-->
Receptor
PDB id Resolution Class Description Source Keywords
1IS3 1.45 Å NON-ENZYME: BINDING LACTOSE AND MES-LIGANDED CONGERIN II CONGER MYRIASTER COMPLEX WITH LACTOSE AND MES SUGAR BINDING PROTEIN
Ref.: CRYSTAL STRUCTURE OF A CONGER EEL GALECTIN (CONGERI 1.45 A RESOLUTION: IMPLICATION FOR THE ACCELERATED OF A NEW LIGAND-BINDING SITE FOLLOWING GENE DUPLICA J.MOL.BIOL. V. 321 879 2002
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
LAT A:401;
Valid;
none;
submit data
342.296 C12 H22 O11 C([C@...
MES A:777;
Invalid;
none;
submit data
195.237 C6 H13 N O4 S C1COC...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1IS3 1.45 Å NON-ENZYME: BINDING LACTOSE AND MES-LIGANDED CONGERIN II CONGER MYRIASTER COMPLEX WITH LACTOSE AND MES SUGAR BINDING PROTEIN
Ref.: CRYSTAL STRUCTURE OF A CONGER EEL GALECTIN (CONGERI 1.45 A RESOLUTION: IMPLICATION FOR THE ACCELERATED OF A NEW LIGAND-BINDING SITE FOLLOWING GENE DUPLICA J.MOL.BIOL. V. 321 879 2002
Members (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 510 families.
1 1WLW - GAL GLC n/a n/a
2 1IS3 - LAT C12 H22 O11 C([C@@H]1[....
3 1IS4 - LAT C12 H22 O11 C([C@@H]1[....
4 1WLD - GAL BGC n/a n/a
70% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 391 families.
1 1WLW - GAL GLC n/a n/a
2 1IS3 - LAT C12 H22 O11 C([C@@H]1[....
3 1IS4 - LAT C12 H22 O11 C([C@@H]1[....
50% Homology Family (10)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 298 families.
1 1C1L - GAL BGC n/a n/a
2 2YMZ Ka = 6000 M^-1 LAT C12 H22 O11 C([C@@H]1[....
3 3OYW Kd = 78 uM TDG C12 H22 O10 S C([C@@H]1[....
4 2ZKN - GAL BGC n/a n/a
5 1GAN - NDG GAL n/a n/a
6 1WLW - GAL GLC n/a n/a
7 1IS3 - LAT C12 H22 O11 C([C@@H]1[....
8 1SLC - NAG MAN GAL BMA NDG MAN NAG GAL n/a n/a
9 1SLB - NAG MAN GAL MAN MAN NAG GAL n/a n/a
10 1SLT - NDG GAL n/a n/a
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: LAT; Similar ligands found: 333
No: Ligand ECFP6 Tc MDL keys Tc
1 GLA GLA 1 1
2 GAL BGC 1 1
3 GLC GAL 1 1
4 BMA GAL 1 1
5 LBT 1 1
6 BGC GAL 1 1
7 CBI 1 1
8 MAL 1 1
9 CBK 1 1
10 BGC BMA 1 1
11 N9S 1 1
12 MAB 1 1
13 LAT 1 1
14 GLA GAL 1 1
15 B2G 1 1
16 BMA BMA BMA 0.909091 1
17 GLA GAL GLC 0.909091 1
18 GLC BGC BGC 0.909091 1
19 GLC BGC BGC BGC 0.909091 1
20 GLC GLC GLC GLC GLC 0.909091 1
21 CT3 0.909091 1
22 BGC GLC GLC GLC 0.909091 1
23 BGC BGC BGC BGC 0.909091 1
24 CTT 0.909091 1
25 CTR 0.909091 1
26 GLC GAL GAL 0.909091 1
27 MAN BMA BMA BMA BMA BMA 0.909091 1
28 BGC BGC BGC GLC 0.909091 1
29 CEY 0.909091 1
30 B4G 0.909091 1
31 BGC BGC BGC 0.909091 1
32 GLC GLC BGC 0.909091 1
33 CE5 0.909091 1
34 BGC BGC BGC BGC BGC BGC 0.909091 1
35 BGC BGC BGC BGC BGC BGC BGC BGC BGC 0.909091 1
36 BMA BMA BMA BMA BMA BMA 0.909091 1
37 GLC GLC GLC GLC GLC GLC GLC GLC GLC 0.909091 1
38 GLA GAL BGC 0.909091 1
