Receptor
PDB id Resolution Class Description Source Keywords
1HUR 2 Å NON-ENZYME: TRANSPORT HUMAN ADP-RIBOSYLATION FACTOR 1 COMPLEXED WITH GDP, FULL LENGTH NON-MYRISTOYLATED HOMO SAPIENS GDP-BINDING MEMBRANE TRAFFICKIN NON-MYRISTOYLATED PROTEIN TRANSPORT
Ref.: STRUCTURE OF THE HUMAN ADP-RIBOSYLATION FACTOR 1 COMPLEXED WITH GDP. NATURE V. 372 704 1994
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GDP A:1;
B:1;
Valid;
Valid;
none;
none;
submit data
443.201 C10 H15 N5 O11 P2 c1nc2...
MG A:182;
B:182;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1O3Y 1.5 Å NON-ENZYME: TRANSPORT CRYSTAL STRUCTURE OF MOUSE ARF1 (DELTA17-Q71L), GTP FORM MUS MUSCULUS PROTEIN TRANSPORT
Ref.: MOLECULAR MECHANISM OF MEMBRANE RECRUITMENT OF GGA BY ARF IN LYSOSOMAL PROTEIN TRANSPORT NAT.STRUCT.BIOL. V. 10 386 2003
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 199 families.
1 1RRG - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 1HUR - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 1O3Y - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
70% Homology Family (9)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1068 families.
1 2X77 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 1RRG - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 1HUR - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
4 1O3Y - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
5 3N5C - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
6 3AQ4 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
7 4Y0V - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
8 4YLG - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
9 1MR3 - G3D C10 H16 N5 O14 P3 c1nc2c(n1[....
50% Homology Family (19)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 181 families.
1 4V0K - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 4V0L - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
3 2X77 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
4 1RRG - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
5 1HUR - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
6 1O3Y - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
7 1FZQ Kd = 24 nM GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
8 1Z6Y - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
9 1ZJ6 - G3D C10 H16 N5 O14 P3 c1nc2c(n1[....
10 1YZG - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
11 3N5C - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
12 1E0S - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
13 1ZD9 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
14 2AL7 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
15 3AQ4 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
16 4Y0V - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
17 4YLG - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
18 1MR3 - G3D C10 H16 N5 O14 P3 c1nc2c(n1[....
19 4BAS - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GDP; Similar ligands found: 153
No: Ligand ECFP6 Tc MDL keys Tc
1 GDP 1 1
2 GTP 0.909091 1
3 GP3 0.881579 0.973684
4 GNH 0.858974 0.986667
5 GNP 0.839506 0.973684
6 G 0.828947 0.986486
7 5GP 0.828947 0.986486
8 G1R 0.82716 0.986667
9 GCP 0.82716 0.973684
10 GSP 0.817073 0.948718
11 GAV 0.797619 0.961039
12 GMV 0.792683 0.973684
13 G2P 0.77381 0.961039
14 G2R 0.770115 0.961039
15 GDP MG 0.759036 0.923077
16 GP2 0.756098 0.961039
17 GDP BEF 0.75 0.9
18 GDD 0.747253 0.961039
19 GKE 0.747253 0.961039
20 GDC 0.747253 0.961039
