Receptor
PDB id Resolution Class Description Source Keywords
1K12 1.9 Å NON-ENZYME: BINDING FUCOSE BINDING LECTIN ANGUILLA ANGUILLA BETA BARREL PROTEIN CARBOHYDRATE COMPLEX SUGAR BINDING PROTEIN
Ref.: A NOVEL FUCOSE RECOGNITION FOLD INVOLVED IN INNATE IMMUNITY. NAT.STRUCT.BIOL. V. 9 628 2002
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
CA A:160;
Part of Protein;
none;
submit data
40.078 Ca [Ca+2...
CL A:301;
Invalid;
none;
submit data
35.453 Cl [Cl-]
FUC A:159;
Valid;
none;
submit data
164.156 C6 H12 O5 C[C@H...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1K12 1.9 Å NON-ENZYME: BINDING FUCOSE BINDING LECTIN ANGUILLA ANGUILLA BETA BARREL PROTEIN CARBOHYDRATE COMPLEX SUGAR BINDING PROTEIN
Ref.: A NOVEL FUCOSE RECOGNITION FOLD INVOLVED IN INNATE IMMUNITY. NAT.STRUCT.BIOL. V. 9 628 2002
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 473 families.
1 1K12 - FUC C6 H12 O5 C[C@H]1[C@....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 355 families.
1 1K12 - FUC C6 H12 O5 C[C@H]1[C@....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 272 families.
1 1K12 - FUC C6 H12 O5 C[C@H]1[C@....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: FUC; Similar ligands found: 9
No: Ligand ECFP6 Tc MDL keys Tc
1 G6D 1 1
2 XXR 1 1
3 FUL 1 1
4 FUC 1 1
5 RAM 1 1
6 FCA 1 1
7 RM4 1 1
8 FCB 1 1
9 FUF 0.424242 0.846154
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1K12; Ligand: FUC; Similar sites found: 19
This union binding pocket(no: 1) in the query (biounit: 1k12.bio1) has 10 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 5ML3 DL3 0.02599 0.40881 None
2 3QP8 HL0 0.01432 0.40107 None
3 4INB 1F6 0.01766 0.41002 2.73973
4 4ZGP ADP 0.01047 0.41946 3.16456
5 5K5M 68T 0.01187 0.41321 3.16456
6 1LWJ ACG 0.03017 0.40052 3.16456
7 4Q0L V14 0.01959 0.42137 3.79747
8 4OMJ 2TX 0.01419 0.41958 3.79747
9 1G3M A3P 0.03393 0.41663 3.79747
10 1G3M PCQ 0.03393 0.41663 3.79747
11 1OLM VTQ 0.02429 0.40275 3.79747
12 4MUV PCG 0.01897 0.40121 6.33803
13 3FQ8 PMP 0.00652 0.4347 6.96203
14 1YIQ PQQ 0.01563 0.41138 7.59494
15 4XSH NAI 0.006087 0.44575 8.22785
16 5NTW 98N 0.01358 0.42216 8.22785
17 1IND EOT 0.006893 0.40799 16.4557
18 3D5Z FUB AHR AHR 0.009658 0.41225 17.7215
19 5IXH OTP 0.03248 0.41361 27.2152
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