39 MLR 0.909091 1
40 MAN BMA BMA 0.909091 1
41 BGC GLC GLC GLC GLC GLC GLC 0.909091 1
42 BMA BMA BMA BMA BMA 0.909091 1
43 BGC BGC GLC 0.909091 1
44 MAN MAN BMA BMA BMA BMA 0.909091 1
45 BGC GLC GLC 0.909091 1
46 BGC BGC BGC BGC BGC 0.909091 1
47 MT7 0.909091 1
48 GLC BGC BGC BGC BGC 0.909091 1
49 CE6 0.909091 1
50 MTT 0.909091 1
51 CE8 0.909091 1
52 MAN BMA BMA BMA BMA 0.909091 1
53 GLC BGC GLC 0.909091 1
54 DXI 0.909091 1
55 GLC BGC BGC BGC BGC BGC 0.909091 1
56 CEX 0.909091 1
57 GAL GAL GAL 0.909091 1
58 BMA MAN BMA 0.909091 1
59 BGC GLC GLC GLC GLC 0.909091 1
60 GLA GAL GAL 0.816327 1
61 BGC BGC BGC BGC BGC BGC BGC BGC 0.754717 1
62 BMA BMA GLA BMA BMA 0.689655 1
63 XYT 0.685185 0.767442
64 LAT GLA 0.680851 1
65 GLC GLC GLC BGC 0.672414 1
66 U63 0.647059 0.891892
67 MMA MAN 0.64 0.942857
68 DR5 0.64 0.942857
69 GLA EGA 0.634615 0.942857
70 GAL FUC 0.615385 0.941176
71 2M4 0.612245 1
72 BGC GAL FUC 0.610169 0.970588
73 FUC GAL GLC 0.610169 0.970588
74 8B7 0.610169 0.970588
75 GLC GAL FUC 0.610169 0.970588
76 LAT FUC 0.610169 0.970588
77 BGC GLA GAL FUC 0.609375 0.970588
78 BQZ 0.608696 0.909091
79 BGC GAL NAG GAL 0.606061 0.733333
80 GAL NAG GAL GLC 0.606061 0.733333
81 BMA BMA BMA BMA 0.603448 0.941176
82 M3M 0.6 1
83 LB2 0.6 1
84 NGR 0.6 1
85 MAN GLC 0.6 1
86 MAL EDO 0.592593 0.942857
87 BGC BGC BGC XYS GAL 0.588235 0.942857
88 XYS BGC BGC BGC BGC XYS BGC BGC BGC 0.588235 0.942857
89 XYS BGC BGC XYS BGC XYS BGC BGC BGC 0.588235 0.942857
90 BGC BGC BGC XYS BGC BGC 0.588235 0.942857
91 LAT NAG GAL 0.588235 0.733333
92 GLC GAL NAG GAL 0.588235 0.733333
93 NGA GAL BGC 0.587302 0.733333
94 TRE 0.581395 1
95 ABD 0.57971 0.75
96 NLC 0.578947 0.733333
97 NDG GAL 0.578947 0.733333
98 GAL NDG 0.578947 0.733333
99 5GO 0.578947 0.66
100 DEL 0.574074 0.970588
101 MVP 0.571429 0.733333
102 GAL NGA GLA BGC GAL 0.571429 0.733333
103 GAL BGC BGC XYS 0.569231 0.942857
104 SGA BGC 0.568965 0.66
105 BGC BGC 0.566038 0.914286
106 BMA BMA 0.566038 0.914286
107 GLC GLC XYP 0.557377 1
108 BGC BGC XYS BGC 0.552239 0.942857
109 NAG GAL BGC 0.552239 0.733333
110 GLA GAL BGC 5VQ 0.551724 0.891892
111 G2F BGC BGC BGC BGC BGC 0.55 0.868421
112 GLA MBG 0.54902 0.942857
113 GLC ACI G6D BGC 0.547945 0.733333
114 GLC G6D ACI GLC 0.547945 0.733333
115 GLC ACI GLD GLC 0.547945 0.733333
116 GLC G6D ADH GLC 0.547945 0.733333
117 GLC BGC BGC BGC BGC BGC BGC 0.545455 1
118 BGC BGC BGC GLC BGC BGC 0.545455 1
119 BMA BMA MAN 0.535714 1
120 MAN MAN BMA 0.535714 1
121 NGA GLA GAL BGC 0.535211 0.733333
122 GAL BGC BGC BGC XYS BGC XYS 0.533333 0.942857
123 BGC BGC BGC XYS BGC XYS GAL 0.533333 0.942857
124 BGC BGC BGC XYS BGC XYS XYS 0.528571 0.942857
125 BGC BGC XYS BGC XYS BGC XYS 0.528571 0.942857
126 GLC BGC BGC XYS BGC XYS XYS 0.528571 0.942857