21 GPG 0.741573 0.961039
22 G3D 0.732558 0.986486
23 ALF 5GP 0.729412 0.888889
24 Y9Z 0.728261 0.902439
25 GTP MG 0.724138 0.923077
26 BEF GDP 0.724138 0.888889
27 G5P 0.723404 0.973684
28 GFB 0.72043 0.961039
29 GTG 0.72043 0.936709
30 GDR 0.72043 0.961039
31 G4P 0.715909 0.986486
32 GCP G 0.715909 0.935065
33 6CK 0.712766 0.936709
34 G3A 0.712766 0.973684
35 GDP ALF 0.7 0.888889
36 GDP AF3 0.7 0.888889
37 YGP 0.698925 0.901235
38 JB2 0.697917 0.961039
39 GKD 0.697917 0.961039
40 GDX 0.690722 0.973684
41 GPD 0.690722 0.925
42 GMP 0.684211 0.88
43 0O2 0.666667 0.986486
44 G G 0.659574 0.935065
45 JB3 0.656863 0.948718
46 NGD 0.650485 0.961039
47 GDP 7MG 0.636364 0.911392
48 DGI 0.636364 0.923077
49 U2G 0.634615 0.936709
50 GPX 0.634409 0.946667
51 IDP 0.632184 0.972973
52 2MD 0.632075 0.891566
53 CAG 0.62963 0.880952
54 CG2 0.622642 0.936709
55 FEG 0.619048 0.879518
56 MGD 0.614679 0.891566
57 ZGP 0.613208 0.869048
58 GH3 0.612903 0.973333
59 3GP 0.611765 0.946667
60 MD1 0.607143 0.891566
61 PGD 0.59292 0.925
62 DGT 0.591398 0.923077
63 BGO 0.588785 0.924051
64 TPG 0.582609 0.840909
65 DBG 0.582609 0.948718
66 2GP 0.574713 0.96
67 FE9 0.570175 0.776596
68 I2C FE2 CMO CMO 0.566372 0.808989
69 G A A A 0.553571 0.923077
70 MGP 0.553191 0.961039
71 U A G G 0.548673 0.935065
72 G4M 0.548387 0.880952
73 6G0 0.547368 0.961039
74 G1R G1R 0.542373 0.924051
75 P2G 0.527473 0.883117
76 PGD O 0.525 0.850575
77 ADP 0.522222 0.92
78 GGM 0.517544 0.901235
79 DG 0.516484 0.910256
80 DGP 0.516484 0.910256
81 P1G 0.516129 0.871795
82 G G U 0.509259 0.935065
83 G1G 0.508475 0.925
84 IMP 0.505495 0.959459
85 G C 0.504348 0.9
86 GPC 0.491525 0.879518
87 G7M 0.483871 0.948052
88 6AD 0.479592 0.841463
89 ATP 0.473684 0.92
90 G2Q 0.471154 0.961039
91 U G A 0.469697 0.888889
92 5FA 0.46875 0.92
93 AQP 0.46875 0.92
94 GTA 0.468468 0.936709
95 7DD 0.468085 0.906667
96 G G G RPC 0.466102 0.875
97 SGP 0.463158 0.82716
98 01G 0.462963 0.902439
99 B4P 0.457447 0.894737
100 AP5 0.457447 0.894737
101 A2D 0.456522 0.894737
102 G G G C 0.455285 0.9125
103 ACQ 0.454545 0.896104
104 5GP 5GP 0.454545 0.883117
105 ANP 0.454545 0.896104
106 A G C C 0.451613 0.911392
107 APC G U 0.45082 0.886076
108 G U34 0.449153 0.888889
109 DG DG 0.448598 0.865854
110 ITT 0.447917 0.868421
111 BA3 0.446809 0.894737
112 35G 0.444444 0.933333
113 C2E 0.444444 0.921053
114 PCG 0.444444 0.933333
115 MGO 0.441176 0.864198
116 AN2 0.4375 0.907895
117 G C C C 0.4375 0.924051
118 M33 0.43299 0.883117
119 UCG 0.429688 0.911392
120 A G U 0.42963 0.888889
121 ACP 0.428571 0.896104
122 MGQ 0.424528 0.935897
123 7DT 0.424242 0.906667
124 APR 0.424242 0.894737
125 AR6 0.424242 0.894737
126 93A 0.42268 0.833333
127 A4P 0.420168 0.869048
128 SAP 0.42 0.873418
129 AD9 0.42 0.896104
130 AGS 0.42 0.873418
131 G8D 0.42 0.875
132 CA0 0.418367 0.896104
133 ATF 0.417476 0.884615
134 AGO 0.414634 0.888889
135 NIA 0.413043 0.82716
136 MGV 0.412844 0.890244
137 TAT 0.411765 0.884615
138 A1R 0.411215 0.839506
139 ADQ 0.411215 0.871795
140 RGT 0.410714 0.909091
141 CGP 0.409836 0.86747
142 AMP 0.408602 0.893333
143 A 0.408602 0.893333
144 UP5 0.40678 0.873418
145 C2R 0.406593 0.906667
146 AMZ 0.406593 0.918919
147 JBT 0.405882 0.778947
148 A22 0.40566 0.907895
149 25L 0.405405 0.907895
150 ADX 0.40404 0.809524
151 8OD 0.401961 0.946667
152 4TC 0.4 0.851852
153 50T 0.4 0.883117
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1O3Y; Ligand: GTP; Similar sites found: 492
