82716
324 7L1 0.433071 0.8
325 NA0 0.433071 0.884615
326 C2R 0.431818 0.857143
327 AMZ 0.431818 0.868421
328 A3S 0.431579 0.769231
329 MCD 0.430769 0.769231
330 SOP 0.430769 0.788889
331 CA6 0.430769 0.752577
332 COK 0.430769 0.808989
333 OXK 0.430769 0.808989
334 GNH 0.43 0.8625
335 N6P 0.428571 0.866667
336 62X 0.428571 0.637363
337 NVA 2AD 0.428571 0.722892
338 101 0.428571 0.833333
339 F2N 0.427586 0.777778
340 CO6 0.427481 0.808989
341 1VU 0.427481 0.8
342 CMC 0.427481 0.788889
343 NMX 0.427481 0.729167
344 GKE 0.427273 0.841463
345 GDD 0.427273 0.841463
346 GDC 0.427273 0.841463
347 SCA 0.425373 0.808989
348 FA9 0.424658 0.823529
349 K15 0.424528 0.651685
350 A6D 0.424528 0.729412
351 CAJ 0.424242 0.769231
352 SCD 0.424242 0.786517
353 AIR 0.423529 0.853333
354 6K6 0.423077 0.881579
355 A3T 0.42268 0.779221
356 NIA 0.422222 0.783133
357 NHD 0.421488 0.858974
358 MLC 0.421053 0.808989
359 1HE 0.421053 0.791209
360 BCO 0.421053 0.808989
361 IVC 0.421053 0.818182
362 12D 0.421053 0.75
363 3HC 0.421053 0.818182
364 A1S 0.421053 0.788889
365 1CZ 0.42029 0.820225
366 GDP 0.42 0.873418
367 0UM 0.419048 0.666667
368 YE1 0.41791 0.777778
369 COO 0.41791 0.808989
370 MCA 0.41791 0.8
371 CAA 0.41791 0.818182
372 GCP 0.417476 0.851852
373 G1R 0.417476 0.8625
374 SXZ 0.416667 0.697674
375 2CP 0.414815 0.78022
376 MC4 0.414815 0.765957
377 ZDA 0.414141 0.820513
378 KB1 0.412844 0.666667
379 2KQ 0.411765 0.791209
380 BYC 0.411765 0.808989
381 IRC 0.411765 0.818182
382 MGP 0.411765 0.841463
383 CA8 0.411765 0.770833
384 HGG 0.411765 0.808989
385 1GZ 0.411765 0.8
386 3CP 0.411765 0.788889
387 3AD 0.411765 0.763158
388 COW 0.411765 0.8
389 COF 0.411765 0.771739
390 A C A C 0.41129 0.807229
391 N01 0.41129 0.858974
392 S8M 0.409524 0.743902
393 FAQ 0.408759 0.808989
394 BCA 0.408759 0.8
395 4CA 0.408759 0.78022
396 7RP 0.408602 0.878378
397 2VA 0.408163 0.759494
398 6G0 0.407767 0.841463
399 CO7 0.407407 0.808989
400 26A 0.406977 0.725
401 QQX 0.406593 0.857143
402 HXC 0.405797 0.791209
403 GRA 0.405797 0.808989
404 FAI 0.404255 0.868421
405 7RA 0.404255 0.906667
406 GPG 0.40367 0.864198
407 TGC 0.402878 0.8
408 ACK 0.402174 0.815789
409 RP1 0.402174 0.894737
410 QQY 0.402174 0.844156
411 SP1 0.402174 0.894737