127 BMA MAN MAN MAN 0.525424 1
128 GLA GAL GLC NBU 0.52459 0.846154
129 FUC BGC GAL 0.52459 0.970588
130 GLC GLC G6D ACI GLC GLC GLC 0.519481 0.733333
131 GLC ACI GLD GAL 0.519481 0.702128
132 GLC ACI G6D GLC 0.519481 0.702128
133 BGC BGC BGC FRU 0.516129 0.868421
134 DOM 0.509091 0.942857
135 G3I 0.507937 0.767442
136 LMU 0.507937 0.785714
137 DMU 0.507937 0.785714
138 UMQ 0.507937 0.785714
139 OXZ BGC BGC 0.507937 0.6875
140 G2I 0.507937 0.767442
141 LMT 0.507937 0.785714
142 GAL XYS XYS BGC BGC BGC XYS GAL BGC 0.506329 0.942857
143 BGC BGC XYS BGC GAL XYS BGC XYS GAL 0.506329 0.942857
144 GAL BGC BGC BGC XYS XYS 0.506329 0.942857
145 GLC BGC BGC XYS BGC XYS XYS GAL GAL 0.506329 0.942857
146 GLC BGC BGC XYS BGC XYS XYS GAL 0.506329 0.942857
147 FMO 0.5 0.868421
148 MAN BMA NAG 0.5 0.733333
149 SOR GLC GLC 0.5 0.970588
150 GLA GAL NAG 0.5 0.733333
151 8VZ 0.5 0.673469
152 ACR GLC GLC GLC 0.493827 0.702128
153 GLC GLC DAF BGC 0.493827 0.702128
154 GLC GLC ACI G6D GLC GLC 0.493827 0.702128
155 ARE 0.493827 0.733333
156 GLC GLC AGL HMC GLC 0.493827 0.702128
157 AAO 0.493827 0.733333
158 GLC GLC XYS 0.492308 0.970588
159 MAN BMA MAN 0.491803 1
160 CGC 0.491525 0.941176
161 5QP 0.491228 0.885714
162 GAL MBG 0.490909 0.942857
163 MDM 0.490909 0.942857
164 RZM 0.490909 0.688889
165 M13 0.490909 0.942857
166 GAL NAG MAN 0.485294 0.733333
167 SOR GLC GLC GLC 0.484848 0.970588
168 GLO GLC GLC GLC 0.484848 0.970588
169 6UZ 0.484848 0.846154
170 LAG 0.484848 0.6
171 GAL BGC NAG GAL 0.478873 0.733333
172 GTM BGC BGC 0.477612 0.868421
173 10M 0.477612 0.733333
174 MAN MAN MAN MAN 0.476923 1
175 MAN MAN BMA MAN 0.476923 1
176 GLA GAL NAG FUC GAL GLC 0.47619 0.717391
177 GAL GAL SO4 0.47619 0.66
178 NAG BMA 0.47619 0.653061
179 GAL NGA 0.47541 0.733333
180 A2G GAL 0.47541 0.733333
181 GAL A2G 0.47541 0.733333
182 GLA BMA 0.472727 1
183 GLC BGC 0.472727 1
184 GAL GAL 0.472727 1
185 GLA GLC 0.472727 1
186 BGC GLA 0.472727 1
187 GAL GLC 0.472727 1
188 GLA BGC 0.472727 1
189 BMA GLA 0.472727 1
190 BMA MAN 0.472727 1
191 MAN MAN 0.472727 1
192 BGC GLC 0.472727 1
193 MLB 0.472727 1
194 GLC GLC 0.472727 1
195 MAN BMA 0.472727 1
196 LAK 0.472727 1
197 NPJ 0.470588 0.622642
198 FUC GAL NAG GAL BGC 0.469136 0.717391
199 GAL GLC NAG GAL FUC 0.469136 0.717391
200 GLC NAG GAL GAL FUC 0.469136 0.717391
201 MAN MAN MAN GLC 0.46875 1
202 ABL 0.466667 0.702128
203 FRU GAL 0.465517 0.842105
204 BMA FRU 0.465517 0.842105
205 DAF BGC 0.464789 0.733333
206 DAF GLC 0.464789 0.733333
207 TM6 0.463768 0.916667
208 BGC SGC BGC SGC BGC SGC BGC SGC 0.463768 0.916667
209 LSE 0.462687 0.6875
210 FUC GLA GLA 0.460317 0.970588
211 GAL GAL FUC 0.460317 0.970588
212 FUC GAL GLA 0.460317 0.970588
213 GLA GLA FUC 0.460317 0.970588