This union binding pocket(no: 1) in the query (biounit: 1o3y.bio2) has 27 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 2W58 ADP 0.000001663 0.64643 None
2 2GJ8 ALF GDP 0.0000000009597 0.63805 None
3 3Q72 GNP 0.0000000007224 0.57443 None
4 4D81 ADP 0.0003348 0.47288 None
5 1UJ2 C5P 0.0001894 0.46635 None
6 1UJ2 ADP 0.0002347 0.46246 None
7 1BO4 COA 0.002863 0.44377 None
8 1UKZ ADP 0.001482 0.43784 None
9 1KO8 6PG 0.0003875 0.43001 None
10 1PTR PRB 0.01199 0.42812 None
11 4GBM A3P 0.004267 0.40493 None
12 2FFQ GSP 0.00000000003289 0.74879 1.80723
13 2Y8E GNP 0.00000000003376 0.7051 1.80723
14 5KSP GDP 0.0000002928 0.62967 1.80723
15 1D2E GDP 0.00000001152 0.58317 1.80723
16 4WEI GLC GAL 0.002177 0.46675 1.80723
17 3BOS CDP 0.00009182 0.41463 1.80723
18 3B7G ANP 0.001139 0.45816 2.40964
19 1CR1 TTP 0.0006787 0.42678 2.40964
20 3BFX A3P 0.003433 0.41905 2.40964
21 1T5C ADP 0.000001268 0.4188 2.40964
22 1R0X ATP 0.0002601 0.4045 2.40964
23 2JBH 5GP 0.02265 0.40351 2.40964
24 4WZ6 ATP 0.000008996 0.59122 3.01205
25 2J0V GDP 0.00000008835 0.53541 3.01205
26 4XGU ADP 0.00005832 0.50181 3.01205
27 4PX9 ADP 0.0002978 0.49817 3.01205
28 3IO3 ADP 0.0000224 0.4778 3.01205
29 2QZ4 ADP 0.00006927 0.43975 3.01205
30 5E5U MLI 0.01188 0.4257 3.01205
31 3BER AMP 0.01239 0.41252 3.01205
32 3BD9 A3P 0.01367 0.40648 3.01205
33 1G7S GDP 0.000000000532 0.76059 3.61446
34 4NCN GTP 0.00000000003519 0.73721 3.61446
35 4TMZ GSP 0.00000000007159 0.72453 3.61446
36 1V8K ANP 0.000001646 0.60239 3.61446
37 1DAR GDP 0.0000000005372 0.59056 3.61446
38 5GJC ATP 0.00004076 0.53417 3.61446
39 2DPY ADP 0.000363 0.50045 3.61446
40 2RGX AP5 0.0003122 0.47728 3.61446
41 2C9O ADP 0.000607 0.44771 3.61446
42 3UIE ANP 0.00004253 0.44311 3.61446
43 1NJF AGS 0.0006215 0.43411 3.61446
44 1NJF ADP 0.0004303 0.42803 3.61446
45 3EWA ANP 0.00005165 0.42203 3.61446
46 2PZE ATP 0.000001567 0.4206 3.61446
47 3DZD ADP 0.0006057 0.41489 3.61446
48 5WRI A3P 0.003247 0.4131 3.61446
49 5WRJ A3P 0.003337 0.41104 3.61446
50 4M7V RAR 0.01581 0.40451 3.61446
51 3BFV ADP 0.000006152 0.57437 4.05904
52 5J1J ANP 0.0001221 0.4684 4.21053
53 3U6B GDP 0.00000000006098 0.83389 4.21687
54 5JBQ GDP 0.0000000001661 0.79796 4.21687
55 4G5G GDP 0.0000000002175 0.79224 4.21687
56 2BVN GNP 0.00000000004412 0.78674 4.21687
57 3U6K GDP 0.0000000005842 0.77123 4.21687
58 4HI0 GDP 0.00000005743 0.61988 4.21687
59 4P3Y GDP 0.000000000046 0.60495 4.21687
60 1D8T GDP 0.000000000164 0.60396 4.21687
61 2HCJ GDP 0.00000000008889 0.59895 4.21687
62 3EZ2 ADP 0.000409 0.49126 4.21687
63 3Q9L ATP 0.0001065 0.49015 4.21687
64 1FP6 ADP 0.0001845 0.48468 4.21687
65 3FKQ ATP 0.0001685 0.48124 4.21687
66 3H86 AP5 0.0008851 0.44881 4.21687
67 1XKV ATP 0.00009884 0.43853 4.21687
68 3QKT ANP 0.0008963 0.43466 4.21687
69 5K5Z ANP 0.0006125 0.43335 4.21687
70 4GOX A3P 0.0008755 0.43323 4.21687
71 5AHO TLA 0.02542 0.41173 4.21687
72 1F2U ATP 0.001037 0.4355 4.72973
73 3WY9 GDP 0.0000000001485 0.81448 4.81928
74 5GOE GDP 0.000000005341 0.70194 4.81928
75 3LRE ADP 0.0000007467 0.65973 4.81928
76 4LPS GDP 0.00000007581 0.6577 4.81928
77 3WYA GDP 0.0000000001575 0.60432 4.81928
78 4ZG4 VO4 ADP 0.000000307 0.57525 4.81928
79 3ZFD ANP 0.0000002087 0.5259 4.81928
80 4V03 ADP 0.00003959 0.52135 4.81928
81 1IWE IMP 0.000274 0.51715 4.81928
82 2GDJ ANP 0.0001676 0.50412 4.81928
83 4IEE AGS 0.0003936 0.49209 4.81928
84 3E70 GDP 0.000001402 0.49172 4.81928
85 5VGR GDP 0.000423 0.46341 4.81928
86 4IOK ADP 0.0003325 0.45788 4.81928