412 S0N 0.4 0.769231
413 CIC 0.4 0.788889
414 EO7 0.4 0.813953
415 CO8 0.4 0.791209
416 U A C C 0.4 0.817073
417 SLU 0.4 0.816092
418 APC G U 0.4 0.795181
419 8BR 0.4 0.860759
420 GNP 0.4 0.851852
421 TM1 0.4 0.738636
422 9GM 0.4 0.851852
423 2NE 0.4 0.791209
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1H74; Ligand: ILE; Similar sites found with APoc: 67
This union binding pocket(no: 1) in the query (biounit: 1h74.bio2) has 12 residues
No: Leader PDB Ligand Sequence Similarity
1 2PHN GDP 1.5748
2 3LXD FAD 1.68919
3 1V25 ANP 1.68919
4 6C3C EJ1 2.36486
5 2YG3 FAD 2.36486
6 2R5V HHH 2.36486
7 1ORR NAD 2.36486
8 3X44 PUS 2.36486
9 4D57 ARG AMP 2.36486
10 4LZJ 22H 2.36486
11 1WVG APR 2.36486
12 1EQ2 NAP 2.36486
13 3RFV NAI 2.62172
14 3RFV 15L 2.62172
15 4GKV NAD 2.7027
16 6C8T EQJ 3.04054
17 6C92 EQJ 3.04054
18 2A8X FAD 3.04054
19 4GUT FAD 3.04054
20 4AZJ SEP PLP 3.04054
21 5Z2L NDP 3.26531
22 6CUZ FEV 3.37838
23 2VBF TPP 3.37838
24 1VJO PLP 3.37838
25 3WBF API 3.37838
26 2FCR FMN 3.46821
27 4KXQ APR 3.55872
28 3WQQ NDP 3.71622
29 3WQQ IB3 3.71622
30 4KP7 1UQ 3.71622
31 4KP7 NAP 3.71622
32 4K2M O1G 4.05405
33 3NUB UD0 4.05405
34 6C8R SAH 4.05405
35 1AJS PLA 4.05405
36 5Z21 NAI 4.05405
37 1XG5 NAP 4.30108
38 5UY8 8UM 4.39189
39 5UY8 AMZ 4.39189
40 3L4S NAD 4.39189
41 2GZ3 NAP 4.72973
42 3S1S SAH 5.40541
43 3VC3 C6P 5.81395
44 5NII FAD 6.14887
45 5I60 67W 6.41892
46 3DAA PDD 6.41892
47 6FAA ADP 6.41892
48 2Q0L NAP 6.41892
49 5BSH PRO 6.4982
50 3K7M FAD 6.75676
51 5OE4 3UK 6.75676
52 3OBK PBG 6.75676
53 5JP0 BGC 6.75676
54 5MHB PBG 7.09459
55 1P9B IMO 7.09459
56 4IVN BMX 7.19424
57 5NUE NAD 7.43243
58 3NKS FAD 7.77027
59 2Q16 ITT 7.77027
60 3FSJ D7K 8.78378
61 5VEG FMN 8.98876
62 3PC3 P1T 9.67742
63 3B8X G4M 10.473
64 4YC0 5OF 10.8787
65 3TWO NDP 11.1486
66 1VE3 SAM 12.3348
67 1J5P NAD 13.5135
Pocket No.: 2; Query (leader) PDB : 1H74; Ligand: ILE; Similar sites found with APoc: 81
This union binding pocket(no: 2) in the query (biounit: 1h74.bio2) has 29 residues
No: Leader PDB Ligand Sequence Similarity
1 1LNX URI None
2 5OCM 9RH 1.03093
3 4XO8 KGM 1.26582
4 2HW1 FRU 1.68919
5 6G47 SIA 1.91388
6 6G47 SIA SIA 1.91388
7 5DNC ASN 2.02703
8 4U00 ADP 2.04918
9 5LTJ ADP 2.36486
10 5W6Y TRP 2.36486