214 GLA GAL FUC 0.460317 0.970588
215 IFM BMA 0.457627 0.711111
216 9MR 0.457627 0.744186
217 IFM BGC 0.457627 0.711111
218 BMA IFM 0.457627 0.711111
219 BGC OXZ 0.457627 0.666667
220 RCB 0.457143 0.622642
221 GLO GLC GLC 0.457143 0.942857
222 MAN MAN MAN 0.45614 1
223 GLC GLC GLC GLC BGC 0.45614 1
224 GLC GLC GLC GLC GLC BGC 0.45614 1
225 BMA MAN MAN 0.45614 1
226 GLC GLC GLC 0.45614 1
227 WOO 0.454545 0.848485
228 GIV 0.454545 0.848485
229 BGC 0.454545 0.848485
230 ALL 0.454545 0.848485
231 GAL 0.454545 0.848485
232 GLA 0.454545 0.848485
233 GLC 0.454545 0.848485
234 GXL 0.454545 0.848485
235 BMA 0.454545 0.848485
236 MAN 0.454545 0.848485
237 ACI GLD GLC GAL 0.453333 0.733333
238 DAF BGC GLC 0.453333 0.733333
239 DAF GLC GLC 0.453333 0.733333
240 MGL SGC BGC BGC 0.450704 0.868421
241 MGL SGC GLC GLC 0.450704 0.868421
242 CM5 0.450704 0.891892
243 MAN MAN MAN BMA MAN 0.450704 1
244 BGC BGC SGC MGL 0.450704 0.868421
245 MAN MNM 0.45 0.702128
246 GLC DMJ 0.45 0.695652
247 A2G GAL BGC FUC 0.45 0.717391
248 NOJ GLC 0.45 0.695652
249 NOY BGC 0.45 0.702128
250 BMA MAN MAN MAN MAN 0.449275 1
251 GCS GCS 0.448276 0.767442
252 PA1 GCS 0.448276 0.767442
253 M5S 0.447761 1
254 MAN BMA MAN MAN MAN 0.447761 1
255 TXT 0.447368 0.767442
256 GAC 0.447368 0.767442
257 GLC GAL NAG GAL FUC FUC 0.447059 0.702128
258 BGC GAL NAG GAL FUC FUC 0.447059 0.702128
259 GAL NAG GAL NAG GAL NAG 0.445946 0.673469
260 NAG GAL GAL NAG GAL 0.445946 0.6875
261 NAG GAL GAL NAG 0.445946 0.6875
262 MA4 0.444444 0.891892
263 QV4 0.444444 0.733333
264 MAN DGO 0.440678 0.914286
265 3SA 0.44 0.733333
266 Z6J 0.439024 0.742857
267 GLC GLC GLC PO4 SGC GLC 0.439024 0.66
268 AHR 0.439024 0.742857
269 RIB 0.439024 0.742857
270 FUB 0.439024 0.742857
271 32O 0.439024 0.742857
272 T6P 0.438596 0.767442
273 MMA 0.4375 0.857143
274 MBG 0.4375 0.857143
275 GYP 0.4375 0.857143
276 AMG 0.4375 0.857143
277 MAN G63 0.435484 0.653061
278 GDQ GLC 0.435484 0.666667
279 4MU BGC BGC 0.434211 0.767442
280 ISX 0.433333 0.761905
281 MAN 7D1 0.431034 0.888889
282 ACR 0.43038 0.733333
283 QPS 0.43038 0.733333
284 GAL MGC 0.428571 0.702128
285 4MU BGC BGC BGC BGC 0.428571 0.767442
286 GAL NDG FUC 0.422535 0.717391
287 FUC NDG GAL 0.422535 0.717391
288 HMC AGL GLC 0.421053 0.717391
289 KHO 0.421053 0.888889
290 GCS GCS GCS 0.419355 0.767442
291 GCS GCS GCS GCS GCS 0.419355 0.767442
292 GCS GCS GCS GCS GCS GCS 0.419355 0.767442
293 GAL NAG GAL 0.418919 0.702128
294 NGT GAL 0.41791 0.66
295 GAL NGT 0.41791 0.66
296 P3M 0.41791 0.767442
297 GLC GAL NAG GAL FUC A2G 0.417582 0.673469
298 A2G GAL NAG FUC GAL GLC 0.417582 0.673469
299 TUR 0.416667 0.842105
300 BTU 0.416667 0.842105
301 GLC FRU 0.416667 0.842105
302 GLA MAN ABE 0.414286 0.916667
303 NAG NAG BMA 0.413333 0.634615
