Receptor
PDB id Resolution Class Description Source Keywords
1LBX 2.4 Å EC: 3.1.3.25 CRYSTAL STRUCTURE OF A TERNARY COMPLEX OF DUAL ACTIVITY FBPASE/IMPASE (AF2372) FROM ARCHAEOGLOBUS FULGIDUS WITH C ALCIUM IONS AND D-MYO-INOSITOL-1-PHOSPHATE ARCHAEOGLOBUS FULGIDUS DUAL ACTIVITY FBPASE IMPASE ARCHAEAL PHOSPHATASE TERNARY COMPLEX WITH METAL AND SUBSTRATE HYDROLASE
Ref.: CRYSTAL STRUCTURE OF A DUAL ACTIVITY IMPASE/FBPASE (AF2372) FROM ARCHAEOGLOBUS FULGIDUS. THE STORY OF A MOBILE LOOP. J.BIOL.CHEM. V. 277 22863 2002
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
CA A:290;
A:291;
B:590;
B:591;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
none;
submit data
40.078 Ca [Ca+2...
IPD A:295;
B:595;
Valid;
Valid;
none;
none;
submit data
258.12 C6 H11 O9 P [C@H]...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1LBZ 2.2 Å EC: 3.1.3.25 CRYSTAL STRUCTURE OF A COMPLEX (P32 CRYSTAL FORM) OF DUAL ACTIVITY FBPASE/IMPASE (AF2372) FROM ARCHAEOGLOBUS F ULGIDUS WITH 3 CALCIUM IONS AND FRUCTOSE-1,6 BISPHOSPHATE ARCHAEOGLOBUS FULGIDUS DUAL ACTIVITY FBPASE IMPASE ARCHAEAL PHOSPHATASE SUBSTRATE COMPLEX HYDROLASE
Ref.: CRYSTAL STRUCTURE OF A DUAL ACTIVITY IMPASE/FBPASE (AF2372) FROM ARCHAEOGLOBUS FULGIDUS. THE STORY OF A MOBILE LOOP. J.BIOL.CHEM. V. 277 22863 2002
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 5 families.
1 1LBY - F6P C6 H13 O9 P C([C@@H]1[....
2 1LBX - IPD C6 H11 O9 P [C@H]1([C@....
3 1LBZ - FBP C6 H14 O12 P2 C([C@@H]1[....
70% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 5 families.
1 1LBY - F6P C6 H13 O9 P C([C@@H]1[....
2 1LBX - IPD C6 H11 O9 P [C@H]1([C@....
3 1LBZ - FBP C6 H14 O12 P2 C([C@@H]1[....
50% Homology Family (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 1G0H - IPD C6 H11 O9 P [C@H]1([C@....
2 1G0I - INS C6 H12 O6 C1(C(C(C(C....
3 1LBY - F6P C6 H13 O9 P C([C@@H]1[....
4 1LBX - IPD C6 H11 O9 P [C@H]1([C@....
5 1LBZ - FBP C6 H14 O12 P2 C([C@@H]1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: IPD; Similar ligands found: 6
No: Ligand ECFP6 Tc MDL keys Tc
1 LIP 1 1
2 IPD 1 1
3 I4D 0.571429 0.9
4 ITP 0.451613 0.870968
5 IP2 0.433333 0.870968
6 2IP 0.413793 0.870968
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1LBZ; Ligand: FBP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 1lbz.bio1) has 22 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 1LBZ; Ligand: FBP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 1lbz.bio1) has 23 residues
No: Leader PDB Ligand Sequence Similarity
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