11 4CCW VKC 2.7027
12 5MZI FYK 2.7027
13 1F9V ADP 2.88184
14 5DT6 GLU 2.99625
15 3COB ADP 3.04054
16 6A20 ADP 3.04054
17 1G6H ADP 3.11284
18 3AI8 HNQ 3.125
19 3GD8 GOL 3.13901
20 5NXX 3Q7 3.35821
21 2A2C ADP 3.37838
22 2A2C NG1 3.37838
23 1YQT ADP 3.37838
24 2AWN ADP 3.41207
25 1S9A BEZ 3.50195
26 2X5F PLP 3.71622
27 2XT3 ADP 3.71622
28 4ZNO SUC 3.71622
29 1OS7 TAU 3.88693
30 5YW5 ADE 3.91061
31 5TQZ GLC 4
32 2CZL TLA 4.04412
33 2JK0 ASP 4.05405
34 3NHB ADP 4.05405
35 4FRZ ADP 4.05405
36 4YMU ATP 4.09091
37 4QM7 GTP 4.09357
38 5B5S BOG 4.34783
39 2WTN FER 4.38247
40 2OG2 MLI 4.39189
41 2JBM SRT 4.39189
42 3B9Q MLI 4.63576
43 2BOY BHO 4.72441
44 2GK6 ADP 4.72973
45 4MDB RLT 4.88889
46 5GVR LMR 5.12821
47 2F6U CIT 5.12821
48 4R2I ANP 5.2381
49 2PZE ATP 5.24017
50 2R42 FPS 5.40541
51 3V2U ATP 5.40541
52 5YW0 SIN 5.40541
53 3I7S PYR 5.40541
54 2AJ4 ANP 5.74324
55 4A59 AMP 6.08108
56 1JJ7 ADP 6.15385
57 3B5J 12D 6.17284
58 3BP1 GUN 6.2069
59 1NX4 AKG 6.22711
60 5OKU 0L1 6.41892
61 1FNZ A2G 6.75105
62 1QAW TRP 6.75676
63 1WUU ANP 7.01754
64 2HIM ASN 7.09459
65 2ZC0 PMP 7.43243
66 3H4S ADP 8.88889
67 1SOW OXL 9.7973
68 2PYU IMP 9.7973
69 1JI0 ATP 10.4167
70 5Y4R C2E 11.0345
71 2X7I CIT 12.5
72 3ZIA ADP 14.4928
73 1IT7 GUN 14.8649
74 4UTG ANP 15.8784
75 2V2V V12 16.5541
76 2HYQ MAN MAN 17.2131
77 2NU5 NAG 17.2131
78 1XVB BBU 19.5946
79 1OJ4 ANP 22.9682
80 2WW4 ADP 22.9682
81 6MDE MEV 28.3828
Pocket No.: 3; Query (leader) PDB : 1H74; Ligand: ADP; Similar sites found with APoc: 307
This union binding pocket(no: 3) in the query (biounit: 1h74.bio2) has 33 residues
No: Leader PDB Ligand Sequence Similarity
1 1OYJ GSH None
2 2IL4 COA None
3 2IMG MLT None
4 1WAP TRP None
5 5C2N NAG 1.01351
6 5OCM 9RH 1.03093
7 4AOA IK2 1.35135
8 2CJW GDP 1.5625
9 2J5V PCA 1.68919
10 1TKU 5RP 1.68919
11 3MD0 GDP 1.68919
12 3I51 45C 1.85185
13 3G5N PB2 2.02703
14 1ZGS XMM 2.02703
15 6F5W KG1 2.02703
16 1XMV ADP 2.02703
17 4U00 ADP 2.04918
18 1TL2 NDG 2.11864
19 3GJ3 GDP 2.26244
20 3GJ0 GDP 2.26244
21 3GJ5 GDP 2.26244
22 5ZI9 FLC 2.30769
23 5MZN ADP 2.36486
24 5LTJ ADP 2.36486
25 2D7D ADP 2.36486
26 4LC1 GDP 2.36486
27 4HE2 AMP 2.36486
28 3DZD ADP 2.36486
29 2G50 ALA 2.36486
30 3ZFD ANP 2.36486
31 2AOU CQA 2.39726
