Receptor
PDB id Resolution Class Description Source Keywords
1IUB 2.31 Å NON-ENZYME: BINDING FUCOSE-SPECIFIC LECTIN FROM ALEURIA AURANTIA (HG-DERIVATIVE FORM) ALEURIA AURANTIA HG MAD LECTIN RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE RSGI STRUCTURAL GENOMICS SUGAR BINDING PROTEIN
Ref.: CRYSTAL STRUCTURE OF FUCOSE-SPECIFIC LECTIN FROM ALEURIA AURANTIA BINDING LIGANDS AT THREE OF ITS FIVE SUGAR RECOGNITION SITES BIOCHEMISTRY V. 42 11093 2003
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
CL A:412;
A:422;
Invalid;
Invalid;
none;
none;
submit data
35.453 Cl [Cl-]
FUL A:401;
A:402;
Valid;
Valid;
none;
none;
submit data
164.156 C6 H12 O5 C[C@H...
SO4 A:411;
Invalid;
none;
submit data
96.063 O4 S [O-]S...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1OFZ 1.5 Å NON-ENZYME: BINDING CRYSTAL STRUCTURE OF FUNGAL LECTIN: SIX-BLADED BETA-PROPELLER FOLD AND NOVEL FUCOSE RECOGNITION MODE FOR A LEURIA AURANTIA LECTIN ALEURIA AURANTIA SUGAR-BINDING PROTEIN LECTIN AAL FUCOSE ALEURIA AURANTIA LECTIN
Ref.: CRYSTAL STRUCTURE OF FUNGAL LECTIN: SIX-BLADED {BETA}-PROPELLER FOLD AND NOVEL FUCOSE RECOGNITION MODE FOR ALEURIA AURANTIA LECTIN J.BIOL.CHEM. V. 278 27059 2003
Members (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 510 families.
1 1OFZ Kd = 24.1 uM FUL C6 H12 O5 C[C@H]1[C@....
2 1IUC - FUL C6 H12 O5 C[C@H]1[C@....
3 1IUB - FUL C6 H12 O5 C[C@H]1[C@....
4 5MXC - MFU C7 H14 O5 C[C@H]1[C@....
70% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 391 families.
1 1OFZ Kd = 24.1 uM FUL C6 H12 O5 C[C@H]1[C@....
2 1IUC - FUL C6 H12 O5 C[C@H]1[C@....
3 1IUB - FUL C6 H12 O5 C[C@H]1[C@....
4 5MXC - MFU C7 H14 O5 C[C@H]1[C@....
50% Homology Family (9)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 298 families.
1 4D4U Kd = 91.9 uM FUC C6 H12 O5 C[C@H]1[C@....
2 4AGI - SFU C7 H14 O4 Se C[C@H]1[C@....
3 5EO8 - TFU C7 H14 O4 Se C[C@H]1[C@....
4 5H47 - FSW C8 H16 O4 Se C[C@H]1[C@....
5 5EO7 - SFU C7 H14 O4 Se C[C@H]1[C@....
6 1OFZ Kd = 24.1 uM FUL C6 H12 O5 C[C@H]1[C@....
7 1IUC - FUL C6 H12 O5 C[C@H]1[C@....
8 1IUB - FUL C6 H12 O5 C[C@H]1[C@....
9 5MXC - MFU C7 H14 O5 C[C@H]1[C@....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: FUL; Similar ligands found: 9
No: Ligand ECFP6 Tc MDL keys Tc
1 FCB 1 1
2 FUC 1 1
3 FCA 1 1
4 XXR 1 1
5 G6D 1 1
6 RAM 1 1
7 RM4 1 1
8 FUL 1 1
9 FUF 0.424242 0.846154
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1OFZ; Ligand: FUL; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 1ofz.bio1) has 9 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 1OFZ; Ligand: FUL; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 1ofz.bio1) has 12 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 1OFZ; Ligand: FUL; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 1ofz.bio1) has 8 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 4; Query (leader) PDB : 1OFZ; Ligand: FUC; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 1ofz.bio1) has 12 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 5; Query (leader) PDB : 1OFZ; Ligand: FUC; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 5) in the query (biounit: 1ofz.bio1) has 13 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 6; Query (leader) PDB : 1OFZ; Ligand: FUC; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 6) in the query (biounit: 1ofz.bio1) has 13 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 7; Query (leader) PDB : 1OFZ; Ligand: FUL; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 7) in the query (biounit: 1ofz.bio1) has 8 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 8; Query (leader) PDB : 1OFZ; Ligand: FUL; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 8) in the query (biounit: 1ofz.bio1) has 12 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 9; Query (leader) PDB : 1OFZ; Ligand: FUL; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 9) in the query (biounit: 1ofz.bio1) has 8 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 10; Query (leader) PDB : 1OFZ; Ligand: FUC; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 10) in the query (biounit: 1ofz.bio1) has 12 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 11; Query (leader) PDB : 1OFZ; Ligand: FUL; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 11) in the query (biounit: 1ofz.bio1) has 8 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 12; Query (leader) PDB : 1OFZ; Ligand: FUL; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 12) in the query (biounit: 1ofz.bio1) has 11 residues
No: Leader PDB Ligand Sequence Similarity
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