87 4IOK XPO 0.00025 0.45758 4.81928
88 1OS1 PYR 0.001273 0.43644 4.81928
89 1OS1 ATP 0.001302 0.43454 4.81928
90 1P4V GLY 0.008976 0.42981 4.81928
91 2FAH GDP 0.0003444 0.42564 4.81928
92 3FYH ADP 0.001747 0.414 4.81928
93 3CV2 OXL 0.03262 0.40272 4.81928
94 2VOH CIT 0.01093 0.41428 5.09554
95 4FCW ADP 0.0002823 0.41441 5.14469
96 2C78 GNP 0.00000000001113 0.76802 5.42169
97 2C77 GNP 0.000000000004062 0.74983 5.42169
98 5XDR ADP 0.000381 0.48089 5.42169
99 3IIJ ADP 0.000001128 0.47846 5.42169
100 3VX3 ADP 0.0002146 0.47168 5.42169
101 3KTA AP5 0.0004159 0.46858 5.42169
102 1Z6T ADP 0.0004242 0.46335 5.42169
103 1YTM ATP 0.0003099 0.4602 5.42169
104 2QEN ADP 0.0000722 0.45068 5.42169
105 2ZTS ADP 0.0008859 0.44478 5.42169
106 4TTQ ATP 0.00004427 0.4333 5.42169
107 2Y65 ADP 0.00000253 0.42442 5.42169
108 1W5T ADP 0.004292 0.41846 5.42169
109 1W5T ANP 0.003715 0.41402 5.42169
110 4NZ6 DGL 0.02059 0.41142 5.42169
111 4FMS BDP 0.02713 0.40426 5.42169
112 1XEX ATP 0.002324 0.40305 5.42169
113 1GOJ ADP 0.0000003397 0.68088 6.0241
114 1SVI GDP 0.00000003687 0.52864 6.0241
115 1QF5 GDP 0.00007843 0.51189 6.0241
116 2XTN GTP 0.00001114 0.51114 6.0241
117 4HSE ADP 0.0002255 0.49178 6.0241
118 1QF5 RPL 0.005346 0.45742 6.0241
119 4A4Z ANP 0.00162 0.45589 6.0241
120 3DC4 ADP 0.00000165 0.45259 6.0241
121 3KJI ADP 0.0000678 0.44915 6.0241
122 2IXE ATP 0.0003337 0.44451 6.0241
123 3QXC ATP 0.0003636 0.43036 6.0241
124 2YOH WMJ 0.0001653 0.41627 6.0241
125 1JJV ATP 0.00004794 0.40895 6.0241
126 1SQL GUN 0.03001 0.4039 6.16438
127 1GXU 2HP 0.0005324 0.47795 6.59341
128 1SKQ GDP 0.0000000001107 0.82088 6.62651
129 3VMF GTP 0.0000000001328 0.72028 6.62651
130 4PPF FLC 0.0000002893 0.69191 6.62651
131 2CBZ ATP 0.000002116 0.63963 6.62651
132 3NHB ADP 0.000004611 0.60712 6.62651
133 2RCN GDP 0.0000000001984 0.60043 6.62651
134 2ZR9 DTP 0.00002525 0.54435 6.62651
135 4OHY ANP 0.00008381 0.46696 6.62651
136 1S3G AP5 0.0006929 0.45969 6.62651
137 4MKG AP5 0.0008806 0.45512 6.62651
138 4MKF AP5 0.00116 0.45099 6.62651
139 3FVQ ATP 0.0005093 0.45097 6.62651
140 4KFU ACP 0.000001995 0.43823 6.62651
141 2JLR ANP 0.0001603 0.4309 6.62651
142 4YS0 ADP 0.002581 0.42833 6.62651
143 1IN4 ADP 0.0007143 0.41914 6.62651
144 1G41 ADP 0.0002741 0.41787 6.62651
145 5LTJ ADP 0.0001351 0.41729 6.62651
146 1OFH ADP 0.0003551 0.41536 6.62651
147 2JAQ DCP 0.003339 0.40932 6.62651
148 2WHX ADP 0.0000178 0.40859 6.62651
149 1T8U UAP SGN IDS SGN 0.01414 0.40206 6.62651
150 4RD0 GDP 0.00000000000747 0.75265 7.22892
151 1YRB GDP 0.000000003059 0.70276 7.22892
152 1MKY GDP 0.0000000001631 0.60441 7.22892
153 1SQ5 ADP 0.00000794 0.5612 7.22892
154 2C04 GCP 0.000006453 0.54448 7.22892
155 1G3Q ADP 0.00001808 0.54413 7.22892
156 3T34 GDP 0.000004245 0.52836 7.22892
157 2B8W ALF 5GP 0.000005335 0.52665 7.22892
158 4IDN GNP 0.00002327 0.50304 7.22892
159 1G6O ADP 0.0001033 0.50191 7.22892
160 1F5N GNP 0.000005075 0.49852 7.22892
161 5LB3 ADP 0.0003011 0.49793 7.22892
162 5H56 TYD 0.00008516 0.48624 7.22892
163 5H56 ADP 0.00008516 0.48624 7.22892
164 2OBM ADP 0.001117 0.48302 7.22892
165 2WOJ ADP ALF 0.00005737 0.45898 7.22892
166 2QG6 NMN 0.0003381 0.45757 7.22892
167 3FWY ADP 0.0000625 0.45529 7.22892
168 3A4M ADP 0.000002216 0.44479 7.22892
169 2VVG ADP 0.0000005842 0.42688 7.22892
170 4TMK T5A 0.002685 0.42674 7.22892
171 1F9V ADP 0.00001011 0.41947 7.22892
172 1CM0 COA 0.0129 0.40395 7.22892
173 5MVR ADP 0.00001381 0.44931 7.40741
174 1HTW ADP 0.0000103 0.45958 7.59494