32 4G86 BNT 2.46479
33 1ION ADP 2.46914
34 2IXE ATP 2.58303
35 1U0J ADP 2.62172
36 5NM7 GLY 2.63158
37 1RRC ADP 2.7027
38 3ITJ CIT 2.7027
39 5K8P 6R8 2.7027
40 4KBF AMP 2.7027
41 3RC3 ANP 2.7027
42 4ADC PLP 2.7027
43 4JZ8 CIT 2.7027
44 5CK5 GDP 2.7027
45 3HP9 CF1 2.7027
46 3F81 STT 2.73224
47 3DKP ADP 2.85714
48 2HT6 GDP 2.87356
49 1F9V ADP 2.88184
50 4E03 ADP 2.91262
51 2B4B COA 2.92398
52 5O2J 2PO 2.9304
53 3W5J GDP 2.94118
54 2W58 ADP 2.9703
55 3COB ADP 3.04054
56 6A20 ADP 3.04054
57 4QOS ADP 3.04054
58 3UDG TMP 3.04054
59 4E3Q PMP 3.04054
60 3WMX THR 3.04054
61 5ZBR ANP 3.04054
62 1W31 SHO 3.04054
63 3EC1 GDP 3.04054
64 3CV2 OXL 3.04054
65 5YKT PMP 3.04054
66 1M1B SPV 3.05085
67 1UYY BGC BGC 3.05344
68 5XH2 NPO 3.05344
69 1G6H ADP 3.11284
70 3AI8 HNQ 3.125
71 3GJ8 GDP 3.26087
72 1G3Q ADP 3.37553
73 2A2C ADP 3.37838
74 2A2C NG1 3.37838
75 5YV5 ADP 3.37838
76 1YQT ADP 3.37838
77 5TSH ADP 3.37838
78 3TBK ANP 3.37838
79 2VVG ADP 3.37838
80 5TSH ANP 3.37838
81 4HSE ADP 3.37838
82 5E9G GLV 3.37838
83 5UXH GFB 3.37838
84 2AWN ADP 3.41207
85 5HCN GCP 3.44828
86 1S9A BEZ 3.50195
87 3IUY AMP 3.50877
88 2IYL GDP 3.52113
89 1BO4 COA 3.57143
90 5BQ5 ADP BEF 3.7037
91 2XT3 ADP 3.71622
92 1GOJ ADP 3.71622
93 4XOE KGM 3.71622
94 1Q8S MAN MMA 3.71622
95 4ZM4 PLP 3.71622
96 2FSH ANP 3.71622
97 1UKG MMA 3.71622
98 1DMH MCT 3.71622
99 1Q8Q MAN MMA 3.71622
100 2PHX MAN MAN 3.71622
101 1V8K ANP 3.71622
102 2I6U CP 3.71622
103 1WOQ BGC 3.74532
104 5U32 GDP 3.81356
105 1B0U ATP 3.81679
106 3B7G ANP 3.91304
107 4JLS 3ZE 3.94737
108 4BQS ADP 3.97727
109 3UIE ANP 4
110 5EYW PGA 4.01606
111 3NHB ADP 4.05405
112 3LRE ADP 4.05405
113 4FRZ ADP 4.05405
114 1Z6T ADP 4.05405
115 1WDI CIT 4.05405
116 2IS6 ADP 4.05405
117 2JK0 ASP 4.05405
118 4YJ1 ADP 4.05405
119 5ZXD ATP 4.05405
120 5VHC BEF ADP 4.05405
121 1OFZ FUC 4.05405
122 1OFZ FUL 4.05405
123 3EXS 5RP 4.0724
124 4YMU ATP 4.09091
125 4QM7 GTP 4.09357
126 4WZ6 ATP 4.13793
127 1XX6 ADP 4.18848
128 1R0X ATP 4.1958
129 5B5S BOG 4.34783
130 2WTN FER 4.38247
131 2OG2 MLI 4.39189
132 4AG5 ADP 4.39189
133 4PJ3 ANP 4.39189
134 1JQN DCO 4.39189
135 2JBM SRT 4.39189
136 3DC4 ADP 4.39189
137 3SZB I1E 4.39189
138 4LJ9 ACP 4.39189
139 4Y4V DAL 4.39189
140 1SNN 5RP 4.40529