304 NAG NDG BMA 0.413333 0.634615
305 ACR GLC GLC GLC GLC 0.4125 0.702128
306 ACR GLC 0.4125 0.702128
307 AHR AHR AHR AHR AHR AHR 0.410714 0.857143
308 FUB AHR AHR 0.410714 0.857143
309 VAM 0.409836 0.868421
310 GLF B8D 0.409836 0.775
311 DAF GLC DAF GLC GLC 0.409639 0.702128
312 ACI GLD GLC ACI G6D BGC 0.409639 0.702128
313 AC1 GLC AC1 BGC 0.409639 0.702128
314 ACI G6D GLC ACI G6D BGC 0.409639 0.702128
315 BGC GLC AC1 GLC GLC GLC AC1 0.409639 0.702128
316 ACI GLD GLC GLC GLC ACI GLD GLC GAL 0.409639 0.702128
317 MAN MMA MAN 0.409091 0.942857
318 FUB AHR 0.407407 0.857143
319 AHR AHR 0.407407 0.857143
320 G6D GLC ACI GLD GLC ACI GLD GLC BGC 0.406977 0.653061
321 4U0 0.406593 0.66
322 BGC BGC SSG PIH 0.405063 0.767442
323 GLA MAN RAM ABE 0.405063 0.891892
324 G1P 0.403846 0.697674
325 GL1 0.403846 0.697674
326 XGP 0.403846 0.697674
327 M1P 0.403846 0.697674
328 GLC IFM 0.403226 0.727273
329 MAN IFM 0.403226 0.727273
330 MAN MAN MAN MAN MAN MAN MAN 0.402597 1
331 XZZ BGC BGC 0.402439 0.702128
332 ACG 0.402299 0.695652
333 FUC GAL 0.4 0.941176
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1IS3; Ligand: LAT; Similar sites found with APoc: 433
This union binding pocket(no: 1) in the query (biounit: 1is3.bio1) has 11 residues
No: Leader PDB Ligand Sequence Similarity
1 5FPX GLY SER SER HIS HIS HIS HIS HIS None
2 2GJ5 VD3 None
3 1N5S ADL None
4 4IGH 1EA None
5 4IGH ORO None
6 4IGH FMN None
7 4WN5 MVC None
8 1OGX EQU None
9 1KGI T4A None
10 5AYT L6Y None
11 1OGZ EQU None
12 1UUO ORO None
13 1UUO BRF None
14 1UUO FMN None
15 2Z6C FMN None
16 4K55 H6P None
17 1NYW DAU None
18 2J9C ATP None
19 3NW7 LGV None
20 3DJV C3P None
21 2YG2 S1P None
22 4IAW LIZ None
23 5KJZ PCG None
24 4X6X S74 None
25 4BVA T3 None
26 2CM4 RCL None
27 1KDK DHT None
28 3E85 BSU None
29 3TCT 3MI None
30 4J6W CTP None
31 6GR0 F8W None
32 3FW4 CAQ None
33 6GNO XDI None
34 4QRH 0O2 None
35 6EWZ APC None
36 4IEN GDP None
37 3AGC RCC None
38 5DKK FMN None
39 2YIP YIO None
40 2UX9 FMN None
41 3N0Y APC None
42 2WLG SOP None
43 1Y7P RIP None
44 3MQG ACO None
45 4BVM PLM None
46 4BVM VCA None
47 2GQS C2R None
48 3TAY MN0 1.48148
49 4HSJ 6PC 1.48148
50 5IH9 6BF 1.48148
51 5X8G S0N 1.48148
52 4ORM 2V6 1.48148
53 4ORM FMN 1.48148
54 4ORM ORO 1.48148
55 4X5S AZM 1.48148
56 4KU7 PCG 1.48148
57 4NTK ZSP 1.65289
58 4NTM 2K8 1.65289
59 4YHQ G10 2.0202
60 6D61 4AA 2.22222
61 2XMY CDK 2.22222
62 5ML3 DL3 2.22222
63 4WW8 VD9 2.22222
64 4OMJ 2TX 2.22222
65 3BZ3 YAM 2.22222
66 1OLM VTQ 2.22222
67 3FC2 IBI 2.22222
68 3PG7 PTY 2.22222
69 6FA4 D1W 2.22222
70 1GT4 UNA 2.22222
71 5F2T PLM 2.22222
72 3A6T 8OG 2.32558
73 4I54 1C1 2.54958
74 1TT8 PHB 2.96296
75 5VC5 96M 2.96296
76 1YKD CMP 2.96296
77 4MVK ACE VAL PHE PHE ALA GLU ASP NH2 2.96296