175 4OI4 ATP 0.001655 0.42186 7.82609
176 4J0Q GDP 0.00000000004548 0.84028 7.83133
177 5HCN GCP 0.00000001017 0.69938 7.83133
178 4ZKD GDP 0.00000000005749 0.68171 7.83133
179 1TQ4 GDP 0.00000001976 0.6397 7.83133
180 5L3V GDP 0.0000009389 0.59718 7.83133
181 5I34 GDP 0.00001823 0.54395 7.83133
182 5GVR LMR 0.0002519 0.52075 7.83133
183 5BQ5 ADP BEF 0.0001059 0.5014 7.83133
184 4ZNL BEF ADP 0.0001576 0.4992 7.83133
185 4RZ3 ADP 0.0001671 0.48141 7.83133
186 5G41 AP5 0.0003546 0.4782 7.83133
187 5MZN ADP 0.004141 0.44593 7.83133
188 1XMV ADP 0.00005159 0.43018 7.83133
189 1BG2 ADP 0.0000007066 0.42291 7.83133
190 2XAU ADP 0.0005093 0.40553 7.83133
191 2QN6 GDP 0.0000000001033 0.8224 8.43373
192 1WDT GTP 0.0000000006847 0.71177 8.43373
193 2HF9 GSP 0.00000001456 0.66259 8.43373
194 3B9Q MLI 0.0000008385 0.65704 8.43373
195 5IRR GSP 0.0000000435 0.61742 8.43373
196 5FG3 GDP 0.0000000001885 0.58988 8.43373
197 4BQS ADP 0.00002585 0.54385 8.43373
198 5L3R GCP 0.000001329 0.53906 8.43373
199 4YDS ATP 0.00006776 0.53801 8.43373
200 1JWY GDP 0.0000005179 0.52527 8.43373
201 4XTR ADP 0.0001234 0.48218 8.43373
202 3TMK T5A 0.0001527 0.47381 8.43373
203 4R2I ANP 0.001247 0.47282 8.43373
204 4XTR ATP 0.0001289 0.46743 8.43373
205 4XVU ATP 0.0001493 0.46481 8.43373
206 1LVG ADP 0.0000005257 0.46201 8.43373
207 2Q2Y ADP 0.0008628 0.45551 8.43373
208 2Q2Y MKR 0.0009096 0.45332 8.43373
209 1JWY ADP 0.00002291 0.44509 8.43373
210 2OZE AGS 0.0005112 0.42668 8.43373
211 4PJ3 ANP 0.006497 0.41406 8.43373
212 2VF7 ADP 0.0002147 0.41156 8.43373
213 4JBL MET 0.02465 0.40578 8.43373
214 1QF9 C5P 0.00314 0.42749 8.76289
215 1B7T ADP 0.0001012 0.50233 8.97436
216 2AWN ADP 0.000000328 0.69766 9.03614
217 1WF3 GNP 0.000000000597 0.69619 9.03614
218 4PC3 GDP 0.000000008764 0.6819 9.03614
219 5KSZ GCP 0.000001747 0.58459 9.03614
220 4H1V GNP 0.000003572 0.55594 9.03614
221 2VB6 ADP BEF 0.000008463 0.51605 9.03614
222 4PFO ADP 0.00001115 0.51563 9.03614
223 4LYA ATP 0.00008907 0.51105 9.03614
224 1M7G ADX 0.00003287 0.50552 9.03614
225 1M7G ADP 0.00003695 0.49981 9.03614
226 5IRN ADP 0.000102 0.49643 9.03614
227 1M7G AV2 0.0000007156 0.4732 9.03614
228 1KK8 BEF ADP 0.00001363 0.52999 9.09091
229 3CNL GNP 0.0000000003095 0.57989 9.63855
230 5CK5 GDP 0.0000000004821 0.5781 9.63855
231 5AOG IAC 0.007304 0.44604 9.63855
232 2BEK ATP 0.001029 0.43404 9.63855
233 2XT3 ADP 0.000002349 0.42428 9.63855
234 4QRH 0O2 0.000812 0.42314 9.63855
235 5IFS ADP 0.0002136 0.42111 9.63855
236 2KIN ADP 0.000001128 0.41781 10
237 5KUT GDP 0.0000001069 0.53133 10.241
238 4QM7 GTP 0.000005139 0.45509 10.241
239 1IHU ADP 0.0003141 0.45154 10.241
240 1IHU AF3 0.0002537 0.44943 10.241
241 1XP8 AGS 0.00004605 0.4182 10.241
242 3R7F CP 0.0169 0.41675 10.241
243 4PU6 ASP 0.008719 0.42922 10.687
244 1PUJ GNP 0.0000000002958 0.63916 10.8434
245 5L3S GNP 0.000004785 0.51701 10.8434
246 5L3W GDP 0.00001003 0.47354 10.8434
247 3FB4 AP5 0.0007551 0.45805 10.8434
248 5L3S G 0.006395 0.44127 10.8434
249 1RRC ADP 0.0000003713 0.43911 10.8434
250 5J1S ATP 0.001539 0.41712 10.8434
251 1VHT BA3 0.0007338 0.40769 10.8434
252 2PL3 ADP 0.0004437 0.48948 11.4458
253 3P4X ADP 0.00003785 0.42375 11.4458
254 3MD0 GDP 0.0000000001198 0.59244 12.0482
255 1NN5 ANP 0.0001162 0.48217 12.0482
256 1W0J ADP 0.0001052 0.43828 12.0482
257 1ION ADP 0.00008366 0.43605 12.0482
258 5TSH ANP 0.00003063 0.43295 12.0482
259 5H67 ATP 0.008024 0.41759 12.0482
260 1W0J ADP BEF 0.001873 0.40472 12.0482