141 4PX9 ADP 4.45205
142 2QZ4 ADP 4.58015
143 1VHT BA3 4.58716
144 3B9Q MLI 4.63576
145 2BOY BHO 4.72441
146 2GK6 ADP 4.72973
147 3KJI ADP 4.72973
148 1BG2 ADP 4.72973
149 3EWA ANP 4.72973
150 4U0S ADP 4.72973
151 2NNJ 225 4.72973
152 5L3R GCP 4.77816
153 3BFV ADP 4.79705
154 1H65 GDP 4.81482
155 1VG9 GDP 4.86486
156 1I4D GDP 4.91071
157 1TIQ COA 5
158 3LN9 FLC 5.03597
159 2DPY ADP 5.06757
160 2J0W ASP 5.06757
161 1SVI GDP 5.06757
162 5IRN ADP 5.06757
163 1A8U BEZ 5.06757
164 4Z87 GDP 5.06757
165 3FKQ ATP 5.06757
166 2PL3 ADP 5.08475
167 5GVR LMR 5.12821
168 2F6U CIT 5.12821
169 6AIC AMP 5.14019
170 1Z0A GDP 5.17241
171 4KFU ACP 5.18868
172 2J0V GDP 5.18868
173 4R2I ANP 5.2381
174 2PZE ATP 5.24017
175 3V2U ATP 5.40541
176 2R42 FPS 5.40541
177 3TK1 GDP 5.40541
178 3EZ2 ADP 5.40541
179 1T5C ADP 5.40541
180 4WCX ALA 5.40541
181 2ZJ5 ADP 5.40541
182 4RZ3 ADP 5.42373
183 3CYI ATP 5.45455
184 1GXU 2HP 5.49451
185 3PCJ INO 5.5
186 5BXQ GDP 5.51181
187 2F7C CCU 5.5794
188 2Y7I ARG 5.67686
189 3E70 GDP 5.74324
190 3FWY ADP 5.74324
191 2AJ4 ANP 5.74324
192 4P4M D3T 5.74324
193 1SQ5 ADP 5.74324
194 3MWL 8OX 5.7971
195 4LFL TG6 5.81395
196 1O5O U5P 5.88235
197 2OBM ADP 6.08108
198 2ZR9 DTP 6.08108
199 3SHR CMP 6.08108
200 1QHH ATP 6.08696
201 1JJ7 ADP 6.15385
202 3Q9L ATP 6.15385
203 3B5J 12D 6.17284
204 3BP1 GUN 6.2069
205 1JJV ATP 6.31068
206 2WHX ADP 6.41892
207 4PPF FLC 6.41892
208 2JLR ANP 6.41892
209 3UWV 2PG 6.41892
210 3PNL ADP 6.41892
211 6FAA ADP 6.41892
212 5BN3 ADP 6.41892
213 5TB5 GDP 6.48649
214 5TAR GDP 6.48649
215 3T1O GDP 6.56566
216 1KY3 GDP 6.59341
217 2OFW ADX 6.73077
218 4D0N GDP 6.75676
219 5KUT GDP 6.75676
220 5JP0 BGC 6.75676
221 1QAW TRP 6.75676
222 3HY2 ATP 6.79612
223 2D2F ADP 6.8
224 1YRB GDP 6.87023
225 3A4M ADP 6.92308
226 1HTW ADP 6.96203
227 1WUU ANP 7.01754
228 4BA5 PXG 7.09459
229 5JVB 2PO 7.14286
230 4WOH 4NP 7.22892
231 4DID GDP 7.25389
232 2BFR ADP 7.29167
233 4XGU ADP 7.43243
234 1OXV ANP 7.43243
235 5CSS G3P 7.43243
236 1JW0 GUA 7.43243
237 1XKV ATP 7.43243
238 1RZ1 NAD 7.45342
239 6BYF CIT 7.64706
240 3QDW A2G 7.69231
241 2O0J ADP 7.77027
242 3IO3 ADP 7.77027
243 4BTV RB3 7.84884
244 4YEF 4CQ 7.86517
245 2CBZ ATP 8.01688
246 3GJ7 GDP 8.16327
247 2QX0 PH2 8.1761