78 1ZM1 BGC BGC BGC 2.96296
79 3ETH ATP 2.96296
80 4OLT GCS GCS GCS GCS GCS GCS 2.96296
81 1NW4 IMH 2.96296
82 5YU3 NAD 2.96296
83 5YU3 PRO 2.96296
84 5DEY 59T 2.96296
85 5FBN 5WF 2.96296
86 1H4H XYP XYS XYP 2.96296
87 3CQD ATP 2.96296
88 3OBK PBG 2.96296
89 5W0N UPU 2.96296
90 3H9A PPY 3.29218
91 5EZU MYR 3.37079
92 3PFG TLO 3.7037
93 3PFG SAM 3.7037
94 4D5B ACX 3.7037
95 3H7J PPY 3.7037
96 4L4J NAG NAG BMA MAN NAG 3.7037
97 4MNS 2AX 3.7037
98 6BHQ NAG NAG FUL BMA MAN MAN NAG GAL 3.7037
99 3ILR IXD 3.7037
100 3ILR SGN 3.7037
101 3ILR SGN IXD 3.7037
102 4AG8 AXI 3.7037
103 3E8T UQ8 3.7037
104 4PU5 ANP 3.7037
105 1T7Q 152 3.7037
106 1T7Q COA 3.7037
107 4P42 PEE 3.7037
108 5DS8 GLY 5CT GLY ALA 3.7037
109 6CDG PRO GLY LEU TRP LYS SER 3.7037
110 2ZYI STE 3.7037
111 2IFW ACE PHE LYS PHE PSA LEU AAR 3.7037
112 5DUB GLY 5GG GLY ALA 3.7037
113 1DMY AZM 3.7037
114 1NE6 SP1 3.7037
115 3VHE 42Q 3.7037
116 4HKP 16B 3.7037
117 4ITH RCM 3.7037
118 3EEL 53T 3.7037
119 2YAK OSV 3.7037
120 3PNA CMP 3.7037
121 4HKP TKW 3.7037
122 4QA8 PJZ 3.7037
123 4OCJ NDG 3.7037
124 2AXR ABL 3.7037
125 4MP8 NAD 4.44444
126 4MP8 MLI 4.44444
127 2AG4 OLA 4.44444
128 2AG4 LP3 4.44444
129 5HA0 LTD 4.44444
130 5DRB 5FJ 4.44444
131 6MPT C30 4.44444
132 2XK9 XK9 4.44444
133 2Y3S TIR 4.44444
134 5GP0 GPP 4.44444
135 5N87 N66 4.44444
136 4GJ3 0XP 4.44444
137 4QCK ASD 4.44444
138 1UMZ BGC BGC XYS BGC XYS GAL 4.44444
139 5NBP BGC BGC BGC 4.44444
140 3KV4 OGA 4.44444
141 5JKG 6LF 4.44444
142 4OCT AKG 4.44444
143 3SLS 77D 4.44444
144 1AJ0 SAN 4.44444
145 1AJ0 PH2 4.44444
146 4COQ SAN 4.44444
147 5UC4 83S 4.44444
148 4B7P 9UN 4.44444
149 1EWF PC1 4.44444
150 4M0R 644 4.44444
151 5EH0 5NW 4.44444
152 3ZXR IQ1 4.44444
153 3IS2 FAD 4.44444
154 3HMO STU 4.44444
155 3ZXR P3S 4.44444
156 1XNK XS2 4.44444
157 2XSB GDL 4.44444
158 3DNT ATP 4.44444
159 1PX8 XYP 4.44444
160 3D72 FAD 4.44444
161 5FLJ QUE 4.44444
162 3B00 16A 4.44444
163 2V2V V12 4.44444
164 1OPB RET 4.47761
165 1KJM ALA GLN PHE SER ALA SER ALA SER ARG 5
166 5A65 TPP 5.18518
167 1ZB6 GST 5.18518
168 1ZB6 DIN 5.18518
169 3DLG GWE 5.18518
170 5YBN AKG 5.18518
171 1VA6 ADP 5.18518
172 1VA6 P2S 5.18518
173 1DZK PRZ 5.18518
174 5IXG OTP 5.18518
175 3MTX PGT 5.18518
176 5ANU 58T 5.18518
177 5C3R HMU 5.18518
178 5C3R AKG 5.18518
179 2A1L PCW 5.18518
180 1F52 ADP 5.18518
181 6FE1 V14 5.18518
182 3M3R BCD 5.18518
183 5EO8 TFU 5.18518
184 5KEW 6SB 5.18518
185 3JRS A8S 5.18518
186 3KDJ A8S 5.18518
187 2BWA GLC BGC 5.18518
188 3OZ2 OZ2 5.18518
189 3STD MQ0 5.18518
190 6G9I CXX 5.18518
191 3JU6 ANP 5.18518
192 4QDC ASD 5.18518
193 4U0W 16G 5.18518
194 1J3R 6PG 5.18518
195 6D28 NEC 5.18518
196 3PP0 03Q 5.18518
197 5D2R 56W 5.18518
198 3P7N FMN 5.18518
199 5OPJ AHR 5.18518
200 3KV5 OGA 5.18518