261 4P4T GDP 0.000001273 0.56896 12.6506
262 3TK1 GDP 0.00000000126 0.55664 12.6506
263 4FRZ ADP 0.000009648 0.41936 12.6506
264 3H4S ADP 0.000003569 0.41819 12.6506
265 4B47 GDP 0.00000000002107 0.85705 13.2231
266 2CJW GDP 0.0000000001205 0.80479 13.253
267 3WXM GTP 0.0000000001584 0.71709 13.253
268 2HT6 GDP 0.0000000000155 0.61704 13.253
269 1Y63 ADP 0.000003055 0.46255 13.253
270 1OE0 TTP 0.005904 0.4039 13.253
271 4JLV ADP 0.0001516 0.40371 13.253
272 4AG5 ADP 0.000004945 0.60438 13.8554
273 5I0H ADP BEF 0.0000003388 0.55589 13.8554
274 2CHG ANP 0.0003864 0.42483 13.8554
275 4IHQ ADP 0.0001426 0.40247 13.8554
276 4LO2 GAL BGC 0.02796 0.40853 14.2857
277 1G7C 5GP 0.00000009625 0.66274 14.4578
278 2OFW ADX 0.0000241 0.52231 14.4578
279 4WOP CTP 0.00009839 0.48152 14.4578
280 1X6V ADP 0.00007363 0.44067 14.4578
281 4CVN ADP 0.00001815 0.56749 14.5985
282 5N69 ADP 0.000004341 0.55897 15.0602
283 2BIF SIN 0.000791 0.46054 15.0602
284 2BIF ANP 0.0004389 0.46054 15.0602
285 1OYY AGS 0.002572 0.44605 15.0602
286 3QF7 ANP 0.0003436 0.43094 15.6627
287 2ZPA ADP 0.000588 0.42235 15.6627
288 1SES AMP 0.01192 0.41761 15.6627
289 3ZS9 ADP ALF 0.00004713 0.46214 15.7895
290 2V7Q ATP 0.00007161 0.43627 16
291 2CK3 ANP 0.002207 0.42745 16
292 2CK3 ADP 0.003712 0.40742 16
293 5M04 GDP 0.00000000001009 0.87309 16.2651
294 2PEZ DAT 0.00002087 0.51566 16.2651
295 2PEZ GGZ 0.00002087 0.44105 16.2651
296 3RLF ANP 0.0007182 0.43677 16.2651
297 4E03 ADP 0.0000939 0.42815 16.2651
298 1G8S MET 0.01335 0.4214 16.2651
299 2NCD ADP 0.00000124 0.63522 16.8675
300 2ZE7 DST 0.002324 0.42084 16.8675
301 3CX8 GSP 0.000000000002756 0.80051 17.4699
302 1ZCB GDP 0.0000000008703 0.68634 17.4699
303 3AB3 GDP 0.000000006776 0.6224 17.4699
304 2IYL GDP 0.000002002 0.59823 17.4699
305 4WZA ADP 0.00009084 0.51777 17.4699
306 4WZA ACP 0.00009084 0.51777 17.4699
307 4LC1 GDP 0.00000001472 0.70265 18.0723
308 1P9B GDP 0.00006808 0.49881 18.0723
309 1R6B ADP 0.0002427 0.41435 18.0723
310 1P9B HDA 0.02268 0.40932 18.0723
311 2J5V PCA 0.02977 0.40441 18.0723
312 1W7J ADP BEF 0.000001339 0.57495 18.543
313 1M7B GTP 0.000000002563 0.67765 18.6747
314 1GWN GTP 0.000000001295 0.65463 18.6747
315 5FTB ANP 0.0001584 0.49324 18.6747
316 4QOS ADP 0.0006236 0.46547 18.6747
317 5FHD ADP ALF 0.0002493 0.46425 18.6747
318 2WKQ GTP 0.000000002787 0.65917 19.8795
319 2W2X GSP 0.000000001244 0.65481 19.8795
320 2FJU GSP 0.000000001854 0.64898 19.8795
321 3SBD GNP 0.000000001771 0.64148 19.8795
322 1RYH GNP 0.00000000116 0.61026 19.8795
323 1KK1 GNP 0.0000000002136 0.5895 19.8795
324 1HE1 AF3 0.00001884 0.56665 19.8795
325 1HE1 GDP 0.000001204 0.56334 19.8795
326 1DS6 GDP 0.00000001981 0.54732 19.8795
327 1I4D GDP 0.00000009356 0.51701 19.8795
328 1E96 GTP 0.0000000009045 0.68564 20.4819
329 4U5X GNP 0.000000002377 0.63317 20.4819
330 2ZEJ GDP 0.00000008148 0.60699 20.4819
331 2CE7 ADP 0.0001458 0.42569 20.4819
332 1AZT GSP 0.000000000002694 0.80092 21.6867
333 2XTZ GSP 0.00000000000178 0.79811 21.6867
334 1CS4 GSP 0.000000000001991 0.71965 21.6867
335 3DEF GDP 0.00001386 0.53596 21.6867
336 1FNN ADP 0.0005116 0.4552 21.6867
337 1D5C GDP 0.000000006344 0.60418 22.2222
338 3GJ8 GDP 0.0000000001178 0.79187 22.2892
339 4HAT GNP 0.000000000005543 0.78446 22.2892
340 5UWI GNP 0.000000000004731 0.78397 22.2892
341 5UWT GNP 0.000000000004809 0.78367 22.2892
342 5UWP GNP 0.0000000000059 0.78332 22.2892
343 3GJ0 GDP 0.0000000006036 0.77054 22.2892