248 5IDM ANP 8.37989
249 3DUV KDO 8.39695
250 5OCQ CIT 8.78378
251 2CE7 ADP 8.78378
252 2GKS ADP 8.78378
253 3Q85 GNP 8.78378
254 1B7T ADP 8.78378
255 3H4S ADP 8.88889
256 2O66 FLC 8.88889
257 3GJ4 GDP 9.09091
258 3DEF GDP 9.12162
259 4UOX PLP 9.12162
260 3KP6 SAL 9.45946
261 2H7C SIA 9.45946
262 5F1V 3VN 9.45946
263 5O74 GDP 9.64467
264 5Y6N ADP 9.7973
265 3BER AMP 10.0402
266 5O2Z FLC 10.084
267 5L3W GDP 10.1307
268 1JI0 ATP 10.4167
269 5LB3 ADP 10.473
270 1Z03 OCH 10.473
271 1DS6 GDP 10.5556
272 1A8S PPI 10.6227
273 3AB4 THR 10.6742
274 2DTJ THR 10.6742
275 4YDS ATP 10.9649
276 5Y4R C2E 11.0345
277 2WCI GSH 11.1111
278 1W3T 3GR 11.2245
279 4V03 ADP 11.284
280 5WC2 ADP 11.4865
281 6C90 ADP 11.5385
282 1R6B ADP 11.8243
283 4CVN ADP 12.0419
284 5WPJ NDP 12.1622
285 4QYS PLR 12.1622
286 2RCN GDP 12.1622
287 4Z7X 3CX 12.1849
288 2X7I CIT 12.5
289 4IHQ ADP 12.5
290 5L3V GDP 12.5
291 1VBO MAN MAN MAN 12.7517
292 2CDN ADP 12.9353
293 5TCI MLI 13.1757
294 3ZIA ADP 14.4928
295 3Q72 GNP 15.0602
296 3CH5 GDP 15.3846
297 2KIN ADP 15.5462
298 4UTG ANP 15.8784
299 4DCT GDP 15.8784
300 2V2V V12 16.5541
301 1TH8 ADP 18.9655
302 3BY8 MLT 19.7183
303 3PQC GDP 21.0256
304 5J1J ANP 21.4035
305 1OJ4 ANP 22.9682
306 2WW4 ADP 22.9682
307 2Y65 ADP 35
Pocket No.: 4; Query (leader) PDB : 1H74; Ligand: ADP; Similar sites found with APoc: 64
This union binding pocket(no: 4) in the query (biounit: 1h74.bio1) has 34 residues
No: Leader PDB Ligand Sequence Similarity
1 5KXE 6Y2 None
2 1Y13 BIO 1.65746
3 1GPM AMP 1.68919
4 5FTB ANP 2.02703
5 3KVY R2B 2.02703
6 1M26 GAL A2G 2.25564
7 5JCJ 6JM 2.43056
8 3JQ9 AX1 2.43056
9 4Z2B 4LC 2.7027
10 2XYA 7L4 2.74725
11 1QHG ATP 3.04054
12 4WBD CIT 3.04054
13 6HKE MLT 3.37838
14 4CS9 AMP 3.37838
15 5OVK NDP 3.51562
16 2YPI PGA 3.64372
17 1Q19 SSC 3.71622
18 3OBT SLB 3.71622
19 1KC7 PPR 4.05405
20 3K56 IS3 4.13534
21 1P4A PCP 4.21053
22 1YXM ADE 4.72973
23 3BC9 ACR 4.72973
24 4PC3 GDP 5.06757
25 2I4I AMP 5.06757
26 3P4X ADP 5.06757
27 5LOL GSH 5.11628
28 2VDV SAM 5.28455
29 2IF8 ADP 5.40541
30 5C9P FUC 5.51181
31 5LX9 OLB 5.6338
32 4XJC TTP 5.64972
33 2DVZ GLU 5.74324
34 5W3Y ACO 6.08108
35 1FNZ A2G 6.75105
36 3BD9 A3P 6.75676
37 1Q5H DUD 6.80272
38 5AHW CMP 6.80272
39 5KQA GSH 6.81818
40 5N0L