201 3PTQ NFG 5.18518
202 1UU6 BGC BGC BGC BGC 5.18518
203 3T1A 5MA 5.18518
204 4S3F 43W 5.18518
205 5MJA 7O3 5.18518
206 4A4X JUP 5.18518
207 5NCF 8T5 5.30973
208 5AIG VPR 5.6
209 1BHX ASP PHE GLU GLU ILE 5.71429
210 5UR6 8KM 5.92593
211 2E56 MYR 5.92593
212 2ZMF CMP 5.92593
213 6CLV 6MB 5.92593
214 1TFZ 869 5.92593
215 2Q0D ATP 5.92593
216 2OVW CBI 5.92593
217 3OJI PYV 5.92593
218 1D5Z ACE ALC ARG ALA ODA SER LEU NH2 5.92593
219 3EEB IHP 5.92593
220 1GQG DCD 5.92593
221 1ZZ7 S0H 5.92593
222 5BV6 35G 5.92593
223 6H36 FKE 5.92593
224 4G7A AZM 5.92593
225 5DXI TRE 5.92593
226 5E2N V14 5.92593
227 4R3U 5AD 5.92593
228 4J7Q B7N 5.92593
229 5LJB RTL 5.92593
230 6GIN IR2 5.92593
231 2JAQ DCP 5.92593
232 5DX9 T6P 5.92593
233 2YKL NLD 5.92593
234 1MHC FME TYR PHE ILE ASN ILE LEU THR LEU 6.06061
235 5TBM 79A 6.08696
236 4IPH 1FJ 6.50407
237 6E08 NAP 6.66667
238 1QY1 PRZ 6.66667
239 4J36 1HR 6.66667
240 1ODM ASV 6.66667
241 4OPC FDA 6.66667
242 2JEQ GAL BGC BGC BGC XYS BGC XYS 6.66667
243 1I82 BGC BGC 6.66667
244 3W68 VIV 6.66667
245 1R5L VIV 6.66667
246 4USI ATP 6.66667
247 4JH6 FCN 6.66667
248 1MH5 HAL 6.66667
249 4J36 FAD 6.66667
250 4WOE ADP 6.66667
251 4BG4 ADP 6.66667
252 1Q79 3AT 6.66667
253 5BU3 4W9 6.66667
254 3MHA Z69 6.66667
255 5XQW 8EU 6.66667
256 1MJJ HAL 6.66667
257 2IGA XX2 6.66667
258 1J09 GLU 6.66667
259 2IGA XX3 6.66667
260 3RJY GLC 7.40741
261 3PQB VGP 7.40741
262 3RWP ABQ 7.40741
263 5LXT ACP 7.40741
264 5FP3 3JI 7.40741
265 5EW9 5VC 7.40741
266 1DY4 SNP 7.40741
267 4HK8 XYP XYP XYP XYP XYP XYP 7.40741
268 3HDY GDU 7.40741
269 3HDY FAD 7.40741
270 3HDY FDA 7.40741
271 3OGV PTQ 7.40741
272 3FW3 ETS 7.40741
273 6F6D AKG 7.40741
274 1E8G FAD 7.40741
275 4XCZ T3Q 7.40741
276 5HCF BGC 7.40741
277 1KJ8 ATP 7.40741
278 1KJ8 GAR 7.40741
279 1E8G FCR 7.40741
280 4NFN 2KC 7.40741
281 2V58 LZJ 7.40741
282 4D06 NAR 7.40741
283 5VCV 1N1 7.40741
284 5DVI BGC 7.40741
285 5B09 4MX 7.69231
286 1UNB AKG 8.14815
287 1UNB PN1 8.14815
288 4P8K FAD 8.14815
289 4P8K 38C 8.14815
290 5XS3 VAL ARG SER ARG ARG CYS LEU ARG LEU 8.14815
291 2XXP DSL 8.14815
292 3E2M E2M 8.14815
293 1NWW HPN 8.14815
294 4ZU4 4TG 8.14815
295 4YGF AZM 8.14815
296 3WDX BGC BGC GLC 8.14815
297 5XEG AKG 8.14815
298 4NG2 OHN 8.14815
299 2PFC PLM 8.14815
300 6D6L FY4 8.14815
301 3GE7 AFQ 8.14815
302 1URX AAL GAL AAL GLA 8.14815
303 6EOZ 58K 8.14815
304 6EOZ AKG 8.14815
305 4MLO PAM 8.14815
306 5HMR FDZ 8.14815
307 3ACL 3F1 8.14815
308 4WUJ FMN 8.14815
309 1LEK GLU GLN TYR LYS PHE TYR SER VAL 8.14815
310 2HKA C3S 8.46154
311 3MF2 AMP 8.88889
312 1GP6 DH2 8.88889
313 1GP6 SIN 8.88889
314 1GP6 QUE 8.88889
315 4H2X G5A 8.88889
316 4H2V AMP 8.88889
317 3G08 FEE 8.88889
318 2VFT SOR 8.88889
319 3VQ2 LP4 LP5 MYR DAO 8.88889
320 1S4M LUM 8.88889
321 1ST0 GTG 8.88889