344 3GJ7 GDP 0.000000000614 0.77018 22.2892
345 5UWU GNP 0.000000000004811 0.72048 22.2892
346 5UWH GNP 0.000000000004848 0.72034 22.2892
347 5UWQ GNP 0.000000000004938 0.72008 22.2892
348 5UWR GNP 0.000000000005167 0.71937 22.2892
349 5UWW GNP 0.000000000005274 0.7191 22.2892
350 5UWJ GNP 0.000000000005292 0.71902 22.2892
351 5UWO GNP 0.000000000005447 0.71862 22.2892
352 5DIF GNP 0.000000000005992 0.71721 22.2892
353 1IBR GNP 0.0000000000103 0.70918 22.2892
354 5UWS GNP 0.000000000006585 0.70052 22.2892
355 5DI9 GNP 0.000000000007087 0.6994 22.2892
356 1MH1 GNP 0.0000000002009 0.6642 22.2892
357 3CH5 GDP 0.00000000008472 0.62932 22.2892
358 3GJ5 GDP 0.0000000001629 0.6216 22.2892
359 5BXQ GDP 0.0000000001925 0.61936 22.2892
360 3GJ3 GDP 0.0000000004575 0.59355 22.2892
361 3GJ4 GDP 0.000000000721 0.58866 22.2892
362 3EC1 GDP 0.000000003852 0.57994 22.2892
363 1G4U GDP 0.000001933 0.56103 22.2892
364 1G4U AF3 0.0001462 0.52352 22.2892
365 2FNA ADP 0.0002238 0.46182 22.2892
366 2Z48 NGA 0.01199 0.43838 22.2892
367 2Z49 AMG 0.01586 0.4223 22.2892
368 3GJX GTP 0.00000000001102 0.76862 22.8916
369 4R43 GDP 0.0001584 0.50532 22.8916
370 1ZUI SKM 0.00008154 0.49494 22.8916
371 3REF GDP 0.00000002894 0.62484 23.494
372 3WYF GTP 0.000000000003303 0.7939 24.0964
373 3M1I GTP 0.000000000004304 0.78568 24.0964
374 1K6M AGS 0.0001603 0.46354 25.3012
375 4P32 ADP 0.0007082 0.43083 25.9036
376 5M7P ADP 0.0006909 0.42129 25.9036
377 1GRN AF3 0.0000002085 0.66743 26.506
378 4YC7 GNP 0.000000008027 0.63172 26.506
379 1GRN GDP 0.0000001323 0.61982 26.506
380 2WMO GTP 0.000000001648 0.60646 26.506
381 1A4R GDP 0.00000001732 0.60163 26.506
382 1A4R GNH 0.00000002423 0.58754 26.506
383 2NGR GDP 0.0000001033 0.53502 26.506
384 4DID GDP 0.0000001045 0.53268 26.506
385 4ITR GDP 0.000001197 0.52921 26.506
386 2NGR AF3 0.0000000943 0.49555 26.506
387 1TAD GDP 0.000000000008614 0.77963 27.1084
388 1TAD ALF 0.000000000008614 0.68455 27.1084
389 1NF3 GNP 0.000000001541 0.64397 27.1084
390 1GOT GDP 0.000000008338 0.62991 27.1084
391 3ZIA ATP 0.00007067 0.43033 27.5362
392 3ZIA ADP 0.0001943 0.42847 27.5362
393 2GCO GNP 0.000000002706 0.62073 27.8607
394 2GCN GDP 0.00000008741 0.58999 27.8607
395 1X1R GDP 0.000000005046 0.65747 28.0899
396 1BH2 GSP 0.000000000003327 0.79706 28.3133
397 3T12 GDP ALF 0.00000000001532 0.76218 28.3133
398 1FQJ ALF 0.00000002444 0.72471 28.3133
399 1FQK ALF 0.00000007884 0.70443 28.3133
400 2ODE ALF GDP 0.000000000004473 0.69337 28.3133
401 5KDO GDP 0.000000002785 0.67611 28.3133
402 1FQJ GDP 0.000000002128 0.66399 28.3133
403 1Y3A GDP 0.000000002215 0.66327 28.3133
404 1FQK GDP 0.000000003398 0.65564 28.3133
405 1GP2 GDP 0.00000001071 0.63515 28.3133
406 3T1O GDP 0.0000000009992 0.60851 28.3133
407 5UQW GDP 0.000000002372 0.6482 28.5714
408 1SVK ALF GDP 0.000000000002045 0.80919 28.9157
409 3ZQ6 ADP ALF 0.00004404 0.49282 28.9157
410 5TB5 GDP 0.000000001349 0.72982 29.1892
411 5TAR GDP 0.000000002584 0.7061 29.1892
412 4KVG GTP 0.0000000002758 0.70708 30.1205
413 3Q85 GNP 0.0000000001555 0.60556 30.7229
414 5HR5 ADP 0.0002108 0.43201 30.7229
415 5HR5 FLC 0.003955 0.41824 30.7229
416 4HDO GNP 0.0000000001038 0.72793 31.3253
417 4HDQ GNP 0.000000001801 0.67616 31.3253
418 3X1Z GNP 0.0000000001614 0.65448 31.3253
419 1H65 GDP 0.0001084 0.46538 31.3253
420 5DHF GNP 0.000000000005547 0.7184 31.5789
421 1NVV GNP 0.00000000008468 0.73163 31.9277
422 2EW1 GNP 0.00000000004917 0.73124 31.9277
423 3DDC GNP 0.0000000002171 0.71455 31.9277