322 5CJF 520 8.88889
323 4D1J DGJ 8.88889
324 6C1S EFV 8.88889
325 3QUZ QUV 8.88889
326 5FKP 6UL 8.88889
327 5A61 3PO 8.88889
328 4H2W AMP 8.88889
329 3RUG DB6 8.88889
330 6D6W GCU 8.88889
331 3RGA LSB 8.88889
332 4H2W 5GP 8.88889
333 5TPV TYD 9.15033
334 4EES FMN 9.56522
335 3UN3 G16 9.62963
336 5H2D ERG 9.62963
337 2AGC DAO 9.62963
338 5W4W 9WG 9.62963
339 1OJK GLC BGC 9.62963
340 4U03 GTP 9.62963
341 4U03 TLL 9.62963
342 4XIZ LPP 9.62963
343 1Z03 OCH 9.62963
344 2D0N PRO SER ILE ASP ARG SER THR LYS PRO 10.1695
345 5FXD H7Y 10.3704
346 2GC0 PAN 10.3704
347 5NW7 9C2 10.3704
348 5ZTN CUR 10.3704
349 5UR1 YY9 10.3704
350 2WA4 069 11.1111
351 4YZC STU 11.1111
352 4WHZ 3NL 11.1111
353 3LVW GSH 11.1111
354 3TYZ PAB 11.1111
355 3TYZ XHP 11.1111
356 2AMV BIN 11.1111
357 4HWS 1B3 11.1111
358 2FLI DX5 11.1111
359 1M15 ARG 11.1111
360 1M15 ADP 11.1111
361 5X7Q GLC GLC GLC GLC GLC 11.1111
362 5X7Q GLC GLC GLC GLC 11.1111
363 4M1U A2G MBG 11.4286
364 3ZO7 K6H 11.7021
365 1QIN GIP 11.8519
366 1EM6 CP4 11.8519
367 5MZI FYK 11.8519
368 5MZI FAD 11.8519
369 2Z77 HE7 11.8519
370 2JLD AG1 11.8519
371 4ZU5 THM 11.8519
372 5YIC 8VO 11.8519
373 5DJU FMN 11.8519
374 3QRC SCR 12.5926
375 4KYS VIB 12.5926
376 5W10 CMP 12.5926
377 4K3H 1OM 12.5926
378 5YW0 SIN 12.5926
379 1P0Z FLC 12.9771
380 4LA7 A1O 13.3333
381 4WVO 3UZ 13.3333
382 4RGA 3PV 13.3333
383 5AYI BGC 13.3333
384 5LUN OGA 13.3333
385 5LUN ARG 13.3333
386 5KR7 6X9 13.3333
387 5IXH OTP 14.0741
388 2OBD 2OB 14.0741
389 5U98 1KX 14.1414
390 5NKB 8ZT 14.8148
391 5HES 032 14.8148
392 5JSP DQY 14.8148
393 5C0C ARG GLN PHE GLY PRO ASP TRP ILE VAL ALA 14.8148
394 5K21 6QF 14.8148
395 1N1D C2G 15.5039
396 1U0A BGC BGC BGC BGC 15.5556
397 5NEA 8V8 15.5556
398 5Y72 DST 15.5556
399 5VNF VAL THR SER VAL VAL 15.5556
400 3QT6 2P0 15.5556
401 4TWL ASC 15.5556
402 5EPQ OLA 16.2963
403 3AKK ADP 16.2963
404 2IUW AKG 17.037
405 6FXR AKG 17.037
406 2HRL SIA GAL SIA BGC NGA CEQ 17.3228
407 5LIA 6XN 17.7778
408 5ZM4 AKG 18.5185
409 5ZM4 9FU 18.5185
410 4RF7 ARG 19.2593
411 3EKK GS2 19.2593
412 3BRN SRO 20
413 1PN0 IPH 20.7407
414 1PN0 FAD 20.7407
415 1KQW RTL 20.8955
416 5OO5 UUA 20.9677
417 5ENQ 5QE 21.4815
418 3M3E GAL A2G NPO 22.2222
419 1PZO CBT 22.2222
420 5NBW 8SK 22.963
421 2IO8 ADP 22.963
422 4NV7 COA 23.7037
423 3AMN CBK 24.4444
424 3AMN CBI 24.4444
425 5H5A 6OU 25.9259
426 6E2B PT7 26.3158
427 1QKQ MAN 26.6667
428 3FW9 SLX 27.4074
429 4IID NOJ 27.4074
430 5SVV FMN 28.1481
431 2IV2 2MD 32.5926
432 3VV1 GAL FUC 38.5185
433 5H9P TD2 48.1481
Pocket No.: 2; Query (leader) PDB : 1IS3; Ligand: LAT; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 1is3.bio1) has 11 residues
No: Leader PDB Ligand Sequence Similarity
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