424 2UZI GTP 0.0000000002763 0.70705 31.9277
425 1WQ1 AF3 0.0000003666 0.66726 31.9277
426 4D0G GTP 0.000000001784 0.65764 31.9277
427 1XTQ GDP 0.000000003058 0.65752 31.9277
428 3KUD GDP 0.00000002344 0.60344 31.9277
429 1WQ1 GDP 0.0000001024 0.59484 31.9277
430 3T5G GDP 0.000000003584 0.59115 31.9277
431 1CLU DBG 0.00000004519 0.47542 31.9277
432 5O2T GSP 0.0000000004759 0.65045 31.9527
433 1GUA GNP 0.0000000001357 0.66952 32.0988
434 2BME GNP 0.000000000007144 0.77302 32.5301
435 4LX0 BEF GDP 0.00000000002964 0.75067 32.5301
436 4C4P GNP 0.0000000001033 0.72803 32.5301
437 1NVU GTP 0.0000000001109 0.72674 32.5301
438 2D7C GTP 0.0000000001309 0.72053 32.5301
439 5JCZ GDP 0.00000001146 0.65831 32.5301
440 2F9L GDP 0.00000009696 0.59582 32.5301
441 1UAD GNP 0.0000000002484 0.70897 33.1325
442 3E5H GNP 0.0000000006007 0.69303 33.1325
443 2HV8 GTP 0.0000000008214 0.68738 33.1325
444 4DSU GDP 0.000000002911 0.66745 33.1325
445 1U8Z GDP 0.00000001373 0.63071 33.1325
446 5UFQ GNP 0.000000005059 0.62232 33.1325
447 2A9K GDP 0.00000001582 0.58869 33.1325
448 1YQT ADP 0.00001632 0.41076 33.1325
449 2OM2 GDP 0.00000000326 0.67318 33.3333
450 1KAO GDP 0.00000002246 0.58256 33.5329
451 2C5L GTP 0.0000000001065 0.72747 33.7349
452 4K81 GTP 0.0000000004013 0.70637 33.7349
453 1ZC3 GNP 0.000000001258 0.68267 33.7349
454 5E95 GDP 0.00000008127 0.62926 33.7349
455 2EFE GNH 0.00000002415 0.57516 33.7349
456 1CXZ GSP 0.0000000002889 0.69011 34.3373
457 5WDR GNP 0.0000000001571 0.6675 34.3373
458 3LXR GDP 0.0000001912 0.62942 34.3373
459 3CPJ GDP 0.00000003258 0.56777 34.3373
460 4D0N GDP 0.00000003457 0.53731 34.3373
461 2G77 GDP 0.0000000001261 0.75463 34.9398
462 1EK0 GNP 0.00000000005077 0.73763 34.9398
463 1TU3 GNP 0.00000000005545 0.73604 34.9398
464 2G77 AF3 0.0000004139 0.65989 34.9398
465 5XCO GDP 0.00000001466 0.58156 34.9398
466 1G16 GDP 0.000000279 0.56907 34.9398
467 3MJH GTP 0.00000000001365 0.72156 35.5422
468 3RWO GDP 0.00000001054 0.64133 35.5422
469 5JCP GDP ALF 0.000000004792 0.68412 36.1446
470 4XSH GSP 0.000000005327 0.67285 36.1446
471 1TX4 ALF GDP 0.000000001616 0.6689 36.1446
472 1KY3 GDP 0.0000000244 0.57118 36.1446
473 1OW3 GDP 0.0000001453 0.55651 36.1446
474 5HPY GDP 0.0000001687 0.55589 36.1446
475 5IRC GDP 0.0000002234 0.53069 36.1446
476 1KMQ GNP 0.0000000003459 0.69642 36.747
477 4XOI GTP 0.0000000006305 0.6716 36.747
478 3TNF GNP 0.00000000006081 0.74078 38.5542
479 3QBT GNP 0.000000000006412 0.73343 38.5542
480 4LHW GNP 0.000000000517 0.66093 38.5542
481 3RAB GNP 0.00000000007766 0.72996 39.1566
482 4DKX GDP 0.0000000002433 0.78985 39.759
483 3BC1 GNP 0.0000000002139 0.71167 39.759
484 3SFV GDP 0.0000000202 0.60498 40.9639
485 5SZH GNP 0.00000000004534 0.74296 41.5663
486 3NKV GNP 0.0000000001286 0.72085 41.5663
487 3TKL GTP 0.0000000002296 0.68864 41.5663
488 3WYG GTP 0.000000000002391 0.79979 42.7711
489 1LFD GNP 0.0000000001465 0.7185 43.7126
490 2FH5 GTP 0.000000000004447 0.7481 43.9759
491 3PQC GDP 0.000001028 0.59534 43.9759
492 4DCT GDP 0.000000004203 0.71771 45.7831
Pocket No.: 2; Query (leader) PDB : 1O3Y; Ligand: GTP; Similar sites found: 5
This union binding pocket(no: 2) in the query (biounit: 1o3y.bio1) has 28 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 2IL4 COA 0.01411 0.40018 None
2 5FJJ MAN 0.0006285 0.45796 3.61446
3 4O48 ASP 0.01149 0.42714 6.62651
4 2F5X ASP 0.02951 0.40569 7.22892
5 1QHH ATP 0.01739 0.403 12.0482
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